Alloiococcus otitidis open reading frames (orfs) encoding polypeptide antigens, immunogenic compositions and uses thereof

ABSTRACT

The present invention relates to the complete genomic sequence of Gram-positive bacterium,  Alloiococcus otitidis.  The present invention also relates to polynucleotide sequences encoding polypeptides of  Alloiococcus otitidis.  In particular, the invention relates to antigenic polypeptides encoded by the  Alloiococcus otitidis  open reading frames (ORFs), and to their use in immunogenic compositions, therapeutics, diagnostics and the like.

FIELD OF THE INVENTION

The present invention relates to the genomic sequence of Alloiococcus otitidis and polynucleotide sequences encoding polypeptides of the Gram-positive bacterium, Alloiococcus otitidis. The invention also relates to polynucleotides and polynucleotides encoding polypeptides, preferably antigenic polypeptides, encoded by the Alloiococcus otitidis open reading frames and the uses thereof.

BACKGROUND OF THE INVENTION

Otitis media, an inflammation of the middle ear, is the most frequent cause of visits to pediatricians' offices in the United States (Schappert, 1991). Approximately 80% of all children experience at least one episode of Otitis media by the age of three (Klein, 1994). There are three main types of otitis media: Acute otitis media (AOM), otorrhea, and otitis media with effusion (OME). Alloiococcus otitidis has only been associated with otitis media with effusion (OME), but this may be due to the difficulty of its detection by standard bacterial culturing methods. Its detection in the effusions is likely due to the fact that the effusions are normally sterile and few or no competing bacterial species are isolated from them. Without the interference of a faster growing nasophryngeal species, the culture plates are incubated for the longer duration needed to detect Alloiococcus otitidis colonies.

Three other bacterial species are commonly isolated from middle ear effusions. These are nontypable Haemophilus influenzae, Moraxella catarrhalis, and Streptococcus pneumoniae. One or more of these species have been found in one study to be associated with about 77% of all cases of OME using a PCR detection method (Post, 2000). This study did not include assaying for Alloiococcus otitidis, so a portion of the unaccounted cases may be due to this organism.

The bacterium Alloiococcus otitidis was first isolated from the middle ear fluids of 10 children in the Buffalo, N.Y. area with persistent OME and characterized as a large catalase negative, Gram-positive cocci that tend to occur in clumps, often in tetrads. It is slow growing and requires 2 to 5 days at 37° C. before colonies are seen on sheep blood agar plates (Table 1). The bacterium was named Alloiococcus otitis by Aguirre and Collins (1992), who showed that it was different from other known Gram-positive species based on its 16S rRNA sequence. Recently the bacterium's name has been changed from Alloiococcus otitis to Alloiococcus otitidis (Hendolin, et al. Pediatr. Infect. Dis. J. 18:860 (1999), Hendolin et al. J. Clin. Microbiol. 38:125 (2000)).

Several studies of the epidemiology Alloiococcus otitidis indicate it is associated with otitis media with effusion. These are summarized in Table 1. These studies have been carried out using both culture and PCR techniques. The number of cases detected by culture, as might be expected from the fastidious growth requirements of the bacterium, was less than the number detected by PCR. Assuming that the bacterium is detected more accurately by the PCR method, the bacterium is detected in between 10 and 50% of patients with OME. This frequency suggests that this organism represents a significant public health problem. Consequently, there is a need for immunogenic compositions to prevent symptoms caused by Alloiococcus otitidis infections. There is also a need for compositions for diagnosing Alloiococcus otitidis infections. TABLE 1 SUMMARY OF STUDIES INDICATING AN ASSOCIATION OF ALLOIOCOCCUS OTITIDIS WITH OTITIS MEDIA WITH EFFUSION (OME). % Detected N^(a) Method Reference 8 200 Culture Faden & Dryja, J. Clin. Microbiol. 27: 2488 (1989) 3 100 Culture Sih et al., ICAAC (1992) 20 25 PCR Hendolin et al., J. Clin. Microbiol. 35: 2854 (1997) 50 12 PCR Beswick, et al. Lancet 345: 386 (1999) 42 67 PCR Hendolin, et al. Pediatr. Infect. Dis. J. 18: 860 (1999) 10 49 PCR Hendolin et al. J. Clin. Microbiol. 38: 125 (2000) ^(a)Number of persons in study.

SUMMARY OF THE INVENTION

The present invention broadly relates to Alloiococcus otitidis genomic sequence. Particularly, the invention relates to newly identified polynucleotide open reading frames (ORFs) comprised within the genomic nucleotide sequence of Alloiococcus otitidis, and to polypeptides encoded by the ORFs. More particularly, the ORFs encode polypeptides that are surface localized, secreted, or exposed on Alloiococcus otitidis.

Thus, in certain aspects, the invention relates to Alloiococcus otitidis ORFs that encode Alloiococcus otitidis polypeptides. In preferred embodiments, these Alloiococcus otitidis polypeptides are antigenic polypeptides. As defined hereinafter, an Alloiococcus otitidis antigenic polypeptide, antigen or immunogen, is an Alloiococcus otitidis polypeptide that is immunoreactive with an antibody or an Alloiococcus otitidis polypeptide that elicits an immune response. In other embodiments, the invention relates to the polynucleotides encoding these antigenic polypeptides. In other aspects, the invention relates to vectors comprising Alloiococcus otitidis ORFs and cells or animals transformed with these vectors. The invention relates also to methods of detecting these nucleic acids or polypeptides and kits for diagnosing Alloiococcus otitidis infection. The invention further relates to pharmaceutical compositions, in particular immunogenic compositions, for the prevention and/or treatment of bacterial infection, in particular Alloiococcus otitidis.

In a preferred embodiment, the immunogenic compositions are used for the treatment or prevention of non-systemic diseases, particularly of the Otitis media, which are induced or worsened by Alloiococcus otitidis.

In particular embodiments, the invention relates to an isolated polynucleotide of an Alloiococcus otitidis genomic sequence, wherein the polynucleotide comprises a nucleotide sequence having at least about 70% identity to a nucleotide sequence chosen from one of odd numbered sequences set out in SEQ ID NO: 1 through 6649, a degenerate variant thereof, or a fragment thereof. As defined hereinafter, a “degenerate variant” is defined as a polynucleotide that differs from the nucleotide sequence shown in SEQ ID NO:1 through SEQ ID NO:6649 (and fragments thereof) due to degeneracy of the genetic code, but still encodes the same Alloiococcus otitidis polypeptide (i.e., SEQ ID NO:2 through SEQ ID NO:6650) as that encoded by the nucleotide sequence shown in SEQ ID NO:1 through SEQ ID NO:6649.

In other embodiments, the polynucleotide is a complement to a nucleotide sequence chosen from one of the odd numbered sequences set out in SEQ ID NO: 1 through SEQ ID NO: 6649, a degenerate variant thereof, or a fragment thereof. In yet other embodiments, the polynucleotide is selected from the group consisting of genomic DNA, cDNA and RNA or may further comprise heterologous nucleotides.

In another embodiment, the invention comprises an isolated polynucleotide that hybridizes to a nucleotide sequence chosen from one of odd numbered sequences set out in SEQ ID NO: 1 through SEQ ID NO: 6649, a complement hereof, a degenerate variant thereof, or a fragment thereof, under high stringency hybridization conditions. In yet other embodiments, the polynucleotide hybridizes under intermediate stringency hybridization conditions.

In a preferred embodiment, an isolated polynucleotide of a an Alloiococcus otitidis genomic sequence comprises a nucleotide sequence chosen from one of odd numbered sequences set out in SEQ ID NO: 1 through SEQ ID NO: 6649, a fragment thereof, or a degenerate variant thereof, and encodes a polypeptide, a biological equivalent thereof, or a fragment thereof, selected from the group consisting of (a) an Alloiococcus otitidis polypeptide predicted by SignaIP algorithm analysis as having met all four criteria set out in the SignaIP algorithm for a polypeptide having a signal peptide and a subset of these are predicted by HMM SignaIP algorithm analysis as having a signal peptide; (b) an Alloiococcus otitidis polypeptide predicted by SignaIP algorithm analysis as having met three of the four criteria set out in the SignaIP algorithm for a polypeptide having a signal peptide and a subset of these predicted by HMM SignaIP algorithm analysis as having a signal peptide; (c) an Alloiococcus otitidis polypeptide predicted by HMM SignaIP algorithm analysis as having a signal peptide; (d) an Alloiococcus otitidis polypeptide predicted by HMM SignaIP algorithm analysis as being a non-secretory protein; (e) an Alloiococcus otitidis polypeptide identified by Pfam analysis; (f) an Alloiococcus otitidis polypeptide identified by BlastP analysis as being secreted, surface exposed, vaccine candidate; (g) an Alloiococcus otitidis polypeptide identified using proteomics methodology as sharing homology with putative surface exposed proteins of Streptococcus pneumoniae; (h) an Alloiococcus otitidis polypeptide having a LPXTG motif, wherein the polypeptide is covalently attached to the peptidoglycan layer; (i) an Alloiococcus otitidis lipoprotein; (j) an Alloiococcus otitidis polypeptide non-covalently associated with the peptidoglycan layer; (k) an Alloiococcus otitidis polypeptide having an RGDX motif wherein X is not a proline residue; (I) an Alloiococcus otitidis polypeptide predicted by BlastP as being involved in capsule biosynthesis and transport; (m) an Alloiococcus otitidis polypeptide identified by BlastP as being localized within the capsule loci of the Alloiococcus otitidis genome; (n) an Alloiococcus otitidis polypeptide predicted by BlastP as being associated with sporulation; (o) an Alloiococcus otitidis polypeptide encoded by unique ORFs identified by BlastP analysis as having a BlastP ‘E Value’ of >e⁻¹⁰; (p) an Alloiococcus otitidis polypeptide identified by Glimmer™ ORF finder program; (q) an Alloiococcus otitidis polypeptide identified by GeneMark™ ORF finder program; (r) an Alloiococcus otitidis polypeptide identified by Applicants' assignee's ORF finder program that searches for an ATG, GTG or TTG Start codon between a Stop-Stop ORF; and (s) an Alloiococcus otitidis polypeptide identified by Applicants' assignee's ORF finder program that searches for a transmembrane domain between two Stop codons and a Start codon immediately upstream of this transmembrane region.

In one aspect of this embodiment, the polynucleotide is a complement to a nucleotide sequence selected from one of odd numbered sequences set out in SEQ ID NO: 1 and SEQ ID NO: 6649, a degenerate variant thereof, or a fragment thereof. In yet other aspects of this embodiment, the polynucleotide is selected from the group consisting of DNA, chromosomal DNA, cDNA and RNA or may further comprise heterologous nucleotides. In another aspect of the invention, the polynucleotide encodes a fusion polypeptide.

In a preferred embodiment, the invention comprises an isolated polynucleotide of the Alloiococcus otitidis genomic sequence encoding a polypeptide, which is predicted by SignaIP algorithm analysis as having met all four criteria set out in the SignaIP algorithm for a polypeptide having a signal peptide, and the polynucleotide is selected from one of Seq. ID No. 89, Seq. ID No. 127, Seq. ID No.131, Seq. ID No.133, Seq. ID No. 161, Seq. ID No.163, Seq. ID No. 213, Seq. ID No. 215, Seq. ID No. 225, Seq. ID No. 249, Seq. ID No. 251, Seq. ID No. 287, Seq. ID No. 289, Seq. ID No. 369, Seq. ID No. 371, Seq. ID No. 375, Seq. ID No. 377, Seq. ID No. 497, Seq. ID No. 503, Seq. ID No. 505, Seq. ID No. 527, Seq. ID No. 549, Seq. ID No. 575, Seq. ID No. 617, Seq. ID No. 657, Seq. ID No. 659, Seq. ID No. 661, Seq. ID No. 675, Seq. ID No. 715, Seq. ID No. 717, Seq. ID No. 745, Seq. ID No. 747, Seq. ID No. 755, Seq. ID No. 757, Seq. ID No. 759, Seq. ID No. 761, Seq. ID No. 773, Seq. ID No. 807, Seq. ID No. 967, Seq. ID No. 973, Seq. ID No. 975, Seq. ID No. 1013, Seq. ID No. 1025, Seq. ID No. 1027, Seq. ID No. 1039, Seq. ID No. 1075, Seq. ID No. 1089, Seq. ID No. 1195, Seq. ID No. 1197, Seq. ID No. 1207, Seq. ID No. 1239, Seq. ID No. 1243, Seq. ID No. 1245, Seq. ID No. 1269, Seq. ID No. 1315, Seq. ID No. 1317, Seq. ID No. 1331, Seq. ID No. 1365, Seq. ID No. 1367, Seq. ID No. 1369, Seq. ID No. 1445, Seq. ID No. 1447, Seq. ID No. 1513, Seq. ID No. 1517, Seq. ID No. 1545, Seq. ID No. 1549, Seq. ID No. 1561, Seq. ID No. 1569, Seq. ID No. 1571, Seq. ID No. 1585, Seq. ID No. 1643, Seq. ID No. 1653, Seq. ID No. 1661, Seq. ID No. 1663, Seq. ID No. 1707, Seq. ID No. 1733, Seq. ID No. 1737, Seq. ID No. 1755, Seq. ID No. 1765, Seq. ID No. 1767, Seq. ID No. 1775, Seq. ID No. 1791, Seq. ID No. 1805, Seq. ID No. 1875, Seq. ID No. 1969, Seq. ID No. 1981, Seq. ID No. 2053, Seq. ID No. 2055, Seq. ID No. 2087, Seq. ID No. 2089, Seq. ID No. 2091, Seq. ID No. 2105, Seq. ID No. 2115, Seq. ID No. 2149, Seq. ID No. 2151, Seq. ID No. 2159, Seq. ID No. 2177, Seq. ID No. 2277, Seq. ID No. 2293, Seq. ID No. 2321, Seq. ID No. 2347, Seq. ID No. 2351, Seq. ID No. 2353, Seq. ID No. 2365, Seq. ID No. 2395, Seq. ID No. 2421, Seq. ID No. 2425, Seq. ID No. 2427, Seq. ID No. 2429, Seq. ID No. 2449, Seq. ID No. 2459, Seq. ID No. 2525, Seq. ID No. 2531, Seq. ID No. 2607, Seq. ID No. 2651, Seq. ID No. 2679, Seq. ID No. 2693, Seq. ID No. 2699, Seq. ID No. 2703, Seq. ID No. 2753, Seq. ID No. 2785, Seq. ID No. 2813, Seq. ID No. 2829, Seq. ID No. 2835, Seq. ID No. 2841, Seq. ID No. 2879, Seq. ID No. 2881, Seq. ID No. 2935, Seq. ID No. 2937, Seq. ID No. 2949, Seq. ID No. 2965, Seq. ID No. 2967, Seq. ID No. 2973, Seq. ID No. 3007, Seq. ID No. 3009, Seq. ID No. 3011, Seq. ID No. 3029, Seq. ID No. 3031, Seq. ID No. 3109, Seq. ID No. 3111, Seq. ID No. 3219, Seq. ID No. 3223, Seq. ID No. 3273, Seq. ID No. 3297, Seq. ID No. 3331, Seq. ID No. 3335, Seq. ID No. 3341, Seq. ID No. 3349, Seq. ID No. 3353, Seq. ID No. 3355, Seq. ID No. 3377, Seq. ID No. 3391, Seq. ID No. 3425, Seq. ID No. 3449, Seq. ID No. 3493, Seq. ID No. 3573, Seq. ID No. 3611, Seq. ID No. 3619, Seq. ID No. 3689, Seq. ID No. 3753, Seq. ID No. 3755, Seq. ID No. 3765, Seq. ID No. 3781, Seq. ID No. 3783, Seq. ID No. 3851, Seq. ID No. 3903, Seq. ID No. 4005, Seq. ID No. 4007, Seq. ID No. 4027, Seq. ID No. 4073, Seq. ID No. 4137, Seq. ID No. 4141, Seq. ID No. 4143, Seq. ID No. 4145, Seq. ID No. 4225, Seq. ID No. 4343, Seq. ID No. 4385, Seq. ID No. 4399, Seq. ID No. 4469, Seq. ID No. 4483, Seq. ID No. 4493, Seq. ID No. 4495, Seq. ID No. 4533, Seq. ID No. 4699, Seq. ID No. 4709, Seq. ID No. 4711, Seq. ID No. 4735, Seq. ID No. 4827, Seq. ID No. 4871, Seq. ID No. 4873, Seq. ID No. 4879, Seq. ID No. 4921, Seq. ID No. 4981, Seq. ID No. 5115, Seq. ID No. 5267, Seq. ID No. 5341, Seq. ID No. 5387, Seq. ID No. 5465, Seq. ID No. 5467, Seq. ID No. 5479, Seq. ID No. 5497, Seq. ID No. 5513, Seq. ID No. 5543, Seq. ID No. 5545, Seq. ID No. 5567, Seq. ID No. 5587, Seq. ID No. 5589, Seq. ID No. 5591, Seq. ID No. 5611, Seq. ID No. 5621, Seq. ID No. 5641, Seq. ID No. 5681, Seq. ID No. 5719, Seq. ID No. 5771, Seq. ID No. 5783, Seq. ID No. 5895, Seq. ID No. 5899, Seq. ID No. 5901, Seq. ID No. 5927, Seq. ID No. 5929, Seq. ID No. 5939, Seq. ID No. 5987, Seq. ID No. 6013, Seq. ID No. 6087, Seq. ID No. 6089, Seq. ID No. 6091, Seq. ID No. 6093, Seq. ID No. 6095, Seq. ID No. 6103, Seq. ID No. 6169, Seq. ID No. 6185, Seq. ID No. 6187, Seq. ID No. 6195, Seq. ID No. 6197, Seq. ID No. 6203, Seq. ID No. 6205, Seq. ID No. 6221, Seq. ID No. 6223, Seq. ID No. 6229, Seq. ID No. 6291, Seq. ID No. 6415, Seq. ID No. 6417, Seq. ID No. 6473, Seq. ID No. 6507, Seq. ID No. 6543, Seq. ID No. 6595, Seq. ID No. 6597, Seq. ID No. 6599, Seq. ID No. 6601, and Seq. ID No. 6603.

In yet another preferred embodiment, the invention comprises an isolated polynucleotide of the Alloiococcus otitidis genomic sequence encoding a polypeptide which is predicted by SignaIP algorithm analysis as having met three of the four criteria set out in the SignaIP algorithm for a polypeptide having a signal peptide and which is predicted by HMM Signal P algorithm analysis as having a signal peptide, and the polynucleotide is selected from one of Seq. ID No. 7, Seq. ID No. 11, Seq. ID No. 23, Seq. ID No. 45, Seq. ID No. 47, Seq. ID No. 53, Seq. ID No. 59, Seq. ID No. 65, Seq. ID No. 67, Seq. ID No. 87, Seq. ID No. 91, Seq. ID No. 139, Seq. ID No. 151, Seq. ID No. 159, Seq. ID No. 165, Seq. ID No. 169, Seq. ID No. 185, Seq. ID No. 211, Seq. ID No. 217, Seq. ID No. 235, Seq. ID No. 237, Seq. ID No. 239, Seq. ID No. 271, Seq. ID No. 285, Seq. ID No. 291, Seq. ID No. 327, Seq. ID No. 349, Seq. ID No. 385, Seq. ID No. 387, Seq. ID No. 407, Seq. ID No. 427, Seq. ID No. 431, Seq. ID No. 455, Seq. ID No. 457, Seq. ID No. 495, Seq. ID No. 499, Seq. ID No. 511, Seq. ID No. 513, Seq. ID No. 515, Seq. ID No. 525, Seq. ID No. 545, Seq. ID No. 547, Seq. ID No. 557, Seq. ID No. 569, Seq. ID No. 589, Seq. ID No. 591, Seq. ID No. 593, Seq. ID No. 595, Seq. ID No. 609, Seq. ID No. 637, Seq. ID No. 639, Seq. ID No. 641, Seq. ID No. 653, Seq. ID No. 669, Seq. ID No. 679, Seq. ID No. 719, Seq. ID No. 723, Seq. ID No. 739, Seq. ID No. 749, Seq. ID No. 751, Seq. ID No. 763, Seq. ID No. 765, Seq. ID No. 769, Seq. ID No. 777, Seq. ID No. 779, Seq. ID No. 781, Seq. ID No. 819, Seq. ID No. 895, Seq. ID No. 903, Seq. ID No. 905, Seq. ID No. 909, Seq. ID No. 935, Seq. ID No. 937, Seq. ID No. 951, Seq. ID No. 955, Seq. ID No. 979, Seq. ID No. 981, Seq. ID No. 983, Seq. ID No. 985, Seq. ID No. 1005, Seq. ID No. 1007, Seq. ID No. 1009, Seq. ID No. 1015, Seq. ID No. 1019, Seq. ID No. 1029, Seq. ID No. 1031, Seq. ID No. 1047, Seq. ID No. 1091, Seq. ID No. 1111, Seq. ID No. 1137, Seq. ID No. 1151, Seq. ID No. 1153, Seq. ID No. 1169, Seq. ID No. 1173, Seq. ID No. 1183, Seq. ID No. 1191, Seq. ID No. 1193, Seq. ID No. 1213, Seq. ID No. 1223, Seq. ID No. 1229, Seq. ID No. 1247, Seq. ID No. 1259, Seq. ID No. 1283, Seq. ID No. 1307, Seq. ID No. 1319, Seq. ID No. 1321, Seq. ID No. 1327, Seq. ID No. 1341, Seq. ID No. 1343, Seq. ID No. 1347, Seq. ID No. 1389, Seq. ID No. 1401, Seq. ID No. 1429, Seq. ID No. 1479, Seq. ID No. 1551, Seq. ID No. 1559, Seq. ID No. 1579, Seq. ID No. 1587, Seq. ID No. 1621, Seq. ID No. 1627, Seq. ID No. 1633, Seq. ID No. 1645, Seq. ID No. 1647, Seq. ID No. 1649, Seq. ID No. 1655, Seq. ID No. 1665, Seq. ID No. 1667, Seq. ID No. 1671, Seq. ID No. 1677, Seq. ID No. 1679, Seq. ID No. 1681, Seq. ID No. 1695, Seq. ID No. 1703, Seq. ID No. 1705, Seq. ID No. 1731, Seq. ID No. 1753, Seq. ID No. 1759, Seq. ID No. 1763, Seq. ID No. 1787, Seq. ID No. 1797, Seq. ID No. 1821, Seq. ID No. 1823, Seq. ID No. 1833, Seq. ID No. 1839, Seq. ID No. 1841, Seq. ID No. 1843, Seq. ID No. 1893, Seq. ID No. 1917, Seq. ID No. 1919, Seq. ID No. 1971, Seq. ID No. 1991, Seq. ID No. 2013, Seq. ID No. 2015, Seq. ID No. 2017, Seq. ID No. 2019, Seq. ID No. 2033, Seq. ID No. 2035, Seq. ID No. 2049, Seq. ID No. 2081, Seq. ID No. 2083, Seq. ID No. 2085, Seq. ID No. 2111, Seq. ID No. 2113, Seq. ID No. 2123, Seq. ID No. 2125, Seq. ID No. 2127, Seq. ID No. 2131, Seq. ID No. 2133, Seq. ID No. 2153, Seq. ID No. 2161, Seq. ID No. 2171, Seq. ID No. 2175, Seq. ID No. 2179, Seq. ID No. 2187, Seq. ID No. 2201; Seq. ID No. 2203, Seq. ID No. 2221, Seq. ID No. 2237, Seq. ID No. 2249, Seq. ID No. 2251, Seq. ID No. 2255, Seq. ID No. 2261, Seq. ID No. 2263, Seq. ID No. 2271, Seq. ID No. 2279, Seq. ID No. 2283, Seq. ID No. 2285, Seq. ID No. 2289, Seq. ID No. 2295, Seq. ID No. 2305, Seq. ID No. 2307, Seq. ID No. 2317, Seq. ID No. 2319, Seq. ID No. 2323, Seq. ID No. 2325, Seq. ID No. 2343, Seq. ID No. 2349, Seq. ID No. 2385, Seq. ID No. 2393, Seq. ID No. 2423, Seq. ID No. 2453, Seq. ID No. 2491, Seq. ID No. 2497, Seq. ID No. 2499, Seq. ID No. 2507, Seq. ID No. 2515, Seq. ID No. 2517, Seq. ID No. 2521, Seq. ID No. 2523, Seq. ID No. 2527, Seq. ID No. 2533, Seq. ID No. 2535, Seq. ID No. 2541, Seq. ID No. 2543, Seq. ID No. 2547, Seq. ID No. 2549, Seq. ID No. 2557, Seq. ID No. 2573, Seq. ID No. 2583, Seq. ID No. 2601, Seq. ID No. 2603, Seq. ID No. 2621, Seq. ID No. 2653, Seq. ID No. 2681, Seq. ID No. 2691, Seq. ID No. 2701, Seq. ID No. 2733, Seq. ID No. 2739, Seq. ID No. 2801, Seq. ID No. 2807, Seq. ID No. 2815, Seq. ID No. 2819, Seq. ID No. 2821, Seq. ID No. 2823, Seq. ID No. 2833, Seq. ID No. 2837, Seq. ID No. 2839, Seq. ID No. 2845, Seq. ID No. 2853, Seq. ID No. 2861, Seq. ID No. 2865, Seq. ID No. 2873, Seq. ID No. 2875, Seq. ID No. 2877, Seq. ID No. 2883, Seq. ID No. 2895, Seq. ID No. 2905, Seq. ID No. 2939, Seq. ID No. 2941, Seq. ID No. 2947, Seq. ID No. 2981, Seq. ID No. 2983, Seq. ID No. 2987, Seq. ID No. 2991, Seq. ID No. 2995, Seq. ID No. 3001, Seq. ID No. 3005, Seq. ID No. 3021, Seq. ID No. 3025, Seq. ID No. 3043, Seq. ID No. 3045, Seq. ID No. 3073, Seq. ID No. 3075, Seq. ID No. 3155, Seq. ID No. 3163, Seq. ID No. 3165, Seq. ID No. 3167, Seq. ID No. 3183, Seq. ID No. 3213, Seq. ID No. 3215, Seq. ID No. 3235, Seq. ID No. 3245, Seq. ID No. 3261, Seq. ID No. 3263, Seq. ID No. 3265, Seq. ID No. 3269, Seq. ID No. 3271, Seq. ID No. 3275, Seq. ID No. 3277, Seq. ID No. 3317, Seq. ID No. 3325, Seq. ID No. 3337, Seq. ID No. 3351, Seq. ID No. 3389, Seq. ID No. 3405, Seq. ID No. 3419, Seq. ID No. 3421, Seq. ID No. 3423, Seq. ID No. 3451, Seq. ID No. 3453, Seq. ID No. 3455, Seq. ID No. 3491, Seq. ID No. 3495, Seq. ID No. 3503, Seq. ID No. 3505, Seq. ID No. 3517, Seq. ID No. 3519, Seq. ID No. 3545, Seq. ID No. 3547, Seq. ID No. 3571, Seq. ID No. 3593, Seq. ID No. 3617, Seq. ID No. 3621, Seq. ID No. 3629, Seq. ID No. 3663, Seq. ID No. 3701, Seq. ID No. 3703, Seq. ID No. 3723, Seq. ID No. 3737, Seq. ID No. 3741, Seq. ID No. 3745, Seq. ID No. 3747, Seq. ID No. 3759, Seq. ID No. 3763, Seq. ID No. 3767, Seq. ID No. 3769, Seq. ID No. 3771, Seq. ID No. 3785, Seq. ID No. 3793, Seq. ID No. 3813, Seq. ID No. 3837, Seq. ID No. 3839, Seq. ID No. 3861, Seq. ID No. 3865, Seq. ID No. 3889, Seq. ID No. 3891, Seq. ID No. 3895, Seq. ID No. 3915, Seq. ID No. 3923, Seq. ID No. 3925, Seq. ID No. 3929, Seq. ID No. 3965, Seq. ID No. 3975, Seq. ID No. 3979, Seq. ID No. 3995, Seq. ID No. 3997, Seq. ID No. 4009, Seq. ID No. 4039, Seq. ID No. 4041, Seq. ID No. 4061, Seq. ID No. 4079, Seq. ID No. 4081, Seq. ID No. 4111, Seq. ID No. 4113, Seq. ID No. 4135, Seq. ID No. 4139, Seq. ID No. 4155, Seq. ID No. 4181, Seq. ID No. 4203, Seq. ID No. 4221, Seq. ID No. 4247, Seq. ID No. 4253, Seq. ID No. 4257, Seq. ID No. 4259, Seq. ID No. 4261, Seq. ID No. 4263, Seq. ID No. 4269, Seq. ID No. 4311, Seq. ID No. 4379, Seq. ID No. 4389, Seq. ID No. 4391, Seq. ID No. 4471, Seq. ID No. 4473, Seq. ID No. 4481, Seq. ID No. 4525, Seq. ID No. 4551, Seq. ID No. 4561, Seq. ID No. 4573, Seq. ID No. 4617, Seq. ID No. 4639, Seq. ID No. 4659, Seq. ID No. 4681, Seq. ID No. 4701, Seq. ID No. 4705, Seq. ID No. 4713, Seq. ID No. 4717, Seq. ID No. 4721, Seq. ID No. 4737, Seq. ID No. 4741, Seq. ID No. 4813, Seq. ID No. 4817, Seq. ID No. 4819, Seq. ID No. 4829, Seq. ID No. 4831, Seq. ID No. 4851, Seq. ID No. 4869, Seq. ID No. 4875, Seq. ID No. 4913, Seq. ID No. 4919, Seq. ID No. 4929, Seq. ID No. 4931, Seq. ID No. 4983, Seq. ID No. 4993, Seq. ID No. 5011, Seq. ID No. 5023, Seq. ID No. 5031, Seq. ID No. 5033, Seq. ID No. 5035, Seq. ID No. 5043, Seq. ID No. 5061, Seq. ID No. 5063, Seq. ID No. 5069, Seq. ID No. 5103, Seq. ID No. 5121, Seq. ID No. 5123, Seq. ID No. 5131, Seq. ID No. 5133, Seq. ID No. 5135, Seq. ID No. 5137, Seq. ID No. 5139, Seq. ID No. 5141, Seq. ID No. 5151, Seq. ID No. 5159, Seq. ID No. 5161, Seq. ID No. 5165, Seq. ID No. 5167, Seq. ID No. 5175, Seq. ID No. 5177, Seq. ID No. 5205, Seq. ID No. 5207, Seq. ID No. 5211, Seq. ID No. 5215, Seq. ID No. 5219, Seq. ID No. 5223, Seq. ID No. 5285, Seq. ID No. 5287, Seq. ID No. 5329, Seq. ID No. 5331, Seq. ID No. 5377, Seq. ID No. 5379, Seq. ID No. 5381, Seq. ID No. 5385, Seq. ID No. 5405, Seq. ID No. 5407, Seq. ID No. 5453, Seq. ID No. 5459, Seq. ID No. 5461, Seq. ID No. 5463, Seq. ID No. 5481, Seq. ID No. 5509, Seq. ID No. 5529, Seq. ID No. 5531, Seq. ID No. 5557, Seq. ID No. 5569, Seq. ID No. 5577, Seq. ID No. 5623, Seq. ID No. 5625, Seq. ID No. 5643, Seq. ID No. 5659, Seq. ID No. 5661, Seq. ID No. 5683, Seq. ID No. 5685, Seq. ID No. 5709, Seq. ID No. 5711, Seq. ID No. 5733, Seq. ID No. 5739, Seq. ID No. 5765, Seq. ID No. 5797, Seq. ID No. 5827, Seq. ID No. 5889, Seq. ID No. 5893, Seq. ID No. 5905, Seq. ID No. 5909, Seq. ID No. 5911, Seq. ID No. 5923, Seq. ID No. 5963, Seq. ID No. 5965, Seq. ID No. 6025, Seq. ID No. 6027, Seq. ID No. 6031, Seq. ID No. 6043, Seq. ID No. 6045, Seq. ID No. 6047, Seq. ID No. 6053, Seq. ID No. 6059, Seq. ID No. 6109, Seq. ID No. 6111, Seq. ID No. 6115, Seq. ID No. 6117, Seq. ID No. 6127, Seq. ID No. 6131, Seq. ID No. 6135, Seq. ID No. 6137, Seq. ID No. 6161, Seq. ID No. 6165, Seq. ID No. 6183, Seq. ID No. 6189, Seq. ID No. 6191, Seq. ID No. 6193, Seq. ID No. 6207, Seq. ID No. 6209, Seq. ID No. 6217, Seq. ID No. 6225, Seq. ID No. 6235, Seq. ID No. 6243, Seq. ID No. 6249, Seq. ID No. 6253, Seq. ID No. 6259, Seq. ID No. 6265, Seq. ID No. 6267, Seq. ID No. 6275, Seq. ID No. 6283, Seq. ID No. 6285, Seq. ID No. 6303, Seq. ID No. 6325, Seq. ID No. 6327, Seq. ID No. 6363, Seq. ID No. 6365, Seq. ID No. 6367, Seq. ID No. 6385, Seq. ID No. 6425, Seq. ID No. 6427, Seq. ID No. 6429, Seq. ID No. 6431, Seq. ID No. 6453, Seq. ID No. 6465, Seq. ID No. 6469, Seq. ID No. 6471, Seq. ID No. 6479, Seq. ID No. 6539, Seq. ID No. 6541, Seq. ID No. 6571, Seq. ID No. 6573, Seq. ID No. 6639, Seq. ID No. 6643, and Seq. ID No. 6645.

In yet another preferred embodiment, the invention comprises an isolated polynucleotide of the Alloiococcus otitidis genomic sequence encoding a polypeptide, which is predicted by HMM SignaIP algorithm analysis as having a signal peptide, and the polynucleotide is selected from one of Seq. ID No. 3, Seq. ID No. 7, Seq. ID No. 9, Seq. ID No. 19, Seq. ID No. 21, Seq. ID No. 31, Seq. ID No. 33, Seq. ID No. 45, Seq. ID No. 47, Seq. ID No. 49, Seq. ID No. 53, Seq. ID No. 65, Seq. ID No. 67, Seq. ID No. 85, Seq. ID No. 87, Seq. ID No. 105, Seq. ID No. 111, Seq. ID No. 123, Seq. ID No. 131, Seq. ID No. 133, Seq. ID No. 141, Seq. ID No. 159, Seq. ID No. 161, Seq. ID No. 163, Seq. ID No. 171, Seq. ID No. 191, Seq. ID No. 209, Seq. ID No. 211, Seq. ID No. 213, Seq. ID No. 215, Seq. ID No. 217, Seq. ID No. 225, Seq. ID No. 235, Seq. ID No. 237, Seq. ID No. 249, Seq. ID No. 251, Seq. ID No. 255, Seq. ID No. 257, Seq. ID No. 259, Seq. ID No. 271, Seq. ID No. 273, Seq. ID No. 277, Seq. ID No. 285, Seq. ID No. 287, Seq. ID No. 289, Seq. ID No. 327, Seq. ID No. 329, Seq. ID No. 357, Seq. ID No. 359, Seq. ID No. 373, Seq. ID No. 375, Seq. ID No. 393, Seq. ID No. 401, Seq. ID No. 403, Seq. ID No. 455, Seq. ID No. 457, Seq. ID No. 477, Seq. ID No. 487, Seq. ID No. 489, Seq. ID No. 491, Seq. ID No. 493, Seq. ID No. 495, Seq. ID No. 497, Seq. ID No. 499, Seq. ID No. 503, Seq. ID No. 505, Seq. ID No. 509, Seq. ID No. 511, Seq. ID No. 513, Seq. ID No. 515, Seq. ID No. 525, Seq. ID No. 527, Seq. ID No. 545, Seq. ID No. 547, Seq. ID No. 549, Seq. ID No. 557, Seq. ID No. 567, Seq. ID No. 569, Seq. ID No. 575, Seq. ID No. 577, Seq. ID No. 579, Seq. ID No. 591, Seq. ID No. 593, Seq. ID No. 599, Seq. ID No. 617, Seq. ID No. 637, Seq. ID No. 639, Seq. ID No. 641, Seq. ID No. 643, Seq. ID No. 645, Seq. ID No. 647, Seq. ID No. 653, Seq. ID No. 655, Seq. ID No. 657, Seq. ID No. 659, Seq. ID No. 661, Seq. ID No. 667, Seq. ID No. 669, Seq. ID No. 675, Seq. ID No. 677, Seq. ID No. 679, Seq. ID No. 715, Seq. ID No. 717, Seq. ID No. 719, Seq. ID No. 721, Seq. ID No. 723, Seq. ID No. 725, Seq. ID No. 745, Seq. ID No. 747, Seq. ID No. 749, Seq. ID No. 751, Seq. ID No. 755, Seq. ID No. 757, Seq. ID No. 759, Seq. ID No. 761, Seq. ID No. 763, Seq. ID No. 765, Seq. ID No. 769, Seq. ID No. 777, Seq. ID No. 779, Seq. ID No. 781, Seq. ID No. 807, Seq. ID No. 809, Seq. ID No. 819, Seq. ID No. 825, Seq. ID No. 863, Seq. ID No. 893, Seq. ID No. 901, Seq. ID No. 935, Seq. ID No. 937, Seq. ID No. 941, Seq. ID No. 943, Seq. ID No. 955, Seq. ID No. 957, Seq. ID No. 967, Seq. ID No. 979, Seq. ID No. 981, Seq. ID No. 983, Seq. ID No. 985, Seq. ID No. 1001, Seq. ID No. 1003, Seq. ID No. 1005, Seq. ID No. 1007, Seq. ID No. 1009, Seq. ID No. 1011, Seq. ID No. 1013, Seq. ID No. 1015, Seq. ID No. 1019, Seq. ID No. 1029, Seq. ID No. 1031, Seq. ID No. 1033, Seq. ID No. 1035, Seq. ID No. 1037, Seq. ID No. 1039, Seq. ID No. 1045, Seq. ID No. 1055, Seq. ID No. 1075, Seq. ID No. 1077, Seq. ID No. 1105, Seq. ID No. 1107, Seq. ID No. 1131, Seq. ID No. 1135, Seq. ID No. 1137, Seq. ID No. 1139, Seq. ID No. 1151, Seq. ID No. 1165, Seq. ID No. 1167, Seq. ID No. 1169, Seq. ID No. 1173, Seq. ID No. 1183, Seq. ID No. 1195, Seq. ID No. 1197, Seq. ID No. 1203, Seq. ID No. 1213, Seq. ID No. 1223, Seq. ID No. 1227, Seq. ID No. 1229, Seq. ID No. 1237, Seq. ID No. 1243, Seq. ID No. 1245, Seq. ID No. 1259, Seq. ID No. 1265, Seq. ID No. 1267, Seq. ID No. 1269, Seq. ID No. 1271, Seq. ID No. 1283, Seq. ID No. 1287, Seq. ID No. 1289, Seq. ID No. 1291, Seq. ID No. 1295, Seq. ID No. 1297, Seq. ID No. 1303, Seq. ID No. 1305, Seq. ID No. 1315, Seq. ID No. 1317, Seq. ID No. 1319, Seq. ID No. 1325, Seq. ID No. 1327, Seq. ID No. 1329, Seq. ID No. 1331, Seq. ID No. 1337, Seq. ID No. 1341, Seq. ID No. 1343, Seq. ID No. 1347, Seq. ID No. 1349, Seq. ID No. 1351, Seq. ID No. 1353, Seq. ID No. 1365, Seq. ID No. 1367, Seq. ID No. 1369, Seq. ID No. 1371, Seq. ID No. 1381, Seq. ID No. 1401, Seq. ID No. 1429, Seq. ID No. 1435, Seq. ID No. 1445, Seq. ID No. 1447, Seq. ID No. 1481, Seq. ID No. 1513, Seq. ID No. 1515, Seq. ID No. 1517, Seq. ID No. 1529, Seq. ID No. 1533, Seq. ID No. 1535, Seq. ID No. 1545, Seq. ID No. 1547, Seq. ID No. 1551, Seq. ID No. 1553, Seq. ID No. 1559, Seq. ID No. 1561, Seq. ID No. 1563, Seq. ID No. 1571, Seq. ID No. 1579, Seq. ID No. 1583, Seq. ID No. 1585, Seq. ID No. 1621, Seq. ID No. 1633, Seq. ID No. 1639, Seq. ID No. 1643, Seq. ID No. 1645, Seq. ID No. 1647, Seq. ID No. 1649, Seq. ID No. 1653, Seq. ID No. 1661, Seq. ID No. 1663, Seq. ID No. 1665, Seq. ID No. 1671, Seq. ID No. 1673, Seq. ID No. 1677, Seq. ID No. 1679, Seq. ID No. 1681, Seq. ID No. 1693, Seq. ID No. 1707, Seq. ID No. 1711, Seq. ID No. 1731, Seq. ID No. 1733, Seq. ID No. 1737, Seq. ID No. 1753, Seq. ID No. 1755, Seq. ID No. 1757, Seq. ID No. 1765, Seq. ID No. 1767, Seq. ID No. 1771, Seq. ID No. 1781, Seq. ID No. 1787, Seq. ID No. 1791, Seq. ID No. 1797, Seq. ID No. 1805, Seq. ID No. 1819, Seq. ID No. 1821, Seq. ID No. 1823, Seq. ID No. 1839, Seq. ID No. 1857, Seq. ID No. 1869, Seq. ID No. 1875, Seq. ID No. 1891, Seq. ID No. 1893, Seq. ID No. 1895, Seq. ID No. 1915, Seq. ID No. 1917, Seq. ID No. 1919, Seq. ID No. 1923, Seq. ID No. 1927, Seq. ID No. 1929, Seq. ID No. 1969, Seq. ID No. 1981, Seq. ID No. 1991, Seq. ID No. 1993, Seq. ID No. 2005, Seq. ID No. 2013, Seq. ID No. 2017, Seq. ID No. 2019, Seq. ID No. 2025, Seq. ID No. 2027, Seq. ID No. 2033, Seq. ID No. 2035, Seq. ID No. 2041, Seq. ID No. 2049, Seq. ID No. 2053, Seq. ID No. 2055, Seq. ID No. 2087, Seq. ID No. 2089, Seq. ID No. 2091, Seq. ID No. 2105, Seq. ID No. 2107, Seq. ID No. 2109, Seq. ID No. 2113, Seq. ID No. 2115, Seq. ID No. 2121, Seq. ID No. 2123, Seq. ID No. 2125, Seq. ID No. 2127, Seq. ID No. 2149, Seq. ID No. 2151, Seq. ID No. 2155, Seq. ID No. 2157, Seq. ID No. 2159, Seq. ID No. 2171, Seq. ID No. 2173, Seq. ID No. 2177, Seq. ID No. 2187, Seq. ID No. 2191, Seq. ID No. 2205, Seq. ID No. 2237, Seq. ID No. 2239, Seq. ID No. 2245, Seq. ID No. 2249, Seq. ID No. 2251, Seq. ID No. 2255, Seq. ID No. 2259, Seq. ID No. 2271, Seq. ID No. 2283, Seq. ID No. 2289, Seq. ID No. 2291, Seq. ID No. 2293, Seq. ID No. 2295, Seq. ID No. 2303, Seq. ID No. 2305, Seq. ID No. 2307, Seq. ID No. 2317, Seq. ID No. 2319, Seq. ID No. 2321, Seq. ID No. 2323, Seq. ID No. 2325, Seq. ID No. 2327, Seq. ID No. 2329, Seq. ID No. 2333, Seq. ID No. 2343, Seq. ID No. 2347, Seq. ID No. 2349, Seq. ID No. 2351, Seq. ID No. 2353, Seq. ID No. 2355, Seq. ID No. 2357, Seq. ID No. 2365, Seq. ID No. 2367, Seq. ID No. 2371, Seq. ID No. 2375, Seq. ID No. 2387, Seq. ID No. 2389, Seq. ID No. 2391, Seq. ID No. 2393, Seq. ID No. 2407, Seq. ID No. 2419, Seq. ID No. 2421, Seq. ID No. 2425, Seq. ID No. 2427, Seq. ID No. 2429, Seq. ID No. 2433, Seq. ID No. 2449, Seq. ID No. 2459, Seq. ID No. 2487, Seq. ID No. 2489, Seq. ID No. 2491, Seq. ID No. 2493, Seq. ID No. 2497, Seq. ID No. 2499, Seq. ID No. 2501, Seq. ID No. 2503, Seq. ID No. 2507, Seq. ID No. 2515, Seq. ID No. 2517, Seq. ID No. 2523, Seq. ID No. 2525, Seq. ID No. 2527, Seq. ID No. 2531, Seq. ID No. 2533, Seq. ID No. 2535, Seq. ID No. 2537, Seq. ID No. 2541, Seq. ID No. 2543, Seq. ID No. 2545, Seq. ID No. 2555, Seq. ID No. 2557, Seq. ID No. 2565, Seq. ID No. 2569, Seq. ID No. 2571, Seq. ID No. 2583, Seq. ID No. 2591, Seq. ID No. 2597, Seq. ID No. 2599, Seq. ID No. 2601, Seq. ID No. 2607, Seq. ID No. 2611, Seq. ID No. 2621, Seq. ID No. 2627, Seq. ID No. 2629, Seq. ID No. 2651, Seq. ID No. 2679, Seq. ID No. 2681, Seq. ID No. 2683, Seq. ID No. 2691, Seq. ID No. 2693, Seq. ID No. 2695, Seq. ID No. 2697, Seq. ID No. 2699, Seq. ID No. 2701, Seq. ID No. 2703, Seq. ID No. 2705, Seq. ID No. 2707, Seq. ID No. 2717, Seq. ID No. 2729, Seq. ID No. 2731, Seq. ID No. 2733, Seq. ID No. 2783, Seq. ID No. 2785, Seq. ID No. 2801, Seq. ID No. 2809, Seq. ID No. 2813, Seq. ID No. 2815, Seq. ID No. 2819, Seq. ID No. 2821, Seq. ID No. 2823, Seq. ID No. 2831, Seq. ID No. 2833, Seq. ID No. 2835, Seq. ID No. 2837, Seq. ID No. 2839, Seq. ID No. 2841, Seq. ID No. 2845, Seq. ID No. 2853, Seq. ID No. 2855, Seq. ID No. 2859, Seq. ID No. 2861, Seq. ID No. 2873, Seq. ID No. 2881, Seq. ID No. 2893, Seq. ID No. 2905, Seq. ID No. 2935, Seq. ID No. 2937, Seq. ID No. 2939, Seq. ID No. 2941, Seq. ID No. 2947, Seq. ID No. 2949, Seq. ID No. 2951, Seq. ID No. 2969, Seq. ID No. 2973, Seq. ID No. 2975, Seq. ID No. 2977, Seq. ID No. 2981, Seq. ID No. 2983, Seq. ID No. 2987, Seq. ID No. 2991, Seq. ID No. 2995, Seq. ID No. 2997, Seq. ID No. 3005, Seq. ID No. 3007, Seq. ID No. 3009, Seq. ID No. 3011, Seq. ID No. 3013, Seq. ID No. 3023, Seq. ID No. 3025, Seq. ID No. 3027, Seq. ID No. 3029, Seq. ID No. 3031, Seq. ID No. 3043, Seq. ID No. 3055, Seq. ID No. 3063, Seq. ID No. 3071, Seq. ID No. 3073, Seq. ID No. 3075, Seq. ID No. 3077, Seq. ID No. 3119, Seq. ID No. 3121, Seq. ID No. 3123, Seq. ID No. 3145, Seq. ID No. 3155, Seq. ID No. 3157, Seq. ID No. 3163, Seq. ID No. 3165, Seq. ID No. 3173, Seq. ID No. 3183, Seq. ID No. 3193, Seq. ID No. 3201, Seq. ID No. 3213, Seq. ID No. 3215, Seq. ID No. 3217, Seq. ID No. 3219, Seq. ID No. 3241, Seq. ID No. 3243, Seq. ID No. 3245, Seq. ID No. 3249, Seq. ID No. 3255, Seq. ID No. 3257, Seq. ID No. 3261, Seq. ID No. 3263, Seq. ID No. 3269, Seq. ID No. 3275, Seq. ID No. 3277, Seq. ID No. 3297, Seq. ID No. 3317, Seq. ID No. 3323, Seq. ID No. 3325, Seq. ID No. 3331, Seq. ID No. 3335, Seq. ID No. 3337, Seq. ID No. 3339, Seq. ID No. 3349, Seq. ID No. 3351, Seq. ID No. 3353, Seq. ID No. 3355, Seq. ID No. 3357, Seq. ID No. 3359, Seq. ID No. 3375, Seq. ID No. 3377, Seq. ID No. 3389, Seq. ID No. 3391, Seq. ID No. 3395, Seq. ID No. 3405, Seq. ID No. 3415, Seq. ID No. 3421, Seq. ID No. 3425, Seq. ID No. 3427, Seq. ID No. 3433, Seq. ID No. 3441, Seq. ID No. 3449, Seq. ID No. 3451, Seq. ID No. 3453, Seq. ID No. 3455, Seq. ID No. 3457, Seq. ID No. 3463, Seq. ID No. 3481, Seq. ID No. 3491, Seq. ID No. 3493, Seq. ID No. 3503, Seq. ID No. 3505, Seq. ID No. 3517, Seq. ID No. 3519, Seq. ID No. 3527, Seq. ID No. 3531, Seq. ID No. 3539, Seq. ID No. 3561, Seq. ID No. 3573, Seq. ID No. 3581, Seq. ID No. 3587, Seq. ID No. 3593, Seq. ID No. 3595, Seq. ID No. 3611, Seq. ID No. 3617, Seq. ID No. 3619, Seq. ID No. 3621, Seq. ID No. 3625, Seq. ID No. 3629, Seq. ID No. 3635, Seq. ID No. 3677, Seq ID No. 3679, Seq. ID No. 3689, Seq. ID No. 3717, Seq. ID No. 3723, Seq. ID No. 3727, Seq. ID No. 3741, Seq. ID No. 3745, Seq. ID No. 3753, Seq. ID No. 3755, Seq. ID No. 3757, Seq. ID No. 3761, Seq. ID No. 3763, Seq. ID No. 3765, Seq. ID No. 3781, Seq. ID No. 3783, Seq. ID No. 3793, Seq. ID No. 3799, Seq. ID No. 3807, Seq. ID No. 3813, Seq. ID No. 3815, Seq. ID No. 3817, Seq. ID No. 3837, Seq. ID No. 3839, Seq. ID No. 3849, Seq. ID No. 3851, Seq. ID No. 3853, Seq. ID No. 3859, Seq. ID No. 3861, Seq. ID No. 3863, Seq. ID No. 3865, Seq. ID No. 3879, Seq. ID No. 3889, Seq. ID No. 3891, Seq. ID No. 3895, Seq. ID No. 3903, Seq. ID No. 3915, Seq. ID No. 3923, Seq. ID No. 3925, Seq. ID No. 3959, Seq. ID No. 3963, Seq. ID No. 3973, Seq. ID No. 3975, Seq. ID No. 3993, Seq. ID No. 3995, Seq. ID No. 3997, Seq. ID No. 4005, Seq. ID No. 4007, Seq. ID No. 4009, Seq. ID No. 4025, Seq. ID No. 4027, Seq. ID No. 4039, Seq. ID No. 4041, Seq. ID No. 4043, Seq. ID No. 4045, Seq. ID No. 4047, Seq. ID No. 4049, Seq. ID No. 4061, Seq. ID No. 4071, Seq. ID No. 4073, Seq. ID No. 4079, Seq. ID No. 4081, Seq. ID No. 4083, Seq. ID No. 4101, Seq. ID No. 4103, Seq. ID No. 4111, Seq. ID No. 4133, Seq. ID No. 4135, Seq. ID No. 4137, Seq. ID No. 4139, Seq. ID No. 4141, Seq. ID No. 4143, Seq. ID No. 4145, Seq. ID No. 4151, Seq. ID No. 4153, Seq. ID No. 4181, Seq. ID No. 4221, Seq. ID No. 4223, Seq. ID No. 4225, Seq. ID No. 4227, Seq. ID No. 4231, Seq. ID No. 4233, Seq. ID No. 4241, Seq. ID No. 4247, Seq. ID No. 4253, Seq. ID No. 4257, Seq. ID No. 4259, Seq. ID No. 4261, Seq. ID No. 4263, Seq. ID No. 4265, Seq. ID No. 4269, Seq. ID No. 4275, Seq. ID No. 4285, Seq. ID No. 4287, Seq. ID No. 4297, Seq. ID No. 4307, Seq. ID No. 4311, Seq. ID No. 4313, Seq. ID No. 4343, Seq. ID No. 4389, Seq. ID No. 4391, Seq. ID No. 4399, Seq. ID No. 4403, Seq. ID No. 4437, Seq. ID No. 4439, Seq. ID No. 4441, Seq. ID No. 4469, Seq. ID No. 4473, Seq. ID No. 4481, Seq. ID No. 4483, Seq. ID No. 4485, Seq. ID No. 4493, Seq. ID No. 4495, Seq. ID No. 4497, Seq. ID No. 4513, Seq. ID No. 4515, Seq. ID No. 4527, Seq. ID No. 4529, Seq. ID No. 4533, Seq. ID No. 4587, Seq. ID No. 4589, Seq. ID No. 4639, Seq. ID No. 4641, Seq. ID No. 4643, Seq. ID No. 4659, Seq. ID No. 4681, Seq. ID No. 4687, Seq. ID No. 4695, Seq. ID No. 4705, Seq. ID No. 4707, Seq. ID No. 4709, Seq. ID No. 4711, Seq. ID No. 4715, Seq. ID No. 4717, Seq. ID No. 4737, Seq. ID No. 4759, Seq. ID No. 4813, Seq. ID No. 4827, Seq. ID No. 4853, Seq. ID No. 4863, Seq. ID No. 4869, Seq. ID No. 4871, Seq. ID No. 4873, Seq. ID No. 4875, Seq. ID No. 4919, Seq. ID No. 4921, Seq. ID No. 4923, Seq. ID No. 4929, Seq. ID No. 4931, Seq. ID No. 4949, Seq. ID No. 4951, Seq. ID No. 4975, Seq. ID No. 4987, Seq. ID No. 4999, Seq. ID No. 5013, Seq. ID No. 5031, Seq. ID No. 5061, Seq. ID No. 5063, Seq. ID No. 5069, Seq. ID No. 5085, Seq. ID No. 5103, Seq. ID No. 5115, Seq. ID No. 5123, Seq. ID No. 5125, Seq. ID No. 5129, Seq. ID No. 5131, Seq. ID No. 5133, Seq. ID No. 5135, Seq. ID No. 5137, Seq. ID No. 5139, Seq. ID No. 5141, Seq. ID No. 5159, Seq. ID No. 5165, Seq. ID No. 5175, Seq. ID No. 5197, Seq. ID No. 5199, Seq. ID No. 5205, Seq. ID No. 5207, Seq. ID No. 5213, Seq. ID No. 5219, Seq. ID No. 5223, Seq. ID No. 5267, Seq. ID No. 5273, Seq. ID No. 5275, Seq. ID No. 5277, Seq. ID No. 5279, Seq. ID No. 5281, Seq. ID No. 5285, Seq. ID No. 5327, Seq. ID No. 5329, Seq. ID No. 5331, Seq. ID No. 5341, Seq. ID No. 5377, Seq. ID No. 5379, Seq. ID No. 5385, Seq. ID No; 5387, Seq. ID No. 5405, Seq. ID No. 5413, Seq. ID No. 5415, Seq. ID No. 5433, Seq. ID No. 5453, Seq. ID No. 5459, Seq. ID No. 5461, Seq. ID No. 5463, Seq. ID No. 5465, Seq. ID No. 5491, Seq. ID No. 5497, Seq. ID No. 5509, Seq. ID No. 5513, Seq. ID No. 5515, Seq. ID No. 5517, Seq. ID No. 5525, Seq. ID No. 5529, Seq. ID No. 5531, Seq. ID No. 5533, Seq. ID No. 5543, Seq. ID No. 5545, Seq. ID No. 5569, Seq. ID No. 5587, Seq. ID No. 5589, Seq. ID No. 5591, Seq. ID No. 5593, Seq. ID No. 5595, Seq. ID No. 5597, Seq. ID No. 5609, Seq. ID No. 5611, Seq. ID No. 5621, Seq. ID No. 5623, Seq. ID No. 5625, Seq. ID No. 5633, Seq. ID No. 5637, Seq. ID No. 5639, Seq. ID No. 5641, Seq. ID No. 5643, Seq. ID No. 5649, Seq. ID No. 5659, Seq. ID No. 5667, Seq. ID No. 5681, Seq. ID No. 5683, Seq. ID No. 5685, Seq. ID No. 5687, Seq. ID No. 5689, Seq. ID No. 5699, Seq. ID No. 5703, Seq. ID No. 5705, Seq. ID No. 5709, Seq. ID No. 5711, Seq. ID No. 5719, Seq. ID No. 5729, Seq. ID No. 5733, Seq. ID No. 5735, Seq. ID No. 5739, Seq. ID No. 5763, Seq. ID No. 5765, Seq. ID No. 5767, Seq. ID No. 5771, Seq. ID No. 5783, Seq. ID No. 5785, Seq. ID No. 5791, Seq. ID No. 5797, Seq. ID No. 5829, Seq. ID No. 5879, Seq. ID No. 5883, Seq. ID No. 5885, Seq. ID No. 5889, Seq. ID No. 5893, Seq. ID No. 5895, Seq. ID No. 5899, Seq. ID No. 5901, Seq. ID No. 5905, Seq. ID No. 5909, Seq. ID No. 5921, Seq. ID No. 5923, Seq. ID No. 5927, Seq. ID No. 5929, Seq. ID No. 5939, Seq. ID No. 6023, Seq. ID No. 6025, Seq. ID No. 6027, Seq. ID No. 6043, Seq. ID No. 6047, Seq. ID No. 6053, Seq. ID No. 6059, Seq. ID No. 6063, Seq. ID No. 6067, Seq. ID No. 6087, Seq. ID No. 6089, Seq. ID No. 6091, Seq. ID No. 6095, Seq. ID No. 6103, Seq. ID No. 6107, Seq. ID No. 6109, Seq. ID No. 6111, Seq. ID No. 6115, Seq. ID No. 6117, Seq. ID No. 6135, Seq. ID No. 6137, Seq. ID No. 6159, Seq. ID No. 6161, Seq. ID No. 6163, Seq. ID No. 6165, Seq. ID No. 6169, Seq. ID No. 6183, Seq. ID No. 6185, Seq. ID No. 6187, Seq. ID No. 6189, Seq. ID No. 6191, Seq. ID No. 6197, Seq. ID No. 6203, Seq. ID No. 6205, Seq. ID No. 6209, Seq. ID No. 6217, Seq. ID No. 6221, Seq. ID No. 6223, Seq. ID No. 6225, Seq. ID No. 6227, Seq. ID No. 6229, Seq. ID No. 6235, Seq. ID No. 6237, Seq. ID No. 6241, Seq. ID No. 6243, Seq. ID No. 6245, Seq. ID No. 6249, Seq. ID No. 6253, Seq. ID No. 6259, Seq. ID No. 6263, Seq. ID No. 6265, Seq. ID No. 6267, Seq. ID No. 6273, Seq. ID No. 6275, Seq. ID No. 6283, Seq. ID No. 6285, Seq. ID No. 6289, Seq. ID No. 6301, Seq. ID No. 6303, Seq. ID No. 6325, Seq. ID No. 6327, Seq. ID No. 6363, Seq. ID No. 6365, Seq. ID No. 6377, Seq. ID No. 6381, Seq. ID No. 6383, Seq. ID No. 6415, Seq. ID No. 6425, Seq. ID No. 6427, Seq. ID No. 6429, Seq. ID No. 6431, Seq. ID No. 6473, Seq. ID No. 6479, Seq. ID No. 6497, Seq. ID No. 6517, Seq. ID No. 6541, Seq. ID No. 6543, Seq. ID No. 6555, Seq. ID No. 6557, Seq. ID No. 6571, Seq. ID No. 6573, Seq. ID No. 6581, Seq. ID No. 6593, Seq. ID No. 6595, Seq. ID No. 6597, Seq. ID No. 6599, Seq. ID No. 6601, Seq. ID No. 6603, Seq. ID No. 6631, Seq. ID No. 6637, Seq. ID No. 6639, Seq. ID No. 6643, Seq. ID No. 6645, and Seq. ID No. 6649.

In still yet another preferred embodiment, the invention comprises an isolated polynucleotide of the Alloiococcus otitidis genomic sequence encoding a polypeptide, which is predicted by HMM SignaIP algorithm analysis as being a non-secretory protein, and the polypeptide is selected from Seq. ID No. 1, Seq. ID No. 5, Seq. ID No. 11, Seq.

ID No. 13, Seq. ID No. 15, Seq. ID No. 17, Seq. ID No. 23, Seq. ID No. 25, Seq. ID No. 27, Seq. ID No. 29, Seq. ID No. 35, Seq. ID No. 37, Seq. ID No. 39, Seq. ID No. 41, Seq. ID No. 43, Seq. ID No. 51, Seq. ID No. 55, Seq. ID No. 57, Seq. ID No. 59, Seq. ID No. 61, Seq. ID No. 63, Seq. ID No. 69, Seq. ID No. 71, Seq. ID No. 73, Seq. ID No. 75, Seq. ID No. 77, Seq. ID No. 79, Seq. ID No. 81, Seq. ID No. 83, Seq. ID No. 89, Seq. ID No. 91, Seq. ID No. 93, Seq. ID No. 95, Seq. ID No. 97, Seq. ID No. 99, Seq. ID No. 101, Seq. ID No. 103, Seq. ID No. 107, Seq. ID No. 109, Seq. ID No. 113, Seq. ID No. 115, Seq. ID No. 117, Seq. ID No. 119, Seq. ID No. 121, Seq. ID No. 125, Seq. ID No. 127, Seq. ID No. 129, Seq. ID No. 135, Seq. ID No. 137, Seq. ID No. 139, Seq. ID No. 143, Seq. ID No. 145, Seq. ID No. 147, Seq. ID No. 149, Seq. ID No. 151, Seq. ID No. 153, Seq. ID No. 155, Seq. ID No. 157, Seq. ID No. 165, Seq. ID No. 167, Seq. ID No. 169, Seq. ID No. 173, Seq. ID No. 175, Seq. ID No. 177, Seq. ID No. 179, Seq. ID No. 181, Seq. ID No. 183, Seq. ID No. 185, Seq. ID No. 187, Seq. ID No. 189, Seq. ID No. 193, Seq. ID No. 195, Seq. ID No. 197, Seq. ID No. 199, Seq. ID No. 201, Seq. ID No. 203, Seq. ID No. 205, Seq. ID No. 207, Seq. ID No. 219, Seq. ID No. 221, Seq. ID No. 223, Seq. ID No. 227, Seq. ID No. 229, Seq. ID No. 231, Seq. ID No. 233, Seq. ID No. 239, Seq. ID No. 241, Seq. ID No. 243, Seq. ID No. 245, Seq. ID No. 247, Seq. ID No. 253, Seq. ID No. 261, Seq. ID No. 263, Seq. ID No. 265, Seq. ID No. 267, Seq. ID No. 269, Seq. ID No. 275, Seq. ID No. 279, Seq. ID No. 281, Seq. ID No. 283, Seq. ID No. 291, Seq. ID No. 293, Seq. ID No. 295, Seq. ID No. 297, Seq. ID No. 299, Seq. ID No. 301, Seq. ID No. 303, Seq. ID No. 305, Seq. ID No. 307, Seq. ID No. 309, Seq. ID No. 311, Seq. ID No. 313, Seq. ID No. 315, Seq. ID No. 317, Seq. ID No. 319, Seq. ID No. 321, Seq. ID No. 323, Seq. ID No. 325, Seq. ID No. 331, Seq. ID No. 333, Seq. ID No. 335, Seq. ID No. 337, Seq. ID No. 339, Seq. ID No. 341, Seq. ID No. 343, Seq. ID No. 345, Seq. ID No. 347, Seq. ID No. 349, Seq. ID No. 351, Seq. ID No. 353, Seq. ID No. 355, Seq. ID No. 361, Seq. ID No. 363, Seq. ID No. 365, Seq. ID No. 367, Seq. ID No. 369, Seq. ID No. 371, Seq. ID No. 377, Seq. ID No. 379, Seq. ID No. 381, Seq. ID No. 383, Seq. ID No. 385, Seq. ID No. 387, Seq. ID No. 389, Seq. ID No. 391, Seq. ID No. 395, Seq. ID No. 397, Seq. ID No. 399, Seq. ID No. 405, Seq. ID No. 407, Seq. ID No. 409, Seq. ID No. 411, Seq. ID No. 413, Seq. ID No. 415, Seq. ID No. 417, Seq. ID No. 419, Seq. ID No. 421, Seq. ID No. 423, Seq. ID No. 425, Seq. ID No. 427, Seq. ID No. 429, Seq. ID No. 431, Seq. ID No. 433, Seq. ID No. 435, Seq. ID No. 437, Seq. ID No. 439, Seq. ID No. 441, Seq. ID No. 443, Seq. ID No. 445, Seq. ID No. 447, Seq. ID No. 449, Seq. ID No. 451, Seq. ID No. 453, Seq. ID No. 459, Seq. ID No. 461, Seq. ID No. 463, Seq. ID No. 465, Seq. ID No. 467, Seq. ID No. 469, Seq. ID No. 471, Seq. ID No. 473, Seq. ID No. 475, Seq. ID No. 479, Seq. ID No. 481, Seq. ID No. 483, Seq. ID No. 485, Seq. ID No. 501, Seq. ID No. 507, Seq. ID No. 517, Seq. ID No. 519, Seq. ID No. 521, Seq. ID No. 523, Seq. ID No. 529, Seq. ID No. 531, Seq. ID No. 533, Seq. ID No. 535, Seq. ID No. 637, Seq. ID No. 539, Seq. ID No. 541, Seq. ID No. 543, Seq. ID No. 551, Seq. ID No. 553, Seq. ID No. 555, Seq. ID No. 559, Seq. ID No. 561, Seq. ID No. 563, Seq. ID No. 565, Seq. ID No. 571, Seq. ID No. 573, Seq. ID No. 581, Seq. ID No. 583, Seq. ID No. 585, Seq. ID No. 587, Seq. ID No. 589, Seq. ID No. 595, Seq. ID No. 597, Seq. ID No. 601, Seq. ID No. 603, Seq. ID No. 605, Seq. ID No. 607, Seq. ID No. 609, Seq. ID No. 611, Seq. ID No. 613, Seq. ID No. 615, Seq. ID No. 619, Seq. ID No. 621, Seq. ID No. 623, Seq. ID No. 625, Seq. ID No. 627, Seq. ID No. 629, Seq. ID No. 631, Seq. ID No. 633, Seq. ID No. 635, Seq. ID No. 649, Seq. ID No. 651, Seq. ID No. 663, Seq. ID No. 665, Seq. ID No. 671, Seq. ID No. 673, Seq. ID No. 681, Seq. ID No. 683, Seq. ID No. 685, Seq. ID No. 687, Seq. ID No. 689, Seq. ID No. 691, Seq. ID No. 693, Seq. ID No. 695, Seq. ID No. 697, Seq. ID No. 699, Seq. ID No. 701, Seq. ID No. 703, Seq. ID No. 705, Seq. ID No. 707, Seq. ID No. 709, Seq. ID No. 711, Seq. ID No. 713, Seq. ID No. 727, Seq. ID No. 729, Seq. ID No. 731, Seq. ID No. 733, Seq. ID No. 735, Seq. ID No. 737, Seq. ID No. 739, Seq. ID No. 741, Seq. ID No. 743, Seq. ID No. 753, Seq. ID No. 767, Seq. ID No. 771, Seq. ID No. 773, Seq. ID No. 775, Seq. ID No. 783, Seq. ID No. 785, Seq. ID No. 787, Seq. ID No. 789, Seq. ID No. 791, Seq. ID No. 793, Seq. ID No. 795, Seq. ID No. 797, Seq. ID No. 799, Seq. ID No. 801, Seq. ID No. 803, Seq. ID No. 805, Seq. ID No. 811, Seq. ID No. 813, Seq. ID No. 815, Seq. ID No. 817, Seq. ID No. 821, Seq. ID No. 823, Seq. ID No. 827, Seq. ID No. 829, Seq. ID No. 831, Seq. ID No. 833, Seq. ID No. 835, Seq. ID No. 837, Seq. ID No. 839, Seq. ID No. 841, Seq. ID No. 843, Seq. ID No. 845, Seq. ID No. 847, Seq. ID No. 849, Seq. ID No. 851, Seq. ID No. 853, Seq. ID No. 855, Seq. ID No. 857, Seq. ID No. 859, Seq. ID No. 861, Seq. ID No. 865, Seq. ID No. 867, Seq. ID No. 869, Seq. ID No. 871, Seq. ID No. 873, Seq. ID No. 875, Seq. ID No. 877, Seq. ID No. 879, Seq. ID No. 881, Seq. ID No. 883, Seq. ID No. 885, Seq. ID No. 887, Seq. ID No. 889, Seq. ID No. 891, Seq. ID No. 895, Seq. ID No. 897, Seq. ID No. 899, Seq. ID No. 903, Seq. ID No. 905, Seq. ID No. 907, Seq. ID No. 909, Seq. ID No. 911, Seq. ID No. 913, Seq. ID No. 915, Seq. ID No. 917, Seq. ID No. 919, Seq. ID No. 921, Seq. ID No. 923, Seq. ID No. 925, Seq. ID No. 927, Seq. ID No. 929, Seq. ID No. 931, Seq. ID No. 933, Seq. ID No. 939, Seq. ID No. 945, Seq. ID No. 947, Seq. ID No. 949, Seq. ID No. 951, Seq. ID No. 953, Seq. ID No. 959, Seq. ID No. 961, Seq. ID No. 963, Seq. ID No. 965, Seq. ID No. 969, Seq. ID No. 971, Seq. ID No. 973, Seq. ID No. 975, Seq. ID No. 977, Seq. ID No. 987, Seq. ID No. 989, Seq. ID No. 991, Seq. ID No. 993, Seq. ID No. 995, Seq. ID No. 997, Seq. ID No. 999, Seq. ID No. 1017, Seq. ID No. 1021, Seq. ID No. 1023, Seq. ID No. 1025, Seq. ID No. 1027, Seq. ID No. 1041, Seq. ID No. 1043, Seq. ID No. 1047, Seq. ID No. 1049, Seq. ID No. 1051, Seq. ID No. 1053, Seq. ID No. 1057, Seq. ID No. 1059, Seq. ID No. 1061, Seq. ID No. 1063, Seq. ID No. 1065, Seq. ID No. 1067, Seq. ID No. 1069, Seq. ID No. 1071, Seq. ID No. 1073, Seq. ID No. 1079, Seq. ID No. 1081, Seq. ID No. 1083, Seq. ID No. 1085, Seq. ID No. 1087, Seq. ID No. 1089, Seq. ID No. 1091, Seq. ID No. 1093, Seq. ID No. 1095, Seq. ID No. 1097, Seq. ID No. 1099, Seq. ID No. 1101, Seq. ID No. 1103, Seq. ID No. 1109, Seq. ID No. 1111, Seq. ID No. 1113, Seq. ID No. 1115, Seq. ID No. 1117, Seq. ID No. 1119, Seq. ID No. 1121, Seq. ID No. 1123, Seq. ID No. 1125, Seq. ID No. 1127, Seq. ID No. 1129, Seq. ID No. 1133, Seq. ID No. 1141, Seq. ID No. 1143, Seq. ID No. 1145, Seq. ID No. 1147, Seq. ID No. 1149, Seq. ID No. 1153, Seq. ID No. 1155, Seq. ID No. 1157, Seq. ID No. 1159, Seq. ID No. 1161, Seq. ID No. 1163, Seq. ID No. 1171, Seq. ID No. 1175, Seq. ID No. 1177, Seq. ID No. 1179, Seq. ID No. 1181, Seq. ID No. 1185, Seq. ID No. 1187, Seq. ID No. 1189, Seq. ID No. 1191, Seq. ID No. 1193, Seq. ID No. 1199, Seq. ID No. 1201, Seq. ID No. 1205, Seq. ID No. 1207, Seq. ID No. 1209, Seq. ID No. 1211, Seq. ID No. 1215, Seq. ID No. 1217, Seq. ID No. 1219, Seq. ID No. 1221, Seq. ID No. 1225, Seq. ID No. 1231, Seq. ID No. 1233, Seq. ID No. 1235, Seq. ID No. 1239, Seq. ID No. 1241, Seq. ID No. 1247, Seq. ID No. 1249, Seq. ID No. 1251, Seq. ID No. 1253, Seq. ID No. 1255, Seq. ID No. 1257, Seq. ID No. 1261, Seq. ID No. 1263, Seq. ID No. 1273, Seq. ID No. 1275, Seq. ID No. 1277, Seq. ID No. 1279, Seq. ID No. 1281, Seq. ID No. 1285, Seq. ID No. 1293, Seq. ID No. 1299, Seq. ID No. 1301, Seq. ID No. 1307, Seq. ID No. 1309, Seq. ID No. 1311, Seq. ID No. 1313, Seq. 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ID No. 1939, Seq. ID No. 1941, Seq. ID No. 1943, Seq. ID No. 1945, Seq. ID No. 1947, Seq. ID No. 1949, Seq. ID No. 1951, Seq. ID No. 1953, Seq. ID No. 1955, Seq. ID No. 1957, Seq. ID No. 1959, Seq. ID No. 1961, Seq. ID No. 1963, Seq. ID No. 1965, Seq. ID No. 1967, Seq. ID No. 1971, Seq. ID No. 1973, Seq. ID No. 1975, Seq. ID No. 1977, Seq. ID No. 1979, Seq. ID No. 1983, Seq. ID No. 1985, Seq. ID No. 1987, Seq. ID No. 1989, Seq. ID No. 1995, Seq. ID No. 1997, Seq. ID No. 1999, Seq. ID No. 2001, Seq. ID No. 2003, Seq. ID No. 2007, Seq. ID No. 2009, Seq. ID No. 2011, Seq. ID No. 2015, Seq. ID No. 2021, Seq. ID No. 2023, Seq. ID No. 2029, Seq. ID No. 2031, Seq. ID No. 2037, Seq. ID No. 2039, Seq. ID No. 2043, Seq. ID No. 2045, Seq. ID No. 2047, Seq. ID No. 2051, Seq. ID No. 2057, Seq. ID No. 2059, Seq. ID No. 2061, Seq. ID No. 2063, Seq. ID No. 2065, Seq. ID No. 2067, Seq. ID No. 2069, Seq. ID No. 2071, Seq. ID No. 2073, Seq. ID No. 2075, Seq. ID No. 2077, Seq. ID No. 2079, Seq. 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ID No. 5299, Seq. ID No. 5301, Seq. ID No. 5303, Seq. ID No. 5305, Seq. ID No. 5307, Seq. ID No. 5309, Seq. ID No. 5311, Seq. ID No. 5313, Seq. ID No. 5315, Seq. ID No. 5317, Seq. ID No. 5319, Seq. ID No. 5321, Seq. ID No. 5323, Seq. ID No. 5325, Seq. ID No. 5333, Seq. ID No. 5335, Seq. ID No. 5337, Seq. ID No. 5339, Seq. ID No. 5343, Seq. ID No. 5345, Seq. ID No. 5347, Seq. ID No. 5349, Seq. ID No. 5351, Seq. ID No. 5353, Seq. ID No. 5355, Seq. ID No. 5357, Seq. ID No. 5359, Seq. ID No. 5361, Seq. ID No. 5363, Seq. ID No. 5365, Seq. ID No. 5367, Seq. ID No. 5369, Seq. ID No. 5371, Seq. ID No. 5373, Seq. ID No. 5375, Seq. ID No. 5381, Seq. ID No. 5383, Seq. ID No. 5389, Seq. ID No. 5391, Seq. ID No. 5393, Seq. ID No. 5395, Seq. ID No. 5397, Seq. ID No. 5399, Seq. ID No. 5401, Seq. ID No. 5403, Seq. ID No. 5407, Seq. ID No. 5409, Seq. ID No. 5411, Seq. ID No. 5417, Seq. ID No. 5419, Seq. ID No. 5421, Seq. ID No. 5423, Seq. ID No. 5425, Seq. ID No. 5427, Seq. ID No. 5429, Seq. ID No. 5431, Seq. ID No. 5435, Seq. ID No. 5437, Seq. ID No. 5439, Seq. ID No. 5441, Seq. ID No. 5443, Seq. ID No. 5445, Seq. ID No. 5447, Seq. ID No. 5449, Seq. ID No. 5451, Seq. ID No. 5455, Seq. ID No. 5457, Seq. ID No. 5467, Seq. ID No. 5469, Seq. ID No. 5471, Seq. ID No. 5473, Seq. ID No. 5475, Seq. ID No. 5477, Seq. ID No. 5479, Seq. ID No. 5481, Seq. ID No. 5483, Seq. ID No. 5485, Seq. ID No. 5487, Seq. ID No. 5489, Seq. ID No. 5493, Seq. ID No. 5495, Seq. ID No. 5499, Seq. ID No. 5501, Seq. ID No. 5503, Seq. ID No. 5505, Seq. ID No. 5507, Seq. ID No. 5511, Seq. ID No. 5519, Seq. ID No. 5521, Seq. ID No. 5523, Seq. ID No. 5527, Seq. ID No. 5535, Seq. ID No. 5537, Seq. ID No. 5539, Seq. ID No. 5541, Seq. ID No. 5547, Seq. ID No. 5549, Seq. ID No. 5551, Seq. ID No. 5553, Seq. ID No. 5555, Seq. ID No. 5557, Seq. ID No. 5559, Seq. ID No. 5561, Seq. ID No. 5563, Seq. ID No. 5565, Seq. ID No. 5567, Seq. ID No. 5571, Seq. ID No. 5573, Seq. ID No. 5575, Seq. ID No. 5577, Seq. ID No. 5579, Seq. ID No. 5581, Seq. ID No. 5583, Seq. ID No. 5585, Seq. ID No. 5599, Seq. ID No. 5601, Seq. ID No. 5603, Seq. ID No. 5605, Seq. ID No. 5607, Seq. ID No. 5613, Seq. ID No. 5615, Seq. ID No. 5617, Seq. ID No. 5619, Seq. ID No. 5627, Seq. ID No. 5629, Seq. ID No. 5631, Seq. ID No. 5635, Seq. ID No. 5645, Seq. ID No. 5647, Seq. ID No. 5651, Seq. ID No. 5653, Seq. ID No. 5655, Seq. ID No. 5657, Seq. ID No. 5661, Seq. ID No. 5663, Seq. ID No. 5665, Seq. ID No. 5669, Seq. ID No. 5671, Seq. ID No. 5673, Seq. ID No. 5675, Seq. ID No. 5677, Seq. ID No. 5679, Seq. ID No. 5691, Seq. ID No. 5693, Seq. ID No. 5695, Seq. ID No. 5697, Seq. ID No. 5701, Seq. ID No. 5707, Seq. ID No. 5713, Seq. ID No. 5715, Seq. ID No. 5717, Seq. ID No. 5721, Seq. ID No. 5723, Seq. ID No. 5725, Seq. ID No. 5727, Seq. ID No. 5731, Seq. ID No. 5737, Seq. ID No. 5741, Seq. ID No. 5743, Seq. ID No. 5745, Seq. ID No. 5747, Seq. ID No. 5749, Seq. ID No. 5751, Seq. ID No. 5753, Seq. ID No. 5755, Seq. ID No. 5757, Seq. ID No. 5759, Seq. ID No. 5761, Seq. ID No. 5769, Seq. ID No. 5773, Seq. ID No. 5775, Seq. ID No. 5777, Seq. ID No. 5779, Seq. ID No. 5781, Seq. ID No. 5787, Seq. ID No. 5789, Seq. ID No. 5793, Seq. ID No. 5795, Seq. ID No. 5799, Seq. ID No. 5801, Seq. ID No. 5803, Seq. ID No. 5805, Seq. ID No. 5807, Seq. ID No. 5809, Seq. ID No. 5811, Seq. ID No. 5813, Seq. ID No. 5815, Seq. ID No. 5817, Seq. ID No. 5819, Seq. ID No. 5821, Seq. ID No. 5823, Seq. ID No. 5825, Seq. ID No. 5827, Seq. ID No. 5831, Seq. ID No. 5833, Seq. ID No. 5835, Seq. ID No. 5837, Seq. ID No. 5839, Seq. ID No. 5841, Seq. ID No. 5843, Seq. ID No. 5845, Seq. ID No. 5847, Seq. ID No. 5849, Seq. ID No. 5851, Seq. ID No. 5853, Seq. ID No. 5855, Seq. ID No. 5857, Seq. ID No. 5859, Seq. ID No. 5861, Seq. ID No. 5863, Seq. ID No. 5865, Seq. ID No. 5867, Seq. ID No. 5869, Seq. ID No. 5871, Seq. ID No. 5873, Seq. ID No. 5875, Seq. ID No. 5877, Seq. ID No. 5881, Seq. ID No. 5887, Seq. ID No. 5891, Seq. ID No. 5897, Seq. ID No. 5903, Seq. ID No. 5907, Seq. ID No. 5911, Seq. ID No. 5913, Seq. ID No. 5915, Seq. ID No. 5917, Seq. ID No. 5919, Seq. ID No. 5925, Seq. ID No. 5931, Seq. ID No. 5933, Seq. ID No. 5935, Seq. ID No. 5937, Seq. ID No. 5941, Seq. ID No. 5943, Seq. ID No. 5945, Seq. ID No. 5947, Seq. ID No. 5949, Seq. ID No. 5951, Seq. ID No. 5953, Seq. ID No. 5955, Seq. ID No. 5957, Seq. ID No. 5959, Seq. ID No. 5961, Seq. ID No. 5963, Seq. ID No. 5965, Seq. ID No. 5967, Seq. ID No. 5969, Seq. ID No. 5971, Seq. ID No. 5973, Seq. ID No. 5975, Seq. ID No. 5977, Seq. ID No. 5979, Seq. ID No. 5981, Seq. ID No. 5983, Seq. ID No. 5985, Seq. ID No. 5987, Seq. ID No. 5989, Seq. ID No. 5991, Seq. ID No. 5993, Seq. ID No. 5995, Seq. ID No. 5997, Seq. ID No. 5999, Seq. ID No. 6001, Seq. ID No. 6003, Seq. ID No. 6005, Seq. ID No. 6007, Seq. ID No. 6009, Seq. ID No. 6011, Seq. ID No. 6013, Seq. ID No. 6015, Seq. ID No. 6017, Seq. ID No. 6019, Seq. ID No. 6021, Seq. ID No. 6029, Seq. ID No. 6031, Seq. ID No. 6033, Seq. ID No. 6035, Seq. ID No. 6037, Seq. ID No. 6039, Seq. ID No. 6041, Seq. ID No. 6045, Seq. ID No. 6049, Seq. ID No. 6051, Seq. ID No. 6055, Seq. ID No. 6057, Seq. ID No. 6061, Seq. ID No. 6065, Seq. ID No. 6069, Seq. ID No. 6071, Seq. ID No. 6073, Seq. ID No. 6075, Seq. ID No. 6077, Seq. ID No. 6079, Seq. ID No. 6081, Seq. ID No. 6083, Seq. ID No. 6085, Seq. ID No. 6093, Seq. ID No. 6097, Seq. ID No. 6099, Seq. ID No. 6101, Seq. ID No. 6105, Seq. ID No. 6113, Seq. ID No. 6119, Seq. ID No. 6121, Seq. ID No. 6123, Seq. ID No. 6125, Seq. ID No. 6127, Seq. ID No. 6129, Seq. ID No. 6131, Seq. ID No. 6133, Seq. ID No. 6139, Seq. ID No. 6141, Seq. ID No. 6143, Seq. ID No. 6145, Seq. ID No. 6147, Seq. ID No. 6149, Seq. ID No. 6151, Seq. ID No. 6153, Seq. ID No. 6155, Seq. ID No. 6157, Seq. ID No. 6167, Seq. ID No. 6171, Seq. ID No. 6173, Seq. ID No. 6175, Seq. ID No. 6177, Seq. ID No. 6179, Seq. ID No. 6181, Seq. ID No. 6193, Seq. ID No. 6195, Seq. ID No. 6199, Seq. ID No. 6201, Seq. ID No. 6207, Seq. ID No. 6211, Seq. ID No. 6213, Seq. ID No. 6215, Seq. ID No. 6219, Seq. ID No. 6231, Seq. ID No. 6233, Seq. ID No. 6239, Seq. ID No. 6247, Seq. ID No. 6251, Seq. ID No. 6255, Seq. ID No. 6257, Seq. ID No. 6261, Seq. ID No. 6269, Seq. ID No. 6271, Seq. ID No. 6277, Seq. ID No. 6279, Seq. ID No. 6281, Seq. ID No. 6287, Seq. ID No. 6291, Seq. ID No. 6293, Seq. ID No. 6295, Seq. ID No. 6297, Seq. ID No. 6299, Seq. ID No. 6305, Seq. ID No. 6307, Seq. ID No. 6309, Seq. ID No. 6311, Seq. ID No. 6313, Seq. ID No. 6315, Seq. ID No. 6317, Seq. ID No. 6319, Seq. ID No. 6321, Seq. ID No. 6323, Seq. ID No. 6329, Seq. ID No. 6331, Seq. ID No. 6333, Seq. ID No. 6335, Seq. ID No. 6337, Seq. ID No. 6339, Seq. ID No. 6341, Seq. ID No. 6343, Seq. ID No. 6345, Seq. ID No. 6347, Seq. ID No. 6349, Seq. ID No. 6351, Seq. ID No. 6353, Seq. ID No. 6355, Seq. ID No. 6357, Seq. ID No. 6359, Seq. ID No. 6361, Seq. ID No. 6367, Seq. ID No. 6369, Seq. ID No. 6371, Seq. ID No. 6373, Seq. ID No. 6375, Seq. ID No. 6379, Seq. ID No. 6385, Seq. ID No. 6387, Seq. ID No. 6389, Seq. ID No. 6391, Seq. ID No. 6393, Seq. ID No. 6395, Seq. ID No. 6397, Seq. ID No. 6399, Seq. ID No. 6401, Seq. ID No. 6403, Seq. ID No. 6405, Seq. ID No. 6407, Seq. ID No. 6409, Seq. ID No. 6411, Seq. ID No. 6413, Seq. ID No. 6417, Seq. ID No. 6419, Seq. ID No. 6421, Seq. ID No. 6423, Seq. ID No. 6433, Seq. ID No. 6435, Seq. ID No. 6437, Seq. ID No. 6439, Seq. ID No. 6441, Seq. ID No. 6443, Seq. ID No. 6445, Seq. ID No. 6447, Seq. ID No. 6449, Seq. ID No. 6451, Seq. ID No. 6453, Seq. ID No. 6455, Seq. ID No. 6457, Seq. ID No. 6459, Seq. ID No. 6461, Seq. ID No. 6463, Seq. ID No. 6465, Seq. ID No. 6467, Seq. ID No. 6469, Seq. ID No. 6471, Seq. ID No. 6475, Seq. ID No. 6477, Seq. ID No. 6481, Seq. ID No. 6483, Seq. ID No. 6485, Seq. ID No. 6487, Seq. ID No. 6489, Seq. ID No. 6491, Seq. ID No. 6493, Seq. ID No. 6495, Seq. ID No. 6499, Seq. ID No. 6501, Seq. ID No. 6503, Seq. ID No. 6505, Seq. ID No. 6507, Seq. ID No. 6509, Seq. ID No. 6511, Seq. ID No. 6513, Seq. ID No. 6515, Seq. ID No. 6519, Seq. ID No. 6521, Seq. ID No. 6523, Seq. ID No. 6525, Seq. ID No. 6527, Seq. ID No. 6529, Seq. ID No. 6531, Seq. ID No. 6533, Seq. ID No. 6535, Seq. ID No. 6537, Seq. ID No. 6539, Seq. ID No. 6545, Seq. ID No. 6547, Seq. ID No. 6549, Seq. ID No. 6551, Seq. ID No. 6553, Seq. ID No. 6559, Seq. ID No. 6561, Seq. ID No. 6563, Seq. ID No. 6565, Seq. ID No. 6567, Seq. ID No. 6569, Seq. ID No. 6575, Seq. ID No. 6577, Seq. ID No. 6579, Seq. ID No. 6583, Seq. ID No. 6585, Seq. ID No. 6587, Seq. ID No. 6589, Seq. ID No. 6591, Seq. ID No. 6605, Seq. ID No. 6607, Seq. ID No. 6609, Seq. ID No. 6611, Seq. ID No. 6613, Seq. ID No. 6615, Seq. ID No. 6617, Seq. ID No. 6619, Seq. ID No. 6621, Seq. ID No. 6623, Seq. ID No. 6625, Seq. ID No. 6627, Seq. ID No. 6629, Seq. ID No. 6633, Seq. ID No. 6635, Seq. ID No. 6641, and Seq. ID No. 6647.

In yet another preferred embodiment, the invention comprises an isolated polynucleotide of the Alloiococcus otitidis genomic sequence encoding a polypeptide, which was identified by BlastP analysis, and the polynucleotide is selected from one of Seq. ID No. 9, Seq. ID No. 17, Seq. ID No. 45, Seq. ID No. 49, Seq. ID No. 53, Seq. ID No. 59, Seq. ID No. 89, Seq. ID No. 145, Seq. ID No. 157, Seq. ID No. 167, Seq. ID No. 171, Seq. ID No. 191, Seq. ID No. 215, Seq. ID No. 217, Seq. ID No. 225, Seq. ID No. 239, Seq. ID No. 253, Seq. ID No. 273, Seq. ID No. 277, Seq. ID No. 289, Seq. ID No. 329, Seq. ID No. 343, Seq. ID No. 345, Seq. ID No. 375, Seq. ID No. 501, Seq. ID No. 505, Seq. ID No. 511, Seq. ID No. 515, Seq. ID No. 529, Seq. ID No. 569, Seq. ID No. 575, Seq. ID No. 593, Seq. ID No. 595, Seq. ID No. 637, Seq. ID No. 659, Seq. ID No. 669, Seq. ID No. 675, Seq. ID No. 681, Seq. ID No. 729, Seq. ID No. 779, Seq. ID No. 819, Seq. ID No. 895, Seq. ID No. 921, Seq. ID No. 935, Seq. ID No. 955, Seq. ID No. 967, Seq. ID No. 985, Seq. ID No. 1017, Seq. ID No. 1039, Seq. ID No. 1075, Seq. ID No. 1089, Seq. ID No. 1137, Seq. ID No. 1223, Seq. ID No. 1241, Seq. ID No. 1315, Seq. ID No. 1331, Seq. ID No. 1369, Seq. ID No. 1459, Seq. ID No. 1517, Seq. ID No. 1561, Seq. ID No. 1563, Seq. ID No. 1567, Seq. ID No. 1571, Seq. ID No. 1573, Seq. ID No. 1601, Seq. ID No. 1607, Seq. ID No. 1613, Seq. ID No. 1619, Seq. ID No. 1641, Seq. ID No. 1647, Seq. ID No. 1653, Seq. ID No. 1657, Seq. ID No. 1665, Seq. ID No. 1699, Seq. ID No. 1713, Seq. ID No. 1751, Seq. ID No. 1771, Seq. ID No. 1785, Seq. ID No. 1789, Seq. ID No. 1791, Seq. ID No. 1797, Seq. ID No. 1811, Seq. ID No. 1817, Seq. ID No. 1819, Seq. ID No. 1821, Seq. ID No. 1871, Seq. ID No. 1895, Seq. ID No. 1905, Seq. ID No. 1913, Seq. ID No. 1919, Seq. ID No. 1923, Seq. ID No. 1965, Seq. ID No. 1971, Seq. ID No. 1999, Seq. ID No. 2047, Seq. ID No. 2055, Seq. ID No. 2091, Seq. ID No. 2093, Seq. ID No. 2115, Seq. ID No. 2119, Seq. ID No. 2127, Seq. ID No. 2165, Seq. ID No. 2179, Seq. ID No. 2207, Seq. ID No. 2223, Seq. ID No. 2227, Seq. ID No. 2241, Seq. ID No. 2253, Seq. ID No. 2263, Seq. ID No. 2269, Seq. ID No. 2275, Seq. ID No. 2301, Seq. ID No. 2315, Seq. ID No. 2329, Seq. ID No. 2333, Seq. ID No. 2343, Seq. ID No. 2345, Seq. ID No. 2363, Seq. ID No. 2373, Seq. ID No. 2391, Seq. ID No. 2417, Seq. ID No. 2429, Seq. ID No. 2465, Seq. ID No. 2475, Seq. ID No. 2483, Seq. ID No. 2513, Seq. ID No. 2525, Seq. ID No. 2589, Seq. ID No. 2613, Seq. ID No. 2651, Seq. ID No. 2669, Seq. ID No. 2677, Seq. ID No. 2687, Seq. ID No. 2689, Seq. ID No. 2693, Seq. ID No. 2703, Seq. ID No. 2709, Seq. ID No. 2715, Seq. ID No. 2751, Seq. ID No. 2753, Seq. ID No. 2767, Seq. ID No. 2787, Seq. ID No. 2791, Seq. ID No. 2803, Seq. ID No. 2867, Seq. ID No. 2871, Seq. ID No. 2907, Seq. ID No. 2919, Seq. ID No. 2921, Seq. ID No. 2923, Seq. ID No. 2927, Seq. ID No. 2933, Seq. ID No. 2957, Seq. ID No. 2979, Seq. ID No. 2999, Seq. ID No. 3005, Seq. ID No. 3019, Seq. ID No. 3031, Seq. ID No. 3035, Seq. ID No. 3055, Seq. ID No. 3067, Seq. ID No. 3085, Seq. ID No. 3165, Seq. ID No. 3183, Seq. ID No. 3189, Seq. ID No. 3197, Seq. ID No. 3211, Seq. ID No. 3251, Seq. ID No. 3257, Seq. ID No. 3259, Seq. ID No. 3297, Seq. ID No. 3319, Seq. ID No. 3323, Seq. ID No. 3335, Seq. ID No. 3337, Seq. ID No. 3355, Seq. ID No. 3359, Seq. ID No. 3377, Seq. ID No. 3397, Seq. ID No. 3405, Seq. ID No. 3415, Seq. ID No. 3425, Seq. ID No. 3427, Seq. ID No. 3461, Seq. ID No. 3463, Seq. ID No. 3487, Seq. ID No. 3493, Seq. ID No. 3497, Seq. ID No. 3507, Seq. ID No. 3519, Seq. ID No. 3521, Seq. ID No. 3529, Seq. ID No. 3535, Seq. ID No. 3629, Seq. ID No. 3635, Seq. ID No. 3727, Seq. ID No. 3759, Seq. ID No. 3771, Seq. ID No. 3793, Seq. ID No. 3839, Seq. ID No. 3851, Seq. ID No. 3863, Seq. ID No. 3865, Seq. ID No. 3883, Seq. ID No. 3891, Seq. ID No. 3913, Seq. ID No. 3925, Seq. ID No. 3929, Seq. ID No. 3975, Seq. ID No. 3981, Seq. ID No. 4027, Seq. ID No. 4039, Seq. ID No. 4061, Seq. ID No. 4073, Seq. ID No. 4081, Seq. ID No. 4103, Seq. ID No. 4111, Seq. ID No. 4137, Seq. ID No. 4225, Seq. ID No. 4247, Seq. ID No. 4343, Seq. ID No. 4379, Seq. ID No. 4389, Seq. ID No. 4469, Seq. ID No. 4473, Seq. ID No. 4481, Seq. ID No. 4485, Seq. ID No. 4493, Seq. ID No. 4529, Seq. ID No. 4643, Seq. ID No. 4705, Seq. ID No. 4713, Seq. ID No. 4717, Seq. ID No. 4813, Seq. ID No. 4815, Seq. ID No. 4825, Seq. ID No. 4827, Seq. ID No. 4833, Seq. ID No. 4837, Seq. ID No. 4851, Seq. ID No. 4863, Seq. ID No. 4875, Seq. ID No. 4879, Seq. ID No. 4893, Seq. ID No. 4901, Seq. ID No. 4919, Seq. ID No. 4931, Seq. ID No. 4959, Seq. ID No. 4963, Seq. ID No. 4985, Seq. ID No. 5113, Seq. ID No. 5115, Seq. ID No. 5117, Seq. ID No. 5125, Seq. ID No. 5141, Seq. ID No. 5183, Seq. ID No. 5201, Seq. ID No. 5205, Seq. ID No. 5213, Seq. ID No. 5219, Seq. ID No. 5279, Seq. ID No. 5285, Seq. ID No. 5331, Seq. ID No. 5381, Seq. ID No. 5389, Seq. ID No. 5405, Seq. ID No. 5411, Seq. ID No. 5419, Seq. ID No. 5433, Seq. ID No. 5463, Seq. ID No. 5477, Seq. ID No. 5491, Seq. ID No. 5509, Seq. ID No. 5513, Seq. ID No. 5525, Seq. ID No. 5529, Seq. ID No. 5537, Seq. ID No. 5567, Seq. ID No. 5599, Seq. ID No. 5621, Seq. ID No. 5637, Seq. ID No. 5699, Seq. ID No. 5723, Seq. ID No. 5733, Seq. ID No. 5761, Seq. ID No. 5791, Seq. ID No. 5895, Seq. ID No. 5901, Seq. ID No. 5903, Seq. ID No. 5909, Seq. ID No. 5913, Seq. ID No. 5919, Seq. ID No. 5929, Seq. ID No. 5939, Seq. ID No. 6001, Seq. ID No. 6043, Seq. ID No. 6053, Seq. ID No. 6057, Seq. ID No. 6089, Seq. ID No. 6095, Seq. ID No. 6103, Seq. ID No. 6111, Seq. ID No. 6117, Seq. ID No. 6165, Seq. ID No. 6169, Seq. ID No. 6185, Seq. ID No. 6191, Seq. ID No. 6209, Seq. ID No. 6229, Seq. ID No. 6257, Seq. ID No. 6263, Seq. ID No. 6271, Seq. ID No. 6275, Seq. ID No. 6289, Seq. ID No. 6303, Seq. ID No. 6365, Seq. ID No. 6369, Seq. ID No. 6383, and Seq. ID No. 6415.

In still yet another preferred embodiment, the invention comprises an isolated polynucleotide of the Alloiococcus otitidis genomic sequence encoding a polypeptide identified by Pfam analysis, and the polynucleotide is selected from one of Seq. ID No. 89, Seq. ID No. 145, Seq. ID No. 155, Seq. ID No. 167, Seq. ID No. 173, Seq. ID No. 191, Seq. ID No. 215, Seq. ID No. 219, Seq. ID No. 221, Seq. ID No. 223, Seq. ID No. 225, Seq. ID No. 233, Seq. ID No. 239, Seq. ID No. 251, Seq. ID No. 253, Seq. ID No. 271, Seq. ID No. 291, Seq. ID No. 331, Seq. ID No. 341, Seq. ID No. 345, Seq. ID No. 375, Seq. ID No. 501, Seq. ID No. 505, Seq. ID No. 511, Seq. ID No. 529, Seq. ID No. 567, Seq. ID No. 569, Seq. ID No. 575, Seq. ID No. 593, Seq. ID No. 595, Seq. ID No. 601, Seq. ID No. 637, Seq. ID No. 649, Seq. ID No. 661, Seq. ID No. 669, Seq. ID No. 675, Seq. ID No. 681, Seq. ID No. 683, Seq. ID No. 729, Seq. ID No. 753, Seq. ID No. 779, Seq. ID No. 827, Seq. ID No. 839, Seq. ID No. 895, Seq. ID No. 939, Seq. ID No. 969, Seq. ID No. 985, Seq. ID No. 1015, Seq. ID No. 1039, Seq. ID No. 1075, Seq. ID No. 1137, Seq. ID No. 1155, Seq. ID No. 1163, Seq. ID No. 1175, Seq. ID No. 1223, Seq. ID No. 1231, Seq. ID No. 1237, Seq. ID No. 1241, Seq. ID No. 1261, Seq. ID No. 1331, Seq. ID No. 1339, Seq. ID No. 1369, Seq. ID No. 1477, Seq. ID No. 1517, Seq. ID No. 1531, Seq. ID No. 1539, Seq. ID No. 1549, Seq. ID No. 1563, Seq. ID No. 1567, Seq. ID No. 1571, Seq. ID No. 1573, Seq. ID No. 1589, Seq. ID No. 1595, Seq. ID No. 1647, Seq. ID No. 1657, Seq. ID No. 1771, Seq. ID No. 1785, Seq. ID No. 1789, Seq. ID No. 1819, Seq. ID No. 1821, Seq. ID No. 1969, Seq. ID No. 2015, Seq. ID No. 2047, Seq. ID No. 2087, Seq. ID No. 2089, Seq. ID No. 2093, Seq. ID No. 211.5, Seq. ID No. 2117, Seq. ID No. 2127, Seq. ID No. 2141, Seq. ID No. 2179, Seq. ID No. 2207, Seq. ID No. 2223, Seq. ID No. 2253, Seq. ID No. 2275, Seq. ID No. 2301, Seq. ID No. 2315, Seq. ID No. 2329, Seq. ID No. 2343, Seq. ID No. 2349, Seq. ID No. 2363, Seq. ID No. 2381, Seq. ID No. 2391, Seq. ID No. 2417, Seq. ID No. 2421, Seq. ID No. 2423, Seq. ID No. 2429, Seq. ID No. 2481, Seq. ID No. 2487, Seq. ID No. 2489, Seq. ID No. 2491, Seq. ID No. 2509, Seq. ID No. 2519, Seq. ID No. 2525, Seq. ID No. 2547, Seq. ID No. 2553, Seq. ID No. 2563, Seq. ID No. 2587, Seq. ID No. 2599, Seq. ID No. 2607, Seq. ID No. 2613, Seq. ID No. 2651, Seq. ID No. 2675, Seq. ID No. 2681, Seq. ID No. 2687, Seq. ID No. 2693, Seq. ID No. 2699, Seq. ID No. 2703, Seq. ID No. 2709, Seq. ID No. 2711, Seq. ID No. 2727, Seq. ID No. 2753, Seq. ID No. 2819, Seq. ID No. 2821, Seq. ID No. 2823, Seq. ID No. 2867, Seq. ID No. 2871, Seq. ID No. 2907, Seq. ID No. 2919, Seq. ID No. 2957, Seq. ID No. 2971, Seq. ID No. 2979, Seq. ID No. 2999, Seq. ID No. 3005, Seq. ID No. 3019, Seq. ID No. 3035, Seq. ID No. 3065; Seq. ID No. 3085, Seq. ID No. 3149, Seq. ID No. 3165, Seq. ID No. 3183, Seq. ID No. 3203, Seq. ID No. 3211, Seq. ID No. 3251, Seq. ID No. 3259, Seq. ID No. 3319, Seq. ID No. 3323, Seq. ID No. 3335, Seq. ID No. 3337, Seq. ID No. 3347, Seq. ID No. 3359, Seq. ID No. 3377, Seq. ID No. 3379, Seq. ID No. 3399, Seq. ID No. 3425, Seq. ID No. 3483, Seq. ID No. 3495, Seq. ID No. 3497, Seq. ID No. 3519, Seq. ID No. 3529, Seq. ID No. 3599, Seq. ID No. 3611, Seq. ID No. 3615, Seq. ID No. 3619, Seq. ID No. 3663, Seq. ID No. 3739, Seq. ID No. 3759, Seq. ID No. 3771, Seq. ID No. 3797, Seq. ID No. 3825, Seq. ID No. 3841, Seq. ID No. 3855, Seq. ID No. 3863, Seq. ID No. 3901, Seq. ID No. 3929, Seq. ID No. 4015, Seq. ID No. 4017, Seq. ID No. 4055, Seq. ID No. 4075, Seq. ID No. 4085, Seq. ID No. 4089, Seq. ID No. 4099, Seq. ID No. 4105, Seq. ID No. 4129, Seq. ID No. 4203, Seq. ID No. 4243, Seq. ID No. 4251, Seq. ID No. 4343, Seq. ID No. 4383, Seq. ID No. 4475, Seq. ID No. 4481, Seq. ID No. 4487, Seq. ID No. 4491, Seq. ID No. 4533, Seq. ID No. 4627, Seq. ID No. 4705, Seq. ID No. 4713, Seq. ID No. 4717, Seq. ID No. 4719, Seq. ID No. 4729, Seq. ID No. 4789, Seq. ID No. 4791, Seq. ID No. 4793, Seq. ID No. 4803, Seq. ID No. 4813, Seq. ID No. 4815, Seq. ID No. 4825, Seq. ID No. 4833, Seq. ID No. 4837, Seq. ID No. 4875, Seq. ID No. 4879, Seq. ID No. 4919, Seq. ID No. 4931, Seq. ID No. 4947, Seq. ID No. 4985, Seq. ID No. 5077, Seq. ID No. 5115, Seq. ID No. 5117, Seq. ID No. 5127, Seq. ID No. 5141, Seq. ID No. 5193, Seq. ID No. 5215, Seq. ID No. 5219, Seq. ID No. 5275, Seq. ID No. 5381, Seq. ID No. 5389, Seq. ID No. 5409, Seq. ID No. 5411, Seq. ID No. 5475, Seq. ID No. 5491, Seq. ID No. 5513, Seq. ID No. 5519, Seq. ID No. 5525, Seq. ID No. 5529, Seq. ID No. 5537, Seq. ID No. 5557, Seq. ID No. 5581, Seq. ID No. 5599, Seq. ID No. 5637, Seq. ID No. 5685, Seq. ID No. 5723, Seq. ID No. 5755, Seq. ID No. 5761, Seq. ID No. 5895, Seq. ID No. 5901, Seq. ID No. 5903, Seq. ID No. 5911, Seq. ID No. 5913, Seq. ID No. 5919, Seq. ID No. 5923, Seq. ID No. 5929, Seq. ID No. 6001, Seq. ID No. 6043, Seq. ID No. 6053, Seq. ID No. 6055, Seq. ID No. 6089, Seq. ID No. 6095, Seq. ID No. 6111, Seq. ID No. 6117, Seq. ID No. 6165, Seq. ID No. 6169, Seq. ID No. 6187, Seq. ID No. 6195, Seq. ID No. 6219, Seq. ID No. 6233, Seq. ID No. 6269, Seq. ID No. 6275, Seq. ID No. 6279, Seq. ID No. 6287, Seq. ID No. 6297, Seq. ID No. 6299, Seq. ID No. 6305, Seq. ID No. 6311, Seq. ID No. 6369, Seq. ID No. 6379, Seq. ID No. 6587, and Seq. ID No. 6591.

In another preferred embodiment, the invention comprises an isolated polynucleotide of the Alloiococcus otitidis genomic sequence encoding a polypeptide, and which has been identified using the proteomic methods used for studying surface proteins of Streptococcus pneumoniae, and the polynucleotide is selected from one of Seq. ID No. 1, Seq. ID No. 5, Seq. ID No. 93, Seq. ID No. 95, Seq. ID No. 103, Seq. ID No. 107, Seq. ID No. 157, Seq. ID No. 223, Seq. ID No. 225, Seq. ID No. 233, Seq. ID No. 239, Seq. ID No. 253, Seq. ID No. 317, Seq. ID No. 321, Seq. ID No. 341, Seq. ID No. 345, Seq. ID No. 353, Seq. ID No. 361, Seq. ID No. 363, Seq. ID No. 365, Seq. ID No. 375, Seq. ID No. 379, Seq. ID No. 383, Seq. ID No. 389, Seq. ID No. 391, Seq. ID No. 397, Seq. ID No. 405, Seq. ID No. 409, Seq. ID No. 415, Seq. ID No. 423, Seq. ID No. 425, Seq. ID No. 427, Seq. ID No. 429, Seq. ID No. 435, Seq. ID No. 437, Seq. ID No. 439, Seq. ID No. 441, Seq. ID No. 443, Seq. ID No. 445, Seq. ID No. 447, Seq. ID No. 449, Seq. ID No. 461, Seq. ID No. 463, Seq. ID No. 465, Seq. ID No. 513, Seq. ID No. 543, Seq. ID No. 551, Seq. ID No. 553, Seq. ID No. 559, Seq. ID No. 595, Seq. ID No. 601, Seq. ID No. 637, Seq. ID No. 649, Seq. ID No. 657, Seq. ID No. 669, Seq. ID No. 675, Seq. ID No. 683, Seq. ID No. 753, Seq. ID No. 929, Seq. ID No. 969, Seq. ID No. 1041, Seq. ID No. 1043, Seq. ID No. 1085, Seq. ID No. 1089, Seq. ID No. 1093, Seq. ID No. 1097, Seq. ID No. 1099, Seq. ID No. 1101, Seq. ID No. 1175, Seq. ID No. 1205, Seq. ID No. 1237, Seq. ID No. 1459, Seq. ID No. 1495, Seq. ID No. 1497, Seq. ID No. 1503, Seq. ID No. 1517, Seq. ID No. 1527, Seq. ID No. 1531, Seq. ID No. 1539, Seq. ID No. 1543, Seq. ID No. 1549, Seq. ID No. 1573, Seq. ID No. 1657, Seq. ID No. 1709, Seq. ID No. 1767, Seq. ID No. 1785, Seq. ID No. 1821, Seq. ID No. 1889, Seq. ID No. 1925, Seq. ID No. 1969, Seq. ID No. 2003, Seq. ID No. 2047, Seq. ID No. 2075, Seq. ID No. 2089, Seq. ID No. 2093, Seq. ID No. 2117, Seq. ID No. 2137, Seq. ID No. 2143, Seq. ID No. 2205, Seq. ID No. 2235, Seq. ID No. 2257, Seq. ID No. 2301, Seq. ID No. 2363, Seq. ID No. 2423, Seq. ID No. 2445, Seq. ID No. 2451, Seq. ID No. 2481, Seq. ID No. 2495, Seq. ID No. 2505, Seq. ID No. 2577, Seq. ID No. 2587, Seq. ID No. 2613, Seq. ID No. 2633, Seq. ID No. 2651, Seq. ID No. 2665, Seq. ID No. 2669, Seq. ID No. 2677, Seq. ID No. 2687, Seq. ID No. 2693, Seq. ID No. 2699, Seq. ID No. 2711, Seq. ID No. 2715, Seq. ID No. 2757, Seq. ID No. 2791, Seq. ID No. 2793, Seq. ID No. 2803, Seq. ID No. 2867, Seq. ID No. 2919, Seq. ID No. 2929, Seq. ID No. 3005, Seq. ID No. 3019, Seq. ID No. 3125, Seq. ID No. 3137, Seq. ID No. 3161, Seq. ID No. 3179, Seq. ID No. 3251, Seq. ID No. 3259, Seq. ID No. 3285, Seq. ID No. 3309, Seq. ID No. 3317, Seq. ID No. 3337, Seq. ID No. 3345, Seq. ID No. 3359, Seq. ID No. 3475, Seq. ID No. 3515, Seq. ID No. 3521, Seq. ID No. 3641, Seq. ID No. 3695, Seq. ID No. 3793, Seq. ID No. 3901, Seq. ID No. 3927, Seq. ID No. 3987, Seq. ID No. 4001, Seq. ID No. 4057, Seq. ID No. 4081, Seq. ID No. 4111, Seq. ID No. 4125, Seq. ID No. 4193, Seq. ID No. 4195, Seq. ID No. 4237, Seq. ID No. 4247, Seq. ID No. 4383, Seq. ID No. 4393, Seq. ID No. 4397, Seq. ID No. 4401, Seq. ID No. 4435, Seq. ID No. 4449, Seq. ID No. 4471, Seq. ID No. 4491, Seq. ID No. 4511, Seq. ID No. 4519, Seq. ID No. 4531, Seq. ID No. 4549, Seq. ID No. 4577, Seq. ID No. 4581, Seq. ID No. 4585, Seq. ID No. 4609, Seq. ID No. 4611, Seq. ID No. 4613, Seq. ID No. 4675, Seq. ID No. 4685, Seq. ID No. 4719, Seq. ID No. 4729, Seq. ID No. 4743, Seq. ID No. 4755, Seq. ID No. 4781, Seq. ID No. 4787, Seq. ID No. 4837, Seq. ID No. 4841, Seq. ID No. 4849, Seq. ID No. 4855, Seq. ID No. 4889, Seq. ID No. 4901, Seq. ID No. 4915, Seq. ID No. 4917, Seq. ID No. 4931, Seq. ID No. 4935, Seq. ID No. 4977, Seq. ID No. 5025, Seq. ID No. 5029, Seq. ID No. 5109, Seq. ID No. 5115, Seq. ID No. 5117, Seq. ID No. 5155, Seq. ID No. 5185, Seq. ID No. 5201, Seq. ID No. 5203, Seq. ID No. 5219, Seq. ID No. 5261, Seq. ID No. 5289, Seq. ID No. 5295, Seq. ID No. 5377, Seq. ID No. 5389, Seq. ID No. 5399, Seq. ID No. 5411, Seq. ID No. 5537, Seq. ID No. 5621, Seq. ID No. 5627, Seq. ID No. 5657, Seq. ID No. 5675, Seq. ID No. 5717, Seq. ID No. 5777, Seq. ID No. 5859, Seq. ID No. 5901, Seq. ID No. 5913, Seq. ID No. 5919, Seq. ID No. 5925, Seq. ID No. 5933, Seq. ID No. 6055, Seq. ID No. 6129, Seq. ID No. 6133, Seq. ID No. 6187, Seq. ID No. 6193, Seq. ID No. 6219, Seq. ID No. 6271, Seq. ID No. 6277, Seq. ID No. 6369, Seq. ID No. 6375, Seq. ID No. 6379, Seq. ID No. 6389, Seq. ID No. 6591, and Seq. ID No. 6605.

In another preferred embodiment, the invention comprises an isolated polynucleotide of the Alloiococcus otitidis genomic sequence encoding a polypeptide, wherein the polypeptide encoded by the polynucleotide was identified using HMM LPXTG motif finder as having a LPXTG motif, and wherein the polypeptide is covalently attached to the peptidoglycan layer, and the polynucleotide is selected from one Seq. ID No. 503, Seq. ID No. 505, Seq. ID No. 1315, Seq. ID No. 1317, Seq. ID No. 1363, Seq. ID No. 1365, Seq. ID No. 1367, Seq. ID No. 1369, Seq. ID No. 1559, Seq. ID No. 1561, Seq. ID No. 1581, Seq. ID No. 1739, Seq. ID No. 1741, Seq. ID No. 2811, Seq. ID No. 2813, Seq. ID No. 3619, Seq. ID No. 5587, Seq. ID No. 5589, Seq. ID No. 5591, Seq. ID No. 5781, Seq. ID No. 5783, and Seq. ID No. 6103.

In another preferred embodiment, the invention comprises an isolated polynucleotide of the Alloiococcus otitidis genomic sequence encoding a lipoprotein as predicted by HMM Lipo software program, and the polynucleotide is selected from Seq. ID No. 45, Seq. ID No. 47, Seq. ID No. 171, Seq. ID No. 225, Seq. ID No. 419, Seq. ID No. 513, Seq. ID No. 575, Seq. ID No. 591, Seq. ID No. 593, Seq. ID No. 657, Seq. ID No. 659, Seq. ID No. 669, Seq. ID No. 675, Seq. ID No. 745, Seq. ID No. 747, Seq. ID No. 935, Seq. ID No. 1045, Seq. ID No. 1075, Seq. ID No. 1137, Seq. ID No. 1173, Seq. ID No. 1191, Seq. ID No. 1193, Seq. ID No. 1195, Seq. ID No. 1563, Seq. ID No. 1661, Seq. ID No. 1663, Seq. ID No. 1665, Seq. ID No. 1791, Seq. ID No. 1797, Seq. ID No. 1917, Seq. ID No. 1969, Seq. ID No. 2115, Seq. ID No. 2159, Seq. ID No. 2429, Seq. ID No. 2527, Seq. ID No. 2699, Seq. ID No. 2815, Seq. ID No. 2875, Seq. ID No. 2975, Seq. ID No. 2977, Seq. ID No. 2991, Seq. ID No. 3043, Seq. ID No. 3323, Seq. ID No. 3337, Seq. ID No. 4133, Seq. ID No. 4137, Seq. ID No. 4481, Seq. ID No. 4705, Seq. ID No. 4827, Seq. ID No. 4869, Seq. ID No. 5115, Seq. ID No. 5377, Seq. ID No. 5379, Seq. ID No. 5491, Seq. ID No. 5509, Seq. ID No. 5513, Seq. ID No. 5525, Seq. ID No. 5529, Seq. ID No. 5531, Seq. ID No. 5889, Seq. ID No. 5909, Seq. ID No. 6025, Seq. ID No. 6027, Seq. ID No. 6087, Seq. ID No. 6089, Seq. ID No. 6325, Seq. ID No. 6327, Seq. ID No. 6415, Seq. ID No. 6637, Seq. ID No. 6639, and Seq. ID No. 6645.

In another preferred embodiment, the invention comprises an isolated polynucleotide of the Alloiococcus otitidis genomic sequence encoding a polypeptide, wherein the polypeptide encoded by the polynucleotide is predicted by HMM program to be non-covalently bound to the peptidoglycan layer, and the polynucleotide is selected from Seq. ID No. 3589, Seq. ID No. 3987, Seq. ID No. 5219, and Seq. ID No. 5337.

In another preferred embodiment, the invention comprises an isolated polynucleotide of the Alloiococcus otitidis genomic sequence encoding a polypeptide, wherein the polypeptide encodes a polypeptide having a RGDX motif wherein X is not a proline, and the polynucleotide is selected from Seq. ID No. 37, Seq. ID No. 99, Seq. ID No. 107, Seq. ID No. 109, Seq. ID No. 111, Seq. ID No. 351, Seq. ID No. 353, Seq. ID No. 465, Seq. ID No. 467, Seq. ID No. 469, Seq. ID No. 471, Seq. ID No. 683, Seq. ID No. 821, Seq. ID No. 823, Seq. ID No. 1021, Seq. ID No. 1023, Seq. ID No. 1157, Seq. ID No. 1159, Seq. ID No. 1233, Seq. ID No. 1333, Seq. ID No. 1335, Seq. ID No. 1449, Seq. ID No. 1559, Seq. ID No. 1561, Seq. ID No. 1563, Seq. ID No. 1625, Seq. ID No. 1777, Seq. ID No. 1827, Seq. ID No. 1829, Seq. ID No. 1871, Seq. ID No. 1925, Seq. ID No. 2135, Seq. ID No. 2145, Seq. ID No. 2173, Seq. ID No. 2175, Seq. ID No. 2177, Seq. ID No. 2179, Seq. ID No. 2259, Seq. ID No. 2317, Seq. ID No. 2319, Seq. ID No. 2321, Seq. ID No. 2323, Seq. ID No. 2325, Seq. ID No. 2327, Seq. ID No. 2329, Seq. ID No. 2401, Seq. ID No. 2671, Seq. ID No. 2863, Seq. ID No. 2869, Seq. ID No. 2919, Seq. ID No. 2921, Seq. ID No. 2993, Seq. ID No. 3087, Seq. ID No. 3137, Seq. ID No. 3279, Seq. ID No. 3281, Seq. ID No. 3283, Seq. ID No. 3333, Seq. ID No. 3335, Seq. ID No. 3497, Seq. ID No. 3499, Seq. ID No. 3501, Seq. ID No. 3533, Seq. ID No. 3671, Seq. ID No. 3673, Seq. ID No. 3675, Seq. ID No. 3837, Seq. ID No. 3839, Seq. ID No. 3841, Seq. ID No. 3843, Seq. ID No. 3929, Seq. ID No. 3961, Seq. ID No. 4037, Seq. ID No. 4193, Seq. ID No. 4239, Seq. ID No. 4327, Seq. ID No. 4329, Seq. ID No. 4333, Seq. ID No. 4393, Seq. ID No. 4463, Seq. ID No. 4465, Seq. ID No. 4467, Seq. ID No. 4597, Seq. ID No. 4629, Seq. ID No. 4631, Seq. ID No. 4675, Seq. ID No. 4677, Seq. ID No. 4679, Seq. ID No. 4689, Seq. ID No. 4691, Seq. ID No. 4693, Seq. ID No. 4781, Seq. ID No. 4799, Seq. ID No. 4801, Seq. ID No. 4803, Seq. ID No. 4861, Seq. ID No. 5009, Seq. ID No. 5143, Seq. ID No. 5145, Seq. ID No. 5179, Seq. ID No. 5181, Seq. ID No. 5183, Seq. ID No. 5249, Seq. ID No. 5251, Seq. ID No. 5253, Seq. ID No. 5259, Seq. ID No. 5261, Seq. ID No. 5293, Seq. ID No. 5295, Seq. ID No. 5297, Seq. ID No. 5299, Seq. ID No. 5307, Seq. ID No. 5309, Seq. ID No. 5411, Seq. ID No. 5535, Seq. ID No. 5537, Seq. ID No. 5745, Seq. ID No. 5821, Seq. ID No. 5823, Seq. ID No. 5825, Seq. ID No. 6029, Seq. ID No. 6171, Seq. ID No. 6307, Seq. ID No. 6309, and Seq. ID No. 6311.

In another preferred embodiment, the polynucleotide is selected from the Alloiococcus otitidis polynucleotides that are predicted by BlastP analysis as encoding polypeptides involved in capsule biosynthesis and transport, and the polynucleotide is selected from Seq. ID No. 49, Seq. ID No. 51, Seq. ID No. 53, Seq. ID No. 59, Seq. ID No. 195, Seq. ID No. 689, Seq. ID No. 703, Seq. ID No. 925, Seq. ID No. 1597, Seq. ID No. 1601, Seq. ID No. 1607, Seq. ID No. 1611, Seq. ID No. 1613, Seq. ID No. 1713, Seq. ID No. 2029, Seq. ID No. 2263, Seq. ID No. 2269, Seq. ID No. 2373, Seq. ID No. 2437, Seq. ID No. 2651, Seq. ID No. 2767, Seq. ID No. 2907, Seq. ID No. 3397, Seq. ID No. 3399, Seq. ID No. 3479, Seq. ID No. 3487, Seq. ID No. 3491, Seq. ID No. 3493, Seq. ID No. 3495, Seq. ID No. 3497, Seq. ID No. 3519, Seq. ID No. 3521, Seq. ID No. 3529, Seq. ID No. 3535, Seq. ID No. 3561, Seq. ID No. 3883, Seq. ID No. 3891, Seq. ID No. 3981, and Seq. ID No. 4087.

In yet another preferred embodiment, the polynucleotide is selected from the Alloiococcus otitidis polynucleotides that encodes a polypeptide identified by BlastP analysis as being localized within the capsular loci of the Alloiococcus otitidis genome, and the polynucleotide is selected from one of Seq. ID No. 45, Seq. ID No. 47, Seq. ID No. 51, Seq. ID No. 53, Seq. ID No. 55, Seq. ID No. 57, Seq. ID No. 59, Seq. ID No. 683, Seq. ID No. 685, Seq. ID No. 687, Seq. ID No. 689, Seq. ID No. 691, Seq. ID No. 693, Seq. ID No. 695, Seq. ID No. 697, Seq. ID No. 699, Seq. ID No. 701, Seq. ID No. 703, Seq. ID No. 705, Seq. ID No. 707, Seq. ID No. 709, Seq. ID No. 711, Seq. ID No. 713, Seq. ID No. 715, Seq. ID No. 717, Seq. ID No. 719, Seq. ID No. 721, Seq. ID No. 723, Seq. ID No. 725, Seq. ID No. 727, Seq. ID No. 729, Seq. ID No. 731, Seq. ID No. 733, Seq. ID No. 735, Seq. ID No. 737, Seq. ID No. 739, Seq. ID No. 741, Seq. ID No. 743, Seq. ID No. 745, Seq. ID No. 747, Seq. ID No. 749, Seq. ID No. 751, Seq. ID No. 753, Seq. ID No. 3389, Seq. ID No. 3391, Seq. ID No. 3393, Seq. ID No. 3395, Seq. ID No. 3397, Seq. ID No. 3399, Seq. ID No. 3401, Seq. ID No. 3403, Seq. ID No. 3405, Seq. ID No. 3407, Seq. ID No. 3409, Seq. ID No. 3411, Seq. ID No. 3413, Seq. ID No. 3415, Seq. ID No. 3417, Seq. ID No. 3419, Seq. ID No. 3421, Seq. ID No. 3423, Seq. ID No. 3425, Seq. ID No. 3427, Seq. ID No. 3429, Seq. ID No. 3431, Seq. ID No. 3433, Seq. ID No. 3435, Seq. ID No. 3437, Seq. ID No. 3439, Seq. ID No. 3441, Seq. ID No. 3443, Seq. ID No. 3445, Seq. ID No. 3447, Seq. ID No. 3449, Seq. ID No. 3451, Seq. ID No. 3453, Seq. ID No. 3455, Seq. ID No. 3457, Seq. ID No. 3459, Seq. ID No. 3461, Seq. ID No. 3463, Seq. ID No. 3465, Seq. ID No. 3467, Seq. ID No. 3469, Seq. ID No. 3471, Seq. ID No. 3473, Seq. ID No. 3475, Seq. ID No. 3477, Seq. ID No. 3479, Seq. ID No. 3481, Seq. ID No. 3483, Seq. ID No. 3485, Seq. ID No. 3487, Seq. ID No. 3489, Seq. ID No. 3491, Seq. ID No. 3493, Seq. ID No. 3495, Seq. ID No. 3497, Seq. ID No. 3499, Seq. ID No. 3501, Seq. ID No. 3503, Seq. ID No. 3505, Seq. ID No. 3507, Seq. ID No. 3509, Seq. ID No. 3511, Seq. ID No. 3513, Seq. ID No. 3515, Seq. ID No. 3517, Seq. ID No. 3519, Seq. ID No. 3521, Seq. ID No. 3523, Seq. ID No. 3525, Seq. ID No. 3527, Seq. ID No. 3529, Seq. ID No. 3531, Seq. ID No. 3533, Seq. ID No. 3535, Seq. ID No. 3537, Seq. ID No. 3539, Seq. ID No. 3541, Seq. ID No. 3543, Seq. ID No. 3545, Seq. ID No. 3547, Seq. ID No. 3549, Seq. ID No. 3551, Seq. ID No. 3553, Seq. ID No. 3555, Seq. ID No. 3557, Seq. ID No. 3559, and Seq. ID No. 3561.

In another preferred embodiment, the polynucleotide is selected from the Alloiococcus otitidis polynucleotides identified by BlastP analysis as encoding polypeptides, which are associated with sporulation, and the polynucleotide is selected from one of Seq. ID No. 1137, Seq. ID No. 1455, Seq. ID No. 2137, Seq. ID No. 2141, Seq. ID No. 2165, Seq. ID No. 2179, Seq. ID No. 2301, Seq. ID No. 2753, Seq. ID No. 4211, Seq. ID No. 4251, Seq. ID No. 4327, Seq. ID No. 4569, Seq. ID No. 4719, and Seq. ID No. 4729.

In another preferred embodiment, the polynucleotide is selected from the Alloiococcus otitidis polynucleotides identified by BlastP analysis as being unique and having a BlastP ‘E’ value of >e⁻¹⁰, and the polynucleotide is selected from one of Seq. ID No. 7, Seq. ID No. 19, Seq. ID No. 21, Seq. ID No. 23, Seq. ID No. 31, Seq. ID No. 39, Seq. ID No. 65, Seq. ID No. 67, Seq. ID No. 69, Seq. ID No. 91, Seq. ID No. 99, Seq. ID No. 105, Seq. ID No. 113, Seq. ID No. 115, Seq. ID No. 123, Seq. ID No. 125, Seq. ID No. 127, Seq. ID No. 131, Seq. ID No. 133, Seq. ID No. 139, Seq. ID No. 151, Seq. ID No. 159, Seq. ID No. 161, Seq. ID No. 163, Seq. ID No. 165, Seq. ID No. 169, Seq. ID No. 185, Seq. ID No. 189, Seq. ID No. 193, Seq. ID No. 229, Seq. ID No. 231, Seq. ID No. 255, Seq. ID No. 257, Seq. ID No. 259, Seq. ID No. 275, Seq. ID No. 337, Seq. ID No. 339, Seq. ID No. 347, Seq. ID No. 349, Seq. ID No. 357, Seq. ID No. 359, Seq. ID No. 369, Seq. ID No. 371, Seq. ID No. 377, Seq. ID No. 385, Seq. ID No. 387, Seq. ID No. 393, Seq. ID No. 399, Seq. ID No. 401, Seq. ID No. 403, Seq. ID No. 407, Seq. ID No. 419, Seq. ID No. 431, Seq. ID No. 477, Seq. ID No. 495, Seq. ID No. 507, Seq. ID No. 519, Seq. ID No. 541, Seq. ID No. 545, Seq. ID No. 547, Seq. ID No. 549, Seq. ID No. 557, Seq. ID No. 589, Seq. ID No. 617, Seq. ID No. 619, Seq. ID No. 633, Seq. ID No. 639, Seq. ID No. 641, Seq. ID No. 643, Seq. ID No. 645, Seq. ID No. 647, Seq. ID No. 651, Seq. ID No. 653, Seq. ID No. 655, Seq. ID No. 667, Seq. ID No. 691, Seq. ID No. 693, Seq. ID No. 695, Seq. ID No. 697, Seq. ID No. 715, Seq. ID No. 717, Seq. ID No. 719, Seq. ID No. 731, Seq. ID No. 733, Seq. ID No. 741, Seq. ID No. 743, Seq. ID No. 745, Seq. ID No. 747, Seq. ID No. 749, Seq. ID No. 751, Seq. ID No. 755, Seq. ID No. 757, Seq. ID No. 759, Seq. ID No. 761, Seq. ID No. 763, Seq. ID No. 765, Seq. ID No. 767, Seq. ID No. 801, Seq. ID No. 803, Seq. ID No. 805, Seq. ID No. 807, Seq. ID No. 809, Seq. ID No. 811, Seq. ID No. 813, Seq. ID No. 833, Seq. ID No. 841, Seq. ID No. 849, Seq. ID No. 851, Seq. ID No. 853, Seq. ID No. 855, Seq. ID No. 887, Seq. ID No. 889, Seq. ID No. 891, Seq. ID No. 903, Seq. ID No. 905, Seq. ID No. 909, Seq. ID No. 937, Seq. ID No. 941, Seq. ID No. 943, Seq. ID No. 951, Seq. ID No. 957, Seq. ID No. 973, Seq. ID No. 975, Seq. ID No. 987, Seq. ID No. 1005, Seq. ID No. 1007, Seq. ID No. 1009, Seq. ID No. 1011, Seq. ID No. 1019, Seq. ID No. 1025, Seq. ID No. 1027, Seq. ID No. 1045, Seq. ID No. 1047, Seq. ID No. 1071, Seq. ID No. 1073, Seq. ID No. 1077, Seq. ID No. 1105, Seq. ID No. 1107, Seq. ID No. 1111, Seq. ID No. 1131, Seq. ID No. 1135, Seq. ID No. 1139, Seq. ID No. 1151, Seq. ID No. 1153, Seq. ID No. 1165, Seq. ID No. 1167, Seq. ID No. 1169, Seq. ID No. 1171, Seq. ID No. 1173, Seq. ID No. 1181, Seq. ID No. 1183, Seq. ID No. 1185, Seq. ID No. 1187, Seq. ID No. 1189, Seq. ID No. 1191, Seq. ID No. 1193, Seq. ID No. 1195, Seq. ID No. 1197, Seq. ID No. 1199, Seq. ID No. 1201, Seq. ID No. 1203, Seq. ID No. 1207, Seq. ID No. 1213, Seq. ID No. 1227, Seq. ID No. 1229, Seq. ID No. 1239, Seq. ID No. 1243, Seq. ID No. 1245, Seq. ID No. 1247, Seq. ID No. 1249, Seq. ID No. 1259, Seq. ID No. 1265, Seq. ID No. 1267, Seq. ID No. 1269, Seq. ID No. 1271, Seq. ID No. 1273, Seq. ID No. 1275, Seq. ID No. 1277, Seq. ID No. 1279, Seq. ID No. 1281, Seq. ID No. 1283, Seq. ID No. 1285, Seq. ID No. 1287, Seq. ID No. 1289, Seq. ID No. 1291, Seq. ID No. 1293, Seq. ID No. 1295, Seq. ID No. 1297, Seq. ID No. 1299, Seq. ID No. 1301, Seq. ID No. 1303, Seq. ID No. 1305, Seq. ID No. 1307, Seq. ID No. 1309, Seq. ID No. 1311, Seq. ID No. 1313, Seq. ID No. 1319, Seq. ID No. 1321, Seq. ID No. 1323, Seq. ID No. 1325, Seq. ID No. 1327, Seq. ID No. 1337, Seq. ID No. 1341, Seq. ID No. 1343, Seq. ID No. 1347, Seq. ID No. 1349, Seq. ID No. 1351, Seq. ID No. 1353, Seq. ID No. 1355, Seq. ID No. 1371, Seq. ID No. 1379, Seq. ID No. 1381, Seq. ID No. 1389, Seq. ID No. 1397, Seq. ID No. 1399, Seq. ID No. 1401, Seq. ID No. 1417, Seq. ID No. 1419, Seq. ID No. 1421, Seq. ID No. 1423, Seq. ID No. 1439, Seq. ID No. 1445, Seq. ID No. 1447, Seq. ID No. 1457, Seq. ID No. 1465, Seq. ID No. 1479, Seq. ID No. 1511, Seq. ID No. 1551, Seq. ID No. 1553, Seq. ID No. 1555, Seq. ID No. 1557, Seq. ID No. 1579, Seq. ID No. 1609, Seq. ID No. 1621, Seq. ID No. 1623, Seq. ID No. 1625, Seq. ID No. 1627, Seq. ID No. 1629, Seq. ID No. 1631, Seq. ID No. 1633, Seq. ID No. 1639, Seq. ID No. 1643, Seq. ID No. 1655, Seq. ID No. 1667, Seq. ID No. 1671, Seq. ID No. 1693, Seq. ID No. 1695, Seq. ID No. 1701, Seq. ID No. 1703, Seq. ID No. 1705, Seq. ID No. 1721, Seq. ID No. 1723, Seq. ID No. 1731, Seq. ID No. 1737,.Seq. ID No. 1743, Seq. ID No. 1759, Seq. ID No. 1763, Seq. ID No. 1773, Seq. ID No. 1775, Seq. ID No. 1777, Seq. ID No. 1779, Seq. ID No. 1781, Seq. ID No. 1799, Seq. ID No. 1801, Seq. ID No. 1803, Seq. ID No. 1807, Seq. ID No. 1823, Seq. ID No. 1831, Seq. ID No. 1851, Seq. ID No. 1857, Seq. ID No. 1875, Seq. ID No. 1899, Seq. ID No. 1915, Seq. ID No. 1927, Seq. ID No. 1929, Seq. ID No. 1973, Seq. ID No. 1977, Seq. ID No. 1981, Seq. ID No. 2005, Seq. ID No. 2007, Seq. ID No. 2009, Seq. ID No. 2011, Seq. ID No. 2017, Seq. ID No. 2019, Seq. ID No. 2023, Seq. ID No. 2025, Seq. ID No. 2027, Seq. ID No. 2039, Seq. ID No. 2041, Seq. ID No. 2043, Seq. ID No. 2045, Seq. ID No. 2049, Seq. ID No. 2081, Seq. ID No. 2083, Seq. ID No. 2085, Seq. ID No. 2105, Seq. ID No. 2107, Seq. ID No. 2109, Seq. ID No. 2111, Seq. ID No. 2129, Seq. ID No. 2131, Seq. ID No. 2133, Seq. ID No. 2145, Seq. ID No. 2155, Seq. ID No. 2157, Seq. ID No. 2159, Seq. ID No. 2161, Seq. ID No. 2171, Seq. ID No. 2187, Seq. ID No. 2189, Seq. ID No. 2201, Seq. ID No. 2203, Seq. ID No. 2209, Seq. ID No. 2211, Seq. ID No. 2219, Seq. ID No. 2225, Seq. ID No. 2243, Seq. ID No. 2245, Seq. ID No. 2247, Seq. ID No. 2249, Seq. ID No. 2251, Seq. ID No. 2255, Seq. ID No. 2277, Seq. ID No. 2279, Seq. ID No. 2341, Seq. ID No. 2351, Seq. ID No. 2353, Seq. ID No. 2355, Seq. ID No. 2357, Seq. ID No. 2359, Seq. ID No. 2365, Seq. ID No. 2367, Seq. ID No. 2371, Seq. ID No. 2375, Seq. ID No. 2393, Seq. ID No. 2395, Seq. ID No. 2425, Seq. ID No. 2427, Seq. ID No. 2431, Seq. ID No. 2439, Seq. ID No. 2441, Seq. ID No. 2443, Seq. ID No. 2447, Seq. ID No. 2459, Seq. ID No. 2479, Seq. ID No. 2493, Seq. ID No. 2501, Seq. ID No. 2503, Seq. ID No. 2521, Seq. ID No. 2523, Seq. ID No. 2527, Seq. ID No. 2591, Seq. ID No. 2601, Seq. ID No. 2603, Seq. ID No. 2611, Seq. ID No. 2627, Seq. ID No. 2629, Seq. ID No. 2653, Seq. ID No. 2661, Seq. ID No. 2691, Seq. ID No. 2695, Seq. ID No. 2697, Seq. ID No. 2717, Seq. ID No. 2729, Seq. ID No. 2731, Seq. ID No. 2733, Seq. ID No. 2735, Seq. ID No. 2739, Seq. ID No. 2741, Seq. ID No. 2743, Seq. ID No. 2777, Seq. ID No. 2779, Seq. ID No. 2781, Seq. ID No. 2783, Seq. ID No. 2801, Seq. ID No. 2805, Seq. ID No. 2807, Seq. ID No. 2809, Seq. ID No. 2811, Seq. ID No. 2813, Seq. ID No. 2815, Seq. ID No. 2817, Seq. ID No. 2819, Seq. ID No. 2829, Seq. ID No. 2831, Seq. ID No. 2833, Seq. ID No. 2835, Seq. ID No. 2837, Seq. ID No. 2839, Seq. ID No. 2841, Seq. ID No. 2845, Seq. ID No. 2849, Seq. ID No. 2851, Seq. ID No. 2853, Seq. ID No. 2855, Seq. ID No. 2857, Seq. ID No. 2859, Seq. ID No. 2861, Seq. ID No. 2865, Seq. ID No. 2873, Seq. ID No. 2875, Seq. ID No. 2877, Seq. ID No. 2883, Seq. ID No. 2885, Seq. ID No. 2887, Seq. ID No. 2889, Seq. ID No. 2893, Seq. ID No. 2895, Seq. ID No. 2903, Seq. ID No. 2909, Seq. ID No. 2935, Seq. ID No. 2937, Seq. ID No. 2939, Seq. ID No. 2941, Seq. ID No. 2943, Seq. ID No. 2945, Seq. ID No. 2947, Seq. ID No. 2949, Seq. ID No. 2951, Seq. ID No. 2953, Seq. ID No. 2965, Seq. ID No. 2967, Seq. ID No. 2973, Seq. ID No. 2975, Seq. ID No. 2977, Seq. ID No. 2981, Seq. ID No. 2983, Seq. ID No. 2985, Seq. ID No. 2987, Seq. ID No. 2989, Seq. ID No. 2991, Seq. ID No. 3001, Seq. ID No. 3007, Seq. ID No. 3009, Seq. ID No. 3011, Seq. ID No. 3021, Seq. ID No. 3023, Seq. ID No. 3041, Seq. ID No. 3045, Seq. ID No. 3071, Seq. ID No. 3087, Seq. ID No. 3105, Seq. ID No. 3107, Seq. ID No. 3119, Seq. ID No. 3121, Seq. ID No. 3123, Seq. ID No. 3151, Seq. ID No. 3153, Seq. ID No. 3167, Seq. ID No. 3173, Seq. ID No. 3175, Seq. ID No. 3177, Seq. ID No. 3181, Seq. ID No. 3193, Seq. ID No. 3213, Seq. ID No. 3215, Seq. ID No. 3217, Seq. ID No. 3219, Seq. ID No. 3221, Seq. ID No. 3223, Seq. ID No. 3231, Seq. ID No. 3233, Seq. ID No. 3235, Seq. ID No. 3237, Seq. ID No. 3239, Seq. ID No. 3241, Seq. ID No. 3243, Seq. ID No. 3245, Seq. ID No. 3247, Seq. ID No. 3249, Seq. ID No. 3261, Seq. ID No. 3263, Seq. ID No. 3265, Seq. ID No. 3267, Seq. ID No. 3269, Seq. ID No. 3271, Seq. ID No. 3273, Seq. ID No. 3275, Seq. ID No. 3277, Seq. ID No. 3325, Seq. ID No. 3331, Seq. ID No. 3339, Seq. ID No. 3341, Seq. ID No. 3349, Seq. ID No. 3361, Seq. ID No. 3363, Seq. ID No. 3369, Seq. ID No. 3371, Seq. ID No. 3389, Seq. ID No. 3403, Seq. ID No. 3417, Seq. ID No. 3419, Seq. ID No. 3421, Seq. ID No. 3433, Seq. ID No. 3437, Seq. ID No. 3441, Seq. ID No. 3443, Seq. ID No. 3445, Seq. ID No. 3447, Seq. ID No. 3473, Seq. ID No. 3481, Seq. ID No. 3483, Seq. ID No. 3489, Seq. ID No. 3503, Seq. ID No. 3505, Seq. ID No. 3509, Seq. ID No. 3511, Seq. ID No. 3523, Seq. ID No. 3525, Seq. ID No. 3531, Seq. ID No. 3533, Seq. ID No. 3539, Seq. ID No. 3541, Seq. ID No. 3543, Seq. ID No. 3545, Seq. ID No. 3547, Seq. ID No. 3555, Seq. ID No. 3557, Seq. ID No. 3563, Seq. ID No. 3565, Seq. ID No. 3571, Seq. ID No. 3573, Seq. ID No. 3581, Seq. ID No. 3587, Seq. ID No. 3591, Seq. ID No. 3593, Seq. ID No. 3595, Seq. ID No. 3611, Seq. ID No. 3613, Seq. ID No. 3617, Seq. ID No. 3619, Seq. ID No. 3621, Seq. ID No. 3623, Seq. ID No. 3625, Seq. ID No. 3631, Seq. ID No. 3637, Seq. ID No. 3639, Seq. ID No. 3655, Seq. ID No. 3657, Seq. ID No. 3659, Seq. ID No. 3661, Seq. ID No. 3677, Seq. ID No. 3679, Seq. ID No. 3683, Seq. ID No. 3685, Seq. ID No. 3701, Seq. ID No. 3703, Seq. ID No. 3717, Seq. ID No. 3719, Seq. ID No. 3721, Seq. ID No. 3723, Seq. ID No. 3729, Seq. ID No. 3731, Seq. ID No. 3733, Seq. ID No. 3735, Seq. ID No. 3737, Seq. ID No. 3739, Seq. ID No. 3741, Seq. ID No. 3749, Seq. ID No. 3751, Seq. ID No. 3753, Seq. ID No. 3755, Seq. ID No. 3761, Seq. ID No. 3781, Seq. ID No. 3783, Seq. ID No. 3785, Seq. ID No. 3787, Seq. ID No. 3789, Seq. ID No. 3791, Seq. ID No. 3799, Seq. ID No. 3807, Seq. ID No. 3809, Seq. ID No. 3811, Se4. ID No. 3813, Seq. ID No. 3815, Seq. ID No. 3817, Seq. ID No. 3827, Seq. ID No. 3829, Seq. ID No. 3831, Seq. ID No. 3833, Seq. ID No. 3835, Seq. ID No. 3849, Seq. ID No. 3879, Seq. ID No. 3881, Seq. ID No. 3895, Seq. ID No. 3903, Seq. ID No. 3909, Seq. ID No. 3915, Seq. ID No. 3939, Seq. ID No. 3959, Seq. ID No. 3961, Seq. ID No. 3963, Seq. ID No. 3965, Seq. ID No. 3973, Seq. ID No. 3977, Seq. ID No. 3979, Seq. ID No. 3993, Seq. ID No. 3995, Seq. ID No. 3997, Seq. ID No. 4005, Seq. ID No. 4007, Seq. ID No. 4009, Seq. ID No. 4041, Seq. ID No. 4043, Seq. ID No. 4045, Seq. ID No. 4069, Seq. ID No. 4077, Seq. ID No. 4097, Seq. ID No. 4113, Seq. ID No. 4123, Seq. ID No. 4131, Seq. ID No. 4133, Seq. ID No. 4135, Seq. ID No. 4139, Seq. ID No. 4151, Seq. ID No. 4153, Seq. ID No. 4155, Seq. ID No. 4181, Seq. ID No. 4221, Seq. ID No. 4241, Seq. ID No. 4253, Seq. ID No. 4257, Seq. ID No. 4259, Seq. ID No. 4261, Seq. ID No. 4263, Seq. ID No. 4265, Seq. ID No. 4269, Seq. ID No. 4275, Seq. ID No. 4277, Seq. ID No. 4279, Seq. ID No. 4281, Seq. ID No. 4285, Seq. ID No. 4287, Seq. ID No. 4297, Seq. ID No. 4305, Seq. ID No. 4307, Seq. ID No. 4363, Seq. ID No. 4365, Seq. ID No. 4371, Seq. ID No. 4373, Seq. ID No. 4395, Seq. ID No. 4399, Seq. ID No. 4403, Seq. ID No. 4425, Seq. ID No. 4437, Seq. ID No. 4439, Seq. ID No. 4441, Seq. ID No. 4453, Seq. ID No. 4455, Seq. ID No. 4513, Seq. ID No. 4515, Seq. ID No. 4551, Seq. ID No. 4561, Seq. ID No. 4573, Seq. ID No. 4575, Seq. ID No. 4587, Seq. ID No. 4589, Seq. ID No. 4591, Seq. ID No. 4593, Seq. ID No. 4595, Seq. ID No. 4617, Seq. ID No. 4619, Seq. ID No. 4621, Seq. ID No. 4625, Seq. ID No. 4627, Seq. ID No. 4633, Seq. ID No. 4635, Seq. ID No. 4637, Seq. ID No. 4639, Seq. ID No. 4659, Seq. ID No. 4681, Seq. ID No. 4687, Seq. ID No. 4695, Seq. ID No. 4699, Seq. ID No. 4701, Seq. ID No. 4721, Seq. ID No. 4735, Seq. ID No. 4737, Seq. ID No. 4741, Seq. ID No. 4783, Seq. ID No. 4789, Seq. ID No. 4805, Seq. ID No. 4811, Seq. ID No. 4817, Seq. ID No. 4819, Seq. ID No. 4821, Seq. ID No. 4823, Seq. ID No. 4835, Seq. ID No. 4853, Seq. ID No. 4885, Seq. ID No. 4913, Seq. ID No. 4923, Seq. ID No. 4949, Seq. ID No. 4951, Seq. ID No. 4975, Seq. ID No. 4981, Seq. ID No. 4983, Seq. ID No. 4987, Seq. ID No. 4993, Seq. ID No. 4999, Seq. ID No. 5001, Seq. ID No. 5011, Seq. ID No. 5013, Seq. ID No. 5023, Seq. ID No. 5031, Seq. ID No. 5033, Seq. ID No. 5035, Seq. ID No. 5037, Seq. ID No. 5041, Seq. ID No. 5043, Seq. ID No. 5053, Seq. ID No. 5061, Seq. ID No. 5063, Seq. ID No. 5085, Seq. ID No. 5093, Seq. ID No. 5151, Seq. ID No. 5153, Seq. ID No. 5159, Seq. ID No. 5161, Seq. ID No. 5167, Seq. ID No. 5173, Seq. ID No. 5175, Seq. ID No. 5177, Seq. ID No. 5189, Seq. ID No. 5191, Seq. ID No. 5193, Seq. ID No. 5197, Seq. ID No. 5199, Seq. ID No. 5221, Seq. ID No. 5223, Seq. ID No. 5225, Seq. ID No. 5227, Seq. ID No. 5237, Seq. ID No. 5267, Seq. ID No. 5269, Seq. ID No. 5271, Seq. ID No. 5281, Seq. ID No. 5301, Seq. ID No. 5303, Seq. ID No. 5315, Seq. ID No. 5321, Seq. ID No. 5327, Seq. ID No. 5347, Seq. ID No. 5385, Seq. ID No. 5445, Seq. ID No. 5447, Seq. ID No. 5459, Seq. ID No. 5465, Seq. ID No. 5467, Seq. ID No. 5479, Seq. ID No. 5481, Seq. ID No. 5485, Seq. ID No. 5487, Seq. ID No. 5515, Seq. ID No. 5517, Seq. ID No. 5533, Seq. ID No. 5543, Seq. ID No. 5545, Seq. ID No. 5549, Seq. ID No. 5569, Seq. ID No. 5577, Seq. ID No. 5593, Seq. ID No. 5595, Seq. ID No. 5609, Seq. ID No. 5623, Seq. ID No. 5625, Seq. ID No. 5639, Seq. ID No. 5641, Seq. ID No. 5643, Seq. ID No. 5649, Seq. ID No. 5659, Seq. ID No. 5661, Seq. ID No. 5663, Seq. ID No. 5667, Seq. ID No. 5671, Seq. ID No. 5687, Seq. ID No. 5689, Seq. ID No. 5703, Seq. ID No. 5705, Seq. ID No. 5709, Seq. ID No. 5711, Seq. ID No. 5737, Seq. ID No. 5739, Seq. ID No. 5745, Seq. ID No. 5751, Seq. ID No. 5763, Seq. ID No. 5797, Seq. ID No. 5811, Seq. ID No. 5813, Seq. ID No. 5815, Seq. ID No. 5827, Seq. ID No. 5829, Seq. ID No. 5843, Seq. ID No. 5845, Seq. ID No. 5873, Seq. ID No. 5879, Seq. ID No. 5883, Seq. ID No. 5885, Seq. ID No. 5887, Seq. ID No. 5889, Seq. ID No. 5891, Seq. ID No. 5931, Seq. ID No. 5955, Seq. ID No. 5963, Seq. ID No. 5965, Seq. ID No. 5975, Seq. ID No. 5983, Seq. ID No. 5985, Seq. ID No. 5987, Seq. ID No. 5989, Seq. ID No. 6005, Seq. ID No. 6013, Seq. ID No. 6031, Seq. ID No. 6035, Seq. ID No. 6045, Seq. ID No. 6059, Seq. ID No. 6061, Seq. ID No. 6063, Seq. ID No. 6073, Seq. ID No. 6081, Seq. ID No. 6091, Seq. ID No. 6093, Seq. ID No. 6127, Seq. ID No. 6159, Seq. ID No. 6197, Seq. ID No. 6199, Seq. ID No. 6203, Seq. ID No. 6217, Seq. ID No. 6221, Seq. ID No. 6223, Seq. ID No. 6237, Seq. ID No. 6239, Seq. ID No. 6241, Seq. ID No. 6245, Seq. ID No. 6247, Seq. ID No. 6249, Seq. ID No. 6259, Seq. ID No. 6265, Seq. ID No. 6267, Seq. ID No. 6273, Seq. ID No. 6283, Seq. ID No. 6285, Seq. ID No. 6323, Seq. ID No. 6325, Seq. ID No. 6327, Seq. ID No. 6361, Seq. ID No. 6363, Seq. ID No. 6377, Seq. ID No. 6381, Seq. ID No. 6401, Seq. ID No. 6403, Seq. ID No. 6419, Seq. ID No. 6425, Seq. ID No. 6427, Seq. ID No. 6429, Seq. ID No. 6431, Seq. ID No. 6433, Seq. ID No. 6435, Seq. ID No. 6437, Seq. ID No. 6439, Seq. ID No. 6447, Seq. ID No. 6449, Seq. ID No. 6451, Seq. ID No. 6453, Seq. ID No. 6455, Seq. ID No. 6457, Seq. ID No. 6465, Seq. ID No. 6467, Seq. ID No. 6469, Seq. ID No. 6471, Seq. ID No. 6473, Seq. ID No. 6475, Seq. ID No. 6477, Seq. ID No. 6479, Seq. ID No. 6481, Seq. ID No. 6483, Seq. ID No. 6485, Seq. ID No. 6487, Seq. ID No. 6489, Seq. ID No. 6491, Seq. ID No. 6495, Seq. ID No. 6497, Seq. ID No. 6507, Seq. ID No. 6517, Seq. ID No. 6519, Seq. ID No. 6521, Seq. ID No. 6523, Seq. ID No. 6525, Seq. ID No. 6527, Seq. ID No. 6529, Seq. ID No. 6533, Seq. ID No. 6539, Seq. ID No. 6541, Seq. ID No. 6543, Seq. ID No. 6555, Seq. ID No. 6557, Seq. ID No. 6561, Seq. ID No. 6563, Seq. ID No. 6565, Seq. ID No. 6567, Seq. ID No. 6569, Seq. ID No. 6571, Seq. ID No. 6573, Seq. ID No. 6581, Seq. ID No. 6583, Seq. ID No. 6631, Seq. ID No. 6635, Seq. ID No. 6637, Seq. ID No. 6639, Seq. ID No. 6643, Seq. ID No. 6645, Seq. ID No. 6647, and Seq. ID No. 6649.

In yet another preferred embodiment, the polynucleotide is selected from the Alloiococcus otitidis polynucleotides, which encode polypeptides, identified by Glimmer™ ORF finder program, and the polynucleotide is selected from one of Seq. ID No. 1, Seq. ID No. 5, Seq. ID No. 11, Seq. ID No. 13, Seq. ID No. 15, Seq. ID No. 17, Seq. ID No. 25, Seq. ID No. 27, Seq. ID No. 29, Seq. ID No. 35, Seq. ID No. 37, Seq. ID No. 41, Seq. ID No. 43, Seq. ID No. 47, Seq. ID No. 51, Seq. ID No. 53, Seq. ID No. 59, Seq. ID No. 63, Seq. ID No. 69, Seq. ID No. 73, Seq. ID No. 75, Seq. ID No. 81, Seq. ID No. 83, Seq. ID No. 89, Seq. ID No. 93, Seq. ID No. 97, Seq. ID No. 103, Seq. ID No. 111, Seq. ID No. 121, Seq. ID No. 125, Seq. ID No. 129, Seq. ID No. 135, Seq. ID No. 137, Seq. ID No. 145, Seq. ID No. 149, Seq. ID No. 157, Seq. ID No. 167, Seq. ID No. 173, Seq. ID No. 183, Seq. ID No. 187, Seq. ID No. 189, Seq. ID No. 191, Seq. ID No. 195, Seq. ID No. 197, Seq. ID No. 203, Seq. ID No. 207, Seq. ID No. 215, Seq. ID No. 219, Seq. ID No. 223, Seq. ID No. 225, Seq. ID No. 227, Seq. ID No. 231, Seq. ID No. 233, Seq. ID No. 239, Seq. ID No. 241, Seq. ID No. 247, Seq. ID No. 253, Seq. ID No. 261, Seq. ID No. 265, Seq. ID No. 269, Seq. ID No. 273, Seq. ID No. 275, Seq. ID No. 277, Seq. ID No. 283, Seq. ID No. 291, Seq. ID No. 293, Seq. ID No. 297, Seq. ID No. 301, Seq. ID No. 307, Seq. ID No. 309, Seq. ID No. 313, Seq. ID No. 317, Seq. ID No. 321, Seq. ID No. 325, Seq. ID No. 335, Seq. ID No. 343, Seq. ID No. 345, Seq. ID No. 353, Seq. ID No. 355, Seq. ID No. 361, Seq. ID No. 363, Seq. ID No. 367, Seq. ID No. 375, Seq. ID No. 379, Seq. ID No. 383, Seq. ID No. 389, Seq. ID No. 391, Seq. ID No. 397, Seq. ID No. 405, Seq. ID No. 411, Seq. ID No. 415, Seq. ID No. 417, Seq. ID No. 423, Seq. ID No. 425, Seq. ID No. 427, Seq. ID No. 429, Seq. ID No. 435, Seq. ID No. 437, Seq. ID No. 439, Seq. ID No. 441, Seq. ID No. 445, Seq. ID No. 447, Seq. ID No. 453, Seq. ID No. 461, Seq. ID No. 463, Seq. ID No. 471, Seq. ID No. 485, Seq. ID No. 501, Seq. ID No. 505, Seq. ID No. 511, Seq. ID No. 515, Seq. ID No. 517, Seq. ID No. 521, Seq. ID No. 523, Seq. ID No. 531, Seq. ID No. 533, Seq. ID No. 539, Seq. ID No. 541, Seq. ID No. 543, Seq. ID No. 551, Seq. ID No. 555, Seq. ID No. 561, Seq. ID No. 565, Seq. ID No. 569, Seq. ID No. 575, Seq. ID No. 579, Seq. ID No. 587, Seq. ID No. 593, Seq. ID No. 597, Seq. ID No. 603, Seq. ID No. 605, Seq. ID No. 609, Seq. ID No. 611, Seq. ID No. 613, Seq. ID No. 615, Seq. ID No. 623, Seq. ID No. 627, Seq. ID No. 629, Seq. ID No. 631, Seq. ID No. 635, Seq. ID No. 637, Seq. ID No. 647, Seq. ID No. 649, Seq. ID No. 661, Seq. ID No. 669, Seq. ID No. 673, Seq. ID No. 675, Seq. ID No. 681, Seq. ID No. 683, Seq. ID No. 689, Seq. ID No. 701, Seq. ID No. 703, Seq. ID No. 709, Seq. ID No. 713, Seq. ID No. 729, Seq. ID No. 733, Seq. ID No. 735, Seq. ID No. 737, Seq. ID No. 741, Seq. ID No. 747, Seq. ID No. 751, Seq. ID No. 753, Seq. ID No. 759, Seq. ID No. 765, Seq. ID No. 767, Seq. ID No. 771, Seq. ID No. 781, Seq. ID No. 783, Seq. ID No. 787, Seq. ID No. 791, Seq. ID No. 795, Seq. ID No. 799, Seq. ID No. 807, Seq. ID No. 817, Seq. ID No. 819, Seq. ID No. 823, Seq. ID No. 827, Seq. ID No. 831, Seq. ID No. 835, Seq. ID No. 837, Seq. ID No. 839, Seq. ID No. 847, Seq. ID No. 851, Seq. ID No. 855, Seq. ID No. 859, Seq. ID No. 867, Seq. ID No. 871, Seq. ID No. 875, Seq. ID No. 881, Seq. ID No. 885, Seq. ID No. 889, Seq. ID No. 891, Seq. ID No. 895, Seq. ID No. 901, Seq. ID No. 907, Seq. ID No. 915, Seq. ID No. 919, Seq. ID No. 925, Seq. ID No. 929, Seq. ID No. 935, Seq. ID No. 939, Seq. ID No. 949, Seq. ID No. 951, Seq. ID No. 955, Seq. ID No. 961, Seq. ID No. 965, Seq. ID No. 967, Seq. ID No. 971, Seq. ID No. 985, Seq. ID No. 993, Seq. ID No. 997, Seq. ID No. 1003, Seq. ID No. 1005, Seq. ID No. 1009, Seq. ID No. 1017, Seq. ID No. 1023, Seq. ID No. 1039, Seq. ID No. 1041, Seq. ID No. 1043, Seq. ID No. 1051, Seq. ID No. 1053, Seq. ID No. 1057, Seq. ID No. 1061, Seq. ID No. 1065, Seq. ID No. 1067, Seq. ID No. 1069, Seq. ID No. 1073, Seq. ID No. 1075, Seq. ID No. 1083, Seq. ID No. 1087, Seq. ID No. 1091, Seq. ID No. 1093, Seq. ID No. 1097, Seq. ID No. 1099, Seq. ID No. 1103, Seq. ID No. 1109, Seq. ID No. 1115, Seq. ID No. 1117, Seq. ID No. 1123, Seq. ID No. 1129, Seq. ID No. 1133, Seq. ID No. 1137, Seq. ID No. 1143, Seq. ID No. 1147, Seq. ID No. 1149, Seq. ID No. 1155, Seq. ID No. 1157, Seq. ID No. 1159, Seq. ID No. 1163, Seq. ID No. 1171, Seq. ID No. 1179, Seq. ID No. 1181, Seq. ID No. 1187, Seq. ID No. 1193, Seq. ID No. 1199, Seq. ID No. 1205, Seq. ID No. 1211, Seq. ID No. 1217, Seq. ID No. 1221, Seq. ID No. 1223, Seq. ID No. 1225, Seq. ID No. 1231, Seq. ID No. 1233, Seq. ID No. 1237, Seq. ID No. 1241, Seq. ID No. 1253, Seq. ID No. 1257, Seq. ID No. 1263, Seq. ID No. 1271, Seq. ID No. 1281, Seq. ID No. 1317, Seq. ID No. 1323, Seq. ID No. 1331, Seq. ID No. 1335, Seq. ID No. 1339, Seq. ID No. 1345, Seq. ID No. 1347, Seq. ID No. 1361, Seq. ID No. 1369, Seq. ID No. 1377, Seq. ID No. 1379, Seq. ID No. 1387, Seq. ID No. 1393, Seq. ID No. 1395, Seq. ID No. 1399, Seq. ID No. 1403, Seq. ID No. 1405, Seq. ID No. 1411, Seq. ID No. 1413, Seq. ID No. 1415, Seq. ID No. 1419, Seq. ID No. 1425, Seq. ID No. 1427, Seq. ID No. 1429, Seq. ID No. 1431, Seq. ID No. 1433, Seq. ID No. 1437, Seq. ID No. 1443, Seq. ID No. 1449, Seq. ID No. 1451, Seq. ID No. 1455, Seq. ID No. 1457, Seq. ID No. 1459, Seq. ID No. 1463, Seq. ID No. 1465, Seq. ID No. 1469, Seq. ID No. 1471, Seq. ID No. 1473, Seq. ID No. 1475, Seq. ID No. 1477, Seq. ID No. 1485, Seq. ID No. 1487, Seq. ID No. 1491, Seq. ID No. 1493, Seq. ID No. 1495, Seq. ID No. 1497, Seq. ID No. 1501, Seq. ID No. 1505, Seq. ID No. 1507, Seq. ID No. 1509, Seq. ID No. 1517, Seq. ID No. 1525, Seq. ID No. 1527, Seq. ID No. 1531, Seq. ID No. 1539, Seq. ID No. 1541, Seq. ID No. 1543, Seq. ID No. 1549, Seq. ID No. 1561, Seq. ID No. 1563, Seq. ID No. 1567, Seq. ID No. 1571, Seq. ID No. 1573, Seq. ID No. 1577, Seq. ID No. 1581, Seq. ID No. 1589, Seq. ID No. 1593, Seq. ID No. 1595, Seq. ID No. 1597, Seq. ID No. 1603, Seq. ID No. 1607, Seq. ID No. 1611, Seq. ID No. 1613, Seq. ID No. 1619, Seq. ID No. 1623, Seq. ID No. 1627, Seq. ID No. 1631, Seq. ID No. 1637, Seq. ID No. 1639, Seq. ID No. 1641, Seq. ID No. 1647, Seq. ID No. 1653, Seq. ID No. 1657, Seq. ID No. 1665, Seq. ID No. 1669, Seq. ID No. 1681, Seq. ID No. 1685, Seq. ID No. 1689, Seq. ID No. 1691, Seq. ID No. 1697, Seq. ID No. 1699, Seq. ID No. 1707, Seq. ID No. 1711, Seq. ID No. 1713, Seq. ID No. 1719, Seq. ID No. 1723, Seq. ID No. 1729, Seq. ID No. 1735, Seq. ID No. 1737, Seq. ID No. 1741, Seq. ID No. 1747, Seq. ID No. 1751, Seq. ID No. 1757, Seq. ID No. 1759, Seq. ID No. 1761, Seq. ID No. 1771, Seq. ID No. 1777, Seq. ID No. 1785, Seq. ID No. 1789, Seq. ID No. 1791, Seq. ID No. 1797, Seq. ID No. 1801, Seq. ID No. 1803, Seq. ID No. 1805, Seq. ID No. 1811, Seq. ID No. 1817, Seq. ID No. 1819, Seq. ID No. 1821, Seq. ID No. 1825, Seq. ID No. 1829, Seq. ID No. 1837, Seq. ID No. 1843, Seq. ID No. 1845, Seq. ID No. 1847, Seq. ID No. 1849, Seq. ID No. 1851, Seq. ID No. 1855, Seq. ID No. 1859, Seq. ID No. 1863, Seq. ID No. 1865, Seq. ID No. 1867, Seq. ID No. 1871, Seq. ID No. 1873, Seq. ID No. 1877, Seq. ID No. 1885, Seq. ID No. 1887, Seq. ID No. 1889, Seq. ID No. 1895, Seq. ID No. 1897, Seq. ID No. 1899, Seq. ID No. 1903, Seq. ID No. 1905, Seq. ID No. 1913, Seq. ID No. 1919, Seq. ID No. 1923, Seq. ID No. 1925, Seq. ID No. 1931, Seq. ID No. 1935, Seq. ID No. 1937, Seq. ID No. 1943, Seq. ID No. 1945, Seq. ID No. 1949, Seq. ID No. 1953, Seq. ID No. 1957, Seq. ID No. 1959, Seq. ID No. 1961, Seq. ID No. 1965, Seq. ID No. 1967, Seq. ID No. 1971, Seq. ID No. 1975, Seq. ID No. 1979, Seq. ID No. 1983, Seq. ID No. 1987, Seq. ID No. 1989, Seq. ID No. 1991, Seq. ID No. 1999, Seq. ID No. 2001, Seq. ID No. 2003, Seq. ID No. 2009, Seq. ID No. 2015, Seq. 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ID No. 4859, Seq. ID No. 4861, Seq. ID No. 4865, Seq. ID No. 4867, Seq. ID No. 4875, Seq. ID No. 4877, Seq. ID No. 4879, Seq. ID No. 4881, Seq. ID No. 4883, Seq. ID No. 4885, Seq. ID No. 4887, Seq. ID No. 4893, Seq. ID No. 4899, Seq. ID No. 4901, Seq. ID No. 4903, Seq. ID No. 4905, Seq. ID No. 4907, Seq. ID No. 4911, Seq. ID No. 4915, Seq. ID No. 4917, Seq. ID No. 4919, Seq. ID No. 4921, Seq. ID No. 4927, Seq. ID No. 4931, Seq. ID No. 4935, Seq. ID No. 4939, Seq. ID No. 4941, Seq. ID No. 4943, Seq. ID No. 4945, Seq. ID No. 4947, Seq. ID No. 4953, Seq. ID No. 4957, Seq. ID No. 4959, Seq. ID No. 4963, Seq. ID No. 4965, Seq. ID No. 4969, Seq. ID No. 4971, Seq. ID No. 4973, Seq. ID No. 4979, Seq. ID No. 4985, Seq. ID No. 4989, Seq. ID No. 4991, Seq. ID No. 4995, Seq. ID No. 4997, Seq. ID No. 5001, Seq. ID No. 5007, Seq. ID No. 5009, Seq. ID No. 5017, Seq. ID No. 5021, Seq. ID No. 5027, Seq. ID No. 5029, Seq. ID No. 5039, Seq. ID No. 5047, Seq. ID No. 5051, Seq. ID No. 5053, Seq. ID No. 5055, Seq. ID No. 5059, Seq. ID No. 5061, Seq. ID No. 5069, Seq. ID No. 5077, Seq. ID No. 5079, Seq. ID No. 5081, Seq. ID No. 5083, Seq. ID No. 5087, Seq. ID No. 5091, Seq. ID No. 5093, Seq. ID No. 5097, Seq. ID No. 5103, Seq. ID No. 5105, Seq. ID No. 5109, Seq. ID No. 5111, Seq. ID No. 5113, Seq. ID No. 5115, Seq. ID No. 5117, Seq. ID No. 5127, Seq. ID No. 5141, Seq. ID No. 5145, Seq. ID No. 5149, Seq. ID No. 5153, Seq. ID No. 5157, Seq. ID No. 5165, Seq. ID No. 5169, Seq. ID No. 5171, Seq. ID No. 5177, Seq. ID No. 5183, Seq. ID No. 5185, Seq. ID No. 5187, Seq. ID No. 5193, Seq. ID No. 5195, Seq. ID No. 5201, Seq. ID No. 5203, Seq. ID No. 5205, Seq. ID No. 5209, Seq. ID No. 5211, Seq. ID No. 5215, Seq. ID No. 5219, Seq. ID No. 5227, Seq. ID No. 5231, Seq. ID No. 5235, Seq. ID No. 5237, Seq. ID No. 5239, Seq. ID No. 5243, Seq. ID No. 5245, Seq. ID No. 5247, Seq. ID No. 5253, Seq. ID No. 5255, Seq. ID No. 5257, Seq. ID No. 5261, Seq. ID No. 5263, Seq. ID No. 5271, Seq. ID No. 5275, Seq. ID No. 5283, Seq. ID No. 5291, Seq. ID No. 5299, Seq. ID No. 5305, Seq. ID No. 5309, Seq. ID No. 5311, Seq. ID No. 5313, Seq. ID No. 5319, Seq. ID No. 5323, Seq. ID No. 5325, Seq. ID No. 5335, Seq. ID No. 5337, Seq. ID No. 5341, Seq. ID No. 5345, Seq. ID No. 5351, Seq. ID No. 5355, Seq. ID No. 5363, Seq. ID No. 5365, Seq. ID No. 5367, Seq. ID No. 5371, Seq. ID No. 5373, Seq. ID No. 5381, Seq. ID No. 5383, Seq. ID No. 5387, Seq. ID No. 5389, Seq. ID No. 5391, Seq. ID No. 5393, Seq. ID No. 5395, Seq. ID No. 5397, Seq. ID No. 5399, Seq. ID No. 5401, Seq. ID No. 5403, Seq. ID No. 5409, Seq. ID No. 5411, Seq. ID No. 5415, Seq. ID No. 5417, Seq. ID No. 5419, Seq. ID No. 5421, Seq. ID No. 5423, Seq. ID No. 5427, Seq. ID No. 5431, Seq. ID No. 5433, Seq. ID No. 5439, Seq. ID No. 5441, Seq. ID No. 5443, Seq. ID No. 5447, Seq. ID No. 5449, Seq. ID No. 5451, Seq. ID No. 5453, Seq. ID No. 5455, Seq. ID No. 5457, Seq. ID No. 5473, Seq. ID No. 5477, Seq. ID No. 5483, Seq. ID No. 5487, Seq. ID No. 5491, Seq. ID No. 5495, Seq. ID No. 5499, Seq. ID No. 5503, Seq. ID No. 5507, Seq. ID No. 5509, Seq. ID No. 5513, Seq. ID No. 5527, Seq. ID No. 5531, Seq. ID No. 5537, Seq. ID No. 5539, Seq. ID No. 5541, Seq. ID No. 5547, Seq. ID No. 5553, Seq. ID No. 5557, Seq. ID No. 5559, Seq. ID No. 5563, Seq. ID No. 5567, Seq. ID No. 5571, Seq. ID No. 5575, Seq. ID No. 5581, Seq. ID No. 5585, Seq. ID No. 5591, Seq. ID No. 5599, Seq. ID No. 5601, Seq. ID No. 5605, Seq. ID No. 5615, Seq. ID No. 5621, Seq. ID No. 5629, Seq. ID No. 5631, Seq. ID No. 5637, Seq. ID No. 5647, Seq. ID No. 5651, Seq. ID No. 5655, Seq. ID No. 5657, Seq. ID No. 5661, Seq. ID No. 5665, Seq. ID No. 5669, Seq. ID No. 5671, Seq. ID No. 5673, Seq. ID No. 5679, Seq. ID No. 5685, Seq. ID No. 5693, Seq. ID No. 5697, Seq. ID No. 5699, Seq. ID No. 5701, Seq. ID No. 5707, Seq. ID No. 5715, Seq. ID No. 5717, Seq. ID No. 5723, Seq. ID No. 5727, Seq. ID No. 5735, Seq. ID No. 5739, Seq. ID No. 5749, Seq. ID No. 5751, Seq. ID No. 5755, Seq. ID No. 5761, Seq. ID No. 5771, Seq. ID No. 5775, Seq. ID No. 5777, Seq. ID No. 5779, Seq. ID No. 5783, Seq. ID No. 5789, Seq. ID No. 5795, Seq. ID No. 5801, Seq. ID No. 5803, Seq. ID No. 5809, Seq. ID No. 5815, Seq. ID No. 5819, Seq. ID No. 5825, Seq. ID No. 5833, Seq. ID No. 5835, Seq. ID No. 5841, Seq. ID No. 5845, Seq. ID No. 5847, Seq. ID No. 5849, Seq. ID No. 5851, Seq. ID No. 5853, Seq. ID No. 5855, Seq. ID No. 5859, Seq. ID No. 5865, Seq. ID No. 5871, Seq. ID No. 5875, Seq. ID No. 5877, Seq. ID No. 5881, Seq. ID No. 5887, Seq. ID No. 5891, Seq. ID No. 5895, Seq. ID No. 5897, Seq. ID No. 5901, Seq. ID No. 5903, Seq. ID No. 5911, Seq. ID No. 5913, Seq. ID No. 5915, Seq. ID No. 5917, Seq. ID No. 5919, Seq. ID No. 5929, Seq. ID No. 5931, Seq. ID No. 5933, Seq. ID No. 5937, Seq. ID No. 5941, Seq. ID No. 5943, Seq. ID No. 5947, Seq. ID No. 5951, Seq. ID No. 5953, Seq. ID No. 5955, Seq. ID No. 5957, Seq. ID No. 5961, Seq. ID No. 5969, Seq. ID No. 5973, Seq. ID No. 5979, Seq. ID No. 5981, Seq. ID No. 5985, Seq. ID No. 5989, Seq. ID No. 5993, Seq. ID No. 6001, Seq. ID No. 6003, Seq. ID No. 6011, Seq. ID No. 6015, Seq. ID No. 6017, Seq. ID No. 6021, Seq. ID No. 6027, Seq. ID No. 6029, Seq. ID No. 6033, Seq. ID No. 6035, Seq. ID No. 6041, Seq. ID No. 6043, Seq. ID No. 6053, Seq. ID No. 6057, Seq. ID No. 6065, Seq. ID No. 6071, Seq. ID No. 6079, Seq. ID No. 6085, Seq. ID No. 6089, Seq. ID No. 6095, Seq. ID No. 6097, Seq. ID No. 6101, Seq. ID No. 6103, Seq. ID No. 6111, Seq. ID No. 6113, Seq. ID No. 6117, Seq. ID No,. 6123, Seq. ID No. 6125, Seq. ID No. 6129, Seq. ID No. 6131, Seq. ID No. 6133, Seq. ID No. 6141, Seq. ID No. 6145, Seq. ID No. 6149, Seq. ID No. 6157, Seq. ID No. 6165, Seq. ID No. 6169, Seq. ID No. 6171, Seq. ID No. 6175, Seq. ID No. 6177, Seq. ID No. 6181, Seq. ID No. 6187, Seq. ID No. 6195, Seq. ID No. 6201, Seq. ID No. 6209, Seq. ID No. 6213, Seq. ID No. 6215, Seq. ID No. 6219, Seq. ID No. 6233, Seq. ID No. 6235, Seq. ID No. 6243, Seq. ID No. 6249, Seq. ID No. 6251, Seq. ID No. 6257, Seq. ID No. 6261, Seq. ID No. 6263, Seq. ID No. 6271, Seq. ID No. 6275, Seq. ID No. 6277, Seq. ID No. 6281, Seq. ID No. 6287, Seq. ID No. 6297, Seq. ID No. 6299, Seq. ID No. 6305, Seq. ID No. 6311, Seq. ID No. 6315, Seq. ID No. 6321, Seq. ID No. 6323, Seq. ID No. 6327, Seq. ID No. 6331, Seq. ID No. 6333, Seq. ID No. 6337, Seq. ID No. 6339, Seq. ID No. 6341, Seq. ID No. 6343, Seq. ID No. 6345, Seq. ID No. 6353, Seq. ID No. 6357, Seq. ID No. 6359, Seq. ID No. 6361, Seq. ID No. 6367, Seq. ID No. 6369, Seq. ID No. 6373, Seq. ID No. 6375, Seq. ID No. 6377, Seq. ID No. 6379, Seq. ID No. 6389, Seq. ID No. 6395, Seq. ID No. 6399, Seq. ID No. 6403, Seq. ID No. 6407, Seq. ID No. 6411, Seq. ID No. 6413, Seq. ID No. 6417, Seq. ID No. 6423, Seq. ID No. 6433, Seq. ID No. 6437, Seq. ID. No. 6439, Seq. ID No. 6445, Seq. ID No. 6449, Seq. ID No. 6451, Seq. ID No. 6457, Seq. ID No. 6459, Seq. ID No. 6461, Seq. ID No. 6463, Seq. ID No. 6477, Seq. ID No. 6481, Seq. ID No. 6483, Seq. ID No. 6487, Seq. ID No. 6489, Seq. ID No. 6491, Seq. ID No. 6493, Seq. ID No. 6495, Seq. ID No. 6503, Seq. ID No. 6505, Seq. ID No. 6511, Seq. ID No. 6515, Seq. ID No. 6519, Seq. ID No. 6523, Seq. ID No. 6525, Seq. ID No. 6529, Seq. ID No. 6531, Seq. ID No. 6533, Seq. ID No. 6537, Seq. ID No. 6545, Seq. ID No. 6551, Seq. ID No. 6553, Seq. ID No. 6559, Seq. ID No. 6563, Seq. ID No. 6567, Seq. ID No. 6577, Seq. ID No. 6579, Seq. ID No. 6583, Seq. ID No. 6585, Seq. ID No. 6587, Seq. ID No. 6589, Seq. ID No. 6603, Seq. ID No. 6605, Seq. ID No. 6609, Seq. ID No. 6613, Seq. ID No. 6615, Seq. ID No. 6617, Seq. ID No. 6621, Seq. ID No. 6623, Seq. ID No. 6627, Seq. ID No. 6629, Seq. ID No. 6633, and Seq. ID No. 6639.

In yet another preferred embodiment, the polynucleotide is selected from the Alloiococcus otitidis polynucleotides, which encode polypeptides, identified by GeneMark™ ORF finder program, and the polynucleotide is selected from one of Seq. ID No. 1, Seq. ID No. 3, Seq. ID No. 11, Seq. ID No. 13, Seq. ID No. 15, Seq. ID No. 17, Seq. ID No. 25, Seq. ID No. 27, Seq. ID No. 29, Seq. ID No. 35, Seq. ID No. 37, Seq. ID No. 39, Seq. ID No. 41, Seq. ID No. 43, Seq. ID No. 45, Seq. ID No. 49, Seq. ID No. 53, Seq. ID No. 57, Seq. ID No. 61, Seq. ID No. 69, Seq. ID No. 71, Seq. ID No. 75, Seq. ID No. 81, Seq. ID No. 83, Seq. ID No. 89, Seq. ID No. 95, Seq. ID No. 101, Seq. ID No. 111, Seq. ID No. 119, Seq. ID No. 125, Seq. ID No. 129, Seq. ID No. 135, Seq. ID No. 137, Seq. ID No. 141, Seq. ID No. 147, Seq. ID No. 151, Seq. ID No. 155, Seq. ID No. 167, Seq. ID No. 171, Seq. ID No. 181, Seq. ID No. 185, Seq. ID No. 187, Seq. ID No. 189, Seq. ID No. 191, Seq. ID No. 195, Seq. ID No. 199, Seq. ID No. 207, Seq. ID No. 213, Seq. ID No. 219, Seq. ID No. 221, Seq. ID No. 225, Seq. ID No. 227, Seq. ID No. 229, Seq. ID No. 233, Seq. ID No. 239, Seq. ID No. 241, Seq. ID No. 243, Seq. ID No. 253, Seq. ID No. 261, Seq. ID No. 263, Seq. ID No. 267, Seq. ID No. 273, Seq. ID No. 275, Seq. ID No. 277, Seq. ID No. 279, Seq. ID No. 291, Seq. ID No. 293, Seq. ID No. 295, Seq. ID No. 299, Seq. ID No. 303, Seq. ID No. 309, Seq. ID No. 311, Seq. ID No. 315, Seq. ID No. 319, Seq. ID No. 323, Seq. ID No. 331, Seq. ID No. 341, Seq. ID No. 345, Seq. ID No. 351, Seq. ID No. 355, Seq. ID No. 361, Seq. ID No. 363, Seq. ID No. 365, Seq. ID No. 375, Seq. ID No. 379, Seq. ID No. 381, Seq. ID No. 383, Seq. ID No. 389, Seq. ID No. 391, Seq. ID No. 395, Seq. ID No. 399, Seq. ID No. 405, Seq. ID No. 409, Seq. ID No. 413, Seq. ID No. 417, Seq. ID No. 421, Seq. ID No. 423, Seq. ID No. 425, Seq. ID No. 427, Seq. ID No. 429, Seq. ID No. 435, Seq. ID No. 437, Seq. ID No. 439, Seq. ID No. 441, Seq. ID No. 443, Seq. ID No. 445, Seq. ID No. 447, Seq. ID No. 449, Seq. ID No. 459, Seq. ID No. 465, Seq. ID No. 485, Seq. ID No. 501, Seq. ID No. 505, Seq. ID No. 511, Seq. ID No. 513, Seq. ID No. 517, Seq. ID No. 519, Seq. ID No. 523, Seq. ID No. 529, Seq. ID No. 533, Seq. ID No. 535, Seq. ID No. 541, Seq. ID No. 543, Seq. ID No. 551, Seq. ID No. 553, Seq. ID No. 559, Seq. ID No. 563, Seq. ID No. 569, Seq. ID No. 575, Seq. ID No. 579, Seq. ID No. 583, Seq. ID No. 591, Seq. ID No. 595, Seq. ID No. 601, Seq. ID No. 605, Seq. ID No. 607, Seq. ID No. 611, Seq. ID No. 613, Seq. ID No. 615, Seq. ID No. 621, Seq. ID No. 627, Seq. ID No. 629, Seq. ID No. 633, Seq. ID No. 635, Seq. ID No. 637, Seq. ID No. 643, Seq. ID No. 649, Seq. ID No. 651, Seq. ID No. 655, Seq. ID No. 657, Seq. ID No. 669, Seq. ID No. 671, Seq. ID No. 675, Seq. ID No. 681, Seq. ID No. 683, Seq. ID No. 685, Seq. ID No. 693, Seq. ID No. 703, Seq. ID No. 705, Seq. ID No. 711, Seq. ID No. 725, Seq. ID No. 731, Seq. ID No. 735, Seq. ID No. 737, Seq. ID No. 741, Seq. ID No. 743, Seq. ID No. 749, Seq. ID No. 753, Seq. ID No. 759, Seq. ID No. 773, Seq. ID No. 781, Seq. ID No. 783, Seq. ID No. 785, Seq. ID No. 789, Seq. ID No. 793, Seq. ID No. 797, Seq. ID No. 803, Seq. ID No. 815, Seq. ID No. 819, Seq. ID No. 821, Seq. ID No. 827, Seq. ID No. 831, Seq. ID No. 833, Seq. ID No. 835, Seq. ID No. 837, Seq. ID No. 841, Seq. ID No. 843, Seq. ID No. 849, Seq. ID No. 851, Seq. ID No. 853, Seq. ID No. 857, Seq. ID No. 865, Seq. ID No. 869, Seq. ID No. 873, Seq. ID No. 877, Seq. ID No. 883, Seq. ID No. 887, Seq. ID No. 891, Seq. ID No. 895, Seq. ID No. 901, Seq. ID No. 907, Seq. ID No. 911, Seq. ID No. 917, Seq. ID No. 921, Seq. ID No. 927, Seq. ID No. 935, Seq. ID No. 939, Seq. ID No. 945, Seq. ID No. 951, Seq. ID No. 953, Seq. ID No. 959, Seq. ID No. 963, Seq. ID No. 967, Seq. ID No. 969, Seq. ID No. 977, Seq. ID No. 989, Seq. ID No. 995, Seq. ID No. 999, Seq. ID No. 1005, Seq. ID No. 1007, Seq. ID No. 1015, Seq. ID No. 1021, Seq. ID No. 1035, Seq. ID No. 1041, Seq. ID No. 1043, Seq. ID No. 1049, Seq. ID No. 1053, Seq. ID No. 1057, Seq. ID No. 1059, Seq. ID No. 1063, Seq. ID No. 1067, Seq. ID No. 1069, Seq. ID No. 1071, Seq. ID No. 1075, Seq. ID No. 1083, Seq. ID No. 1085, Seq. ID No. 1089, Seq. ID No. 1093, Seq. ID No. 1097, Seq. ID No. 1099, Seq. ID No. 1101, Seq. ID No. 1109, Seq. ID No. 1113, Seq. ID No. 1117, Seq. ID No. 1121, Seq. ID No. 1129, Seq. ID No. 1133, Seq. ID No. 1137, Seq. ID No. 1141, Seq. ID No. 1145, Seq. ID No. 1149, Seq. ID No. 1155, Seq. ID No. 1157, Seq. ID No. 1159, Seq. ID No. 1163, Seq. ID No. 1171, Seq. ID No. 1173, Seq. ID No. 1175, Seq. ID No. 1181, Seq. ID No. 1185, Seq. ID No. 1189, Seq. ID No. 1199, Seq. ID No. 1205, Seq. ID No. 1209, Seq. ID No. 1215, Seq. ID No. 1219, Seq. ID No. 1223, Seq. ID No. 1225, Seq. ID No. 1233, Seq. ID No. 1235, Seq. ID No. 1241, Seq. ID No. 1251, Seq. ID No. 1255, Seq. ID No. 1261, Seq. ID No. 1271, Seq. ID No. 1281, Seq. ID No. 1315, Seq. ID No. 1323, Seq. ID No. 1331, Seq. ID No. 1333, Seq. ID No. 1339, Seq. ID No. 1345, Seq. ID No. 1347, Seq. ID No. 1355, Seq. ID No. 1357, Seq. ID No. 1369, Seq. ID No. 1373, Seq. ID No. 1387, Seq. ID No. 1391, Seq. ID No. 1395, Seq. ID No. 1397, Seq. ID No. 1403, Seq. ID No. 1405, Seq. ID No. 1407, Seq. ID No. 1413, Seq. ID No. 1415, Seq. ID No. 1417, Seq. ID No. 1425, Seq. ID No. 1427, Seq. ID No. 1429, Seq. ID No. 1431, Seq. ID No. 1433, Seq. ID No. 1435, Seq. ID No. 1439, Seq. ID No. 1441, Seq. ID No. 1451, Seq. ID No. 1453, Seq. ID No. 1459, Seq. ID No. 1461, Seq. ID No. 1469, Seq. ID No. 1471, Seq. ID No. 1473, Seq. ID No. 1475, Seq. ID No. 1477, Seq. ID No. 1483, Seq. ID No. 1487, Seq. ID No. 1489, Seq. ID No. 1493, Seq. ID No. 1495, Seq. ID No. 1497, Seq. ID No. 1501, Seq. ID No. 1503, Seq. ID No. 1507, Seq. ID No. 1509, Seq. ID No. 1517; Seq. ID No. 1521, Seq. ID No. 1527, Seq. ID No. 1531, Seq. ID No. 1537, Seq. ID No. 1541, Seq. ID No. 1543, Seq. ID No. 1549, Seq. ID No. 1561, Seq. ID No. 1563, Seq. ID No. 1565, Seq. ID No. 1569, Seq. ID No. 1573, Seq. ID No. 1575, Seq. ID No. 1581, Seq. ID No. 1587, Seq. ID No. 1591, Seq. ID No. 1595, Seq. ID No. 1597, Seq. ID No. 1605, Seq. ID No. 1609, Seq. ID No. 1613, Seq. ID No. 1619, Seq. ID No. 1623, Seq. ID No. 1627, Seq. ID No. 1629, Seq. ID No. 1635, Seq. ID No. 1641, Seq. ID No. 1647, Seq. ID No. 1651, Seq. ID No. 1657, Seq. ID No. 1659, Seq. ID No. 1667, Seq. ID No. 1669, Seq. ID No. 1679, Seq. ID No. 1683, Seq. ID No. 1687, Seq. ID No. 1691, Seq. ID No. 1697, Seq. ID No. 1699, Seq. ID No. 1701, Seq. ID No. 1707, Seq. ID No. 1709, Seq. ID No. 1713, Seq. ID No. 1717, Seq. ID No. 1721, Seq. ID No. 1725, Seq. ID No. 1735, Seq. ID No. 1737, Seq. ID No. 1739, Seq. ID No. 1743, Seq. ID No. 1745, Seq. ID No. 1749, Seq. ID No. 1755, Seq. ID No. 1769, Seq. ID No. 1773, Seq. ID No. 1777, Seq. ID No. 1785, Seq. ID No. 1789, Seq. ID No. 1791, Seq. ID No. 1797, Seq. ID No. 1799, Seq. ID No. 1803, Seq. ID No. 1805, Seq. ID No. 1807, Seq. ID No. 1817, Seq. ID No. 1819, Seq. ID No. 1821, Seq. ID No. 1825, Seq. ID No. 1827, Seq. ID No. 1831, Seq. ID No. 1835, Seq. ID No. 1841, Seq. ID No. 1845, Seq. ID No. 1847, Seq. ID No. 1849, Seq. ID No. 1851, Seq. ID No. 1855, Seq. ID No. 1859, Seq. ID No. 1861, Seq. ID No. 1865, Seq. ID No. 1867, Seq. ID No. 1871, Seq. ID No. 1873, Seq. ID No. 1877, Seq. ID No. 1879, Seq. ID No. 1887, Seq. ID No. 1889, Seq. ID No. 1895, Seq. ID No. 1897, Seq. ID No. 1899, Seq. ID No. 1901, Seq. ID No. 1905, Seq. ID No. 1909, Seq. ID No. 1917, Seq. ID No. 1921, Seq. ID No. 1925, Seq. ID No. 1931, Seq. ID No. 1933, Seq. ID No. 1937, Seq. ID No. 1939, Seq. ID No. 1945, Seq. ID No. 1947, Seq. ID No. 1951, Seq. ID No. 1955, Seq. ID No. 1959, Seq. ID No. 1961, Seq. ID No. 1965, Seq. ID No. 1967, Seq. ID No. 1969, Seq. ID No. 1973, Seq. ID No. 1977, Seq. ID No. 1979, Seq. ID No. 1983, Seq. ID No. 1989, Seq. ID No. 1991, Seq. 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ID No. 4865, Seq. ID No. 4867, Seq. ID No. 4875, Seq. ID No. 4879, Seq. ID No. 4881, Seq. ID No. 4883, Seq. ID No. 4885, Seq. ID No. 4887, Seq. ID No. 4893, Seq. ID No. 4899, Seq. ID No. 4901, Seq. ID No. 4903, Seq. ID No. 4905, Seq. ID No. 4907, Seq. ID No. 4909, Seq. ID No. 4915, Seq. ID No. 4917, Seq. ID No. 4919, Seq. ID No. 4921, Seq. ID No. 4925, Seq. ID No. 4929, Seq. ID No. 4933, Seq. ID No. 4937, Seq. ID No. 4941, Seq. ID No. 4943, Seq. ID No. 4945, Seq. ID No. 4947, Seq. ID No. 4953, Seq. ID No. 4955, Seq. ID No. 4959, Seq. ID No. 4961, Seq. ID No. 4965, Seq. ID No. 4967, Seq. ID No. 4971, Seq. ID No. 4973, Seq. ID No. 4977, Seq. ID No. 4985, Seq. ID No. 4989, Seq. ID No. 4991, Seq. ID No. 4995, Seq. ID No. 4997, Seq. ID No. 5005, Seq. ID No. 5009, Seq. ID No. 5015, Seq. ID No. 5019, Seq. ID No. 5025, Seq. ID No. 5029, Seq. ID No. 5037, Seq. ID No. 5045, Seq. ID No. 5049, Seq. ID No. 5053, Seq. ID No. 5055, Seq. ID No. 5059, Seq. ID No. 5061, Seq. ID No. 5065, Seq. ID No. 5071, Seq. ID No. 5073, Seq. ID No. 5079, Seq. ID No. 5081, Seq. ID No. 5083, Seq. ID No. 5087, Seq. ID No. 5089, Seq. ID No. 5093, Seq. ID No. 5095, Seq. ID No. 5103, Seq. ID No. 5105, Seq. ID No. 5107, Seq. ID No. 5111, Seq. ID No. 5113, Seq. ID No. 5115, Seq. ID No. 5117, Seq. ID No. 5119, Seq. ID No. 5141, Seq. ID No. 5143, Seq. ID No. 5147, Seq. ID No. 5153, Seq. ID No. 5155, Seq. ID No. 5163, Seq. ID No. 5169, Seq. ID No. 5171, Seq. ID No. 5173, Seq. ID No. 5179, Seq. ID No. 5185, Seq. ID No. 5187, Seq. ID No. 5193, Seq. ID No. 5195, Seq. ID No. 5201, Seq. ID No. 5203, Seq. ID No. 5205, Seq. ID No. 5209, Seq. ID No. 5211, Seq. ID No. 5213, Seq. ID No. 5217, Seq. ID No. 5225, Seq. ID No. 5231, Seq. ID No. 5233, Seq. ID No. 5237, Seq. ID No. 5239, Seq. ID No. 5245, Seq. ID No. 5247, Seq. ID No. 5249, Seq. ID No. 5255, Seq. ID No. 5257, Seq. ID No. 5259, Seq. ID No. 5263, Seq. ID No. 5269, Seq. ID No. 5273, Seq. ID No. 5283, Seq. ID No. 5289, Seq. ID No. 5293, Seq. ID No. 5307, Seq. ID No. 5311, Seq. ID No. 5313, Seq. ID No. 5315, Seq. ID No. 5323, Seq. ID No. 5325, Seq. ID No. 5335, Seq. ID No. 5337, Seq. ID No. 5339, Seq. ID No. 5345, Seq. ID No. 5347, Seq. ID No. 5349, Seq. ID No. 5353, Seq. ID No. 5361, Seq. ID No. 5365, Seq. ID No. 5367, Seq. ID No. 5369, Seq. ID No. 5373, Seq. ID No. 5375, Seq. ID No. 5387, Seq. ID No. 5389, Seq. ID No. 5391, Seq. ID No. 5393, Seq. ID No. 5395, Seq. ID No. 5397, Seq. ID No. 5399, Seq. ID No. 5401, Seq. ID No. 5403, Seq. ID No. 5405, Seq. ID No. 5411, Seq. ID No. 5415, Seq. ID No. 5417, Seq. ID No. 5419, Seq. ID No. 5421, Seq. ID No. 5423, Seq. ID No. 5429, Seq. ID No. 5433, Seq. ID No. 5441, Seq. ID No. 5443, Seq. ID No. 5445, Seq. ID No. 5449, Seq. ID No. 5451, Seq. ID No. 5453, Seq. ID No. 5455, Seq. ID No. 5457, Seq. ID No. 5469, Seq. ID No. 5475, Seq. ID No. 5483, Seq. ID No. 5485, Seq. ID No. 5489, Seq. ID No. 5493, Seq. ID No. 5499, Seq. ID No. 5501, Seq. ID No. 5505, Seq. ID No. 5509, Seq. ID No. 5511, Seq. ID No. 5523, Seq. ID No. 5529, Seq. ID No. 5535, Seq. ID No. 5539, Seq. ID No. 5541, Seq. ID No. 5547, Seq. ID No. 5551, Seq. ID No. 5555, Seq. ID No. 5559, Seq. ID No. 5561, Seq. ID No. 5565, Seq. ID No. 5571, Seq. ID No. 5573, Seq. ID No. 5579, Seq. ID No. 5583, Seq. ID No. 5589, Seq. ID No. 5599, Seq. ID No. 5601, Seq. ID No. 5603, Seq. ID No. 5613, Seq. ID No. 5621, Seq. ID No. 5627, Seq. ID No. 5631, Seq. ID No. 5635, Seq. ID No. 5645, Seq. ID No. 5651, Seq. ID No. 5653, Seq. ID No. 5657, Seq. ID No. 5661, Seq. ID No. 5663, Seq. ID No. 5665, Seq. ID No. 5669, Seq. ID No. 5671, Seq. ID No. 5673, Seq. ID No. 5675, Seq. ID No. 5681, Seq. ID No. 5693, Seq. ID No. 5695, Seq. ID No. 5699, Seq. ID No. 5701, Seq. ID No. 5707, Seq. ID No. 5713, Seq. ID No. 5717, Seq. ID No. 5723, Seq. ID No. 5725, Seq. ID No. 5731, Seq. ID No. 5737, Seq. ID No. 5747, Seq. ID No. 5751, Seq. ID No. 5755, Seq. ID No. 5759, Seq. ID No. 5771, Seq. ID No. 5773, Seq. ID No. 5777, Seq. ID No. 5779, Seq. ID No. 5781, Seq. ID No. 5785, Seq. ID No. 5793, Seq. ID No. 5799, Seq. ID No. 5805, Seq. ID No. 5811, Seq. ID No. 5815, Seq. ID No. 5817, Seq. ID No. 5823, Seq. ID No. 5831, Seq. ID No. 5835, Seq. ID No. 5839, Seq. ID No. 5843, Seq. ID No. 5847, Seq. ID No. 5849, Seq. ID No. 5851, Seq. ID No. 5853, Seq. ID No. 5855, Seq. ID No. 5857, Seq. ID No. 5861, Seq. ID No. 5867, Seq. ID No. 5875, Seq. ID No. 5877, Seq. ID No. 5881, Seq. ID No. 5889, Seq. ID No. 5895, Seq. ID No. 5897, Seq. ID No. 5901, Seq. ID No. 5903, Seq. ID No. 5907, Seq. ID No. 5913, Seq. ID No. 5915, Seq. ID No. 5917, Seq. ID No. 5919, Seq. ID No. 5925, Seq. ID No. 5931, Seq. ID No. 5933, Seq. ID No. 5935, Seq. ID No. 5941, Seq. ID No. 5943, Seq. ID No. 5945, Seq. ID No. 5949, Seq. ID No. 5955, Seq. ID No. 5957, Seq. ID No. 5958, Seq. ID No. 5967, Seq. ID No. 5971, Seq. ID No. 5975, Seq. ID No. 5977, Seq. ID No. 5981, Seq. ID No. 5983, Seq. ID No. 5985, Seq. ID No. 5989, Seq. ID No. 5991, Seq. ID No. 5995, Seq. ID No. 5997, Seq. ID No. 6003, Seq. ID No. 6005, Seq. ID No. 6007, Seq. ID No. 6015, Seq. ID No. 6017, Seq. ID No. 6019, Seq. ID No. 6023, Seq. ID No. 6029, Seq. ID No. 6033, Seq. ID No. 6035, Seq. ID No. 6037, Seq. ID No. 6043, Seq. ID No. 6049, Seq. ID No. 6055, Seq. ID No. 6065, Seq. ID No. 6069, Seq. ID No. 6075, Seq. ID No. 6081, Seq. ID No. 6083, Seq. ID No. 6087, Seq. ID No. 6095, Seq. ID No. 6097, Seq. ID No. 6099, Seq. ID No. 6103, Seq. ID No. 6105, Seq. ID No. 6113, Seq. ID No. 6115, Seq. ID No. 6119, Seq. ID No. 6125, Seq. ID No. 6127, Seq. ID No. 6129, Seq. ID No. 6131, Seq. ID No. 6133, Seq. ID No. 6141, Seq. ID No. 6143, Seq. ID No. 6147, Seq. ID No. 6153, Seq. ID No. 6165, Seq. ID No. 6169, Seq. ID No. 6171, Seq. ID No. 6173, Seq. ID No. 6177, Seq. ID No. 6179, Seq. ID No. 6187, Seq. ID No. 6193, Seq. ID No. 6201, Seq. ID No. 6207, Seq. ID No. 6211, Seq. ID No. 6215, Seq. ID No. 6219, Seq. ID No. 6231, Seq. ID No. 6235, Seq. ID No. 6243, Seq. ID No. 6247, Seq. ID No. 6251, Seq. ID No. 6255, Seq. ID No. 6261, Seq. ID No. 6263, Seq. ID No. 6269, Seq. ID No. 6275, Seq. ID No. 6277, Seq. ID No. 6279, Seq. ID No. 6287, Seq. ID No. 6291, Seq. ID No. 6299, Seq. ID No. 6305, Seq. ID No. 6307, Seq. ID No. 6313, Seq. ID No. 6315, Seq. ID No. 6321, Seq. ID No. 6323, Seq. ID No. 6325, Seq. ID No. 6331, Seq. ID No. 6335, Seq. ID No. 6339, Seq. ID No. 6341, Seq. ID No. 6343, Seq. ID No. 6345, Seq. ID No. 6347, Seq. ID No. 6355, Seq. ID No. 6359, Seq. ID No. 6361, Seq. ID No. 6365, Seq. ID No. 6369, Seq. ID No. 6371, Seq. ID No. 6375, Seq. ID No. 6377, Seq. ID No. 6379, Seq. ID No. 6387, Seq. ID No. 6391, Seq. ID No. 6397, Seq. ID No. 6401, Seq. ID No. 6405, Seq. ID No. 6409, Seq. ID No. 6413, Seq. ID No. 6417, Seq. ID No. 6419, Seq. ID No. 6423, Seq. ID No. 6429, Seq. ID No. 6433, Seq. ID No. 6435, Seq. ID No. 6439, Seq. ID No. 6445, Seq. ID No. 6447, Seq. ID No. 6451, Seq. ID No. 6455, Seq. ID No. 6459, Seq. ID No. 6461, Seq. ID No. 6463, Seq. ID No. 6475, Seq. ID No. 6481, Seq. ID No. 6483, Seq. ID No. 6485, Seq. ID No. 6487, Seq. ID No. 6489, Seq. ID No. 6491, Seq. ID No. 6493, Seq. ID No. 6495, Seq. ID No. 6499, Seq. ID No. 6505, Seq. ID No. 6509, Seq. ID No. 6513, Seq. ID No. 6519, Seq. ID No. 6521, Seq. ID No. 6525, Seq. ID No. 6527, Seq. ID No. 6531, Seq. ID No. 6533, Seq. ID No. 6535, Seq. ID No. 6545, Seq. ID No. 6551, Seq. ID No. 6553, Seq. ID No. 6559, Seq. ID No. 6561, Seq. ID No. 6563, Seq. ID No. 6565, Seq. ID No. 6567, Seq. ID No. 6569, Seq. ID No. 6575, Seq. ID No. 6579, Seq. ID No. 6583, Seq. ID No. 6585, Seq. ID No. 6591, Seq. ID No. 6595, Seq. ID No. 6605, Seq. ID No. 6607, Seq. ID No. 6611, Seq. ID No. 6615, Seq. ID No. 6617, Seq. ID No. 6619, Seq. ID No. 6623, Seq. ID No. 6625, Seq. ID No. 6629, Seq. ID No. 6633, Seq. ID No. 6635, Seq. ID No. 6641, and Seq. ID No. 6647.

In another preferred embodiment, the invention comprises an isolated polynucleotide of the Alloiococcus otitidis genomic sequence encoding a polypeptide, which has been identified by the Applicants' assignee's ORF finder program that searches for an ATG, GTG or TTG Start codon between “Stop-Stop” region, and the polynucleotide is selected from one of Seq. ID No. 1, Seq. ID No. 5, Seq. ID No. 11, Seq. ID No. 13, Seq. ID No. 15, Seq. ID No. 17, Seq. ID No. 19, Seq. ID No. 21, Seq. ID No. 23, Seq. ID No. 27, Seq. ID No. 29, Seq. ID No. 31, Seq. ID No. 35, Seq. ID No. 37, Seq. ID No. 41, Seq. ID No. 43, Seq. ID No. 45, Seq. ID No. 47, Seq. ID No. 49, Seq. ID No. 51, Seq. ID No. 53, Seq. ID No. 55, Seq. ID No. 57, Seq. ID No. 59, Seq. ID No. 65, Seq. ID No. 67, Seq. ID No. 75, Seq. ID No. 77, Seq. ID No. 79, Seq. ID No. 81, Seq. ID No. 83, Seq. ID No. 89, Seq. ID No. 91, Seq. ID No. 93, Seq. ID No. 97, Seq. ID No. 99, Seq. ID No. 103, Seq. ID No. 105, Seq. ID No. 107, Seq. ID No. 109, Seq. ID No. 111, Seq. ID No. 113, Seq. ID No. 115, Seq. ID No. 117, Seq. ID No. 119, Seq. ID No. 121, Seq. ID No. 127, Seq. ID No. 129, Seq. ID No. 131, Seq. ID No. 133, Seq. ID No. 135, Seq. ID No. 137, Seq. ID No. 139, Seq. ID No. 143, Seq. ID No. 145, Seq. ID No. 147, Seq. ID No. 149, Seq. ID No. 153, Seq. ID No. 155, Seq. ID No. 157, Seq. ID No. 159, Seq. ID No. 161, Seq. ID No. 163, Seq. ID No. 165, Seq. ID No. 167, Seq. ID No. 169, Seq. ID No. 171, Seq. ID No. 175, Seq. ID No. 177, Seq. ID No. 179, Seq. ID No. 181, Seq. ID No. 183, Seq. ID No. 187, Seq. ID No. 191, Seq. ID No. 193, Seq. ID No. 195, Seq. ID No. 201, Seq. ID No. 205, Seq. ID No. 207, Seq. ID No. 215, Seq. ID No. 219, Seq. ID No. 221, Seq. ID No. 223, Seq. ID No. 225, Seq. ID No. 227, Seq. ID No. 231, Seq. ID No. 233, Seq. ID No. 239, Seq. ID No. 243, Seq. ID No. 245, Seq. ID No. 247, Seq. ID No. 253, Seq. ID No. 257, Seq. ID No. 259, Seq. ID No. 261, Seq. ID No. 263, Seq. ID No. 265, Seq. ID No. 267, Seq. ID No. 269, Seq. ID No. 273, Seq. ID No. 277, Seq. ID No. 279, Seq. ID No. 281, Seq. ID No. 283, Seq. ID No. 291, Seq. ID No. 293, Seq. ID No. 297, Seq. ID No. 301, Seq. ID No. 305, Seq. ID No. 307, Seq. ID No. 309, Seq. ID No. 313, Seq. ID No. 317, Seq. ID No. 321, Seq. ID No. 323, Seq. ID No. 325, Seq. ID No. 331, Seq. ID No. 333, Seq. ID No. 335, Seq. ID No. 337, Seq. ID No. 339, Seq. ID No. 343, Seq. ID No. 345, Seq. ID No. 347, Seq. ID No. 349, Seq. ID No. 353, Seq. ID No. 355, Seq. ID No. 357, Seq. ID No. 359, Seq. ID No. 361, Seq. ID No. 363, Seq. ID No. 365, Seq. ID No. 367, Seq. ID No. 369, Seq. ID No. 371, Seq. ID No. 375, Seq. ID No. 377, Seq. ID No. 379, Seq. ID No. 383, Seq. ID No. 385, Seq. ID No. 387, Seq. ID No. 389, Seq. ID No. 391, Seq. ID No. 393, Seq. ID No. 397, Seq. ID No. 401, Seq. ID No. 403, Seq. ID No. 405, Seq. ID No. 407, Seq. ID No. 409, Seq. ID No. 415, Seq. ID No. 423, Seq. ID No. 425, Seq. ID No. 427, Seq. ID No. 429, Seq. ID No. 431, Seq. ID No. 433, Seq. ID No. 435, Seq. ID No. 437, Seq. ID No. 439, Seq. ID No. 441, Seq. ID No. 443, Seq. ID No. 445, Seq. ID No. 447, Seq. ID No. 451, Seq. ID No. 453, Seq. ID No. 455, Seq. ID No. 457, Seq. ID No. 461, Seq. ID No. 463, Seq. ID No. 467, Seq. ID No. 469, Seq. ID No. 471, Seq. ID No. 473, Seq. ID No. 475, Seq. ID No. 477, Seq. ID No. 479, Seq. ID No. 481, Seq. ID No. 483, Seq. ID No. 485, Seq. ID No. 489, Seq. ID No. 491, Seq. ID No. 493, Seq. ID No. 495, Seq. ID No. 501, Seq. ID No. 505, Seq. ID No. 507, Seq. ID No. 511, Seq. ID No. 515, Seq. ID No. 517, Seq. ID No. 523, Seq. ID No. 529, Seq. ID No. 531, Seq. ID No. 533, Seq. ID No. 537, Seq. ID No. 539, Seq. ID No. 543, Seq. ID No. 547, Seq. ID No. 549, Seq. ID No. 551, Seq. ID No. 553, Seq. ID No. 555, Seq. ID No. 557, Seq. ID No. 559, Seq. ID No. 561, Seq. ID No. 565, Seq. ID No. 569, Seq. ID No. 571, Seq. ID No. 573, Seq. ID No. 575, Seq. ID No. 579, Seq. ID No. 581, Seq. ID No. 585, Seq. ID No. 587, Seq. ID No. 589, Seq. ID No. 591, Seq. ID No. 593, Seq. ID No. 595, Seq. ID No. 597, Seq. ID No. 599, Seq. ID No. 601, Seq. ID No. 603, Seq. ID No. 605, Seq. ID No. 609, Seq. ID No. 613, Seq. ID No. 615, Seq. ID No. 617, Seq. ID No. 619, Seq. ID No. 621, Seq. ID No. 623, Seq. ID No. 625, Seq. ID No. 627, Seq. ID No. 635, Seq. ID No. 637, Seq. ID No. 643, Seq. ID No. 645, Seq. ID No. 647, Seq. ID No. 649, Seq. ID No. 655, Seq. ID No. 663, Seq. ID No. 665, Seq. ID No. 667, Seq. ID No. 669, Seq. ID No. 675, Seq. ID No. 681, Seq. ID No. 683, Seq. ID No. 687, Seq. ID No. 689, Seq. ID No. 691, Seq. ID No. 695, Seq. ID No. 697, Seq. ID No. 699, Seq. ID No. 701, Seq. ID No. 703, Seq. ID No. 705, Seq. ID No. 707, Seq. ID No. 709, Seq. ID No. 713, Seq. ID No. 725, Seq. ID No. 727, Seq. ID No. 729, Seq. ID No. 731, Seq. ID No. 733, Seq. ID No. 735, Seq. ID No. 739, Seq. ID No. 741, Seq. ID No. 745, Seq. ID No. 747, Seq. ID No. 749, Seq. ID No. 751, Seq. ID No. 753, Seq. ID No. 759, Seq. ID No. 763, Seq. ID No. 765, Seq. ID No. 773, Seq. ID No. 775, Seq. ID No. 781, Seq. ID No. 783, Seq. ID No. 787, Seq. ID No. 793, Seq. ID No. 795, Seq. ID No. 799, Seq. ID No. 801, Seq. ID No. 805, Seq. ID No. 807, Seq. ID No. 809, Seq. ID No. 811, Seq. ID No. 813, Seq. ID No. 815, Seq. ID No. 817, Seq. ID No. 819, Seq. ID No. 821, Seq. ID No. 823, Seq. ID No. 827, Seq. ID No. 829, Seq. ID No. 831, Seq. ID No. 835, Seq. ID No. 837, Seq. ID No. 839, Seq. ID No. 843, Seq. ID No. 845, Seq. ID No. 847, Seq. ID No. 855, Seq. ID No. 859, Seq. ID No. 861, Seq. ID No. 865, Seq. ID No. 867, Seq. ID No. 871, Seq. ID No. 873, Seq. ID No. 875, Seq. ID No. 877, Seq. ID No. 879, Seq. ID No. 881, Seq. ID No. 885, Seq. ID No. 895, Seq. ID No. 897, Seq. ID No. 899, Seq. ID No. 901, Seq. ID No. 903, Seq. ID No. 905, Seq. ID No. 907, Seq. ID No. 909, Seq. ID No. 913, Seq. ID No. 915, Seq. ID No. 921, Seq. ID No. 923, Seq. ID No. 925, Seq. ID No. 931, Seq. ID No. 933, Seq. ID No. 935, Seq. ID No. 937, Seq. ID No. 939, Seq. ID No. 941, Seq. ID No. 943, Seq. ID No. 947, Seq. ID No. 949, Seq. ID No. 951, Seq. ID No. 953, Seq. ID No. 955, Seq. ID No. 957, Seq. ID No. 961, Seq. ID No. 963, Seq. ID No. 965, Seq. ID No. 967, Seq. ID No. 969, Seq. ID No. 971, Seq. ID No. 973, Seq. ID No. 975, Seq. ID No. 981, Seq. ID No. 983, Seq. ID No. 985, Seq. ID No. 987, Seq. ID No. 989, Seq. ID No. 991, Seq. ID No. 993, Seq. ID No. 995, Seq. ID No. 997, Seq. ID No. 1001, Seq. ID No. 1003, Seq. ID No. 1005, Seq. ID No. 1007, Seq. ID No. 1009, Seq. ID No. 1017, Seq. ID No. 1019, Seq. ID No. 1023, Seq. ID No. 1025, Seq. ID No. 1027, Seq. ID No. 1039, Seq. ID No. 1041, Seq. ID No. 1043, Seq. ID No. 1045, Seq. ID No. 1047, Seq. ID No. 1049, Seq. ID No. 1051, Seq. ID No. 1057, Seq. ID No. 1059, Seq. ID No. 1061, Seq. ID No. 1065, Seq. ID No. 1069, Seq. ID No. 1075, Seq. ID No. 1077, Seq. ID No. 1079, Seq. ID No. 1081, Seq. ID No. 1083, Seq. ID No. 1085, Seq. ID No. 1087, Seq. ID No. 1091, Seq. ID No. 1093, Seq. ID No. 1095, Seq. ID No. 1097, Seq. ID No. 1099, Seq. ID No. 1101, Seq. ID No. 1103, Seq. ID No. 1107, Seq. ID No. 1109, Seq. ID No. 1111, Seq. ID No. 1113, Seq. ID No. 1115, Seq. ID No. 1119, Seq. ID No. 1121, Seq. ID No. 1123, Seq. ID No. 1125, Seq. ID No. 1127, Seq. ID No. 1129, Seq. ID No. 1131, Seq. ID No. 1137, Seq. ID No. 1139, Seq. ID No. 1141, Seq. ID No. 1143, Seq. ID No. 1145, Seq. ID No. 1147, Seq. ID No. 1149, Seq. ID No. 1151, Seq. ID No. 1153, Seq. ID No. 1155, Seq. ID No. 1157, Seq. ID No. 1159, Seq. ID No. 1161, Seq. ID No. 1163, Seq. ID No. 1171, Seq. ID No. 1175, Seq. ID No. 1177, Seq. ID No. 1179, Seq. ID No. 1181, Seq. ID No. 1187, Seq. ID No. 1191, Seq. ID No. 1193, Seq. ID No. 1195, Seq. ID No. 1197, Seq. ID No. 1201, Seq. ID No. 1203, Seq. ID No. 1205, Seq. ID No. 1207, Seq. ID No. 1211, Seq. ID No. 1213, Seq. ID No. 1215, Seq. ID No. 1217, Seq. ID No. 1221, Seq. ID No. 1223, Seq. ID No. 1225, Seq. ID No. 1231, Seq. ID No. 1233, Seq. 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ID No. 2005, Seq. ID No. 2007, Seq. ID No. 2015, Seq. ID No. 2019, Seq. ID No. 2021, Seq. ID No. 2025, Seq. ID No. 2027, Seq. ID No. 2029, Seq. ID No. 2031, Seq. ID No. 2035, Seq. ID No. 2037, Seq. ID No. 2041, Seq. ID No. 2043, Seq. ID No. 2045, Seq. ID No. 2047, Seq. ID No. 2053, Seq. ID No. 2055, Seq. ID No. 2059, Seq. ID No. 2063, Seq. ID No. 2065, Seq. ID No. 2067, Seq. ID No. 2069, Seq. ID No. 2071, Seq. ID No. 2073, Seq. ID No. 2075, Seq. ID No. 2077, Seq. ID No. 2079, Seq. ID No. 2081, Seq. ID No. 2083, Seq. ID No. 2085, Seq. ID No. 2089, Seq. ID No. 2091, Seq. ID No. 2093, Seq. ID No. 2097, Seq. ID No. 2099, Seq. ID No. 2101, Seq. ID No. 2103, Seq. ID No. 2107, Seq. ID No. 2109, Seq. ID No. 2111, Seq. ID No. 2115, Seq. ID No. 2117, Seq. ID No. 2119, Seq. ID No. 2125, Seq. ID No. 2127, Seq. ID No. 2129, Seq. ID No. 2131, Seq. ID No. 2133, Seq. ID No. 2135, Seq. ID No. 2137, Seq. ID No. 2141, Seq. ID No. 2143, Seq. ID No. 2145, Seq. ID No. 2149, Seq. ID No. 2151, Seq. ID No. 2153, Seq. ID No. 2155, Seq. ID No. 2157, Seq. ID No. 2159, Seq. ID No. 2161, Seq. ID No. 2165, Seq. ID No. 2167, Seq. ID No. 2169, Seq. ID No. 2179, Seq. ID No. 2181, Seq. ID No. 2183, Seq. ID No. 2189, Seq. ID No. 2191, Seq. ID No. 2195, Seq. ID No. 2197, Seq. ID No. 2199, Seq. ID No. 2201, Seq. ID No. 2203, Seq. ID No. 2205, Seq. ID No. 2207, Seq. ID No. 2209, Seq. ID No. 2211, Seq. ID No. 2213, Seq. ID No. 2215, Seq. ID No. 2217, Seq. ID No. 2221, Seq. ID No. 2223, Seq. ID No. 2227, Seq. ID No. 2229, Seq. ID No. 2235, Seq. ID No. 2241, Seq. ID No. 2245, Seq. ID No. 2247, Seq. ID No. 2251, Seq. ID No. 2253, Seq. ID No. 2257, Seq. ID No. 2259, Seq. ID No. 2261, Seq. ID No. 2263, Seq. ID No. 2265, Seq. ID No. 2267, Seq. ID No. 2269, Seq. ID No. 2275, Seq. ID No. 2277, Seq. ID No. 2279, Seq. ID No. 2285, Seq. ID No. 2287, Seq. ID No. 2297, Seq. ID No. 2299, Seq. ID No. 2301, Seq. ID No. 2309, Seq. ID No. 2311, Seq. ID No. 2315, Seq. ID No. 2327, Seq. ID No. 2329, Seq. ID No. 2333, Seq. ID No. 2343, Seq. ID No. 2345, Seq. ID No. 2349, Seq. ID No. 2351, Seq. ID No. 2357, Seq. ID No. 2363, Seq. ID No. 2365, Seq. ID No. 2367, Seq. ID No. 2369, Seq. ID No. 2371, Seq. ID No. 2373, Seq. ID No. 2375, Seq. ID No. 2379, Seq. ID No. 2381, Seq. ID No. 2385, Seq. ID No. 2387, Seq. ID No. 2391, Seq. ID No. 2393, Seq. ID No. 2395, Seq. ID No. 2397, Seq. ID No. 2399, Seq. ID No. 2401, Seq. ID No. 2405, Seq. ID No. 2409, Seq. ID No. 2413, Seq. ID No. 2415, Seq. ID No. 2417, Seq. ID No. 2421, Seq. ID No. 2423, Seq. ID No. 2425, Seq. ID No. 2427, Seq. ID No. 2429, Seq. ID No. 2435, Seq. ID No. 2437, Seq. ID No. 2445, Seq. ID No. 2447, Seq. ID No. 2449, Seq. ID No. 2451, Seq. ID No. 2453, Seq. ID No. 2455, Seq. ID No. 2457, Seq. ID No. 2459, Seq. ID No. 2461, Seq. ID No. 2463, Seq. ID No. 2465, Seq. ID No. 2469, Seq. ID No. 2471, Seq. ID No. 2475, Seq. ID No. 2481, Seq. ID No. 2483, Seq. ID No. 2485, Seq. ID No. 2491, Seq. ID No. 2493, Seq. ID No. 2495, Seq. 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ID No. 2799, Seq. ID No. 2801, Seq. ID No. 2803, Seq. ID No. 2807, Seq. ID No. 2809, Seq. ID No. 2813, Seq. ID No. 2815, Seq. ID No. 2821, Seq. ID No. 2823, Seq. ID No. 2827, Seq. ID No. 2829, Seq. ID No. 2831, Seq. ID No. 2833, Seq. ID No. 2839, Seq. ID No. 2841, Seq. ID No. 2843, Seq. ID No. 2845, Seq. ID No. 2847, Seq. ID No. 2855, Seq. ID No. 2861, Seq. ID No. 2863, Seq. ID No. 2865, Seq. ID No. 2867, Seq. ID No. 2869, Seq. ID No. 2871, Seq. ID No. 2877, Seq. ID No. 2881, Seq. ID No. 2883, Seq. ID No. 2885, Seq. ID No. 2887, Seq. ID No. 2891, Seq. ID No. 2893, Seq. ID No. 2895, Seq. ID No. 2899, Seq. ID No. 2901, Seq. ID No. 2907, Seq. ID No. 2915, Seq. ID No. 2917, Seq. ID No. 2919, Seq. ID No. 2921, Seq. ID No. 2923, Seq. ID No. 2927, Seq. ID No. 2931, Seq. ID No. 2933, Seq. ID No. 2935, Seq. ID No. 2943, Seq. ID No. 2945, Seq. ID No. 2951, Seq. ID No. 2953, Seq. ID No. 2957, Seq. ID No. 2959, Seq. ID No. 2961, Seq. ID No. 2963, Seq. ID No. 2965, Seq. ID No. 2967, Seq. ID No. 2971, Seq. ID No. 2973, Seq. ID No. 2975, Seq. ID No. 2977, Seq. ID No. 2979, Seq. ID No. 2983, Seq. ID No. 2985, Seq. ID No. 2987, Seq. ID No. 2991, Seq. ID No. 2993, Seq. ID No. 2999, Seq. ID No. 3001, Seq. ID No. 3005, Seq. ID No. 3009, Seq. ID No. 3011, Seq. ID No. 3015, Seq. ID No. 3017, Seq. ID No. 3019, Seq. ID No. 3021, Seq. ID No. 3027, Seq. ID No. 3033, Seq. ID No. 3035, Seq. ID No. 3037, Seq. ID No. 3039, Seq. ID No. 3043, Seq. ID No. 3045, Seq. ID No. 3047, Seq. ID No. 3049, Seq. ID No. 3051, Seq. ID No. 3053, Seq. ID No. 3055, Seq. ID No. 3057, Seq. ID No. 3059, Seq. ID No. 3067, Seq. ID No. 3069, Seq. ID No. 3071, Seq. ID No. 3079, Seq. ID No. 3083, Seq. ID No. 3085, Seq. ID No. 3087, Seq. ID No. 3091, Seq. ID No. 3093, Seq. ID No. 3099, Seq. ID No. 3101, Seq. ID No. 3103, Seq. ID No. 3109, Seq. ID No. 3111, Seq. ID No. 3115, Seq. ID No. 3117, Seq. ID No. 3119, Seq. ID No. 3121, Seq. ID No. 3123, Seq. ID No. 3125, Seq. ID No. 3129, Seq. ID No. 3131, Seq. 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ID No. 5263, Seq. ID No. 5265, Seq. ID No. 5267, Seq. ID No. 5277, Seq. ID No. 5279, Seq. ID No. 5281, Seq. ID No. 5285, Seq. ID No. 5287, Seq. ID No. 5291, Seq. ID No. 5295, Seq. ID No. 5297, Seq. ID No. 5299, Seq. ID No. 5301, Seq. ID No. 5303, Seq. ID No. 5305, Seq. ID No. 5307, Seq. ID No. 5309, Seq. ID No. 5311, Seq. ID No. 5313, Seq. ID No. 5317, Seq. ID No. 5319, Seq. ID No. 5321, Seq. ID No. 5323, Seq. ID No. 5327, Seq. ID No. 5329, Seq. ID No. 5331, Seq. ID No. 5333, Seq. ID No. 5335, Seq. ID No. 5337, Seq. ID No. 5343, Seq. ID No. 5345, Seq. ID No. 5349, Seq. ID No. 5351, Seq. ID No. 5357, Seq. ID No. 5359, Seq. ID No. 5365, Seq. ID No. 5367, Seq. ID No. 5373, Seq. ID No. 5377, Seq. ID No. 5379, Seq. ID No. 5381, Seq. ID No. 5383, Seq. ID No. 5387, Seq. ID No. 5389, Seq. ID No. 5391, Seq. ID No. 5393, Seq. ID No. 5397, Seq. ID No. 5399, Seq. ID No. 5401, Seq. ID No. 5403, Seq. ID No. 5405, Seq. ID No. 5407, Seq. ID No. 5409, Seq. ID No. 5411, Seq. ID No. 5415, Seq. ID No. 5417, Seq. ID No. 5419, Seq. ID No. 5421, Seq. ID No. 5423, Seq. ID No. 5425, Seq. ID No. 5427, Seq. ID No. 5431, Seq. ID No. 5433, Seq. ID No. 5435, Seq. ID No. 5437, Seq. ID No. 5439, Seq. ID No. 5441, Seq. ID No. 5443, Seq. ID No. 5447, Seq. ID No. 5449, Seq. ID No. 5451, Seq. ID No. 5453, Seq. ID No. 5455, Seq. ID No. 5457, Seq. ID No. 5467, Seq. ID No. 5471, Seq. ID No. 5473, Seq. ID No. 5477, Seq. ID No. 5479, Seq. ID No. 5481, Seq. ID No. 5491, Seq. ID No. 5493, Seq. ID No. 5495, Seq. ID No. 5499, Seq. ID No. 5503, Seq. ID No. 5509, Seq. ID No. 5513, Seq. ID No. 5515, Seq. ID No. 5517, Seq. ID No. 5519, Seq. ID No. 5521, Seq. ID No. 5527, Seq. ID No. 5529, Seq. ID No. 5531, Seq. ID No. 5533, Seq. ID No. 5537, Seq. ID No. 5539, Seq. ID No. 5541, Seq. ID No. 5543, Seq. ID No. 5545, Seq. ID No. 5547, Seq. ID No. 5549, Seq. ID No. 5551, Seq. ID No. 5553, Seq. ID No. 5557, Seq. ID No. 5559, Seq. ID No. 5563, Seq. ID No. 5567, Seq. ID No. 5569, Seq. ID No. 5575, Seq. ID No. 5577, Seq. ID No. 5581, Seq. ID No. 5583, Seq. ID No. 5585, Seq. ID No. 5589, Seq. ID No. 5591, Seq. ID No. 5593, Seq. ID No. 5595, Seq. ID No. 5599, Seq. ID No. 5601, Seq. ID No. 5607, Seq. ID No. 5613, Seq. ID No. 5615, Seq. ID No. 5617, Seq. ID No. 5619, Seq. ID No. 5621, Seq. ID No. 5625, Seq. ID No. 5627, Seq. ID No. 5629, Seq. ID No. 5631, Seq. ID No. 5637, Seq. ID No. 5639, Seq. ID No. 5641, Seq. ID No. 5645, Seq. ID No. 5647, Seq. ID No. 5649, Seq. ID No. 5651, Seq. ID No. 5655, Seq. ID No. 5657, Seq. ID No. 5661, Seq. ID No. 5665, Seq. ID No. 5667, Seq. ID No. 5669, Seq. ID No. 5677, Seq. ID No. 5679, Seq. ID No. 5683, Seq. ID No. 5685, Seq. ID No. 5687, Seq. ID No. 5689, Seq. ID No. 5691, Seq. ID No. 5693, Seq. ID No. 5697, Seq. ID No. 5699, Seq. ID No. 5701, Seq. ID No. 5703, Seq. ID No. 5705, Seq. ID No. 5707, Seq. ID No. 5711, Seq. ID No. 5713, Seq. ID No. 5715, Seq. ID No. 5717, Seq. ID No. 5719, Seq. ID No. 5721, Seq. ID No. 5723, Seq. ID No. 5725, Seq. ID No. 5727, Seq. ID No. 5735, Seq. ID No. 5739, Seq. ID No. 5741, Seq. ID No. 5743, Seq. ID No. 5745, Seq. ID No. 5747, Seq. ID No. 5749, Seq. ID No. 5751, Seq. ID No. 5753, Seq. ID No. 5755, Seq. ID No. 5757, Seq. ID No. 5759, Seq. ID No. 5761, Seq. ID No. 5769, Seq. ID No. 5771, Seq. ID No. 5777, Seq. ID No. 5779, Seq. ID No. 5783, Seq. ID No. 5787, Seq. ID No. 5791, Seq. ID No. 5795, Seq. ID No. 5799, Seq. ID No. 5801, Seq. ID No. 5807, Seq. ID No. 5809, Seq. ID No. 5813, Seq. ID No. 5815, Seq. ID No. 5819, Seq. ID No. 5821, Seq. ID No. 5823, Seq. ID No. 5825, Seq. ID No. 5827, Seq. ID No. 5829, Seq. ID No. 5831, Seq. ID No. 5833, Seq. ID No. 5835, Seq. ID No. 5837, Seq. ID No. 5839, Seq. ID No. 5841, Seq. ID No. 5845, Seq. ID No. 5847, Seq. ID No. 5849, Seq. ID No. 5851, Seq. ID No. 5855, Seq. ID No. 5857, Seq. ID No. 5859, Seq. ID No. 5861, Seq. ID No. 5863, Seq. ID No. 5865, Seq. ID No. 5869, Seq. ID No. 5871, Seq. ID No. 5873, Seq. ID No. 5875, Seq. ID No. 5879, Seq. ID No. 5881, Seq. ID No. 5883, Seq. ID No. 5889, Seq. ID No. 5895, Seq. ID No. 5897, Seq. ID No. 5901, Seq. ID No. 5903, Seq. ID No. 5911, Seq. ID No. 5913, Seq. ID No. 5915, Seq. ID No. 5917, Seq. ID No. 5919, Seq. ID No. 5927, Seq. ID No. 5929, Seq. ID No. 5933, Seq. ID No. 5935, Seq. ID No. 5937, Seq. ID No. 5941, Seq. ID No. 5945, Seq. ID No. 5947, Seq. ID No. 5951, Seq. ID No. 5959, Seq. ID No. 5961, Seq. ID No. 5963, Seq. ID No. 5965, Seq. ID No. 5967, Seq. ID No. 5969, Seq. ID No. 5971, Seq. ID No. 5973, Seq. ID No. 5977, Seq. ID No. 5979, Seq. ID No. 5981, Seq. ID No. 5985, Seq. ID No. 5987, Seq. ID No. 5989, Seq. ID No. 5991, Seq. ID No. 5993, Seq. ID No. 5995, Seq. ID No. 5999, Seq. ID No. 6001, Seq. ID No. 6003, Seq. ID No. 6009, Seq. ID No. 6011, Seq. ID No. 6013, Seq. ID No. 6015, Seq. ID No. 6017, Seq. ID No. 6025, Seq. ID No. 6027, Seq. ID No. 6029, Seq. ID No. 6031, Seq. ID No. 6033, Seq. ID No. 6035, Seq. ID No. 6039, Seq. ID No. 6041, Seq. ID No. 6043, Seq. ID No. 6045, Seq. ID No. 6049, Seq. ID No. 6051, Seq. ID No. 6053, Seq. ID No. 6055, Seq. ID No. 6057, Seq. ID No. 6061, Seq. ID No. 6063, Seq. ID No. 6065, Seq. ID No. 6069, Seq. ID No. 6071, Seq. ID No. 6073, Seq. ID No. 6077, Seq. ID No. 6079, Seq. ID No. 6085, Seq. ID No. 6087, Seq. ID No. 6089, Seq. ID No. 6093, Seq. ID No. 6095, Seq. ID No. 6101, Seq. ID No. 6103, Seq. ID No. 6109, Seq. ID No. 6111, Seq. ID No. 6117, Seq. ID No. 6121, Seq. ID No. 6123, Seq. ID No. 6129, Seq. ID No. 6131, Seq. ID No. 6133, Seq. ID No. 6135, Seq. ID No. 6137, Seq. ID No. 6139, Seq. ID No. 6141, Seq. ID No. 6145, Seq. ID No. 6151, Seq. ID No. 6155, Seq. ID No. 6157, Seq. ID No. 6159, Seq. ID No. 6165, Seq. ID No. 6167, Seq. ID No. 6169, Seq. ID No. 6171, Seq. ID No. 6175, Seq. ID No. 6177, Seq. ID No. 6181, Seq. ID No. 6187, Seq. ID No. 6193, Seq. ID No. 6195, Seq. ID No. 6197, Seq. ID No. 6199, Seq. ID No. 6201, Seq. ID No. 6209, Seq. ID No. 6213, Seq. ID No. 6215, Seq. ID No. 6217, Seq. ID No. 6219, Seq. ID No. 6231, Seq. ID No. 6233, Seq. ID No. 6235, Seq. ID No. 6239, Seq. ID No. 6241, Seq. ID No. 6243, Seq. ID No. 6249, Seq. ID No. 6257, Seq. ID No. 6259, Seq. ID No. 6261, Seq. ID No. 6263, Seq. ID No. 6267, Seq. ID No. 6269, Seq. ID No. 6271, Seq. ID No. 6275, Seq. ID No. 6277, Seq. ID No. 6279, Seq. ID No. 6281, Seq. ID No. 6283, Seq. ID No. 6285, Seq. ID No. 6287, Seq. ID No. 6293, Seq. ID No. 6295, Seq. ID No. 6297, Seq. ID No. 6299, Seq. ID No. 6305, Seq. ID No. 6309, Seq. ID No. 6311, Seq. ID No. 6315, Seq. ID No. 6317, Seq. ID No. 6319, Seq. ID No. 6321, Seq. ID No. 6323, Seq. ID No. 6325, Seq. ID No. 6327, Seq. ID No. 6329, Seq. ID No. 6331, Seq. ID No. 6335, Seq. ID No. 6337, Seq. ID No. 6341, Seq. ID No. 6345, Seq. ID No. 6349, Seq. ID No. 6351, Seq. ID No. 6353, Seq. ID No. 6359, Seq. ID No. 6361, Seq. ID No. 6367, Seq. ID No. 6369, Seq. ID No. 6371, Seq. ID No. 6373, Seq. ID No. 6375, Seq. ID No. 6377, Seq. ID No. 6379, Seq. ID No. 6381, Seq. ID No. 6385, Seq. ID No. 6389, Seq. ID No. 6393, Seq. ID No. 6395, Seq. ID No. 6399, Seq. ID No. 6409, Seq. ID No. 6411, Seq. ID No. 6413, Seq. ID No. 6417, Seq. ID No. 6421, Seq. ID No. 6423, Seq. ID No. 6425, Seq. ID No. 6427, Seq. ID No. 6429, Seq. ID No. 6431, Seq. ID No. 6441, Seq. ID No. 6443, Seq. ID No. 6445, Seq. ID No. 6451, Seq. ID No. 6453, Seq. ID No. 6459, Seq. ID No. 6461, Seq. ID No. 6463, Seq. ID No. 6465, Seq. ID No. 6467, Seq. ID No. 6469, Seq. ID No. 6471, Seq. ID No. 6473, Seq. ID No. 6479, Seq. ID No. 6483, Seq. ID No. 6493, Seq. ID No. 6495, Seq. ID No. 6497, Seq. ID No. 6501, Seq. ID No. 6503, Seq. ID No. 6505, Seq. ID No. 6507, Seq. ID No. 6511, Seq. ID No. 6517, Seq. ID No. 6523, Seq. ID No. 6525, Seq. ID No. 6535, Seq. ID No. 6537, Seq. ID No. 6539, Seq. ID No. 6541, Seq. ID No. 6543, Seq. ID No. 6545, Seq. ID No. 6547, Seq. ID No. 6549, Seq. ID No. 6551, Seq. ID No. 6553, Seq. ID No. 6555, Seq. ID No. 6557, Seq. ID No. 6559, Seq. ID No. 6563, Seq. ID No. 6573, Seq. ID No. 6575, Seq. ID No. 6577, Seq. ID No. 6579, Seq. ID No. 6583, Seq. ID No. 6585, Seq. ID No. 6587, Seq. ID No. 6591, Seq. ID No. 6597, Seq. ID No. 6601, Seq. ID No. 6603, Seq. ID No. 6605, Seq. ID No. 6609, Seq. ID No. 6611, Seq. ID No. 6613, Seq. ID No. 6615, Seq. ID No. 6617, Seq. ID No. 6619, Seq. ID No. 6621, Seq. ID No. 6623, Seq. ID No. 6627, Seq. ID No. 6629, Seq. ID No. 6631, Seq. ID No. 6633, Seq. ID No. 6637, Seq. ID No. 6639, Seq. ID No. 6643, Seq. ID No. 6645, and Seq. ID No. 6649.

In another preferred embodiment, the invention comprises an isolated polynucleotide of the Alloiococcus otitidis genomic sequence encoding a polypeptide, which has been by identified by the Applicants' assignee's ORF finder program that searches for a transmembrane domain between two Stop codons and a Start codon immediately upstream of this transmembrane region, and the polynucleotide is selected from Seq. ID No. 7, Seq. ID No. 9, Seq. ID No. 33, Seq. ID No. 47, Seq. ID No. 67, Seq. ID No. 85, Seq. ID No. 87, Seq. ID No. 123, Seq. ID No. 133, Seq. ID No. 141, Seq. ID No. 159, Seq. ID No. 163, Seq. ID No. 191, Seq. ID No. 209, Seq. ID No. 211, Seq. ID No. 215, Seq. ID No. 217, Seq. ID No. 225, Seq. ID No. 235, Seq. ID No. 237, Seq. ID No. 249, Seq. ID No. 251, Seq. ID No. 255, Seq. ID No. 271, Seq. ID No. 277, Seq. ID No. 285, Seq. ID No. 287, Seq. ID No. 289, Seq. ID No. 327, Seq. ID No. 329, Seq. ID No. 373, Seq. ID No. 375, Seq. ID No. 419, Seq. ID No. 487, Seq. ID No. 497, Seq. ID No. 499, Seq. ID No. 503, Seq. ID No. 505, Seq. ID No. 509, Seq. ID No. 511, Seq. ID No. 515, Seq. ID No. 525, Seq. ID No. 527, Seq. ID No. 545, Seq. ID No. 567, Seq. ID No. 569, Seq. ID No. 575, Seq. ID No. 577, Seq. ID No. 579, Seq. ID No. 593, Seq. ID No. 617, Seq. ID No. 637, Seq. ID No. 639, Seq. ID No. 641, Seq. ID No. 645, Seq. ID No. 653, Seq. ID No. 655, Seq. ID No. 659, Seq. ID No. 669, Seq. ID No. 675, Seq. ID No. 677, Seq. ID No. 679, Seq. ID No. 715, Seq. ID No. 717, Seq. ID No. 719, Seq. ID No. 721, Seq. ID No. 723, Seq. ID No. 747, Seq. ID No. 751, Seq. ID No. 755, Seq. ID No. 757, Seq. ID No. 759, Seq. ID No. 761, Seq. ID No. 763, Seq. ID No. 769, Seq. ID No. 777, Seq. ID No. 779, Seq. ID No. 807, Seq. ID No. 809, Seq. ID No. 819, Seq. ID No. 825, Seq. ID No. 863, Seq. ID No. 893, Seq. ID No. 901, Seq. ID No. 935, Seq. ID No. 943, Seq. ID No. 955, Seq. ID No. 967, Seq. ID No. 979, Seq. ID No. 1005, Seq. ID No. 1009, Seq. ID No. 1011, Seq. ID No. 1013, Seq. ID No. 1015, Seq. ID No. 1019, Seq. ID No. 1029, Seq. ID No. 1031, Seq. ID No. 1033, Seq. ID No. 1037, Seq. ID No. 1039, Seq. ID No. 1045, Seq. ID No. 1055, Seq. ID No. 1075, Seq. ID No. 1105, Seq. ID No. 1131, Seq. ID No. 1135, Seq. ID No. 1137, Seq. ID No. 1165, Seq. ID No. 1167, Seq. ID No. 1169, Seq. ID No. 1183, Seq. ID No. 1193, Seq. ID No. 1197, Seq. ID No. 1213, Seq. ID No. 1223, Seq. ID No. 1227, Seq. ID No. 1229, Seq. ID No. 1237, Seq. ID No. 1243, Seq. ID No. 1265, Seq. ID No. 1267, Seq. ID No. 1269, Seq. ID No. 1271, Seq. ID No. 1283, Seq. ID No. 1287, Seq. ID No. 1291, Seq. ID No. 1297, Seq. ID No. 1305, Seq. ID No. 1315, Seq. ID No. 1325, Seq. ID No. 1327, Seq. ID No. 1329, Seq. ID No. 1331, Seq. ID No. 1341, Seq. ID No. 1353, Seq. ID No. 1367, Seq. ID No. 1401, Seq. ID No. 1429, Seq. ID No. 1435, Seq. ID No. 1445, Seq. ID No. 1481, Seq. ID No. 1513, Seq. ID No. 1515, Seq. ID No. 1517, Seq. ID No. 1529, Seq. ID No. 1533, Seq. ID No. 1535, Seq. ID No. 1545, Seq. ID No. 1547, Seq. ID No. 1551, Seq. ID No. 1559, Seq. ID No. 1563, Seq. ID No. 1571, Seq. ID No. 1579, Seq. ID No. 1583, Seq. ID No. 1585, Seq. ID No. 1621, Seq. ID No. 1633, Seq. ID No. 1643, Seq. ID No. 1645, Seq. ID No. 1647, Seq. ID No. 1649, Seq. ID No. 1653, Seq. ID No. 1671, Seq. ID No. 1673, Seq. ID No. 1677, Seq. ID No. 1681, Seq. ID No. 1707, Seq. ID No. 1731, Seq. ID No. 1733, Seq. ID No. 1737, Seq. ID No. 1753, Seq. ID No. 1757, Seq. ID No. 1765, Seq. ID No. 1767, Seq. ID No. 1787, Seq. ID No. 1791, Seq. ID No. 1797, Seq. ID No. 1805, Seq. ID No. 1819, Seq. ID No. 1821, Seq. ID No. 1823, Seq. ID No. 1839, Seq. ID No. 1869, Seq. ID No. 1875, Seq. ID No. 1891, Seq. ID No. 1893, Seq. ID No. 1895, Seq. ID No. 1923, Seq. ID No. 1927, Seq. ID No. 1969, Seq. ID No. 1981, Seq. ID No. 1991, Seq. ID No. 1993, Seq. ID No. 2013, Seq. ID No. 2017, Seq. ID No. 2027, Seq. ID No. 2033, Seq. ID No. 2041, Seq. ID No. 2049, Seq. ID No. 2053, Seq. ID No. 2087, Seq. ID No. 2089, Seq. ID No. 2105, Seq. ID No. 2115, Seq. ID No. 2121, Seq. ID No. 2127, Seq. ID No. 2151, Seq. ID No. 2159, Seq. ID No. 2171, Seq. ID No. 2173, Seq. ID No. 2177, Seq. ID No. 2187, Seq. ID No. 2237, Seq. ID No. 2239, Seq. ID No. 2245, Seq. ID No. 2249, Seq. ID No. 2271, Seq. ID No. 2283, Seq. ID No. 2289, Seq. ID No. 2291, Seq. ID No. 2293, Seq. ID No. 2295, Seq. ID No. 2303, Seq. ID No. 2305, Seq. ID No. 2307, Seq. ID No. 2317, Seq. ID No. 2319, Seq. ID No. 2321, Seq. ID No. 2323, Seq. ID No. 2325, Seq. ID No. 2327, Seq. ID No. 2333, Seq. ID No. 2343, Seq. ID No. 2347, Seq. ID No. 2349, Seq. ID No. 2351, Seq. ID No. 2353, Seq. ID No. 2355, Seq. ID No. 2357, Seq. ID No. 2365, Seq. ID No. 2389, Seq. ID No. 2391, Seq. ID No. 2407, Seq. ID No. 2419, Seq. ID No. 2421, Seq. ID No. 2427, Seq. ID No. 2429, Seq. ID No. 2433, Seq. ID No. 2449, Seq. ID No. 2459, Seq. ID No. 2489, Seq. ID No. 2497, Seq. ID No. 2503, Seq. ID No. 2507, Seq. ID No. 2515, Seq. ID No. 2523, Seq. ID No. 2525, Seq. ID No. 2531, Seq. ID No. 2535, Seq. ID No. 2537, Seq. ID No. 2541, Seq. ID No. 2543, Seq. ID No. 2545, Seq. ID No. 2555, Seq. ID No. 2557, Seq. ID No. 2569, Seq. ID No. 2571, Seq. ID No. 2583, Seq. ID No. 2591, Seq. ID No. 2597, Seq. ID No. 2599, Seq. ID No. 2601, Seq. ID No. 2607, Seq. ID No. 2611, Seq. ID No. 2621, Seq. ID No. 2629, Seq. ID No. 2651, Seq. ID No. 2679, Seq. ID No. 2693, Seq. ID No. 2701, Seq. ID No. 2703, Seq. ID No. 2705, Seq. ID No. 2707, Seq. ID No. 2731, Seq. ID No. 2733, Seq. ID No. 2783, Seq. ID No. 2785, Seq. ID No. 2813, Seq. ID No. 2815, Seq. ID No. 2823, Seq. ID No. 2835, Seq. ID No. 2837, Seq. ID No. 2841, Seq. ID No. 2853, Seq. ID No. 2873, Seq. ID No. 2875, Seq. ID No. 2881, Seq. ID No. 2905, Seq. ID No. 2935, Seq. ID No. 2937, Seq. ID No. 2939, Seq. ID No. 2941, Seq. ID No. 2947, Seq. ID No. 2949, Seq. ID No. 2969, Seq. ID No. 2973, Seq. ID No. 2977, Seq. ID No. 2981, Seq. ID No. 2987, Seq. ID No. 2991, Seq. ID No. 2995, Seq. ID No. 2997, Seq. ID No. 3005, Seq. ID No. 3007, Seq. ID No. 3013, Seq. ID No. 3023, Seq. ID No. 3025, Seq. ID No. 3027, Seq. ID No. 3029, Seq. ID No. 3031, Seq. ID No. 3043, Seq. ID No. 3055, Seq. ID No. 3063, Seq. ID No. 3071, Seq. ID No. 3073, Seq. ID No. 3075, Seq. ID No. 3077, Seq. ID No. 3123, Seq. ID No. 3145, Seq. ID No. 3155, Seq. ID No. 3157, Seq. ID No. 3163, Seq. ID No. 3183, Seq. ID No. 3193, Seq. ID No. 3201, Seq. ID No. 3213, Seq. ID No. 3215, Seq. ID No. 3217, Seq. ID No. 3219, Seq. ID No. 3241, Seq. ID No. 3243, Seq. ID No. 3245, Seq. ID No. 3249, Seq. ID No. 3257, Seq. ID No. 3261, Seq. ID No. 3269, Seq. ID No. 3275, Seq. ID No. 3297, Seq. ID No. 3317, Seq. ID No. 3323, Seq. ID No. 3337, Seq. ID No. 3339, Seq. ID No. 3349, Seq. ID No. 3351, Seq. ID No. 3353, Seq. ID No. 3357, Seq. ID No. 3359, Seq. ID No. 3377, Seq. ID No. 3389, Seq. ID No. 3391, Seq. ID No. 3395, Seq. ID No. 3405, Seq. ID No. 3421, Seq. ID No. 3425, Seq. ID No. 3449, Seq. ID No. 3451, Seq. ID No. 3453, Seq. ID No. 3455, Seq. ID No. 3457, Seq. ID No. 3463, Seq. ID No. 3481, Seq. ID No. 3491, Seq. ID No. 3493, Seq. ID No. 3503, Seq. ID No. 3505, Seq. ID No. 3527, Seq. ID No. 3593, Seq. ID No. 3595, Seq. ID No. 3621, Seq. ID No. 3625, Seq. ID No. 3635, Seq. ID No. 3679, Seq. ID No. 3723, Seq. ID No. 3727, Seq. ID No. 3745, Seq. ID No. 3753, Seq. ID No. 3755, Seq. ID No. 3757, Seq. ID No. 3761, Seq. ID No. 3763, Seq. ID No. 3765, Seq. ID No. 3783, Seq. ID No. 3793, Seq. ID No. 3799, Seq. ID No. 3813, Seq. ID No. 3837, Seq. ID No. 3839, Seq. ID No. 3849, Seq. ID No. 3851, Seq. ID No. 3853, Seq. ID No. 3859, Seq. ID No. 3861, Seq. ID No. 3863, Seq. ID No. 3865, Seq. ID No. 3879, Seq. ID No. 3889, Seq. ID No. 3891, Seq. ID No. 3903, Seq. ID No. 3925, Seq. ID No. 3963, Seq. ID No. 3973, Seq. ID No. 3975, Seq. ID No. 4005, Seq. ID No. 4025, Seq. ID No. 4027, Seq. ID No. 4039, Seq. ID No. 4041, Seq. ID No. 4043, Seq. ID No. 4045, Seq. ID No. 4047, Seq. ID No. 4061, Seq. ID No. 4071, Seq. ID No. 4073, Seq. ID No. 4079, Seq. ID No. 4081, Seq. ID No. 4083, Seq. ID No. 4101, Seq. ID No. 4103, Seq. ID No. 4111, Seq. ID No. 4133, Seq. ID No. 4137, Seq. ID No. 4139, Seq. ID No. 4145, Seq. ID No. 4151, Seq. ID No. 4221, Seq. ID No. 4223, Seq. ID No. 4225, Seq. ID No. 4227, Seq. ID No. 4231, Seq. ID No. 4241, Seq. ID No. 4247, Seq. ID No. 4253, Seq. ID No. 4257, Seq. ID No. 4261, Seq. ID No. 4307, Seq. ID No. 4311, Seq. ID No. 4313, Seq. ID No. 4343, Seq. ID No. 4379, Seq. ID No. 4385, Seq. ID No. 4389, Seq. ID No. 4439, Seq. ID No. 4469, Seq. ID No. 4473, Seq. ID No. 4481, Seq. ID No. 4483, Seq. ID No. 4485, Seq. ID No. 4497, Seq. ID No. 4515, Seq. ID No. 4533, Seq. ID No. 4587, Seq. ID No. 4639, Seq. ID No. 4643, Seq. ID No. 4681, Seq. ID No. 4705, Seq. ID No. 4707, Seq. ID No. 4709, Seq. ID No. 4711, Seq. ID No. 4715, Seq. ID No. 4717, Seq. ID No. 4737, Seq. ID No. 4759, Seq. ID No. 4813, Seq. ID No. 4827, Seq. ID No. 4869, Seq. ID No. 4871, Seq. ID No. 4873, Seq. ID No. 4875, Seq. ID No. 4919, Seq. ID No. 4931, Seq. ID No. 4949, Seq. ID No. 4951, Seq. ID No. 4987, Seq. ID No. 5031, Seq. ID No. 5061, Seq. ID No. 5085, Seq. ID No. 5103, Seq. ID No. 5123, Seq. ID No. 5129, Seq. ID No. 5131, Seq. ID No. 5135, Seq. ID No. 5137, Seq. ID No. 5141, Seq. ID No. 5165, Seq. ID No. 5175, Seq. ID No. 5199, Seq. ID No. 5205, Seq. ID No. 5207, Seq. ID No. 5213, Seq. ID No. 5219, Seq. ID No. 5223, Seq. ID No. 5267, Seq. ID No. 5281, Seq. ID No. 5385, Seq. ID No. 5387, Seq. ID No. 5413, Seq. ID No. 5415, Seq. ID No. 5433, Seq. ID No. 5453, Seq. ID No. 5459, Seq. ID No. 5461, Seq. ID No. 5463, Seq. ID No. 5465, Seq. ID No. 5491, Seq. ID No. 5497, Seq. ID No. 5509, Seq. ID No. 5513, Seq. ID No. 5525, Seq. ID No. 5531, Seq. ID No. 5569, Seq. ID No. 5587, Seq. ID No. 5595, Seq. ID No. 5597, Seq. ID No. 5609, Seq. ID No. 5611, Seq. ID No. 5621, Seq. ID No. 5623, Seq. ID No. 5633, Seq. ID No. 5637, Seq. ID No. 5643, Seq. ID No. 5649, Seq. ID No. 5659, Seq. ID No. 5683, Seq. ID No. 5685, Seq. ID No. 5699, Seq. ID No. 5705, Seq. ID No. 5709, Seq. ID No. 5729, Seq. ID No. 5733, Seq. ID No. 5763, Seq. ID No. 5765, Seq. ID No. 5767, Seq. ID No. 5771, Seq. ID No. 5783, Seq. ID No. 5791, Seq. ID No. 5797, Seq. ID No. 5885, Seq. ID No. 5889, Seq. ID No. 5893, Seq. ID No. 5895, Seq. ID No. 5899, Seq. ID No. 5901, Seq. ID No. 5905, Seq. ID No. 5909, Seq. ID No. 5921, Seq. ID No. 5923, Seq. ID No. 5927, Seq. ID No. 5939, Seq. ID No. 6027, Seq. ID No. 6043, Seq. ID No. 6047, Seq. ID No. 6059, Seq. ID No. 6067, Seq. ID No. 6089, Seq. ID No. 6091, Seq. ID No. 6107, Seq. ID No. 6111, Seq. ID No. 6117, Seq. ID No. 6161, Seq. ID No. 6163, Seq. ID No. 6165, Seq. ID No. 6169, Seq. ID No. 6183, Seq. ID No. 6185, Seq. ID No. 6189, Seq. ID No. 6191, Seq. ID No. 6197, Seq. ID No. 6203, Seq. ID No. 6205, Seq. ID No. 6209, Seq. ID No. 6221, Seq. ID No. 6223, Seq. ID No. 6225, Seq. ID No. 6227, Seq. ID No. 6229, Seq. ID No. 6235, Seq. ID No. 6237, Seq. ID No. 6243, Seq. ID No. 6245, Seq. ID No. 6249, Seq. ID No. 6253, Seq. ID No. 6263, Seq. ID No. 6265, Seq. ID No. 6273, Seq. ID No. 6275, Seq. ID No. 6285, Seq. ID No. 6289, Seq. ID No. 6301, Seq. ID No. 6303, Seq. ID No. 6363, Seq. ID No. 6377, Seq. ID No. 6381, Seq. ID No. 6383, Seq. ID No. 6415, Seq. ID No. 6427, Seq. ID No. 6431, Seq. ID No. 6473, Seq. ID No. 6497, Seq. ID No. 6571, Seq. ID No. 6581, Seq. ID No. 6593, Seq. ID No. 6599, Seq. ID No. 6631, and Seq. ID No. 6639.

In one preferred embodiment,the invention comprises an isolated polynucleotide of an Alloiococcus otitidis genomic sequence, wherein the polynucleotide comprises a nucleotide sequence having at least about 70% identity to a nucleotide sequence contained within SEQ ID NO: 6651, a complement thereof, a degenerate variant thereof, and a fragment thereof.

In other preferred embodiments, the invention comprises an isolated polypeptide encoded by a polynucleotide and having at least about 70% identity to a nucleotide sequence chosen from one of the odd numbered sequence listings set out in SEQ ID NO: 1 through SEQ ID NO: 6649.

In certain aspects, the invention relates to Alloiococcus otitidis polypeptides. More particularly, the invention relates to Alloiococcus otitidis polypeptides, more preferably antigenic polypeptides, encoded by Alloiococcus otitidis polynucleotide open reading frames. Thus, in certain embodiments, an isolated polypeptide is encoded by a polynucleotide comprising a nucleotide sequence having at least about 70% identity to a nucleotide sequence chosen from one of odd numbered sequences set out in SEQ ID NO: 1 through SEQ ID NO: 6649, a complement thereof, a degenerate variant thereof, or a fragment thereof. In a preferred embodiment, the isolated polypeptide encoded by one of the above polynucleotides comprises an amino acid sequence having at least about 70% identity to an amino acid sequence chosen from one of the even numbered sequences set out in SEQ ID NO: 2 through SEQ ID NO: 6650, a biological equivalent thereof, or a fragment thereof. In other embodiments, the polypeptide is a fusion polypeptide. In a preferred embodiment, the polypeptide immunoreacts with seropositive serum of an individual previously infected with Alloiococcus otitidis, a biological equivalent thereof, or a fragment thereof.

In other preferred embodiments, the isolated polypeptide encoded is selected from (a) an Alloiococcus otitidis polypeptide predicted by SignalP algorithm analysis as having met all four criteria set out in the SignalP algorithm for a polypeptide having a signal peptide and a subset of these are predicted by HMM SignalP algorithm analysis as having a signal peptide; (b) an Alloiococcus otitidis polypeptide predicted by SignalP algorithm analysis as having met three of the four criteria set out in the SignalP algorithm for a polypeptide having a signal peptide and a subset of these predicted by HMM SignalP algorithm analysis as having a signal peptide; (c) an Alloiococcus otitidis polypeptide predicted by HMM SignalP algorithm analysis as having a signal peptide; (d) an Alloiococcus otitidis polypeptide predicted by HMM SignalP algorithm analysis as being a non-secretory protein; (e) an Alloiococcus otitidis polypeptide identified by Pfam analysis; (f) an Alloiococcus otitidis polypeptide identified by BlastP analysis; (g) an Alloiococcus otitidis polypeptide identified using proteomics methodology as sharing homology with surface exposed proteins of Streptococcus pneumoniae; (h) an Alloiococcus otitidis polypeptide having a LPXTG motif, wherein the polypeptide is covalently attached to the peptidoglycan layer; (i) an Alloiococcus otitidis lipoprotein; (j) an Alloiococcus otitidis polypeptide non-covalently associated with the peptidoglycan layer; (k) an Alloiococcus otitidis polypeptide having an RGDX motif wherein X is not a proline residue; (l) an Alloiococcus otitidis polypeptide predicted by BlastP as being involved in capsule biosynthesis and transport; (m) an Alloiococcus otitidis polypeptide identified by BlastP as being localized within the capsule loci of the Alloiococcus otitidis genome; (n) an Alloiococcus otitidis polypeptide predicted by BlastP as being associated with sporulation; (o) an Alloiococcus otitidis polypeptide encoded by unique ORFs identified by BlastP analysis as having a BlastP ‘E Value’ of >e⁻¹⁰; (p) an Alloiococcus otitidis polypeptide identified by Glimmer™ ORF finder program; (q) an Alloiococcus otitidis polypeptide identified by GeneMark™ ORF finder program; (r) an Alloiococcus otitidis polypeptide identified by Applicants' assignee's ORF finder program that searches for an ATG, GTG or TTG Start codon between a Stop-Stop region; and (s) an Alloiococcus otitidis polypeptide identified by Applicants' assignee's ORF finder program that searches for a transmembrane domain between two Stop codons and a Start codon immediately upstream of this transmembrane region.

In a preferred embodiment, the polypeptide is selected from the Alloiococcus otitidis polypeptides predicted by SignalP algorithm analysis as having met all four criteria set out in the SignalP algorithm for a polypeptide having a signal peptide and is selected from one of Seq. ID No. 90, Seq. ID No. 128, Seq. ID No. 132, Seq. ID No. 134, Seq. ID No. 162, Seq. ID No. 164, Seq. ID No. 214, Seq. ID No. 216, Seq. ID No. 226, Seq. ID No. 250, Seq. ID No. 252, Seq. ID No. 288, Seq. ID No. 290, Seq. ID No. 370, Seq. ID No. 372, Seq. ID No. 376, Seq. ID No. 378, Seq. ID No. 498, Seq. ID No. 504, Seq. ID No. 506, Seq. ID No. 528, Seq. ID No. 550, Seq. ID No. 576, Seq. ID No. 618, Seq. ID No. 658, Seq. ID No. 660, Seq. ID No. 662, Seq. ID No. 676, Seq. ID No. 716, Seq. ID No. 718, Seq. ID No. 746, Seq. ID No. 748, Seq. ID No. 756, Seq. ID No. 758, Seq. ID No. 760, Seq. ID No. 762, Seq. ID No. 774, Seq. ID No. 808, Seq. ID No. 968, Seq. ID No. 974, Seq. ID No. 976, Seq. ID No. 1014, Seq. ID No. 1026, Seq. ID No. 1028, Seq. ID No. 1040, Seq. ID No. 1076, Seq. ID No. 1090, Seq. ID No. 1196, Seq. ID No. 1198, Seq. ID No. 1208, Seq. ID No. 1240, Seq. ID No. 1244, Seq. ID No. 1246, Seq. ID No. 1270, Seq. ID No. 1316, Seq. ID No. 1318, Seq. ID No. 1332, Seq. ID No. 1366, Seq. ID No. 1368, Seq. ID No. 1370, Seq. ID No. 1446, Seq. ID No. 1448, Seq. ID No. 1514, Seq. ID No. 1518, Seq. ID No. 1546, Seq. ID No. 1550, Seq. ID No. 1562, Seq. ID No. 1570, Seq. ID No. 1572, Seq. ID No. 1586, Seq. ID No. 1644, Seq. ID No. 1654, Seq. ID No. 1662, Seq. ID No. 1664, Seq. ID No. 1708, Seq. ID No. 1734, Seq. ID No. 1738, Seq. ID No. 1756, Seq. ID No. 1766, Seq. ID No. 1768, Seq. ID No. 1776, Seq. ID No. 1792, Seq. ID No. 1806, Seq. ID No. 1876, Seq. ID No. 1970, Seq. ID No. 1982, Seq. ID No. 2054, Seq. ID No. 2056, Seq. ID No. 2088, Seq. ID No. 2090, Seq. ID No. 2092, Seq. ID No. 2106, Seq. ID No. 2116, Seq. ID No. 2150, Seq. ID No. 2152, Seq. ID No. 2160, Seq. ID No. 2178, Seq. ID No. 2278, Seq. ID No. 2294, Seq. ID No. 2322, Seq. ID No. 2348, Seq. ID No. 2352, Seq. ID No. 2354, Seq. ID No. 2366, Seq. ID No. 2396, Seq. ID No. 2422, Seq. ID No. 2426, Seq. ID No. 2428, Seq. ID No. 2430, Seq. ID No. 2450, Seq. ID No. 2460, Seq. ID No. 2526, Seq. ID No. 2532, Seq. ID No. 2608, Seq. ID No. 2652, Seq. ID No. 2680, Seq. ID No. 2694, Seq. ID No. 2700, Seq. ID No. 2704, Seq. ID No. 2754, Seq. ID No. 2786, Seq. ID No. 2814, Seq. ID No. 2830, Seq. ID No. 2836, Seq. ID No. 2842, Seq. ID No. 2880, Seq. ID No. 2882, Seq. ID No. 2936, Seq. ID No. 2938, Seq. ID No. 2950, Seq. ID No. 2966, Seq. ID No. 2968, Seq. ID No. 2974, Seq. ID No. 3008, Seq. ID No. 3010, Seq. ID No. 3012, Seq. ID No. 3030, Seq. ID No. 3032, Seq. ID No. 3110, Seq. ID No. 3112, Seq. ID No. 3220, Seq. ID No. 3224, Seq. ID No. 3274, Seq. ID No. 3298, Seq. ID No. 3332, Seq. ID No. 3336, Seq. ID No. 3342, Seq. ID No. 3350, Seq. ID No. 3354, Seq. ID No. 3356, Seq. ID No. 3378, Seq. ID No. 3392, Seq. ID No. 3426, Seq. ID No. 3450, Seq. ID No. 3494, Seq. ID No. 3574, Seq. ID No. 3612, Seq. ID No. 3620, Seq. ID No. 3690, Seq. ID No. 3754, Seq. ID No. 3756, Seq. ID No. 3766, Seq. ID No. 3782, Seq. ID No. 3784, Seq. ID No. 3852, Seq. ID No. 3904, Seq. ID No. 4006, Seq. ID No. 4008, Seq. ID No. 4028, Seq. ID No. 4074, Seq. ID No. 4138, Seq. ID No. 4142, Seq. ID No. 4144, Seq. ID No. 4146, Seq. ID No. 4226, Seq. ID No. 4344, Seq. ID No. 4386, Seq. ID No. 4400, Seq. ID No. 4470, Seq. ID No. 4484, Seq. ID No. 4494, Seq. ID No. 4496, Seq. ID No. 4534, Seq. ID No. 4700, Seq. ID No. 4710, Seq. ID No. 4712, Seq. ID No. 4736, Seq. ID No. 4828, Seq. ID No. 4872, Seq. ID No. 4874, Seq. ID No. 4880, Seq. ID No. 4922, Seq. ID No. 4982, Seq. ID No. 5116, Seq. ID No. 5268, Seq. ID No. 5342, Seq. ID No. 5388, Seq. ID No. 5466, Seq. ID No. 5468, Seq. ID No. 5480, Seq. ID No. 5498, Seq. ID No. 5514, Seq. ID No. 5544, Seq. ID No. 5546, Seq. ID No. 5568, Seq. ID No. 5588, Seq. ID No. 5590, Seq. ID No. 5592, Seq. ID No. 5612, Seq. ID No. 5622, Seq. ID No. 5642, Seq. ID No. 5682, Seq. ID No. 5720, Seq. ID No. 5772, Seq. ID No. 5784, Seq. ID No. 5896, Seq. ID No. 5900, Seq. ID No. 5902, Seq. ID No. 5928, Seq. ID No. 5930, Seq. ID No. 5940, Seq. ID No. 5988, Seq. ID No. 6014, Seq. ID No. 6088, Seq. ID No. 6090, Seq. ID No. 6092, Seq. ID No. 6094, Seq. ID No. 6096, Seq. ID No. 6104, Seq. ID No. 6170, Seq. ID No. 6186, Seq. ID No. 6188, Seq. ID No. 6196, Seq. ID No. 6198, Seq. ID No. 6204, Seq. ID No. 6206, Seq. ID No. 6222, Seq. ID No. 6224, Seq. ID No. 6230, Seq. ID No. 6292, Seq. ID No. 6416, Seq. ID No. 6418, Seq. ID No. 6474, Seq. ID No. 6508, Seq. ID No. 6544, Seq. ID No. 6596, Seq. ID No. 6598, Seq. ID No. 6600, Seq. ID No. 6602, and Seq. ID No. 6604.

In another preferred embodiment, the polypeptide is selected from Alloiococcus otitidis polypeptides predicted by SignalP algorithm analysis as having met three of the four criteria set out in the SignalP algorithm for a polypeptide having a signal peptide and predicted by HMM SignalP algorithm analysis as having a signal peptide and is selected from one of Seq. ID No. 8, Seq. ID No. 12, Seq. ID No. 24, Seq. ID No. 46, Seq. ID No. 48, Seq. ID No. 54, Seq. ID No. 60, Seq. ID No. 66, Seq. ID No. 68, Seq. ID No. 88, Seq. ID No. 92, Seq. ID No. 140, Seq. ID No. 152, Seq. ID No. 160, Seq. ID No. 166, Seq. ID No. 170, Seq. ID No. 186, Seq. ID No. 212, Seq. ID No. 218, Seq. ID No. 236, Seq. ID No. 238, Seq. ID No. 240, Seq. ID No. 272, Seq. ID No. 286, Seq. ID No. 292, Seq. ID No. 328, Seq. ID No. 350, Seq. ID No. 386, Seq. ID No. 388, Seq. ID No. 408, Seq. ID No. 428, Seq. ID No. 432, Seq. ID No. 456, Seq. ID No. 458, Seq. ID No. 496, Seq. ID No. 500, Seq. ID No. 512, Seq. ID No. 514, Seq. ID No. 516, Seq. ID No. 526, Seq. ID No. 546, Seq. ID No. 548, Seq. ID No. 558, Seq. ID No. 570, Seq. ID No. 590, Seq. ID No. 592, Seq. ID No. 594, Seq. ID No. 596, Seq. ID No. 610, Seq. ID No. 638, Seq. ID No. 640, Seq. ID No. 642, Seq. ID No. 654, Seq. ID No. 670, Seq. ID No. 680, Seq. ID No. 720, Seq. ID No. 724, Seq. ID No. 740, Seq. ID No. 750, Seq. ID No. 752, Seq. ID No. 764, Seq. ID No. 766, Seq. ID No. 770, Seq. ID No. 778, Seq. ID No. 780, Seq. ID No. 782, Seq. ID No. 820, Seq. ID No. 896, Seq. ID No. 904, Seq. ID No. 906, Seq. ID No. 910, Seq. ID No. 936, Seq. ID No. 938, Seq. ID No. 952, Seq. ID No. 956, Seq. ID No. 980, Seq. ID No. 982, Seq. ID No. 984, Seq. ID No. 986, Seq. ID No. 1006, Seq. ID No. 1008, Seq. ID No. 1010, Seq. ID No. 1016, Seq. ID No. 1020, Seq. ID No. 1030, Seq. ID No. 1032, Seq. ID No. 1048, Seq. ID No. 1092, Seq. ID No. 1112, Seq. ID No. 1138, Seq. ID No. 1152, Seq. ID No. 1154, Seq. ID No. 1170, Seq. ID No. 1174, Seq. ID No. 1184, Seq. ID No. 1192, Seq. ID No. 1194, Seq. ID No. 1214, Seq. ID No. 1224, Seq. ID No. 1230, Seq. ID No. 1248, Seq. ID No. 1260, Seq. ID No. 1284, Seq. ID No. 1308, Seq. ID No. 1320, Seq. ID No. 1322, Seq. ID No. 1328, Seq. ID No. 1342, Seq. ID No. 1344, Seq. ID No. 1348, Seq. ID No. 1390, Seq. ID No. 1402, Seq. ID No. 1430, Seq. ID No. 1480, Seq. ID No. 1552, Seq. ID No. 1560, Seq. ID No. 1580, Seq. ID No. 1588, Seq. ID No. 1622, Seq. ID No. 1628, Seq. ID No. 1634, Seq. ID No. 1646, Seq. ID No. 1648, Seq. ID No. 1650, Seq. ID No. 1656, Seq. ID No. 1666, Seq. ID No. 1668, Seq. ID No. 1672, Seq. ID No. 1678, Seq. ID No. 1680, Seq. ID No. 1682, Seq. ID No. 1696, Seq. ID No. 1704, Seq. ID No. 1706, Seq. ID No. 1732, Seq. ID No. 1754, Seq. ID No. 1760, Seq. ID No. 1764, Seq. ID No. 1788, Seq. ID No. 1798, Seq. ID No. 1822, Seq. ID No. 1824, Seq. ID No. 1834, Seq. ID No. 1840, Seq. ID No. 1842, Seq. ID No. 1844, Seq. ID No. 1894, Seq. ID No. 1918, Seq. ID No. 1920, Seq. ID No. 1972, Seq. ID No. 1992, Seq. ID No. 2014, Seq. ID No. 2016, Seq. ID No. 2018, Seq. ID No. 2020, Seq. ID No. 2034, Seq. ID No. 2036, Seq. ID No. 2050, Seq. ID No. 2082, Seq. ID No. 2084, Seq. ID No. 2086, Seq. ID No. 2112, Seq. ID No. 2114, Seq. ID No. 2124, Seq. ID No. 2126, Seq. ID No. 2128, Seq. ID No. 2132, Seq. ID No. 2134, Seq. ID No. 2154, Seq. ID No. 2162, Seq. ID No. 2172, Seq. ID No. 2176, Seq. ID No. 2180, Seq. ID No. 2188, Seq. ID No. 2202, Seq. ID No. 2204, Seq. ID No. 2222, Seq. ID No. 2238, Seq. ID No. 2250, Seq. ID No. 2252, Seq. ID No. 2256, Seq. ID No. 2262, Seq. ID No. 2264, Seq. ID No. 2272, Seq. ID No. 2280, Seq. ID No. 2284, Seq. ID No. 2286, Seq. ID No. 2290, Seq. ID No. 2296, Seq. ID No. 2306, Seq. ID No. 2308, Seq. ID No. 2318, Seq. ID No. 2320, Seq. ID No. 2324, Seq. ID No. 2326, Seq. ID No. 2344, Seq. ID No. 2350, Seq. ID No. 2386, Seq. ID No. 2394, Seq. ID No. 2424, Seq. ID No. 2454, Seq. ID No. 2492, Seq. ID No. 2498, Seq. ID No. 2500, Seq. ID No. 2508, Seq. ID No. 2516, Seq. ID No. 2518, Seq. ID No. 2522, Seq. ID No. 2524, Seq. ID No. 2528, Seq. ID No. 2534, Seq. ID No. 2536, Seq. ID No. 2542, Seq. ID No. 2544, Seq. ID No. 2548, Seq. ID No. 2550, Seq. ID No. 2558, Seq. ID No. 2574, Seq. ID No. 2584, Seq. ID No. 2602, Seq. ID No. 2604, Seq. ID No. 2622, Seq. ID No. 2654, Seq. ID No. 2682, Seq. ID No. 2692, Seq. ID No. 2702, Seq. ID No. 2734, Seq. ID No. 2740, Seq. ID No. 2802, Seq. ID No. 2808, Seq. ID No. 2816, Seq. ID No. 2820, Seq. ID No. 2822, Seq. ID No. 2824, Seq. ID No. 2834, Seq. ID No. 2838, Seq. ID No. 2840, Seq. ID No. 2846, Seq. ID No. 2854, Seq. ID No. 2862, Seq. ID No. 2866, Seq. ID No. 2874, Seq. ID No. 2876, Seq. ID No. 2878, Seq. ID No. 2884, Seq. ID No. 2896, Seq. ID No. 2906, Seq. ID No. 2940, Seq. ID No. 2942, Seq. ID No. 2948, Seq. ID No. 2982, Seq. ID No. 2984, Seq. ID No. 2988, Seq. ID No. 2992, Seq. ID No. 2996, Seq. ID No. 3002, Seq. ID No. 3006, Seq. ID No. 3022, Seq. ID No. 3026, Seq. ID No. 3044, Seq. ID No. 3046, Seq. ID No. 3074, Seq. ID No. 3076, Seq. ID No. 3156, Seq. ID No. 3164, Seq. ID No. 3166, Seq. ID No. 3168, Seq. ID No. 3184, Seq. ID No. 3214, Seq. ID No. 3216, Seq. ID No. 3236, Seq. ID No. 3246, Seq. ID No. 3262, Seq. ID No. 3264, Seq. ID No. 3266, Seq. ID No. 3270, Seq. ID No. 3272, Seq. ID No. 3276, Seq. ID No. 3278, Seq. ID No. 3318, Seq. ID No. 3326, Seq. ID No. 3338, Seq. ID No. 3352, Seq. ID No. 3390, Seq. ID No. 3406, Seq. ID No. 3420, Seq. ID No. 3422, Seq. ID No. 3424, Seq. ID No. 3452, Seq. ID No. 3454, Seq. ID No. 3456, Seq. ID No. 3492, Seq. ID No. 3496, Seq. ID No. 3504, Seq. ID No. 3506, Seq. ID No. 3518, Seq. ID No. 3520, Seq. ID No. 3546, Seq. ID No. 3548, Seq. ID No. 3572, Seq. ID No. 3594, Seq. ID No. 3618, Seq. ID No. 3622, Seq. ID No. 3630, Seq. ID No. 3664, Seq. ID No. 3702, Seq. ID No. 3704, Seq. ID No. 3724, Seq. ID No. 3738, Seq. ID No. 3742, Seq. ID No. 3746, Seq. ID No. 3748, Seq. ID No. 3760, Seq. ID No. 3764, Seq. ID No. 3768, Seq. ID No. 3770, Seq. ID No. 3772, Seq. ID No. 3786, Seq. ID No. 3794, Seq. ID No. 3814, Seq. ID No. 3838, Seq. ID No. 3840, Seq. ID No. 3862, Seq. ID No. 3866, Seq. ID No. 3890, Seq. ID No. 3892, Seq. ID No. 3896, Seq. ID No. 3916, Seq. ID No. 3924, Seq. ID No. 3926, Seq. ID No. 3930, Seq. ID No. 3966, Seq. ID No. 3976, Seq. ID No. 3980, Seq. ID No. 3996, Seq. ID No. 3998, Seq. ID No. 4010, Seq. ID No. 4040, Seq. ID No. 4042, Seq. ID No. 4062, Seq. ID No. 4080, Seq. ID No. 4082, Seq. ID No. 4112, Seq. ID No. 4114, Seq. ID No. 4136, Seq. ID No. 4140, Seq. ID No. 4156, Seq. ID No. 4182, Seq. ID No. 4204, Seq. ID No. 4222, Seq. ID No. 4248, Seq. ID No. 4254, Seq. ID No. 4258, Seq. ID No. 4260, Seq. ID No. 4262, Seq. ID No. 4264, Seq. ID No. 4270, Seq. ID No. 4312, Seq. ID No. 4380, Seq. ID No. 4390, Seq. ID No. 4392, Seq. ID No. 4472, Seq. ID No. 4474, Seq. ID No. 4482, Seq. ID No. 4526, Seq. ID No. 4552, Seq. ID No. 4562, Seq. ID No. 4574, Seq. ID No. 4618, Seq. ID No. 4640, Seq. ID No. 4660, Seq. ID No. 4682, Seq. ID No. 4702, Seq. ID No. 4706, Seq. ID No. 4714, Seq. ID No. 4718, Seq. ID No. 4722, Seq. ID No. 4738, Seq. ID No. 4742, Seq. ID No. 4814, Seq. ID No. 4818, Seq. ID No. 4820, Seq. ID No. 4830, Seq. ID No. 4832, Seq. ID No. 4852, Seq. ID No. 4870, Seq. ID No. 4876, Seq. ID No. 4914, Seq. ID No. 4920, Seq. ID No. 4930, Seq. ID No. 4932, Seq. ID No. 4984, Seq. ID No. 4994, Seq. ID No. 5012, Seq. ID No. 5024, Seq. ID No. 5032, Seq. ID No. 5034, Seq. ID No. 5036, Seq. ID No. 5044, Seq. ID No. 5062, Seq. ID No. 5064, Seq. ID No. 5070, Seq. ID No. 5104, Seq. ID No. 5122, Seq. ID No. 5124, Seq. ID No. 5132, Seq. ID No. 5134, Seq. ID No. 5136, Seq. ID No. 5138, Seq. ID No. 5140, Seq. ID No. 5142, Seq. ID No. 5152, Seq. ID No. 5160, Seq. ID No. 5162, Seq. ID No. 5166, Seq. ID No. 5168, Seq. ID No. 5176, Seq. ID No. 5178, Seq. ID No. 5206, Seq. ID No. 5208, Seq. ID No. 5212, Seq. ID No. 5216, Seq. ID No. 5220, Seq. ID No. 5224, Seq. ID No. 5286, Seq. ID No. 5288, Seq. ID No. 5330, Seq. ID No. 5332, Seq. ID No. 5378, Seq. ID No. 5380, Seq. ID No. 5382, Seq. ID No. 5386, Seq. ID No. 5406, Seq. ID No. 5408, Seq. ID No. 5454, Seq. ID No. 5460, Seq. ID No. 5462, Seq. ID No. 5464, Seq. ID No. 5482, Seq. ID No. 5510, Seq. ID No. 5530, Seq. ID No. 5532, Seq. ID No. 5558, Seq. ID No. 5570, Seq. ID No. 5578, Seq. ID No. 5624, Seq. ID No. 5626, Seq. ID No. 5644, Seq. ID No. 5660, Seq. ID No. 5662, Seq. ID No. 5684, Seq. ID No. 5686, Seq. ID No. 5710, Seq. ID No. 5712, Seq. ID No. 5734, Seq. ID No. 5740, Seq. ID No. 5766, Seq. ID No. 5798, Seq. ID No. 5828, Seq. ID No. 5890, Seq. ID No. 5894, Seq. ID No. 5906, Seq. ID No. 5910, Seq. ID No. 5912, Seq. ID No. 5924, Seq. ID No. 5964, Seq. ID No. 5966, Seq. ID No. 6026, Seq. ID No. 6028, Seq. ID No. 6032, Seq. ID No. 6044, Seq. ID No. 6046, Seq. ID No. 6048, Seq. ID No. 6054, Seq. ID No. 6060, Seq. ID No. 6110, Seq. ID No. 6112, Seq. ID No. 6116, Seq. ID No. 6118, Seq. ID No. 6128, Seq. ID No. 6132, Seq. ID No. 6136, Seq. ID No. 6138, Seq. ID No. 6162, Seq. ID No. 6166, Seq. ID No. 6184, Seq. ID No. 6190, Seq. ID No. 6192, Seq. ID No. 6194, Seq. ID No. 6208, Seq. ID No. 6210, Seq. ID No. 6218, Seq. ID No. 6226, Seq. ID No. 6236, Seq. ID No. 6244, Seq. ID No. 6250, Seq. ID No. 6254, Seq. ID No. 6260, Seq. ID No. 6266, Seq. ID No. 6268, Seq. ID No. 6276, Seq. ID No. 6284, Seq. ID No. 6286, Seq. ID No. 6304, Seq. ID No. 6326, Seq. ID No. 6328, Seq. ID No. 6364, Seq. ID No. 6366, Seq. ID No. 6368, Seq. ID No. 6386, Seq. ID No. 6426, Seq. ID No. 6428, Seq. ID No. 6430, Seq. ID No. 6432, Seq. ID No. 6454, Seq. ID No. 6466, Seq. ID No. 6470, Seq. ID No. 6472, Seq. ID No. 6480, Seq. ID No. 6540, Seq. ID No. 6542, Seq. ID No. 6572, Seq. ID No. 6574, Seq. ID No. 6640, Seq. ID No. 6644, and Seq. ID No. 6646.

In yet another preferred embodiment, the polypeptide is selected from the Alloiococcus otitidis polypeptides, which are predicted by HMM SignalP algorithm analysis as having a signal peptide and is selected from one of Seq. ID No. 4, Seq. ID No. 8, Seq. ID No. 10, Seq. ID No. 20, Seq. ID No. 22, Seq. ID No. 32, Seq. ID No. 34, Seq. ID No. 46, Seq. ID No. 48, Seq. ID No. 50, Seq. ID No. 54, Seq. ID No. 66, Seq. ID No. 68, Seq. ID No. 86, Seq. ID No. 88, Seq. ID No. 106, Seq. ID No. 112, Seq. ID No. 124, Seq. ID No. 132, Seq. ID No. 134, Seq. ID No. 142, Seq. ID No. 160, Seq. ID No. 162, Seq. ID No. 164, Seq. ID No. 172, Seq. ID No. 192, Seq. ID No. 210, Seq. ID No. 212, Seq. ID No. 214, Seq. ID No. 216, Seq. ID No. 218, Seq. ID No. 226, Seq. ID No. 236, Seq. ID No. 238, Seq. ID No. 250, Seq. ID No. 252, Seq. ID No. 256, Seq. ID No. 258, Seq. ID No. 260, Seq. ID No. 272, Seq. ID No. 274, Seq. ID No. 278, Seq. ID No. 286, Seq. ID No. 288, Seq. ID No. 290, Seq. ID No. 328, Seq. ID No. 330, Seq. ID No. 358, Seq. ID No. 360, Seq. ID No. 374, Seq. ID No. 376, Seq. ID No. 394, Seq. ID No. 402, Seq. ID No. 404, Seq. ID No. 456, Seq. ID No. 458, Seq. ID No. 478, Seq. ID No. 488, Seq. ID No. 490, Seq. ID No. 492, Seq. ID No. 494, Seq. ID No. 496, Seq. ID No. 498, Seq. ID No. 500, Seq. ID No. 504, Seq. ID No. 506, Seq. ID No. 510, Seq. ID No. 512, Seq. ID No. 514, Seq. ID No. 516, Seq. ID No. 526, Seq. ID No. 528, Seq. ID No. 546, Seq. ID No. 548, Seq. ID No. 550, Seq. ID No. 558, Seq. ID No. 568, Seq. ID No. 570, Seq. ID No. 576, Seq. ID No. 578, Seq. ID No. 580, Seq. ID No. 592, Seq. ID No. 594, Seq. ID No. 600, Seq. ID No. 618, Seq. ID No. 638, Seq. ID No. 640, Seq. ID No. 642, Seq. ID No. 644, Seq. ID No. 646, Seq. ID No. 648, Seq. ID No. 654, Seq. ID No. 656, Seq. ID No. 658, Seq. ID No. 660, Seq. ID No. 662, Seq. ID No. 668, Seq. ID No. 670, Seq. ID No. 676, Seq. ID No. 678, Seq. ID No. 680, Seq. ID No. 716, Seq. ID No. 718, Seq. ID No. 720, Seq. ID No. 722, Seq. ID No. 724, Seq. ID No. 726, Seq. ID No. 746, Seq. ID No. 748, Seq. ID No. 750, Seq. ID No. 752, Seq. ID No. 756, Seq. ID No. 758, Seq. ID No. 760, Seq. ID No. 762, Seq. ID No. 764, Seq. ID No. 766, Seq. ID No. 770, Seq. ID No. 778, Seq. ID No. 780, Seq. ID No. 782, Seq. ID No. 808, Seq. ID No. 810, Seq. ID No. 820, Seq. ID No. 826, Seq. ID No. 864, Seq. ID No. 894, Seq. ID No. 902, Seq. ID No. 936, Seq. ID No. 938, Seq. ID No. 942, Seq. ID No. 944, Seq. ID No. 956, Seq. ID No. 958, Seq. ID No. 968, Seq. ID No. 980, Seq. ID No. 982, Seq. ID No. 984, Seq. ID No. 986, Seq. ID No. 1002, Seq. ID No. 1004, Seq. ID No. 1006, Seq. ID No. 1008, Seq. ID No. 1010, Seq. ID No. 1012, Seq. ID No. 1014, Seq. ID No. 1016, Seq. ID No. 1020, Seq. ID No. 1030, Seq. ID No. 1032, Seq. ID No. 1034, Seq. ID No. 1036, Seq. ID No. 1038, Seq. ID No. 1040, Seq. ID No. 1046, Seq. ID No. 1056, Seq. ID No. 1076, Seq. ID No. 1078, Seq. ID No. 1106, Seq. ID No. 1108, Seq. ID No. 1132, Seq. ID No. 1136, Seq. ID No. 1138, Seq. ID No. 1140, Seq. ID No. 1152, Seq. ID No. 1166, Seq. ID No. 1168, Seq. ID No. 1170, Seq. ID No. 1174, Seq. ID No. 1184, Seq. ID No. 1196, Seq. ID No. 1198, Seq. ID No. 1204, Seq. ID No. 1214, Seq. ID No. 1224, Seq. ID No. 1228, Seq. ID No. 1230, Seq. ID No. 1238, Seq. ID No. 1244, Seq. ID No. 1246, Seq. ID No. 1260, Seq. ID No. 1266, Seq. ID No. 1268, Seq. ID No. 1270, Seq. ID No. 1272, Seq. ID No. 1284, Seq. ID No. 1288, Seq. ID No. 1290, Seq. ID No. 1292, Seq. ID No. 1296, Seq. ID No. 1298, Seq. ID No. 1304, Seq. ID No. 1306, Seq. ID No. 1316, Seq. ID No. 1318, Seq. ID No. 1320, Seq. ID No. 1326, Seq. ID No. 1328, Seq. ID No. 1330, Seq. ID No. 1332, Seq. ID No. 1338, Seq. ID No. 1342, Seq. ID No. 1344, Seq. ID No. 1348, Seq. ID No. 1350, Seq. ID No. 1352, Seq. ID No. 1354, Seq. ID No. 1366, Seq. ID No. 1368, Seq. ID No. 1370, Seq. ID No. 1372, Seq. ID No. 1382, Seq. ID No. 1402, Seq. ID No. 1430, Seq. ID No. 1436, Seq. ID No. 1446, Seq. ID No. 1448, Seq. ID No. 1482, Seq. ID No. 1514, Seq. ID No. 1516, Seq. ID No. 1518, Seq. ID No. 1530, Seq. ID No. 1534, Seq. ID No. 1536, Seq. ID No. 1546, Seq. ID No. 1548, Seq. ID No. 1552, Seq. ID No. 1554, Seq. ID No. 1560, Seq. ID No. 1562, Seq. ID No. 1564, Seq. ID No. 1572, Seq. ID No. 1580, Seq. ID No. 1584, Seq. ID No. 1586, Seq. ID No. 1622, Seq. ID No. 1634, Seq. ID No. 1640, Seq. ID No. 1644, Seq. ID No. 1646, Seq. ID No. 1648, Seq. ID No. 1650, Seq. ID No. 1654, Seq. ID No. 1662, Seq. ID No. 1664, Seq. ID No. 1666, Seq. ID No. 1672, Seq. ID No. 1674, Seq. ID No. 1678, Seq. ID No. 1680, Seq. ID No. 1682, Seq. ID No. 1694, Seq. ID No. 1708, Seq. ID No. 1712, Seq. ID No. 1732, Seq. ID No. 1734, Seq. ID No. 1738, Seq. ID No. 1754, Seq. ID No. 1756, Seq. ID No. 1758, Seq. ID No. 1766, Seq. ID No. 1768, Seq. ID No. 1772, Seq. ID No. 1782, Seq. ID No. 1788, Seq. ID No. 1792, Seq. ID No. 1798, Seq. ID No. 1806, Seq. ID No. 1820, Seq. ID No. 1822, Seq. ID No. 1824, Seq. ID No. 1840, Seq. ID No. 1858, Seq. ID No. 1870, Seq. ID No. 1876, Seq. ID No. 1892, Seq. ID No. 1894, Seq. ID No. 1896, Seq. ID No. 1916, Seq. ID No. 1918, Seq. ID No. 1920, Seq. ID No. 1924, Seq. ID No. 1928, Seq. ID No. 1930, Seq. ID No. 1970, Seq. ID No. 1982, Seq. ID No. 1992, Seq. ID No. 1994, Seq. ID No. 2006, Seq. ID No. 2014, Seq. ID No. 2018, Seq. ID No. 2020, Seq. ID No. 2026, Seq. ID No. 2028, Seq. ID No. 2034, Seq. ID No. 2036, Seq. ID No. 2042, Seq. ID No. 2050, Seq. ID No. 2054, Seq. ID No. 2056, Seq. ID No. 2088, Seq. ID No. 2090, Seq. ID No. 2092, Seq. ID No. 2106, Seq. ID No. 2108, Seq. ID No. 2110, Seq. ID No. 2114, Seq. ID No. 2116, Seq. ID No. 2122, Seq. ID No. 2124, Seq. ID No. 2126, Seq. ID No. 2128, Seq. ID No. 2150, Seq. ID No. 2152, Seq. ID No. 2156, Seq. ID No. 2158, Seq. ID No. 2160, Seq. ID No. 2172, Seq. ID No. 2174, Seq. ID No. 2178, Seq. ID No. 2188, Seq. ID No. 2192, Seq. ID No. 2206, Seq. ID No. 2238, Seq. ID No. 2240, Seq. ID No. 2246, Seq. ID No. 2250, Seq. ID No. 2252, Seq. ID No. 2256, Seq. ID No. 2260, Seq. ID No. 2272, Seq. ID No. 2284, Seq. ID No. 2290, Seq. ID No. 2292, Seq. ID No. 2294, Seq. ID No. 2296, Seq. ID No. 2304, Seq. ID No. 2306, Seq. ID No. 2308, Seq. ID No. 2318, Seq. ID No. 2320, Seq. ID No. 2322, Seq. ID No. 2324, Seq. ID No. 2326, Seq. ID No. 2328, Seq. ID No. 2330, Seq. ID No. 2334, Seq. ID No. 2344, Seq. ID No. 2348, Seq. ID No. 2350, Seq. ID No. 2352, Seq. ID No. 2354, Seq. ID No. 2356, Seq. ID No. 2358, Seq. ID No. 2366, Seq. ID No. 2368, Seq. ID No. 2372, Seq. ID No. 2376, Seq. ID No. 2388, Seq. ID No. 2390, Seq. ID No. 2392, Seq. ID No. 2394, Seq. ID No. 2408, Seq. ID No. 2420, Seq. ID No. 2422, Seq. ID No. 2426, Seq. ID No. 2428, Seq. ID No. 2430, Seq. ID No. 2434, Seq. ID No. 2450, Seq. ID No. 2460, Seq. ID No. 2488, Seq. ID No. 2490, Seq. ID No. 2492, Seq. ID No. 2494, Seq. ID No. 2498, Seq. ID No. 2500, Seq. ID No. 2502, Seq. ID No. 2504, Seq. ID No. 2508, Seq. ID No. 2516, Seq. ID No. 2518, Seq. ID No. 2524, Seq. ID No. 2526, Seq. ID No. 2528, Seq. ID No. 2532, Seq. ID No. 2534, Seq. ID No. 2536, Seq. ID No. 2538, Seq. ID No. 2542, Seq. ID No. 2544, Seq. ID No. 2546, Seq. ID No. 2556, Seq. ID No. 2558, Seq. ID No. 2566, Seq. ID No. 2570, Seq. ID No. 2572, Seq. ID No. 2584, Seq. ID No. 2592, Seq. ID No. 2598, Seq. ID No. 2600, Seq. ID No. 2602, Seq. ID No. 2608, Seq. ID No. 2612, Seq. ID No. 2622, Seq. ID No. 2628, Seq. ID No. 2630, Seq. ID No. 2652, Seq. ID No. 2680, Seq. ID No. 2682, Seq. ID No. 2684, Seq. ID No. 2692, Seq. ID No. 2694, Seq. ID No. 2696, Seq. ID No. 2698, Seq. ID No. 2700, Seq. ID No. 2702, Seq. ID No. 2704, Seq. ID No. 2706, Seq. ID No. 2708, Seq. ID No. 2718, Seq. ID No. 2730, Seq. ID No. 2732, Seq. ID No. 2734, Seq. ID No. 2784, Seq. ID No. 2786, Seq. ID No. 2802, Seq. ID No. 2810, Seq. ID No. 2814, Seq. ID No. 2816, Seq. ID No. 2820, Seq. ID No. 2822, Seq. ID No. 2824, Seq. ID No. 2832, Seq. ID No. 2834, Seq. ID No. 2836, Seq. ID No. 2838, Seq. ID No. 2840, Seq. ID No. 2842, Seq. ID No. 2846, Seq. ID No. 2854, Seq. ID No. 2856, Seq. ID No. 2860, Seq. ID No. 2862, Seq. ID No. 2874, Seq. ID No. 2882, Seq. ID No. 2894, Seq. ID No. 2906, Seq. ID No. 2936, Seq. ID No. 2938, Seq. ID No. 2940, Seq. ID No. 2942, Seq. ID No. 2948, Seq. ID No. 2950, Seq. ID No. 2952, Seq. ID No. 2970, Seq. ID No. 2974, Seq. ID No. 2976, Seq. ID No. 2978, Seq. ID No. 2982, Seq. ID No. 2984, Seq. ID No. 2988, Seq. ID No. 2992, Seq. ID No. 2996, Seq. ID No. 2998, Seq. ID No. 3006, Seq. ID No. 3008, Seq. ID No. 3010, Seq. ID No. 3012, Seq. ID No. 3014, Seq. ID No. 3024, Seq. ID No. 3026, Seq. ID No. 3028, Seq. ID No. 3030, Seq. ID No. 3032, Seq. ID No. 3044, Seq. ID No. 3056, Seq. ID No. 3064, Seq. ID No. 3072, Seq. ID No. 3074, Seq. ID No. 3076, Seq. ID No. 3078, Seq. ID No. 3120, Seq. ID No. 3122, Seq. ID No. 3124, Seq. ID No. 3146, Seq. ID No. 3156, Seq. ID No. 3158, Seq. ID No. 3164, Seq. ID No. 3166, Seq. ID No. 3174, Seq. ID No. 3184, Seq. ID No. 3194, Seq. ID No. 3202, Seq. ID No. 3214, Seq. ID No. 3216, Seq. ID No. 3218, Seq. ID No. 3220, Seq. ID No. 3242, Seq. ID No. 3244, Seq. ID No. 3246, Seq. ID No. 3250, Seq. ID No. 3256, Seq. ID No. 3258, Seq. ID No. 3262, Seq. ID No. 3264, Seq. ID No. 3270, Seq. ID No. 3276, Seq. ID No. 3278, Seq. ID No. 3298, Seq. ID No. 3318, Seq. ID No. 3324, Seq. ID No. 3326, Seq. ID No. 3332, Seq. ID No. 3336, Seq. ID No. 3338, Seq. ID No. 3340, Seq. ID No. 3350, Seq. ID No. 3352, Seq. ID No. 3354, Seq. ID No. 3356, Seq. ID No. 3358, Seq. ID No. 3360, Seq. ID No. 3376, Seq. ID No. 3378, Seq. ID No. 3390, Seq. ID No. 3392, Seq. ID No. 3396, Seq. ID No. 3406, Seq. ID No. 3416, Seq. ID No. 3422, Seq. ID No. 3426, Seq. ID No. 3428, Seq. ID No. 3434, Seq. ID No. 3442, Seq. ID No. 3450, Seq. ID No. 3452, Seq. ID No. 3454, Seq. ID No. 3456, Seq. ID No. 3458, Seq. ID No. 3464, Seq. ID No. 3482, Seq. ID No. 3492, Seq. ID No. 3494, Seq. ID No. 3504, Seq. ID No. 3506, Seq. ID No. 3518, Seq. ID No. 3520, Seq. ID No. 3528, Seq. ID No. 3532, Seq. ID No. 3540, Seq. ID No. 3562, Seq. ID No. 3574, Seq. ID No. 3582, Seq. ID No. 3588, Seq. ID No. 3594, Seq. ID No. 3596, Seq. ID No. 3612, Seq. ID No. 3618, Seq. ID No. 3620, Seq. ID No. 3622, Seq. ID No. 3626, Seq. ID No. 3630, Seq. ID No. 3636, Seq. ID No. 3678, Seq. ID No. 3680, Seq. ID No. 3690, Seq. ID No. 3718, Seq. ID No. 3724, Seq. ID No. 3728, Seq. ID No. 3742, Seq. ID No. 3746, Seq. ID No. 3754, Seq. ID No. 3756, Seq. ID No. 3758, Seq. ID No. 3762, Seq. ID No. 3764, Seq. ID No. 3766, Seq. ID No. 3782, Seq. ID No. 3784, Seq. ID No. 3794, Seq. ID No. 3800, Seq. ID No. 3808, Seq. ID No. 3814, Seq. ID No. 3816, Seq. ID No. 3818, Seq. ID No. 3838, Seq. ID No. 3840, Seq. ID No. 3850, Seq. ID No. 3852, Seq. ID No. 3854, Seq. ID No. 3860, Seq. ID No. 3862, Seq. ID No. 3864, Seq. ID No. 3866, Seq. ID No. 3880, Seq. ID No. 3890, Seq. ID No. 3892, Seq. ID No. 3896, Seq. ID No. 3904, Seq. ID No. 3916, Seq. ID No. 3924, Seq. ID No. 3926, Seq. ID No. 3960, Seq. ID No. 3964, Seq. ID No. 3974, Seq. ID No. 3976, Seq. ID No. 3994, Seq. ID No. 3996, Seq. ID No. 3998, Seq. ID No. 4006, Seq. ID No. 4008, Seq. ID No. 4010, Seq. ID No. 4026, Seq. ID No. 4028, Seq. ID No. 4040, Seq. ID No. 4042, Seq. ID No. 4044, Seq. ID No. 4046, Seq. ID No. 4048, Seq. ID No. 4050, Seq. ID No. 4062, Seq. ID No. 4072, Seq. ID No. 4074, Seq. ID No. 4080, Seq. ID No. 4082, Seq. ID No. 4084, Seq. ID No. 4102, Seq. ID No. 4104, Seq. ID No. 4112, Seq. ID No. 4134, Seq. ID No. 4136, Seq. ID No. 4138, Seq. ID No. 4140, Seq. ID No. 4142, Seq. ID No. 4144, Seq. ID No. 4146, Seq. ID No. 4152, Seq. ID No. 4154, Seq. ID No. 4182, Seq. ID No. 4222, Seq. ID No. 4224, Seq. ID No. 4226, Seq. ID No. 4228, Seq. ID No. 4232, Seq. ID No. 4234, Seq. ID No. 4242, Seq. ID No. 4248, Seq. ID No. 4254, Seq. ID No. 4258, Seq. ID No. 4260, Seq. ID No. 4262, Seq. ID No. 4264, Seq. ID No. 4266, Seq. ID No. 4270, Seq. ID No. 4276, Seq. ID No. 4286, Seq. ID No. 4288, Seq. ID No. 4298, Seq. ID No. 4308, Seq. ID No. 4312, Seq. ID No. 4314, Seq. ID No. 4344, Seq. ID No. 4380, Seq. ID No. 4386, Seq. ID No. 4390, Seq. ID No. 4392, Seq. ID No. 4400, Seq. ID No. 4404, Seq. ID No. 4438, Seq. ID No. 4440, Seq. ID No. 4442, Seq. ID No. 4470, Seq. ID No. 4474, Seq. ID No. 4482, Seq. ID No. 4484, Seq. ID No. 4486, Seq. ID No. 4494, Seq. ID No. 4496, Seq. ID No. 4498, Seq. ID No. 4514, Seq. ID No. 4516, Seq. ID No. 4528, Seq. ID No. 4530, Seq. ID No. 4534, Seq. ID No. 4588, Seq. ID No. 4590, Seq. ID No. 4640, Seq. ID No. 4642, Seq. ID No. 4644, Seq. ID No. 4660, Seq. ID No. 4682, Seq. ID No. 4688, Seq. ID No. 4696, Seq. ID No. 4706, Seq. ID No. 4708, Seq. ID No. 4710, Seq. ID No. 4712, Seq. ID No. 4716, Seq. ID No. 4718, Seq. ID No. 4738, Seq. ID No. 4760, Seq. ID No. 4814, Seq. ID No. 4828, Seq. ID No. 4854, Seq. ID No. 4864, Seq. ID No. 4870, Seq. ID No. 4872, Seq. ID No. 4874, Seq. ID No. 4876, Seq. ID No. 4920, Seq. ID No. 4922, Seq. ID No. 4924, Seq. ID No. 4930, Seq. ID No. 4932, Seq. ID No. 4950, Seq. ID No. 4952, Seq. ID No. 4976, Seq. ID No. 4988, Seq. ID No. 5000, Seq. ID No. 5014, Seq. ID No. 5032, Seq. ID No. 5062, Seq. ID No. 5064, Seq. ID No. 5070, Seq. ID No. 5086, Seq. ID No. 5104, Seq. ID No. 5116, Seq. ID No. 5124, Seq. ID No. 5126, Seq. ID No. 5130, Seq. ID No. 5132, Seq. ID No. 5134, Seq. ID No. 5136, Seq. ID No. 5138, Seq. ID No. 5140, Seq. ID No. 5142, Seq. ID No. 5160, Seq. ID No. 5166, Seq. ID No. 5176, Seq. ID No. 5198, Seq. ID No. 5200, Seq. ID No. 5206, Seq. ID No. 5208, Seq. ID No. 5214, Seq. ID No. 5220, Seq. ID No. 5224, Seq. ID No. 5268, Seq. ID No. 5274, Seq. ID No. 5276, Seq. ID No. 5278, Seq. ID No. 5280, Seq. ID No. 5282, Seq. ID No. 5286, Seq. ID No. 5328, Seq. ID No. 5330, Seq. ID No. 5332, Seq. ID No. 5342, Seq. ID No. 5378, Seq. ID No. 5380, Seq. ID No. 5386, Seq. ID No. 5388, Seq. ID No. 5406, Seq. ID No. 5414, Seq. ID No. 5416, Seq. ID No. 5434, Seq. ID No. 5454, Seq. ID No. 5460, Seq. ID No. 5462, Seq. ID No. 5464, Seq. ID No. 5466, Seq. ID No. 5492, Seq. ID No. 5498, Seq. ID No. 5510, Seq. ID No. 5514, Seq. ID No. 5516, Seq. ID No. 5518, Seq. ID No. 5526, Seq. ID No. 5530, Seq. ID No. 5532, Seq. ID No. 5534, Seq. ID No. 5544, Seq. ID No. 5546, Seq. ID No. 5570, Seq. ID No. 5588, Seq. ID No. 5590, Seq. ID No. 5592, Seq. ID No. 5594, Seq. ID No. 5596, Seq. ID No. 5598, Seq. ID No. 5610, Seq. ID No. 5612, Seq. ID No. 5622, Seq. ID No. 5624, Seq. ID No. 5626, Seq. ID No. 5634, Seq. ID No. 5638, Seq. ID No. 5640, Seq. ID No. 5642, Seq. ID No. 5644, Seq. ID No. 5650, Seq. ID No. 5660, Seq. ID No. 5668, Seq. ID No. 5682, Seq. ID No. 5684, Seq. ID No. 5686, Seq. ID No. 5688, Seq. ID No. 5690, Seq. ID No. 5700, Seq. ID No. 5704, Seq. ID No. 5706, Seq. ID No. 5710, Seq. ID No. 5712, Seq. ID No. 5720, Seq. ID No. 5730, Seq. ID No. 5734, Seq. ID No. 5736, Seq. ID No. 5740, Seq. ID No. 5764, Seq. ID No. 5766, Seq. ID No. 5768, Seq. ID No. 5772, Seq. ID No. 5784, Seq. ID No. 5786, Seq. ID No. 5792, Seq. ID No. 5798, Seq. ID No. 5830, Seq. ID No. 5880, Seq. ID No. 5884, Seq. ID No. 5886, Seq. ID No. 5890, Seq. ID No. 5894, Seq. ID No. 5896, Seq. ID No. 5900, Seq. ID No. 5902, Seq. ID No. 5906, Seq. ID No. 5910, Seq. ID No. 5922, Seq. ID No. 5924, Seq. ID No. 5928, Seq. ID No. 5930, Seq. ID No. 5940, Seq. ID No. 6024, Seq. ID No. 6026, Seq. ID No. 6028, Seq. ID No. 6044, Seq. ID No. 6048, Seq. ID No. 6054, Seq. ID No. 6060, Seq. ID No. 6064, Seq. ID No. 6068, Seq. ID No. 6088, Seq. ID No. 6090, Seq. ID No. 6092, Seq. ID No. 6096, Seq. ID No. 6104, Seq. ID No. 6108, Seq. ID No. 6110, Seq. ID No. 6112, Seq. ID No. 6116, Seq. ID No. 6118, Seq. ID No. 6136, Seq. ID No. 6138, Seq. ID No. 6160, Seq. ID No. 6162, Seq. ID No. 6164, Seq. ID No. 6166, Seq. ID No. 6170, Seq. ID No. 6184, Seq. ID No. 6186, Seq. ID No. 6188, Seq. ID No. 6190, Seq. ID No. 6192, Seq. ID No. 6198, Seq. ID No. 6204, Seq. ID No. 6206, Seq. ID No. 6210, Seq. ID No. 6218, Seq. ID No. 6222, Seq. ID No. 6224, Seq. ID No. 6226, Seq. ID No. 6228, Seq. ID No. 6230, Seq. ID No. 6236, Seq. ID No. 6238, Seq. ID No. 6242, Seq. ID No. 6244, Seq. ID No. 6246, Seq. ID No. 6250, Seq. ID No. 6254, Seq. ID No. 6260, Seq. ID No. 6264, Seq. ID No. 6266, Seq. ID No. 6268, Seq. ID No. 6274, Seq. ID No. 6276, Seq. ID No. 6284, Seq. ID No. 6286, Seq. ID No. 6290, Seq. ID No. 6302, Seq. ID No. 6304, Seq. ID No. 6326, Seq. ID No. 6328, Seq. ID No. 6364, Seq. ID No. 6366, Seq. ID No. 6378, Seq. ID No. 6382, Seq. ID No. 6384, Seq. ID No. 6416, Seq. ID No. 6426, Seq. ID No. 6428, Seq. ID No. 6430, Seq. ID No. 6432, Seq. ID No. 6474, Seq. ID No. 6480, Seq. ID No. 6498, Seq. ID No. 6518, Seq. ID No. 6542, Seq. ID No. 6544, Seq. ID No. 6556, Seq. ID No. 6558, Seq. ID No. 6572, Seq. ID No. 6574, Seq. ID No. 6582, Seq. ID No. 6594, Seq. ID No. 6596, Seq. ID No. 6598, Seq. ID No. 6600, Seq. ID No. 6602, Seq. ID No. 6604, Seq. ID No. 6632, Seq. ID No. 6638, Seq. ID No. 6640, Seq. ID No. 6644, Seq. ID No. 6646, and Seq. ID No. 6650.

In yet another embodiment, the Alloiococcus otitidis polypeptide is one that is predicted by HMM SignalP algorithm analysis as being a non-secretory protein, and is selected from one of Seq. ID No. 2, Seq. ID No. 6, Seq. ID No. 12, Seq. ID No. 14, Seq. ID No. 16, Seq. ID No. 18, Seq. ID No. 24, Seq. ID No. 26, Seq. ID No. 28, Seq. ID No. 30, Seq. ID No. 36, Seq. ID No. 38, Seq. ID No. 40, Seq. ID No. 42, Seq. ID No. 44, Seq. ID No. 52, Seq. ID No. 56, Seq. ID No. 58, Seq. ID No. 60, Seq. ID No. 62, Seq. ID No. 64, Seq. ID No. 70, Seq. ID No. 72, Seq. ID No. 74, Seq. ID No. 76, Seq. ID No. 78, Seq. ID No. 80, Seq. ID No. 82, Seq. ID No. 84, Seq. ID No. 90, Seq. ID No. 92, Seq. ID No. 94, Seq. ID No. 96, Seq. ID No. 98, Seq. ID No. 100, Seq. ID No. 102, Seq. ID No. 104, Seq. ID No. 108, Seq. ID No. 110, Seq. ID No. 114, Seq. ID No. 116, Seq. ID No. 118, Seq. ID No. 120, Seq. ID No. 122, Seq. ID No. 126, Seq. ID No. 128, Seq. ID No. 130, Seq. ID No. 136, Seq. ID No. 138, Seq. ID No. 140, Seq. ID No. 144, Seq. ID No. 146, Seq. ID No. 148, Seq. ID No. 150, Seq. ID No. 152, Seq. ID No. 154, Seq. ID No. 156, Seq. ID No. 158, Seq. ID No. 166, Seq. ID No. 168, Seq. ID No. 170, Seq. ID No. 174, Seq. ID No. 176, Seq. ID No. 178, Seq. ID No. 180, Seq. ID No. 182, Seq. ID No. 184, Seq. ID No. 186, Seq. ID No. 188, Seq. ID No. 190, Seq. ID No. 194, Seq. ID No. 196, Seq. ID No. 198, Seq. ID No. 200, Seq. ID No. 202, Seq. ID No. 204, Seq. ID No. 206, Seq. ID No. 208, Seq. ID No. 220, Seq. ID No. 222, Seq. ID No. 224, Seq. ID No. 228, Seq. ID No. 230, Seq. ID No. 232, Seq. ID No. 234, Seq. ID No. 240, Seq. ID No. 242, Seq. ID No. 244, Seq. ID No. 246, Seq. ID No. 248, Seq. ID No. 254, Seq. ID No. 262, Seq. ID No. 264, Seq. ID No. 266, Seq. ID No. 268, Seq. ID No. 270, Seq. ID No. 276, Seq. ID No. 280, Seq. ID No. 282, Seq. ID No. 284, Seq. ID No. 292, Seq. ID No. 294, Seq. ID No. 296, Seq. ID No. 298, Seq. ID No. 300, Seq. ID No. 302, Seq. ID No. 304, Seq. ID No. 306, Seq. ID No. 308, Seq. ID No. 310, Seq. ID No. 312, Seq. ID No. 314, Seq. ID No. 316, Seq. ID No. 318, Seq. ID No. 320, Seq. ID No. 322; Seq. ID No. 324, Seq. ID No. 326, Seq. ID No. 332, Seq. ID No. 334, Seq. ID No. 336, Seq. ID No. 338, Seq. ID No. 340, Seq. ID No. 342, Seq. ID No. 344, Seq. ID No. 346, Seq. ID No. 348, Seq. ID No. 350, Seq. ID No. 352, Seq. ID No. 354, Seq. ID No. 356, Seq. ID No. 362, Seq. ID No. 364, Seq. ID No. 366, Seq. ID No. 368, Seq. ID No. 370, Seq. ID No. 372, Seq. ID No. 378, Seq. ID No. 380, Seq. ID No. 382, Seq. ID No. 384, Seq. ID No. 386, Seq. ID No. 388, Seq. ID No. 390, Seq. ID No. 392, Seq. ID No. 396, Seq. ID No. 398, Seq. ID No. 400, Seq. ID No. 406, Seq. ID No. 408, Seq. ID No. 410, Seq. ID No. 412, Seq. ID No. 414, Seq. ID No. 416, Seq. ID No. 418, Seq. ID No. 420, Seq. ID No. 422, Seq. ID No. 424, Seq. ID No. 426, Seq. ID No. 428, Seq. ID No. 430, Seq. ID No. 432, Seq. ID No. 434, Seq. ID No. 436, Seq. ID No. 438, Seq. ID No. 440, Seq. ID No. 442, Seq. ID No. 444, Seq. ID No. 446, Seq. ID No. 448, Seq. ID No. 450, Seq. ID No. 452, Seq. ID No. 454, Seq. ID No. 460, Seq. ID No. 462, Seq. ID No. 464, Seq. ID No. 466, Seq. ID No. 468, Seq. ID No. 470, Seq. ID No. 472, Seq. ID No. 474, Seq. ID No. 476, Seq. ID No. 480, Seq. ID No. 482, Seq. ID No. 484, Seq. ID No. 486, Seq. ID No. 502, Seq. ID No. 508, Seq. ID No. 518, Seq. ID No. 520, Seq. ID No. 522, Seq. ID No. 524, Seq. ID No. 530, Seq. ID No. 532, Seq. ID No. 534, Seq. ID No. 536, Seq. ID No. 538, Seq. ID No. 540, Seq. ID No. 542, Seq. ID No. 544, Seq. ID No. 552, Seq. ID No. 554, Seq. ID No. 556, Seq. ID No. 560, Seq. ID No. 562, Seq. ID No. 564, Seq. ID No. 566, Seq. ID No. 572, Seq. ID No. 574, Seq. ID No. 582, Seq. ID No. 584, Seq. ID No. 586, Seq. ID No. 588, Seq. ID No. 590, Seq. ID No. 596, Seq. ID No. 598, Seq. ID No. 602, Seq. ID No. 604, Seq. ID No. 606, Seq. ID No. 608, Seq. ID No. 610, Seq. ID No. 612, Seq. ID No. 614, Seq. ID No. 616, Seq. ID No. 620, Seq. ID No. 622, Seq. ID No. 624, Seq. ID No. 626, Seq. ID No. 628, Seq. ID No. 630, Seq. ID No. 632, Seq. ID No. 634, Seq. ID No. 636, Seq. ID No. 650, Seq. ID No. 652, Seq. ID No. 664, Seq. ID No. 666, Seq. ID No. 672, Seq. ID No. 674, Seq. ID No. 682, Seq. ID No. 684, Seq. ID No. 686, Seq. ID No. 688, Seq. ID No. 690, Seq. ID No. 692, Seq. ID No. 694, Seq. ID No. 696, Seq. ID No. 698, Seq. ID No. 700, Seq. ID No. 702, Seq. ID No. 704, Seq. ID No. 706, Seq. ID No. 708, Seq. ID No. 710, Seq. ID No. 712, Seq. ID No. 714, Seq. ID No. 728, Seq. ID No. 730, Seq. ID No. 732, Seq. ID No. 734, Seq. ID No. 736, Seq. ID No. 738, Seq. ID No. 740, Seq. ID No. 742, Seq. ID No. 744, Seq. ID No. 754, Seq. ID No. 768, Seq. ID No. 772, Seq. ID No. 774, Seq. ID No. 776, Seq. ID No. 784, Seq. ID No. 786, Seq. ID No. 788, Seq. ID No. 790, Seq. ID No. 792, Seq. ID No. 794, Seq. ID No. 796, Seq. ID No. 798, Seq. ID No. 800, Seq. ID No. 802, Seq. ID No. 804, Seq. ID No. 806, Seq. ID No. 812, Seq. ID No. 814, Seq. ID No. 816, Seq. ID No. 818, Seq. ID No. 822, Seq. ID No. 824, Seq. ID No. 828, Seq. ID No. 830, Seq. ID No. 832, Seq. ID No. 834, Seq. ID No. 836, Seq. ID No. 838, Seq. ID No. 840, Seq. ID No. 842, Seq. ID No. 844, Seq. ID No. 846, Seq. ID No. 848, Seq. ID No. 850, Seq. ID No. 852, Seq. ID No. 854, Seq. ID No. 856, Seq. ID No. 858, Seq. ID No. 860, Seq. ID No. 862, Seq. ID No. 866, Seq. ID No. 868, Seq. ID No. 870, Seq. ID No. 872, Seq. ID No. 874, Seq. ID No. 876, Seq. ID No. 878, Seq. ID No. 880, Seq. ID No. 882, Seq. ID No. 884, Seq. ID No. 886, Seq. ID No. 888, Seq. ID No. 890, Seq. ID No. 892, Seq. ID No. 896, Seq. ID No. 898, Seq. ID No. 900, Seq. ID No. 904, Seq. ID No. 906, Seq. ID No. 908, Seq. ID No. 910, Seq. ID No. 912, Seq. ID No. 914, Seq. ID No. 916, Seq. ID No. 918, Seq. ID No. 920, Seq. ID No. 922, Seq. ID No. 924, Seq. ID No. 926, Seq. ID No. 928, Seq. ID No. 930, Seq. ID No. 932, Seq. ID No. 934, Seq. ID No. 940, Seq. ID No. 946, Seq. ID No. 948, Seq. ID No. 950, Seq. ID No. 952, Seq. ID No. 954, Seq. ID No. 960, Seq. ID No. 962, Seq. ID No. 964, Seq. ID No. 966, Seq. ID No. 970, Seq. ID No. 972, Seq. ID No. 974, Seq. ID No. 976, Seq. ID No. 978, Seq. ID No. 988, Seq. ID No. 990, Seq. ID No. 992, Seq. ID No. 994, Seq. ID No. 996, Seq. ID No. 998, Seq. ID No. 1000, Seq. ID No. 1018, Seq. ID No. 1022, Seq. ID No. 1024, Seq. ID No. 1026, Seq. ID No. 1028, Seq. ID No. 1042, Seq. ID No. 1044, Seq. ID No. 1048, Seq. ID No. 1050, Seq. ID No. 1052, Seq. ID No. 1054, Seq. ID No. 1058, Seq. ID No. 1060, Seq. ID No. 1062, Seq. ID No. 1064, Seq. ID No. 1066, Seq. ID No. 1068, Seq. ID No. 1070, Seq. ID No. 1072, Seq. ID No. 1074, Seq. ID No. 1080, Seq. ID No. 1082, Seq. ID No. 1084, Seq. ID No. 1086, Seq. ID No. 1088, Seq. ID No. 1090, Seq. ID No. 1092, Seq. ID No. 1094, Seq. ID No. 1096, Seq. ID No. 1098, Seq. ID No. 1100, Seq. ID No. 1102, Seq. ID No. 1104, Seq. ID No. 1110, Seq. ID No. 1112, Seq. ID No. 1114, Seq. ID No. 1116, Seq. ID No. 1118, Seq. ID No. 1120, Seq. ID No. 1122, Seq. ID No. 1124, Seq. ID No. 1126, Seq. ID No. 1128, Seq. ID No. 1130, Seq. ID No. 1134, Seq. ID No. 1142, Seq. ID No. 1144, Seq. ID No. 1146, Seq. ID No. 1148, Seq. ID No. 1150, Seq. ID No. 1154, Seq. ID No. 1156, Seq. ID No. 1158, Seq. ID No. 1160, Seq. ID No. 1162, Seq. ID No. 1164, Seq. ID No. 1172, Seq. ID No. 1176, Seq. ID No. 1178, Seq. ID No. 1180, Seq. ID No. 1182, Seq. ID No. 1186, Seq. ID No. 1188, Seq. ID No. 1190, Seq. ID No. 1192, Seq. ID No. 1194, Seq. ID No. 1200, Seq. ID No. 1202, Seq. ID No. 1206, Seq. ID No. 1208, Seq. ID No. 1210, Seq. ID No. 1212, Seq. ID No. 1216, Seq. ID No. 1218, Seq. ID No. 1220, Seq. ID No. 1222, Seq. ID No. 1226, Seq. ID No. 1232, Seq. ID No. 1234, Seq. ID No. 1236, Seq. ID No. 1240, Seq. ID No. 1242, Seq. ID No. 1248, Seq. ID No. 1250, Seq. ID No. 1252, Seq. ID No. 1254, Seq. ID No. 1256, Seq. ID No. 1258, Seq. ID No. 1262, Seq. ID No. 1264, Seq. ID No. 1274, Seq. ID No. 1276, Seq. ID No. 1278, Seq. ID No. 1280, Seq. ID No. 1282, Seq. ID No. 1286, Seq. ID No. 1294, Seq. ID No. 1300, Seq. ID No. 1302, Seq. ID No. 1308, Seq. ID No. 1310, Seq. ID No. 1312, Seq. ID No. 1314, Seq. ID No. 1322, Seq. ID No. 1324, Seq. ID No. 1334, Seq. ID No. 1336, Seq. ID No. 1340, Seq. ID No. 1346, Seq. ID No. 1356, Seq. ID No. 1358, Seq. ID No. 1360, Seq. ID No. 1362, Seq. ID No. 1364, Seq. ID No. 1374, Seq. ID No. 1376, Seq. ID No. 1378, Seq. ID No. 1380, Seq. ID No. 1384, Seq. ID No. 1386, Seq. ID No. 1388, Seq. ID No. 1390, Seq. ID No. 1392, Seq. ID No. 1394, Seq. ID No. 1396, Seq. ID No. 1398, Seq. ID No. 1400, Seq. ID No. 1404, Seq. ID No. 1406, Seq. ID No. 1408, Seq. ID No. 1410, Seq. ID No. 1412, Seq. ID No. 1414, Seq. ID No. 1416, Seq. ID No. 1418, Seq. ID No. 1420, Seq. ID No. 1422, Seq. ID No. 1424, Seq. ID No. 1426, Seq. ID No. 1428, Seq. ID No. 1432, Seq. ID No. 1434, Seq. ID No. 1438, Seq. ID No. 1440, Seq. ID No. 1442, Seq. ID No. 1444, Seq. ID No. 1450, Seq. ID No. 1452, Seq. ID No. 1454, Seq. ID No. 1456, Seq. ID No. 1458, Seq. ID No. 1460, Seq. ID No. 1462, Seq. ID No. 1464, Seq. ID No. 1466, Seq. ID No. 1468, Seq. ID No. 1470, Seq. ID No. 1472, Seq. ID No. 1474, Seq. ID No. 1476, Seq. ID No. 1478, Seq. ID No. 1480, Seq. ID No. 1484, Seq. ID No. 1486, Seq. ID No. 1488, Seq. ID No. 1490, Seq. ID No. 1492, Seq. ID No. 1494, Seq. ID No. 1496, Seq. ID No. 1498, Seq. ID No. 1500, Seq. ID No. 1502, Seq. ID No. 1504, Seq. ID No. 1506, Seq. ID No. 1508, Seq. ID No. 1510, Seq. ID No. 1512, Seq. ID No. 1520, Seq. ID No. 1522, Seq. ID No. 1524, Seq.-ID No. 1526, Seq. ID No. 1528, Seq. ID No. 1532, Seq. ID No. 1538, Seq. ID No. 1540, Seq. ID No. 1542, Seq. ID No. 1544, Seq. ID No. 1550, Seq. ID No. 1556, Seq. ID No. 1558, Seq. ID No. 1566, Seq. ID No. 1568, Seq. ID No. 1570, Seq. ID No. 1574, Seq. ID No. 1576, Seq. ID No. 1578, Seq. ID No. 1582, Seq. ID No. 1588, Seq. ID No. 1590, Seq. ID No. 1592, Seq. ID No. 1594, Seq. ID No. 1596, Seq. ID No. 1598, Seq. ID No. 1602, Seq. ID No. 1604, Seq. ID No. 1606, Seq. ID No. 1608, Seq. ID No. 1610, Seq. ID No. 1612, Seq. ID No. 1614, Seq. ID No. 1616, Seq. ID No. 1618, Seq. ID No. 1620, Seq. ID No. 1624, Seq. ID No. 1626, Seq. ID No. 1628, Seq. ID No. 1630, Seq. ID No. 1632, Seq. ID No. 1636, Seq. ID No. 1638, Seq. ID No. 1642, Seq. ID No. 1652, Seq. ID No. 1656, Seq. ID No. 1658, Seq. ID No. 1660, Seq. ID No. 1668, Seq. ID No. 1670, Seq. ID No. 1676, Seq. ID No. 1684, Seq. ID No. 1686, Seq. ID No. 1688, Seq. ID No. 1690, Seq. ID No. 1692, Seq. ID No. 1696, Seq. ID No. 1698, Seq. ID No. 1700, Seq. ID No. 1702, Seq. ID No. 1704, Seq. ID No. 1706, Seq. ID No. 1710, Seq. ID No. 1714, Seq. ID No. 1716, Seq. ID No. 1718, Seq. ID No. 1720, Seq. ID No. 1722, Seq. ID No. 1724, Seq. ID No. 1726, Seq. ID No. 1728, Seq. ID No. 1730, Seq. ID No. 1736, Seq. ID No. 1740, Seq. ID No. 1742, Seq. ID No. 1744, Seq. ID No. 1746, Seq. ID No. 1748, Seq. ID No. 1750, Seq. ID No. 1752, Seq. ID No. 1760, Seq. ID No. 1762, Seq. ID No. 1764, Seq. ID No. 1770, Seq. ID No. 1774, Seq. ID No. 1776, Seq. ID No. 1778, Seq. ID No. 1780, Seq. ID No. 1784, Seq. ID No. 1786, Seq. ID No. 1790, Seq. ID No. 1794, Seq. ID No. 1796, Seq. ID No. 1800, Seq. ID No. 1802, Seq. ID No. 1804, Seq. ID No. 1808, Seq. ID No. 1810, Seq. ID No. 1812, Seq. ID No. 1814, Seq. ID No. 1816, Seq. ID No. 1818, Seq. ID No. 1826, Seq. ID No. 1828, Seq. ID No. 1830, Seq. ID No. 1832, Seq. ID No. 1834, Seq. ID No. 1836, Seq. ID No. 1838, Seq. ID No. 1842, Seq. ID No. 1844, Seq. ID No. 1846, Seq. ID No. 1848, Seq. ID No. 1850, Seq. ID No. 1852, Seq. ID No. 1854, Seq. ID No. 1856, Seq. ID No. 1860, Seq. ID No. 1862, Seq. ID No. 1864, Seq. ID No. 1866, Seq. ID No. 1868, Seq. ID No. 1872, Seq. ID No. 1874, Seq. ID No. 1878, Seq. ID No. 1880, Seq. ID No. 1882, Seq. ID No. 1884, Seq. ID No. 1886, Seq. ID No. 1888, Seq. ID No. 1890, Seq. ID No. 1898, Seq. ID No. 1900, Seq. ID No. 1902, Seq. ID No. 1904, Seq. ID No. 1906, Seq. ID No. 1908, Seq. ID No. 1910, Seq. ID No. 1912, Seq. ID No. 1914, Seq. ID No. 1922, Seq. ID No. 1926, Seq. ID No. 1932, Seq. ID No. 1934, Seq. ID No. 1936, Seq. ID No. 1938, Seq. ID No. 1940, Seq. ID No. 1942, Seq. ID No. 1944, Seq. ID No. 1946, Seq. ID No. 1948, Seq. ID No. 1950, Seq. ID No. 1952, Seq. ID No. 1954, Seq. ID No. 1956, Seq. ID No. 1958, Seq. ID No. 1960, Seq. ID No. 1962, Seq. ID No. 1964, Seq. ID No. 1966, Seq. ID No. 1968, Seq. ID No. 1972, Seq. ID No. 1974, Seq. ID No. 1976, Seq. ID No. 1978, Seq. ID No. 1980, Seq. ID No. 1984, Seq. ID No. 1986, Seq. ID No. 1988, Seq. ID No. 1990, Seq. ID No. 1996, Seq. ID No. 1998, Seq. ID No. 2000, Seq. ID No. 2002, Seq. ID No. 2004, Seq. ID No. 2008, Seq. ID No. 2010, Seq. ID No. 2012, Seq. ID No. 2016, Seq. ID No. 2022, Seq. ID No. 2024, Seq. ID No. 2030, Seq. ID No. 2032, Seq. ID No. 2038, Seq. ID No. 2040, Seq. ID No. 2044, Seq. ID No. 2046, Seq. ID No. 2048, Seq. ID No. 2052, Seq. ID No. 2058, Seq. ID No. 2060, Seq. ID No. 2062, Seq. ID No. 2064, Seq. ID No. 2066, Seq. ID No. 2068, Seq. ID No. 2070, Seq. ID No. 2072, Seq. ID No. 2074, Seq. ID No. 2076, Seq. ID No. 2078, Seq. ID No. 2080, Seq. ID No. 2082, Seq. ID No. 2084, Seq. ID No. 2086, Seq. ID No. 2094, Seq. ID No. 2096, Seq. ID No. 2098, Seq. ID No. 2100, Seq. ID No. 2102, Seq. ID No. 2104, Seq. ID No. 2112, Seq. ID No. 2118, Seq. ID No. 2120, Seq. ID No. 2130, Seq. ID No. 2132, Seq. ID No. 2134, Seq. ID No. 2136, Seq. ID No. 2138, Seq. ID No. 2140, Seq. ID No. 2142, Seq. ID No. 2144, Seq. ID No. 2146, Seq. ID No. 2148, Seq. ID No. 2154, Seq. ID No. 2162, Seq. ID No. 2164, Seq. ID No. 2166, Seq. ID No. 2168, Seq. ID No. 2170, Seq. ID No. 2176, Seq. ID No. 2180, Seq. ID No. 2182, Seq. ID No. 2184, Seq. ID No. 2186, Seq. ID No. 2190, Seq. ID No. 2194, Seq. ID No. 2196, Seq. ID No. 2198, Seq. ID No. 2200, Seq. ID No. 2202, Seq. ID No. 2204, Seq. ID No. 2208, Seq. ID No. 2210, Seq. ID No. 2212, Seq. ID No. 2214, Seq. ID No. 2216, Seq. ID No. 2218, Seq. ID No. 2220, Seq. ID No. 2222, Seq. ID No. 2224, Seq. ID No. 2226, Seq. ID No. 2228, Seq. ID No. 2230, Seq. ID No. 2232, Seq. ID No. 2234, Seq. ID No. 2236, Seq. ID No. 2242, Seq. ID No. 2244, Seq. ID No. 2248, Seq. ID No. 2254, Seq. ID No. 2258, Seq. ID No. 2262, Seq. ID No. 2264, Seq. ID No. 2266, Seq. ID No. 2268, Seq. ID No. 2270, Seq. ID No. 2274, Seq. ID No. 2276, Seq. ID No. 2278, Seq. ID No. 2280, Seq. ID No. 2282, Seq. ID No. 2286, Seq. ID No. 2288, Seq. ID No. 2298, Seq. ID No. 2300, Seq. ID No. 2302, Seq. ID No. 2310, Seq. ID No. 2312, Seq. ID No. 2314, Seq. ID No. 2316, Seq. ID No. 2332, Seq. ID No. 2336, Seq. ID No. 2338, Seq. ID No. 2340, Seq. ID No. 2342, Seq. ID No. 2346, Seq. ID No. 2360, Seq. ID No. 2362, Seq. ID No. 2364, Seq. ID No. 2370, Seq. ID No. 2374, Seq. ID No. 2378, Seq. ID No. 2380, Seq. ID No. 2382, Seq. ID No. 2384, Seq. ID No. 2386, Seq. ID No. 2396, Seq. ID No. 2398, Seq. ID No. 2400, Seq. ID No. 2402, Seq. ID No. 2404, Seq. ID No. 2406, Seq. ID No. 2410, Seq. ID No. 2412, Seq. ID No. 2414, Seq. ID No. 2416, Seq. ID No. 2418, Seq. ID No. 2424, Seq. ID No. 2432, Seq. ID No. 2436, Seq. ID No. 2438, Seq. ID No. 2440, Seq. ID No. 2442, Seq. ID No. 2444, Seq. ID No. 2446, Seq. ID No. 2448, Seq. ID No. 2452, Seq. ID No. 2454, Seq. ID No. 2456, Seq. ID No. 2458, Seq. ID No. 2462, Seq. ID No. 2464, Seq. ID No. 2466, Seq. ID No. 2468, Seq. ID No. 2470, Seq. ID No. 2472, Seq. ID No. 2474, Seq. ID No. 2476, Seq. ID No. 2478, Seq. ID No. 2480, Seq. ID No. 2482, Seq. ID No. 2484, Seq. ID No. 2486, Seq. ID No. 2496, Seq. ID No. 2506, Seq. ID No. 2510, Seq. ID No. 2512, Seq. ID No. 2514, Seq. ID No. 2520, Seq. ID No. 2522, Seq. ID No. 2530, Seq. ID No. 2540, Seq. ID No. 2548, Seq. ID No. 2550, Seq. ID No. 2552, Seq. ID No. 2554, Seq. ID No. 2560, Seq. ID No. 2562, Seq. ID No. 2564, Seq. ID No. 2568, Seq. ID No. 2574, Seq. ID No. 2576, Seq. ID No. 2578, Seq. ID No. 2580, Seq. ID No. 2582, Seq. ID No. 2586, Seq. ID No. 2588, Seq. ID No. 2590, Seq. ID No. 2594, Seq. ID No. 2596, Seq. ID No. 2604, Seq. ID No. 2606, Seq. ID No. 2610, Seq. ID No. 2614, Seq. ID No. 2616, Seq. ID No. 2618, Seq. ID No. 2620, Seq. ID No. 2624, Seq. ID No. 2626, Seq. ID No. 2632, Seq. ID No. 2634, Seq. ID No. 2636, Seq. ID No. 2638, Seq. ID No. 2640, Seq. ID No. 2642, Seq. ID No. 2644, Seq. ID No. 2646, Seq. ID No. 2648, Seq. ID No. 2650, Seq. ID No. 2654, Seq. ID No. 2656, Seq. ID No. 2658, Seq. ID No. 2660, Seq. ID No. 2662, Seq. ID No. 2664, Seq. ID No. 2666, Seq. ID No. 2668, Seq. ID No. 2670, Seq. ID No. 2672, Seq. ID No. 2674, Seq. ID No. 2676, Seq. ID No. 2678, Seq. ID No. 2686, Seq. ID No. 2688, Seq. ID No. 2690, Seq. ID No. 2710, Seq. ID No. 2712, Seq. ID No. 2714, Seq. ID No. 2716, Seq. ID No. 2720, Seq. ID No. 2722, Seq. ID No. 2724, Seq. ID No. 2726, Seq. ID No. 2728, Seq. ID No. 2736, Seq. ID No. 2738, Seq. ID No. 2740, Seq. ID No. 2742, Seq. ID No. 2744, Seq. ID No. 2746, Seq. ID No. 2748, Seq. ID No. 2750, Seq. ID No. 2752, Seq. ID No. 2754, Seq. ID No. 2756, Seq. ID No. 2758, Seq. ID No. 2760, Seq. ID No. 2762, Seq. ID No. 2764, Seq. ID No. 2766, Seq. ID No. 2768, Seq. ID No. 2770, Seq. ID No. 2772, Seq. ID No. 2774, Seq. ID No. 2776, Seq. ID No. 2778, Seq. ID No. 2780, Seq. ID No. 2782, Seq. ID No. 2788, Seq. ID No. 2790, Seq. ID No. 2792, Seq. ID No. 2794, Seq. ID No. 2796, Seq. ID No. 2798, Seq. ID No. 2800, Seq. ID No. 2804, Seq. ID No. 2806, Seq. ID No. 2808, Seq. ID No. 2812, Seq. ID No. 2818, Seq. ID No. 2826, Seq. ID No. 2828, Seq. ID No. 2830, Seq. ID No. 2844, Seq. ID No. 2848, Seq. ID No. 2850, Seq. ID No. 2852, Seq. ID No. 2858, Seq. ID No. 2864, Seq. ID No. 2866, Seq. ID No. 2868, Seq. ID No. 2870, Seq. ID No. 2872, Seq. ID No. 2876, Seq. ID No. 2878, Seq. ID No. 2880, Seq. ID No. 2884, Seq. ID No. 2886, Seq. ID No. 2888, Seq. ID No. 2890, Seq. ID No. 2892, Seq. ID No. 2896, Seq. ID No. 2898, Seq. ID No. 2900, Seq. ID No. 2902, Seq. ID No. 2904, Seq. ID No. 2908, Seq. ID No. 2910, Seq. ID No. 2912, Seq. ID No. 2914, Seq. ID No. 2916, Seq. ID No. 2918, Seq. ID No. 2920, Seq. ID No. 2922, Seq. ID No. 2924, Seq. ID No. 2926, Seq. ID No. 2928, Seq. ID No. 2930, Seq. ID No. 2932, Seq. ID No. 2934, Seq. ID No. 2944, Seq. ID No. 2946, Seq. ID No. 2954, Seq. ID No. 2956, Seq. ID No. 2958, Seq. ID No. 2960, Seq. ID No. 2962, Seq. ID No. 2964, Seq. ID No. 2966, Seq. ID No. 2968, Seq. ID No. 2972, Seq. ID No. 2980, Seq. ID No. 2986, Seq. ID No. 2990, Seq. ID No. 2994, Seq. ID No. 3000, Seq. ID No. 3002, Seq. ID No. 3004, Seq. ID No. 3016, Seq. ID No. 3018, Seq. ID No. 3020, Seq. ID No. 3022, Seq. ID No. 3034, Seq. ID No. 3036, Seq. ID No. 3038, Seq. ID No. 3040, Seq. ID No. 3042, Seq. ID No. 3046, Seq. ID No. 3048, Seq. ID No. 3050, Seq. ID No. 3052, Seq. ID No. 3054, Seq. ID No. 3058, Seq. ID No. 3060, Seq. ID No. 3062, Seq. ID No. 3066, Seq. ID No. 3068, Seq. 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ID No. 4842, Seq. ID No. 4844, Seq. ID No. 4846, Seq. ID No. 4848, Seq. ID No. 4850, Seq. ID No. 4852, Seq. ID No. 4856, Seq. ID No. 4858, Seq. ID No. 4860, Seq. ID No. 4862, Seq. ID No. 4866, Seq. ID No. 4868, Seq. ID No. 4878, Seq. ID No. 4880, Seq. ID No. 4882, Seq. ID No. 4884, Seq. ID No. 4886, Seq. ID No. 4888, Seq. ID No. 4890, Seq. ID No. 4892, Seq. ID No. 4894, Seq. ID No. 4896, Seq. ID No. 4898, Seq. ID No. 4900, Seq. ID No. 4902, Seq. ID No. 4904, Seq. ID No. 4906, Seq. ID No. 4908, Seq. ID No. 4910, Seq. ID No. 4912, Seq. ID No. 4914, Seq. ID No. 4916, Seq. ID No. 4918, Seq. ID No. 4926, Seq. ID No. 4928, Seq. ID No. 4934, Seq. ID No. 4936, Seq. ID No. 4938, Seq. ID No. 4940, Seq. ID No. 4942, Seq. ID No. 4944, Seq. ID No. 4946, Seq. ID No. 4948, Seq. ID No. 4954, Seq. ID No. 4956, Seq. ID No. 4958, Seq. ID No. 4960, Seq. ID No. 4962, Seq. ID No. 4964, Seq. ID No. 4966, Seq. ID No. 4968, Seq. ID No. 4970, Seq. ID No. 4972, Seq. ID No. 4974, Seq. ID No. 4978, Seq. ID No. 4980, Seq. ID No. 4982, Seq. ID No. 4984, Seq. ID No. 4986, Seq. ID No. 4990, Seq. ID No. 4992, Seq. ID No. 4994, Seq. ID No. 4996, Seq. ID No. 4998, Seq. ID No. 5002, Seq. ID No. 5004, Seq. ID No. 5006, Seq. ID No. 5008, Seq. ID No. 5010, Seq. ID No. 5012, Seq. ID No. 5016, Seq. ID No. 5018, Seq. ID No. 5020, Seq. ID No. 5022, Seq. ID No. 5024, Seq. ID No. 5026, Seq. ID No. 5028, Seq. ID No. 5030, Seq. ID No. 5034, Seq. ID No. 5036, Seq. ID No. 5038, Seq. ID No. 5040, Seq. ID No. 5042, Seq. ID No. 5044, Seq. ID No. 5046, Seq. ID No. 5048, Seq. ID No. 5050, Seq. ID No. 5052, Seq. ID No. 5054, Seq. ID No. 5056, Seq. ID No. 5058, Seq. ID No. 5060, Seq. ID No. 5066, Seq. ID No. 5068, Seq. ID No. 5072, Seq. ID No. 5074, Seq. ID No. 5076, Seq. ID No. 5078, Seq. ID No. 5080, Seq. ID No. 5082, Seq. ID No. 5084, Seq. ID No. 5088, Seq. ID No. 5090, Seq. ID No. 5092, Seq. ID No. 5094, Seq. ID No. 5096, Seq. ID No. 5098, Seq. ID No. 5100, Seq. ID No. 5102, Seq. ID No. 5106, Seq. ID No. 5108, Seq. ID No. 5110, Seq. ID No. 5112, Seq. ID No. 5114, Seq. ID No. 5118, Seq. ID No. 5120, Seq. ID No. 5122, Seq. ID No. 5128, Seq. ID No. 5144, Seq. ID No. 5146, Seq. ID No. 5148, Seq. ID No. 5150, Seq. ID No. 5152, Seq. ID No. 5154, Seq. ID No. 5156, Seq. ID No. 5158, Seq. ID No. 5162, Seq. ID No. 5164, Seq. ID No. 5168, Seq. ID No. 5170, Seq. ID No. 5172, Seq. ID No. 5174, Seq. ID No. 5178, Seq. ID No. 5180, Seq. ID No. 5182, Seq. ID No. 5184, Seq. ID No. 5186, Seq. ID No. 5188, Seq. ID No. 5190, Seq. ID No. 5192, Seq. ID No. 5194, Seq. ID No. 5196, Seq. ID No. 5202, Seq. ID No. 5204, Seq. ID No. 5210, Seq. ID No. 5212, Seq. ID No. 5216, Seq. ID No. 5218, Seq. ID No. 5222, Seq. ID No. 5226, Seq. ID No. 5228, Seq. ID No. 5230, Seq. ID No. 5232, Seq. ID No. 5234, Seq. ID No. 5236, Seq. ID No. 5238, Seq. ID No. 5240, Seq. ID No. 5242, Seq. ID No. 5244, Seq. ID No. 5246, Seq. ID No. 5248, Seq. ID No. 5250, Seq. ID No. 5252, Seq. ID No. 5254, Seq. ID No. 5256, Seq. ID No. 5258, Seq. ID No. 5260, Seq. ID No. 5262, Seq. ID No. 5264, Seq. ID No. 5266, Seq. ID No. 5270, Seq. ID No. 5272, Seq. ID No. 5284, Seq. ID No. 5288, Seq. ID No. 5290, Seq. ID No. 5292, Seq. ID No. 5294, Seq. ID No. 5296, Seq. ID No. 5298, Seq. ID No. 5300, Seq. ID No. 5302, Seq. ID No. 5304, Seq. ID No. 5306, Seq. ID No. 5308, Seq. ID No. 5310, Seq. ID No. 5312, Seq. ID No. 5314, Seq. ID No. 5316, Seq. ID No. 5318, Seq. ID No. 5320, Seq. ID No. 5322, Seq. ID No. 5324, Seq. ID No. 5326, Seq. ID No. 5334, Seq. ID No. 5336, Seq. ID No. 5338, Seq. ID No. 5340, Seq. ID No. 5344, Seq. ID No. 5346, Seq. ID No. 5348, Seq. ID No. 5350, Seq. ID No. 5352, Seq. ID No. 5354, Seq. ID No. 5356, Seq. ID No. 5358, Seq. ID No. 5360, Seq. ID No. 5362, Seq. ID No. 5364, Seq. ID No. 5366, Seq. ID No. 5368, Seq. ID No. 5370, Seq. ID No. 5372, Seq. ID No. 5374, Seq. ID No. 5376, Seq. ID No. 5382, Seq. ID No. 5384, Seq. ID No. 5390, Seq. ID No. 5392, Seq. ID No. 5394, Seq. ID No. 5396, Seq. ID No. 5398, Seq. ID No. 5400, Seq. ID No. 5402, Seq. ID No. 5404, Seq. ID No. 5408, Seq. ID No. 5410, Seq. ID No. 5412, Seq. ID No. 5418, Seq. ID No. 5420, Seq. ID No. 5422, Seq. ID No. 5424, Seq. ID No. 5426, Seq. ID No. 5428, Seq. ID No. 5430, Seq. ID No. 5432, Seq. ID No. 5436, Seq. ID No. 5438, Seq. ID No. 5440, Seq. ID No. 5442, Seq. ID No. 5444, Seq. ID No. 5446, Seq. ID No. 5448, Seq. ID No. 5450, Seq. ID No. 5452, Seq. ID No. 5456, Seq. ID No. 5458, Seq. ID No. 5468, Seq. ID No. 5470, Seq. ID No. 5472, Seq. ID No. 5474, Seq. ID No. 5476, Seq. ID No. 5478, Seq. ID No. 5480, Seq. ID No. 5482, Seq. ID No. 5484, Seq. ID No. 5486, Seq. ID No. 5488, Seq. ID No. 5490, Seq. ID No. 5494, Seq. ID No. 5496, Seq. ID No. 5500, Seq. ID No. 5502, Seq. ID No. 5504, Seq. ID No. 5506, Seq. ID No. 5508, Seq. ID No. 5512, Seq. ID No. 5520, Seq. ID No. 5522, Seq. ID No. 5524, Seq. ID No. 5528, Seq. ID No. 5536, Seq. ID No. 5538, Seq. ID No. 5540, Seq. ID No. 5542, Seq. ID No. 5548, Seq. ID No. 5550, Seq. ID No. 5552, Seq. ID No. 5554, Seq. ID No. 5556, Seq. ID No. 5558, Seq. ID No. 5560, Seq. ID No. 5562, Seq. ID No. 5564, Seq. ID No. 5566, Seq. ID No. 5568, Seq. ID No. 5572, Seq. ID No. 5574, Seq. ID No. 5576, Seq. ID No. 5578, Seq. ID No. 5580, Seq. ID No. 5582, Seq. ID No. 5584, Seq. ID No. 5586, Seq. ID No. 5600, Seq. ID No. 5602, Seq. ID No. 5604, Seq. ID No. 5606, Seq. ID No. 5608, Seq. ID No. 5614, Seq. ID No. 5616, Seq. ID No. 5618, Seq. ID No. 5620, Seq. ID No. 5628, Seq. ID No. 5630, Seq. ID No. 5632, Seq. ID No. 5636, Seq. ID No. 5646, Seq. ID No. 5648, Seq. ID No. 5652, Seq. ID No. 5654, Seq. ID No. 5656, Seq. ID No. 5658, Seq. ID No. 5662, Seq. ID No. 5664, Seq. ID No. 5666, Seq. ID No. 5670, Seq. ID No. 5672, Seq. ID No. 5674, Seq. ID No. 5676, Seq. ID No. 5678, Seq. ID No. 5680, Seq. ID No. 5692, Seq. ID No. 5694, Seq. ID No. 5696, Seq. ID No. 5698, Seq. ID No. 5702, Seq. ID No. 5708, Seq. ID No. 5714, Seq. ID No. 5716, Seq. ID No. 5718, Seq. ID No. 5722, Seq. ID No. 5724, Seq. ID No. 5726, Seq. ID No. 5728, Seq. ID No. 5732, Seq. ID No. 5738, Seq. ID No. 5742, Seq. ID No. 5744, Seq. ID No. 5746, Seq. ID No. 5748, Seq. ID No. 5750, Seq. ID No. 5752, Seq. ID No. 5754, Seq. ID No. 5756, Seq. ID No. 5758, Seq. ID No. 5760, Seq. ID No. 5762, Seq. ID No. 5770, Seq. ID No. 5774, Seq. ID No. 5776, Seq. ID No. 5778, Seq. ID No. 5780, Seq. ID No. 5782, Seq. ID No. 5788, Seq. ID No. 5790, Seq. ID No. 5794, Seq. ID No. 5796, Seq. ID No. 5800, Seq. ID No. 5802, Seq. ID No. 5804, Seq. ID No. 5806, Seq. ID No. 5808, Seq. ID No. 5810, Seq. ID No. 5812, Seq. ID No. 5814, Seq. ID No. 5816, Seq. ID No. 5818, Seq. ID No. 5820, Seq. ID No. 5822, Seq. ID No. 5824, Seq. ID No. 5826, Seq. ID No. 5828, Seq. ID No. 5832, Seq. ID No. 5834, Seq. ID No. 5836, Seq. ID No. 5838, Seq. ID No. 5840, Seq. ID No. 5842, Seq. ID No. 5844, Seq. ID No. 5846, Seq. ID No. 5848, Seq. ID No. 5850, Seq. ID No. 5852, Seq. ID No. 5854, Seq. ID No. 5856, Seq. ID No. 5858, Seq. ID No. 5860, Seq. ID No. 5862, Seq. ID No. 5864, Seq. ID No. 5866, Seq. ID No. 5868, Seq. ID No. 5870, Seq. ID No. 5872, Seq. ID No. 5874, Seq. ID No. 5876, Seq. ID No. 5878, Seq. ID No. 5882, Seq. ID No. 5888, Seq. ID No. 5892, Seq. ID No. 5898, Seq. ID No. 5904, Seq. ID No. 5908, Seq. ID No. 5912, Seq. ID No. 5914, Seq. ID No. 5916, Seq. ID No. 5918, Seq. ID No. 5920, Seq. ID No. 5926, Seq. ID No. 5932, Seq. ID No. 5934, Seq. ID No. 5936, Seq. ID No. 5938, Seq. ID No. 5942, Seq. ID No. 5944, Seq. ID No. 5946, Seq. ID No. 5948, Seq. ID No. 5950, Seq. ID No. 5952, Seq. ID No. 5954, Seq. ID No. 5956, Seq. ID No. 5958, Seq. ID No. 5960, Seq. ID No. 5962, Seq. ID No. 5964, Seq. ID No. 5966, Seq. ID No. 5968, Seq. ID No. 5970, Seq. ID No. 5972, Seq. ID No. 5974, Seq. ID No. 5976, Seq. ID No. 5978, Seq. ID No. 5980, Seq. ID No. 5982, Seq. ID No. 5984, Seq. ID No. 5986, Seq. ID No. 5988, Seq. ID No. 5990, Seq. ID No. 5992, Seq. ID No. 5994, Seq. ID No. 5996, Seq. ID No. 5998, Seq. ID No. 6000, Seq. ID No. 6002, Seq. ID No. 6004, Seq. ID No. 6006, Seq. ID No. 6008, Seq. ID No. 6010, Seq. ID No. 6012, Seq. ID No. 6014, Seq. ID No. 6016, Seq. ID No. 6018, Seq. ID No. 6020, Seq. ID No. 6022, Seq. ID No. 6030, Seq. ID No. 6032, Seq. ID No. 6034, Seq. ID No. 6036, Seq. ID No. 6038, Seq. ID No. 6040, Seq. ID No. 6042, Seq. ID No. 6046, Seq. ID No. 6050, Seq. ID No. 6052, Seq. ID No. 6056, Seq. ID No. 6058, Seq. ID No. 6062, Seq. ID No. 6066, Seq. ID No. 6070, Seq. ID No. 6072, Seq. ID No. 6074, Seq. ID No. 6076, Seq. ID No. 6078, Seq. ID No. 6080, Seq. ID No. 6082, Seq. ID No. 6084, Seq. ID No. 6086, Seq. ID No. 6094, Seq. ID No. 6098, Seq. ID No. 6100, Seq. ID No. 6102, Seq. ID No. 6106, Seq. ID No. 6114, Seq. ID No. 6120, Seq. ID No. 6122, Seq. ID No. 6124, Seq. ID No. 6126, Seq. ID No. 6128, Seq. ID No. 6130, Seq. ID No. 6132, Seq. ID No. 6134, Seq. ID No. 6140, Seq. ID No. 6142, Seq. ID No. 6144, Seq. ID No. 6146, Seq. ID No. 6148, Seq. ID No. 6150, Seq. ID No. 6152, Seq. ID No. 6154, Seq. ID No. 6156, Seq. ID No. 6158, Seq. ID No. 6168, Seq. ID No. 6172, Seq. ID No. 6174, Seq. ID No. 6176, Seq. ID No. 6178, Seq. ID No. 6180, Seq. ID No. 6182, Seq. ID No. 6194, Seq. ID No. 6196, Seq. ID No. 6200, Seq. ID No. 6202, Seq. ID No. 6208, Seq. ID No. 6212, Seq. ID No. 6214, Seq. ID No. 6216, Seq. ID No. 6220, Seq. ID No. 6232, Seq. ID No. 6234, Seq. ID No. 6240, Seq. ID No. 6248, Seq. ID No. 6252, Seq. ID No. 6256, Seq. ID No. 6258, Seq. ID No. 6262, Seq. ID No. 6270, Seq. ID No. 6272, Seq. ID No. 6278, Seq. ID No. 6280, Seq. ID No. 6282, Seq. ID No. 6288, Seq. ID No. 6292, Seq. ID No. 6294, Seq. ID No. 6296, Seq. ID No. 6298, Seq. ID No. 6300, Seq. ID No. 6306, Seq. ID No. 6308, Seq. ID No. 6310, Seq. ID No. 6312, Seq. ID No. 6314, Seq. ID No. 6316, Seq. ID No. 6313, Seq. ID No. 6320, Seq. ID No. 6322, Seq. ID No. 6324, Seq. ID No. 6330, Seq. ID No. 6332, Seq. ID No. 6334, Seq. ID No. 6336, Seq. ID No. 6338, Seq. ID No. 6340, Seq. ID No. 6342, Seq. ID No. 6344, Seq. ID No. 6346, Seq. ID No. 6348, Seq. ID No. 6350, Seq. ID No. 6352, Seq. ID No. 6354, Seq. ID No. 6356, Seq. ID No. 6358, Seq. ID No. 6360, Seq. ID No. 6362, Seq. ID No. 6368, Seq. ID No. 6370, Seq. ID No. 6372, Seq. ID No. 6374, Seq. ID No. 6376, Seq. ID No. 6380, Seq. ID No. 6386, Seq. ID No. 6388, Seq. ID No. 6390, Seq. ID No. 6392, Seq. ID No. 6394, Seq. ID No. 6396, Seq. ID No. 6398, Seq. ID No. 6400, Seq. ID No. 6402, Seq. ID No. 6404, Seq. ID No. 6406, Seq. ID No. 6408, Seq. ID No. 6410, Seq. ID No. 6412, Seq. ID No. 6414, Seq. ID No. 6418, Seq. ID No. 6420, Seq. ID No. 6422, Seq. ID No. 6424, Seq. ID No. 6434, Seq. ID No. 6436, Seq. ID No. 6438, Seq. ID No. 6440, Seq. ID No. 6442, Seq. ID No. 6444, Seq. ID No. 6446, Seq. ID No. 6448, Seq. ID No. 6450, Seq. ID No. 6452, Seq. ID No. 6454, Seq. ID No. 6456, Seq. ID No. 6458, Seq. ID No. 6460, Seq. ID No. 6462, Seq. ID No. 6464, Seq. ID No. 6466, Seq. ID No. 6468, Seq. ID No. 6470, Seq. ID No. 6472, Seq. ID No. 6476, Seq. ID No. 6478, Seq. ID No. 6482, Seq. ID No. 6484, Seq. ID No. 6486, Seq. ID No. 6488, Seq. ID No. 6490, Seq. ID No. 6492, Seq. ID No. 6494, Seq. ID No. 6496, Seq. ID No. 6500, Seq. ID No. 6502, Seq. ID No. 6504, Seq. ID No. 6506, Seq. ID No. 6508, Seq. ID No. 6510, Seq. ID No. 6512, Seq. ID No. 6514, Seq. ID No. 6516, Seq. ID No. 6520, Seq. ID No. 6522, Seq. ID No. 6524, Seq. ID No. 6526, Seq. ID No. 6528, Seq. ID No. 6530, Seq. ID No. 6532, Seq. ID No. 6534, Seq. ID No. 6536, Seq. ID No. 6538, Seq. ID No. 6540, Seq. ID No. 6546, Seq. ID No. 6548, Seq. ID No. 6550, Seq. ID No. 6552, Seq. ID No. 6554, Seq. ID No. 6560, Seq. ID No. 6562, Seq. ID No. 6564, Seq. ID No. 6566, Seq. ID No. 6568, Seq. ID No. 6570, Seq. ID No. 6576, Seq. ID No. 6578, Seq. ID No. 6580, Seq. ID No. 6584, Seq. ID No. 6586, Seq. ID No. 6588, Seq. ID No. 6590, Seq. ID No. 6592, Seq. ID No. 6606, Seq. ID No. 6608, Seq. ID No. 6610, Seq. ID No. 6612, Seq. ID No. 6614, Seq. ID No. 6616, Seq. ID No. 6618, Seq. ID No. 6620, Seq. ID No. 6622, Seq. ID No. 6624, Seq. ID No. 6626, Seq. ID No. 6628, Seq. ID No. 6630, Seq. ID No. 6634, Seq. ID No. 6636, Seq. ID No. 6642, and Seq. ID No. 6648.

In another preferred embodiment, the polypeptide is selected from the Alloiococcus otitidis polypeptides identified by BlastP analysis and is selected from one of Seq. ID No. 10, Seq. ID No. 18, Seq. ID No. 46, Seq. ID No. 50, Seq. ID No. 54, Seq. ID No. 60, Seq. ID No. 90, Seq. ID No. 146, Seq. ID No. 158, Seq. ID No. 168, Seq. ID No. 172, Seq. ID No. 192, Seq. ID No. 216, Seq. ID No. 218, Seq. ID No. 226, Seq. ID No. 240, Seq. ID No. 254, Seq. ID No. 274, Seq. ID No. 278, Seq. ID No. 290, Seq. ID No. 330, Seq. ID No. 344, Seq. ID No. 346, Seq. ID No. 376, Seq. ID No. 502, Seq. ID No. 506, Seq. ID No. 512, Seq. ID No. 516, Seq. ID No. 530, Seq. ID No. 570, Seq. ID No. 576, Seq. ID No. 594, Seq. ID No. 596, Seq. ID No. 638, Seq. ID No. 660, Seq. ID No. 670, Seq. ID No. 676, Seq. ID No. 682, Seq. ID No. 730, Seq. ID No. 780, Seq. ID No. 820, Seq. ID No. 896, Seq. ID No. 922, Seq. ID No. 936, Seq. ID No. 956, Seq. ID No. 968, Seq. ID No. 986, Seq. ID No. 1018, Seq. ID No. 1040, Seq. ID No. 1076, Seq. ID No. 1090, Seq. ID No. 1138, Seq. ID No. 1224, Seq. ID No. 1242, Seq. ID No. 1316, Seq. ID No. 1332, Seq. ID No. 1370, Seq. ID No. 1460, Seq. ID No. 1518, Seq. ID No. 1562, Seq. ID No. 1564, Seq. ID No. 1568, Seq. ID No. 1572, Seq. ID No. 1574, Seq. ID No. 1602, Seq. ID No. 1608, Seq. ID No. 1614, Seq. ID No. 1620, Seq. ID No. 1642, Seq. ID No. 1648, Seq. ID No. 1654, Seq. ID No. 1658, Seq. ID No. 1666, Seq. ID No. 1700, Seq. ID No. 1714, Seq. ID No. 1752, Seq. ID No. 1772, Seq. ID No. 1786, Seq. ID No. 1790, Seq. ID No. 1792, Seq. ID No. 1798, Seq. ID No. 1812, Seq. ID No. 1818, Seq. ID No. 1820, Seq. ID No. 1822, Seq. ID No. 1872, Seq. ID No. 1896, Seq. ID No. 1906, Seq. ID No. 1914, Seq. ID No. 1920, Seq. ID No. 1924, Seq. ID No. 1966, Seq. ID No. 1972, Seq. ID No. 2000, Seq. ID No. 2048, Seq. ID No. 2056, Seq. ID No. 2092, Seq. ID No. 2094, Seq. ID No. 2116, Seq. ID No. 2120, Seq. ID No. 2128, Seq. ID No. 2166, Seq. ID No. 2180, Seq. ID No. 2208, Seq. ID No. 2224, Seq. ID No. 2228, Seq. ID No. 2242, Seq. ID No. 2254, Seq. ID No. 2264, Seq. ID No. 2270, Seq. ID No. 2276, Seq. ID No. 2302, Seq. ID No. 2316, Seq. ID No. 2330, Seq. ID No. 2334, Seq. ID No. 2344, Seq. ID No. 2346, Seq. ID No. 2364, Seq. ID No. 2374, Seq. ID No. 2392, Seq. ID No. 2418, Seq. ID No. 2430, Seq. ID No. 2466, Seq. ID No. 2476, Seq. ID No. 2484, Seq. ID No. 2514, Seq. ID No. 2526, Seq. ID No. 2590, Seq. ID No. 2614, Seq. ID No. 2652, Seq. ID No. 2670, Seq. ID No. 2678, Seq. ID No. 2688, Seq. ID No. 2690, Seq. ID No. 2694, Seq. ID No. 2704, Seq. ID No. 2710, Seq. ID No. 2716, Seq. ID No. 2752, Seq. ID No. 2754, Seq. ID No. 2768, Seq. ID No. 2788, Seq. ID No. 2792, Seq. ID No. 2804, Seq. ID No. 2868, Seq. ID No. 2872, Seq. ID No. 2908, Seq. ID No. 2920, Seq. ID No. 2922, Seq. ID No. 2924, Seq. ID No. 2928, Seq. ID No. 2934, Seq. ID No. 2958, Seq. ID No. 2980, Seq. ID No. 3000, Seq. ID No. 3006, Seq. ID No. 3020, Seq. ID No. 3032, Seq. ID No. 3036, Seq. ID No. 3056, Seq. ID No. 3068, Seq. ID No. 3086, Seq. ID No. 3166, Seq. ID No. 3184, Seq. ID No. 3190, Seq. ID No. 3198, Seq. ID No. 3212, Seq. ID No. 3252, Seq. ID No. 3258, Seq. ID No. 3260, Seq. ID No. 3298, Seq. ID No. 3320, Seq. ID No. 3324, Seq. ID No. 3336, Seq. ID No. 3338, Seq. ID No. 3356, Seq. ID No. 3360, Seq. ID No. 3378, Seq. ID No. 3398, Seq. ID No. 3406, Seq. ID No. 3416, Seq. ID No. 3426, Seq. ID No. 3428, Seq. ID No. 3462, Seq. ID No. 3464, Seq. ID No. 3488, Seq. ID No. 3494, Seq. ID No. 3498, Seq. ID No. 3508, Seq. ID No. 3520, Seq. ID No. 3522, Seq. ID No. 3530, Seq. ID No. 3536, Seq. ID No. 3630, Seq. ID No. 3636, Seq. ID No. 3728, Seq. ID No. 3760, Seq. ID No. 3772, Seq. ID No. 3794, Seq. ID No. 3840, Seq. ID No. 3852, Seq. ID No. 3864, Seq. ID No. 3866, Seq. ID No. 3884, Seq. ID No. 3892, Seq. ID No. 3914, Seq. ID No. 3926, Seq. ID No. 3930, Seq. ID No. 3976, Seq. ID No. 3982, Seq. ID No. 4028, Seq. ID No. 4040, Seq. ID No. 4062, Seq. ID No. 4074, Seq. ID No. 4082, Seq. ID No. 4104, Seq. ID No. 4112, Seq. ID No. 4138, Seq. ID No. 4226, Seq. ID No. 4248, Seq. ID No. 4344, Seq. ID No. 4380, Seq. ID No. 4390, Seq. ID No. 4470, Seq. ID No. 4474, Seq. ID No. 4482, Seq. ID No. 4486, Seq. ID No. 4494, Seq. ID No. 4530, Seq. ID No. 4644, Seq. ID No. 4706, Seq. ID No. 4714, Seq. ID No. 4718, Seq. ID No. 4814, Seq. ID No. 4816, Seq. ID No. 4826, Seq. ID No. 4828, Seq. ID No. 4834, Seq. ID No. 4838, Seq. ID No. 4852, Seq. ID No. 4864, Seq. ID No. 4876, Seq. ID No. 4880, Seq. ID No. 4894, Seq. ID No. 4902, Seq. ID No. 4920, Seq. ID No. 4932, Seq. ID No. 4960, Seq. ID No. 4964, Seq. ID No. 4986, Seq. ID No. 5114, Seq. ID No. 5116, Seq. ID No. 5118, Seq. ID No. 5126, Seq. ID No. 5142, Seq. ID No. 5184, Seq. ID No. 5202, Seq. ID No. 5206, Seq. ID No. 5214, Seq. ID No. 5220, Seq. ID No. 5280, Seq. ID No. 5286, Seq. ID No. 5332, Seq. ID No. 5382, Seq. ID No. 5390, Seq. ID No. 5406, Seq. ID No. 5412, Seq. ID No. 5420, Seq. ID No. 5434, Seq. ID No. 5464, Seq. ID No. 5478, Seq. ID No. 5492, Seq. ID No. 5510, Seq. ID No. 5514, Seq. ID No. 5526, Seq. ID No. 5530, Seq. ID No. 5538, Seq. ID No. 5568, Seq. ID No. 5600, Seq. ID No. 5622, Seq. ID No. 5638, Seq. ID No. 5700, Seq. ID No. 5724, Seq. ID No. 5734, Seq. ID No. 5762, Seq. ID No. 5792, Seq. ID No. 5896, Seq. ID No. 5902, Seq. ID No. 5904, Seq. ID No. 5910, Seq. ID No. 5914, Seq. ID No. 5920, Seq. ID No. 5930, Seq. ID No. 5940, Seq. ID No. 6002, Seq. ID No. 6044, Seq. ID No. 6054, Seq. ID No. 6058, Seq. ID No. 6090, Seq. ID No. 6096, Seq. ID No. 6104, Seq. ID No. 6112, Seq. ID No. 6118, Seq. ID No. 6166, Seq. ID No. 6170, Seq. ID No. 6186, Seq. ID No. 6192, Seq. ID No. 6210, Seq. ID No. 6230, Seq. ID No. 6258, Seq. ID No. 6264, Seq. ID No. 6272, Seq. ID No. 6276, Seq. ID No. 6290, Seq. ID No. 6304, Seq. ID No. 6366, Seq. ID No. 6370, Seq. ID No. 6384, and Seq. ID No. 6416.

In another preferred embodiment, the polypeptide is selected from the Alloiococcus otitidis polypeptides, which have been identified by Pfam analysis, and is selected from one of Seq. ID No. 90, Seq. ID No. 146, Seq. ID No. 156, Seq. ID No. 168, Seq. ID No. 174, Seq. ID No. 192, Seq. ID No. 216, Seq. ID No. 220, Seq. ID No. 222, Seq. ID No. 224, Seq. ID No. 226, Seq. ID No. 234, Seq. ID No. 240, Seq. ID No. 252, Seq. ID No. 254, Seq. ID No. 272, Seq. ID No. 292, Seq. ID No. 332, Seq. ID No. 342, Seq. ID No. 346, Seq. ID No. 376, Seq. ID No. 502, Seq. ID No. 506, Seq. ID No. 512, Seq. ID No. 530, Seq. ID No. 568, Seq. ID No. 570, Seq. ID No. 576, Seq. ID No. 594, Seq. ID No. 596, Seq. ID No. 602, Seq. ID No. 638, Seq. ID No. 650, Seq. ID No. 662, Seq. ID No. 670, Seq. ID No. 676, Seq. ID No. 682, Seq. ID No. 684, Seq. ID No. 730, Seq. ID No. 754, Seq. ID No. 780, Seq. ID No. 828, Seq. ID No. 840, Seq. ID No. 896, Seq. ID No. 940, Seq. ID No. 970, Seq. ID No. 986, Seq. ID No. 1016, Seq. ID No. 1040, Seq. ID No. 1076, Seq. ID No. 1138, Seq. ID No. 1156, Seq. ID No. 1164, Seq. ID No. 1176, Seq. ID No. 1224, Seq. ID No. 1232, Seq. ID No. 1238, Seq. ID No. 1242, Seq. ID No. 1262, Seq. ID No. 1332, Seq. ID No. 1340, Seq. ID No. 1370, Seq. ID No. 1478, Seq. ID No. 1518, Seq. ID No. 1532, Seq. ID No. 1540, Seq. ID No. 1550, Seq. ID No. 1564, Seq. ID No. 1568, Seq. ID No. 1572, Seq. ID No. 1574, Seq. ID No. 1590, Seq. ID No. 1596, Seq. ID No. 1648, Seq. ID No. 1658, Seq. ID No. 1772, Seq. ID No. 1786, Seq. ID No. 1790, Seq. ID No. 1820, Seq. ID No. 1822, Seq. ID No. 1970, Seq. ID No. 2016, Seq. ID No. 2048, Seq. ID No. 2088, Seq. ID No. 2090, Seq. ID No. 2094, Seq. ID No. 2116, Seq. ID No. 2118, Seq. ID No. 2128, Seq. ID No. 2142, Seq. ID No. 2180, Seq. ID No. 2208, Seq. ID No. 2224, Seq. ID No. 2254, Seq. ID No. 2276, Seq. ID No. 2302, Seq. ID No. 2316, Seq. ID No. 2330, Seq. ID No. 2344, Seq. ID No. 2350, Seq. ID No. 2364, Seq. ID No. 2382, Seq. ID No. 2392, Seq. ID No. 2418, Seq. ID No. 2422, Seq. ID No. 2424, Seq. ID No. 2430, Seq. ID No. 2482, Seq. ID No. 2488, Seq. ID No. 2490, Seq. ID No. 2492, Seq. ID No. 2510, Seq. ID No. 2520, Seq. ID No. 2526, Seq. ID No. 2548, Seq. ID No. 2554, Seq. ID No. 2564, Seq. ID No. 2588, Seq. ID No. 2600, Seq. ID No. 2608, Seq. ID No. 2614, Seq. ID No. 2652, Seq. ID No. 2676, Seq. ID No. 2682, Seq. ID No. 2688, Seq. ID No. 2694, Seq. ID No. 2700, Seq. ID No. 2704, Seq. ID No. 2710, Seq. ID No. 2712, Seq. ID No. 2728, Seq. ID No. 2754, Seq. ID No. 2820, Seq. ID No. 2822, Seq. ID No. 2824, Seq. ID No. 2868, Seq. ID No. 2872, Seq. ID No. 2908, Seq. ID No. 2920, Seq. ID No. 2958, Seq. ID No. 2972, Seq. ID No. 2980, Seq. ID No. 3000, Seq. ID No. 3006, Seq. ID No. 3020, Seq. ID No. 3036, Seq. ID No. 3066, Seq. ID No. 3086, Seq. ID No. 3150, Seq. ID No. 3166, Seq. ID No. 3184, Seq. ID No. 3204, Seq. ID No. 3212, Seq. ID No. 3252, Seq. ID No. 3260, Seq. ID No. 3320, Seq. ID No. 3324, Seq. ID No. 3336, Seq. ID No. 3338, Seq. ID No. 3348, Seq. ID No. 3360, Seq. ID No. 3378, Seq. ID No. 3380, Seq. ID No. 3400, Seq. ID No. 3426, Seq. ID No. 3484, Seq. ID No. 3496, Seq. ID No. 3498, Seq. ID No. 3520, Seq. ID No. 3530, Seq. ID No. 3600, Seq. ID No. 3612, Seq. ID No. 3616, Seq. ID No. 3620, Seq. ID No. 3664, Seq. ID No. 3740, Seq. ID No. 3760, Seq. ID No. 3772, Seq. ID No. 3798, Seq. ID No. 3826, Seq. ID No. 3842, Seq. ID No. 3856, Seq. ID No. 3864, Seq. ID No. 3902, Seq. ID No. 3930, Seq. ID No. 4016, Seq. ID No. 4018, Seq. ID No. 4056, Seq. ID No. 4076, Seq. ID No. 4086, Seq. ID No. 4090, Seq. ID No. 4100, Seq. ID No. 4106, Seq. ID No. 4130, Seq. ID No. 4204, Seq. ID No. 4244, Seq. ID No. 4252, Seq. ID No. 4344, Seq. ID No. 4384, Seq. ID No. 4476, Seq. ID No. 4482, Seq. ID No. 4488, Seq. ID No. 4492, Seq. ID No. 4534, Seq. ID No. 4628, Seq. ID No. 4706, Seq. ID No. 4714, Seq. ID No. 4718, Seq. ID No. 4720, Seq. ID No. 4730, Seq. ID No. 4790, Seq. ID No. 4792, Seq. ID No. 4794, Seq. ID No. 4804, Seq. ID No. 4814, Seq. ID No. 4816, Seq. ID No. 4826, Seq. ID No. 4834, Seq. ID No. 4838, Seq. ID No. 4876, Seq. ID No. 4880, Seq. ID No. 4920, Seq. ID No. 4932, Seq. ID No. 4948, Seq. ID No. 4986, Seq. ID No. 5078, Seq. ID No. 5116, Seq. ID No. 5118, Seq. ID No. 5128, Seq. ID No. 5142, Seq. ID No. 5194, Seq. ID No. 5216, Seq. ID No. 5220, Seq. ID No. 5276, Seq. ID No. 5382, Seq. ID No. 5390, Seq. ID No. 5410, Seq. ID No. 5412, Seq. ID No. 5476, Seq. ID No. 5492, Seq. ID No. 5514, Seq. ID No. 5520, Seq. ID No. 5526, Seq. ID No. 5530, Seq. ID No. 5538, Seq. ID No. 5558, Seq. ID No. 5582, Seq. ID No. 5600, Seq. ID No. 5638, Seq. ID No. 5686, Seq. ID No. 5724, Seq. ID No. 5756, Seq. ID No. 5762, Seq. ID No. 5896, Seq. ID No. 5902, Seq. ID No. 5904, Seq. ID No. 5912, Seq. ID No. 5914, Seq. ID No. 5920, Seq. ID No. 5924, Seq. ID No. 5930, Seq. ID No. 6002, Seq. ID No. 6044, Seq. ID No. 6054, Seq. ID No. 6056, Seq. ID No. 6090, Seq. ID No. 6096, Seq. ID No. 6112, Seq. ID No. 6118, Seq. ID No. 6166, Seq. ID No. 6170, Seq. ID No. 6188, Seq. ID No. 6196, Seq. ID No. 6220, Seq. ID No. 6234, Seq. ID No. 6270, Seq. ID No. 6276, Seq. ID No. 6280, Seq. ID No. 6288, Seq. ID No. 6298, Seq. ID No. 6300, Seq. ID No. 6306, Seq. ID No. 6312, Seq. ID No. 6370, Seq. ID No. 6380, Seq. ID No. 6588, and Seq. ID No. 6592.

In yet another preferred embodiment, the polypeptide is selected from the Alloiococcus otitidis polypeptides, wherein the polypeptide is identified using proteomics methodology as sharing homology with surface exposed proteins in Streptococcus pneumoniae, and is selected from one of Seq. ID No. 2, Seq. ID No. 6, Seq. ID No. 94, Seq. ID No. 96, Seq. ID No. 104, Seq. ID No. 108, Seq. ID No. 158, Seq. ID No. 224, Seq. ID No. 226, Seq. ID No. 234, Seq. ID No. 240, Seq. ID No. 254, Seq. ID No. 318, Seq. ID No. 322, Seq. ID No. 342, Seq. ID No. 346, Seq. ID No. 354, Seq. ID No. 362, Seq. ID No. 364, Seq. ID No. 366, Seq. ID No. 376, Seq. ID No. 380, Seq. ID No. 384, Seq. ID No. 390, Seq. ID No. 392, Seq. ID No. 398, Seq. ID No. 406, Seq. ID No. 410, Seq. ID No. 416, Seq. ID No. 424, Seq. ID No. 426, Seq. ID No. 428, Seq. ID No. 430, Seq. ID No. 436, Seq. ID No. 438, Seq. ID No. 440, Seq. ID No. 442, Seq. ID No. 444, Seq. ID No. 446, Seq. ID No. 448, Seq. ID No. 450, Seq. ID No. 462, Seq. ID No. 464, Seq. ID No. 466, Seq. ID No. 514, Seq. ID No. 544, Seq. ID No. 552, Seq. ID No. 554, Seq. ID No. 560, Seq. ID No. 596, Seq. ID No. 602, Seq. ID No. 638, Seq. ID No. 650, Seq. ID No. 658, Seq. ID No. 670, Seq. ID No. 676, Seq. ID No. 684, Seq. ID No. 754, Seq. ID No. 930, Seq. ID No. 970, Seq. ID No. 1042, Seq. ID No. 1044, Seq. ID No. 1086, Seq. ID No. 1090, Seq. ID No. 1094, Seq. ID No. 1098, Seq. ID No. 1100, Seq. ID No. 1102, Seq. ID No. 1176, Seq. ID No. 1206, Seq. ID No. 1238, Seq. ID No. 1460, Seq. ID No. 1496, Seq. ID No. 1498, Seq. ID No. 1504, Seq. ID No. 1518, Seq. ID No. 1528, Seq. ID No. 1532, Seq. ID No. 1540, Seq. ID No. 1544, Seq. ID No. 1550, Seq. ID No. 1574, Seq. ID No. 1658, Seq. ID No. 1710, Seq. ID No. 1768, Seq. ID No. 1786, Seq. ID No. 1822, Seq. ID No. 1890, Seq. ID No. 1926, Seq. ID No. 1970, Seq. ID No. 2004, Seq. ID No. 2048, Seq. ID No. 2076, Seq. ID No. 2090, Seq. ID No. 2094, Seq. ID No. 2118, Seq. ID No. 2138, Seq. ID No. 2144, Seq. ID No. 2206, Seq. ID No. 2236, Seq. ID No. 2258, Seq. ID No. 2302, Seq. ID No. 2364, Seq. ID No. 2424, Seq. ID No. 2446, Seq. ID No. 2452, Seq. ID No. 2482, Seq. ID No. 2496, Seq. ID No. 2506, Seq. ID No. 2578, Seq. ID No. 2588, Seq. ID No. 2614, Seq. ID No. 2634, Seq. ID No. 2652, Seq. ID No. 2666, Seq. ID No. 2670, Seq. ID No. 2678, Seq. ID No. 2688, Seq. ID No. 2694, Seq. ID No. 2700, Seq. ID No. 2712, Seq. ID No. 2716, Seq. ID No. 2758, Seq. ID No. 2792, Seq. ID No. 2794, Seq. ID No. 2804, Seq. ID No. 2868, Seq. ID No. 2920, Seq. ID No. 2930, Seq. ID No. 3006, Seq. ID No. 3020, Seq. ID No. 3126, Seq. ID No. 3138, Seq. ID No. 3162, Seq. ID No. 3180, Seq. ID No. 3252, Seq. ID No. 3260, Seq. ID No. 3286, Seq. ID No. 3310, Seq. ID No. 3318, Seq. ID No. 3338, Seq. ID No. 3346, Seq. ID No. 3360, Seq. ID No. 3476, Seq. ID No. 3516, Seq. ID No. 3522, Seq. ID No. 3642, Seq. ID No. 3696, Seq. ID No. 3794, Seq. ID No. 3902, Seq. ID No. 3928, Seq. ID No. 3988, Seq. ID No. 4002, Seq. ID No. 4058, Seq. ID No. 4082, Seq. ID No. 4112, Seq. ID No. 4126, Seq. ID No. 4194, Seq. ID No. 4196, Seq. ID No. 4238, Seq. ID No. 4248, Seq. ID No. 4384, Seq. ID No. 4394, Seq. ID No. 4398, Seq. ID No. 4402, Seq. ID No. 4436, Seq. ID No. 4450, Seq. ID No. 4472, Seq. ID No. 4492, Seq. ID No. 4512, Seq. ID No. 4520, Seq. ID No. 4532, Seq. ID No. 4550, Seq. ID No. 4578, Seq. ID No. 4582, Seq. ID No. 4586, Seq. ID No. 4610, Seq. ID No. 4612, Seq. ID No. 4614, Seq. ID No. 4676, Seq. ID No. 4686, Seq. ID No. 4720, Seq. ID No. 4730, Seq. ID No. 4744, Seq. ID No. 4756, Seq. ID No. 4782, Seq. ID No. 4788, Seq. ID No. 4838, Seq. ID No. 4842, Seq. ID No. 4850, Seq. ID No. 4856, Seq. ID No. 4890, Seq. ID No. 4902, Seq. ID No. 4916, Seq. ID No. 4918, Seq. ID No. 4932, Seq. ID No. 4936, Seq. ID No. 4978, Seq. ID No. 5026, Seq. ID No. 5030, Seq. ID No. 5110, Seq. ID No. 5116, Seq. ID No. 5118, Seq. ID No. 5156, Seq. ID No. 5186, Seq. ID No. 5202, Seq. ID No. 5204, Seq. ID No. 5220, Seq. ID No. 5262, Seq. ID No. 5290, Seq. ID No. 5296, Seq. ID No. 5378, Seq. ID No. 5390, Seq. ID No. 5400, Seq. ID No. 5412, Seq. ID No. 5538, Seq. ID No. 5622, Seq. ID No. 5628, Seq. ID No. 5658, Seq. ID No. 5676, Seq. ID No. 5718, Seq. ID No. 5778, Seq. ID No. 5860, Seq. ID No. 5902, Seq. ID No. 5914, Seq. ID No. 5920, Seq. ID No. 5926, Seq. ID No. 5934, Seq. ID No. 6056, Seq. ID No. 6130, Seq. ID No. 6134, Seq. ID No. 6188, Seq. ID No. 6194, Seq. ID No. 6220, Seq. ID No. 6272, Seq. ID No. 6278, Seq. ID No. 6370, Seq. ID No. 6376, Seq. ID No. 6380, Seq. ID No. 6390, Seq. ID No. 6592, and Seq. ID No. 6606.

In yet another preferred embodiment, the polypeptide is selected from the Alloiococcus otitidis polypeptides identified as having an LPXTG motif, which are covalently attached to the peptidoglycan layer, and is selected from one of Seq. ID No. 504, Seq. ID No. 506, Seq. ID No. 1316, Seq. ID No. 1318, Seq. ID No. 1364, Seq. ID No. 1366, Seq. ID No. 1368, Seq. ID No. 1370, Seq. ID No. 1560, Seq. ID No. 1562, Seq. ID No. 1582, Seq. ID No. 1740, Seq. ID No. 1742, Seq. ID No. 2812, Seq. ID No. 2814, Seq. ID No. 3620, Seq. ID No. 5588, Seq. ID No. 5590, Seq. ID No. 5592, Seq. ID No. 5782, Seq. ID No. 5784, and Seq. ID No. 6104.

In yet another preferred embodiment, the polypeptide is selected from the Alloiococcus otitidis polypeptides identified as lipoproteins using the HMM Lipo algorithm, and is selected from one Seq. ID No. 46, Seq. ID No. 48, Seq. ID No. 172, Seq. ID No. 226, Seq. ID No. 420, Seq. ID No. 514, Seq. ID No. 576, Seq. ID No. 592, Seq. ID No. 594, Seq. ID No. 658, Seq. ID No. 660, Seq. ID No. 670, Seq. ID No. 676, Seq. ID No. 746, Seq. ID No. 748, Seq. ID No. 936, Seq. ID No. 1046, Seq. ID No. 1076, Seq. ID No. 1138, Seq. ID No. 1174, Seq. ID No. 1192, Seq. ID No. 1194, Seq. ID No. 1196, Seq. ID No. 1564, Seq. ID No. 1662, Seq. ID No. 1664, Seq. ID No. 1666, Seq. ID No. 1792, Seq. ID No. 1798, Seq. ID No. 1918, Seq. ID No. 1970, Seq. ID No. 2116, Seq. ID No. 2160, Seq. ID No. 2430, Seq. ID No. 2528, Seq. ID No. 2700, Seq. ID No. 2816, Seq. ID No. 2876, Seq. ID No. 2976, Seq. ID No. 2978, Seq. ID No. 2992, Seq. ID No. 3044, Seq. ID No. 3324, Seq. ID No. 3338, Seq. ID No. 4134, Seq. ID No. 4138, Seq. ID No. 4482, Seq. ID No. 4706, Seq. ID No. 4828, Seq. ID No. 4870, Seq. ID No. 5116, Seq. ID No. 5378, Seq. ID No. 5380, Seq. ID No. 5492, Seq. ID No. 5510, Seq. ID No. 5514, Seq. ID No. 5526, Seq. ID No. 5530, Seq. ID No. 5532, Seq. ID No. 5890, Seq. ID No. 5910, Seq. ID No. 6026, Seq. ID No. 6028, Seq. ID No. 6088, Seq. ID No. 6090, Seq. ID No. 6326, Seq. ID No. 6328, Seq. ID No. 6416, Seq. ID No. 6638, Seq. ID No. 6640, and Seq. ID No. 6646.

In yet another preferred embodiment, the polypeptide is selected from the Alloiococcus otitidis polypeptides, wherein the polypeptide is non-covalently associated with the peptidoglycan layer and is selected from one of Seq. ID No. 3590, Seq. ID No. 3988, Seq. ID No. 5220, and Seq. ID No. 5338.

In yet another preferred embodiment, the polypeptide is selected from the Alloiococcus otitidis polypeptides having an RGDX motif wherein X is not a proline residue, and is selected from one of Seq. ID No. 38, Seq. ID No. 100, Seq. ID No. 108, Seq. ID No. 110, Seq. ID No. 112, Seq. ID No. 352, Seq. ID No. 354, Seq. ID No. 466, Seq. ID No. 468, Seq. ID No. 470, Seq. ID No. 472, Seq. ID No. 684, Seq. ID No. 822, Seq. ID No. 824, Seq. ID No. 1022, Seq. ID No. 1024, Seq. ID No. 1158, Seq. ID No. 1160, Seq. ID No. 1234, Seq. ID No. 1334, Seq. ID No. 1336, Seq. ID No. 1450, Seq. ID No. 1560, Seq. ID No. 1562, Seq. ID No. 1564, Seq. ID No. 1626, Seq. ID No. 1778, Seq. ID No. 1828, Seq. ID No. 1830, Seq. ID No. 1872, Seq. ID No. 1926, Seq. ID No. 2136, Seq. ID No. 2146, Seq. ID No. 2174, Seq. ID No. 2176, Seq. ID No. 2178, Seq. ID No. 2180, Seq. ID No. 2260, Seq. ID No. 2318, Seq. ID No. 2320, Seq. ID No. 2322, Seq. ID No. 2324, Seq. ID No. 2326, Seq. ID No. 2328, Seq. ID No. 2330, Seq. ID No. 2402, Seq. ID No. 2672, Seq. ID No. 2864, Seq. ID No. 2870, Seq. ID No. 2920, Seq. ID No. 2922, Seq. ID No. 2994, Seq. ID No. 3088, Seq. ID No. 3138, Seq. ID No. 3280, Seq. ID No. 3282, Seq. ID No. 3284, Seq. ID No. 3334, Seq. ID No. 3336, Seq. ID No. 3498, Seq. ID No. 3500, Seq. ID No. 3502, Seq. ID No. 3534, Seq. ID No. 3672, Seq. ID No. 3674, Seq. ID No. 3676, Seq. ID No. 3838, Seq. ID No. 3840, Seq. ID No. 3842, Seq. ID No. 3844, Seq. ID No. 3930, Seq. ID No. 3962, Seq. ID No. 4038, Seq. ID No. 4194, Seq. ID No. 4240, Seq. ID No. 4328, Seq. ID No. 4330, Seq. ID No. 4334, Seq. ID No. 4394, Seq. ID No. 4464, Seq. ID No. 4466, Seq. ID No. 4468, Seq. ID No. 4598, Seq. ID No. 4630, Seq. ID No. 4632, Seq. ID No. 4676, Seq. ID No. 4678, Seq. ID No. 4680, Seq. ID No. 4690, Seq. ID No. 4692, Seq. ID No. 4694, Seq. ID No. 4782, Seq. ID No. 4800, Seq. ID No. 4802, Seq. ID No. 4804, Seq. ID No. 4862, Seq. ID No. 5010, Seq. ID No. 5144, Seq. ID No. 5146, Seq. ID No. 5180, Seq. ID No. 5182, Seq. ID No. 5184, Seq. ID No. 5250, Seq. ID No. 5252, Seq. ID No. 5254, Seq. ID No. 5260, Seq. ID No. 5262, Seq. ID No. 5294, Seq. ID No. 5296, Seq. ID No. 5298, Seq. ID No. 5300, Seq. ID No. 5308, Seq. ID No. 5310, Seq. ID No. 5412, Seq. ID No. 5536, Seq. ID No. 5538, Seq. ID No. 5746, Seq. ID No. 5822, Seq. ID No. 5824, Seq. ID No. 5826, Seq. ID No. 6030, Seq. ID No. 6172, Seq. ID No. 6308, Seq. ID No. 6310, and Seq. ID No. 6312.

In another preferred embodiment, the polypeptide is selected from Alloiococcus otitidis polypeptides predicted by BlastP as being involved in capsule biosynthesis and transport, and is selected from one of Seq. ID No. 50, Seq. ID No. 52, Seq. ID No. 54, Seq. ID No. 60, Seq. ID No. 196, Seq. ID No. 690, Seq. ID No. 704, Seq. ID No. 926, Seq. ID No. 1598, Seq. ID No. 1602, Seq. ID No. 1608, Seq. ID No. 1612, Seq. ID No. 1614, Seq. ID No. 1714, Seq. ID No. 2030, Seq. ID No. 2264, Seq. ID No. 2270, Seq. ID No. 2374, Seq. ID No. 2438, Seq. ID No. 2652, Seq. ID No. 2768, Seq. ID No. 2908, Seq. ID No. 3398, Seq. ID No. 3400, Seq. ID No. 3480, Seq. ID No. 3488, Seq. ID No. 3492, Seq. ID No. 3494, Seq. ID No. 3496, Seq. ID No. 3498, Seq. ID No. 3520, Seq. ID No. 3522, Seq. ID No. 3530, Seq. ID No. 3536, Seq. ID No. 3562, Seq. ID No. 3884, Seq. ID No. 3892, Seq. ID No. 3982, and Seq. ID No. 4088.

In another preferred embodiment, the polypeptide is selected from Alloiococcus otitidis polypeptides predicted by BlastP as being localized in the capsule loci region of Alloiococcus otitidis, and is selected from one of Seq. ID No. 46, Seq. ID No. 48, Seq. ID No. 52, Seq. ID No. 54, Seq. ID No. 56, Seq. ID No. 58, Seq. ID No. 60, Seq. ID No. 684, Seq. ID No. 686, Seq. ID No. 688, Seq. ID No. 690, Seq. ID No. 692, Seq. ID No. 694, Seq. ID No. 696, Seq. ID No. 698, Seq. ID No. 700, Seq. ID No. 702, Seq. ID No. 704, Seq. ID No. 706, Seq. ID No. 708, Seq. ID No. 710, Seq. ID No. 712, Seq. ID No. 714, Seq. ID No. 716, Seq. ID No. 718, Seq. ID No. 720, Seq. ID No. 722, Seq. ID No. 724, Seq. ID No. 726, Seq. ID No. 728, Seq. ID No. 730, Seq. ID No. 732, Seq. ID No. 734, Seq. ID No. 736, Seq. ID No. 738, Seq. ID No. 740, Seq. ID No. 742, Seq. ID No. 744, Seq. ID No. 746, Seq. ID No. 748, Seq. ID No. 750, Seq. ID No. 752, Seq. ID No. 754, Seq. ID No. 3390, Seq. ID No. 3392, Seq. ID No. 3394, Seq. ID No. 3396, Seq. ID No. 3398, Seq. ID No. 3400, Seq. ID No. 3402, Seq. ID No. 3404, Seq. ID No. 3406, Seq. ID No. 3408, Seq. ID No. 3410, Seq. ID No. 3412, Seq. ID No. 3414, Seq. ID No. 3416, Seq. ID No. 3418, Seq. ID No. 3420, Seq. ID No. 3422, Seq. ID No. 3424, Seq. ID No. 3426, Seq. ID No. 3428, Seq. ID No. 3430, Seq. ID No. 3432, Seq. ID No. 3434, Seq. ID No. 3436, Seq. ID No. 3438, Seq. ID No. 3440, Seq. ID No. 3442, Seq. ID No. 3444, Seq. ID No. 3446, Seq. ID No. 3448, Seq. ID No. 3450, Seq. ID No. 3452, Seq. ID No. 3454, Seq. ID No. 3456, Seq. ID No. 3458, Seq. ID No. 3460, Seq. ID No. 3462, Seq. ID No. 3464, Seq. ID No. 3466, Seq. ID No. 3468, Seq. ID No. 3470, Seq. ID No. 3472, Seq. ID No. 3474, Seq. ID No. 3476, Seq. ID No. 3478, Seq. ID No. 3480, Seq. ID No. 3482, Seq. ID No. 3484, Seq. ID No. 3486, Seq. ID No. 3488, Seq. ID No. 3490, Seq. ID No. 3492, Seq. ID No. 3494, Seq. ID No. 3496, Seq. ID No. 3498, Seq. ID No. 3500, Seq. ID No. 3502, Seq. ID No. 3504, Seq. ID No. 3506, Seq. ID No. 3508, Seq. ID No. 3510, Seq. ID No. 3512, Seq. ID No. 3514, Seq. ID No. 3516, Seq. ID No. 3518, Seq. ID No. 3520, Seq. ID No. 3522, Seq. ID No. 3524, Seq. ID No. 3526, Seq. ID No. 3528, Seq. ID No. 3530, Seq. ID No. 3532, Seq. ID No. 3534, Seq. ID No. 3536, Seq. ID No. 3538, Seq. ID No. 3540, Seq. ID No. 3542, Seq. ID No. 3544, Seq. ID No. 3546, Seq. ID No. 3548, Seq. ID No. 3550, Seq. ID No. 3552, Seq. ID No. 3554, Seq. ID No. 3556, Seq. ID No. 3558, Seq. ID No. 3560, and Seq. ID No. 3562.

In another preferred embodiment, the polypeptide is selected from the Alloiococcus otitidis polypeptides identified by BlastP analysis to be associated with sporulation, and is selected from one of Seq. ID No. 1138, Seq. ID No. 1456, Seq. ID No. 2138, Seq. ID No. 2142, Seq. ID No. 2166, Seq. ID No. 2180, Seq. ID No. 2302, Seq. ID No. 2754, Seq. ID No. 4212, Seq. ID No. 4252, Seq. ID No. 4328, Seq. ID No. 4570, Seq. ID No. 4720, and Seq. ID No. 4730.

In another preferred embodiment, the polypeptide is selected from the Alloiococcus otitidis polypeptides identified by BlastP analysis as being encoded by unique ORFs, and is selected from one of Seq. ID No. 8, Seq. ID No. 20, Seq. ID No. 22, Seq. ID No. 24, Seq. ID No. 32, Seq. ID No. 40, Seq. ID No. 66, Seq. ID No. 68, Seq. ID No. 70, Seq. ID No. 92, Seq. ID No. 100, Seq. ID No. 106, Seq. ID No. 114, Seq. ID No. 116, Seq. ID No. 124, Seq. ID No. 126, Seq. ID No. 128, Seq. ID No. 132, Seq. ID No. 134, Seq. ID No. 140, Seq. ID No. 152, Seq. ID No. 160, Seq. ID No. 162, Seq. ID No. 164, Seq. ID No. 166, Seq. ID No. 170, Seq. ID No. 186, Seq. ID No. 190, Seq. ID No. 194, Seq. ID No. 230, Seq. ID No. 232, Seq. ID No. 256, Seq. ID No. 258, Seq. ID No. 260, Seq. ID No. 276, Seq. ID No. 338, Seq. ID No. 340, Seq. ID No. 348, Seq. ID No. 350, Seq. ID No. 358, Seq. ID No. 360, Seq. ID No. 370, Seq. ID No. 372, Seq. ID No. 378, Seq. ID No. 386, Seq. ID No. 388, Seq. ID No. 394, Seq. ID No. 400, Seq. ID No. 402, Seq. ID No. 404, Seq. ID No. 408, Seq. ID No. 420, Seq. ID No. 432, Seq. ID No. 478, Seq. ID No. 496, Seq. ID No. 508, Seq. ID No. 520, Seq. ID No. 542, Seq. ID No. 546, Seq. ID No. 548, Seq. ID No. 550, Seq. ID No. 558, Seq. ID No. 590, Seq. ID No. 618, Seq. ID No. 620, Seq. ID No. 634, Seq. ID No. 640, Seq. ID No. 642, Seq. ID No. 644, Seq. ID No. 646, Seq. ID No. 648, Seq. ID No. 652, Seq. ID No. 654, Seq. ID No. 656, Seq. ID No. 668, Seq. ID No. 692, Seq. ID No. 694, Seq. ID No. 696, Seq. ID No. 698, Seq. ID No. 716, Seq. ID No. 718, Seq. ID No. 720, Seq. ID No. 732, Seq. ID No. 734, Seq. ID No. 742, Seq. ID No. 744, Seq. ID No. 746, Seq. ID No. 748, Seq. ID No. 750, Seq. ID No. 752, Seq. ID No. 756, Seq. ID No. 758, Seq. ID No. 760, Seq. ID No. 762, Seq. ID No. 764, Seq. ID No. 766, Seq. ID No. 768, Seq. ID No. 802, Seq. ID No. 804, Seq. ID No. 806, Seq. ID No. 808, Seq. ID No. 810, Seq. ID No. 812, Seq. ID No. 814, Seq. ID No. 834, Seq. ID No. 842, Seq. ID No. 850, Seq. ID No. 852, Seq. ID No. 854, Seq. ID No. 856, Seq. ID No. 888, Seq. ID No. 890, Seq. ID No. 892, Seq. ID No. 904, Seq. ID No. 906, Seq. ID No. 910, Seq. ID No. 938, Seq. ID No. 942, Seq. ID No. 944, Seq. ID No. 952, Seq. ID No. 958, Seq. ID No. 974, Seq. ID No. 976, Seq. ID No. 988, Seq. ID No. 1006, Seq. ID No. 1008, Seq. ID No. 1010, Seq. ID No. 1012, Seq. ID No. 1020, Seq. ID No. 1026, Seq. ID No. 1028, Seq. ID No. 1046, Seq. ID No. 1048, Seq. ID No. 1072, Seq. ID No. 1074, Seq. ID No. 1078, Seq. ID No. 1106, Seq. ID No. 1108, Seq. ID No. 1112, Seq. ID No. 1132, Seq. ID No. 1136, Seq. ID No. 1140, Seq. ID No. 1152, Seq. ID No. 1154, Seq. ID No. 1166, Seq. ID No. 1168, Seq. ID No. 1170, Seq. ID No. 1172, Seq. ID No. 1174, Seq. ID No. 1182, Seq. ID No. 1184, Seq. ID No. 1186, Seq. ID No. 1188, Seq. ID No. 1190, Seq. ID No. 1192, Seq. ID No. 1194, Seq. ID No. 1196, Seq. ID No. 1198, Seq. ID No. 1200, Seq. ID No. 1202, Seq. ID No. 1204, Seq. ID No. 1208, Seq. ID No. 1214, Seq. ID No. 1228, Seq. ID No. 1230, Seq. ID No. 1240, Seq. ID No. 1244, Seq. ID No. 1246, Seq. ID No. 1248, Seq. ID No. 1250, Seq. ID No. 1260, Seq. ID No. 1266, Seq. ID No. 1268, Seq. ID No. 1270, Seq. ID No. 1272, Seq. ID No. 1274, Seq. ID No. 1276, Seq. ID No. 1278, Seq. ID No. 1280, Seq. ID No. 1282, Seq. ID No. 1284, Seq. ID No. 1286, Seq. ID No. 1288, Seq. ID No. 1290, Seq. ID No. 1292, Seq. ID No. 1294, Seq. ID No. 1296, Seq. ID No. 1298, Seq. ID No. 1300, Seq. ID No. 1302, Seq. ID No. 1304, Seq. ID No. 1306, Seq. ID No. 1308, Seq. ID No. 1310, Seq. ID No. 1312, Seq. ID No. 1314, Seq. ID No. 1320, Seq. ID No. 1322, Seq. ID No. 1324, Seq. ID No. 1326, Seq. ID No. 1328, Seq. ID No. 1338, Seq. ID No. 1342, Seq. ID No. 1344, Seq. ID No. 1348, Seq. ID No. 1350, Seq. ID No. 1352, Seq. ID No. 1354, Seq. ID No. 1356, Seq. ID No. 1372, Seq. ID No. 1380, Seq. ID No. 1382, Seq. ID No. 1390, Seq. ID No. 1398, Seq. ID No. 1400, Seq. ID No. 1402, Seq. ID No. 1418, Seq. ID No. 1420, Seq. ID No. 1422, Seq. ID No. 1424, Seq. ID No. 1440, Seq. ID No. 1446, Seq. ID No. 1448, Seq. ID No. 1458, Seq. ID No. 1466, Seq. ID No. 1480, Seq. ID No. 1512, Seq. ID No. 1552, Seq. ID No. 1554, Seq. ID No. 1556, Seq. ID No. 1558, Seq. ID No. 1580, Seq. ID No. 1610, Seq. ID No. 1622, Seq. ID No. 1624, Seq. ID No. 1626, Seq. ID No. 1628, Seq. ID No. 1630, Seq. ID No. 1632, Seq. ID No. 1634, Seq. ID No. 1640, Seq. ID No. 1644, Seq. ID No. 1656, Seq. ID No. 1668, Seq. ID No. 1672, Seq. ID No. 1694, Seq. ID No. 1696, Seq. ID No. 1702, Seq. ID No. 1704, Seq. ID No. 1706, Seq. ID No. 1722, Seq. ID No. 1724, Seq. ID No. 1732, Seq. ID No. 1738, Seq. ID No. 1744, Seq. ID No. 1760, Seq. ID No. 1764, Seq. ID No. 1774, Seq. ID No. 1776, Seq. ID No. 1778, Seq. ID No. 1780, Seq. ID No. 1782, Seq. ID No. 1800, Seq. ID No. 1802, Seq. ID No. 1804, Seq. ID No. 1808, Seq. ID No. 1824, Seq. ID No. 1832, Seq. ID No. 1852, Seq. ID No. 1858, Seq. ID No. 1876, Seq. ID No. 1900, Seq. ID No. 1916, Seq. ID No. 1928, Seq. ID No. 1930, Seq. ID No. 1974, Seq. ID No. 1978, Seq. ID No. 1982, Seq. ID No. 2006, Seq. ID No.;2008, Seq. ID No. 2010, Seq. ID No. 2012, Seq. ID No. 2018, Seq. ID No. 2020, Seq. ID No. 2024, Seq. ID No. 2026, Seq. ID No. 2028, Seq. ID No. 2040, Seq. ID No. 2042, Seq. ID No. 2044, Seq. ID No. 2046, Seq. ID No. 2050, Seq. ID No. 2082, Seq. ID No. 2084, Seq. ID No. 2086, Seq. ID No. 2106, Seq. ID No. 2108, Seq. ID No. 2110, Seq. ID No. 2112, Seq. ID No. 2130, Seq. ID No. 2132, Seq. ID No. 2134, Seq. ID No. 2146, Seq. ID No. 2156, Seq. ID No. 2158, Seq. ID No. 2160, Seq. ID No. 2162, Seq. ID No. 2172, Seq. ID No. 2188, Seq. ID No. 2190, Seq. ID No. 2202, Seq. ID No. 2204, Seq. ID No. 2210, Seq. ID No. 2212, Seq. ID No. 2220, Seq. ID No. 2226, Seq. ID No. 2244, Seq. ID No. 2246, Seq. ID No. 2248, Seq. ID No. 2250, Seq. ID No. 2252, Seq. ID No. 2256, Seq. ID No. 2278, Seq. ID No. 2280, Seq. ID No. 2342, Seq. ID No. 2352, Seq. ID No. 2354, Seq. ID No. 2356, Seq. ID No. 2358, Seq. ID No. 2360, Seq. ID No. 2366, Seq. ID No. 2368, Seq. ID No. 2372, Seq. ID No. 2373, Seq. ID No. 2394, Seq. ID No. 2396, Seq. ID No. 2426, Seq. ID No. 2428, Seq. ID No. 2432, Seq. ID No. 2440, Seq. ID No. 2442, Seq. ID No. 2444, Seq. ID No. 2448, Seq. ID No. 2460, Seq. ID No. 2480, Seq. ID No. 2494, Seq. ID No. 2502, Seq. ID No. 2504, Seq. ID No. 2522, Seq. ID No. 2524, Seq. ID No. 2528, Seq. ID No. 2592, Seq. ID No. 2602, Seq. ID No. 2604, Seq. ID No. 2612, Seq. ID No. 2628, Seq. ID No. 2630, Seq. ID No. 2654, Seq. ID No. 2662, Seq. ID No. 2692, Seq. ID No. 2696, Seq. ID No. 2698, Seq. ID No. 2718, Seq. ID No. 2730, Seq. ID No. 2732, Seq. ID No. 2734, Seq. ID No. 2736, Seq. ID No. 2740, Seq. ID No. 2742, Seq. ID No. 2744, Seq. ID No. 2778, Seq. ID No. 2780, Seq. ID No. 2782, Seq. ID No. 2784, Seq. ID No. 2802, Seq. ID No. 2806, Seq. ID No. 2808, Seq. ID No. 2810, Seq. ID No. 2812, Seq. ID No. 2814, Seq. ID No. 2816, Seq. ID No. 2818, Seq. ID No. 2820, Seq. ID No. 2830, Seq. ID No. 2832, Seq. ID No. 2834, Seq. ID No. 2836, Seq. ID No. 2838, Seq. ID No. 2840, Seq. ID No. 2842, Seq. ID No. 2846, Seq. ID No. 2850, Seq. ID No. 2852, Seq. ID No. 2854, Seq. ID No. 2856, Seq. ID No. 2858, Seq. ID No. 2860, Seq. ID No. 2862, Seq. ID No. 2866, Seq. ID No. 2874, Seq. ID No. 2876, Seq. ID No. 2878, Seq. ID No. 2884, Seq. ID No. 2886, Seq. ID No. 2888, Seq. ID No. 2890, Seq. ID No. 2894, Seq. ID No. 2896, Seq. ID No. 2904, Seq. ID No. 2910, Seq. ID No. 2936, Seq. ID No. 2938, Seq. ID No. 2940, Seq. ID No. 2942, Seq. ID No. 2944, Seq. ID No. 2946, Seq. ID No. 2948, Seq. ID No. 2950, Seq. ID No. 2952, Seq. ID No. 2954, Seq. ID No. 2966, Seq. ID No. 2968, Seq. ID No. 2974, Seq. ID No. 2976, Seq. ID No. 2978, Seq. ID No. 2982, Seq. ID No. 2984, Seq. ID No. 2986, Seq. ID No. 2988, Seq. ID No. 2990, Seq. ID No. 2992, Seq. ID No. 3002, Seq. ID No. 3008, Seq. ID No. 3010, Seq. ID No. 3012, Seq. ID No. 3022, Seq. ID No. 3024, Seq. ID No. 3042, Seq. ID No. 3046, Seq. ID No. 3072, Seq. ID No. 3088, Seq. ID No. 3106, Seq. ID No. 3108, Seq. ID No. 3120, Seq. ID No. 3122, Seq. ID No. 3124, Seq. ID No. 3152, Seq. ID No. 3154, Seq. ID No. 3168, Seq. ID No. 3174, Seq. ID No. 3176, Seq. ID No. 3178, Seq. ID No. 3182, Seq. ID No. 3194, Seq. ID No. 3214, Seq. ID No. 3216, Seq. ID No. 3218, Seq. ID No. 3220, Seq. ID No. 3222, Seq. ID No. 3224, Seq. ID No. 3232, Seq. ID No. 3234, Seq. ID No. 3236, Seq. ID No. 3238, Seq. ID No. 3240, Seq. ID No. 3242, Seq. ID No. 3244, Seq. ID No. 3246, Seq. ID No. 3248, Seq. ID No. 3250, Seq. ID No. 3262, Seq. ID No. 3264, Seq. ID No. 3266, Seq. ID No. 3268, Seq. ID No. 3270, Seq. ID No. 3272, Seq. ID No. 3274, Seq. ID No. 3276, Seq. ID No. 3278, Seq. ID No. 3326, Seq. ID No. 3332, Seq. ID No. 3340, Seq. ID No. 3342, Seq. ID No. 3350, Seq. ID No. 3362, Seq. ID No. 3364, Seq. ID No. 3370, Seq. ID No. 3372, Seq. ID No. 3390, Seq. ID No. 3404, Seq. ID No. 3418, Seq. ID No. 3420, Seq. ID No. 3422, Seq. ID No. 3434, Seq. ID No. 3438, Seq. ID No. 3442, Seq. ID No. 3444, Seq. ID No. 3446, Seq. ID No. 3448, Seq. ID No. 3474, Seq. ID No. 3482, Seq. ID No. 3484, Seq. ID No. 3490, Seq. ID No. 3504, Seq. ID No. 3506, Seq. ID No. 3510, Seq. ID No. 3512, Seq. ID No. 3524, Seq. ID No. 3526, Seq. ID No. 3532, Seq. ID No. 3534, Seq. ID No. 3540, Seq. ID No. 3542, Seq. ID No. 3544, Seq. ID No. 3546, Seq. ID No. 3548, Seq. ID No. 3556, Seq. ID No. 3558, Seq. ID No. 3564, Seq. ID No. 3566, Seq. ID No. 3572, Seq. ID No. 3574, Seq. ID No. 3582, Seq. ID No. 3588, Seq. ID No. 3592, Seq. ID No. 3594, Seq. ID No. 3596, Seq. ID No. 3612, Seq. ID No. 3614, Seq. ID No. 3618, Seq. ID No. 3620, Seq. ID No. 3622, Seq. ID No. 3624, Seq. ID No. 3626, Seq. ID No. 3632, Seq. ID No. 3638, Seq. ID No. 3640, Seq. ID No. 3656, Seq. ID No. 3658, Seq. ID No. 3660, Seq. ID No. 3662, Seq. ID No. 3678, Seq. ID No. 3680, Seq. ID No. 3684, Seq. ID No. 3686, Seq. ID No. 3702, Seq. ID No. 3704, Seq. ID No. 3718, Seq. ID No. 3720, Seq. ID No. 3722, Seq. ID No. 3724, Seq. ID No. 3730, Seq. ID No. 3732, Seq. ID No. 3734, Seq. ID No. 3736, Seq. ID No. 3738, Seq. ID No. 3740, Seq. ID No. 3742, Seq. ID No. 3750, Seq. ID No. 3752, Seq. ID No. 3754, Seq. ID No. 3756, Seq. ID No. 3762, Seq. ID No. 3782, Seq. ID No. 3784, Seq. ID No. 3786, Seq. ID No. 3788, Seq. ID No. 3790, Seq. ID No. 3792, Seq. ID No. 3800, Seq. ID No. 3808, Seq. ID No. 3810, Seq. ID No. 3812, Seq. ID No. 3814, Seq. ID No. 3816, Seq. ID No. 3818, Seq. ID No. 3828, Seq. ID No. 3830, Seq. ID No. 3832, Seq. ID No. 3834, Seq. ID No. 3836, Seq. ID No. 3850, Seq. ID No. 3880, Seq. ID No. 3882, Seq. ID No. 3896, Seq. ID No. 3904, Seq. ID No. 3910, Seq. ID No. 3916, Seq. ID No. 3940, Seq. ID No. 3960, Seq. ID No. 3962, Seq. ID No. 3964, Seq. ID No. 3966, Seq. ID No. 3974, Seq. ID No. 3978, Seq. ID No. 3980, Seq. ID No. 3994, Seq. ID No. 3996, Seq. ID No. 3998, Seq. ID No. 4006, Seq. ID No. 4008, Seq. ID No. 4010, Seq. ID No. 4042, Seq. ID No. 4044, Seq. ID No. 4046, Seq. ID No. 4070, Seq. ID No. 4078, Seq. ID No. 4098, Seq. ID No. 4114, Seq. ID No. 4124, Seq. ID No. 4132, Seq. ID No. 4134, Seq. ID No. 4136, Seq. ID No. 4140, Seq. ID No. 4152, Seq. ID No. 4154, Seq. ID No. 4156, Seq. ID No. 4182, Seq. ID No. 4222, Seq. ID No. 4242, Seq. ID No. 4254, Seq. ID No. 4258, Seq. ID No. 4260, Seq. ID No. 4262, Seq. ID No. 4264, Seq. ID No. 4266, Seq. ID No. 4270, Seq. ID No. 4276, Seq. ID No. 4278, Seq. ID No. 4280, Seq. ID No. 4282, Seq. ID No. 4286, Seq. ID No. 4288, Seq. ID No. 4298, Seq. ID No. 4306, Seq. ID No. 4308, Seq. ID No. 4364, Seq. ID No. 4366, Seq. ID No. 4372, Seq. ID No. 4374, Seq. ID No. 4396, Seq. ID No. 4400, Seq. ID No. 4404, Seq. ID No. 4426, Seq. ID No. 4438, Seq. ID No. 4440, Seq. ID No. 4442, Seq. ID No. 4454, Seq. ID No. 4456, Seq. ID No. 4514, Seq. ID No. 4516, Seq. ID No. 4552, Seq. ID No. 4562, Seq. ID No. 4574, Seq. ID No. 4576, Seq. ID No. 4588, Seq. ID No. 4590, Seq. ID No. 4592, Seq. ID No. 4594, Seq. ID No. 4596, Seq. ID No. 4618, Seq. ID No. 4620, Seq. ID No. 4622, Seq. ID No. 4626, Seq. ID No. 4628, Seq. ID No. 4634, Seq. ID No. 4636, Seq. ID No. 4638, Seq. ID No. 4640, Seq. ID No. 4660, Seq. ID No. 4682, Seq. ID No. 4688, Seq. ID No. 4696, Seq. ID No. 4700, Seq. ID No. 4702, Seq. ID No. 4722, Seq. ID No. 4736, Seq. ID No. 4738, Seq. ID No. 4742, Seq. ID No. 4784, Seq. ID No. 4790, Seq. ID No. 4806, Seq. ID No. 4812, Seq. ID No. 4818, Seq. ID No. 4820, Seq. ID No. 4822, Seq. ID No. 4824, Seq. ID No. 4836, Seq. ID No. 4854, Seq. ID No. 4886, Seq. ID No. 4914, Seq. ID No. 4924, Seq. ID No. 4950, Seq. ID No. 4952, Seq. ID No. 4976, Seq. ID No. 4982, Seq. ID No. 4984, Seq. ID No. 4988, Seq. ID No. 4994, Seq. ID No. 5000, Seq. ID No. 5002, Seq. ID No. 5012, Seq. ID No. 5014, Seq. ID No. 5024, Seq. ID No. 5032, Seq. ID No. 5034, Seq. ID No. 5036, Seq. ID No. 5038, Seq. ID No. 5042, Seq. ID No. 5044, Seq. ID No. 5054, Seq. ID No. 5062, Seq. ID No. 5064, Seq. ID No. 5086, Seq. ID No. 5094, Seq. ID No. 5152, Seq. ID No. 5154, Seq. ID No. 5160, Seq. ID No. 5162, Seq. ID No. 5168, Seq. ID No. 5174, Seq. ID No. 5176, Seq. ID No. 5178, Seq. ID No. 5190, Seq. ID No. 5192, Seq. ID No. 5194, Seq. ID No. 5198, Seq. ID No. 5200, Seq. ID No. 5222, Seq. ID No. 5224, Seq. ID No. 5226, Seq. ID No. 5228, Seq. ID No. 5238, Seq. ID No. 5268, Seq. ID No. 5270, Seq. ID No. 5272, Seq. ID No. 5282, Seq. ID No. 5302, Seq. ID No. 5304, Seq. ID No. 5316, Seq. ID No. 5322, Seq. ID No. 5328, Seq. ID No. 5348, Seq. ID No. 5386, Seq. ID No. 5446, Seq. ID No. 5448, Seq. ID No. 5460, Seq. ID No. 5466, Seq. ID No. 5468, Seq. ID No. 5480, Seq. ID No. 5482, Seq. ID No. 5486, Seq. ID No. 5488, Seq. ID No. 5516, Seq. ID No. 5518, Seq. ID No. 5534, Seq. ID No. 5544, Seq. ID No. 5546, Seq. ID No. 5550, Seq. ID No. 5570, Seq. ID No. 5578, Seq. ID No. 5594, Seq. ID No. 5596, Seq. ID No. 5610, Seq. ID No. 5624, Seq. ID No. 5626, Seq. ID No. 5640, Seq. ID No. 5642, Seq. ID No. 5644, Seq. ID No. 5650, Seq. ID No. 5660, Seq. ID No. 5662, Seq. ID No. 5664, Seq. ID No. 5668, Seq. ID No. 5672, Seq. ID No. 5688, Seq. ID No. 5690, Seq. ID No. 5704, Seq. ID No. 5706, Seq. ID No. 5710, Seq. ID No. 5712, Seq. ID No. 5738, Seq. ID No. 5740, Seq. ID No. 5746, Seq. ID No. 5752, Seq. ID No. 5764, Seq. ID No. 5798, Seq. ID No. 5812, Seq. ID No. 5814, Seq. ID No. 5816, Seq. ID No. 5828, Seq. ID No. 5830, Seq. ID No. 5844, Seq. ID No. 5846, Seq. ID No. 5874, Seq. ID No. 5880, Seq. ID No. 5884, Seq. ID No. 5886, Seq. ID No. 5888, Seq. ID No. 5890, Seq. ID No. 5892, Seq. ID No. 5932, Seq. ID No. 5956, Seq. ID No. 5964, Seq. ID No. 5966, Seq. ID No. 5976, Seq. ID No. 5984, Seq. ID No. 5986, Seq. ID No. 5988, Seq. ID No. 5990, Seq. ID No. 6006, Seq. ID No. 6014, Seq. ID No. 6032, Seq. ID No. 6036, Seq. ID No. 6046, Seq. ID No. 6060, Seq. ID No. 6062, Seq. ID No. 6064, Seq. ID No. 6074, Seq. ID No. 6082, Seq. ID No. 6092, Seq. ID No. 6094, Seq. ID No. 6128, Seq. ID No. 6160, Seq. ID No. 6198, Seq. ID No. 6200, Seq. ID No. 6204, Seq. ID No. 6218, Seq. ID No. 6222, Seq. ID No. 6224, Seq. ID No. 6238, Seq. ID No. 6240, Seq. ID No. 6242, Seq. ID No. 6246, Seq. ID No. 6248, Seq. ID No. 6250, Seq. ID No. 6260, Seq. ID No. 6266, Seq. ID No. 6268, Seq. ID No. 6274, Seq. ID No. 6284, Seq. ID No. 6286, Seq. ID No. 6324, Seq. ID No. 6326, Seq. ID No. 6328, Seq. ID No. 6362, Seq. ID No. 6364, Seq. ID No. 6378, Seq. ID No. 6382, Seq. ID No. 6402, Seq. ID No. 6404, Seq. ID No. 6420, Seq. ID No. 6426, Seq. ID No. 6428, Seq. ID No. 6430, Seq. ID No. 6432, Seq. ID No. 6434, Seq. ID No. 6436, Seq. ID No. 6438, Seq. ID No. 6440, Seq. ID No. 6448, Seq. ID No. 6450, Seq. ID No. 6452, Seq. ID No. 6454, Seq. ID No. 6456, Seq. ID No. 6458, Seq. ID No. 6466, Seq. ID No. 6468, Seq. ID No. 6470, Seq. ID No. 6472, Seq. ID No. 6474, Seq. ID No. 6476, Seq. ID No. 6478, Seq. ID No. 6480, Seq. ID No. 6482, Seq. ID No. 6484, Seq. ID No. 6486, Seq. ID No. 6488, Seq. ID No. 6490, Seq. ID No. 6492, Seq. ID No. 6496, Seq. ID No. 6498, Seq. ID No. 6508, Seq. ID No. 6518, Seq. ID No. 6520, Seq. ID No. 6522, Seq. ID No. 6524, Seq. ID No. 6526, Seq. ID No. 6528, Seq. ID No. 6530, Seq. ID No. 6534, Seq. ID No. 6540, Seq. ID No. 6542, Seq. ID No. 6544, Seq. ID No. 6556, Seq. ID No. 6558, Seq. ID No. 6562, Seq. ID No. 6564, Seq. ID No. 6566, Seq. ID No. 6568, Seq. ID No. 6570, Seq. ID No. 6572, Seq. ID No. 6574, Seq. ID No. 6582, Seq. ID No. 6584, Seq. ID No. 6632, Seq. ID No. 6636, Seq. ID No. 6638, Seq. ID No. 6640, Seq. ID No. 6644, Seq. ID No. 6646, Seq. ID No. 6648, and Seq. ID No. 6650.

In yet another preferred embodiment, the polypeptide is selected from the Alloiococcus otitidis polypeptides identified by Glimmer™ ORF finder program, and is selected from one of Seq. ID No. 2, Seq. ID No. 6, Seq. ID No. 12, Seq. ID No. 14, Seq. ID No. 16, Seq. ID No. 18, Seq. ID No. 26, Seq. ID No. 28, Seq. ID No. 30, Seq. ID No. 36, Seq. ID No. 38, Seq. ID No. 42, Seq. ID No. 44, Seq. ID No. 48, Seq. ID No. 52, Seq. ID No. 54, Seq. ID No. 60, Seq. ID No. 64, Seq. ID No. 70, Seq. ID No. 74, Seq. ID No. 76, Seq. ID No. 82, Seq. ID No. 84, Seq. ID No. 90, Seq. ID No. 94, Seq. ID No. 98, Seq. ID No. 104, Seq. ID No. 112, Seq. ID No. 122, Seq. ID No. 126, Seq. ID No. 130, Seq. ID No. 136, Seq. ID No. 138, Seq. ID No. 146, Seq. ID No. 150, Seq. ID No. 158, Seq. ID No. 168, Seq. ID No. 174, Seq. ID No. 184, Seq. ID No. 188, Seq. ID No. 190, Seq. ID No. 192, Seq. ID No. 196, Seq. ID No. 198, Seq. ID No. 204, Seq. ID No. 208, Seq. ID No. 216, Seq. ID No. 220, Seq. ID No. 224, Seq. ID No. 226, Seq. ID No. 228, Seq. ID No. 232, Seq. ID No. 234, Seq. ID No. 240, Seq. ID No. 242, Seq. ID No. 248, Seq. ID No. 254, Seq. ID No. 262, Seq. ID No. 266, Seq. ID No. 270, Seq. ID No. 274, Seq. ID No. 276, Seq. ID No. 278, Seq. ID No. 284, Seq. ID No. 292, Seq. ID No. 294, Seq. ID No. 298, Seq. ID No. 302, Seq. ID No. 308, Seq. ID No. 310, Seq. ID No. 314, Seq. ID No. 318, Seq. ID No. 322, Seq. ID No. 326, Seq. ID No. 336, Seq. ID No. 344, Seq. ID No. 346, Seq. ID No. 354, Seq. ID No. 356, Seq. ID No. 362, Seq. ID No. 364, Seq. ID No. 368, Seq. ID No. 376, Seq. ID No. 380, Seq. ID No. 384, Seq. ID No. 390, Seq. ID No. 392, Seq. ID No. 398, Seq. ID No. 406, Seq. ID No. 412, Seq. ID No. 416, Seq. ID No. 418, Seq. ID No. 424, Seq. ID No. 426, Seq. ID No. 428, Seq. ID No. 430, Seq. ID No. 436, Seq. ID No. 438, Seq. ID No. 440, Seq. ID No. 442, Seq. ID No. 446, Seq. ID No. 448, Seq. ID No. 454, Seq. ID No. 462, Seq. ID No. 464, Seq. ID No. 472, Seq. ID No. 486, Seq. ID No. 502, Seq. ID No. 506, Seq. ID No. 512, Seq. ID No. 516, Seq. ID No. 518, Seq. ID No. 522, Seq. ID No. 524, Seq. ID No. 532, Seq. ID No. 534, Seq. ID No. 540, Seq. ID No. 542, Seq. ID No. 544, Seq. ID No. 552, Seq. ID No. 556, Seq. ID No. 562, Seq. ID No. 566, Seq. ID No. 570, Seq. ID No. 576, Seq. ID No. 580, Seq. ID No. 588, Seq. ID No. 594, Seq. ID No. 598, Seq. ID No. 604, Seq. ID No. 606, Seq. ID No. 610, Seq. ID No. 612, Seq. ID No. 614, Seq. ID No. 616, Seq. ID No. 624, Seq. ID No. 628, Seq. ID No. 630, Seq. ID No. 632, Seq. ID No. 636, Seq. ID No. 638, Seq. ID No. 648, Seq. ID No. 650, Seq. ID No. 662, Seq. ID No. 670, Seq. ID No. 674, Seq. ID No. 676, Seq. ID No. 682, Seq. ID No. 684, Seq. ID No. 690, Seq. ID No. 702, Seq. ID No. 704, Seq. ID No. 710, Seq. ID No. 714, Seq. ID No. 730, Seq. ID No. 734, Seq. ID No. 736, Seq. ID No. 738, Seq. ID No. 742, Seq. ID No. 748, Seq. ID No. 752, Seq. ID No. 754, Seq. ID No. 760, Seq. ID No. 766, Seq. ID No. 768, Seq. ID No. 772, Seq. ID No. 782, Seq. ID No. 784, Seq. ID No. 788, Seq. ID No. 792, Seq. ID No. 796, Seq. ID No. 800, Seq. ID No. 808, Seq. ID No. 818, Seq. ID No. 820, Seq. ID No. 824, Seq. ID No. 828, Seq. ID No. 832, Seq. ID No. 836, Seq. ID No. 838, Seq. ID No. 840, Seq. ID No. 848, Seq. ID No. 852, Seq. ID No. 856, Seq. ID No. 860, Seq. ID No. 868, Seq. ID No. 872, Seq. ID No. 876, Seq. ID No. 882, Seq. ID No. 886, Seq. ID No. 890, Seq. ID No. 892, Seq. ID No. 896, Seq. ID No. 902, Seq. ID No. 908, Seq. ID No. 916, Seq. ID No. 920, Seq. ID No. 926, Seq. ID No. 930, Seq. ID No. 936, Seq. ID No. 940, Seq. ID No. 950, Seq. ID No. 952, Seq. ID No. 956, Seq. ID No. 962, Seq. ID No. 966, Seq. ID No. 968, Seq. ID No. 972, Seq. ID No. 986, Seq. ID No. 994, Seq. ID No. 998, Seq. ID No. 1004, Seq. ID No. 1006, Seq. ID No. 1010, Seq. ID No. 1018, Seq. ID No. 1024, Seq. ID No. 1040, Seq. ID No. 1042, Seq. ID No. 1044, Seq. ID No. 1052, Seq. ID No. 1054, Seq. ID No. 1058, Seq. ID No. 1062, Seq. ID No. 1066, Seq. ID No. 1068, Seq. ID No. 1070, Seq. ID No. 1074, Seq. ID No. 1076, Seq. ID No. 1084, Seq. ID No. 1088, Seq. ID No. 1092, Seq. ID No. 1094, Seq. ID No. 1098, Seq. ID No. 1100, Seq. ID No. 1104, Seq. ID No. 1110, Seq. ID No. 1116, Seq. ID No. 1118, Seq. ID No. 1124, Seq. ID No. 1130, Seq. ID No. 1134, Seq. ID No. 1138, Seq. ID No. 1144, Seq. ID No. 1148, Seq. ID No. 1150, Seq. ID No. 1156, Seq. ID No. 1158, Seq. ID No. 1160, Seq. ID No. 1164, Seq. ID No. 1172, Seq. ID No. 1180, Seq. ID No. 1182, Seq. ID No. 1188, Seq. ID No. 1194, Seq. ID No. 1200, Seq. ID No. 1206, Seq. ID No. 1212, Seq. ID No. 1218, Seq. ID No. 1222, Seq. ID No. 1224, Seq. ID No. 1226, Seq. ID No. 1232, Seq. ID No. 1234, Seq. ID No. 1238, Seq. ID No. 1242, Seq. ID No. 1254, Seq. ID No. 1258, Seq. ID No. 1264, Seq. ID No. 1272, Seq. ID No. 1282, Seq. ID No. 1318, Seq. ID No. 1324, Seq. ID No. 1332, Seq. ID No. 1336, Seq. ID No. 1340, Seq. ID No. 1346, Seq. ID No. 1348, Seq. ID No. 1362, Seq. ID No. 1370, Seq. ID No. 1378, Seq. ID No. 1380, Seq. ID No. 1388, Seq. ID No. 1394, Seq. ID No. 1396, Seq. ID No. 1400, Seq. ID No. 1404, Seq. ID No. 1406, Seq. ID No. 1412, Seq. ID No. 1414, Seq. ID No. 1416, Seq. ID No. 1420, Seq. ID No. 1426, Seq. ID No. 1428, Seq. ID No. 1430, Seq. ID No. 1432, Seq. ID No. 1434, Seq. ID No. 1438, Seq. ID No. 1444, Seq. ID No. 1450, Seq. ID No. 1452, Seq. ID No. 1456, Seq. ID No. 1458, Seq. ID No. 1460, Seq. ID No. 1464, Seq. ID No. 1466, Seq. ID No. 1470, Seq. ID No. 1472, Seq. ID No. 1474, Seq. ID No. 1476, Seq. ID No. 1478, Seq. ID No. 1486, Seq. ID No. 1488, Seq. ID No. 1492, Seq. ID No. 1494, Seq. ID No. 1496, Seq. ID No. 1498, Seq. ID No. 1502, Seq. ID No. 1506, Seq. ID No. 1508, Seq. ID No. 1510, Seq. ID No. 1518, Seq. ID No. 1526, Seq. ID No. 1528, Seq. ID No. 1532, Seq. ID No. 1540, Seq. ID No. 1542, Seq. ID No. 1544, Seq. ID No. 1550, Seq. ID No. 1562, Seq. ID No. 1564, Seq. ID No. 1568, Seq. ID No. 1572, Seq. ID No. 1574, Seq. 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ID No. 2036, Seq. ID No. 2038, Seq. ID No. 2046, Seq. ID No. 2048, Seq. ID No. 2056, Seq. ID No. 2060, Seq. ID No. 2066, Seq. ID No. 2068, Seq. ID No. 2070, Seq. ID No. 2072, Seq. ID No. 2074, Seq. ID No. 2080, Seq. ID No. 2092, Seq. ID No. 2094, Seq. ID No. 2098, Seq. ID No. 2100, Seq. ID No. 2104, Seq. ID No. 2116, Seq. ID No. 2120, Seq. ID No. 2128, Seq. ID No. 2136, Seq. ID No. 2138, Seq. ID No. 2142, Seq. ID No. 2144, Seq. ID No. 2148, Seq. ID No. 2154, Seq. ID No. 2160, Seq. ID No. 2162, Seq. ID No. 2166, Seq. ID No. 2170, Seq. ID No. 2180, Seq. ID No. 2184, Seq. ID No. 2186, Seq. ID No. 2190, Seq. ID No. 2192, Seq. ID No. 2194, Seq. ID No. 2196, Seq. ID No. 2200, Seq. ID No. 2208, Seq. ID No. 2218, Seq. ID No. 2220, Seq. ID No. 2222, Seq. ID No. 2224, Seq. ID No. 2228, Seq. ID No. 2230, Seq. ID No. 2232, Seq. ID No. 2234, Seq. ID No. 2242, Seq. ID No. 2246, Seq. ID No. 2252, Seq. ID No. 2254, Seq. ID No. 2258, Seq. ID No. 2260, Seq. ID No. 2264, Seq. ID No. 2268, Seq. 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ID No. 3000, Seq. ID No. 3002, Seq. ID No. 3006, Seq. ID No. 3012, Seq. ID No. 3020, Seq. ID No. 3028, Seq. ID No. 3034, Seq. ID No. 3036, Seq. ID No. 3040, Seq. ID No. 3044, Seq. ID No. 3046, Seq. ID No. 3050, Seq. ID No. 3056, Seq. ID No. 3060, Seq. ID No. 3062, Seq. ID No. 3068, Seq. ID No. 3070, Seq. ID No. 3082, Seq. ID No. 3090, Seq. ID No. 3092, Seq. ID No. 3094, Seq. ID No. 3098, Seq. ID No. 3104, Seq. ID No. 3108, Seq. ID No. 3112, Seq. ID No. 3118, Seq. ID No. 3126, Seq. ID No. 3134, Seq. ID No. 3136, Seq. ID No. 3138, Seq. ID No. 3142, Seq. ID No. 3144, Seq. ID No. 3150, Seq. ID No. 3156, Seq. ID No. 3158, Seq. ID No. 3160, Seq. ID No. 3162, Seq. ID No. 3166, Seq. ID No. 3172, Seq. ID No. 3178, Seq. ID No. 3180, Seq. ID No. 3184, Seq. ID No. 3186, Seq. ID No. 3190, Seq. ID No. 3192, Seq. ID No. 3198, Seq. ID No. 3204, Seq. ID No. 3206, Seq. ID No. 3212, Seq. ID No. 3218, Seq. ID No. 3222, Seq. ID No. 3228, Seq. ID No. 3230, Seq. ID No. 3234, Seq. ID No. 3236, Seq. ID No. 3240, Seq. ID No. 3250, Seq. ID No. 3252, Seq. ID No. 3254, Seq. ID No. 3258, Seq. ID No. 3260, Seq. ID No. 3264, Seq. ID No. 3266, Seq. ID No. 3272, Seq. ID No. 3274, Seq. ID No. 3278, Seq. ID No. 3284, Seq. ID No. 3286, Seq. ID No. 3288, Seq. ID No. 3290, Seq. ID No. 3294, Seq. ID No. 3296, Seq. ID No. 3300, Seq. ID No. 3304, Seq. ID No. 3308, Seq. ID No. 3314, Seq. ID No. 3316, Seq. ID No. 3320, Seq. ID No. 3324, Seq. ID No. 3330, Seq. ID No. 3336, Seq. ID No. 3338, Seq. ID No. 3348, Seq. ID No. 3356, Seq. ID No. 3360, Seq. ID No. 3364, Seq. ID No. 3368, Seq. ID No. 3378, Seq. ID No. 3380, Seq. ID No. 3384, Seq. ID No. 3388, Seq. ID No. 3400, Seq. ID No. 3402, Seq. ID No. 3404, Seq. ID No. 3410, Seq. ID No. 3414, Seq. ID No. 3416, Seq. ID No. 3418, Seq. ID No. 3426, Seq. ID No. 3428, Seq. ID No. 3432, Seq. ID No. 3436, Seq. ID No. 3438, Seq. ID No. 3440, Seq. ID No. 3448, Seq. ID No. 3460, Seq. ID No. 3462, Seq. ID No. 3468, Seq. ID No. 3470, Seq. ID No. 3472, Seq. ID No. 3474, Seq. ID No. 3476, Seq. ID No. 3480, Seq. ID No. 3484, Seq. ID No. 3486, Seq. ID No. 3488, Seq. ID No. 3496, Seq. ID No. 3502, Seq. ID No. 3506, Seq. ID-No. 3508, Seq. ID No. 3510, Seq. ID No. 3512, Seq. ID No. 3520, Seq. ID No. 3522, Seq. ID No. 3526, Seq. ID No. 3530, Seq. ID No. 3534, Seq. ID No. 3538, Seq. ID No. 3544, Seq. ID No. 3550, Seq. ID No. 3554, Seq. ID No. 3562, Seq. ID No. 3566, Seq. ID No. 3570, Seq. ID No. 3576, Seq. ID No. 3580, Seq. ID No. 3584, Seq. ID No. 3586, Seq. ID No. 3590, Seq. ID No. 3600, Seq. ID No. 3606, Seq. ID No. 3608, Seq. ID No. 3610, Seq. ID No. 3612, Seq. ID No. 3616, Seq. ID No. 3620, Seq. ID No. 3630, Seq. ID No. 3636, Seq. ID No. 3640, Seq. ID No. 3642, Seq. ID No. 3644, Seq. ID No. 3646, Seq. ID No. 3652, Seq. ID No. 3654, Seq. ID No. 3660, Seq. ID No. 3664, Seq. ID No. 3666, Seq. ID No. 3668, Seq. ID No. 3670, Seq. ID No. 3676, Seq. ID No. 3682, Seq. ID No. 3690, Seq. ID No. 3696, Seq. ID No. 3700, Seq. ID No. 3710, Seq. 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ID No. 3956, Seq. ID No. 3958, Seq. ID No. 3972, Seq. ID No. 3976, Seq. ID No. 3984, Seq. ID No. 3986, Seq. ID No. 3988, Seq. ID No. 3992, Seq. ID No. 4004, Seq. ID No. 4010, Seq. ID No. 4014, Seq. ID No. 4016, Seq. ID No. 4018, Seq. ID No. 4022, Seq. ID No. 4024, Seq. ID No. 4030, Seq. ID No. 4032, Seq. ID No. 4036, Seq. ID No. 4038, Seq. ID No. 4040, Seq. ID No. 4050, Seq. ID No. 4056, Seq. ID No. 4058, Seq. ID No. 4062, Seq. ID No. 4064, Seq. ID No. 4068, Seq. ID No. 4070, Seq. ID No. 4076, Seq. ID No. 4078, Seq. ID No. 4080, Seq. ID No. 4088, Seq. ID No. 4090, Seq. ID No. 4096, Seq. ID No. 4098, Seq. ID No. 4100, Seq. ID No. 4106, Seq. ID No. 4112, Seq. ID No. 4118, Seq. ID No. 4122, Seq. ID No. 4124, Seq. ID No. 4128, Seq. ID No. 4130, Seq. ID No. 4134, Seq. ID No. 4138, Seq. ID No. 4146, Seq. ID No. 4150, Seq. ID No. 4158, Seq. ID No. 4162, Seq. ID No. 4164, Seq. ID No. 4168, Seq. ID No. 4174, Seq. ID No. 4180, Seq. ID-No. 4186, Seq. ID No. 4192, Seq. ID No. 4194, Seq. ID No. 4196, Seq. ID No. 4198, Seq. ID No. 4200, Seq. ID No. 4202, Seq. ID No. 4204, Seq. ID No. 4206, Seq. ID No. 4212, Seq. ID No. 4216, Seq. ID No. 4218, Seq. ID No. 4220, Seq. ID No. 4236, Seq. ID No. 4238, Seq. ID No. 4240, Seq. ID No. 4244, Seq. ID No. 4252, Seq. ID No. 4256, Seq. ID No. 4264, Seq. ID No. 4268, Seq. ID No. 4272, Seq. ID No. 4274, Seq. ID No. 4280, Seq. ID No. 4282, Seq. ID No. 4284, Seq. ID No. 4292, Seq. ID No. 4296, Seq. ID No. 4300, Seq. ID No. 4302, Seq. ID No. 4304, Seq. ID No. 4308, Seq. ID No. 4310, Seq. ID No. 4314, Seq. ID No. 4318, Seq. ID No. 4324, Seq. ID No. 4326, Seq. ID No. 4330, Seq. ID No. 4332, Seq. ID No. 4334, Seq. ID No. 4340, Seq. ID No. 4344, Seq. ID No. 4348, Seq. ID No. 4354, Seq. ID No. 4356, Seq. ID No. 4358, Seq. ID No. 4366, Seq. ID No. 4370, Seq. ID No. 4374, Seq. ID No. 4376, Seq. ID No. 4378, Seq. ID No. 4380, Seq. ID No. 4382, Seq. ID No. 4384, Seq. ID No. 4392, Seq. ID No. 4394, Seq. ID No. 4398, Seq. ID No. 4402, Seq. ID No. 4412, Seq. ID No. 4418, Seq. ID No. 4424, Seq. ID No. 4432, Seq. ID No. 4434, Seq. ID No. 4436, Seq. ID No. 4444, Seq. ID No. 4448, Seq. ID No. 4452, Seq. ID No. 4460, Seq. ID No. 4462, Seq. ID No. 4468, Seq. ID No. 4472, Seq. ID No. 4476, Seq. ID No. 4480, Seq. ID No. 4482, Seq. ID No. 4488, Seq. ID No. 4492, Seq. ID No. 4502, Seq. ID No. 4506, Seq. ID No. 4512, Seq. ID No. 4524, Seq. ID No. 4532, Seq. ID No. 4534, Seq. ID No. 4538, Seq. ID No. 4540, Seq. ID No. 4542, Seq. ID No. 4544, Seq. ID No. 4548, Seq. ID No. 4550, Seq. ID No. 4560, Seq. ID No. 4566, Seq. ID No. 4568, Seq. ID No. 4572, Seq. ID No. 4576, Seq. ID No. 4578, Seq. ID No. 4582, Seq. ID No. 4586, Seq. ID No. 4592, Seq. ID No. 4596, Seq. ID No. 4598, Seq. ID No. 4604, Seq. ID No. 4608, Seq. ID No. 4610, Seq. ID No. 4612, Seq. ID No. 4616, Seq. ID No. 4624, Seq. ID No. 4628, Seq. ID No. 4632, Seq. ID No. 4636, Seq. ID No. 4638, Seq. ID No. 4644, Seq. ID No. 4650, Seq. ID No. 4652, Seq. ID No. 4654, Seq. ID No. 4658, Seq. ID No. 4662, Seq. ID No. 4664, Seq. ID No. 4670, Seq. ID No. 4672, Seq. ID No. 4674, Seq. ID No. 4680, Seq. ID No. 4686, Seq. ID No. 4694, Seq. ID No. 4698, Seq. ID No. 4704, Seq. ID No. 4706, Seq. ID No. 4714, Seq. ID No. 4718, Seq. ID No. 4720, Seq. ID No. 4726, Seq. ID No. 4730, Seq. ID No. 4732, Seq. ID No. 4734, Seq. ID No. 4740, Seq. ID No. 4744, Seq. ID No. 4746, Seq. ID No. 4748, Seq. ID No. 4750, Seq. ID No. 4752, Seq. ID No. 4758, Seq. ID No. 4766, Seq. ID No. 4770, Seq. ID No. 4778, Seq. ID No. 4780, Seq. ID No. 4782, Seq. ID No. 4788, Seq. ID No. 4790, Seq. ID No. 4792, Seq. ID No. 4798, Seq. ID No. 4804, Seq. ID No. 4808, Seq. ID No. 4810, Seq. ID No. 4812, Seq. ID No. 4814, Seq. ID No. 4816, Seq. ID No. 4822, Seq. ID No. 4824, Seq. ID No. 4826, Seq. ID No. 4828, Seq. ID No. 4834, Seq. ID No. 4836, Seq. ID No. 4838, Seq. ID No. 4844, Seq. ID No. 4846, Seq. ID No. 4848, Seq. ID No. 4850, Seq. ID No. 4860, Seq. ID No. 4862, Seq. ID No. 4866, Seq. ID No. 4868, Seq. ID No. 4876, Seq. ID No. 4878, Seq. ID No. 4880, Seq. ID No. 4882, Seq. ID No. 4884, Seq. ID No. 4886, Seq. ID No. 4888, Seq. ID No. 4894, Seq. ID No. 4900, Seq. ID No. 4902, Seq. ID No. 4904, Seq. ID No. 4906, Seq. ID No. 4908, Seq. ID No. 4912, Seq. ID No. 4916, Seq. ID No. 4918, Seq. ID No. 4920, Seq. ID No. 4922, Seq. ID No. 4928, Seq. ID No. 4932, Seq. ID No. 4936, Seq. ID No. 4940, Seq. ID No. 4942, Seq. ID No. 4944, Seq. ID No. 4946, Seq. ID No. 4948, Seq. ID No. 4954, Seq. ID No. 4958, Seq. ID No. 4960, Seq. ID No. 4964, Seq. ID No. 4966, Seq. ID No. 4970, Seq. ID No. 4972, Seq. ID No. 4974, Seq. ID No. 4980, Seq. ID No. 4986, Seq. ID No. 4990, Seq. ID No. 4992, Seq. ID No. 4996, Seq. ID No. 4998, Seq. ID No. 5002, Seq. ID No. 5008, Seq. ID No. 5010, Seq. ID No. 5018, Seq. ID No. 5022, Seq. ID No. 5028, Seq. ID No. 5030, Seq. ID No. 5040, Seq. ID No. 5048, Seq. ID No. 5052, Seq. ID No. 5054, Seq. ID No. 5056, Seq. ID No. 5060, Seq. ID No. 5062, Seq. ID No. 5070, Seq. ID No. 5078, Seq. ID No. 5080, Seq. ID No. 5082, Seq. ID No. 5084, Seq. ID No. 5088, Seq. ID No. 5092, Seq. ID No. 5094, Seq. ID No. 5098, Seq. ID No. 5104, Seq. ID No. 5106, Seq. ID No. 5110, Seq. ID No. 5112, Seq. ID No. 5114, Seq. ID No. 5116, Seq. ID No. 5118, Seq. ID No. 5128, Seq. ID No. 5142, Seq. ID No. 5146, Seq. ID No. 5150, Seq. ID No. 5154, Seq. ID No. 5158, Seq. ID No. 5166, Seq. ID No. 5170, Seq. ID No. 5172, Seq. ID No. 5178, Seq. ID No. 5184, Seq. ID No. 5186, Seq. ID No. 5188, Seq. ID No. 5194, Seq. ID No. 5196, Seq. ID No. 5202, Seq. ID No. 5204, Seq. ID No. 5206, Seq. ID No. 5210, Seq. ID No. 5212, Seq. ID No. 5216, Seq. ID No. 5220, Seq. ID No. 5228, Seq. ID No. 5232, Seq. ID No. 5236, Seq. ID No. 5238, Seq. ID No. 5240, Seq. ID No. 5244, Seq. ID No. 5246, Seq. ID No. 5248, Seq. ID No. 5254, Seq. ID No. 5256, Seq. ID No. 5258, Seq. ID No. 5262, Seq. ID No. 5264, Seq. ID No. 5272, Seq. ID No. 5276, Seq. ID No. 5284, Seq. ID No. 5292, Seq. ID No. 5300, Seq. ID No. 5306, Seq. ID No. 5310, Seq. ID No. 5312, Seq. ID No. 5314, Seq. ID No. 5320, Seq. ID No. 5324, Seq. ID No. 5326, Seq. ID No. 5336, Seq. ID No. 5338, Seq. ID No. 5342, Seq. ID No. 5346, Seq. ID No. 5352, Seq. ID No. 5356, Seq. ID No. 5364, Seq. ID No. 5366, Seq. ID No. 5368, Seq. ID No. 5372, Seq. ID No. 5374, Seq. ID No. 5382, Seq. ID No. 5384, Seq. ID No. 5388, Seq. ID No. 5390, Seq. ID No. 5392, Seq. ID No. 5394, Seq. ID No. 5396, Seq. ID No. 5398, Seq. ID No. 5400, Seq. ID No. 5402, Seq. ID No. 5404, Seq. ID No. 5410, Seq. ID No. 5412, Seq. ID No. 5416, Seq. ID No. 5418, Seq. ID No. 5420, Seq. ID No. 5422, Seq. ID No. 5424, Seq. ID No. 5428, Seq. ID No. 5432, Seq. ID No. 5434, Seq. ID No. 5440, Seq. ID No. 5442, Seq. ID No. 5444, Seq. ID No. 5448, Seq. ID No. 5450, Seq. ID No. 5452, Seq. ID No. 5454, Seq. ID No. 5456, Seq. ID No. 5458, Seq. ID No. 5474, Seq. ID No. 5478, Seq. ID No. 5484, Seq. ID No. 5488, Seq. ID No. 5492, Seq. ID No. 5496, Seq. ID No. 5500, Seq. ID No. 5504, Seq. ID No. 5508, Seq. ID No. 5510, Seq. ID No. 5514, Seq. ID No. 5528, Seq. ID No. 5532, Seq. ID No. 5538, Seq. ID No. 5540, Seq. ID No. 5542, Seq. ID No. 5548, Seq. ID No. 5554, Seq. ID No. 5558, Seq. ID No. 5560, Seq. ID No. 5564, Seq. ID No. 5568, Seq. ID No. 5572, Seq. ID No. 5576, Seq. ID No. 5582, Seq. ID No. 5586, Seq. ID No. 5592, Seq. ID No. 5600, Seq. ID No. 5602, Seq. ID No. 5606, Seq. ID No. 5616, Seq. ID No. 5622, Seq. ID No. 5630, Seq. ID No. 5632, Seq. ID No. 5638, Seq. ID No. 5648, Seq. ID No. 5652, Seq. ID No. 5656, Seq. ID No. 5658, Seq. ID No. 5662, Seq. ID No. 5666, Seq. ID No. 5670, Seq. ID No. 5672, Seq. ID No. 5674, Seq. ID No. 5680, Seq. ID No. 5686, Seq. ID No. 5694, Seq. ID No. 5698, Seq. ID No. 5700, Seq. ID No. 5702, Seq. ID No. 5708, Seq. ID No. 5716, Seq. ID No. 5718, Seq. ID No. 5724, Seq. ID No. 5728, Seq. ID No. 5736, Seq. ID No. 5740, Seq. ID No. 5750, Seq. ID No. 5752, Seq. ID No. 5756, Seq. ID No. 5762, Seq. ID No. 5772, Seq. ID No. 5776, Seq. ID No. 5778, Seq. ID No. 5780, Seq. ID No. 5784, Seq. ID No. 5790, Seq. ID No. 5796, Seq. ID No. 5802, Seq. ID No. 5804, Seq. ID No. 5810, Seq. ID No. 5816, Seq. ID No. 5820, Seq. ID No. 5826, Seq. ID No. 5834, Seq. ID No. 5836, Seq. ID No. 5842, Seq. ID No. 5846, Seq. ID No. 5848, Seq. ID No. 5850, Seq. ID No. 5852, Seq. ID No. 5854, Seq. ID No. 5856, Seq. ID No. 5860, Seq. ID No. 5866, Seq. ID No. 5872, Seq. ID No. 5876, Seq. ID No. 5878, Seq. ID No. 5882, Seq. ID No. 5888, Seq. ID No. 5892, Seq. ID No. 5896, Seq. ID No. 5898, Seq. ID No. 5902, Seq. ID No. 5904, Seq. ID No. 5912, Seq. ID No. 5914, Seq. ID No. 5916, Seq. ID No. 5918, Seq. ID No. 5920, Seq. ID No. 5930, Seq. ID No. 5932, Seq. ID No. 5934, Seq. ID No. 5938, Seq. ID No. 5942, Seq. ID No. 5944, Seq. ID No. 5948, Seq. ID No. 5952, Seq. ID No. 5954, Seq. ID No. 5956, Seq. ID No. 5958, Seq. ID No. 5962, Seq. ID No. 5970, Seq. ID No. 5974, Seq. ID No. 5980, Seq. ID No. 5982, Seq. ID No. 5986, Seq. ID No. 5990, Seq. ID No. 5994, Seq. ID No. 6002, Seq. ID No. 6004, Seq. ID No. 6012, Seq. ID No. 6016, Seq. ID No. 6018, Seq. ID No. 6022, Seq. ID No. 6028, Seq. ID No. 6030, Seq. ID No. 6034, Seq. ID No. 6036, Seq. ID No. 6042, Seq. ID No. 6044, Seq. ID No. 6054, Seq. ID No. 6058, Seq. ID No. 6066, Seq. ID No. 6072, Seq. ID No. 6080, Seq. ID No. 6086, Seq. ID No. 6090, Seq. ID No. 6096, Seq. ID No. 6098, Seq. ID No. 6102, Seq. ID No. 6104, Seq. ID No. 6112, Seq. ID No. 6114, Seq. ID No. 6118, Seq. ID No. 6124, Seq. ID No. 6126, Seq. ID No. 6130, Seq. ID No. 6132, Seq. ID No. 6134, Seq. ID No. 6142, Seq. ID No. 6146, Seq. ID No. 6150, Seq. ID No. 6158, Seq. ID No. 6166, Seq. ID No. 6170, Seq. ID No. 6172, Seq. ID No. 6176, Seq. ID No. 6178, Seq. ID No. 6182, Seq. ID No. 6188, Seq. ID No. 6196, Seq. ID No. 6202, Seq. ID No. 6210, Seq. ID No. 6214, Seq. ID No. 6216, Seq. ID No. 6220, Seq. ID No. 6234, Seq. ID No. 6236, Seq. ID No. 6244, Seq. ID No. 6250, Seq. ID No. 6252, Seq. ID No. 6258, Seq. ID No. 6262, Seq. ID No. 6264, Seq. ID No. 6272, Seq. ID No. 6276, Seq. ID No. 6278, Seq. ID No. 6282, Seq. ID No. 6288, Seq. ID No. 6298, Seq. ID No. 6300, Seq. ID No. 6306, Seq. ID No. 6312, Seq. ID No. 6316, Seq. ID No. 6322, Seq. ID No. 6324, Seq. ID No. 6328, Seq. ID No. 6332, Seq. ID No. 6334, Seq. ID No. 6338, Seq. ID No. 6340, Seq. ID No. 6342, Seq. ID No. 6344, Seq. ID No. 6346, Seq. ID No. 6354, Seq. ID No. 6358, Seq. ID No. 6360, Seq. ID No. 6362, Seq. ID No. 6368, Seq. ID No. 6370, Seq. ID No. 6374, Seq. ID No. 6376, Seq. ID No. 6378, Seq. ID No. 6380, Seq. ID No. 6390, Seq. ID No. 6396, Seq. ID No. 6400, Seq. ID No. 6404, Seq. ID No. 6408, Seq. ID No. 6412, Seq. ID No. 6414, Seq. ID No. 6418, Seq. ID No. 6424, Seq. ID No. 6434, Seq. ID No. 6438, Seq. ID No. 6440, Seq. ID No. 6446, Seq. ID No. 6450, Seq. ID No. 6452, Seq. ID No. 6458, Seq. ID No. 6460, Seq. ID No. 6462, Seq. ID No. 6464, Seq. ID No. 6478, Seq. ID No. 6482, Seq. ID No. 6484, Seq. ID No. 6488, Seq. ID No. 6490, Seq. ID No. 6492, Seq. ID No. 6494, Seq. ID No. 6496, Seq. ID No. 6504, Seq. ID No. 6506, Seq. ID No. 6512, Seq. ID No. 6516, Seq. ID No. 6520, Seq. ID No. 6524, Seq. ID No. 6526, Seq. ID No. 6530, Seq. ID No. 6532, Seq. ID No. 6534, Seq. ID No. 6538, Seq. ID No. 6546, Seq. ID No. 6552, Seq. ID No. 6554, Seq. ID No. 6560, Seq. ID No. 6564, Seq. ID No. 6568, Seq. ID No. 6578, Seq. ID No. 6580, Seq. ID No. 6584, Seq. ID No. 6586, Seq. ID No. 6588, Seq. ID No. 6590, Seq. ID No. 6604, Seq. ID No. 6606, Seq. ID No. 6610, Seq. ID No. 6614, Seq. ID No. 6616, Seq. ID No. 6618, Seq. ID No. 6622, Seq. ID No. 6624, Seq. ID No. 6628, Seq. ID No. 6630, Seq. ID No. 6634, and Seq. ID No. 6640.

In yet another preferred embodiment, the polypeptide is selected from the Alloiococcus otitidis polypeptides identified by GeneMark™ ORF finder program, and is selected from one of Seq. ID No. 2, Seq. ID No. 4, Seq. ID No. 12, Seq. ID No. 14, Seq. ID No. 16, Seq. ID No. 18, Seq. ID No. 26, Seq. ID No. 28, Seq. ID No. 30, Seq. ID No. 36, Seq. ID No. 38, Seq. ID No. 40, Seq. ID No. 42, Seq. ID No. 44, Seq. ID No. 46, Seq. ID No. 50, Seq. ID No. 54, Seq. ID No. 58, Seq. ID No. 62, Seq. ID No. 70, Seq. ID No. 72, Seq. ID No. 76, Seq. ID No. 82, Seq. ID No. 84, Seq. ID No. 90, Seq. ID No. 96, Seq. ID No. 102, Seq. ID No. 112, Seq. ID No. 120, Seq. ID No. 126, Seq. ID No. 130, Seq. ID No. 136, Seq. ID No. 138, Seq. ID No. 142, Seq. ID No. 148, Seq. ID No. 152, Seq. ID No. 156, Seq. ID No. 168, Seq. ID No. 172, Seq. ID No. 182, Seq. ID No. 186, Seq. ID No. 188, Seq. ID No. 190, Seq. ID No. 192, Seq. ID No. 196, Seq. ID No. 200, Seq. ID No. 208, Seq. ID No. 214, Seq. ID No. 220, Seq. ID No. 222, Seq. ID No. 226, Seq. ID No. 228, Seq. ID No. 230, Seq. ID No. 234, Seq. ID No. 240, Seq. ID No. 242, Seq. ID No. 244, Seq. ID No. 254, Seq. ID No. 262, Seq. ID No. 264, Seq. ID No. 268, Seq. ID No. 274, Seq. ID No. 276, Seq. ID No. 278, Seq. ID No. 280, Seq. ID No. 292, Seq. ID No. 294, Seq. ID No. 296, Seq. ID No. 300, Seq. ID No. 304, Seq. ID No. 310, Seq. ID No. 312, Seq. ID No. 316, Seq. ID No. 320, Seq. ID No. 324, Seq. ID No. 332, Seq. ID No. 342, Seq. ID No. 346, Seq. ID No. 352, Seq. ID No. 356, Seq. ID No. 362, Seq. ID No. 364, Seq. ID No. 366, Seq. ID No. 376, Seq. ID No. 380, Seq. ID No. 382, Seq. ID No. 384, Seq. ID No. 390, Seq. ID No. 392, Seq. ID No. 396, Seq. ID No. 400, Seq. ID No. 406, Seq. ID No. 410, Seq. ID No. 414, Seq. ID No. 418, Seq. ID No. 422, Seq. ID No. 424, Seq. ID No. 426, Seq. ID No. 428, Seq. ID No. 430, Seq. ID No. 436, Seq. ID No. 438, Seq. ID No. 440, Seq. ID No. 442, Seq. ID No. 444, Seq. ID No. 446, Seq. ID No. 448, Seq. ID No. 450, Seq. ID No. 460, Seq. ID No. 466, Seq. ID No. 486, Seq. ID No. 502, Seq. ID No. 506, Seq. ID No. 512, Seq. ID No. 514, Seq. ID No. 518, Seq. ID No. 520, Seq. ID No. 524, Seq. ID No. 530, Seq. ID No. 534, Seq. ID No. 536, Seq. ID No. 542, Seq. ID No. 544, Seq. ID No. 552, Seq. ID No. 554, Seq. ID No. 560, Seq. ID No. 564, Seq. ID No. 570, Seq. ID No. 576, Seq. ID No. 580, Seq. ID No. 584, Seq. ID No. 592, Seq. ID No. 596, Seq. ID No. 602, Seq. ID No. 606, Seq. ID No. 608, Seq. ID No. 612, Seq. ID No. 614, Seq. ID No. 616, Seq. ID No. 622, Seq. ID No. 628, Seq. ID No. 630, Seq. ID No. 634, Seq. ID No. 636, Seq. ID No. 638, Seq. ID No. 644, Seq. ID No. 650, Seq. ID No. 652, Seq. ID No. 656, Seq. ID No. 658, Seq. ID No. 670, Seq. ID No. 672, Seq. ID No. 676, Seq. ID No. 682, Seq. ID No. 684, Seq. ID No. 686, Seq. ID No. 694, Seq. ID No. 704, Seq. ID No. 706, Seq. ID No. 712, Seq. ID No. 726, Seq. ID No. 732, Seq. ID No. 736, Seq. ID No. 738, Seq. ID No. 742, Seq. ID No. 744, Seq. ID No. 750, Seq. ID No. 754, Seq. ID No. 760, Seq. ID No. 774, Seq. ID No. 782, Seq. ID No. 784, Seq. ID No. 786, Seq. ID No. 790, Seq. ID No. 794, Seq. ID No. 798, Seq. ID No. 804, Seq. ID No. 816, Seq. ID No. 820, Seq. ID No. 822, Seq. ID No. 828, Seq. ID No. 832, Seq. ID No. 834, Seq. ID No. 836, Seq. ID No. 838, Seq. ID No. 842, Seq. ID No. 844, Seq. ID No. 850, Seq. ID No. 852, Seq. ID No. 854, Seq. ID No. 858, Seq. ID No. 866, Seq. ID No. 870, Seq. ID No. 874, Seq. ID No. 878, Seq. ID No. 884, Seq. ID No. 888, Seq. ID No. 892, Seq. ID No. 896, Seq. ID No. 902, Seq. ID No. 908, Seq. ID No. 912, Seq. ID No. 918, Seq. ID No. 922, Seq. ID No. 928, Seq. ID No. 936, Seq. ID No. 940, Seq. ID No. 946, Seq. ID No. 952, Seq. ID No. 954, Seq. ID No. 960, Seq. ID No. 964, Seq. ID No. 968, Seq. ID No. 970, Seq. ID No. 978, Seq. ID No. 990, Seq. ID No. 996, Seq. ID No. 1000, Seq. ID No. 1006, Seq. ID No. 1008, Seq. ID No. 1016, Seq. ID No. 1022, Seq. ID No. 1036, Seq. ID No. 1042, Seq. ID No. 1044, Seq. ID No. 1050, Seq. ID No. 1054, Seq. ID No. 1058, Seq. ID No. 1060, Seq. ID No. 1064, Seq. ID No. 1068, Seq. ID No. 1070, Seq. ID No. 1072, Seq. ID No. 1076, Seq. ID No. 1084, Seq. ID No. 1086, Seq. ID No. 1090, Seq. ID No. 1094, Seq. ID No. 1098, Seq. ID No. 1100, Seq. ID No. 1102, Seq. ID No. 1110, Seq. ID No. 1114, Seq. ID No. 1118, Seq. ID No. 1122, Seq. ID No. 1130, Seq. ID No. 1134, Seq. ID No. 1138, Seq. ID No. 1142, Seq. ID No. 1146, Seq. ID No. 1150, Seq. ID No. 1156, Seq. ID No. 1158, Seq. ID No. 1160, Seq. ID No. 1164, Seq. ID No. 1172, Seq. ID No. 1174, Seq. ID No. 1176, Seq. ID No. 1182, Seq. ID No. 1186, Seq. ID No. 1190, Seq. ID No. 1200, Seq. ID No. 1206, Seq. ID No. 1210, Seq. ID No. 1216, Seq. ID No. 1220, Seq. ID No. 1224, Seq. ID No. 1226, Seq. ID No. 1234, Seq. ID No. 1236, Seq. ID No. 1242, Seq. ID No. 1252, Seq. ID No. 1256, Seq. ID No. 1262, Seq. ID No. 1272, Seq. ID No. 1282, Seq. ID No. 1316, Seq. ID No. 1324, Seq. ID No. 1332, Seq. ID No. 1334, Seq. ID No. 1340, Seq. ID No. 1346, Seq. ID No. 1348, Seq. ID No. 1356, Seq. ID No. 1358, Seq. ID No. 1370, Seq. ID No. 1374, Seq. ID No. 1388, Seq. ID No. 1392, Seq. ID No. 1396, Seq. ID No. 1398, Seq. ID No. 1404, Seq. ID No. 1406, Seq. ID No. 1408, Seq. ID No. 1414, Seq. ID No. 1416, Seq. ID No. 1418, Seq. ID No. 1426, Seq. ID No. 1428, Seq. ID No. 1430, Seq. ID No. 1432, Seq. ID No. 1434, Seq. ID No. 1436, Seq. ID No. 1440, Seq. ID No. 1442, Seq. ID No. 1452, Seq. ID No. 1454, Seq. ID No. 1460, Seq. ID No. 1462, Seq. ID No. 1470, Seq. ID No. 1472, Seq. ID No. 1474, Seq. ID No. 1476, Seq. ID No. 1478, Seq. ID No. 1484, Seq. ID No. 1488, Seq. ID No. 1490, Seq. ID No. 1494, Seq. ID No. 1496, Seq. ID No. 1498, Seq. ID No. 1502, Seq. ID No. 1504, Seq. ID No. 1508, Seq. ID No. 1510, Seq. ID No. 1518, Seq. ID No. 1522, Seq. ID No. 1528, Seq. ID No. 1532, Seq. ID No. 1538, Seq. ID No. 1542, Seq. ID No. 1544, Seq. ID No. 1550, Seq. ID No. 1562, Seq. 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ID No. 2012, Seq. ID No. 2022, Seq. ID No. 2024, Seq. ID No. 2030, Seq. ID No. 2034, Seq. ID No. 2038, Seq. ID No. 2040, Seq. ID No. 2046, Seq. ID No. 2048, Seq. ID No. 2052, Seq. ID No. 2058, Seq. ID No. 2062, Seq. ID No. 2068, Seq. ID No. 2070, Seq. ID No. 2072, Seq. ID No. 2074, Seq. ID No. 2078, Seq. ID No. 2090, Seq. ID No. 2094, Seq. ID No. 2096, Seq. ID No. 2100, Seq. ID No. 2102, Seq. ID No. 2114, Seq. ID No. 2118, Seq. ID No. 2124, Seq. ID No. 2136, Seq. ID No. 2138, Seq. ID No. 2140, Seq. ID No. 2144, Seq. ID No. 2148, Seq. ID No. 2154, Seq. ID No. 2160, Seq. ID No. 2164, Seq. ID No. 2168, Seq. ID No. 2176, Seq. ID No. 2182, Seq. ID No. 2186, Seq. ID No. 2190, Seq. ID No. 2194, Seq. ID No. 2196, Seq. ID No. 2198, Seq. ID No. 2206, Seq. ID No. 2218, Seq. ID No. 2220, Seq. ID No. 2224, Seq. ID No. 2226, Seq. ID No. 2230, Seq. ID No. 2236, Seq. ID No. 2240, Seq. ID No. 2244, Seq. ID No. 2246, Seq. ID No. 2248, Seq. ID No. 2254, Seq. ID No. 2256, Seq. ID No. 2258, Seq. ID No. 2260, Seq. ID No. 2262, Seq. ID No. 2266, Seq. ID No. 2270, Seq. ID No. 2274, Seq. ID No. 2286, Seq. ID No. 2298, Seq. ID No. 2300, Seq. ID No. 2302, Seq. ID No. 2314, Seq. ID No. 2328, Seq. ID No. 2332, Seq. ID No. 2336, Seq. ID No. 2338, Seq. ID No. 2342, Seq. ID No. 2344, Seq. ID No. 2346, Seq. ID No. 2350, Seq. ID No. 2352, Seq. ID No. 2358, Seq. ID No. 2360, Seq. ID No. 2362, Seq. ID No. 2366, Seq. ID No. 2370, Seq. ID No. 2374, Seq. ID No. 2378, Seq. ID No. 2384, Seq. ID No. 2398, Seq. ID No. 2402, Seq. ID No. 2404, Seq. ID No. 2410, Seq. ID No. 2412, Seq. ID No. 2418, Seq. ID No. 2422, Seq. ID No. 2424, Seq. ID No. 2426, Seq. ID No. 2430, Seq. ID No. 2436, Seq. ID No. 2438, Seq. ID No. 2440, Seq. ID No. 2442, Seq. ID No. 2446, Seq. ID No. 2450, Seq. ID No. 2452, Seq. ID No. 2454, Seq. ID No. 2462, Seq. ID No. 2466, Seq. ID No. 2468, Seq. ID No. 2472, Seq. ID No. 2474, Seq. ID No. 2478, Seq. ID No. 2480, Seq. ID No. 2482, Seq. ID No. 2486, Seq. ID No. 2488, Seq. ID No. 2496, Seq. ID No. 2506, Seq. ID No. 2508, Seq. ID No. 2510, Seq. ID No. 2520, Seq. ID No. 2526, Seq. ID No. 2528, Seq. ID No. 2530, Seq. ID No. 2536, Seq. ID No. 2538, Seq. ID No. 2540, Seq. ID No. 2548, Seq. ID No. 2552, Seq. ID No. 2564, Seq. ID No. 2566, Seq. ID No. 2574, Seq. ID No. 2578, Seq. ID No. 2580, Seq. ID No. 2586, Seq. ID No. 2594, Seq. ID No. 2596, Seq. ID No. 2600, Seq. ID No. 2608, Seq. ID No. 2610, Seq. ID No. 2614, Seq. ID No. 2616, Seq. ID No. 2620, Seq. ID No. 2624, Seq. ID No. 2626, Seq. ID No. 2632, Seq. ID No. 2634, Seq. ID No. 2640, Seq. ID No. 2642, Seq. ID No. 2644, Seq. ID No. 2648, Seq. ID No. 2652, Seq. ID No. 2656, Seq. ID No. 2658, Seq. ID No. 2662, Seq. ID No. 2666, Seq. ID No. 2670, Seq. ID No. 2672, Seq. ID No. 2674, Seq. ID No. 2682, Seq. ID No. 2690, Seq. ID No. 2694, Seq. ID No. 2700, Seq. ID No. 2704, Seq. ID No. 2710, Seq. ID No. 2712, Seq. ID No. 2714, Seq. ID No. 2720, Seq. ID No. 2722, Seq. ID No. 2728, Seq. ID No. 2738, Seq. 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ID No. 2972, Seq. ID No. 2974, Seq. ID No. 2976, Seq. ID No. 2980, Seq. ID No. 2982, Seq. ID No. 2986, Seq. ID No. 2990, Seq. ID No. 2994, Seq. ID No. 3000, Seq. ID No. 3002, Seq. ID No. 3004, Seq. ID No. 3018, Seq. ID No. 3028, Seq. ID No. 3034, Seq. ID No. 3036, Seq. ID No. 3040, Seq. ID No. 3042, Seq. ID No. 3044, Seq. ID No. 3046, Seq. ID No. 3048, Seq. ID No. 3056, Seq. ID No. 3058, Seq. ID No. 3062, Seq. ID No. 3066, Seq. ID No. 3070, Seq. ID No. 3080, Seq. ID No. 3090, Seq. ID No. 3092, Seq. ID No. 3094, Seq. ID No. 3096, Seq. ID No. 3104, Seq. ID No. 3106, Seq. ID No. 3110, Seq. ID No. 3114, Seq. ID No. 3126, Seq. ID No. 3128, Seq. ID No. 3136, Seq. ID No. 3138, Seq. ID No. 3142, Seq. ID No. 3144, Seq. ID No. 3148, Seq. ID No. 3156, Seq. ID No. 3158, Seq. ID No. 3160, Seq. ID No. 3162, Seq. ID No. 3166, Seq. ID No. 3170, Seq. ID No. 3176, Seq. ID No. 3180, Seq. ID No. 3184, Seq. ID No. 3186, Seq. ID No. 3190, Seq. ID No. 3192, Seq. ID No. 3196, Seq. ID No. 3200, Seq. 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ID No. 3466, Seq. ID No. 3470, Seq. ID No. 3472, Seq. ID No. 3474, Seq. ID No. 3476, Seq. ID No. 3478, Seq. ID No. 3484, Seq. ID No. 3488, Seq. ID No. 3496, Seq. ID No. 3498, Seq. ID No. 3506, Seq. ID No. 3508, Seq. ID No. 3510, Seq. ID No. 3512, Seq. ID No. 3516, Seq. ID No. 3522, Seq. ID No. 3524, Seq. ID No. 3530, Seq. ID No. 3536, Seq. ID No. 3542, Seq. ID No. 3552, Seq. ID No. 3560, Seq. ID No. 3564, Seq. ID No. 3568, Seq. ID No. 3576, Seq. ID No. 3578, Seq. ID No. 3584, Seq. ID No. 3586, Seq. ID No. 3590, Seq. ID No. 3592, Seq. ID No. 3600, Seq. ID No. 3602, Seq. ID No. 3608, Seq. ID No. 3610, Seq. ID No. 3612, Seq. ID No. 3616, Seq. ID No. 3620, Seq. ID No. 3630, Seq. ID No. 3632, Seq. ID No. 3634, Seq. ID No. 3638, Seq. ID No. 3642, Seq. ID No. 3644, Seq. ID No. 3646, Seq. ID No. 3652, Seq. ID No. 3654, Seq. ID No. 3656, Seq. ID No. 3662, Seq. ID No. 3666, Seq. ID No. 3668, Seq. ID No. 3670, Seq. ID No. 3676, Seq. ID No. 3682, Seq. ID No. 3690, Seq. ID No. 3696, Seq. 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ID No. 4184, Seq. ID No. 4188, Seq. ID No. 4194, Seq. ID No. 4196, Seq. ID No. 4198, Seq. ID No. 4200, Seq. ID No. 4202, Seq. ID No. 4206, Seq. ID No. 4208, Seq. ID No. 4214, Seq. ID No. 4220, Seq. ID No. 4236, Seq. ID No. 4238, Seq. ID No. 4240, Seq. ID No. 4244, Seq. ID No. 4246, Seq. ID No. 4256, Seq. ID No. 4260, Seq. ID No. 4268, Seq. ID No. 4272, Seq. ID No. 4278, Seq. ID No. 4280, Seq. ID No. 4282, Seq. ID No. 4284, Seq. ID No. 4290, Seq. ID No. 4294, Seq. ID No. 4300, Seq. ID No. 4302, Seq. ID No. 4304, Seq. ID No. 4306, Seq. ID No. 4308, Seq. ID No. 4310, Seq. ID No. 4314, Seq. ID No. 4316, Seq. ID No. 4324, Seq. ID No. 4326, Seq. ID No. 4328, Seq. ID No. 4332, Seq. ID No. 4334, Seq. ID No. 4338, Seq. ID No. 4342, Seq. ID No. 4346, Seq. ID No. 4350, Seq. ID No. 4356, Seq. ID No. 4358, Seq. ID No. 4366, Seq. ID No. 4368, Seq. ID No. 4372, Seq. ID No. 4376, Seq. ID No. 4378, Seq. ID No. 4380, Seq. ID No. 4384, Seq. ID No. 4388, Seq. ID No. 4394, Seq. ID No. 4398, Seq. ID No. 4402, Seq. ID No. 4410, Seq. ID No. 4414, Seq. ID No. 4422, Seq. ID No. 4434, Seq. ID No. 4436, Seq. ID No. 4446, Seq. ID No. 4450, Seq. ID No. 4458, Seq. ID No. 4462, Seq. ID No. 4464, Seq. ID No. 4472, Seq. ID No. 4476, Seq. ID No. 4478, Seq. ID No. 4482, Seq. ID No. 4488, Seq. ID No. 4492, Seq. ID No. 4500, Seq. ID No. 4502, Seq. ID No. 4504, Seq. ID No. 4510, Seq. ID No. 4518, Seq. ID No. 4532, Seq. ID No. 4534, Seq. ID No. 4536, Seq. ID No. 4540, Seq. ID No. 4542, Seq. ID No. 4546, Seq. ID No. 4550, Seq. ID No. 4558, Seq. ID No. 4564, Seq. ID No. 4568, Seq. ID No. 4570, Seq. ID No. 4576, Seq. ID No. 4578, Seq. ID No. 4580, Seq. ID No. 4584, Seq. ID No. 4592, Seq. ID No. 4594, Seq. ID No. 4598, Seq. ID No. 4602, Seq. ID No. 4606, Seq. ID No. 4610, Seq. ID No. 4612, Seq. ID No. 4614, Seq. ID No. 4624, Seq. ID No. 4626, Seq. ID No. 4630, Seq. ID No. 4634, Seq. ID No. 4638, Seq. ID No. 4642, Seq. ID No. 4646, Seq. ID No. 4652, Seq. ID No. 4654, Seq. ID No. 4656, Seq. ID No. 4662, Seq. ID No. 4664, Seq. ID No. 4670, Seq. ID No. 4672, Seq. ID No. 4674, Seq. ID No. 4676, Seq. ID No. 4686, Seq. ID No. 4690, Seq. ID No. 4698, Seq. ID No. 4704, Seq. ID No. 4706, Seq. ID No. 4714, Seq. ID No. 4718, Seq. ID No. 4720, Seq. ID No. 4724, Seq. ID No. 4730, Seq. ID No. 4732, Seq. ID No. 4734, Seq. ID No. 4740, Seq. ID No. 4744, Seq. ID No. 4746, Seq. ID No. 4748, Seq. ID No. 4750, Seq. ID No. 4752, Seq. ID No. 4754, Seq. ID No. 4762, Seq. ID No. 4768, Seq. ID No. 4772, Seq. ID No. 4780, Seq. ID No. 4782, Seq. ID No. 4784, Seq. ID No. 4786, Seq. ID No. 4790, Seq. ID No. 4792, Seq. ID No. 4794, Seq. ID No. 4800, Seq. ID No. 4808, Seq. ID No. 4810, Seq. ID No. 4812, Seq. ID No. 4814, Seq. ID No. 4816, Seq. ID No. 4822, Seq. ID No. 4826, Seq. ID No. 4828, Seq. ID No. 4830, Seq. ID No. 4838, Seq. ID No. 4840, Seq. ID No. 4846, Seq. ID No. 4848, Seq. ID No. 4850, Seq. ID No. 4858, Seq. ID No. 4862, Seq. ID No. 4866, Seq. ID No. 4868, Seq. ID No. 4876, Seq. ID No. 4880, Seq. ID No. 4882, Seq. ID No. 4884, Seq. ID No. 4886, Seq. ID No. 4888, Seq. ID No. 4894, Seq. ID No. 4900, Seq. ID No. 4902, Seq. ID No. 4904, Seq. ID No. 4906, Seq. ID No. 4908, Seq. ID No. 4910, Seq. ID No. 4916, Seq. ID No. 4918, Seq. ID No. 4920, Seq. ID No. 4922, Seq. ID No. 4926, Seq. ID No. 4930, Seq. ID No. 4934, Seq. ID No. 4938, Seq. ID No. 4942, Seq. ID No. 4944, Seq. ID No. 4946, Seq. ID No. 4948, Seq. ID No. 4954, Seq. ID No. 4956, Seq. ID No. 4960, Seq. ID No. 4962, Seq. ID No. 4966, Seq. ID No. 4968, Seq. ID No. 4972, Seq. ID No. 4974, Seq. ID No. 4978, Seq. ID No. 4986, Seq. ID No. 4990, Seq. ID No. 4992, Seq. ID No. 4996, Seq. ID No. 4998, Seq. ID No. 5006, Seq. ID No. 5010, Seq. ID No. 5016, Seq. ID No. 5020, Seq. ID No. 5026, Seq. ID No. 5030, Seq. ID No. 5038, Seq. ID No. 5046, Seq. ID No. 5050, Seq. ID No. 5054, Seq. ID No. 5056, Seq. ID No. 5060, Seq. ID No. 5062, Seq. ID No. 5066, Seq. ID No. 5072, Seq. ID No. 5074, Seq. ID No. 5080, Seq. ID No. 5082, Seq. ID No. 5084, Seq. ID No. 5088, Seq. ID No. 5090, Seq. ID No. 5094, Seq. ID No. 5096, Seq. ID No. 5104, Seq. ID No. 5106, Seq. ID No. 5108, Seq. ID No. 5112, Seq. ID No. 5114, Seq. ID No. 5116, Seq. ID No. 5118, Seq. ID No. 5120, Seq. ID No. 5142, Seq. ID No. 5144, Seq. ID No. 5148, Seq. ID No. 5154, Seq. ID No. 5156, Seq. ID No. 5164, Seq. ID No. 5170, Seq. ID No. 5172, Seq. ID No. 5174, Seq. ID No. 5180, Seq. ID No. 5186, Seq. ID No. 5188, Seq. ID No. 5194, Seq. ID No. 5196, Seq. ID No. 5202, Seq. ID No. 5204, Seq. ID No. 5206, Seq. ID No. 5210, Seq. ID No. 5212, Seq. ID No. 5214, Seq. ID No. 5218, Seq. ID No. 5226, Seq. ID No. 5232, Seq. ID No. 5234, Seq. ID No. 5238, Seq. ID No. 5240, Seq. ID No. 5246, Seq. ID No. 5248, Seq. ID No. 5250, Seq. ID No. 5256, Seq. ID No. 5258, Seq. ID No. 5260, Seq. ID No. 5264, Seq. ID No. 5270, Seq. ID No. 5274, Seq. ID No. 5284, Seq. ID No. 5290, Seq. ID No. 5294, Seq. ID No. 5308, Seq. ID No. 5312, Seq. ID No. 5314, Seq. ID No. 5316, Seq. ID No. 5324, Seq. ID No. 5326, Seq. ID No. 5336, Seq. ID No. 5338, Seq. ID No. 5340, Seq. ID No. 5346, Seq. ID No. 5348, Seq. ID No. 5350, Seq. ID No. 5354, Seq. ID No. 5362, Seq. ID No. 5366, Seq. ID No. 5368, Seq. ID No. 5370, Seq. ID No. 5374, Seq. ID No. 5376, Seq. ID No. 5388, Seq. ID No. 5390, Seq. ID No. 5392, Seq. ID No. 5394, Seq. ID No. 5396, Seq. ID No. 5398, Seq. ID No. 5400, Seq. ID No. 5402, Seq. ID No. 5404, Seq. ID No. 5406, Seq. ID No. 5412, Seq. ID No. 5416, Seq. ID No. 5418, Seq. ID No. 5420, Seq. ID No. 5422, Seq. ID No. 5424, Seq. ID No. 5430, Seq. ID No. 5434, Seq. ID No. 5442, Seq. ID No. 5444, Seq. ID No. 5446, Seq. ID No. 5450, Seq. ID No. 5452, Seq. ID No. 5454, Seq. ID No. 5456, Seq. ID No. 5458, Seq. ID No. 5470, Seq. ID No. 5476, Seq. ID No. 5484, Seq. ID No. 5486, Seq. ID No. 5490, Seq. ID No. 5494, Seq. ID No. 5500, Seq. ID No. 5502, Seq. ID No. 5506, Seq. ID No. 5510, Seq. ID No. 5512, Seq. ID No. 5524, Seq. ID No. 5530, Seq. ID No. 5536, Seq. ID No. 5540, Seq. ID No. 5542, Seq. ID No. 5548, Seq. ID No. 5552, Seq. ID No. 5556, Seq. ID No. 5560, Seq. ID No. 5562, Seq. ID No. 5566, Seq. ID No. 5572, Seq. ID No. 5574, Seq. ID No. 5580, Seq. ID No. 5584, Seq. ID No. 5590, Seq. ID No. 5600, Seq. ID No. 5602, Seq. ID No. 5604, Seq. ID No. 5614, Seq. ID No. 5622, Seq. ID No. 5628, Seq. ID No. 5632, Seq. ID No. 5636, Seq. ID No. 5646, Seq. ID No. 5652, Seq. ID No. 5654, Seq. ID No. 5658, Seq. ID No. 5662, Seq. ID No. 5664, Seq. ID No. 5666, Seq. ID No. 5670, Seq. ID No. 5672, Seq. ID No. 5674, Seq. ID No. 5676, Seq. ID No. 5682, Seq. ID No. 5694, Seq. ID No. 5696, Seq. ID No. 5700, Seq. ID No. 5702, Seq. ID No. 5708, Seq. ID No. 5714, Seq. ID No. 5718, Seq. ID No. 5724, Seq. ID No. 5726, Seq. ID No. 5732, Seq. ID No. 5738, Seq. ID No. 5748, Seq. ID No. 5752, Seq. ID No. 5756, Seq. ID No. 5760, Seq. ID No. 5772, Seq. ID No. 5774, Seq. ID No. 5778, Seq. ID No. 5780, Seq. ID No. 5782, Seq. ID No. 5786, Seq. ID No. 5794, Seq. ID No. 5800, Seq. ID No. 5806, Seq. ID No. 5812, Seq. ID No. 5816, Seq. ID No. 5818, Seq. ID No. 5824, Seq. ID No. 5832, Seq. ID No. 5836, Seq. ID No. 5840, Seq. ID No. 5844, Seq. ID No. 5848, Seq. ID No. 5850, Seq. ID No. 5852, Seq. ID No. 5854, Seq. ID No. 5856, Seq. ID No. 5858, Seq. ID No. 5862, Seq. ID No. 5868, Seq. ID No. 5876, Seq. ID No. 5878, Seq. ID No. 5882, Seq. ID No. 5890, Seq. ID No. 5896, Seq. ID No. 5898, Seq. ID No. 5902, Seq. ID No. 5904, Seq. ID No. 5908, Seq. ID No. 5914, Seq. ID No. 5916, Seq. ID No. 5918, Seq. ID No. 5920, Seq. ID No. 5926, Seq. ID No. 5932, Seq. ID No. 5934, Seq. ID No. 5936, Seq. ID No. 5942, Seq. ID No. 5944, Seq. ID No. 5946, Seq. ID No. 5950, Seq. ID No. 5956, Seq. ID No. 5958, Seq. ID No. 5960, Seq. ID No. 5968, Seq. ID No. 5972, Seq. ID No. 5976, Seq. ID No. 5978, Seq. ID No. 5982, Seq. ID No. 5984, Seq. ID No. 5986, Seq. ID No. 5990, Seq. ID No. 5992, Seq. ID No. 5996, Seq. ID No. 5998, Seq. ID No. 6004, Seq. ID No. 6006, Seq. ID No. 6008, Seq. ID No. 6016, Seq. ID No. 6018, Seq. ID No. 6020, Seq. ID No. 6024, Seq. ID No. 6030, Seq. ID No. 6034, Seq. ID No. 6036, Seq. ID No. 6038, Seq. ID No. 6044, Seq. ID No. 6050, Seq. ID No. 6056, Seq. ID No. 6066, Seq. ID No. 6070, Seq. ID No. 6076, Seq. ID No. 6082, Seq. ID No. 6084, Seq. ID No. 6088, Seq. ID No. 6096, Seq. ID No. 6098, Seq. ID No. 6100, Seq. ID No. 6104, Seq. ID No. 6106, Seq. ID No. 6114, Seq. ID No. 6116, Seq. ID No. 6120, Seq. ID No. 6126, Seq. ID No. 6128, Seq. ID No. 6130, Seq. ID No. 6132, Seq. ID No. 6134, Seq. ID No. 6142, Seq. ID No. 6144, Seq. ID No. 6148, Seq. ID No. 6154, Seq. ID No. 6166, Seq. ID No. 6170, Seq. ID No. 6172, Seq. ID No. 6174, Seq. ID No. 6178, Seq. ID No. 6180, Seq. ID No. 6188, Seq. ID No. 6194, Seq. ID No. 6202, Seq. ID No. 6208, Seq. ID No. 6212, Seq. ID No. 6216, Seq. ID No. 6220, Seq. ID No. 6232, Seq. ID No. 6236, Seq. ID No. 6244, Seq. ID No. 6248, Seq. ID No. 6252, Seq. ID No. 6256, Seq. ID No. 6262, Seq. ID No. 6264, Seq. ID No. 6270, Seq. ID No. 6276, Seq. ID No. 6278, Seq. ID No. 6280, Seq. ID No. 6288, Seq. ID No. 6292, Seq. ID No. 6300, Seq. ID No. 6306, Seq. ID No. 6308, Seq. ID No. 6314, Seq. ID No. 6316, Seq. ID No. 6322, Seq. ID No. 6324, Seq. ID No. 6326, Seq. ID No. 6332, Seq. ID No. 6336, Seq. ID No. 6340, Seq. ID No. 6342, Seq. ID No. 6344, Seq. ID No. 6346, Seq. ID No. 6348, Seq. ID No. 6356, Seq. ID No. 6360, Seq. ID No. 6362, Seq. ID No. 6366, Seq. ID No. 6370, Seq. ID No. 6372, Seq. ID No. 6376, Seq. ID No. 6378, Seq. ID No. 6380, Seq. ID No. 6388, Seq. ID No. 6392, Seq. ID No. 6398, Seq. ID No. 6402, Seq. ID No. 6406, Seq. ID No. 6410, Seq. ID No. 6414, Seq. ID No. 6418, Seq. ID No. 6420, Seq. ID No. 6424, Seq. ID No. 6430, Seq. ID No. 6434, Seq. ID No. 6436, Seq. ID No. 6440, Seq. ID No. 6446, Seq. ID No. 6448, Seq. ID No. 6452, Seq. ID No. 6456, Seq. ID No. 6460, Seq. ID No. 6462, Seq. ID No. 6464, Seq. ID No. 6476, Seq. ID No. 6482, Seq. ID No. 6484, Seq. ID No. 6486, Seq. ID No. 6488, Seq. ID No. 6490, Seq. ID No. 6492, Seq. ID No. 6494, Seq. ID No. 6496, Seq. ID No. 6500, Seq. ID No. 6506, Seq. ID No. 6510, Seq. ID No. 6514, Seq. ID No. 6520, Seq. ID No. 6522, Seq. ID No. 6526, Seq. ID No. 6528, Seq. ID No. 6532, Seq. ID No. 6534, Seq. ID No. 6536, Seq. ID No. 6546, Seq. ID No. 6552, Seq. ID No. 6554, Seq. ID No. 6560, Seq. ID No. 6562, Seq. ID No. 6564, Seq. ID No. 6566, Seq. ID No. 6568, Seq. ID No. 6570, Seq. ID No. 6576, Seq. ID No. 6580, Seq. ID No. 6584, Seq. ID No. 6586, Seq. ID No. 6592, Seq. ID No. 6596, Seq. ID No. 6606, Seq. ID No. 6608, Seq. ID No. 6612, Seq. ID No. 6616, Seq. ID No. 6618, Seq. ID No. 6620, Seq. ID No. 6624, Seq. ID No. 6626, Seq. ID No. 6630, Seq. ID No. 6634, Seq. ID No. 6636, Seq. ID No. 6642, and Seq. ID No. 6648.

In yet another preferred embodiment, the polypeptide is selected from the Alloiococcus otitidis polypeptides identified by the Applicants' assignee's ORF finder program that searches for an ATG, GTG or TTG Start codon between a Stop-Stop region, and wherein the polypeptide is selected from one Seq. ID No. 2, Seq. ID No. 6, Seq. ID No. 12, Seq. ID No. 14, Seq. ID No. 16, Seq. ID No. 18, Seq. ID No. 20, Seq. ID No. 22, Seq. ID No. 24, Seq. ID No. 28, Seq. ID No. 30, Seq. ID No. 32, Seq. ID No. 36, Seq. ID No. 38, Seq. ID No. 42, Seq. ID No. 44, Seq. ID No. 46, Seq. ID No. 48, Seq. ID No. 50, Seq. ID No. 52, Seq. ID No. 54, Seq. ID No. 56, Seq. ID No. 58, Seq. ID No. 60, Seq. ID No. 66, Seq. ID No. 68, Seq. ID No. 76, Seq. ID No. 78, Seq. ID No. 80, Seq. ID No. 82, Seq. ID No. 84, Seq. ID No. 90, Seq. ID No. 92, Seq. ID No. 94, Seq. ID No. 98, Seq. ID No. 100, Seq. ID No. 104, Seq. ID No. 106, Seq. ID No. 108, Seq. ID No. 110, Seq. ID No. 112, Seq. ID No. 114, Seq. ID No. 116, Seq. ID No. 118, Seq. ID No. 120, Seq. ID No. 122, Seq. ID No. 128, Seq. ID No. 130, Seq. ID No. 132, Seq. ID No. 134, Seq. ID No. 136, Seq. ID No. 138, Seq. ID No. 140, Seq. ID No. 144, Seq. ID No. 146, Seq. ID No. 148, Seq. ID No. 150, Seq. ID No. 154, Seq. ID No. 156, Seq. ID No. 158, Seq. ID No. 160, Seq. ID No. 162, Seq. ID No. 164, Seq. ID No. 166, Seq. ID No. 168, Seq. ID No. 170, Seq. ID No. 172, Seq. ID No. 176, Seq. ID No. 178, Seq. ID No. 180, Seq. ID No. 182, Seq. ID No. 184, Seq. ID No. 188, Seq. ID No. 192, Seq. ID No. 194, Seq. ID No. 196, Seq. ID No. 202, Seq. ID No. 206, Seq. ID No. 208, Seq. ID No. 216, Seq. ID No. 220, Seq. ID No. 222, Seq. ID No. 224, Seq. ID No. 226, Seq. ID No. 228, Seq. ID No. 232, Seq. ID No. 234, Seq. ID No. 240, Seq. ID No. 244, Seq. ID No. 246, Seq. ID No. 248, Seq. ID No. 254, Seq. ID No. 258, Seq. ID No. 260, Seq. ID No. 262, Seq. ID No. 264, Seq. ID No. 266, Seq. ID No. 268, Seq. ID No. 270, Seq. ID No. 274, Seq. ID No. 278, Seq. ID No. 280, Seq. ID No. 282, Seq. ID No. 284, Seq. ID No. 292, Seq. ID No. 294, Seq. ID No. 298, Seq. ID No. 302, Seq. ID No. 306, Seq. ID No. 308, Seq. ID No. 310, Seq. ID No. 314, Seq. ID No. 318, Seq. ID No. 322, Seq. ID No. 324, Seq. ID No. 326, Seq. ID No. 332, Seq. ID No. 334, Seq. ID No. 336, Seq. ID No. 338, Seq. ID No. 340, Seq. ID No. 344, Seq. ID No. 346, Seq. ID No. 348, Seq. ID No. 350, Seq. ID No. 354, Seq. ID No. 356, Seq. ID No. 358, Seq. ID No. 360, Seq. ID No. 362, Seq. ID No. 364, Seq. ID No. 366, Seq. ID No. 368, Seq. ID No. 370, Seq. ID No. 372, Seq. ID No. 376, Seq. ID No. 378, Seq. ID No. 380, Seq. ID No. 384, Seq. ID No. 386, Seq. ID No. 388, Seq. ID No. 390, Seq. ID No. 392, Seq. ID No. 394, Seq. ID No. 398, Seq. ID No. 402, Seq. ID No. 404, Seq. ID No. 406, Seq. ID No. 408, Seq. ID No. 410, Seq. ID No. 416, Seq. ID No. 424, Seq. ID No. 426, Seq. ID No. 428, Seq. ID No. 430, Seq. ID No. 432, Seq. ID No. 434, Seq. ID No. 436, Seq. ID No. 438, Seq. ID No. 440, Seq. ID No. 442, Seq. ID No. 444, Seq. ID No. 446, Seq. ID No. 448, Seq. ID No. 452, Seq. ID No. 454, Seq. ID No. 456, Seq. ID No. 458, Seq. ID No. 462, Seq. ID No. 464, Seq. ID No. 468, Seq. ID No. 470, Seq. ID No. 472, Seq. ID No. 474, Seq. ID No. 476, Seq. ID No. 478, Seq. ID No. 480, Seq. ID No. 482, Seq. ID No. 484, Seq. ID No. 486, Seq. ID No. 490, Seq. ID No. 492, Seq. ID No. 494, Seq. ID No. 496, Seq. ID No. 502, Seq. ID No. 506, Seq. ID No. 508, Seq. ID No. 512, Seq. ID No. 516, Seq. ID No. 518, Seq. ID No. 524, Seq. ID No. 530, Seq. ID No. 532, Seq. ID No. 534, Seq. ID No. 538, Seq. ID No. 540, Seq. ID No. 544, Seq. ID No. 548, Seq. ID No. 550, Seq. ID No. 552, Seq. ID No. 554, Seq. ID No. 556, Seq. ID No. 558, Seq. ID No. 560, Seq. ID No. 562, Seq. ID No. 566, Seq. ID No. 570, Seq. ID No. 572, Seq. ID No. 574, Seq. ID No. 576, Seq. ID No. 580, Seq. ID No. 582, Seq. ID No. 586, Seq. ID No. 588, Seq. ID No. 590, Seq. ID No. 592, Seq. ID No. 594, Seq. ID No. 596, Seq. ID No. 598, Seq. ID No. 600, Seq. ID No. 602, Seq. ID No. 604, Seq. ID No. 606, Seq. ID No. 610, Seq. ID No. 614, Seq. ID No. 616, Seq. ID No. 618, Seq. ID No. 620, Seq. ID No. 622, Seq. ID No. 624, Seq. ID No. 626, Seq. ID No. 628, Seq. ID No. 636, Seq. ID No. 638, Seq. ID No. 644, Seq. ID No. 646, Seq. ID No. 648, Seq. ID No. 650, Seq. ID No. 656, Seq. ID No. 664, Seq. ID No. 666, Seq. ID No. 668, Seq. ID No. 670, Seq. ID No. 676, Seq. ID No. 682, Seq. ID No. 684, Seq. ID No. 688, Seq. ID No. 690, Seq. ID No. 692, Seq. ID No. 696, Seq. ID No. 698, Seq. ID No. 700, Seq. ID No. 702, Seq. ID No. 704, Seq. ID No. 706, Seq. ID No. 708, Seq. ID No. 710, Seq. ID No. 714, Seq. ID No. 726, Seq. ID No. 728, Seq. ID No. 730, Seq. ID No. 732, Seq. ID No. 734, Seq. ID No. 736, Seq. ID No. 740, Seq. ID No. 742, Seq. ID No. 746, Seq. ID No. 748, Seq. ID No. 750, Seq. ID No. 752, Seq. ID No. 754, Seq. ID No. 760, Seq. ID No. 764, Seq. ID No. 766, Seq. ID No. 774, Seq. ID No. 776, Seq. ID No. 782, Seq. ID No. 784, Seq. ID No. 788, Seq. ID No. 794, Seq. ID No. 796, Seq. ID No. 800, Seq. ID No. 802, Seq. ID No. 806, Seq. ID No. 808, Seq. ID No. 810, Seq. ID No. 812, Seq. ID No. 814, Seq. ID No. 816, Seq. ID No. 818, Seq. ID No. 820, Seq. ID No. 822, Seq. ID No. 824, Seq. ID No. 828, Seq. ID No. 830, Seq. ID No. 832, Seq. ID No. 836, Seq. ID No. 838, Seq. ID No. 840, Seq. ID No. 844, Seq. ID No. 846, Seq. ID No. 848, Seq. ID No. 856, Seq. ID No. 860, Seq. ID No. 862, Seq. ID No. 866, Seq. ID No. 868, Seq. ID No. 872, Seq. ID No. 874, Seq. ID No. 876, Seq. ID No. 878, Seq. ID No. 880, Seq. ID No. 882, Seq. ID No. 886, Seq. ID No. 896, Seq. ID No. 898, Seq. ID No. 900, Seq. ID No. 902, Seq. ID No. 904, Seq. ID No. 906, Seq. ID No. 908, Seq. ID No. 910, Seq. ID No. 914, Seq. ID No. 916, Seq. ID No. 922, Seq. ID No. 924, Seq. ID No. 926, Seq. ID No. 932, Seq. ID No. 934, Seq. ID No. 936, Seq. ID No. 938, Seq. ID No. 940, Seq. ID No. 942, Seq. ID No. 944, Seq. ID No. 948, Seq. ID No. 950, Seq. ID No. 952, Seq. ID No. 954, Seq. ID No. 956, Seq. ID No. 958, Seq. ID No. 962, Seq. ID No. 964, Seq. ID No. 966, Seq. ID No. 968, Seq. ID No. 970, Seq. ID No. 972, Seq. ID No. 974, Seq. ID No. 976, Seq. ID No. 982, Seq. ID No. 984, Seq. ID No. 986, Seq. ID No. 988, Seq. ID No. 990, Seq. ID No. 992, Seq. ID No. 994, Seq. ID No. 996, Seq. ID No. 998, Seq. ID No. 1002, Seq. ID No. 1004, Seq. ID No. 1006, Seq. ID No. 1008, Seq. ID No. 1010, Seq. ID No. 1018, Seq. ID No. 1020, Seq. ID No. 1024, Seq. ID No. 1026, Seq. ID No. 1028, Seq. ID No. 1040, Seq. ID No. 1042, Seq. ID No. 1044, Seq. ID No. 1046, Seq. ID No. 1048, Seq. ID No. 1050, Seq. ID No. 1052, Seq. ID No. 1058, Seq. ID No. 1060, Seq. ID No. 1062, Seq. ID No. 1066, Seq. ID No. 1070, Seq. ID No. 1076, Seq. ID No. 1078, Seq. ID No. 1080, Seq. ID No. 1082, Seq. ID No. 1084, Seq. ID No. 1086, Seq. ID No. 1088, Seq. ID No. 1092, Seq. ID No. 1094, Seq. ID No. 1096, Seq. ID No. 1098, Seq. ID No. 1100, Seq. ID No. 1102, Seq. ID No. 1104, Seq. ID No. 1108, Seq. ID No. 1110, Seq. ID No. 1112, Seq. ID No. 1114, Seq. ID No. 1116, Seq. ID No. 1120, Seq. ID No. 1122, Seq. ID No. 1124, Seq. ID No. 1126, Seq. ID No. 1128, Seq. ID No. 1130, Seq. ID No. 1132, Seq. ID No. 1138, Seq. ID No. 1140, Seq. ID No. 1142, Seq. ID No. 1144, Seq. ID No. 1146, Seq. ID No. 1148, Seq. ID No. 1150, Seq. ID No. 1152, Seq. ID No. 1154, Seq. ID No. 1156, Seq. ID No. 1158, Seq. ID No. 1160, Seq. ID No. 1162, Seq. ID No. 1164, Seq. ID No. 1172, Seq. ID No. 1176, Seq. ID No. 1178, Seq. ID No. 1180, Seq. ID No. 1182, Seq. ID No. 1188, Seq. ID No. 1192, Seq. ID No. 1194, Seq. ID No. 1196, Seq. ID No. 1198, Seq. ID No. 1202, Seq. ID No. 1204, Seq. ID No. 1206, Seq. ID No. 1208, Seq. ID No. 1212, Seq. ID No. 1214, Seq. ID No. 1216, Seq. ID No. 1218, Seq. ID No. 1222, Seq. ID No. 1224, Seq. ID No. 1226, Seq. ID No. 1232, Seq. ID No. 1234, Seq. ID No. 1238, Seq. ID No. 1240, Seq. ID No. 1242, Seq. ID No. 1246, Seq. ID No. 1248, Seq. ID No. 1250, Seq. ID No. 1252, Seq. ID No. 1254, Seq. ID No. 1256, Seq. ID No. 1258, Seq. ID No. 1260, Seq. ID No. 1262, Seq. ID No. 1264, Seq. ID No. 1272, Seq. ID No. 1274, Seq. ID No. 1276, Seq. ID No. 1278, Seq. ID No. 1280, Seq. ID No. 1286, Seq. ID No. 1290, Seq. ID No. 1292, Seq. ID No. 1294, Seq. ID No. 1296, Seq. ID No. 1298, Seq. ID No. 1300, Seq. ID No. 1302, Seq. ID No. 1304, Seq. ID No. 1306, Seq. ID No. 1308, Seq. ID No. 1310, Seq. ID No. 1312, Seq. ID No. 1314, Seq. ID No. 1318, Seq. ID No. 1320, Seq. ID No. 1322, Seq. ID No. 1332, Seq. ID No. 1334, Seq. ID No. 1336, Seq. ID No. 1338, Seq. ID No. 1340, Seq. ID No. 1344, Seq. ID No. 1346, Seq. ID No. 1348, Seq. ID No. 1350, Seq. ID No. 1352, Seq. ID No. 1360, Seq. ID No. 1362, Seq. ID No. 1364, Seq. ID No. 1366, Seq. ID No. 1370, Seq. ID No. 1372, Seq. ID No. 1376, Seq. ID No. 1378, Seq. ID No. 1382, Seq. ID No. 1384, Seq. ID No. 1386, Seq. ID No. 1388, Seq. ID No. 1390, Seq. ID No. 1392, Seq. ID No. 1394, Seq. ID No. 1402, Seq. ID No. 1404, Seq. ID No. 1408, Seq. ID No. 1410, Seq. ID No. 1412, Seq. ID No. 1414, Seq. ID No. 1416, Seq. ID No. 1420, Seq. ID No. 1422, Seq. ID No. 1424, Seq. ID No. 1426, Seq. ID No. 1428, Seq. ID No. 1430, Seq. ID No. 1434, Seq. ID No. 1438, Seq. ID No. 1442, Seq. ID No. 1444, Seq. ID No. 1448, Seq. ID No. 1450, Seq. ID No. 1452, Seq. ID No. 1456, Seq. ID No. 1460, Seq. ID No. 1464, Seq. ID No. 1466, Seq. ID No. 1468, Seq. ID No. 1470, Seq. ID No. 1472, Seq. ID No. 1474, Seq. ID No. 1476, Seq. ID No. 1478, Seq. ID No. 1480, Seq. ID No. 1484, Seq. ID No. 1486, Seq. ID No. 1488, Seq. ID No. 1492, Seq. ID No. 1494, Seq. ID No. 1496, Seq. ID No. 1498, Seq. ID No. 1500, Seq. ID No. 1502, Seq. ID No. 1506, Seq. ID No. 1508, Seq. ID No. 1512, Seq. ID No. 1518, Seq. ID No. 1520, Seq. ID No. 1524, Seq. ID No. 1526, Seq. ID No. 1528, Seq. ID No. 1532, Seq. ID No. 1540, Seq. ID No. 1544, Seq. ID No. 1550, Seq. ID No. 1552, Seq. ID No. 1554, Seq. ID No. 1556, Seq. ID No. 1558, Seq. ID No. 1562, Seq. ID No. 1564, Seq. ID No. 1566, Seq. ID No. 1568, Seq. ID No. 1572, Seq. ID No. 1574, Seq. ID No. 1576, Seq. ID No. 1578, Seq. ID No. 1580, Seq. ID No. 1582, Seq. ID No. 1590, Seq. ID No. 1594, Seq. ID No. 1596, Seq. ID No. 1598, Seq. ID No. 1600, Seq. ID No. 1602, Seq. ID No. 1608, Seq. ID No. 1612, Seq. ID No. 1614, Seq. ID No. 1616, Seq. ID No. 1618, Seq. ID No. 1620, Seq. ID No. 1624, Seq. ID No. 1626, Seq. ID No. 1628, Seq. ID No. 1634, Seq. ID No. 1638, Seq. ID No. 1640, Seq. ID No. 1642, Seq. ID No. 1644, Seq. ID No. 1648, Seq. ID No. 1652, Seq. ID No. 1654, Seq. ID No. 1656, Seq. ID No. 1658, Seq. ID No. 1662, Seq. ID No. 1664, Seq. ID No. 1666, Seq. ID No. 1670, Seq. ID No. 1676, Seq. ID No. 1680, Seq. ID No. 1682, Seq. ID No. 1686, Seq. ID No. 1688, Seq. ID No. 1690, Seq. ID No. 1692, Seq. ID No. 1694, Seq. ID No. 1696, Seq. ID No. 1698, Seq. ID No. 1700, Seq. ID No. 1704, Seq. ID No. 1706, Seq. ID No. 1708, Seq. ID No. 1712, Seq. ID No. 1714, Seq. ID No. 1716, Seq. ID No. 1718, Seq. ID No. 1720, Seq. ID No. 1722, Seq. ID No. 1724, Seq. ID No. 1728, Seq. ID No. 1730, Seq. ID No. 1736, Seq. ID No. 1738, Seq. ID No. 1740, Seq. ID No. 1742, Seq. ID No. 1748, Seq. ID No. 1750, Seq. ID No. 1752, Seq. ID No. 1756, Seq. ID No. 1758, Seq. ID No. 1760, Seq. ID No. 1764, Seq. ID No. 1770, Seq. ID No. 1772, Seq. ID No. 1776, Seq. ID No. 1778, Seq. ID No. 1780, Seq. ID No. 1782, Seq. ID No. 1784, Seq. ID No. 1786, Seq. ID No. 1790, Seq. ID No. 1792, Seq. ID No. 1794, Seq. ID No. 1796, Seq. ID No. 1798, Seq. ID No. 1806, Seq. ID No. 1810, Seq. ID No. 1812, Seq. ID No. 1814, Seq. ID No. 1816, Seq. ID No. 1818, Seq. ID No. 1820, Seq. ID No. 1822, Seq. ID No. 1824, Seq. ID No. 1826, Seq. ID No. 1830, Seq. ID No. 1834, Seq. ID No. 1842, Seq. ID No. 1844, Seq. ID No. 1846, Seq. ID No. 1848, Seq. ID No. 1850, Seq. ID No. 1854, Seq. ID No. 1856, Seq. ID No. 1858, Seq. ID No. 1860, Seq. ID No. 1862, Seq. ID No. 1864, Seq. ID No. 1866, Seq. ID No. 1868, Seq. ID No. 1872, Seq. ID No. 1874, Seq. ID No. 1876, Seq. ID No. 1878, Seq. ID No. 1882, Seq. ID No. 1884, Seq. ID No. 1886, Seq. ID No. 1888, Seq. ID No. 1890, Seq. ID No. 1896, Seq. ID No. 1904, Seq. ID No. 1906, Seq. ID No. 1908, Seq. ID No. 1912, Seq. ID No. 1914, Seq. ID No. 1916, Seq. ID No. 1920, Seq. ID No. 1924, Seq. ID No. 1926, Seq. ID No. 1928, Seq. ID No. 1930, Seq. ID No. 1932, Seq. ID No. 1936, Seq. ID No. 1942, Seq. ID No. 1944, Seq. ID No. 1946, Seq. ID No. 1948, Seq. ID No. 1950, Seq. ID No. 1952, Seq. ID No. 1954, Seq. ID No. 1960, Seq. ID No. 1962, Seq. ID No. 1964, Seq. ID No. 1966, Seq. ID No. 1968, Seq. ID No. 1970, Seq. ID No. 1972, Seq. ID No. 1980, Seq. ID No. 1984, Seq. ID No. 1986, Seq. ID No. 1988, Seq. ID No. 1990, Seq. ID No. 1992, Seq. ID No. 1996, Seq. ID No. 1998, Seq. ID No. 2000, Seq. ID No. 2002, Seq. ID No. 2004, Seq. ID No. 2006, Seq. ID No. 2008, Seq. ID No. 2016, Seq. ID No. 2020, Seq. ID No. 2022, Seq. ID No. 2026, Seq. ID No. 2028, Seq. ID No. 2030, Seq. ID No. 2032, Seq. ID No. 2036, Seq. ID No. 2038, Seq. ID No. 2042, Seq. ID No. 2044, Seq. ID No. 2046, Seq. ID No. 2048, Seq. ID No. 2054, Seq. ID No. 2056, Seq. ID No. 2060, Seq. ID No. 2064, Seq. ID No. 2066, Seq. ID No. 2068, Seq. ID No. 2070, Seq. ID No. 2072, Seq. ID No. 2074, Seq. ID No. 2076, Seq. ID No. 2078, Seq. ID No. 2080, Seq. ID No. 2082, Seq. ID No. 2084, Seq. ID No. 2086, Seq. ID No. 2090, Seq. ID No. 2092, Seq. ID No. 2094, Seq. ID No. 2098, Seq. ID No. 2100, Seq. ID No. 2102, Seq. ID No. 2104, Seq. ID No. 2108, Seq. ID No. 2110, Seq. ID No. 2112, Seq. ID No. 2116, Seq. ID No. 2118, Seq. ID No. 2120, Seq. ID No. 2126, Seq. ID No. 2128, Seq. ID No. 2130, Seq. ID No. 2132, Seq. ID No. 2134, Seq. ID No. 2136, Seq. ID No. 2138, Seq. ID No. 2142, Seq. ID No. 2144, Seq. ID No. 2146, Seq. ID No. 2150, Seq. ID No. 2152, Seq. ID No. 2154, Seq. ID No. 2156, Seq. ID No. 2158, Seq. ID No. 2160, Seq. ID No. 2162, Seq. ID No. 2166, Seq. ID No. 2168, Seq. ID No. 2170, Seq. ID No. 2180, Seq. ID No. 2182, Seq. ID No. 2184, Seq. ID No. 2190, Seq. ID No. 2192, Seq. ID No. 2196, Seq. ID No. 2198, Seq. ID No. 2200, Seq. ID No. 2202, Seq. ID No. 2204, Seq. ID No. 2206, Seq. ID No. 2208, Seq. ID No. 2210, Seq. ID No. 2212, Seq. ID No. 2214, Seq. ID No. 2216, Seq. ID No. 2218, Seq. ID No. 2222, Seq. ID No. 2224, Seq. ID No. 2228, Seq. ID No. 2230, Seq. ID No. 2236, Seq. ID No. 2242, Seq. ID No. 2246, Seq. ID No. 2248, Seq. ID No. 2252, Seq. ID No. 2254, Seq. ID No. 2258, Seq. ID No. 2260, Seq. ID No. 2262, Seq. ID No. 2264, Seq. ID No. 2266, Seq. ID No. 2268, Seq. ID No. 2270, Seq. ID No. 2276, Seq. ID No. 2278, Seq. ID No. 2280, Seq. ID No. 2286, Seq. ID No. 2288, Seq. ID No. 2298, Seq. ID No. 2300, Seq. ID No. 2302, Seq. ID No. 2310, Seq. ID No. 2312, Seq. ID No. 2316, Seq. ID No. 2328, Seq. ID No. 2330, Seq. ID No. 2334, Seq. ID No. 2344, Seq. ID No. 2346, Seq. ID No. 2350, Seq. ID No. 2352, Seq. ID No. 2358, Seq. ID No. 2364, Seq. ID No. 2366, Seq. ID No. 2368, Seq. ID No. 2370, Seq. ID No. 2372, Seq. ID No. 2374, Seq. ID No. 2376, Seq. ID No. 2380, Seq. ID No. 2382, Seq. ID No. 2386, Seq. ID No. 2388, Seq. ID No. 2392, Seq. ID No. 2394, Seq. ID No. 2396, Seq. ID No. 2398, Seq. ID No. 2400, Seq. ID No. 2402, Seq. ID No. 2406, Seq. ID No. 2410, Seq. ID No. 2414, Seq. ID No. 2416, Seq. ID No. 2418, Seq. ID No. 2422, Seq. ID No. 2424, Seq. ID No. 2426, Seq. ID No. 2428, Seq. ID No. 2430, Seq. ID No. 2436, Seq. ID No. 2438, Seq. ID No. 2446, Seq. ID No. 2448, Seq. ID No. 2450, Seq. ID No. 2452, Seq. ID No. 2454, Seq. ID No. 2456, Seq. ID No. 2458, Seq. ID No. 2460, Seq. ID No. 2462, Seq. ID No. 2464, Seq. ID No. 2466, Seq. ID No. 2470, Seq. ID No. 2472, Seq. ID No. 2476, Seq. ID No. 2482, Seq. ID No. 2484, Seq. ID No. 2486, Seq. ID No. 2492, Seq. ID No. 2494, Seq. ID No. 2496, Seq. ID No. 2500, Seq. ID No. 2502, Seq. ID No. 2504, Seq. ID No. 2506, Seq. ID No. 2508, Seq. ID No. 2512, Seq. ID No. 2514, Seq. ID No. 2518, Seq. ID No. 2520, Seq. ID No. 2522, Seq. ID No. 2526, Seq. ID No. 2530, Seq. ID No. 2534, Seq. ID No. 2536, Seq. ID No. 2538, Seq. ID No. 2540, Seq. ID No. 2548, Seq. ID No. 2550, Seq. ID No. 2552, Seq. ID No. 2554, Seq. ID No. 2560, Seq. ID No. 2562, Seq. ID No. 2564, Seq. ID No. 2566, Seq. ID No. 2574, Seq. ID No. 2576, Seq. ID No. 2578, Seq. ID No. 2580, Seq. ID No. 2582, Seq. ID No. 2588, Seq. ID No. 2590, Seq. ID No. 2592, Seq. ID No. 2594, Seq. ID No. 2596, Seq. ID No. 2600, Seq. ID No. 2604, Seq. ID No. 2606, Seq. ID No. 2608, Seq. ID No. 2610, Seq. ID No. 2612, Seq. ID No. 2614, Seq. ID No. 2618, Seq. ID No. 2620, Seq. ID No. 2624, Seq. ID No. 2626, Seq. ID No. 2628, Seq. ID No. 2630, Seq. ID No. 2632, Seq. ID No. 2634, Seq. ID No. 2636, Seq. ID No. 2638, Seq. ID No. 2640, Seq. ID No. 2642, Seq. ID No. 2644, Seq. ID No. 2646, Seq. ID No. 2648, Seq. ID No. 2650, Seq. ID No. 2652, Seq. ID No. 2654, Seq. ID No. 2656, Seq. ID No. 2660, Seq. ID No. 2664, Seq. ID No. 2668, Seq. ID No. 2670, Seq. ID No. 2672, Seq. ID No. 2676, Seq. ID No. 2678, Seq. ID No. 2684, Seq. ID No. 2686, Seq. ID No. 2688, Seq. ID No. 2690, Seq. ID No. 2692, Seq. ID No. 2694, Seq. ID No. 2696, Seq. ID No. 2698, Seq. ID No. 2700, Seq. ID No. 2704, Seq. ID No. 2710, Seq. ID No. 2712, Seq. ID No. 2716, Seq. ID No. 2718, Seq. ID No. 2720, Seq. ID No. 2724, Seq. ID No. 2726, Seq. ID No. 2728, Seq. ID No. 2730, Seq. ID No. 2732, Seq. ID No. 2736, Seq. ID No. 2738, Seq. ID No. 2740, Seq. ID No. 2750, Seq. ID No. 2752, Seq. ID No. 2754, Seq. ID No. 2756, Seq. ID No. 2760, Seq. ID No. 2766, Seq. ID No. 2768, Seq. ID No. 2770, Seq. ID No. 2772, Seq. ID No. 2774, Seq. ID No. 2776, Seq. ID No. 2780, Seq. ID No. 2782, Seq. ID No. 2784, Seq. ID No. 2788, Seq. ID No. 2790, Seq. ID No. 2792, Seq. ID No. 2794, Seq. ID No. 2796, Seq. ID No. 2798, Seq. ID No. 2800, Seq. ID No. 2802, Seq. ID No. 2804, Seq. ID No. 2808, Seq. ID No. 2810, Seq. ID No. 2814, Seq. ID No. 2816, Seq. ID No. 2822, Seq. ID No. 2824, Seq. ID No. 2828, Seq. ID No. 2830, Seq. ID No. 2832, Seq. ID No. 2834, Seq. ID No. 2840, Seq. ID No. 2842, Seq. ID No. 2844, Seq. ID No. 2846, Seq. ID No. 2848, Seq. ID No. 2856, Seq. ID No. 2862, Seq. ID No. 2864, Seq. ID No. 2866, Seq. ID No. 2868, Seq. ID No. 2870, Seq. ID No. 2872, Seq. ID No. 2878, Seq. ID No. 2882, Seq. ID No. 2884, Seq. ID No. 2886, Seq. ID No. 2888, Seq. ID No. 2892, Seq. ID No. 2894, Seq. ID No. 2896, Seq. ID No. 2900, Seq. ID No. 2902, Seq. ID No. 2908, Seq. ID No. 2916, Seq. ID No. 2918, Seq. ID No. 2920, Seq. ID No. 2922, Seq. ID No. 2924, Seq. ID No. 2928, Seq. ID No. 2932, Seq. ID No. 2934, Seq. ID No. 2936, Seq. ID No. 2944, Seq. ID No. 2946, Seq. ID No. 2952, Seq. ID No. 2954, Seq. ID No. 2958, Seq. ID No. 2960, Seq. ID No. 2962, Seq. ID No. 2964, Seq. ID No. 2966, Seq. ID No. 2968, Seq. ID No. 2972, Seq. ID No. 2974, Seq. ID No. 2976, Seq. ID No. 2978, Seq. ID No. 2980, Seq. ID No. 2984, Seq. ID No. 2986, Seq. ID No. 2988, Seq. ID No. 2992, Seq. ID No. 2994, Seq. ID No. 3000, Seq. ID No. 3002, Seq. ID No. 3006, Seq. ID No. 3010, Seq. ID No. 3012, Seq. ID No. 3016, Seq. ID No. 3018, Seq. ID No. 3020, Seq. ID No. 3022, Seq. ID No. 3028, Seq. ID No. 3034, Seq. ID No. 3036, Seq. ID No. 3038, Seq. ID No. 3040, Seq. ID No. 3044, Seq. ID No. 3046, Seq. ID No. 3048, Seq. ID No. 3050, Seq. ID No. 3052, Seq. ID No. 3054, Seq. ID No. 3056, Seq. ID No. 3058, Seq. ID No. 3060, Seq. ID No. 3068, Seq. ID No. 3070, Seq. ID No. 3072, Seq. ID No. 3080, Seq. ID No. 3084, Seq. ID No. 3086, Seq. ID No. 3088, Seq. ID No. 3092, Seq. ID No. 3094, Seq. ID No. 3100, Seq. ID No. 3102, Seq. ID No. 3104, Seq. ID No. 3110, Seq. ID No. 3112, Seq. ID No. 3116, Seq. ID No. 3118, Seq. ID No. 3120, Seq. ID No. 3122, Seq. ID No. 3124, Seq. ID No. 3126, Seq. ID No. 3130, Seq. ID No. 3132, Seq. ID No. 3134, Seq. ID No. 3136, Seq. 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ID No. 4950, Seq. ID No. 4952, Seq. ID No. 4954, Seq. ID No. 4958, Seq. ID No. 4960, Seq. ID No. 4962, Seq. ID No. 4964, Seq. ID No. 4974, Seq. ID No. 4976, Seq. ID No. 4978, Seq. ID No. 4980, Seq. ID No. 4982, Seq. ID No. 4984, Seq. ID No. 4986, Seq. ID No. 4988, Seq. ID No. 4990, Seq. ID No. 4992, Seq. ID No. 4994, Seq. ID No. 4996, Seq. ID No. 4998, Seq. ID No. 5000, Seq. ID No. 5004, Seq. ID No. 5006, Seq. ID No. 5008, Seq. ID No. 5010, Seq. ID No. 5012, Seq. ID No. 5014, Seq. ID No. 5018, Seq. ID No. 5020, Seq. ID No. 5022, Seq. ID No. 5024, Seq. ID No. 5026, Seq. ID No. 5030, Seq. ID No. 5032, Seq. ID No. 5034, Seq. ID No. 5036, Seq. ID No. 5042, Seq. ID No. 5044, Seq. ID No. 5046, Seq. ID No. 5048, Seq. ID No. 5058, Seq. ID No. 5060, Seq. ID No. 5064, Seq. ID No. 5066, Seq. ID No. 5068, Seq. ID No. 5070, Seq. ID No. 5076, Seq. ID No. 5078, Seq. ID No. 5080, Seq. ID No. 5082, Seq. ID No. 5084, Seq. ID No. 5086, Seq. ID No. 5088, Seq. ID No. 5092, Seq. ID No. 5100, Seq. ID No. 5102, Seq. ID No. 5104, Seq. ID No. 5110, Seq. ID No. 5112, Seq. ID No. 5114, Seq. ID No. 5116, Seq. ID No. 5118, Seq. ID No. 5122, Seq. ID No. 5126, Seq. ID No. 5128, Seq. ID No. 5134, Seq. ID No. 5140, Seq. ID No. 5142, Seq. ID No. 5146, Seq. ID No. 5148, Seq. ID No. 5150, Seq. ID No. 5152, Seq. ID No. 5156, Seq. ID No. 5158, Seq. ID No. 5160, Seq. ID No. 5162, Seq. ID No. 5166, Seq. ID No. 5168, Seq. ID No. 5170, Seq. ID No. 5178, Seq. ID No. 5182, Seq. ID No. 5184, Seq. ID No. 5186, Seq. ID No. 5188, Seq. ID No. 5190, Seq. ID No. 5192, Seq. ID No. 5194, Seq. ID No. 5196, Seq. ID No. 5198, Seq. ID No. 5200, Seq. ID No. 5202, Seq. ID No. 5204, Seq. ID No. 5206, Seq. ID No. 5210, Seq. ID No. 5212, Seq. ID No. 5216, Seq. ID No. 5220, Seq. ID No. 5222, Seq. ID No. 5230, Seq. ID No. 5232, Seq. ID No. 5240, Seq. ID No. 5242, Seq. ID No. 5244, Seq. ID No. 5246, Seq. ID No. 5252, Seq. ID No. 5254, Seq. ID No. 5256, Seq. ID No. 5262, Seq. ID No. 5264, Seq. ID No. 5266, Seq. ID No. 5268, Seq. ID No. 5278, Seq. ID No. 5280, Seq. ID No. 5282, Seq. ID No. 5286, Seq. ID No. 5288, Seq. ID No. 5292, Seq. ID No. 5296, Seq. ID No. 5298, Seq. ID No. 5300, Seq. ID No. 5302, Seq. ID No. 5304, Seq. ID No. 5306, Seq. ID No. 5308, Seq. ID No. 5310, Seq. ID No. 5312, Seq. ID No. 5314, Seq. ID No. 5318, Seq. ID No. 5320, Seq. ID No. 5322, Seq. ID No. 5324, Seq. ID No. 5328, Seq. ID No. 5330, Seq. ID No. 5332, Seq. ID No. 5334, Seq. ID No. 5336, Seq. ID No. 5338, Seq. ID No. 5344, Seq. ID No. 5346, Seq. ID No. 5350, Seq. ID No. 5352, Seq. ID No. 5358, Seq. ID No. 5360, Seq. ID No. 5366, Seq. ID No. 5368, Seq. ID No. 5374, Seq. ID No. 5378, Seq. ID No. 5380, Seq. ID No. 5382, Seq. ID No. 5384, Seq. ID No. 5388, Seq. ID No. 5390, Seq. ID No. 5392, Seq. ID No. 5394, Seq. ID No. 5398, Seq. ID No. 5400, Seq. ID No. 5402, Seq. ID No. 5404, Seq. ID No. 5406, Seq. ID No. 5408, Seq. ID No. 5410, Seq. ID No. 5412, Seq. ID No. 5416, Seq. ID No. 5418, Seq. ID No. 5420, Seq. ID No. 5422, Seq. ID No. 5424, Seq. ID No. 5426, Seq. ID No. 5428, Seq. ID No. 5432, Seq. ID No. 5434, Seq. ID No. 5436, Seq. ID No. 5438, Seq. ID No. 5440, Seq. ID No. 5442, Seq. ID No. 5444, Seq. ID No. 5448, Seq. ID No. 5450, Seq. ID No. 5452, Seq. ID No. 5454, Seq. ID No. 5456, Seq. ID No. 5458, Seq. ID No. 5468, Seq. ID No. 5472, Seq. ID No. 5474, Seq. ID No. 5478, Seq. ID No. 5480, Seq. ID No. 5482, Seq. ID No. 5492, Seq. ID No. 5494, Seq. ID No. 5496, Seq. ID No. 5500, Seq. ID No. 5504, Seq. ID No. 5510, Seq. ID No. 5514, Seq. ID No. 5516, Seq. ID No. 5518, Seq. ID No. 5520, Seq. ID No. 5522, Seq. ID No. 5528, Seq. ID No. 5530, Seq. ID No. 5532, Seq. ID No. 5534, Seq. ID No. 5538, Seq. ID No. 5540, Seq. ID No. 5542, Seq. ID No. 5544, Seq. ID No. 5546, Seq. ID No. 5548, Seq. ID No. 5550, Seq. ID No. 5552, Seq. ID No. 5554, Seq. ID No. 5558, Seq. ID No. 5560, Seq. ID No. 5564, Seq. ID No. 5568, Seq. ID No. 5570, Seq. ID No. 5576, Seq. ID No. 5578, Seq. ID No. 5582, Seq. ID No. 5584, Seq. ID No. 5586, Seq. ID No. 5590, Seq. ID No. 5592, Seq. ID No. 5594, Seq. ID No. 5596, Seq. ID No. 5600, Seq. ID No. 5602, Seq. ID No. 5608, Seq. ID No. 5614, Seq. ID No. 5616, Seq. ID No. 5618, Seq. ID No. 5620, Seq. ID No. 5622, Seq. ID No. 5626, Seq. ID No. 5628, Seq. ID No. 5630, Seq. ID No. 5632, Seq. ID No. 5638, Seq. ID No. 5640, Seq. ID No. 5642, Seq. ID No. 5646, Seq. ID No. 5648, Seq. ID No. 5650, Seq. ID No. 5652, Seq. ID No. 5656, Seq. ID No. 5658, Seq. ID No. 5662, Seq. ID No. 5666, Seq. ID No. 5668, Seq. ID No. 5670, Seq. ID No. 5678, Seq. ID No. 5680, Seq. ID No. 5684, Seq. ID No. 5686, Seq. ID No. 5688, Seq. ID No. 5690, Seq. ID No. 5692, Seq. ID No. 5694, Seq. ID No. 5698, Seq. ID No. 5700, Seq. ID No. 5702, Seq. ID No. 5704, Seq. ID No. 5706, Seq. ID No. 5708, Seq. ID No. 5712, Seq. ID No. 5714, Seq. ID No. 5716, Seq. ID No. 5718, Seq. ID No. 5720, Seq. ID No. 5722, Seq. ID No. 5724, Seq. ID No. 5726, Seq. ID No. 5728, Seq. ID No. 5736, Seq. ID No. 5740, Seq. ID No. 5742, Seq. ID No. 5744, Seq. ID No. 5746, Seq. ID No. 5748, Seq. ID No. 5750, Seq. ID No. 5752, Seq. ID No. 5754, Seq. ID No. 5756, Seq. ID No. 5758, Seq. ID No. 5760, Seq. ID No. 5762, Seq. ID No. 5770, Seq. ID No. 5772, Seq. ID No. 5778, Seq. ID No. 5780, Seq. ID No. 5784, Seq. ID No. 5788, Seq. ID No. 5792, Seq. ID No. 5796, Seq. ID No. 5800, Seq. ID No. 5802, Seq. ID No. 5808, Seq. ID No. 5810, Seq. ID No. 5814, Seq. ID No. 5816, Seq. ID No. 5820, Seq. ID No. 5822, Seq. ID No. 5824, Seq. ID No. 5826, Seq. ID No. 5828, Seq. ID No. 5830, Seq. ID No. 5832, Seq. ID No. 5834, Seq. ID No. 5836, Seq. ID No. 5838, Seq. ID No. 5840, Seq. ID No. 5842, Seq. ID No. 5846, Seq. ID No. 5848, Seq. ID No. 5850, Seq. ID No. 5852, Seq. ID No. 5856, Seq. ID No. 5858, Seq. ID No. 5860, Seq. ID No. 5862, Seq. ID No. 5864, Seq. ID No. 5866, Seq. ID No. 5870, Seq. ID No. 5872, Seq. ID No. 5874, Seq. ID No. 5876, Seq. ID No. 5880, Seq. ID No. 5882, Seq. ID No. 5884, Seq. ID No. 5890, Seq. ID No. 5896, Seq. ID No. 5898, Seq. ID No. 5902, Seq. ID No. 5904, Seq. ID No. 5912, Seq. ID No. 5914, Seq. ID No. 5916, Seq. ID No. 5918, Seq. ID No. 5920, Seq. ID No. 5928, Seq. ID No. 5930, Seq. ID No. 5934, Seq. ID No. 5936, Seq. ID No. 5938, Seq. ID No. 5942, Seq. ID No. 5946, Seq. ID No. 5948, Seq. ID No. 5952, Seq. ID No. 5960, Seq. ID No. 5962, Seq. ID No. 5964, Seq. ID No. 5966, Seq. ID No. 5968, Seq. ID No. 5970, Seq. ID No. 5972, Seq. ID No. 5974, Seq. ID No. 5978, Seq. ID No. 5980, Seq. ID No. 5982, Seq. ID No. 5986, Seq. ID No. 5988, Seq. ID No. 5990, Seq. ID No. 5992, Seq. ID No. 5994, Seq. ID No. 5996, Seq. ID No. 6000, Seq. ID No. 6002, Seq. ID No. 6004, Seq. ID No. 6010, Seq. ID No. 6012, Seq. ID No. 6014, Seq. ID No. 6016, Seq. ID No. 6018, Seq. ID No. 6026, Seq. ID No. 6028, Seq. ID No. 6030, Seq. ID No. 6032, Seq. ID No. 6034, Seq. ID No. 6036, Seq. ID No. 6040, Seq. ID No. 6042, Seq. ID No. 6044, Seq. ID No. 6046, Seq. ID No. 6050, Seq. ID No. 6052, Seq. ID No. 6054, Seq. ID No. 6056, Seq. ID No. 6058, Seq. ID No. 6062, Seq. ID No. 6064, Seq. ID No. 6066, Seq. ID No. 6070, Seq. ID No. 6072, Seq. ID No. 6074, Seq. ID No. 6078, Seq. ID No. 6080, Seq. ID No. 6086, Seq. ID No. 6088, Seq. ID No. 6090, Seq. ID No. 6094, Seq. ID No. 6096, Seq. ID No. 6102, Seq. ID No. 6104, Seq. ID No. 6110, Seq. ID No. 6112, Seq. ID No. 6118, Seq. ID No. 6122, Seq. ID No. 6124, Seq. ID No. 6130, Seq. ID No. 6132, Seq. ID No. 6134, Seq. ID No. 6136, Seq. ID No. 6138, Seq. ID No. 6140, Seq. ID No. 6142, Seq. ID No. 6146, Seq. ID No. 6152, Seq. ID No. 6156, Seq. ID No. 6158, Seq. ID No. 6160, Seq. ID No. 6166, Seq. ID No. 6168, Seq. ID No. 6170, Seq. ID No. 6172, Seq. ID No. 6176, Seq. ID No. 6178, Seq. ID No. 6182, Seq. ID No. 6188, Seq. ID No. 6194, Seq. ID No. 6196, Seq. ID No. 6198, Seq. ID No. 6200, Seq. ID No. 6202, Seq. ID No. 6210, Seq. ID No. 6214, Seq. ID No. 6216, Seq. ID No. 6218, Seq. ID No. 6220, Seq. ID No. 6232, Seq. ID No. 6234, Seq. ID No. 6236, Seq. ID No. 6240, Seq. ID No. 6242, Seq. ID No. 6244, Seq. ID No. 6250, Seq. ID No. 6258, Seq. ID No. 6260, Seq. ID No. 6262, Seq. ID No. 6264, Seq. ID No. 6268, Seq. ID No. 6270, Seq. ID No. 6272, Seq. ID No. 6276, Seq. ID No. 6278, Seq. ID No. 6280, Seq. ID No. 6282, Seq. ID No. 6284, Seq. ID No. 6286, Seq. ID No. 6288, Seq. ID No. 6294, Seq. ID No. 6296, Seq. ID No. 6298, Seq. ID No. 6300, Seq. ID No. 6306, Seq. ID No. 6310, Seq. ID No. 6312, Seq. ID No. 6316, Seq. ID No. 6318, Seq. ID No. 6320, Seq. ID No. 6322, Seq. ID No. 6324, Seq. ID No. 6326, Seq. ID No. 6328, Seq. ID No. 6330, Seq. ID No. 6332, Seq. ID No. 6336, Seq. ID No. 6338, Seq. ID No. 6342, Seq. ID No. 6346, Seq. ID No. 6350, Seq. ID No. 6352, Seq. ID No. 6354, Seq. ID No. 6360, Seq. ID No. 6362, Seq. ID No. 6368, Seq. ID No. 6370, Seq. ID No. 6372, Seq. ID No. 6374, Seq. ID No. 6376, Seq. ID No. 6378, Seq. ID No. 6380, Seq. ID No. 6382, Seq. ID No. 6386, Seq. ID No. 6390, Seq. ID No. 6394, Seq. ID No. 6396, Seq. ID No. 6400, Seq. ID No. 6410, Seq. ID No. 6412, Seq. ID No. 6414, Seq. ID No. 6418, Seq. ID No. 6422, Seq. ID No. 6424, Seq. ID No. 6426, Seq. ID No. 6428, Seq. ID No. 6430, Seq. ID No. 6432, Seq. ID No. 6442, Seq. ID No. 6444, Seq. ID No. 6446, Seq. ID No. 6452, Seq. ID No. 6454, Seq. ID No. 6460, Seq. ID No. 6462, Seq. ID No. 6464, Seq. ID No. 6466, Seq. ID No. 6468, Seq. ID No. 6470, Seq. ID No. 6472, Seq. ID No. 6474, Seq. ID No. 6480, Seq. ID No. 6484, Seq. ID No. 6494, Seq. ID No. 6496, Seq. ID No. 6498, Seq. ID No. 6502, Seq. ID No. 6504, Seq. ID No. 6506, Seq. ID No. 6508, Seq. ID No. 6512, Seq. ID No. 6518, Seq. ID No. 6524, Seq. ID No. 6526, Seq. ID No. 6536, Seq. ID No. 6538, Seq. ID No. 6540, Seq. ID No. 6542, Seq. ID No. 6544, Seq. ID No. 6546, Seq. ID No. 6548, Seq. ID No. 6550, Seq. ID No. 6552, Seq. ID No. 6554, Seq. ID No. 6556, Seq. ID No. 6558, Seq. ID No. 6560, Seq. ID No. 6564, Seq. ID No. 6574, Seq. ID No. 6576, Seq. ID No. 6578, Seq. ID No. 6580, Seq. ID No. 6584, Seq. ID No. 6586, Seq. ID No. 6588, Seq. ID No. 6592, Seq. ID No. 6598, Seq. ID No. 6602, Seq. ID No. 6604, Seq. ID No. 6606, Seq. ID No. 6610, Seq. ID No. 6612, Seq. ID No. 6614, Seq. ID No. 6616, Seq. ID No. 6618, Seq. ID No. 6620, Seq. ID No. 6622, Seq. ID No. 6624, Seq. ID No. 6628, Seq. ID No. 6630, Seq. ID No. 6632, Seq. ID No. 6634, Seq. ID No. 6638, Seq. ID No. 6640, Seq. ID No. 6644, Seq. ID No. 6646, and Seq. ID No. 6650.

In yet another preferred embodiment, the polypeptide is selected from the Alloiococcus otitidis polypeptides identified by the Applicants' assignee's ORF finder program that searches for a transmembrane domain between two Stop codons and a Start codon immediately upstream of this transmembrane region, and is selected from one of Seq. ID No. 8, Seq. ID No. 10, Seq. ID No. 34, Seq. ID No. 48, Seq. ID No. 68, Seq. ID No. 86, Seq. ID No. 88, Seq. ID No. 124, Seq. ID No. 134, Seq. ID No. 142, Seq. ID No. 160, Seq. ID No. 164, Seq. ID No. 192, Seq. ID No. 210, Seq. ID No. 212, Seq. ID No. 216, Seq. ID No. 218, Seq. ID No. 226, Seq. ID No. 236, Seq. ID No. 238, Seq. ID No. 250, Seq. ID No. 252, Seq. ID No. 256, Seq. ID No. 272, Seq. ID No. 278, Seq. ID No. 286, Seq. ID No. 288, Seq. ID No. 290, Seq. ID No. 328, Seq. ID No. 330, Seq. ID No. 374, Seq. ID No. 376, Seq. ID No. 420, Seq. ID No. 488, Seq. ID No. 498, Seq. ID No. 500, Seq. ID No. 504, Seq. ID No. 506, Seq. ID No. 510, Seq. ID No. 512, Seq. ID No. 516, Seq. ID No. 526, Seq. ID No. 528, Seq. ID No. 546, Seq. ID No. 568, Seq. ID No. 570, Seq. ID No. 576, Seq. ID No. 578, Seq. ID No. 580, Seq. ID No. 594, Seq. ID No. 618, Seq. ID No. 638, Seq. ID No. 640, Seq. ID No. 642, Seq. ID No. 646, Seq. ID No. 654, Seq. ID No. 656, Seq. ID No. 660, Seq. ID No. 670, Seq. ID No. 676, Seq. ID No. 678, Seq. ID No. 680, Seq. ID No. 716, Seq. ID No. 718, Seq. ID No. 720, Seq. ID No. 722, Seq. ID No. 724, Seq. ID No. 748, Seq. ID No. 752, Seq. ID No. 756, Seq. ID No. 758, Seq. ID No. 760, Seq. ID No. 762, Seq. ID No. 764, Seq. ID No. 770, Seq. ID No. 778, Seq. ID No. 780, Seq. ID No. 808, Seq. ID No. 810, Seq. ID No. 820, Seq. ID No. 826, Seq. ID No. 864, Seq. ID No. 894, Seq. ID No. 902, Seq. ID No. 936, Seq. ID No. 944, Seq. ID No. 956, Seq. ID No. 968, Seq. ID No. 980, Seq. ID No. 1006, Seq. ID No. 1010, Seq. ID No. 1012, Seq. ID No. 1014, Seq. ID No. 1016, Seq. ID No. 1020, Seq. ID No. 1030, Seq. ID No. 1032, Seq. ID No. 1034, Seq. ID No. 1038, Seq. ID No. 1040, Seq. ID No. 1046, Seq. ID No. 1056, Seq. ID No. 1076, Seq. ID No. 1106, Seq. ID No. 1132, Seq. ID No. 1136, Seq. ID No. 1138, Seq. ID No. 1166, Seq. ID No. 1168, Seq. ID No. 1170, Seq. ID No. 1184, Seq. ID No. 1194, Seq. ID No. 1198, Seq. ID No. 1214, Seq. ID No. 1224, Seq. ID No. 1228, Seq. ID No. 1230, Seq. ID No. 1238, Seq. ID No. 1244, Seq. ID No. 1266, Seq. ID No. 1268, Seq. ID No. 1270, Seq. ID No. 1272, Seq. ID No. 1284, Seq. ID No. 1288, Seq. ID No. 1292, Seq. ID No. 1298, Seq. ID No. 1306, Seq. ID No. 1316, Seq. ID No. 1326, Seq. ID No. 1328, Seq. ID No. 1330, Seq. ID No. 1332, Seq. ID No. 1342, Seq. ID No. 1354, Seq. ID No. 1368, Seq. ID No. 1402, Seq. ID No. 1430, Seq. ID No. 1436, Seq. ID No. 1446, Seq. ID No. 1482, Seq. ID No. 1514, Seq. ID No. 1516, Seq. ID No. 1518, Seq. ID No. 1530, Seq. ID No. 1534, Seq. ID No. 1536, Seq. ID No. 1546, Seq. ID No. 1548, Seq. ID No. 1552, Seq. ID No. 1560, Seq. ID No. 1564, Seq. ID No. 1572, Seq. ID No. 1580, Seq. ID No. 1584, Seq. ID No. 1586, Seq. ID No. 1622, Seq. ID No. 1634, Seq. ID No. 1644, Seq. ID No. 1646, Seq. ID No. 1648, Seq. ID No. 1650, Seq. ID No. 1654, Seq. ID No. 1672, Seq. ID No. 1674, Seq. ID No. 1678, Seq. ID No. 1682, Seq. ID No. 1708, Seq. ID No. 1732, Seq. ID No. 1734, Seq. ID No. 1738, Seq. ID No. 1754, Seq. ID No. 1758, Seq. ID No. 1766, Seq. ID No. 1768, Seq. ID No. 1788, Seq. ID No. 1792, Seq. ID No. 1798, Seq. ID No. 1806, Seq. ID No. 1820, Seq. ID No. 1822, Seq. ID No. 1824, Seq. ID No. 1840, Seq. ID No. 1870, Seq. ID No. 1876, Seq. ID No. 1892, Seq. ID No. 1894, Seq. ID No. 1896, Seq. ID No. 1924, Seq. ID No. 1928, Seq. ID No. 1970, Seq. ID No. 1982, Seq. ID No. 1992, Seq. ID No. 1994, Seq. ID No. 2014, Seq. ID No. 2018, Seq. ID No. 2028, Seq. ID No. 2034, Seq. ID No. 2042, Seq. ID No. 2050, Seq. ID No. 2054, Seq. ID No. 2088, Seq. ID No. 2090, Seq. ID No. 2106, Seq. ID No. 2116, Seq. ID No. 2122, Seq. ID No. 2128, Seq. ID No. 2152, Seq. ID No. 2160, Seq. ID No. 2172, Seq. ID No. 2174, Seq. ID No. 2178, Seq. ID No. 2188, Seq. ID No. 2238, Seq. ID No. 2240, Seq. ID No. 2246, Seq. ID No. 2250, Seq. ID No. 2272, Seq. ID No. 2284, Seq. ID No. 2290, Seq. ID No. 2292, Seq. ID No. 2294, Seq. ID No. 2296, Seq. ID No. 2304, Seq. ID No. 2306, Seq. ID No. 2308, Seq. ID No. 2318, Seq. ID No. 2320, Seq. ID No. 2322, Seq. ID No. 2324, Seq. ID No. 2326, Seq. ID No. 2328, Seq. ID No. 2334, Seq. ID No. 2344, Seq. ID No. 2348, Seq. ID No. 2350, Seq. ID No. 2352, Seq. ID No. 2354, Seq. ID No. 2356, Seq. ID No. 2358, Seq. ID No. 2366, Seq. ID No. 2390, Seq. ID No. 2392, Seq. ID No. 2408, Seq. ID No. 2420, Seq. ID No. 2422, Seq. ID No. 2428, Seq. ID No. 2430, Seq. ID No. 2434, Seq. ID No. 2450, Seq. ID No. 2460, Seq. ID No. 2490, Seq. ID No. 2498, Seq. ID No. 2504, Seq. ID No. 2508, Seq. ID No. 2516, Seq. ID No. 2524, Seq. ID No. 2526, Seq. ID No. 2532, Seq. ID No. 2536, Seq. ID No. 2538, Seq. ID No. 2542, Seq. ID No. 2544, Seq. ID No. 2546, Seq. ID No. 2556, Seq. ID No. 2558, Seq. ID No. 2570, Seq. ID No. 2572, Seq. ID No. 2584, Seq. ID No. 2592, Seq. ID No. 2598, Seq. ID No. 2600, Seq. ID No. 2602, Seq. ID No. 2608, Seq. ID No. 2612, Seq. ID No. 2622, Seq. ID No. 2630, Seq. ID No. 2652, Seq. ID No. 2680, Seq. ID No. 2694, Seq. ID No. 2702, Seq. ID No. 2704, Seq. ID No. 2706, Seq. ID No. 2708, Seq. ID No. 2732, Seq. ID No. 2734, Seq. ID No. 2784, Seq. ID No. 2786, Seq. ID No. 2814, Seq. ID No. 2816, Seq. ID No. 2824, Seq. ID No. 2836, Seq. ID No. 2838, Seq. ID No. 2842, Seq. ID No. 2854, Seq. ID No. 2874, Seq. ID No. 2876, Seq. ID No. 2882, Seq. ID-No. 2906, Seq. ID No. 2936, Seq. ID No. 2938, Seq. ID No. 2940, Seq. ID No. 2942, Seq. ID No. 2948, Seq. ID No. 2950, Seq. ID No. 2970, Seq. ID No. 2974, Seq. ID No. 2978, Seq. ID No. 2982, Seq. ID No. 2988, Seq. ID No. 2992, Seq. ID No. 2996, Seq. ID No. 2998, Seq. ID No. 3006, Seq. ID No. 3008, Seq. ID No. 3014, Seq. ID No. 3024, Seq. ID No. 3026, Seq. ID No. 3028, Seq. ID No. 3030, Seq. ID No. 3032, Seq. ID No. 3044, Seq. ID No. 3056, Seq. ID No. 3064, Seq. ID No. 3072, Seq. ID No. 3074, Seq. ID No. 3076, Seq. ID No. 3078, Seq. ID No. 3124, Seq. ID No. 3146, Seq. ID No. 3156, Seq. ID No. 3158, Seq. ID No. 3164, Seq. ID No. 3184, Seq. ID No. 3194, Seq. ID No. 3202, Seq. ID No. 3214, Seq. ID No. 3216, Seq. ID No. 3218, Seq. ID No. 3220, Seq. ID No. 3242, Seq. ID No. 3244, Seq. ID No. 3246, Seq. ID No. 3250, Seq. ID No. 3258, Seq. ID No. 3262, Seq. ID No. 3270, Seq. ID No. 3276, Seq. ID No. 3298, Seq. ID No. 3318, Seq. ID No. 3324, Seq. ID No. 3338, Seq. ID No. 3340, Seq. ID No. 3350, Seq. ID No. 3352, Seq. ID No. 3354, Seq. ID No. 3358, Seq. ID No. 3360, Seq. ID No. 3378, Seq. ID No. 3390, Seq. ID No. 3392, Seq. ID No. 3396, Seq. ID No. 3406, Seq. ID No. 3422, Seq. ID No. 3426, Seq. ID No. 3450, Seq. ID No. 3452, Seq. ID No. 3454, Seq. ID No. 3456, Seq. ID No. 3458, Seq. ID No. 3464, Seq. ID No. 3482, Seq. ID No. 3492, Seq. ID No. 3494, Seq. ID No. 3504, Seq. ID No. 3506, Seq. ID No. 3528, Seq. ID No. 3594, Seq. ID No. 3596, Seq. ID No. 3622, Seq. ID No. 3626, Seq. ID No. 3636, Seq. ID No. 3680, Seq. ID No. 3724, Seq. ID No. 3728, Seq. ID No. 3746, Seq. ID No. 3754, Seq. ID No. 3756, Seq. ID No. 3758, Seq. ID No. 3762, Seq. ID No. 3764, Seq. ID No. 3766, Seq. ID No. 3784, Seq. ID No. 3794, Seq. ID No. 3800, Seq. ID No. 3814, Seq. ID No. 3838, Seq. ID No. 3840, Seq. ID No. 3850, Seq. ID No. 3852, Seq. ID No. 3854, Seq. ID No. 3860, Seq. ID No. 3862, Seq. ID No. 3864, Seq. ID No. 3866, Seq. ID No. 3880, Seq. ID No. 3890, Seq. ID No. 3892, Seq. ID No. 3904, Seq. ID No. 3926, Seq. ID No. 3964, Seq. ID No. 3974, Seq. ID No. 3976, Seq. ID No. 4006, Seq. ID No. 4026, Seq. ID No. 4028, Seq. ID No. 4040, Seq. ID No. 4042, Seq. ID No. 4044, Seq. ID No. 4046, Seq. ID No. 4048, Seq. ID No. 4062, Seq. ID No. 4072, Seq. ID No. 4074, Seq. ID No. 4080, Seq. ID No. 4082, Seq. ID No. 4084, Seq. ID No. 4102, Seq. ID No. 4104, Seq. ID No. 4112, Seq. ID No. 4134, Seq. ID No. 4138, Seq. ID No. 4140, Seq. ID No. 4146, Seq. ID No. 4152, Seq. ID No. 4222, Seq. ID No. 4224, Seq. ID No. 4226, Seq. ID No. 4228, Seq. ID No. 4232, Seq. ID No. 4242, Seq. ID No. 4248, Seq. ID No. 4254, Seq. ID No. 4258, Seq. ID No. 4262, Seq. ID No. 4308, Seq. ID No. 4312, Seq. ID No. 4314, Seq. ID No. 4344, Seq. ID No. 4380, Seq. ID No. 4386, Seq. ID No. 4390, Seq. ID No. 4440, Seq. ID No. 4470, Seq. ID No. 4474, Seq. ID No. 4482, Seq. ID No. 4484, Seq. ID No. 4486, Seq. ID No. 4498, Seq. ID No. 4516, Seq. ID No. 4534, Seq. ID No. 4588, Seq. ID No. 4640, Seq. ID No. 4644, Seq. ID No. 4682, Seq. ID No. 4706, Seq. ID No. 4708, Seq. ID No. 4710, Seq. ID No. 4712, Seq. ID No. 4716, Seq. ID No. 4718, Seq. ID No. 4738, Seq. ID No. 4760, Seq. ID No. 4814, Seq. ID No. 4828, Seq. ID No. 4870, Seq. ID No. 4872, Seq. ID No. 4874, Seq. ID No. 4876, Seq. ID No. 4920, Seq. ID No. 4932, Seq. ID No. 4950, Seq. ID No. 4952, Seq. ID No. 4988, Seq. ID No. 5032, Seq. ID No. 5062, Seq. ID No. 5086, Seq. ID No. 5104, Seq. ID No. 5124, Seq. ID No. 5130, Seq. ID No. 5132, Seq. ID No. 5136, Seq. ID No. 5138, Seq. ID No. 5142, Seq. ID No. 5166, Seq. ID No. 5176, Seq. ID No. 5200, Seq. ID No. 5206, Seq. ID No. 5208, Seq. ID No. 5214, Seq. ID No. 5220, Seq. ID No. 5224, Seq. ID No. 5268, Seq. ID No. 5282, Seq. ID No. 5386, Seq. ID No. 5388, Seq. ID No. 5414, Seq. ID No. 5416, Seq. ID No. 5434, Seq. ID No. 5454, Seq. ID No. 5460, Seq. ID No. 5462, Seq. ID No. 5464, Seq. ID No. 5466, Seq. ID No. 5492, Seq. ID No. 5498, Seq. ID No. 5510, Seq. ID No. 5514, Seq. ID No. 5526, Seq. ID No. 5532, Seq. ID No. 5570, Seq. ID No. 5588, Seq. ID No. 5596, Seq. ID No. 5598, Seq. ID No. 5610, Seq. ID No. 5612, Seq. ID No. 5622, Seq. ID No. 5624, Seq. ID No. 5634, Seq. ID No. 5638, Seq. ID No. 5644, Seq. ID No. 5650, Seq. ID No. 5660, Seq. ID No. 5684, Seq. ID No. 5686, Seq. ID No. 5700, Seq. ID No. 5706, Seq. ID No. 5710, Seq. ID No. 5730, Seq. ID No. 5734, Seq. ID No. 5764, Seq. ID No. 5766, Seq. ID No. 5768, Seq. ID No. 5772, Seq. ID No. 5784, Seq. ID No. 5792, Seq. ID No. 5798, Seq. ID No. 5886, Seq. ID No. 5890, Seq. ID No. 5894, Seq. ID No. 5896, Seq. ID No. 5900, Seq. ID No. 5902, Seq. ID No. 5906, Seq. ID No. 5910, Seq. ID No. 5922, Seq. ID No. 5924, Seq. ID No. 5928, Seq. ID No. 5940, Seq. ID No. 6028, Seq. ID No. 6044, Seq. ID No. 6048, Seq. ID No. 6060, Seq. ID No. 6068, Seq. ID No. 6090, Seq. ID No. 6092, Seq. ID No. 6108, Seq. ID No. 6112, Seq. ID No. 6118, Seq. ID No. 6162, Seq. ID No. 6164, Seq. ID No. 6166, Seq. ID No. 6170, Seq. ID No. 6184, Seq. ID No. 6186, Seq. ID No. 6190, Seq. ID No. 6192, Seq. ID No. 6198, Seq. ID No. 6204, Seq. ID No. 6206, Seq. ID No. 6210, Seq. ID No. 6222, Seq. ID No. 6224, Seq. ID No. 6226, Seq. ID No. 6228, Seq. ID No. 6230, Seq. ID No. 6236, Seq. ID No. 6238, Seq. ID No. 6244, Seq. ID No. 6246, Seq. ID No. 6250, Seq. ID No. 6254, Seq. ID No. 6264, Seq. ID No. 6266, Seq. ID No. 6274, Seq. ID No. 6276, Seq. ID No. 6286, Seq. ID No. 6290, Seq. ID No. 6302, Seq. ID No. 6304, Seq. ID No. 6364, Seq. ID No. 6378, Seq. ID No. 6382, Seq. ID No. 6384, Seq. ID No. 6416, Seq. ID No. 6428, Seq. ID No. 6432, Seq. ID No. 6474, Seq. ID No. 6498, Seq. ID No. 6572, Seq. ID No. 6582, Seq. ID No. 6594, Seq. ID No. 6600, Seq. ID No. 6632, and Seq. ID No. 6640.

In another aspect of the invention, the polypeptides are expressed and purified in a recombinant expression system. Thus, in certain embodiments, the invention provides a recombinant expression vector comprising a nucleotide sequence having at least about 70% identity to a nucleotide sequence chosen from one of odd numbered sequences set out in SEQ ID NO: 1 through SEQ ID NO: 6649, a complement thereof, a degenerate variant thereof, or a fragment thereof.

In certain other embodiments, the polynucleotide is selected from the group consisting of genomic DNA, cDNA, and RNA. In another embodiment, the polynucleotide comprised within the vector further comprises heterologous nucleotide sequences.

In other embodiments, the polynucleotide is operatively linked to one or more gene expression regulatory elements. In yet other embodiments, the polynucleotide encodes a polypeptide comprising an amino acid sequence having at least about 70% identity to an amino acid sequence chosen from one of even numbered sequences set out in SEQ ID NO: 2 through SEQ ID NO: 6650, a complement thereof, a biological equivalent thereof, or a fragment thereof. In a preferred embodiment, the vector is a plasmid.

In another aspect of the invention, provided is a genetically engineered host cell, transfected, transformed or infected with a recombinant expression vector comprising a nucleotide sequence having at least about 70% identity to a nucleotide sequence chosen from one of odd numbered sequences set out in SEQ ID NO: 1 through SEQ ID NO: 6649, a complement thereof, a degenerate variant thereof, or a fragment thereof. In a preferred embodiment, the host cell is a bacterial cell. In a further embodiment, the polynucleotide is expressed to produce the encoded polypeptide, a complement thereof, a biological equivalent thereof, or a fragment thereof.

In another aspect of the invention, the polypeptides are expressed and purified in a recombinant expression system. Thus, in certain embodiments, the invention provides a recombinant expression vector comprising a nucleotide sequence having at least about 70% identity to a nucleotide sequence chosen from one of odd numbered sequences set out in SEQ ID NO: 1 through SEQ ID NO: 6649, a complement thereof, a degenerate variant thereof, or a fragment thereof. In certain other embodiments, the polynucleotide is selected from the group consisting of genomic DNA, cDNA, and RNA. In another embodiment, the polynucleotide comprised within the vector further comprises heterologous nucleotide sequences.

In other embodiments, the present invention provides an antibody specific for an Alloiococcus otitidis polynucleotide chosen from one of odd numbered sequences set out in SEQ ID NO: 1 through SEQ ID NO: 6649, a fragment thereof, a degenerate variant thereof, or an antibody specific for an Alloiococcus otitidis polypeptide chosen from one of even numbered sequences set out in SEQ ID NO: 2 through SEQ ID NO: 6650, a biological equivalent thereof, or a fragment thereof. In certain embodiments, the antibody is selected from the group consisting of monoclonal, polyclonal, chimeric, human, humanized and single chain. In a preferred embodiment, the antibody is monoclonal. In another preferred embodiment, the antibody is humanized.

The present invention further provides pharmaceutical compositions, in particular immunogenic compositions, for the prevention and/or treatment of bacterial infection. Thus, in one embodiment an immunogenic composition is provided comprising one or more polypeptides having an amino acid sequence chosen from one or more of even numbered sequences set out in SEQ ID NO: 2 through SEQ ID NO: 6650, a biological equivalent thereof, or a fragment thereof. In certain embodiments, the composition further comprises a pharmaceutically acceptable carrier. In yet other embodiments, the immunogenic composition further comprises one or more adjuvants. In preferred embodiments the polypeptide of the invention is further defined as: (a) an Alloiococcus otitidis polypeptide predicted by SignalP algorithm analysis as having met all four criteria set out in the SignalP algorithm for a polypeptide having a signal peptide and a subset of these are predicted by HMM SignalP algorithm analysis as having a signal peptide; (b) an Alloiococcus otitidis polypeptide predicted by SignalP algorithm analysis as having met three of the four criteria set out in the SignalP algorithm for a polypeptide having a signal peptide and a subset of these predicted by HMM SignalP algorithm analysis as having a signal peptide; (c) an Alloiococcus otitidis polypeptide predicted by HMM SignalP algorithm analysis as having a signal peptide; (d) an Alloiococcus otitidis polypeptide predicted by HMM SignalP algorithm analysis as being a non-secretory protein; (e) an Alloiococcus otitidis polypeptide identified by Pfam analysis; (f) an Alloiococcus otitidis polypeptide identified by BlastP analysis as being secreted, surface exposed, vaccine candidate; (g) an Alloiococcus otitidis polypeptide identified using proteomics methodology as sharing homology with surface exposed proteins of Streptococcus pneumoniae; (h) an Alloiococcus otitidis polypeptide having a LPXTG motif, wherein the polypeptide is covalently attached to the peptidoglycan layer; (i) an Alloiococcus otitidis lipoprotein; (j) an Alloiococcus otitidis polypeptide non-covalently associated with the peptidoglycan layer; (k) an Alloiococcus otitidis polypeptide having an RGDX motif wherein X is not a proline residue; (l) an Alloiococcus otitidis polypeptide predicted by BlastP as being involved in capsule biosynthesis and transport; (m) an Alloiococcus otitidis polypeptide identified by BlastP as being localized within the capsule loci of the Alloiococcus otitidis genome; (n) an Alloiococcus otitidis polypeptide predicted by BlastP as being associated with sporulation; (o) an Alloiococcus otitidis polypeptide encoded by unique ORFs identified by BlastP analysis as having a BlastP ‘E Value’ of >e⁻¹⁰; (p) an Alloiococcus otitidis polypeptide identified by Glimmer™ ORF finder program; (q) an Alloiococcus otitidis polypeptide identified by GeneMark™ ORF finder program; (r) an Alloiococcus otitidis polypeptide identified by Applicants' assignee's ORF finder program that searches for an ATG, GTG or TTG Start codon between a Stop-Stop region; and (s) an Alloiococcus otitidis polypeptide identified by Applicants' assignee's ORF finder program that searches for a transmembrane domain between two Stop codons and a Start codon immediately upstream of this transmembrane region.

In one preferred embodiment,the invention comprises an isolated polypeptide encoded by a polynucleotide contained-within the Alloiococcus otitidis genomic sequence, wherein the polynucleotide comprises a nucleotide sequence having at least about 70% identity to a nucleotide sequence contained within SEQ ID NO: 6651, a complement thereof, a degenerate variant thereof, and a fragment thereof.

In certain other embodiments, the immunogenic composition further comprises heterologous amino acids. In particular embodiments, the polypeptide is a fusion polypeptide.

In further embodiments, provided is an immunogenic composition comprising a polynucleotide having a nucleotide sequence chosen from one of odd numbered sequences listed in SEQ ID NO: 1 through SEQ ID NO: 6649, a degenerate variant thereof, or a fragment thereof and is comprised in an expression vector. In preferred embodiments, the vector is plasmid DNA. In another embodiment, the polynucleotide comprises heterologous nucleotides. In still other embodiments, the polynucleotide is operatively linked to one or more gene expression regulatory elements. In yet other embodiments, the polynucleotide directs the expression of a neutralizing epitope of Alloiococcus otitidis. In preferred embodiments, the immunogenic composition further comprises one or more adjuvants.

In yet further embodiments, provided is a pharmaceutical composition comprising a polypeptide and a pharmaceutically acceptable carrier, wherein the polypeptide comprises an amino acid chosen from one of even numbered sequence listings set out in SEQ ID NO: 2 through SEQ ID NO: 6650, a complement thereof, a biological equivalent thereof, or a fragment thereof. In preferred embodiments the polypeptide of the invention is further defined as: (a) an Alloiococcus otitidis polypeptide predicted by SignalP algorithm analysis as having met all four criteria set out in the SignalP algorithm for a polypeptide having a signal peptide and a subset of these are predicted by HMM SignalP algorithm analysis as having a signal peptide; (b) an Alloiococcus otitidis polypeptide predicted by SignalP algorithm analysis as having met three of the four criteria set out in the SignalP algorithm for a polypeptide having a signal peptide and a subset of these predicted by HMM SignalP algorithm analysis as having a signal peptide; (c) an Alloiococcus otitidis polypeptide predicted by HMM SignalP algorithm analysis as having a signal peptide; (d) an Alloiococcus otitidis polypeptide predicted by HMM SignalP algorithm analysis as being a non-secretory protein; (e) an Alloiococcus otitidis polypeptide identified by Pfam analysis; (f) an Alloiococcus otitidis polypeptide identified by BlastP analysis as being secreted, surface exposed, vaccine; (g) an Alloiococcus otitidis polypeptide identified using proteomics methodology as sharing homology with surface exposed proteins of Streptococcus pneumoniae; (h) an Alloiococcus otitidis polypeptide having a LPXTG motif, wherein the polypeptide is covalently attached to the peptidoglycan layer; (i) an Alloiococcus otitidis lipoprotein; (j) an Alloiococcus otitidis polypeptide non-covalently associated with the peptidoglycan layer; (k) an Alloiococcus otitidis polypeptide having an RGDX motif wherein X is not a proline residue; (l) an Alloiococcus otitidis polypeptide predicted by BlastP as being involved in capsule biosynthesis and transport; (m) an Alloiococcus otitidis polypeptide identified by BlastP as being localized within the capsule loci of the Alloiococcus otitidis genome; (n) an Alloiococcus otitidis polypeptide predicted by BlastP as being associated with sporulation; (o) an Alloiococcus otitidis polypeptide encoded by unique ORFs identified by BlastP analysis as having a BlastP ‘E Value’ of >e⁻¹⁰; (p) an Alloiococcus otitidis polypeptide identified by Glimmer™ ORF finder program; (q)an Alloiococcus otitidis polypeptide identified by GeneMark™ ORF finder program; (r) an Alloiococcus otitidis polypeptide identified by Applicants' assignee's ORF finder program that searches for an ATG, GTG or TTG start codon between a Stop-Stop region; and (s) an Alloiococcus otitidis polypeptide identified by Applicants' assignee's ORF finder program that searches for a transmembrane domain between two Stop codons and a Start codon immediately upstream of this transmembrane region.

In another embodiment, a method of immunizing against Alloiococcus otitidis is provided comprising administering to a host an immunizing amount of an immunogenic composition comprising a polypeptide and a pharmaceutically acceptable carrier, wherein the polypeptide comprises an amino acid sequence chosen from one of even numbered sequences set forth in SEQ ID NO: 2 through SEQ ID NO: 6650, a biological equivalent thereof, or a fragment thereof. In certain embodiments, the polypeptide is a fusion polypeptide. In other embodiments, the method further comprises administering an adjuvant.

In other embodiments the polypeptides of the invention comprise heterologous amino acids. In still other embodiments, the polypeptide in the pharmaceutical composition is a fusion polypeptide.

Other embodiments of the invention provide a DNA chip comprising an array of polynucleotides, wherein at least one of the polynucleotides comprise a nucleotide sequence chosen from one of odd numbered sequences set forth in SEQ ID NO: 1 through SEQ ID NO: 6649, a complement thereof, a degenerate variant thereof, or a fragment thereof.

Also provided is a protein chip comprising an array of polypeptides, wherein at least one of the polypeptides comprises an amino acid sequence chosen from one of even numbered sequences set forth in SEQ ID NO: 2 through SEQ ID NO: 6650, a biological equivalent thereof, or a fragment thereof.

The invention further provides methods of detecting Alloiococcus otitidis polynucleotides and polypeptides as well as kits for diagnosing Alloiococcus otitidis infection. Other embodiments provide a method for the detection and/or identification of Alloiococcus otitidis in a biological sample comprising contacting the sample with an oligonucleotide probe of a polynucleotide comprising the nucleotide sequence chosen from one of odd numbered sequences is set forth in SEQ ID NO: 1 through SEQ ID NO: 6649, a degenerate variant thereof, or a fragment thereof, under conditions permitting hybridization and detecting the presence of hybridization complexes in the sample, wherein hybridization complexes indicate the presence of Alloiococcus otitidis in the sample.

Still other embodiments provide a method for the detection and/or identification of Alloiococcus otitidis in a biological sample comprising nucleotide sequence chosen from one of odd numbered sequences set forth in SEQ ID NO: 1 through SEQ ID NO: 6649, a degenerate variant thereof, or a fragment thereof, in the presence of nucleotides and a polymerase enzyme under conditions permitting primer extension and detecting the presence of primer extension products in the sample, wherein extension products indicate the presence of Alloiococcus otitidis in the sample.

Further embodiments provide a method for the detection and/or identification of Alloiococcus otitidis in a biological sample comprising contacting the sample with an antibody specific for a polypeptide comprising an amino acid sequence chosen from one of even numbered sequences set forth in SEQ ID NO: 2 through SEQ ID NO: 6650, a biological equivalent thereof, or a fragment thereof, under conditions permitting immune complex formation and detecting the presence of immune complexes in the sample, wherein immune complexes indicate the presence of Alloiococcus otitidis in the sample.

In certain embodiments, provided is a method for the detection and/or identification of antibodies to Alloiococcus otitidis in a biological sample comprising contacting the sample with a polypeptide comprising an amino acid sequence chosen from one of even numbered sequences set forth in SEQ ID NO: 2 through SEQ ID NO: 6650, a biological equivalent thereof, or a fragment thereof, under conditions permitting immune complex formation and detecting the presence of immune complexes in the sample, wherein immune complexes indicate the presence of Alloiococcus otitidis in the sample.

Other embodiments of the invention provide a kit comprising a container containing an isolated polynucleotide comprising an nucleotide sequence chosen from one of odd numbered sequences set forth in SEQ ID NO: 1 through SEQ ID NO: 6649, a degenerate variant thereof, or a fragment thereof. In a preferred embodiment, the polynucleotide is a primer or a probe, wherein when the polynucleotide is a primer, the kit further comprises a container containing a polymerase. In another embodiment, the kit further comprises a container containing dNTP.

Provided further is a kit comprising a container containing an antibody that immunospecifically binds to a polypeptide comprising the amino acid sequence chosen from one of even numbered sequences set forth in SEQ ID NO: 2 through SEQ ID NO: 6650, a biological equivalent thereof, or a fragment thereof.

Provided also is a kit comprising a container containing an antibody that immunospecifically binds to a fusion polypeptide comprising at least the amino acid sequence chosen from one of even numbered sequences set forth in SEQ ID NO: 2 through SEQ ID NO: 6650, a biological equivalent thereof, or a fragment thereof.

In a preferred embodiment of the invention, there is provided a genetically engineered host cell, transfected, transformed or infected with a recombinant expression vector comprising a nucleotide sequence having at least about 70% identity to a nucleotide sequence chosen from one of odd numbered sequences set forth in SEQ ID NO: 1 through SEQ ID NO: 6649, a complement thereof, a degenerate variant thereof, or a fragment thereof under conditions suitable to produce one of the polypeptides of even numbered sequences set out in SEQ ID NO: 2 through SEQ ID NO: 6650; and recovering the polypeptide.

Other features and advantages of the invention will be apparent from the following detailed description, from the preferred embodiments thereof, and from the claims.

DETAILED DESCRIPTION OF THE INVENTION

The invention described herein addresses the need for an Alloiococcus otitidis immunogenic composition that is effective in preventing most or all of the disease caused by Alloiococcus otitidis. The invention further addresses the need for methods of diagnosing Alloiococcus otitidis infection. The Applicants have identified novel Alloiococcus otitidis open reading frames (ORFs), which encode antigenic polypeptides. More particularly, the newly identified ORFs encode polypeptides that are surface localized (i.e., exposed) on Alloiococcus otitidis, and thus serve as potential antigenic polypeptides in immunogenic compositions. Thus, in certain embodiments, the invention comprises Alloiococcus otitidis polynucleotide ORFs encoding surface localized polypeptide antigens. In other embodiments, the present invention comprises surface localized antigenic polypeptides, encoded by the Alloiococcus otitidis ORFs.

In other embodiments, the invention comprises vectors comprising ORF sequences and host cells or animals transformed with these vectors. The invention also comprises transcriptional gene products of Alloiococcus otitidis ORFs, including, but not limited to mRNA, antisense RNA, antisense oligonucleotides, and ribozyme molecules, which are used to inhibit or control growth of the microorganism. The invention relates also to methods of detecting Alloiococcus otitidis nucleic acids or polypeptides and kits for diagnosing Alloiococcus otitidis infection. The invention also relates to pharmaceutical compositions, in particular immunogenic compositions, for the prevention and/or treatment of bacterial infection, in particular infection caused by or exacerbated by Alloiococcus otitidis. In particular embodiments, the immunogenic compositions are used for the treatment or prevention of non-systemic diseases, particularly of the otitis media, which are induced or exacerbated by Alloiococcus otitidis.

A. IDENTIFYING ORFs WITHIN THE GENOMIC SEQUENCE OF ALLOIOCOCCUS OTITIDIS

The invention is directed in particular embodiments to the identification of polynucleotides, more particularly ORFs, which encode Alloiococcus otitidis polypeptides. The availability of the bacterial genomic sequences has begun to play an important role in the identification of vaccine candidates through genomics, transcriptional profiling, and proteomics, coupled with the information processing capabilities of bioinformatics (McAtee et al., 1998a; McAtee et al., 1998b; Pizza et al., 2000; Sonnenberg and Belisle, 1997; Weldingh et al., 1998; McAtee et al., 1998c). Thus, the Applicants have analyzed the Alloiococcus otitidis genomic sequences and utilized bioinformatics tools to identify the ORFs encoding polypeptides of the present invention. As described below, the ORFs were analyzed for a variety of characteristics.

Specifically, an extensive genomic analysis was performed in silico of the Alloiococcus otitidis genome using algorithms designed to identify genes that encode novel surface localized polypeptides or polypeptides with putative similarity to surface localized polypeptides in other organisms. Thus, a combined analysis of the Alloiococcus otitidis genome, using a unique set of three ORF finder algorithms (i.e., GLIMMER™, Salzberg et al., 1998, GeneMark™ (Lukashin and Borodovsky, 1998) and the Applicants' assignee's own programs), identified 3325 ORFs. The most stringent of the ORF finders; Glimmer™, identified 1529 ORFs; GeneMark™ identified 1,534 ORFs, while Applicants' assignee's ORF finders identified the most with 2706 ORFs.

For the purposes of this application, all ORFs with common stop codons are given the same ORF designation and will be treated as if they are the same ORF. In a number of instances, there are multiple start codons within a given ORF. These proteins of different length are indicated by a lower case letter suffix after the ORF number. For example, as shown in Table 2 below, ORF number 4a has a protein start beginning at nucleotide 3733, ORF number 4b has a protein start beginning at nucleotide 3049, and 4c has a protein start beginning or ending at nucleotide 2854 (these three sequences share a common ORF stop codon beginning at nucleotide 4152). As used herein, an ORF is defined as having one of three potential start site codons, ATG, GTG, TTG and one of three potential stop codons, TM, TAG, TGA. The lower limit of amino acid length used (e.g., ˜74 amino acids) may also cause the algorithms to overlook some reading frames. However, “true” reading frames become an increasingly rare as the ORFs become shorter.

The initial annotation of the Alloiococcus otitidis ORFs was performed using the Basic Local Alignment Search Tool (BLAST; version 2.0) Gapped search algorithm, BlastP, to identify homologous sequences (Altschul et al, 1997). A cutoff “E” value of anything <e⁻¹⁰ was considered significant. The non-redundant protein sequence databases used for the homology searches consisted of GenBank, SWISS-PROT, PIR, and TREMBL; these database sequences are updated daily. In the present invention, ORFs with a BlastP ‘E’ value result of >e⁻¹⁰ are considered to be unique to Alloiococcus otitidis. Alternate quantitative expression values other than BlastP “E”, e.g., percent identity, may also be used to compare database sequences with the Alloiococcus otitidis ORFs of the present invention.

A keyword search of the entire BLAST results was carried out using known or suspected target genes for immunogenic compositions, as well as using words that identified the location of a protein or function.

Several parameters were used to determine the partitioning of the predicted Alloiococcus otitidis polypeptides of the invention. For example, polypeptides destined for translocation across the cytoplasmic membrane encode a leader signal (also called signal sequence) composed of a central hydrophobic region flanked at the N-terminus by positively charged residues (Pugsley, 1993). A software program, called SignalP, which identifies signal peptides and their cleavage sites based on neural networks (Nielsen et al., 1997), was used in the present invention to analyze the amino acid sequence of an ORF for such signal peptides. The first 60 N-terminal amino acids of each ORF were analyzed by SignalP software using the Gram-positive software database. The output generated four separate values: maximum C, maximum Y, maximum S, and mean S. The S-score, or signal region, is the probability of the position belonging to the signal peptide. The C-score, or cleavage site, is the probability of the position being the first in the mature protein. The Y-score is the geometric average of the C-score and a smoothed derivative of the S-score. A conclusion of either a Yes or No is given next to each score. If all four conclusions are Yes, then a ‘YES’ is listed for that ORF (see Table 3 below); if three of the conclusions are Yes, then a ‘yes’ is listed for that ORF (see Table 4 below); if two of the conclusions are Yes, then a ‘maybe’ is listed for that ORF; for all other cases, a ‘No’ is listed for that ORF (see Table 5 below).

A software program, called HMM SignalP, which identifies signal peptides and their cleavage sites based on hidden Markov models (Nielsen et al., 1997), was used in the present invention to analyze the amino acid sequence of an ORF for such signal peptides. The first 60 N-terminal amino acids of each ORF were analyzed by HMM SignalP software using the Gram-positive software database. The output generates a value from 0.00 to 1.00, whereby any value greater than 0.5 is listed as being a ‘Signal Peptide’ (see Table 5 below) and any value less than 0.5 is listed as being a ‘Non-Secretory Protein’ (see Table 6 below).

To predict polypeptide localization in bacteria, the software program PSORT was used (Nakai, 1991). PSORT predicts localization of polypeptides to the ‘cytoplasm’, the ‘periplasm’, and/or the ‘cytoplasmic membrane’ for Gram-positive bacteria, as well as the ‘outer membrane’ for Gram-negative bacteria. Transmembrane (TM) domains of polypeptides were analyzed using the software program TopPred2 (Cserzo et al., 1997) (see Table 6 below).

The Hidden Markov Model (HMM) Pfam database (Sonnhammer, 1998) was used to identify Alloiococcus otitidis proteins that may belong to an existing protein family (see Table 7 below). Keyword searching of this output was further used to help identify additional vaccine candidates that may have been missed by the BLAST search criteria (see Table 8 below).

The Applicants also used proteomic methods that had previously been used for studying surface exposed proteins in Streptococcus pneumoniae to identify 242 ORFs of Alloiococcus otitidis that share some homology with ORFs encoding surface exposed proteins on Streptococcus pneumoniae (see Table 9).

The Applicants also developed a HMM using approximately 70 known prokaryotic proteins containing the LPXTG cell wall sorting signal, in order to predict cell wall proteins that are anchored to the peptidoglycan layer (Mazmanian et al., 1999; Navarre and Schneewind, 1999). The model used not only the LPXTG sequence, but also included two features of the downstream sequence; first the hydrophobic transmembrane domain and second, the positively charged carboxy-terminus (see Table 10).

A computer algorithm, called HMM Lipo, was developed by Applicant's assignee to predict lipoproteins using 131 biologically proven bacterial lipoproteins. The protein sequence from the start of the protein to the cysteine amino acid, plus the next two additional amino acids, were used to generate the HMM (Eddy, 1996) (see Table 11).

There are also a number of proteins that interact, non-covalently, with the peptidoglycan layer and are distinct from the LPXTG protein class described above. These proteins seem to have a consensus sequence at their carboxy terminus (Koebnik, 1995). The Applicants therefore developed and used a HMM of this region to identify any Alloiococcus otitidis genome-encoded proteins that may fall into this class of proteins (see Table 12).

Proteins that contain Arg-Gly-Asp (RGD) attachment motif, together with integrins that serve as their receptor, constitute a major recognition system for cell adhesion, and thus are putative Alloiococus otitidis cell surface antigens. RGD recognition is one mechanism used by microbes to gain entry into eukaryotic tissues (Stockbauer et al., 1999, Isberg and Nhieu, 1994). However, not all RGD-containing proteins mediate cell attachment. It has been demonstrated that RGD-containing peptides with a proline at the carboxy end (RDGP) are inactive in cell attachment assays (Pierschbacher and Rouslahti, 1987) and will be excluded from consideration. About 125 surface localized ORFs were identified that were found to contain the peptide sequence RDGX where X is not proline (see Table 13).

ORFs whose BlastP results predict for proteins that may be involved in capsule biosynthesis and transport were also identified based on BlastP analysis. In addition, three potential capsule loci within the Alloiococcus otitidis genome were also identified based BlastP analysis (see Tables 14 and 15).

BlastP analysis was also used to identify ORFs associated with sporulation in Alloiococcus otitidis (see Tables 16).

BlastP analysis of the Alloiococcus otitidis genomic sequence also resulted in the identification of 913 unique ORFs, or 653 unique Stop-Stop ORFs, that were shown to have a BlastP ‘E Value’ of >e⁻¹⁰ (see Table 17).

Three different ORF finder programs were also used to identify ORFs encoding polypeptides that could potentially be used in immunogenic compositions. Using the Glimmer™ ORF finder program 1530 ORFs were identified (see Table 18). Using the GeneMark™ ORF finder program 1536 ORFs were identified (see Table 19). The Applicants also identified 2343 ORFs using the ORF finder program of Applicant's assignee, which searches for one of the three potential Start codons between a Stop-Stop regions. It first looks for a ‘ATG’ Start codon but will accept either a ‘GTG’ or ‘TTG’ Start codon if found first (see Table 20). The Applicants' assignee's ORF finder program also detected 615 ORFs containing putative transmembrane regions The program searches for putative transmembrane regions between two Stop codons and a Start codon immediately upstream of this region (see Table 21).

The entire genomic sequence of the isolated Alloiococcus otitidis is set out in Seq. ID No. 6651. Alloiococcus otitidis ORFs encoding proteins/polypeptides that are contained within this genomic sequence can also be used in immunogenic compositions.

A complete listing of all the ORFs of Alloiococcus otitidis based on the above characteristics, and which are used in immunogenic compositions, is set out in Table 2.

In addition, Tables 3-21 represent 19 groups into which the ORFs identified according to the above characteristics of present invention have been classified. Thus, all of the groups described below are ORFs comprised within the Alloiococcus otitidis genome and identified as encoding putative surface localized polypeptides. These groups are not meant to limit the scope of the present invention, as analysis of additional ORF characteristics is contemplated. These additional characteristics, e.g., RGD sequence, may serve to further expand the total number of ORF groupings or to parse the presently identified ORFs into more defined groups, broader groups, narrower groups or group subsets. In addition, some ORFs will meet the criteria of more than one category, and will therefore appear in more than one of the following groups. TABLE 2 ALL CLAIMED ORFs ORF DNA SEQ ID Protein SEQ ID Number Number ORF Start Protein Start ORF Stop Number 1 Seq. ID No. 1 1149 1146 280 Seq. ID No. 2 2a Seq. ID No. 3 2227 2143 1271 Seq. ID No. 4 2b Seq. ID No. 5 2227 2203 1271 Seq. ID No. 6 4a Seq. ID No. 7 2827 3733 4152 Seq. ID No. 8 4b Seq. ID No. 9 2827 3049 4152 Seq. ID No. 10 4c Seq. ID No. 11 2827 2854 4152 Seq. ID No. 12 5 Seq. ID No. 13 5020 5011 4295 Seq. ID No. 14 7 Seq. ID No. 15 5792 5780 5001 Seq. ID No. 16 10 Seq. ID No. 17 7828 7807 5783 Seq. ID No. 18 11 Seq. ID No. 19 6198 6216 6449 Seq. ID No. 20 13a Seq. ID No. 21 6900 6879 6589 Seq. ID No. 22 16 Seq. ID No. 23 7100 7139 7390 Seq. ID No. 24 17 Seq. ID No. 25 8265 8247 7804 Seq. ID No. 26 18 Seq. ID No. 27 9571 9517 8210 Seq. ID No. 28 20 Seq. ID No. 29 10605 10605 9514 Seq. ID No. 30 21b Seq. ID No. 31 9485 9497 9793 Seq. ID No. 32 23a Seq. ID No. 33 11845 11374 10595 Seq. ID No. 34 23b Seq. ID No. 35 11845 11830 10595 Seq. ID No. 36 24 Seq. ID No. 37 12908 12905 11823 Seq. ID No. 38 32 Seq. ID No. 39 15875 15875 15789 Seq. ID No. 40 36 Seq. ID No. 41 19431 19386 18634 Seq. ID No. 42 37 Seq. ID No. 43 19372 19429 20076 Seq. ID No. 44 38a Seq. ID No. 45 21796 21769 20186 Seq. ID No. 46 38b Seq. ID No. 47 21796 21772 20186 Seq. ID No. 48 39a Seq. ID No. 49 22265 22238 21786 Seq. ID No. 50 39b Seq. ID No. 51 22265 22262 21786 Seq. ID No. 52 40 Seq. ID No. 53 23449 23437 22238 Seq. ID No. 54 41a Seq. ID No. 55 24645 24183 23434 Seq. ID No. 56 41b Seq. ID No. 57 24645 24402 23434 Seq. ID No. 58 41c Seq. ID No. 59 24645 24630 23434 Seq. ID No. 60 43b Seq. ID No. 61 25392 25353 24997 Seq. ID No. 62 43c Seq. ID No. 63 25392 25359 24997 Seq. ID No. 64 44a Seq. ID No. 65 25001 25028 25330 Seq. ID No. 66 44b Seq. ID No. 67 25001 25016 25330 Seq. ID No. 68 45 Seq. ID No. 69 25702 25654 25403 Seq. ID No. 70 46a Seq. ID No. 71 26225 26141 25800 Seq. ID No. 72 46b Seq. ID No. 73 26225 26153 25800 Seq. ID No. 74 47 Seq. ID No. 75 27661 27643 26195 Seq. ID No. 76 48a Seq. ID No. 77 29105 28781 27696 Seq. ID No. 78 48b Seq. ID No. 79 29105 28973 27696 Seq. ID No. 80 48c Seq. ID No. 81 29105 29090 27696 Seq. ID No. 82 50 Seq. ID No. 83 30169 30154 29102 Seq. ID No. 84 51a Seq. ID No. 85 31759 31072 30353 Seq. ID No. 86 51b Seq. ID No. 87 31759 31693 30353 Seq. ID No. 88 51c Seq. ID No. 89 31759 31741 30353 Seq. ID No. 90 55 Seq. ID No. 91 32149 32128 31895 Seq. ID No. 92 56b Seq. ID No. 93 32234 32231 31968 Seq. ID No. 94 57a Seq. ID No. 95 33738 33723 32455 Seq. ID No. 96 57b Seq. ID No. 97 33738 33732 32455 Seq. ID No. 98 58 Seq. ID No. 99 32611 32644 32934 Seq. ID No. 100 60a Seq. ID No. 101 34825 34786 33947 Seq. ID No. 102 60b Seq. ID No. 103 34825 34804 33947 Seq. ID No. 104 61 Seq. ID No. 105 34344 34344 34751 Seq. ID No. 106 62a Seq. ID No. 107 36496 36334 34877 Seq. ID No. 108 62b Seq. ID No. 109 36496 36415 34877 Seq. ID No. 110 62c Seq. ID No. 111 36496 36484 34877 Seq. ID No. 112 63a Seq. ID No. 113 35069 35102 35563 Seq. ID No. 114 63b Seq. ID No. 115 35069 35072 35563 Seq. ID No. 116 65a Seq. ID No. 117 37245 37158 36634 Seq. ID No. 118 65b Seq. ID No. 119 37245 37203 36634 Seq. ID No. 120 65c Seq. ID No. 121 37245 37242 36634 Seq. ID No. 122 66a Seq. ID No. 123 36563 36749 37030 Seq. ID No. 124 67 Seq. ID No. 125 37706 37694 37254 Seq. ID No. 126 69 Seq. ID No. 127 38141 38078 37803 Seq. ID No. 128 71 Seq. ID No. 129 37829 37862 38722 Seq. ID No. 130 73a Seq. ID No. 131 39233 39248 39472 Seq. ID No. 132 73b Seq. ID No. 133 39233 39245 39472 Seq. ID No. 134 74 Seq. ID No. 135 38701 38719 40068 Seq. ID No. 136 77 Seq. ID No. 137 40223 40232 41029 Seq. ID No. 138 79 Seq. ID No. 139 41098 41098 41607 Seq. ID No. 140 80a Seq. ID No. 141 41294 41375 41902 Seq. ID No. 142 80b Seq. ID No. 143 41294 41354 41902 Seq. ID No. 144 80c Seq. ID No. 145 41294 41300 41902 Seq. ID No. 146 81a Seq. ID No. 147 42667 42658 42107 Seq. ID No. 148 81b Seq. ID No. 149 42667 42664 42107 Seq. ID No. 150 83 Seq. ID No. 151 42875 42875 43096 Seq. ID No. 152 85a Seq. ID No. 153 43769 43976 44563 Seq. ID No. 154 85b Seq. ID No. 155 43769 43829 44563 Seq. ID No. 156 85c Seq. ID No. 157 43769 43811 44563 Seq. ID No. 158 86 Seq. ID No. 159 44846 44825 44592 Seq. ID No. 160 87a Seq. ID No. 161 45417 45315 45064 Seq. ID No. 162 87b Seq. ID No. 163 45417 45351 45064 Seq. ID No. 164 87c Seq. ID No. 165 45417 45402 45064 Seq. ID No. 166 88 Seq. ID No. 167 44548 44560 45258 Seq. ID No. 168 89 Seq. ID No. 169 45592 45550 45296 Seq. ID No. 170 91a Seq. ID No. 171 45068 45278 46252 Seq. ID No. 172 91b Seq. ID No. 173 45068 45194 46252 Seq. ID No. 174 91c Seq. ID No. 175 45068 45107 46252 Seq. ID No. 176 91d Seq. ID No. 177 45068 45074 46252 Seq. ID No. 178 93a Seq. ID No. 179 46421 46619 47563 Seq. ID No. 180 93b Seq. ID No. 181 46421 46454 47563 Seq. ID No. 182 93c Seq. ID No. 183 46421 46436 47563 Seq. ID No. 184 94 Seq. ID No. 185 47630 47630 47830 Seq. ID No. 186 95b Seq. ID No. 187 48482 48413 47895 Seq. ID No. 188 97b Seq. ID No. 189 48738 48723 48421 Seq. ID No. 190 99 Seq. ID No. 191 50295 50280 48739 Seq. ID No. 192 101 Seq. ID No. 193 49736 49766 50266 Seq. ID No. 194 102 Seq. ID No. 195 51996 51981 50311 Seq. ID No. 196 104a Seq. ID No. 197 52783 52738 52130 Seq. ID No. 198 104b Seq. ID No. 199 52783 52753 52130 Seq. ID No. 200 104c Seq. ID No. 201 52783 52780 52130 Seq. ID No. 202 105a Seq. ID No. 203 53486 53087 52710 Seq. ID No. 204 105b Seq. ID No. 205 53486 53375 52710 Seq. ID No. 206 106 Seq. ID No. 207 53716 53695 53102 Seq. ID No. 208 109a Seq. ID No. 209 54828 54606 53938 Seq. ID No. 210 109b Seq. ID No. 211 54828 54780 53938 Seq. ID No. 212 109c Seq. ID No. 213 54828 54807 53938 Seq. ID No. 214 109d Seq. ID No. 215 54828 54825 53938 Seq. ID No. 216 111a Seq. ID No. 217 55748 55580 54822 Seq. ID No. 218 111b Seq. ID No. 219 55748 55748 54822 Seq. ID No. 220 112a Seq. ID No. 221 56518 56494 55745 Seq. ID No. 222 112b Seq. ID No. 223 56518 56503 55745 Seq. ID No. 224 114 Seq. ID No. 225 57489 57459 56506 Seq. ID No. 226 115 Seq. ID No. 227 57509 57536 58264 Seq. ID No. 228 119a Seq. ID No. 229 58330 58573 59388 Seq. ID No. 230 119b Seq. ID No. 231 58330 58354 59388 Seq. ID No. 232 121 Seq. ID No. 233 59528 59540 60505 Seq. ID No. 234 124a Seq. ID No. 235 60496 61084 62028 Seq. ID No. 236 124b Seq. ID No. 237 60496 60913 62028 Seq. ID No. 238 124c Seq. ID No. 239 60496 60502 62028 Seq. ID No. 240 125 Seq. ID No. 241 62724 62700 62170 Seq. ID No. 242 127a Seq. ID No. 243 63580 63556 62900 Seq. ID No. 244 127b Seq. ID No. 245 63580 63559 62900 Seq. ID No. 246 127c Seq. ID No. 247 63580 63565 62900 Seq. ID No. 248 129a Seq. ID No. 249 65731 64381 63731 Seq. ID No. 250 129b Seq. ID No. 251 65731 64777 63731 Seq. ID No. 252 129c Seq. ID No. 253 65731 65728 63731 Seq. ID No. 254 132a Seq. ID No. 255 64857 64902 65162 Seq. ID No. 256 132b Seq. ID No. 257 64857 64875 65162 Seq. ID No. 258 132c Seq. ID No. 259 64857 64860 65162 Seq. ID No. 260 134 Seq. ID No. 261 66670 66667 65753 Seq. ID No. 262 135a Seq. ID No. 263 67444 67423 66671 Seq. ID No. 264 135b Seq. ID No. 265 67444 67444 66671 Seq. ID No. 266 137a Seq. ID No. 267 68103 68073 67597 Seq. ID No. 268 137b Seq. ID No. 269 68103 68100 67597 Seq. ID No. 270 138a Seq. ID No. 271 70062 69996 68104 Seq. ID No. 272 138b Seq. ID No. 273 70062 70032 68104 Seq. ID No. 274 142 Seq. ID No. 275 70135 70213 70539 Seq. ID No. 276 143 Seq. ID No. 277 71697 71697 70765 Seq. ID No. 278 144a Seq. ID No. 279 72593 72506 71721 Seq. ID No. 280 144b Seq. ID No. 281 72593 72545 71721 Seq. ID No. 282 144c Seq. ID No. 283 72593 72563 71721 Seq. ID No. 284 145a Seq. ID No. 285 74289 72996 72706 Seq. ID No. 286 145b Seq. ID No. 287 74289 73896 72706 Seq. ID No. 288 145c Seq. ID No. 289 74289 74157 72706 Seq. ID No. 290 145d Seq. ID No. 291 74289 74226 72706 Seq. ID No. 292 147 Seq. ID No. 293 74501 74504 75694 Seq. ID No. 294 151a Seq. ID No. 295 77145 77184 78218 Seq. ID No. 296 151b Seq. ID No. 297 77145 77163 78218 Seq. ID No. 298 152a Seq. ID No. 299 78163 78220 78813 Seq. ID No. 300 152b Seq. ID No. 301 78163 78166 78813 Seq. ID No. 302 153a Seq. ID No. 303 78814 79048 80013 Seq. ID No. 304 153b Seq. ID No. 305 78814 78973 80013 Seq. ID No. 306 153c Seq. ID No. 307 78814 78835 80013 Seq. ID No. 308 154 Seq. ID No. 309 80014 80020 80496 Seq. ID No. 310 155a Seq. ID No. 311 82026 81981 80719 Seq. ID No. 312 155b Seq. ID No. 313 82026 82014 80719 Seq. ID No. 314 157a Seq. ID No. 315 82976 82856 82566 Seq. ID No. 316 157b Seq. ID No. 317 82976 82958 82566 Seq. ID No. 318 158a Seq. ID No. 319 83433 83400 82972 Seq. ID No. 320 158b Seq. ID No. 321 83433 83415 82972 Seq. ID No. 322 160a Seq. ID No. 323 84411 84378 83584 Seq. ID No. 324 160b Seq. ID No. 325 84411 84408 83584 Seq. ID No. 326 162a Seq. ID No. 327 85333 84958 84479 Seq. ID No. 328 162b Seq. ID No. 329 85333 85117 84479 Seq. ID No. 330 162c Seq. ID No. 331 85333 85276 84479 Seq. ID No. 332 162d Seq. ID No. 333 85333 85285 84479 Seq. ID No. 334 162e Seq. ID No. 335 85333 85309 84479 Seq. ID No. 336 163 Seq. ID No. 337 84597 84609 85145 Seq. ID No. 338 164 Seq. ID No. 339 84797 84812 85264 Seq. ID No. 340 165a Seq. ID No. 341 86252 86144 85266 Seq. ID No. 342 165b Seq. ID No. 343 86252 86150 85266 Seq. ID No. 344 167 Seq. ID No. 345 86974 86959 86120 Seq. ID No. 346 169 Seq. ID No. 347 86178 86193 86720 Seq. ID No. 348 170 Seq. ID No. 349 86757 86790 87047 Seq. ID No. 350 171a Seq. ID No. 351 87777 87717 87316 Seq. ID No. 352 171b Seq. ID No. 353 87777 87762 87316 Seq. ID No. 354 172 Seq. ID No. 355 88726 88726 87785 Seq. ID No. 356 173 Seq. ID No. 357 87518 87560 87805 Seq. ID No. 358 174 Seq. ID No. 359 87942 87969 88196 Seq. ID No. 360 175 Seq. ID No. 361 89206 89194 88793 Seq. ID No. 362 176 Seq. ID No. 363 89592 89589 89224 Seq. ID No. 364 177a Seq. ID No. 365 90825 90801 90136 Seq. ID No. 366 177b Seq. ID No. 367 90825 90816 90136 Seq. ID No. 368 179a Seq. ID No. 369 90536 90599 90823 Seq. ID No. 370 179b Seq. ID No. 371 90536 90596 90823 Seq. ID No. 372 180a Seq. ID No. 373 92164 91072 90845 Seq. ID No. 374 180b Seq. ID No. 375 92164 92155 90845 Seq. ID No. 376 183a Seq. ID No. 377 91563 91608 91928 Seq. ID No. 378 184 Seq. ID No. 379 92612 92597 92160 Seq. ID No. 380 185 Seq. ID No. 381 92821 92821 92630 Seq. ID No. 382 186 Seq. ID No. 383 93331 93328 92825 Seq. ID No. 384 187a Seq. ID No. 385 92661 92706 93110 Seq. ID No. 386 187b Seq. ID No. 387 92661 92670 93110 Seq. ID No. 388 188 Seq. ID No. 389 93727 93718 93350 Seq. ID No. 390 189b Seq. ID No. 391 94349 94319 93780 Seq. ID No. 392 191b Seq. ID No. 393 93850 93877 94344 Seq. ID No. 394 192a Seq. ID No. 395 94748 94742 94350 Seq. ID No. 396 192b Seq. ID No. 397 94748 94748 94350 Seq. ID No. 398 193 Seq. ID No. 399 94912 94912 94739 Seq. ID No. 400 194a Seq. ID No. 401 94489 94528 94773 Seq. ID No. 402 194b Seq. ID No. 403 94489 94516 94773 Seq. ID No. 404 195 Seq. ID No. 405 95581 95527 94988 Seq. ID No. 406 196 Seq. ID No. 407 94854 94875 95147 Seq. ID No. 408 197a Seq. ID No. 409 95874 95862 95560 Seq. ID No. 410 197b Seq. ID No. 411 95874 95871 95560 Seq. ID No. 412 198a Seq. ID No. 413 96273 96237 95890 Seq. ID No. 414 198b Seq. ID No. 415 96273 96258 95890 Seq. ID No. 416 200 Seq. ID No. 417 96560 96557 96294 Seq. ID No. 418 201a Seq. ID No. 419 96178 96340 96564 Seq. ID No. 420 202 Seq. ID No. 421 96786 96786 96592 Seq. ID No. 422 203 Seq. ID No. 423 97210 97207 96776 Seq. ID No. 424 204 Seq. ID No. 425 97870 97867 97211 Seq. ID No. 426 205 Seq. ID No. 427 98245 98227 97871 Seq. ID No. 428 206 Seq. ID No. 429 98536 98524 98249 Seq. ID No. 430 207 Seq. ID No. 431 98031 98031 98282 Seq. ID No. 432 208a Seq. ID No. 433 99436 99367 98567 Seq. ID No. 434 208b Seq. ID No. 435 99436 99412 98567 Seq. ID No. 436 210 Seq. ID No. 437 99792 99738 99445 Seq. ID No. 438 211 Seq. ID No. 439 100364 100361 99738 Seq. ID No. 440 213 Seq. ID No. 441 101050 101020 100388 Seq. ID No. 442 215a Seq. ID No. 443 101510 101444 101058 Seq. ID No. 444 218 Seq. ID No. 445 102897 102885 102442 Seq. ID No. 446 219 Seq. ID No. 447 104259 104244 103060 Seq. ID No. 448 220a Seq. ID No. 449 106476 106326 104386 Seq. ID No. 450 220b Seq. ID No. 451 106476 106428 104386 Seq. ID No. 452 220c Seq. ID No. 453 106476 106476 104386 Seq. ID No. 454 223a Seq. ID No. 455 105032 105092 105457 Seq. ID No. 456 223b Seq. ID No. 457 105032 105065 105457 Seq. ID No. 458 226a Seq. ID No. 459 107077 106960 106580 Seq. ID No. 460 226b Seq. ID No. 461 107077 107050 106580 Seq. ID No. 462 227 Seq. ID No. 463 107524 107506 107096 Seq. ID No. 464 228a Seq. ID No. 465 111563 111203 107883 Seq. ID No. 466 228b Seq. ID No. 467 111563 111269 107883 Seq. ID No. 468 228c Seq. ID No. 469 111563 111461 107883 Seq. ID No. 470 228d Seq. ID No. 471 111563 111542 107883 Seq. ID No. 472 232a Seq. ID No. 473 108687 108723 109223 Seq. ID No. 474 232b Seq. ID No. 475 108687 108690 109223 Seq. ID No. 476 235a Seq. ID No. 477 110593 110707 111144 Seq. ID No. 478 235b Seq. ID No. 479 110593 110626 111144 Seq. ID No. 480 236a Seq. ID No. 481 115224 115071 111643 Seq. ID No. 482 236b Seq. ID No. 483 115224 115212 111643 Seq. ID No. 484 236c Seq. ID No. 485 115224 115221 111643 Seq. ID No. 486 239a Seq. ID No. 487 111971 112139 112507 Seq. ID No. 488 239b Seq. ID No. 489 111971 112097 112507 Seq. ID No. 490 239c Seq. ID No. 491 111971 112085 112507 Seq. ID No. 492 240 Seq. ID No. 493 112508 112601 112867 Seq. ID No. 494 241 Seq. ID No. 495 113123 113129 113374 Seq. ID No. 496 245a Seq. ID No. 497 116934 116292 115537 Seq. ID No. 498 245b Seq. ID No. 499 116934 116775 115537 Seq. ID No. 500 245c Seq. ID No. 501 116934 116895 115537 Seq. ID No. 502 246a Seq. ID No. 503 118257 118056 117070 Seq. ID No. 504 246b Seq. ID No. 505 118257 118245 117070 Seq. ID No. 506 247 Seq. ID No. 507 117578 117584 118102 Seq. ID No. 508 248a Seq. ID No. 509 119490 119358 118264 Seq. ID No. 510 248b Seq. ID No. 511 119490 119478 118264 Seq. ID No. 512 249a Seq. ID No. 513 121252 121225 119774 Seq. ID No. 514 249b Seq. ID No. 515 121252 121252 119774 Seq. ID No. 516 251 Seq. ID No. 517 122162 122150 121326 Seq. ID No. 518 253a Seq. ID No. 519 122435 122387 122163 Seq. ID No. 520 253b Seq. ID No. 521 122435 122432 122163 Seq. ID No. 522 254 Seq. ID No. 523 123069 123045 122416 Seq. ID No. 524 255a Seq. ID No. 525 124654 123817 123116 Seq. ID No. 526 255b Seq. ID No. 527 124654 124408 123116 Seq. ID No. 528 255c Seq. ID No. 529 124654 124639 123116 Seq. ID No. 530 255d Seq. ID No. 531 124654 124645 123116 Seq. ID No. 532 258 Seq. ID No. 533 125557 125539 124658 Seq. ID No. 534 259a Seq. ID No. 535 126322 126256 125558 Seq. ID No. 536 259b Seq. ID No. 537 126322 126292 125558 Seq. ID No. 538 259c Seq. ID No. 539 126322 126298 125558 Seq. ID No. 540 260 Seq. ID No. 541 126904 126901 126533 Seq. ID No. 542 262 Seq. ID No. 543 127474 127474 126965 Seq. ID No. 544 263a Seq. ID No. 545 126519 126645 126968 Seq. ID No. 546 263b Seq. ID No. 547 126519 126603 126968 Seq. ID No. 548 264b Seq. ID No. 549 126969 127005 127382 Seq. ID No. 550 265 Seq. ID No. 551 128443 128389 127691 Seq. ID No. 552 267b Seq. ID No. 553 129002 128912 128487 Seq. ID No. 554 267c Seq. ID No. 555 129002 128996 128487 Seq. ID No. 556 268 Seq. ID No. 557 128485 128500 128733 Seq. ID No. 558 269a Seq. ID No. 559 129717 129609 129055 Seq. ID No. 560 269b Seq. ID No. 561 129717 129708 129055 Seq. ID No. 562 271a Seq. ID No. 563 131163 131118 129856 Seq. ID No. 564 271b Seq. ID No. 565 131163 131151 129856 Seq. ID No. 566 273a Seq. ID No. 567 133346 132791 131694 Seq. ID No. 568 273b Seq. ID No. 569 133346 133343 131694 Seq. ID No. 570 277a Seq. ID No. 571 135131 134891 134046 Seq. ID No. 572 277b Seq. ID No. 573 135131 135077 134046 Seq. ID No. 574 277c Seq. ID No. 575 135131 135119 134046 Seq. ID No. 576 279a Seq. ID No. 577 135434 135626 135994 Seq. ID No. 578 279b Seq. ID No. 579 135434 135437 135994 Seq. ID No. 580 280a Seq. ID No. 581 138094 137200 136100 Seq. ID No. 582 280b Seq. ID No. 583 138094 137593 136100 Seq. ID No. 584 280c Seq. ID No. 585 138094 137926 136100 Seq. ID No. 586 280d Seq. ID No. 587 138094 138052 136100 Seq. ID No. 588 282 Seq. ID No. 589 139430 139388 139116 Seq. ID No. 590 283a Seq. ID No. 591 138704 138719 139567 Seq. ID No. 592 283b Seq. ID No. 593 138704 138710 139567 Seq. ID No. 594 284a Seq. ID No. 595 139568 139592 140257 Seq. ID No. 596 284b Seq. ID No. 597 139568 139574 140257 Seq. ID No. 598 285b Seq. ID No. 599 141025 141022 140702 Seq. ID No. 600 286a Seq. ID No. 601 140271 140286 141035 Seq. ID No. 602 286b Seq. ID No. 603 140271 140277 141035 Seq. ID No. 604 287 Seq. ID No. 605 142180 142153 141284 Seq. ID No. 606 290a Seq. ID No. 607 142653 142590 142177 Seq. ID No. 608 290b Seq. ID No. 609 142653 142638 142177 Seq. ID No. 610 293 Seq. ID No. 611 142822 142855 143292 Seq. ID No. 612 294 Seq. ID No. 613 143980 143974 143411 Seq. ID No. 614 296 Seq. ID No. 615 146154 146151 143974 Seq. ID No. 616 297 Seq. ID No. 617 144242 144227 143988 Seq. ID No. 618 300b Seq. ID No. 619 145417 145420 145899 Seq. ID No. 620 301a Seq. ID No. 621 147294 147237 146278 Seq. ID No. 622 301b Seq. ID No. 623 147294 147264 146278 Seq. ID No. 624 304a Seq. ID No. 625 149441 149135 147252 Seq. ID No. 626 304b Seq. ID No. 627 149441 149423 147252 Seq. ID No. 628 307 Seq. ID No. 629 149829 149781 149401 Seq. ID No. 630 308 Seq. ID No. 631 150040 150016 149783 Seq. ID No. 632 309 Seq. ID No. 633 149973 149973 150149 Seq. ID No. 634 310 Seq. ID No. 635 151326 151308 150298 Seq. ID No. 636 311 Seq. ID No. 637 153222 153168 151447 Seq. ID No. 638 313a Seq. ID No. 639 153970 153457 153188 Seq. ID No. 640 313b Seq. ID No. 641 153970 153496 153188 Seq. ID No. 642 313c Seq. ID No. 643 153970 153952 153188 Seq. ID No. 644 313d Seq. ID No. 645 153970 153955 153188 Seq. ID No. 646 313e Seq. ID No. 647 153970 153961 153188 Seq. ID No. 648 315 Seq. ID No. 649 154835 154826 153939 Seq. ID No. 650 316a Seq. ID No. 651 155263 155209 154826 Seq. ID No. 652 317a Seq. ID No. 653 155877 155646 155287 Seq. ID No. 654 317b Seq. ID No. 655 155877 155865 155287 Seq. ID No. 656 318a Seq. ID No. 657 157499 157280 156426 Seq. ID No. 658 318b Seq. ID No. 659 157499 157304 156426 Seq. ID No. 660 318c Seq. ID No. 661 157499 157367 156426 Seq. ID No. 662 318d Seq. ID No. 663 157499 157451 156426 Seq. ID No. 664 318e Seq. ID No. 665 157499 157460 156426 Seq. ID No. 666 320 Seq. ID No. 667 156670 156700 156975 Seq. ID No. 668 321 Seq. ID No. 669 158142 158139 157312 Seq. ID No. 670 323a Seq. ID No. 671 158413 158341 158129 Seq. ID No. 672 323b Seq. ID No. 673 158413 158395 158129 Seq. ID No. 674 324 Seq. ID No. 675 159203 159200 158373 Seq. ID No. 676 327a Seq. ID No. 677 159964 159682 159233 Seq. ID No. 678 327b Seq. ID No. 679 159964 159844 159233 Seq. ID No. 680 327c Seq. ID No. 681 159964 159937 159233 Seq. ID No. 682 329 Seq. ID No. 683 161034 161034 159934 Seq. ID No. 684 330a Seq. ID No. 685 161885 162272 163120 Seq. ID No. 686 330b Seq. ID No. 687 161885 161975 163120 Seq. ID No. 688 330c Seq. ID No. 689 161885 161888 163120 Seq. ID No. 690 331 Seq. ID No. 691 162945 162951 163187 Seq. ID No. 692 332 Seq. ID No. 693 163441 163441 163238 Seq. ID No. 694 333 Seq. ID No. 695 163242 163248 163478 Seq. ID No. 696 334 Seq. ID No. 697 163339 163339 163563 Seq. ID No. 698 335a Seq. ID No. 699 163139 163193 163786 Seq. ID No. 700 335b Seq. ID No. 701 163139 163178 163786 Seq. ID No. 702 337 Seq. ID No. 703 163774 163798 164847 Seq. ID No. 704 338a Seq. ID No. 705 164835 164961 165473 Seq. ID No. 706 338b Seq. ID No. 707 164835 164952 165473 Seq. ID No. 708 338c Seq. ID No. 709 164835 164889 165473 Seq. ID No. 710 341a Seq. ID No. 711 165550 165709 166422 Seq. ID No. 712 341b Seq. ID No. 713 165550 165550 166422 Seq. ID No. 714 342a Seq. 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ID No. 749 171289 171334 172113 Seq. ID No. 750 350b Seq. ID No. 751 171289 171304 172113 Seq. ID No. 752 351 Seq. ID No. 753 172083 172116 172757 Seq. ID No. 754 352a Seq. ID No. 755 172736 173237 173545 Seq. ID No. 756 352b Seq. ID No. 757 172736 173222 173545 Seq. ID No. 758 352c Seq. ID No. 759 172736 172754 173545 Seq. ID No. 760 354a Seq. ID No. 761 173511 173913 174341 Seq. ID No. 762 354b Seq. ID No. 763 173511 173565 174341 Seq. ID No. 764 354c Seq. ID No. 765 173511 173535 174341 Seq. ID No. 766 355 Seq. ID No. 767 174702 174594 174361 Seq. ID No. 768 356a Seq. ID No. 769 174424 174847 175176 Seq. ID No. 770 356b Seq. ID No. 771 174424 174610 175176 Seq. ID No. 772 356c Seq. ID No. 773 174424 174538 175176 Seq. ID No. 774 356d Seq. ID No. 775 174424 174469 175176 Seq. ID No. 776 358a Seq. ID No. 777 175629 176586 176951 Seq. ID No. 778 358b Seq. ID No. 779 175629 175692 176951 Seq. ID No. 780 358c Seq. ID No. 781 175629 175653 176951 Seq. ID No. 782 362 Seq. ID No. 783 177179 177206 178258 Seq. ID No. 784 365a Seq. ID No. 785 178795 178840 179430 Seq. ID No. 786 365b Seq. ID No. 787 178795 178807 179430 Seq. ID No. 788 366b Seq. ID No. 789 179373 179436 180101 Seq. ID No. 790 366c Seq. ID No. 791 179373 179427 180101 Seq. ID No. 792 367a Seq. ID No. 793 181005 180984 180184 Seq. ID No. 794 367b Seq. ID No. 795 181005 181002 180184 Seq. ID No. 796 371a Seq. ID No. 797 181201 181216 181662 Seq. ID No. 798 371b Seq. ID No. 799 181201 181204 181662 Seq. ID No. 800 372a Seq. ID No. 801 184610 183770 181809 Seq. ID No. 802 372b Seq. ID No. 803 184610 184463 181809 Seq. ID No. 804 372c Seq. ID No. 805 184610 184562 181809 Seq. ID No. 806 372d Seq. ID No. 807 184610 184598 181809 Seq. ID No. 808 374 Seq. ID No. 809 182287 182368 182628 Seq. ID No. 810 377a Seq. ID No. 811 183658 183769 184497 Seq. ID No. 812 377b Seq. ID No. 813 183658 183682 184497 Seq. ID No. 814 378a Seq. ID No. 815 185701 185635 184616 Seq. ID No. 816 378b Seq. 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ID No. 1911 494411 494498 495802 Seq. ID No. 1912 949d Seq. ID No. 1913 494411 494435 495802 Seq. ID No. 1914 950 Seq. ID No. 1915 496174 496171 495929 Seq. ID No. 1916 951a Seq. ID No. 1917 495906 495984 496895 Seq. ID No. 1918 951b Seq. ID No. 1919 495906 495915 496895 Seq. ID No. 1920 952a Seq. ID No. 1921 497115 497547 498344 Seq. ID No. 1922 952b Seq. ID No. 1923 497115 497211 498344 Seq. ID No. 1924 954 Seq. ID No. 1925 498503 498518 499984 Seq. ID No. 1926 955a Seq. ID No. 1927 500596 500569 500297 Seq. ID No. 1928 955b Seq. ID No. 1929 500596 500575 500297 Seq. ID No. 1930 956 Seq. ID No. 1931 500019 500019 501308 Seq. ID No. 1932 958a Seq. ID No. 1933 501309 501417 501866 Seq. ID No. 1934 958b Seq. ID No. 1935 501309 501309 501866 Seq. ID No. 1936 959 Seq. ID No. 1937 501978 501993 502364 Seq. ID No. 1938 961a Seq. ID No. 1939 502392 502446 502943 Seq. ID No. 1940 961b Seq. ID No. 1941 502392 502425 502943 Seq. ID No. 1942 961c Seq. ID No. 1943 502392 502413 502943 Seq. ID No. 1944 963 Seq. ID No. 1945 502951 502978 503949 Seq. ID No. 1946 965a Seq. ID No. 1947 503950 503974 504930 Seq. ID No. 1948 965b Seq. ID No. 1949 503950 503965 504930 Seq. ID No. 1950 966a Seq. ID No. 1951 504879 504990 506417 Seq. ID No. 1952 966b Seq. ID No. 1953 504879 504975 506417 Seq. ID No. 1954 967a Seq. ID No. 1955 506365 506407 506805 Seq. ID No. 1956 967b Seq. ID No. 1957 506365 506377 506805 Seq. ID No. 1958 968 Seq. ID No. 1959 507166 507184 507951 Seq. ID No. 1960 969 Seq. ID No. 1961 510913 510913 508775 Seq. ID No. 1962 972a Seq. ID No. 1963 512618 512444 511044 Seq. ID No. 1964 972b Seq. ID No. 1965 512618 512603 511044 Seq. ID No. 1966 976 Seq. ID No. 1967 512815 512863 514659 Seq. ID No. 1968 977a Seq. ID No. 1969 515753 515654 514809 Seq. ID No. 1970 977b Seq. ID No. 1971 515753 515738 514809 Seq. ID No. 1972 978a Seq. ID No. 1973 516892 516718 516326 Seq. ID No. 1974 978b Seq. ID No. 1975 516892 516856 516326 Seq. ID No. 1976 979 Seq. ID No. 1977 517178 517178 517002 Seq. ID No. 1978 980 Seq. ID No. 1979 518090 518063 517239 Seq. ID No. 1980 981a Seq. ID No. 1981 517537 517717 517962 Seq. ID No. 1982 982 Seq. ID No. 1983 519084 519033 518146 Seq. ID No. 1984 984a Seq. ID No. 1985 519141 519309 519995 Seq. ID No. 1986 984b Seq. ID No. 1987 519141 519216 519995 Seq. ID No. 1988 986 Seq. ID No. 1989 520057 520066 521073 Seq. ID No. 1990 987 Seq. ID No. 1991 521626 521614 521147 Seq. ID No. 1992 988a Seq. ID No. 1993 522445 522070 521627 Seq. ID No. 1994 988b Seq. ID No. 1995 522445 522328 521627 Seq. ID No. 1996 988c Seq. ID No. 1997 522445 522391 521627 Seq. ID No. 1998 988d Seq. ID No. 1999 522445 522433 521627 Seq. ID No. 2000 991 Seq. ID No. 2001 522779 522782 523339 Seq. ID No. 2002 992 Seq. ID No. 2003 524472 524454 523420 Seq. ID No. 2004 993 Seq. ID No. 2005 523372 523387 524031 Seq. ID No. 2006 994 Seq. ID No. 2007 523709 523763 524269 Seq. ID No. 2008 995 Seq. ID No. 2009 524843 524789 524508 Seq. 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ID No. 2299 604610 604631 605278 Seq. ID No. 2300 1149 Seq. ID No. 2301 607200 607170 605347 Seq. ID No. 2302 1152a Seq. ID No. 2303 607234 608383 608667 Seq. ID No. 2304 1152b Seq. ID No. 2305 607234 607984 608667 Seq. ID No. 2306 1152c Seq. ID No. 2307 607234 607690 608667 Seq. ID No. 2308 1152d Seq. ID No. 2309 607234 607429 608667 Seq. ID No. 2310 1152e Seq. ID No. 2311 607234 607297 608667 Seq. ID No. 2312 1152f Seq. ID No. 2313 607234 607261 608667 Seq. ID No. 2314 1152g Seq. ID No. 2315 607234 607252 608667 Seq. ID No. 2316 1155a Seq. ID No. 2317 608668 609631 610128 Seq. ID No. 2318 1155b Seq. ID No. 2319 608668 609508 610128 Seq. ID No. 2320 1155c Seq. ID No. 2321 608668 609319 610128 Seq. ID No. 2322 1155d Seq. ID No. 2323 608668 609193 610128 Seq. ID No. 2324 1155e Seq. ID No. 2325 608668 608896 610128 Seq. ID No. 2326 1155f Seq. ID No. 2327 608668 608683 610128 Seq. ID No. 2328 1155g Seq. ID No. 2329 608668 608671 610128 Seq. ID No. 2330 1158a Seq. 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ID No. 2651 696061 696046 695036 Seq. ID No. 2652 1289 Seq. ID No. 2653 695318 695384 695629 Seq. ID No. 2654 1290 Seq. ID No. 2655 696712 696700 696062 Seq. ID No. 2656 1293a Seq. ID No. 2657 696820 697045 698178 Seq. ID No. 2658 1293b Seq. ID No. 2659 696820 696829 698178 Seq. ID No. 2660 1294a Seq. ID No. 2661 698539 698527 698231 Seq. ID No. 2662 1295 Seq. ID No. 2663 698150 698171 698863 Seq. ID No. 2664 1297a Seq. ID No. 2665 699177 699198 699776 Seq. ID No. 2666 1297b Seq. ID No. 2667 699177 699180 699776 Seq. ID No. 2668 1300 Seq. ID No. 2669 699972 699981 702449 Seq. ID No. 2670 1302 Seq. ID No. 2671 702563 702629 703615 Seq. ID No. 2672 1305a Seq. ID No. 2673 703701 703719 704396 Seq. ID No. 2674 1305b Seq. ID No. 2675 703701 703710 704396 Seq. ID No. 2676 1305c Seq. ID No. 2677 703701 703701 704396 Seq. ID No. 2678 1308a Seq. ID No. 2679 704332 704872 705273 Seq. ID No. 2680 1308b Seq. ID No. 2681 704332 704452 705273 Seq. ID No. 2682 1308c Seq. ID No. 2683 704332 704362 705273 Seq. ID No. 2684 1308d Seq. ID No. 2685 704332 704344 705273 Seq. ID No. 2686 1308e Seq. ID No. 2687 704332 704332 705273 Seq. ID No. 2688 1311 Seq. ID No. 2689 705580 705598 706314 Seq. ID No. 2690 1314b Seq. ID No. 2691 707728 707725 707432 Seq. ID No. 2692 1315 Seq. ID No. 2693 706311 706311 708119 Seq. ID No. 2694 1316 Seq. ID No. 2695 708319 708325 708573 Seq. ID No. 2696 1317 Seq. ID No. 2697 709234 709210 708947 Seq. ID No. 2698 1318 Seq. ID No. 2699 708258 708261 709274 Seq. ID No. 2700 1319a Seq. ID No. 2701 709369 709570 710250 Seq. ID No. 2702 1319b Seq. ID No. 2703 709369 709390 710250 Seq. ID No. 2704 1320a Seq. ID No. 2705 710244 710745 711068 Seq. ID No. 2706 1320b Seq. ID No. 2707 710244 710400 711068 Seq. ID No. 2708 1320c Seq. ID No. 2709 710244 710250 711068 Seq. ID No. 2710 1321 Seq. ID No. 2711 711047 711068 711586 Seq. ID No. 2712 1322a Seq. ID No. 2713 711571 711586 711831 Seq. ID No. 2714 1322b Seq. ID No. 2715 711571 711583 711831 Seq. ID No. 2716 1323b Seq. ID No. 2717 712308 712248 711997 Seq. ID No. 2718 1324 Seq. ID No. 2719 711914 711917 712600 Seq. ID No. 2720 1326a Seq. ID No. 2721 712714 712729 713361 Seq. ID No. 2722 1326b Seq. ID No. 2723 712714 712723 713361 Seq. ID No. 2724 1326c Seq. ID No. 2725 712714 712720 713361 Seq. ID No. 2726 1333 Seq. ID No. 2727 713541 713541 716393 Seq. ID No. 2728 1334a Seq. ID No. 2729 716775 716739 716479 Seq. ID No. 2730 1334b Seq. ID No. 2731 716775 716748 716479 Seq. ID No. 2732 1335a Seq. ID No. 2733 717513 717270 716776 Seq. ID No. 2734 1335b Seq. ID No. 2735 717513 717462 716776 Seq. ID No. 2736 1337 Seq. ID No. 2737 716522 716558 718135 Seq. ID No. 2738 1338 Seq. ID No. 2739 718855 718855 718586 Seq. ID No. 2740 1340a Seq. ID No. 2741 718451 718490 718822 Seq. ID No. 2742 1340b Seq. ID No. 2743 718451 718466 718822 Seq. ID No. 2744 1341a Seq. ID No. 2745 718816 718858 719163 Seq. ID No. 2746 1341c Seq. ID No. 2747 718816 718822 719163 Seq. ID No. 2748 1344a Seq. ID No. 2749 719333 719396 720334 Seq. ID No. 2750 1344b Seq. ID No. 2751 719333 719381 720334 Seq. ID No. 2752 1348 Seq. ID No. 2753 720382 720400 721263 Seq. ID No. 2754 1349a Seq. ID No. 2755 721264 721312 722295 Seq. ID No. 2756 1349b Seq. ID No. 2757 721264 721276 722295 Seq. ID No. 2758 1349c Seq. ID No. 2759 721264 721267 722295 Seq. ID No. 2760 1350a Seq. ID No. 2761 722342 722369 722797 Seq. ID No. 2762 1350b Seq. ID No. 2763 722342 722348 722797 Seq. ID No. 2764 1353 Seq. ID No. 2765 722851 722869 723843 Seq. ID No. 2766 1355 Seq. ID No. 2767 723944 723944 725668 Seq. ID No. 2768 1358a Seq. ID No. 2769 725732 725753 726643 Seq. ID No. 2770 1358b Seq. ID No. 2771 725732 725732 726643 Seq. ID No. 2772 1359 Seq. ID No. 2773 726616 726640 727635 Seq. ID No. 2774 1361 Seq. ID No. 2775 727639 727651 728580 Seq. ID No. 2776 1364a Seq. ID No. 2777 730140 730065 729379 Seq. ID No. 2778 1364b Seq. ID No. 2779 730140 730092 729379 Seq. ID No. 2780 1364c Seq. ID No. 2781 730140 730107 729379 Seq. ID No. 2782 1365b Seq. ID No. 2783 729761 729827 730129 Seq. ID No. 2784 1366a Seq. ID No. 2785 730210 730483 730836 Seq. ID No. 2786 1366b Seq. ID No. 2787 730210 730243 730836 Seq. ID No. 2788 1367 Seq. ID No. 2789 730970 730988 732001 Seq. ID No. 2790 1368 Seq. ID No. 2791 732002 732038 733033 Seq. ID No. 2792 1371 Seq. ID No. 2793 733169 733175 734359 Seq. ID No. 2794 1373a Seq. ID No. 2795 734383 734389 735144 Seq. ID No. 2796 1373b Seq. ID No. 2797 734383 734386 735144 Seq. ID No. 2798 1374 Seq. ID No. 2799 735111 735144 736679 Seq. ID No. 2800 1375 Seq. ID No. 2801 737472 737457 737191 Seq. ID No. 2802 1377 Seq. ID No. 2803 736676 736730 738028 Seq. ID No. 2804 1378 Seq. ID No. 2805 738364 738346 738119 Seq. ID No. 2806 1379 Seq. ID No. 2807 738645 738612 738340 Seq. ID No. 2808 1380 Seq. ID No. 2809 738987 738954 738646 Seq. ID No. 2810 1381a Seq. ID No. 2811 738197 738560 739288 Seq. ID No. 2812 1381b Seq. ID No. 2813 738197 738221 739288 Seq. ID No. 2814 1382 Seq. ID No. 2815 739289 739298 739879 Seq. ID No. 2816 1383 Seq. ID No. 2817 739834 739906 740064 Seq. ID No. 2818 1384a Seq. ID No. 2819 740592 740637 740843 Seq. ID No. 2820 1384b Seq. ID No. 2821 740592 740613 740843 Seq. ID No. 2822 1384c Seq. ID No. 2823 740592 740607 740843 Seq. ID No. 2824 1386a Seq. ID No. 2825 740904 740955 741692 Seq. ID No. 2826 1386b Seq. ID No. 2827 740904 740949 741692 Seq. ID No. 2828 1387a Seq. ID No. 2829 742161 741981 741694 Seq. ID No. 2830 1388b Seq. ID No. 2831 741439 741448 741723 Seq. ID No. 2832 1389a Seq. ID No. 2833 742245 742329 742586 Seq. ID No. 2834 1393a Seq. ID No. 2835 744190 744004 743774 Seq. ID No. 2836 1393b Seq. ID No. 2837 744190 744088 743774 Seq. ID No. 2838 1393c Seq. ID No. 2839 744190 744118 743774 Seq. ID No. 2840 1393d Seq. ID No. 2841 744190 744172 743774 Seq. ID No. 2842 1394 Seq. ID No. 2843 741716 741716 744145 Seq. ID No. 2844 1395a Seq. ID No. 2845 743835 743886 744179 Seq. ID No. 2846 1396 Seq. ID No. 2847 744166 744166 744624 Seq. ID No. 2848 1397 Seq. ID No. 2849 745009 745003 744779 Seq. ID No. 2850 1398 Seq. ID No. 2851 745395 745395 745583 Seq. ID No. 2852 1399a Seq. ID No. 2853 746205 746151 745810 Seq. ID No. 2854 1399b Seq. ID No. 2855 746205 746178 745810 Seq. ID No. 2856 1400 Seq. ID No. 2857 745613 745613 745813 Seq. ID No. 2858 1401 Seq. ID No. 2859 745943 745943 746104 Seq. ID No. 2860 1402c Seq. ID No. 2861 746612 746558 746190 Seq. ID No. 2862 1405 Seq. ID No. 2863 746924 746924 749635 Seq. ID No. 2864 1407b Seq. ID No. 2865 751061 751055 750588 Seq. ID No. 2866 1408 Seq. ID No. 2867 749626 749647 751767 Seq. ID No. 2868 1409 Seq. ID No. 2869 751768 751768 754359 Seq. ID No. 2870 1410 Seq. ID No. 2871 754341 754374 755108 Seq. ID No. 2872 1411a Seq. ID No. 2873 755080 755485 755841 Seq. ID No. 2874 1411b Seq. 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ID No. 3067 800458 800458 801843 Seq. ID No. 3068 1486 Seq. ID No. 3069 801844 801853 802452 Seq. ID No. 3070 1487 Seq. ID No. 3071 802771 802768 802532 Seq. ID No. 3072 1488a Seq. ID No. 3073 802224 802977 803219 Seq. ID No. 3074 1488b Seq. ID No. 3075 802224 802917 803219 Seq. ID No. 3076 1488c Seq. ID No. 3077 802224 802788 803219 Seq. ID No. 3078 1488d Seq. ID No. 3079 802224 802464 803219 Seq. ID No. 3080 1488e Seq. ID No. 3081 802224 802431 803219 Seq. ID No. 3082 1488f Seq. ID No. 3083 802224 802377 803219 Seq. ID No. 3084 1488g Seq. ID No. 3085 802224 802323 803219 Seq. ID No. 3086 1489 Seq. ID No. 3087 803568 803550 803326 Seq. ID No. 3088 1490 Seq. ID No. 3089 803135 803330 803674 Seq. ID No. 3090 1494 Seq. ID No. 3091 803890 803929 805041 Seq. ID No. 3092 1497 Seq. ID No. 3093 805042 805048 806508 Seq. ID No. 3094 1498a Seq. ID No. 3095 806363 806543 807457 Seq. ID No. 3096 1498b Seq. ID No. 3097 806363 806423 807457 Seq. ID No. 3098 1498c Seq. ID No. 3099 806363 806396 807457 Seq. ID No. 3100 1498d Seq. ID No. 3101 806363 806393 807457 Seq. ID No. 3102 1499 Seq. ID No. 3103 809397 809382 808153 Seq. ID No. 3104 1502a Seq. ID No. 3105 809502 809565 809828 Seq. ID No. 3106 1502b Seq. ID No. 3107 809502 809502 809828 Seq. ID No. 3108 1503a Seq. ID No. 3109 809829 809847 810431 Seq. ID No. 3110 1503b Seq. ID No. 3111 809829 809835 810431 Seq. ID No. 3112 1506a Seq. ID No. 3113 810510 810666 812906 Seq. ID No. 3114 1506b Seq. ID No. 3115 810510 810621 812906 Seq. ID No. 3116 1506c Seq. ID No. 3117 810510 810525 812906 Seq. ID No. 3118 1507a Seq. ID No. 3119 813291 813231 812944 Seq. ID No. 3120 1507b Seq. ID No. 3121 813291 813246 812944 Seq. ID No. 3122 1507c Seq. ID No. 3123 813291 813282 812944 Seq. ID No. 3124 1508 Seq. ID No. 3125 812996 813032 813340 Seq. ID No. 3126 1510a Seq. ID No. 3127 813521 813737 815023 Seq. ID No. 3128 1510b Seq. ID No. 3129 813521 813704 815023 Seq. ID No. 3130 1510c Seq. ID No. 3131 813521 813545 815023 Seq. ID No. 3132 1510d Seq. ID No. 3133 813521 813524 815023 Seq. ID No. 3134 1511 Seq. ID No. 3135 815078 815084 815920 Seq. ID No. 3136 1512 Seq. ID No. 3137 815892 815910 816524 Seq. ID No. 3138 1513a Seq. ID No. 3139 816525 816570 817034 Seq. ID No. 3140 1513b Seq. ID No. 3141 816525 816525 817034 Seq. ID No. 3142 1516 Seq. ID No. 3143 817055 817070 817537 Seq. ID No. 3144 1517a Seq. ID No. 3145 818704 818314 817709 Seq. ID No. 3146 1517b Seq. ID No. 3147 818704 818608 817709 Seq. ID No. 3148 1517c Seq. ID No. 3149 818704 818614 817709 Seq. ID No. 3150 1518a Seq. ID No. 3151 818067 818139 818636 Seq. ID No. 3152 1518b Seq. ID No. 3153 818067 818085 818636 Seq. ID No. 3154 1520 Seq. ID No. 3155 818738 818753 819112 Seq. ID No. 3156 1522 Seq. ID No. 3157 819117 819150 819596 Seq. ID No. 3158 1523 Seq. ID No. 3159 820780 820756 819647 Seq. ID No. 3160 1528 Seq. ID No. 3161 820968 820968 821969 Seq. ID No. 3162 1530a Seq. ID No. 3163 824730 824625 822091 Seq. ID No. 3164 1530b Seq. ID No. 3165 824730 824706 822091 Seq. ID No. 3166 1533a Seq. ID No. 3167 825870 825864 825565 Seq. ID No. 3168 1534a Seq. ID No. 3169 824975 825119 826375 Seq. ID No. 3170 1534b Seq. ID No. 3171 824975 824981 826375 Seq. ID No. 3172 1535a Seq. ID No. 3173 826056 826164 826391 Seq. ID No. 3174 1536a Seq. ID No. 3175 826336 826537 826698 Seq. ID No. 3176 1536b Seq. ID No. 3177 826336 826345 826698 Seq. ID No. 3178 1537 Seq. ID No. 3179 827893 827875 826907 Seq. ID No. 3180 1542 Seq. ID No. 3181 829139 829166 829660 Seq. ID No. 3182 1543 Seq. ID No. 3183 828142 828145 829974 Seq. ID No. 3184 1544 Seq. ID No. 3185 832325 832298 830493 Seq. ID No. 3186 1547a Seq. ID No. 3187 832494 832638 833225 Seq. ID No. 3188 1547b Seq. ID No. 3189 832494 832497 833225 Seq. ID No. 3190 1548 Seq. ID No. 3191 834559 834523 833408 Seq. ID No. 3192 1552 Seq. ID No. 3193 836319 836316 836029 Seq. ID No. 3194 1553a Seq. 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ID No. 3355 875908 875935 877038 Seq. ID No. 3356 1626a Seq. ID No. 3357 876984 877617 877994 Seq. ID No. 3358 1626b Seq. ID No. 3359 876984 877038 877994 Seq. ID No. 3360 1628a Seq. ID No. 3361 878218 878263 879225 Seq. ID No. 3362 1628b Seq. ID No. 3363 878218 878233 879225 Seq. ID No. 3364 1632a Seq. ID No. 3365 880585 880471 879908 Seq. ID No. 3366 1632b Seq. ID No. 3367 880585 880525 879908 Seq. ID No. 3368 1633a Seq. ID No. 3369 882546 882498 882007 Seq. ID No. 3370 1633b Seq. ID No. 3371 882546 882543 882007 Seq. ID No. 3372 1634a Seq. ID No. 3373 880656 880746 882020 Seq. ID No. 3374 1634b Seq. ID No. 3375 880656 880707 882020 Seq. ID No. 3376 1634c Seq. ID No. 3377 880656 880659 882020 Seq. ID No. 3378 1639b Seq. ID No. 3379 881983 881992 883659 Seq. ID No. 3380 1642a Seq. ID No. 3381 883922 883976 886069 Seq. ID No. 3382 1642b Seq. ID No. 3383 883922 883934 886069 Seq. ID No. 3384 1643a Seq. ID No. 3385 886023 886074 886400 Seq. ID No. 3386 1643b Seq. 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ID No. 3419 895472 895439 895203 Seq. ID No. 3420 1659a Seq. ID No. 3421 894949 896161 896691 Seq. ID No. 3422 1659b Seq. ID No. 3423 894949 895030 896691 Seq. ID No. 3424 1659c Seq. ID No. 3425 894949 894982 896691 Seq. ID No. 3426 1660b Seq. ID No. 3427 896222 896285 896725 Seq. ID No. 3428 1662a Seq. ID No. 3429 896963 896975 897847 Seq. ID No. 3430 1662b Seq. ID No. 3431 896963 896963 897847 Seq. ID No. 3432 1663 Seq. ID No. 3433 898657 898648 898361 Seq. ID No. 3434 1664 Seq. ID No. 3435 897988 898021 898602 Seq. ID No. 3436 1665a Seq. ID No. 3437 898458 898578 898913 Seq. ID No. 3438 1668 Seq. ID No. 3439 899037 899052 899945 Seq. ID No. 3440 1669 Seq. ID No. 3441 900663 900630 900307 Seq. ID No. 3442 1670a Seq. ID No. 3443 900059 900101 900757 Seq. ID No. 3444 1670b Seq. ID No. 3445 900059 900089 900757 Seq. ID No. 3446 1670c Seq. ID No. 3447 900059 900068 900757 Seq. ID No. 3448 1673a Seq. ID No. 3449 900778 902047 902286 Seq. ID No. 3450 1673b Seq. 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ID No. 3643 959998 960001 960330 Seq. ID No. 3644 1762 Seq. ID No. 3645 960400 960412 960936 Seq. ID No. 3646 1764a Seq. ID No. 3647 960937 960970 961668 Seq. ID No. 3648 1764b Seq. ID No. 3649 960937 960952 961668 Seq. ID No. 3650 1764c Seq. ID No. 3651 960937 960937 961668 Seq. ID No. 3652 1765 Seq. ID No. 3653 962620 962575 961790 Seq. ID No. 3654 1766 Seq. ID No. 3655 962761 962761 962645 Seq. ID No. 3656 1767a Seq. ID No. 3657 963674 963638 962793 Seq. ID No. 3658 1767b Seq. ID No. 3659 963674 963671 962793 Seq. ID No. 3660 1769a Seq. ID No. 3661 963809 964073 964522 Seq. ID No. 3662 1769b Seq. ID No. 3663 963809 963842 964522 Seq. ID No. 3664 1771 Seq. ID No. 3665 964635 964641 965921 Seq. ID No. 3666 1773 Seq. ID No. 3667 965922 965931 966497 Seq. ID No. 3668 1774 Seq. ID No. 3669 966556 966556 966882 Seq. ID No. 3670 1775a Seq. ID No. 3671 966897 967200 968219 Seq. ID No. 3672 1775b Seq. ID No. 3673 966897 967089 968219 Seq. ID No. 3674 1775c Seq. ID No. 3675 966897 966909 968219 Seq. ID No. 3676 1778a Seq. ID No. 3677 970818 970803 970543 Seq. ID No. 3678 1778b Seq. ID No. 3679 970818 970812 970543 Seq. ID No. 3680 1780 Seq. ID No. 3681 968216 968234 971017 Seq. ID No. 3682 1783a Seq. ID No. 3683 972121 972085 971618 Seq. ID No. 3684 1783b Seq. ID No. 3685 972121 972103 971618 Seq. ID No. 3686 1784a Seq. ID No. 3687 971018 971165 971623 Seq. ID No. 3688 1784b Seq. ID No. 3689 971018 971144 971623 Seq. ID No. 3690 1788a Seq. ID No. 3691 971657 972002 972955 Seq. ID No. 3692 1788b Seq. ID No. 3693 971657 971762 972955 Seq. ID No. 3694 1788c Seq. ID No. 3695 971657 971660 972955 Seq. ID No. 3696 1789a Seq. ID No. 3697 973047 973068 973802 Seq. ID No. 3698 1789b Seq. ID No. 3699 973047 973065 973802 Seq. ID No. 3700 1790a Seq. ID No. 3701 974447 974363 974136 Seq. ID No. 3702 1790b Seq. ID No. 3703 974447 974393 974136 Seq. ID No. 3704 1792a Seq. ID No. 3705 973813 973930 974529 Seq. ID No. 3706 1792b Seq. ID No. 3707 973813 973918 974529 Seq. ID No. 3708 1792c Seq. ID No. 3709 973813 973882 974529 Seq. ID No. 3710 1793a Seq. ID No. 3711 976354 976111 974645 Seq. ID No. 3712 1793b Seq. ID No. 3713 976354 976339 974645 Seq. ID No. 3714 1793c Seq. ID No. 3715 976354 976348 974645 Seq. ID No. 3716 1794a Seq. ID No. 3717 974942 975002 975253 Seq. ID No. 3718 1797a Seq. ID No. 3719 976552 976615 977007 Seq. ID No. 3720 1797b Seq. ID No. 3721 976552 976576 977007 Seq. ID No. 3722 1798a Seq. ID No. 3723 977119 977431 977703 Seq. ID No. 3724 1798b Seq. ID No. 3725 977119 977155 977703 Seq. ID No. 3726 1798c Seq. ID No. 3727 977119 977119 977703 Seq. ID No. 3728 1800 Seq. ID No. 3729 977713 977731 978411 Seq. ID No. 3730 1802a Seq. ID No. 3731 978665 978695 979249 Seq. ID No. 3732 1802b Seq. ID No. 3733 978665 978674 979249 Seq. ID No. 3734 1803 Seq. ID No. 3735 979246 979252 979512 Seq. ID No. 3736 1804a Seq. ID No. 3737 979506 979521 979817 Seq. ID No. 3738 1804b Seq. ID No. 3739 979506 979512 979817 Seq. ID No. 3740 1805 Seq. ID No. 3741 979818 979821 980378 Seq. ID No. 3742 1806a Seq. ID No. 3743 980320 980392 981078 Seq. ID No. 3744 1806b Seq. ID No. 3745 980320 980371 981078 Seq. ID No. 3746 1806c Seq. ID No. 3747 980320 980338 981078 Seq. ID No. 3748 1807a Seq. ID No. 3749 981100 981109 981456 Seq. ID No. 3750 1807b Seq. ID No. 3751 981100 981100 981456 Seq. ID No. 3752 1808a Seq. ID No. 3753 981441 982707 983054 Seq. ID No. 3754 1808b Seq. ID No. 3755 981441 982521 983054 Seq. ID No. 3756 1808c Seq. ID No. 3757 981441 982008 983054 Seq. ID No. 3758 1808d Seq. ID No. 3759 981441 981453 983054 Seq. ID No. 3760 1809a Seq. ID No. 3761 983069 984152 984700 Seq. ID No. 3762 1809b Seq. ID No. 3763 983069 983858 984700 Seq. ID No. 3764 1809c Seq. ID No. 3765 983069 983705 984700 Seq. ID No. 3766 1809d Seq. ID No. 3767 983069 983258 984700 Seq. ID No. 3768 1809e Seq. ID No. 3769 983069 983093 984700 Seq. ID No. 3770 1809f Seq. ID No. 3771 983069 983090 984700 Seq. ID No. 3772 1810a Seq. ID No. 3773 984753 984786 985220 Seq. ID No. 3774 1810b Seq. ID No. 3775 984753 984777 985220 Seq. ID No. 3776 1811a Seq. ID No. 3777 985498 985525 986454 Seq. ID No. 3778 1811b Seq. ID No. 3779 985498 985504 986454 Seq. ID No. 3780 1812a Seq. ID No. 3781 986785 986863 987144 Seq. ID No. 3782 1812b Seq. ID No. 3783 986785 986821 987144 Seq. ID No. 3784 1813 Seq. ID No. 3785 987852 987849 987478 Seq. ID No. 3786 1815a Seq. ID No. 3787 988694 988457 988041 Seq. ID No. 3788 1815b Seq. ID No. 3789 988694 988541 988041 Seq. ID No. 3790 1815c Seq. ID No. 3791 988694 988565 988041 Seq. ID No. 3792 1816a Seq. ID No. 3793 990681 990537 988399 Seq. ID No. 3794 1816b Seq. ID No. 3795 990681 990672 988399 Seq. ID No. 3796 1816c Seq. ID No. 3797 990681 990675 988399 Seq. ID No. 3798 1817a Seq. ID No. 3799 988113 988182 988472 Seq. ID No. 3800 1819a Seq. ID No. 3801 991399 991240 990737 Seq. ID No. 3802 1819b Seq. ID No. 3803 991399 991372 990737 Seq. ID No. 3804 1821 Seq. ID No. 3805 991399 991462 992019 Seq. ID No. 3806 1822 Seq. ID No. 3807 992670 992622 992392 Seq. ID No. 3808 1823a Seq. ID No. 3809 992081 992093 992791 Seq. ID No. 3810 1823b Seq. ID No. 3811 992081 992084 992791 Seq. ID No. 3812 1825 Seq. ID No. 3813 993363 993384 993830 Seq. ID No. 3814 1826a Seq. ID No. 3815 994009 994021 994287 Seq. ID No. 3816 1826b Seq. ID No. 3817 994009 994015 994287 Seq. ID No. 3818 1828 Seq. ID No. 3819 993831 993834 994970 Seq. ID No. 3820 1830a Seq. ID No. 3821 995061 995355 995987 Seq. ID No. 3822 1830b Seq. ID No. 3823 995061 995127 995987 Seq. ID No. 3824 1833 Seq. ID No. 3825 996148 996148 997719 Seq. ID No. 3826 1834 Seq. ID No. 3827 998067 998067 997864 Seq. ID No. 3828 1835 Seq. ID No. 3829 998280 998280 998462 Seq. ID No. 3830 1836a Seq. ID No. 3831 998407 998452 999252 Seq. ID No. 3832 1836b Seq. ID No. 3833 998407 998437 999252 Seq. ID No. 3834 1837 Seq. ID No. 3835 999249 999264 999962 Seq. ID No. 3836 1838a Seq. ID No. 3837 999984 1000437 1001729 Seq. ID No. 3838 1838b Seq. ID No. 3839 999984 1000410 1001729 Seq. ID No. 3840 1838c Seq. ID No. 3841 999984 1000026 1001729 Seq. ID No. 3842 1838d Seq. ID No. 3843 999984 999993 1001729 Seq. ID No. 3844 1839a Seq. ID No. 3845 1001786 1001882 1002862 Seq. ID No. 3846 1839b Seq. ID No. 3847 1001786 1001852 1002862 Seq. ID No. 3848 1842a Seq. ID No. 3849 1003007 1004168 1004401 Seq. ID No. 3850 1842b Seq. ID No. 3851 1003007 1003763 1004401 Seq. ID No. 3852 1842c Seq. ID No. 3853 1003007 1003511 1004401 Seq. ID No. 3854 1842d Seq. ID No. 3855 1003007 1003013 1004401 Seq. ID No. 3856 1843 Seq. ID No. 3857 1004418 1004421 1005749 Seq. ID No. 3858 1845a Seq. ID No. 3859 1008055 1007122 1006469 Seq. ID No. 3860 1845b Seq. ID No. 3861 1008055 1007620 1006469 Seq. ID No. 3862 1845c Seq. ID No. 3863 1008055 1008037 1006469 Seq. ID No. 3864 1848a Seq. ID No. 3865 1009315 1009012 1008188 Seq. ID No. 3866 1848b Seq. ID No. 3867 1009315 1009315 1008188 Seq. ID No. 3868 1850a Seq. ID No. 3869 1009477 1009501 1010796 Seq. ID No. 3870 1850b Seq. ID No. 3871 1009477 1009495 1010796 Seq. ID No. 3872 1850c Seq. ID No. 3873 1009477 1009486 1010796 Seq. ID No. 3874 1853a Seq. ID No. 3875 1010827 1010860 1011777 Seq. ID No. 3876 1853b Seq. ID No. 3877 1010827 1010830 1011777 Seq. ID No. 3878 1854a Seq. ID No. 3879 1011872 1011941 1012564 Seq. ID No. 3880 1854b Seq. ID No. 3881 1011872 1011875 1012564 Seq. ID No. 3882 1855 Seq. ID No. 3883 1012793 1012808 1013707 Seq. ID No. 3884 1856 Seq. ID No. 3885 1013934 1014024 1014491 Seq. ID No. 3886 1857a Seq. ID No. 3887 1016563 1015273 1014593 Seq. ID No. 3888 1857b Seq. ID No. 3889 1016563 1016080 1014593 Seq. ID No. 3890 1857c Seq. ID No. 3891 1016563 1016137 1014593 Seq. ID No. 3892 1857d Seq. ID No. 3893 1016563 1016536 1014593 Seq. ID No. 3894 1858 Seq. ID No. 3895 1015131 1015131 1014907 Seq. ID No. 3896 1859 Seq. ID No. 3897 1016974 1016971 1016564 Seq. ID No. 3898 1861a Seq. ID No. 3899 1017158 1017200 1019077 Seq. ID No. 3900 1861b Seq. ID No. 3901 1017158 1017173 1019077 Seq. ID No. 3902 1862a Seq. ID No. 3903 1019736 1019589 1019356 Seq. ID No. 3904 1863a Seq. ID No. 3905 1019023 1019089 1019583 Seq. ID No. 3906 1863b Seq. ID No. 3907 1019023 1019050 1019583 Seq. ID No. 3908 1864a Seq. ID No. 3909 1019384 1019564 1019725 Seq. ID No. 3910 1865a Seq. ID No. 3911 1020661 1020484 1019975 Seq. ID No. 3912 1865b Seq. ID No. 3913 1020661 1020583 1019975 Seq. ID No. 3914 1868 Seq. ID No. 3915 1020702 1020720 1021364 Seq. ID No. 3916 1869 Seq. ID No. 3917 1021387 1021423 1021665 Seq. ID No. 3918 1870 Seq. ID No. 3919 1021696 1021726 1022442 Seq. ID No. 3920 1873a Seq. ID No. 3921 1022670 1022817 1024157 Seq. ID No. 3922 1873b Seq. ID No. 3923 1022670 1022691 1024157 Seq. ID No. 3924 1873c Seq. ID No. 3925 1022670 1022685 1024157 Seq. ID No. 3926 1875b Seq. ID No. 3927 1024158 1024332 1024784 Seq. ID No. 3928 1875c Seq. ID No. 3929 1024158 1024176 1024784 Seq. ID No. 3930 1877a Seq. ID No. 3931 1024785 1024875 1025720 Seq. ID No. 3932 1877b Seq. ID No. 3933 1024785 1024839 1025720 Seq. ID No. 3934 1878 Seq. ID No. 3935 1025721 1025727 1026500 Seq. ID No. 3936 1879 Seq. ID No. 3937 1026737 1026746 1027618 Seq. ID No. 3938 1882 Seq. ID No. 3939 1029775 1029730 1029149 Seq. ID No. 3940 1884 Seq. ID No. 3941 1027658 1027664 1029772 Seq. ID No. 3942 1886 Seq. ID No. 3943 1030310 1030322 1031617 Seq. ID No. 3944 1887 Seq. ID No. 3945 1032244 1032274 1033614 Seq. ID No. 3946 1888a Seq. ID No. 3947 1033590 1033638 1034795 Seq. ID No. 3948 1888b Seq. ID No. 3949 1033590 1033605 1034795 Seq. ID No. 3950 1890 Seq. ID No. 3951 1035321 1035333 1036628 Seq. ID No. 3952 1891a Seq. ID No. 3953 1036778 1036790 1037686 Seq. ID No. 3954 1891b Seq. ID No. 3955 1036778 1036781 1037686 Seq. ID No. 3956 1893 Seq. ID No. 3957 1037696 1037708 1038250 Seq. ID No. 3958 1894c Seq. ID No. 3959 1039058 1039037 1038525 Seq. ID No. 3960 1895 Seq. ID No. 3961 1039206 1039179 1038955 Seq. ID No. 3962 1896a Seq. ID No. 3963 1039673 1039535 1039275 Seq. ID No. 3964 1896b Seq. ID No. 3965 1039673 1039670 1039275 Seq. ID No. 3966 1897a Seq. ID No. 3967 1038235 1038385 1039677 Seq. ID No. 3968 1897b Seq. ID No. 3969 1038235 1038367 1039677 Seq. ID No. 3970 1897c Seq. ID No. 3971 1038235 1038247 1039677 Seq. ID No. 3972 1898a Seq. ID No. 3973 1040455 1040092 1039814 Seq. ID No. 3974 1898b Seq. ID No. 3975 1040455 1040443 1039814 Seq. ID No. 3976 1899 Seq. ID No. 3977 1039856 1039856 1039984 Seq. ID No. 3978 1900 Seq. ID No. 3979 1040697 1040739 1041041 Seq. ID No. 3980 1902a Seq. ID No. 3981 1040639 1040720 1042606 Seq. ID No. 3982 1902b Seq. ID No. 3983 1040639 1040645 1042606 Seq. ID No. 3984 1907 Seq. ID No. 3985 1042729 1042732 1045191 Seq. ID No. 3986 1912 Seq. ID No. 3987 1045328 1045331 1047583 Seq. ID No. 3988 1915a Seq. ID No. 3989 1047614 1047626 1048372 Seq. ID No. 3990 1915b Seq. ID No. 3991 1047614 1047620 1048372 Seq. ID No. 3992 1916 Seq. ID No. 3993 1048741 1048741 1048932 Seq. ID No. 3994 1917a Seq. ID No. 3995 1049809 1049785 1049450 Seq. ID No. 3996 1917b Seq. ID No. 3997 1049809 1049806 1049450 Seq. ID No. 3998 1918b Seq. ID No. 3999 1049037 1049160 1049855 Seq. ID No. 4000 1918c Seq. ID No. 4001 1049037 1049073 1049855 Seq. ID No. 4002 1918d Seq. ID No. 4003 1049037 1049058 1049855 Seq. ID No. 4004 1919a Seq. ID No. 4005 1050015 1050093 1050395 Seq. ID No. 4006 1919b Seq. ID No. 4007 1050015 1050060 1050395 Seq. ID No. 4008 1919c Seq. ID No. 4009 1050015 1050033 1050395 Seq. ID No. 4010 1923a Seq. ID No. 4011 1050906 1050942 1051274 Seq. ID No. 4012 1923b Seq. ID No. 4013 1050906 1050921 1051274 Seq. ID No. 4014 1925 Seq. ID No. 4015 1051259 1051301 1053043 Seq. ID No. 4016 1926 Seq. ID No. 4017 1056054 1056039 1053739 Seq. ID No. 4018 1927a Seq. ID No. 4019 1057220 1056728 1056186 Seq. ID No. 4020 1927b Seq. ID No. 4021 1057220 1057217 1056186 Seq. ID No. 4022 1930 Seq. ID No. 4023 1057377 1057383 1058411 Seq. ID No. 4024 1931a Seq. ID No. 4025 1059508 1058830 1058501 Seq. ID No. 4026 1931b Seq. ID No. 4027 1059508 1058938 1058501 Seq. ID No. 4028 1931c Seq. ID No. 4029 1059508 1059370 1058501 Seq. ID No. 4030 1932 Seq. ID No. 4031 1059744 1059726 1059454 Seq. ID No. 4032 1933a Seq. ID No. 4033 1060398 1060266 1059748 Seq. ID No. 4034 1933b Seq. ID No. 4035 1060398 1060398 1059748 Seq. ID No. 4036 1934 Seq. ID No. 4037 1061142 1061124 1060399 Seq. ID No. 4038 1936 Seq. ID No. 4039 1062327 1062327 1061245 Seq. ID No. 4040 1937a Seq. ID No. 4041 1063629 1062585 1062328 Seq. ID No. 4042 1937b Seq. ID No. 4043 1063629 1062750 1062328 Seq. ID No. 4044 1937c Seq. ID No. 4045 1063629 1062804 1062328 Seq. ID No. 4046 1937d Seq. ID No. 4047 1063629 1063587 1062328 Seq. ID No. 4048 1937e Seq. ID No. 4049 1063629 1063596 1062328 Seq. ID No. 4050 1939a Seq. ID No. 4051 1064617 1064539 1063607 Seq. ID No. 4052 1939b Seq. ID No. 4053 1064617 1064596 1063607 Seq. ID No. 4054 1939c Seq. ID No. 4055 1064617 1064614 1063607 Seq. ID No. 4056 1940 Seq. ID No. 4057 1065300 1065288 1064641 Seq. ID No. 4058 1941a Seq. ID No. 4059 1066411 1066216 1065281 Seq. ID No. 4060 1941b Seq. ID No. 4061 1066411 1066393 1065281 Seq. ID No. 4062 1942 Seq. ID No. 4063 1067113 1067026 1066649 Seq. ID No. 4064 1943a Seq. ID No. 4065 1067802 1067511 1067122 Seq. ID No. 4066 1943b Seq. ID No. 4067 1067802 1067544 1067122 Seq. ID No. 4068 1944 Seq. ID No. 4069 1067921 1067873 1067535 Seq. ID No. 4070 1946a Seq. ID No. 4071 1069576 1068571 1068113 Seq. ID No. 4072 1946b Seq. ID No. 4073 1069576 1069309 1068113 Seq. ID No. 4074 1946c Seq. ID No. 4075 1069576 1069570 1068113 Seq. ID No. 4076 1949 Seq. ID No. 4077 1069969 1069969 1069706 Seq. ID No. 4078 1950 Seq. ID No. 4079 1070524 1070500 1069970 Seq. ID No. 4080 1951a Seq. ID No. 4081 1072333 1072153 1070546 Seq. ID No. 4082 1951b Seq. ID No. 4083 1072333 1072267 1070546 Seq. ID No. 4084 1951c Seq. ID No. 4085 1072333 1072279 1070546 Seq. ID No. 4086 1951d Seq. ID No. 4087 1072333 1072321 1070546 Seq. ID No. 4088 1953 Seq. ID No. 4089 1073298 1073298 1072453 Seq. ID No. 4090 1954a Seq. ID No. 4091 1074218 1074092 1073424 Seq. ID No. 4092 1954b Seq. ID No. 4093 1074218 1074155 1073424 Seq. ID No. 4094 1954c Seq. ID No. 4095 1074218 1074167 1073424 Seq. ID No. 4096 1956 Seq. ID No. 4097 1074927 1074882 1074442 Seq. ID No. 4098 1957 Seq. ID No. 4099 1075766 1075754 1074945 Seq. ID No. 4100 1958a Seq. ID No. 4101 1076688 1076142 1075747 Seq. ID No. 4102 1958b Seq. ID No. 4103 1076688 1076502 1075747 Seq. ID No. 4104 1958c Seq. ID No. 4105 1076688 1076646 1075747 Seq. ID No. 4106 1960a Seq. ID No. 4107 1077650 1077386 1076643 Seq. ID No. 4108 1960b Seq. ID No. 4109 1077650 1077530 1076643 Seq. ID No. 4110 1960c Seq. ID No. 4111 1077650 1077635 1076643 Seq. ID No. 4112 1961 Seq. ID No. 4113 1076360 1076369 1076734 Seq. ID No. 4114 1962a Seq. ID No. 4115 1079051 1079006 1077744 Seq. ID No. 4116 1962b Seq. ID No. 4117 1079051 1079039 1077744 Seq. ID No. 4118 1965a Seq. ID No. 4119 1080385 1080358 1079804 Seq. ID No. 4120 1965b Seq. ID No. 4121 1080385 1080367 1079804 Seq. ID No. 4122 1966 Seq. ID No. 4123 1080971 1080932 1080441 Seq. ID No. 4124 1967 Seq. ID No. 4125 1081519 1081510 1081103 Seq. ID No. 4126 1968 Seq. ID No. 4127 1082563 1082482 1081568 Seq. ID No. 4128 1969 Seq. ID No. 4129 1082949 1082946 1082479 Seq. ID No. 4130 1970a Seq. ID No. 4131 1083034 1083196 1083726 Seq. ID No. 4132 1970b Seq. ID No. 4133 1083034 1083067 1083726 Seq. ID No. 4134 1972 Seq. ID No. 4135 1084033 1084045 1084338 Seq. ID No. 4136 1973 Seq. ID No. 4137 1083717 1083723 1084562 Seq. ID No. 4138 1976 Seq. ID No. 4139 1085958 1085958 1085671 Seq. ID No. 4140 1977a Seq. ID No. 4141 1084534 1084552 1085925 Seq. ID No. 4142 1977b Seq. ID No. 4143 1084534 1084540 1085925 Seq. ID No. 4144 1977c Seq. ID No. 4145 1084534 1084534 1085925 Seq. ID No. 4146 1979a Seq. ID No. 4147 1090104 1089960 1086301 Seq. ID No. 4148 1979b Seq. ID No. 4149 1090104 1090077 1086301 Seq. ID No. 4150 1980a Seq. ID No. 4151 1088858 1088837 1088577 Seq. ID No. 4152 1980b Seq. ID No. 4153 1088858 1088855 1088577 Seq. ID No. 4154 1981 Seq. ID No. 4155 1089710 1089743 1090015 Seq. ID No. 4156 1982 Seq. ID No. 4157 1093702 1093678 1090049 Seq. ID No. 4158 1985a Seq. ID No. 4159 1095093 1094937 1093696 Seq. ID No. 4160 1985b Seq. ID No. 4161 1095093 1095036 1093696 Seq. ID No. 4162 1986 Seq. ID No. 4163 1096130 1096085 1094955 Seq. ID No. 4164 1987a Seq. ID No. 4165 1096803 1096599 1096072 Seq. ID No. 4166 1987b Seq. ID No. 4167 1096803 1096779 1096072 Seq. ID No. 4168 1989a Seq. ID No. 4169 1097597 1097564 1096920 Seq. ID No. 4170 1989b Seq. ID No. 4171 1097597 1097585 1096920 Seq. ID No. 4172 1989c Seq. ID No. 4173 1097597 1097588 1096920 Seq. ID No. 4174 1990a Seq. ID No. 4175 1098801 1098660 1097689 Seq. 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ID No. 4269 1124479 1124464 1124108 Seq. ID No. 4270 2036 Seq. ID No. 4271 1123137 1123161 1124852 Seq. ID No. 4272 2037 Seq. ID No. 4273 1126339 1126327 1125326 Seq. ID No. 4274 2038a Seq. ID No. 4275 1126251 1126158 1125856 Seq. ID No. 4276 2040a Seq. ID No. 4277 1125890 1125932 1126255 Seq. ID No. 4278 2042 Seq. ID No. 4279 1126698 1126698 1127249 Seq. ID No. 4280 2043b Seq. ID No. 4281 1127254 1127254 1128054 Seq. ID No. 4282 2044 Seq. ID No. 4283 1129041 1129041 1128340 Seq. ID No. 4284 2045a Seq. ID No. 4285 1128368 1128383 1128649 Seq. ID No. 4286 2045b Seq. ID No. 4287 1128368 1128371 1128649 Seq. ID No. 4288 2046a Seq. ID No. 4289 1130349 1130322 1129096 Seq. ID No. 4290 2046b Seq. ID No. 4291 1130349 1130349 1129096 Seq. ID No. 4292 2047a Seq. ID No. 4293 1131789 1131750 1130452 Seq. ID No. 4294 2047b Seq. ID No. 4295 1131789 1131762 1130452 Seq. ID No. 4296 2049c Seq. ID No. 4297 1132248 1132347 1132628 Seq. ID No. 4298 2050 Seq. ID No. 4299 1131905 1131932 1132873 Seq. 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ID No. 4393 1163111 1163090 1161267 Seq. ID No. 4394 2098b Seq. ID No. 4395 1161405 1161474 1161959 Seq. ID No. 4396 2100 Seq. ID No. 4397 1164393 1164378 1163221 Seq. ID No. 4398 2101 Seq. ID No. 4399 1164206 1164203 1163817 Seq. ID No. 4400 2104 Seq. ID No. 4401 1166334 1166304 1164466 Seq. ID No. 4402 2105 Seq. ID No. 4403 1164590 1164728 1164985 Seq. ID No. 4404 2107a Seq. ID No. 4405 1164986 1165082 1165558 Seq. ID No. 4406 2107b Seq. ID No. 4407 1164986 1165040 1165558 Seq. ID No. 4408 2109a Seq. ID No. 4409 1166983 1166947 1166375 Seq. ID No. 4410 2109b Seq. ID No. 4411 1166983 1166968 1166375 Seq. ID No. 4412 2110a Seq. ID No. 4413 1168054 1168024 1166984 Seq. ID No. 4414 2110b Seq. ID No. 4415 1168054 1168045 1166984 Seq. ID No. 4416 2110c Seq. ID No. 4417 1168054 1168048 1166984 Seq. ID No. 4418 2112a Seq. ID No. 4419 1169192 1168997 1168212 Seq. ID No. 4420 2112b Seq. ID No. 4421 1169192 1169051 1168212 Seq. ID No. 4422 2112c Seq. ID No. 4423 1169192 1169159 1168212 Seq. 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ID No. 4455 1174343 1174349 1174894 Seq. ID No. 4456 2128a Seq. ID No. 4457 1175492 1175444 1174965 Seq. ID No. 4458 2128b Seq. ID No. 4459 1175492 1175456 1174965 Seq. ID No. 4460 2133 Seq. ID No. 4461 1179995 1179938 1175604 Seq. ID No. 4462 2138a Seq. ID No. 4463 1181752 1181653 1180022 Seq. ID No. 4464 2138b Seq. ID No. 4465 1181752 1181728 1180022 Seq. ID No. 4466 2138c Seq. ID No. 4467 1181752 1181737 1180022 Seq. ID No. 4468 2140a Seq. ID No. 4469 1183087 1182526 1181753 Seq. ID No. 4470 2140b Seq. ID No. 4471 1183087 1183021 1181753 Seq. ID No. 4472 2142a Seq. ID No. 4473 1183896 1183278 1183039 Seq. ID No. 4474 2142b Seq. ID No. 4475 1183896 1183833 1183039 Seq. ID No. 4476 2144a Seq. ID No. 4477 1184612 1184585 1183848 Seq. ID No. 4478 2144b Seq. ID No. 4479 1184612 1184603 1183848 Seq. ID No. 4480 2146 Seq. ID No. 4481 1185730 1185712 1184780 Seq. ID No. 4482 2147a Seq. ID No. 4483 1186442 1185977 1185735 Seq. ID No. 4484 2147b Seq. ID No. 4485 1186442 1186334 1185735 Seq. 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ID No. 4734 2264a Seq. ID No. 4735 1244629 1244707 1244976 Seq. ID No. 4736 2264b Seq. ID No. 4737 1244629 1244662 1244976 Seq. ID No. 4738 2267 Seq. ID No. 4739 1247508 1247496 1245469 Seq. ID No. 4740 2268 Seq. ID No. 4741 1246241 1246247 1246615 Seq. ID No. 4742 2269 Seq. ID No. 4743 1249248 1249239 1247569 Seq. ID No. 4744 2270 Seq. ID No. 4745 1249629 1249626 1249264 Seq. ID No. 4746 2272 Seq. ID No. 4747 1250752 1250749 1250108 Seq. ID No. 4748 2273 Seq. ID No. 4749 1251423 1251405 1250758 Seq. ID No. 4750 2274 Seq. ID No. 4751 1252317 1252305 1251424 Seq. ID No. 4752 2275a Seq. ID No. 4753 1254354 1254258 1252318 Seq. ID No. 4754 2275b Seq. ID No. 4755 1254354 1254339 1252318 Seq. ID No. 4756 2275c Seq. ID No. 4757 1254354 1254354 1252318 Seq. ID No. 4758 2276a Seq. ID No. 4759 1255081 1254802 1254299 Seq. ID No. 4760 2276b Seq. ID No. 4761 1255081 1254958 1254299 Seq. ID No. 4762 2276c Seq. ID No. 4763 1255081 1255066 1254299 Seq. ID No. 4764 2276d Seq. ID No. 4765 1255081 1255075 1254299 Seq. ID No. 4766 2277a Seq. ID No. 4767 1256478 1256451 1255072 Seq. ID No. 4768 2277b Seq. ID No. 4769 1256478 1256463 1255072 Seq. ID No. 4770 2278a Seq. ID No. 4771 1257418 1256983 1256438 Seq. ID No. 4772 2278b Seq. ID No. 4773 1257418 1257376 1256438 Seq. ID No. 4774 2278c Seq. ID No. 4775 1257418 1257394 1256438 Seq. ID No. 4776 2278d Seq. ID No. 4777 1257418 1257403 1256438 Seq. ID No. 4778 2280 Seq. ID No. 4779 1259834 1259834 1257408 Seq. ID No. 4780 2284 Seq. ID No. 4781 1261069 1261063 1259858 Seq. ID No. 4782 2285 Seq. ID No. 4783 1261477 1261465 1261241 Seq. ID No. 4784 2286a Seq. ID No. 4785 1262148 1261971 1261465 Seq. ID No. 4786 2286b Seq. ID No. 4787 1262148 1262130 1261465 Seq. ID No. 4788 2288 Seq. ID No. 4789 1263490 1263487 1262135 Seq. ID No. 4790 2290 Seq. ID No. 4791 1264398 1264398 1263730 Seq. ID No. 4792 2291a Seq. ID No. 4793 1265817 1265784 1264405 Seq. ID No. 4794 2291b Seq. ID No. 4795 1265817 1265799 1264405 Seq. 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ID No. 4827 1274658 1274640 1273681 Seq. ID No. 4828 2309a Seq. ID No. 4829 1275133 1274938 1274654 Seq. ID No. 4830 2309b Seq. ID No. 4831 1275133 1274956 1274654 Seq. ID No. 4832 2309c Seq. ID No. 4833 1275133 1275010 1274654 Seq. ID No. 4834 2310 Seq. ID No. 4835 1275318 1275294 1275058 Seq. ID No. 4836 2311 Seq. ID No. 4837 1276504 1276489 1275308 Seq. ID No. 4838 2312a Seq. ID No. 4839 1278512 1278431 1276806 Seq. ID No. 4840 2312b Seq. ID No. 4841 1278512 1278485 1276806 Seq. ID No. 4842 2312c Seq. ID No. 4843 1278512 1278494 1276806 Seq. ID No. 4844 2314 Seq. ID No. 4845 1278600 1278633 1279616 Seq. ID No. 4846 2315 Seq. ID No. 4847 1279974 1279980 1280267 Seq. ID No. 4848 2316 Seq. ID No. 4849 1282453 1282450 1280330 Seq. ID No. 4850 2317 Seq. ID No. 4851 1280784 1280841 1281170 Seq. ID No. 4852 2320 Seq. ID No. 4853 1282272 1282278 1282565 Seq. ID No. 4854 2321a Seq. ID No. 4855 1282966 1282873 1282604 Seq. ID No. 4856 2321b Seq. ID No. 4857 1282966 1282909 1282604 Seq. ID No. 4858 2321c Seq. ID No. 4859 1282966 1282939 1282604 Seq. ID No. 4860 2322 Seq. ID No. 4861 1285049 1285034 1283040 Seq. ID No. 4862 2324 Seq. ID No. 4863 1283044 1283068 1283607 Seq. ID No. 4864 2327 Seq. ID No. 4865 1285600 1285549 1285298 Seq. ID No. 4866 2328 Seq. ID No. 4867 1286689 1286668 1285637 Seq. ID No. 4868 2329a Seq. ID No. 4869 1289009 1287596 1286658 Seq. ID No. 4870 2329b Seq. ID No. 4871 1289009 1287857 1286658 Seq. ID No. 4872 2329c Seq. ID No. 4873 1289009 1288268 1286658 Seq. ID No. 4874 2329d Seq. ID No. 4875 1289009 1288994 1286658 Seq. ID No. 4876 2330 Seq. ID No. 4877 1289504 1289489 1289010 Seq. ID No. 4878 2331 Seq. ID No. 4879 1290204 1290183 1289548 Seq. ID No. 4880 2333 Seq. ID No. 4881 1290847 1290847 1290371 Seq. ID No. 4882 2335 Seq. ID No. 4883 1291411 1291402 1290848 Seq. ID No. 4884 2336 Seq. ID No. 4885 1291822 1291732 1291412 Seq. ID No. 4886 2337b Seq. ID No. 4887 1292097 1292079 1291810 Seq. ID No. 4888 2338a Seq. ID No. 4889 1293987 1293840 1292143 Seq. ID No. 4890 2338b Seq. ID No. 4891 1293987 1293891 1292143 Seq. ID No. 4892 2338c Seq. ID No. 4893 1293987 1293972 1292143 Seq. ID No. 4894 2342a Seq. ID No. 4895 1294892 1294544 1294074 Seq. ID No. 4896 2342b Seq. ID No. 4897 1294892 1294781 1294074 Seq. ID No. 4898 2342c Seq. ID No. 4899 1294892 1294856 1294074 Seq. ID No. 4900 2344 Seq. ID No. 4901 1296464 1296425 1295013 Seq. ID No. 4902 2345 Seq. ID No. 4903 1297883 1297877 1296513 Seq. ID No. 4904 2347 Seq. ID No. 4905 1298903 1298897 1297914 Seq. ID No. 4906 2348 Seq. ID No. 4907 1300105 1300084 1298900 Seq. ID No. 4908 2349a Seq. ID No. 4909 1300346 1300391 1300954 Seq. ID No. 4910 2349b Seq. ID No. 4911 1300346 1300373 1300954 Seq. ID No. 4912 2350a Seq. ID No. 4913 1302119 1302026 1301769 Seq. ID No. 4914 2353 Seq. ID No. 4915 1301242 1301248 1302921 Seq. ID No. 4916 2354 Seq. ID No. 4917 1303618 1303603 1302971 Seq. ID No. 4918 2357 Seq. ID No. 4919 1304669 1304657 1303596 Seq. ID No. 4920 2358 Seq. ID No. 4921 1305415 1305397 1304654 Seq. ID No. 4922 2360 Seq. ID No. 4923 1306366 1306351 1306055 Seq. ID No. 4924 2361a Seq. ID No. 4925 1306811 1306532 1306110 Seq. ID No. 4926 2361b Seq. ID No. 4927 1306811 1306745 1306110 Seq. ID No. 4928 2363a Seq. ID No. 4929 1307978 1307936 1306833 Seq. ID No. 4930 2363b Seq. ID No. 4931 1307978 1307975 1306833 Seq. ID No. 4932 2365a Seq. ID No. 4933 1308165 1308219 1309355 Seq. ID No. 4934 2365b Seq. ID No. 4935 1308165 1308189 1309355 Seq. ID No. 4936 2366a Seq. ID No. 4937 1310189 1310135 1309491 Seq. ID No. 4938 2366b Seq. ID No. 4939 1310189 1310138 1309491 Seq. ID No. 4940 2367 Seq. ID No. 4941 1310796 1310793 1310128 Seq. ID No. 4942 2368 Seq. ID No. 4943 1311881 1311860 1310793 Seq. ID No. 4944 2369 Seq. ID No. 4945 1313031 1313028 1311862 Seq. ID No. 4946 2370 Seq. ID No. 4947 1313797 1313788 1313054 Seq. ID No. 4948 2371a Seq. ID No. 4949 1312950 1313103 1313339 Seq. ID No. 4950 2372 Seq. ID No. 4951 1313340 1313382 1313705 Seq. ID No. 4952 2373 Seq. ID No. 4953 1314523 1314511 1313798 Seq. ID No. 4954 2374a Seq. ID No. 4955 1315386 1315314 1314508 Seq. ID No. 4956 2374b Seq. ID No. 4957 1315386 1315377 1314508 Seq. ID No. 4958 2376 Seq. ID No. 4959 1316374 1316374 1315394 Seq. ID No. 4960 2377a Seq. ID No. 4961 1317653 1317590 1316367 Seq. ID No. 4962 2377b Seq. ID No. 4963 1317653 1317650 1316367 Seq. ID No. 4964 2378 Seq. ID No. 4965 1318340 1318334 1318038 Seq. ID No. 4966 2379a Seq. ID No. 4967 1318807 1318741 1318331 Seq. ID No. 4968 2379b Seq. ID No. 4969 1318807 1318750 1318331 Seq. ID No. 4970 2380 Seq. ID No. 4971 1319037 1319019 1318747 Seq. ID No. 4972 2381 Seq. ID No. 4973 1320232 1320205 1319264 Seq. ID No. 4974 2382c Seq. ID No. 4975 1319889 1319790 1319509 Seq. ID No. 4976 2384a Seq. ID No. 4977 1322997 1322961 1320310 Seq. ID No. 4978 2384b Seq. ID No. 4979 1322997 1322982 1320310 Seq. ID No. 4980 2386b Seq. ID No. 4981 1322660 1322696 1323103 Seq. ID No. 4982 2386c Seq. ID No. 4983 1322660 1322675 1323103 Seq. ID No. 4984 2387 Seq. ID No. 4985 1324321 1324225 1323305 Seq. ID No. 4986 2390 Seq. ID No. 4987 1324802 1324754 1324458 Seq. ID No. 4988 2391 Seq. ID No. 4989 1324273 1324294 1325208 Seq. ID No. 4990 2392 Seq. ID No. 4991 1327683 1327665 1325251 Seq. ID No. 4992 2394 Seq. ID No. 4993 1325873 1325882 1326148 Seq. ID No. 4994 2395 Seq. ID No. 4995 1328666 1328639 1327779 Seq. ID No. 4996 2396 Seq. ID No. 4997 1329927 1329906 1328779 Seq. ID No. 4998 2397 Seq. ID No. 4999 1328731 1328752 1329045 Seq. ID No. 5000 2398 Seq. ID No. 5001 1330390 1330381 1330037 Seq. ID No. 5002 2399a Seq. ID No. 5003 1331563 1331224 1330391 Seq. ID No. 5004 2399b Seq. ID No. 5005 1331563 1331488 1330391 Seq. ID No. 5006 2399c Seq. ID No. 5007 1331563 1331542 1330391 Seq. ID No. 5008 2401 Seq. ID No. 5009 1333918 1333894 1331564 Seq. ID No. 5010 2402a Seq. ID No. 5011 1334374 1334266 1334003 Seq. ID No. 5012 2402b Seq. ID No. 5013 1334374 1334305 1334003 Seq. ID No. 5014 2403a Seq. ID No. 5015 1333974 1334010 1335254 Seq. ID No. 5016 2403b Seq. ID No. 5017 1333974 1333986 1335254 Seq. ID No. 5018 2404a Seq. ID No. 5019 1337114 1336970 1335393 Seq. ID No. 5020 2404b Seq. ID No. 5021 1337114 1337108 1335393 Seq. ID No. 5022 2407a Seq. ID No. 5023 1336219 1336225 1336524 Seq. ID No. 5024 2409a Seq. ID No. 5025 1337582 1337615 1338046 Seq. ID No. 5026 2409b Seq. ID No. 5027 1337582 1337606 1338046 Seq. ID No. 5028 2410 Seq. ID No. 5029 1339429 1339369 1338176 Seq. ID No. 5030 2412 Seq. ID No. 5031 1339044 1339017 1338787 Seq. ID No. 5032 2413a Seq. ID No. 5033 1338351 1338411 1338818 Seq. ID No. 5034 2413b Seq. ID No. 5035 1338351 1338357 1338818 Seq. ID No. 5036 2415a Seq. ID No. 5037 1339712 1339586 1339392 Seq. ID No. 5038 2415b Seq. ID No. 5039 1339712 1339688 1339392 Seq. ID No. 5040 2416b Seq. ID No. 5041 1338897 1338969 1339433 Seq. ID No. 5042 2416c Seq. ID No. 5043 1338897 1338915 1339433 Seq. ID No. 5044 2417a Seq. ID No. 5045 1340413 1340371 1339583 Seq. ID No. 5046 2417b Seq. ID No. 5047 1340413 1340398 1339583 Seq. ID No. 5048 2418a Seq. ID No. 5049 1340847 1340808 1340524 Seq. ID No. 5050 2418b Seq. ID No. 5051 1340847 1340817 1340524 Seq. ID No. 5052 2420 Seq. ID No. 5053 1341166 1341157 1340795 Seq. ID No. 5054 2421 Seq. ID No. 5055 1341520 1341478 1341170 Seq. ID No. 5056 2422b Seq. ID No. 5057 1342395 1342347 1341700 Seq. ID No. 5058 2422c Seq. ID No. 5059 1342395 1342395 1341700 Seq. ID No. 5060 2423a Seq. ID No. 5061 1343009 1342928 1342413 Seq. ID No. 5062 2423b Seq. ID No. 5063 1343009 1342994 1342413 Seq. ID No. 5064 2424a Seq. ID No. 5065 1343829 1343793 1342930 Seq. ID No. 5066 2424b Seq. ID No. 5067 1343829 1343799 1342930 Seq. ID No. 5068 2424c Seq. ID No. 5069 1343829 1343817 1342930 Seq. ID No. 5070 2426 Seq. ID No. 5071 1344336 1344336 1344130 Seq. ID No. 5072 2428a Seq. ID No. 5073 1344573 1344774 1345985 Seq. ID No. 5074 2428b Seq. 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ID No. 5106 2449a Seq. ID No. 5107 1355925 1355691 1355272 Seq. ID No. 5108 2449b Seq. ID No. 5109 1355925 1355877 1355272 Seq. ID No. 5110 2451 Seq. ID No. 5111 1356746 1356734 1356105 Seq. ID No. 5112 2452 Seq. ID No. 5113 1356996 1357029 1358138 Seq. ID No. 5114 2453 Seq. ID No. 5115 1359295 1359286 1358234 Seq. ID No. 5116 2455 Seq. ID No. 5117 1360072 1360054 1359296 Seq. ID No. 5118 2456a Seq. ID No. 5119 1361028 1360605 1360051 Seq. ID No. 5120 2456b Seq. ID No. 5121 1361028 1360677 1360051 Seq. ID No. 5122 2456c Seq. ID No. 5123 1361028 1360941 1360051 Seq. ID No. 5124 2456d Seq. ID No. 5125 1361028 1361013 1360051 Seq. ID No. 5126 2456e Seq. ID No. 5127 1361028 1361025 1360051 Seq. ID No. 5128 2458a Seq. ID No. 5129 1362001 1361608 1361003 Seq. ID No. 5130 2458b Seq. ID No. 5131 1362001 1361680 1361003 Seq. ID No. 5132 2458c Seq. ID No. 5133 1362001 1361764 1361003 Seq. ID No. 5134 2458d Seq. ID No. 5135 1362001 1361767 1361003 Seq. ID No. 5136 2458e Seq. ID No. 5137 1362001 1361854 1361003 Seq. ID No. 5138 2458f Seq. ID No. 5139 1362001 1361983 1361003 Seq. ID No. 5140 2458g Seq. ID No. 5141 1362001 1361986 1361003 Seq. ID No. 5142 2461a Seq. ID No. 5143 1363565 1363550 1362201 Seq. ID No. 5144 2461b Seq. ID No. 5145 1363565 1363556 1362201 Seq. ID No. 5146 2462a Seq. ID No. 5147 1364408 1364270 1363584 Seq. ID No. 5148 2462b Seq. ID No. 5149 1364408 1364294 1363584 Seq. ID No. 5150 2463a Seq. ID No. 5151 1363279 1363366 1363731 Seq. ID No. 5152 2464 Seq. ID No. 5153 1364536 1364536 1364309 Seq. ID No. 5154 2465a Seq. ID No. 5155 1365094 1365082 1364537 Seq. ID No. 5156 2465b Seq. ID No. 5157 1365094 1365094 1364537 Seq. ID No. 5158 2468a Seq. ID No. 5159 1365781 1365751 1365422 Seq. ID No. 5160 2468b Seq. ID No. 5161 1365781 1365775 1365422 Seq. ID No. 5162 2469a Seq. ID No. 5163 1365183 1365474 1365908 Seq. ID No. 5164 2469b Seq. ID No. 5165 1365183 1365204 1365908 Seq. ID No. 5166 2470 Seq. ID No. 5167 1367011 1367011 1366664 Seq. 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ID No. 5230 2501b Seq. ID No. 5231 1384292 1384280 1383324 Seq. ID No. 5232 2504a Seq. ID No. 5233 1384748 1384718 1384293 Seq. ID No. 5234 2504b Seq. ID No. 5235 1384748 1384724 1384293 Seq. ID No. 5236 2505 Seq. ID No. 5237 1385365 1385353 1384976 Seq. ID No. 5238 2506 Seq. ID No. 5239 1386567 1386534 1385977 Seq. ID No. 5240 2507b Seq. ID No. 5241 1387792 1387783 1386590 Seq. ID No. 5242 2507c Seq. ID No. 5243 1387792 1387792 1386590 Seq. ID No. 5244 2510 Seq. ID No. 5245 1388536 1388533 1387814 Seq. ID No. 5246 2512c Seq. ID No. 5247 1388904 1388901 1388533 Seq. ID No. 5248 2513a Seq. ID No. 5249 1389534 1389486 1388905 Seq. ID No. 5250 2513b Seq. ID No. 5251 1389534 1389516 1388905 Seq. ID No. 5252 2513c Seq. ID No. 5253 1389534 1389525 1388905 Seq. ID No. 5254 2514 Seq. ID No. 5255 1390141 1390135 1389491 Seq. ID No. 5256 2515 Seq. ID No. 5257 1390451 1390451 1390137 Seq. ID No. 5258 2516a Seq. ID No. 5259 1391642 1391396 1390482 Seq. ID No. 5260 2516b Seq. ID No. 5261 1391642 1391627 1390482 Seq. ID No. 5262 2517a Seq. ID No. 5263 1392251 1392185 1391643 Seq. ID No. 5264 2517b Seq. ID No. 5265 1392251 1392248 1391643 Seq. ID No. 5266 2518a Seq. ID No. 5267 1391575 1391770 1392045 Seq. ID No. 5268 2519a Seq. ID No. 5269 1392498 1392462 1392199 Seq. ID No. 5270 2519b Seq. ID No. 5271 1392498 1392492 1392199 Seq. ID No. 5272 2520a Seq. ID No. 5273 1394487 1394379 1392658 Seq. ID No. 5274 2520b Seq. ID No. 5275 1394487 1394400 1392658 Seq. ID No. 5276 2520c Seq. ID No. 5277 1394487 1394469 1392658 Seq. ID No. 5278 2520d Seq. ID No. 5279 1394487 1394487 1392658 Seq. ID No. 5280 2521 Seq. ID No. 5281 1393493 1393499 1393756 Seq. ID No. 5282 2523 Seq. ID No. 5283 1394650 1394647 1394381 Seq. ID No. 5284 2525a Seq. ID No. 5285 1396526 1396475 1396092 Seq. ID No. 5286 2525b Seq. ID No. 5287 1396526 1396490 1396092 Seq. ID No. 5288 2527a Seq. ID No. 5289 1394878 1395148 1397184 Seq. ID No. 5290 2527b Seq. ID No. 5291 1394878 1394953 1397184 Seq. ID No. 5292 2528a Seq. ID No. 5293 1399138 1398754 1397267 Seq. ID No. 5294 2528b Seq. ID No. 5295 1399138 1398850 1397267 Seq. ID No. 5296 2528c Seq. ID No. 5297 1399138 1398922 1397267 Seq. ID No. 5298 2528d Seq. ID No. 5299 1399138 1398961 1397267 Seq. ID No. 5300 2532b Seq. ID No. 5301 1397745 1397808 1398275 Seq. ID No. 5302 2532c Seq. ID No. 5303 1397745 1397772 1398275 Seq. ID No. 5304 2534 Seq. ID No. 5305 1399875 1399866 1398979 Seq. ID No. 5306 2535a Seq. ID No. 5307 1400680 1400668 1399847 Seq. ID No. 5308 2535b Seq. ID No. 5309 1400680 1400674 1399847 Seq. ID No. 5310 2538 Seq. ID No. 5311 1401349 1401310 1400681 Seq. ID No. 5312 2541 Seq. ID No. 5313 1401366 1401387 1401971 Seq. ID No. 5314 2542a Seq. ID No. 5315 1402014 1402296 1402676 Seq. ID No. 5316 2542b Seq. ID No. 5317 1402014 1402077 1402676 Seq. ID No. 5318 2542c Seq. ID No. 5319 1402014 1402062 1402676 Seq. ID No. 5320 2543 Seq. ID No. 5321 1403760 1403730 1403266 Seq. ID No. 5322 2544 Seq. ID No. 5323 1403203 1403254 1404255 Seq. ID No. 5324 2545 Seq. ID No. 5325 1404256 1404304 1404855 Seq. ID No. 5326 2546 Seq. ID No. 5327 1405305 1405302 1405021 Seq. ID No. 5328 2547b Seq. ID No. 5329 1406040 1406031 1405459 Seq. ID No. 5330 2547c Seq. ID No. 5331 1406040 1406037 1405459 Seq. ID No. 5332 2548a Seq. ID No. 5333 1404971 1405037 1405978 Seq. ID No. 5334 2548b Seq. ID No. 5335 1404971 1404995 1405978 Seq. ID No. 5336 2549 Seq. ID No. 5337 1405979 1405988 1406572 Seq. ID No. 5338 2550b Seq. ID No. 5339 1406454 1406559 1406936 Seq. ID No. 5340 2550c Seq. ID No. 5341 1406454 1406538 1406936 Seq. ID No. 5342 2550e Seq. ID No. 5343 1406454 1406469 1406936 Seq. ID No. 5344 2552 Seq. ID No. 5345 1407012 1407042 1408169 Seq. ID No. 5346 2553 Seq. ID No. 5347 1408922 1408922 1408764 Seq. ID No. 5348 2554a Seq. ID No. 5349 1410070 1410022 1409012 Seq. ID No. 5350 2554b Seq. ID No. 5351 1410070 1410031 1409012 Seq. ID No. 5352 2555a Seq. ID No. 5353 1410981 1410666 1410037 Seq. ID No. 5354 2555b Seq. ID No. 5355 1410981 1410930 1410037 Seq. ID No. 5356 2555c Seq. ID No. 5357 1410981 1410954 1410037 Seq. ID No. 5358 2555d Seq. ID No. 5359 1410981 1410960 1410037 Seq. ID No. 5360 2558a Seq. ID No. 5361 1411225 1411165 1410899 Seq. ID No. 5362 2558b Seq. ID No. 5363 1411225 1411183 1410899 Seq. ID No. 5364 2559 Seq. ID No. 5365 1411808 1411841 1413085 Seq. ID No. 5366 2561 Seq. ID No. 5367 1413552 1413567 1414415 Seq. ID No. 5368 2562a Seq. ID No. 5369 1414348 1414450 1414695 Seq. ID No. 5370 2562c Seq. ID No. 5371 1414348 1414396 1414695 Seq. ID No. 5372 2563 Seq. ID No. 5373 1416663 1416645 1414831 Seq. ID No. 5374 2564a Seq. ID No. 5375 1417575 1417422 1416748 Seq. ID No. 5376 2564b Seq. ID No. 5377 1417575 1417524 1416748 Seq. ID No. 5378 2564c Seq. ID No. 5379 1417575 1417533 1416748 Seq. ID No. 5380 2564d Seq. ID No. 5381 1417575 1417569 1416748 Seq. ID No. 5382 2566 Seq. ID No. 5383 1418729 1418708 1417590 Seq. ID No. 5384 2567a Seq. ID No. 5385 1419622 1419307 1418843 Seq. ID No. 5386 2567b Seq. ID No. 5387 1419622 1419610 1418843 Seq. ID No. 5388 2568 Seq. ID No. 5389 1420782 1420740 1419607 Seq. ID No. 5390 2572 Seq. ID No. 5391 1421908 1421875 1420760 Seq. ID No. 5392 2573 Seq. ID No. 5393 1422663 1422660 1421995 Seq. ID No. 5394 2575 Seq. ID No. 5395 1423311 1423263 1422889 Seq. ID No. 5396 2576 Seq. ID No. 5397 1424366 1424318 1423299 Seq. ID No. 5398 2578 Seq. ID No. 5399 1424941 1424926 1424564 Seq. ID No. 5400 2579b Seq. ID No. 5401 1425765 1425729 1425178 Seq. ID No. 5402 2581 Seq. ID No. 5403 1426786 1426756 1425986 Seq. ID No. 5404 2582a Seq. ID No. 5405 1427718 1427607 1426879 Seq. ID No. 5406 2582b Seq. ID No. 5407 1427718 1427694 1426879 Seq. ID No. 5408 2582c Seq. ID No. 5409 1427718 1427712 1426879 Seq. ID No. 5410 2585 Seq. ID No. 5411 1429438 1429423 1427699 Seq. ID No. 5412 2587a Seq. ID No. 5413 1429982 1429652 1429425 Seq. ID No. 5414 2587b Seq. ID No. 5415 1429982 1429982 1429425 Seq. ID No. 5416 2588 Seq. ID No. 5417 1430858 1430852 1429983 Seq. ID No. 5418 2589 Seq. ID No. 5419 1433411 1433399 1431450 Seq. ID No. 5420 2591 Seq. ID No. 5421 1434679 1434667 1433714 Seq. ID No. 5422 2592 Seq. ID No. 5423 1435611 1435470 1434667 Seq. ID No. 5424 2593a Seq. ID No. 5425 1436075 1435949 1435482 Seq. ID No. 5426 2593b Seq. ID No. 5427 1436075 1436042 1435482 Seq. ID No. 5428 2594a Seq. ID No. 5429 1436529 1436517 1436059 Seq. ID No. 5430 2594b Seq. ID No. 5431 1436529 1436526 1436059 Seq. ID No. 5432 2596 Seq. ID No. 5433 1437374 1437374 1436709 Seq. ID No. 5434 2597a Seq. ID No. 5435 1438188 1437930 1437334 Seq. ID No. 5436 2597b Seq. ID No. 5437 1438188 1438107 1437334 Seq. ID No. 5438 2597c Seq. ID No. 5439 1438188 1438158 1437334 Seq. ID No. 5440 2598 Seq. ID No. 5441 1440874 1440859 1438196 Seq. ID No. 5442 2602 Seq. ID No. 5443 1442399 1442396 1441065 Seq. ID No. 5444 2605a Seq. ID No. 5445 1442989 1442629 1442468 Seq. ID No. 5446 2605b Seq. ID No. 5447 1442989 1442968 1442468 Seq. ID No. 5448 2606 Seq. ID No. 5449 1443636 1443591 1442983 Seq. ID No. 5450 2608 Seq. ID No. 5451 1444685 1444676 1443603 Seq. ID No. 5452 2610 Seq. ID No. 5453 1444840 1444840 1445172 Seq. ID No. 5454 2611 Seq. ID No. 5455 1445942 1445927 1445280 Seq. ID No. 5456 2613 Seq. ID No. 5457 1446810 1446789 1445992 Seq. ID No. 5458 2616a Seq. ID No. 5459 1448123 1447217 1446882 Seq. ID No. 5460 2616b Seq. ID No. 5461 1448123 1447583 1446882 Seq. ID No. 5462 2616c Seq. ID No. 5463 1448123 1447613 1446882 Seq. ID No. 5464 2616d Seq. ID No. 5465 1448123 1447805 1446882 Seq. ID No. 5466 2616e Seq. ID No. 5467 1448123 1447850 1446882 Seq. ID No. 5468 2616f Seq. ID No. 5469 1448123 1447976 1446882 Seq. ID No. 5470 2616g Seq. ID No. 5471 1448123 1448084 1446882 Seq. ID No. 5472 2616h Seq. ID No. 5473 1448123 1448093 1446882 Seq. ID No. 5474 2617a Seq. ID No. 5475 1448922 1448838 1448077 Seq. ID No. 5476 2617b Seq. ID No. 5477 1448922 1448922 1448077 Seq. 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ID No. 5509 1457511 1457484 1456576 Seq. ID No. 5510 2629a Seq. ID No. 5511 1459560 1459494 1457665 Seq. ID No. 5512 2629b Seq. ID No. 5513 1459560 1459539 1457665 Seq. ID No. 5514 2631 Seq. ID No. 5515 1458482 1458482 1458249 Seq. ID No. 5516 2632 Seq. ID No. 5517 1459307 1459322 1459567 Seq. ID No. 5518 2633a Seq. ID No. 5519 1461946 1461220 1459916 Seq. ID No. 5520 2633b Seq. ID No. 5521 1461946 1461544 1459916 Seq. ID No. 5522 2633c Seq. ID No. 5523 1461946 1461727 1459916 Seq. ID No. 5524 2633d Seq. ID No. 5525 1461946 1461778 1459916 Seq. ID No. 5526 2633e Seq. ID No. 5527 1461946 1461904 1459916 Seq. ID No. 5528 2637a Seq. ID No. 5529 1463997 1463967 1462111 Seq. ID No. 5530 2637b Seq. ID No. 5531 1463997 1463991 1462111 Seq. ID No. 5532 2642 Seq. ID No. 5533 1463789 1463825 1464121 Seq. ID No. 5534 2643a Seq. ID No. 5535 1466534 1466318 1464372 Seq. ID No. 5536 2643b Seq. ID No. 5537 1466534 1466522 1464372 Seq. ID No. 5538 2645 Seq. ID No. 5539 1467800 1467782 1466751 Seq. 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ID No. 5664 2709 Seq. ID No. 5665 1505327 1505300 1504359 Seq. ID No. 5666 2710c Seq. ID No. 5667 1504984 1504885 1504604 Seq. ID No. 5668 2712 Seq. ID No. 5669 1506916 1506898 1505546 Seq. ID No. 5670 2713 Seq. ID No. 5671 1507318 1507309 1506926 Seq. ID No. 5672 2714 Seq. ID No. 5673 1507705 1507696 1507319 Seq. ID No. 5674 2716a Seq. ID No. 5675 1508501 1508477 1507878 Seq. ID No. 5676 2716b Seq. ID No. 5677 1508501 1508486 1507878 Seq. ID No. 5678 2716c Seq. ID No. 5679 1508501 1508501 1507878 Seq. ID No. 5680 2718a Seq. ID No. 5681 1508621 1508753 1509109 Seq. ID No. 5682 2718b Seq. ID No. 5683 1508621 1508702 1509109 Seq. ID No. 5684 2718c Seq. ID No. 5685 1508621 1508624 1509109 Seq. ID No. 5686 2719a Seq. ID No. 5687 1509372 1509399 1509650 Seq. ID No. 5688 2719b Seq. ID No. 5689 1509372 1509378 1509650 Seq. ID No. 5690 2721a Seq. ID No. 5691 1509110 1509434 1510138 Seq. ID No. 5692 2721b Seq. ID No. 5693 1509110 1509143 1510138 Seq. ID No. 5694 2722a Seq. 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ID No. 5788 2758c Seq. ID No. 5789 1529611 1529497 1528613 Seq. ID No. 5790 2758d Seq. ID No. 5791 1529611 1529581 1528613 Seq. ID No. 5792 2759a Seq. ID No. 5793 1530134 1530053 1529427 Seq. ID No. 5794 2759b Seq. ID No. 5795 1530134 1530134 1529427 Seq. ID No. 5796 2760a Seq. ID No. 5797 1530993 1530369 1530127 Seq. ID No. 5798 2760b Seq. ID No. 5799 1530993 1530963 1530127 Seq. ID No. 5800 2760c Seq. ID No. 5801 1530993 1530987 1530127 Seq. ID No. 5802 2762 Seq. ID No. 5803 1531820 1531820 1531293 Seq. ID No. 5804 2763a Seq. ID No. 5805 1532723 1532576 1531821 Seq. ID No. 5806 2763b Seq. ID No. 5807 1532723 1532588 1531821 Seq. ID No. 5808 2763c Seq. ID No. 5809 1532723 1532666 1531821 Seq. ID No. 5810 2764 Seq. ID No. 5811 1533169 1533145 1532774 Seq. ID No. 5812 2765b Seq. ID No. 5813 1533695 1533587 1533045 Seq. ID No. 5814 2765c Seq. ID No. 5815 1533695 1533623 1533045 Seq. ID No. 5816 2766a Seq. ID No. 5817 1535067 1535031 1533682 Seq. ID No. 5818 2766b Seq. 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ID No. 6284 2978b Seq. ID No. 6285 1666409 1666364 1666131 Seq. ID No. 6286 2979 Seq. ID No. 6287 1666051 1666126 1666689 Seq. ID No. 6288 2980a Seq. ID No. 6289 1668091 1667302 1666901 Seq. ID No. 6290 2980b Seq. ID No. 6291 1668091 1667875 1666901 Seq. ID No. 6292 2980c Seq. ID No. 6293 1668091 1667995 1666901 Seq. ID No. 6294 2980d Seq. ID No. 6295 1668091 1668028 1666901 Seq. ID No. 6296 2980e Seq. ID No. 6297 1668091 1668070 1666901 Seq. ID No. 6298 2984 Seq. ID No. 6299 1669334 1669304 1667970 Seq. ID No. 6300 2986a Seq. ID No. 6301 1670826 1670514 1669684 Seq. ID No. 6302 2986b Seq. ID No. 6303 1670826 1670706 1669684 Seq. ID No. 6304 2986c Seq. ID No. 6305 1670826 1670790 1669684 Seq. ID No. 6306 2988a Seq. ID No. 6307 1672193 1672121 1670793 Seq. ID No. 6308 2988b Seq. ID No. 6309 1672193 1672148 1670793 Seq. ID No. 6310 2988c Seq. ID No. 6311 1672193 1672154 1670793 Seq. ID No. 6312 2989 Seq. ID No. 6313 1672635 1672536 1672342 Seq. ID No. 6314 2990 Seq. ID No. 6315 1674173 1674143 1672551 Seq. ID No. 6316 2991a Seq. ID No. 6317 1675155 1674828 1674154 Seq. ID No. 6318 2991b Seq. ID No. 6319 1675155 1675080 1674154 Seq. ID No. 6320 2991c Seq. ID No. 6321 1675155 1675140 1674154 Seq. ID No. 6322 2992 Seq. ID No. 6323 1675279 1675294 1675782 Seq. ID No. 6324 2993a Seq. ID No. 6325 1676636 1676624 1675920 Seq. ID No. 6326 2993b Seq. ID No. 6327 1676636 1676627 1675920 Seq. ID No. 6328 2995a Seq. ID No. 6329 1677557 1677437 1676643 Seq. ID No. 6330 2995b Seq. ID No. 6331 1677557 1677554 1676643 Seq. ID No. 6332 2997 Seq. ID No. 6333 1677875 1677869 1677558 Seq. ID No. 6334 2998a Seq. ID No. 6335 1678755 1678617 1677862 Seq. ID No. 6336 2998b Seq. ID No. 6337 1678755 1678701 1677862 Seq. ID No. 6338 2999 Seq. ID No. 6339 1679123 1679120 1678734 Seq. ID No. 6340 3001 Seq. ID No. 6341 1680254 1680221 1679229 Seq. ID No. 6342 3003 Seq. ID No. 6343 1680586 1680574 1680245 Seq. ID No. 6344 3005 Seq. ID No. 6345 1681275 1681266 1680622 Seq. ID No. 6346 3008a Seq. ID No. 6347 1681972 1681849 1681283 Seq. ID No. 6348 3008b Seq. ID No. 6349 1681972 1681879 1681283 Seq. ID No. 6350 3008c Seq. ID No. 6351 1681972 1681882 1681283 Seq. ID No. 6352 3008d Seq. ID No. 6353 1681972 1681936 1681283 Seq. ID No. 6354 3010a Seq. ID No. 6355 1682354 1682306 1681995 Seq. ID No. 6356 3010b Seq. ID No. 6357 1682354 1682315 1681995 Seq. ID No. 6358 3012 Seq. ID No. 6359 1684114 1684102 1682330 Seq. ID No. 6360 3015 Seq. ID No. 6361 1684647 1684692 1685450 Seq. ID No. 6362 3016a Seq. ID No. 6363 1686951 1686111 1685629 Seq. ID No. 6364 3016b Seq. ID No. 6365 1686951 1686861 1685629 Seq. ID No. 6366 3016c Seq. ID No. 6367 1686951 1686930 1685629 Seq. ID No. 6368 3017 Seq. ID No. 6369 1687931 1687823 1686927 Seq. ID No. 6370 3018a Seq. ID No. 6371 1688418 1688376 1687897 Seq. ID No. 6372 3018b Seq. ID No. 6373 1688418 1688379 1687897 Seq. ID No. 6374 3020 Seq. ID No. 6375 1689300 1689261 1688419 Seq. ID No. 6376 3021 Seq. ID No. 6377 1689758 1689743 1689423 Seq. ID No. 6378 3022 Seq. ID No. 6379 1692324 1692324 1689814 Seq. ID No. 6380 3023 Seq. ID No. 6381 1689787 1689787 1690059 Seq. ID No. 6382 3024a Seq. ID No. 6383 1691465 1691537 1691806 Seq. ID No. 6384 3024b Seq. ID No. 6385 1691465 1691474 1691806 Seq. ID No. 6386 3026a Seq. ID No. 6387 1692828 1692804 1692346 Seq. ID No. 6388 3026b Seq. ID No. 6389 1692828 1692819 1692346 Seq. ID No. 6390 3028a Seq. ID No. 6391 1693823 1693703 1693047 Seq. ID No. 6392 3028b Seq. ID No. 6393 1693823 1693709 1693047 Seq. ID No. 6394 3028c Seq. ID No. 6395 1693823 1693763 1693047 Seq. ID No. 6396 3029a Seq. ID No. 6397 1694761 1694746 1693703 Seq. ID No. 6398 3029b Seq. ID No. 6399 1694761 1694758 1693703 Seq. ID No. 6400 3031a Seq. ID No. 6401 1695379 1695412 1695777 Seq. ID No. 6402 3031b Seq. ID No. 6403 1695379 1695394 1695777 Seq. ID No. 6404 3032a Seq. ID No. 6405 1696446 1696257 1696033 Seq. ID No. 6406 3032b Seq. ID No. 6407 1696446 1696299 1696033 Seq. ID No. 6408 3033a Seq. ID No. 6409 1697227 1697194 1696382 Seq. ID No. 6410 3033b Seq. ID No. 6411 1697227 1697197 1696382 Seq. ID No. 6412 3035 Seq. ID No. 6413 1697987 1697987 1697232 Seq. ID No. 6414 3037a Seq. ID No. 6415 1698709 1698781 1699263 Seq. ID No. 6416 3037b Seq. ID No. 6417 1698709 1698739 1699263 Seq. ID No. 6418 3038 Seq. ID No. 6419 1699841 1699841 1700038 Seq. ID No. 6420 3040a Seq. ID No. 6421 1701079 1700950 1700138 Seq. ID No. 6422 3040b Seq. ID No. 6423 1701079 1701079 1700138 Seq. ID No. 6424 3042a Seq. ID No. 6425 1700433 1700445 1700675 Seq. ID No. 6426 3042b Seq. ID No. 6427 1700433 1700433 1700675 Seq. ID No. 6428 3043a Seq. ID No. 6429 1701375 1701306 1701073 Seq. ID No. 6430 3043b Seq. ID No. 6431 1701375 1701324 1701073 Seq. ID No. 6432 3044 Seq. ID No. 6433 1701638 1701617 1701321 Seq. ID No. 6434 3045a Seq. ID No. 6435 1702055 1702040 1701639 Seq. ID No. 6436 3045b Seq. ID No. 6437 1702055 1702043 1701639 Seq. ID No. 6438 3048a Seq. ID No. 6439 1702494 1702383 1702033 Seq. ID No. 6440 3049a Seq. ID No. 6441 1704304 1703878 1702388 Seq. ID No. 6442 3049b Seq. ID No. 6443 1704304 1704055 1702388 Seq. ID No. 6444 3049c Seq. ID No. 6445 1704304 1704289 1702388 Seq. ID No. 6446 3051a Seq. ID No. 6447 1704655 1704649 1704305 Seq. ID No. 6448 3051b Seq. ID No. 6449 1704655 1704655 1704305 Seq. ID No. 6450 3052 Seq. ID No. 6451 1706095 1706095 1704656 Seq. ID No. 6452 3054 Seq. ID No. 6453 1705443 1705446 1705685 Seq. ID No. 6454 3055a Seq. ID No. 6455 1706386 1706362 1706096 Seq. ID No. 6456 3055b Seq. ID No. 6457 1706386 1706383 1706096 Seq. ID No. 6458 3057 Seq. ID No. 6459 1708245 1708242 1706380 Seq. ID No. 6460 3059 Seq. ID No. 6461 1709019 1709007 1708246 Seq. ID No. 6462 3060 Seq. ID No. 6463 1711662 1711659 1709020 Seq. ID No. 6464 3061 Seq. ID No. 6465 1709528 1709528 1709259 Seq. ID No. 6466 3062 Seq. ID No. 6467 1709324 1709330 1710160 Seq. ID No. 6468 3063a Seq. ID No. 6469 1710350 1710368 1710655 Seq. ID No. 6470 3063b Seq. ID No. 6471 1710350 1710365 1710655 Seq. ID No. 6472 3064b Seq. ID No. 6473 1710920 1710938 1711330 Seq. ID No. 6474 3065a Seq. ID No. 6475 1712082 1711980 1711663 Seq. ID No. 6476 3065b Seq. ID No. 6477 1712082 1711983 1711663 Seq. ID No. 6478 3066 Seq. ID No. 6479 1711331 1711412 1711774 Seq. ID No. 6480 3067 Seq. ID No. 6481 1712393 1712384 1712001 Seq. ID No. 6482 3068 Seq. ID No. 6483 1713000 1712988 1712401 Seq. ID No. 6484 3069 Seq. ID No. 6485 1713434 1713380 1712991 Seq. ID No. 6486 3071 Seq. ID No. 6487 1714045 1714003 1713764 Seq. ID No. 6488 3072a Seq. ID No. 6489 1714353 1714293 1714000 Seq. ID No. 6490 3073 Seq. ID No. 6491 1714645 1714639 1714304 Seq. ID No. 6492 3074 Seq. ID No. 6493 1715783 1715780 1714785 Seq. ID No. 6494 3075 Seq. ID No. 6495 1716350 1716335 1715784 Seq. ID No. 6496 3076 Seq. ID No. 6497 1715964 1716024 1716341 Seq. ID No. 6498 3077a Seq. ID No. 6499 1717443 1717344 1716424 Seq. ID No. 6500 3077b Seq. ID No. 6501 1717443 1717425 1716424 Seq. ID No. 6502 3077c Seq. ID No. 6503 1717443 1717443 1716424 Seq. ID No. 6504 3078 Seq. ID No. 6505 1718902 1718866 1717376 Seq. ID No. 6506 3079 Seq. ID No. 6507 1717769 1717769 1718020 Seq. ID No. 6508 3081a Seq. ID No. 6509 1720200 1720161 1718881 Seq. ID No. 6510 3081b Seq. ID No. 6511 1720200 1720179 1718881 Seq. ID No. 6512 3083c Seq. ID No. 6513 1720609 1720570 1720154 Seq. ID No. 6514 3083d Seq. ID No. 6515 1720609 1720588 1720154 Seq. ID No. 6516 3085 Seq. ID No. 6517 1720239 1720287 1720517 Seq. ID No. 6518 3086 Seq. ID No. 6519 1721223 1721223 1720798 Seq. ID No. 6520 3087a Seq. ID No. 6521 1721741 1721516 1721220 Seq. ID No. 6522 3087c Seq. ID No. 6523 1721741 1721729 1721220 Seq. ID No. 6524 3088 Seq. ID No. 6525 1722323 1722311 1721742 Seq. ID No. 6526 3089a Seq. ID No. 6527 1722579 1722534 1722301 Seq. ID No. 6528 3089b Seq. ID No. 6529 1722579 1722540 1722301 Seq. ID No. 6530 3090 Seq. ID No. 6531 1723087 1723024 1722710 Seq. ID No. 6532 3091 Seq. ID No. 6533 1723434 1723377 1723024 Seq. ID No. 6534 3092a Seq. ID No. 6535 1726056 1726017 1723726 Seq. ID No. 6536 3092b Seq. ID No. 6537 1726056 1726023 1723726 Seq. ID No. 6538 3095 Seq. ID No. 6539 1725374 1725374 1724937 Seq. ID No. 6540 3096a Seq. ID No. 6541 1724735 1724747 1724995 Seq. ID No. 6542 3096b Seq. ID No. 6543 1724735 1724738 1724995 Seq. ID No. 6544 3097 Seq. ID No. 6545 1726568 1726568 1726035 Seq. ID No. 6546 3098a Seq. ID No. 6547 1728002 1727765 1726569 Seq. ID No. 6548 3098b Seq. ID No. 6549 1728002 1727993 1726569 Seq. ID No. 6550 3098c Seq. ID No. 6551 1728002 1728002 1726569 Seq. ID No. 6552 3099 Seq. ID No. 6553 1728681 1728669 1727986 Seq. ID No. 6554 3100a Seq. ID No. 6555 1727960 1728044 1728307 Seq. ID No. 6556 3100b Seq. ID No. 6557 1727960 1728017 1728307 Seq. ID No. 6558 3101 Seq. ID No. 6559 1729161 1729158 1728682 Seq. ID No. 6560 3102 Seq. ID No. 6561 1729471 1729429 1729220 Seq. ID No. 6562 3103b Seq. ID No. 6563 1729917 1729917 1729426 Seq. ID No. 6564 3104 Seq. ID No. 6565 1730101 1730101 1729931 Seq. ID No. 6566 3105 Seq. ID No. 6567 1730458 1730434 1730144 Seq. ID No. 6568 3106 Seq. ID No. 6569 1730695 1730668 1730465 Seq. ID No. 6570 3107a Seq. ID No. 6571 1731400 1731364 1731125 Seq. ID No. 6572 3107b Seq. ID No. 6573 1731400 1731385 1731125 Seq. ID No. 6574 3108a Seq. ID No. 6575 1730751 1730838 1731467 Seq. ID No. 6576 3108b Seq. ID No. 6577 1730751 1730778 1731467 Seq. ID No. 6578 3109 Seq. ID No. 6579 1731554 1731557 1732228 Seq. ID No. 6580 3110a Seq. ID No. 6581 1732232 1732322 1732933 Seq. ID No. 6582 3110b Seq. ID No. 6583 1732232 1732244 1732933 Seq. ID No. 6584 3113 Seq. ID No. 6585 1733078 1733090 1734292 Seq. ID No. 6586 3116 Seq. ID No. 6587 1734912 1734921 1735769 Seq. ID No. 6588 3118a Seq. ID No. 6589 1735601 1735763 1736248 Seq. ID No. 6590 3118b Seq. ID No. 6591 1735601 1735673 1736248 Seq. ID No. 6592 3119a Seq. ID No. 6593 1736902 1736743 1736339 Seq. ID No. 6594 3119b Seq. ID No. 6595 1736902 1736782 1736339 Seq. ID No. 6596 3119c Seq. ID No. 6597 1736902 1736809 1736339 Seq. ID No. 6598 3119d Seq. ID No. 6599 1736902 1736848 1736339 Seq. ID No. 6600 3119e Seq. ID No. 6601 1736902 1736863 1736339 Seq. ID No. 6602 3119f Seq. ID No. 6603 1736902 1736872 1736339 Seq. ID No. 6604 3121 Seq. ID No. 6605 1736957 1736978 1737658 Seq. ID No. 6606 3122a Seq. ID No. 6607 1739218 1739212 1738022 Seq. ID No. 6608 3122b Seq. ID No. 6609 1739218 1739218 1738022 Seq. ID No. 6610 3123a Seq. ID No. 6611 1741016 1740947 1739265 Seq. ID No. 6612 3123b Seq. ID No. 6613 1741016 1741007 1739265 Seq. ID No. 6614 3124 Seq. ID No. 6615 1741584 1741551 1740970 Seq. ID No. 6616 3126 Seq. ID No. 6617 1742270 1742243 1741596 Seq. ID No. 6618 3129a Seq. ID No. 6619 1742959 1742902 1742246 Seq. ID No. 6620 3129b Seq. ID No. 6621 1742959 1742932 1742246 Seq. ID No. 6622 3131 Seq. ID No. 6623 1745173 1745167 1743977 Seq. ID No. 6624 3134a Seq. ID No. 6625 1747570 1747468 1745222 Seq. ID No. 6626 3134b Seq. ID No. 6627 1747570 1747507 1745222 Seq. ID No. 6628 3138 Seq. ID No. 6629 1748892 1748832 1747537 Seq. ID No. 6630 3140 Seq. ID No. 6631 1748324 1748327 1748560 Seq. ID No. 6632 3141 Seq. ID No. 6633 1750186 1750177 1748972 Seq. ID No. 6634 3145a Seq. ID No. 6635 1752277 1752205 1750973 Seq. ID No. 6636 3145b Seq. ID No. 6637 1752277 1752259 1750973 Seq. ID No. 6638 3145c Seq. ID No. 6639 1752277 1752274 1750973 Seq. ID No. 6640 3147a Seq. ID No. 6641 125 1754054 1752510 Seq. ID No. 6642 3147b Seq. ID No. 6643 125 122 1752510 Seq. ID No. 6644 3147c Seq. ID No. 6645 125 83 1752510 Seq. ID No. 6646 3149a Seq. ID No. 6647 7 1754326 1754123 Seq. ID No. 6648 3150a Seq. ID No. 6649 1753936 1754086 1754331 Seq. ID No. 6650 3099 Seq. ID No. 6553 1728681 1728669 1727986 Seq. ID No. 6554 3100a Seq. ID No. 6555 1727960 1728044 1728307 Seq. ID No. 6556 3100b Seq. ID No. 6557 1727960 1728017 1728307 Seq. ID No. 6558 3101 Seq. ID No. 6559 1729161 1729158 1728682 Seq. ID No. 6560 3102 Seq. ID No. 6561 1729471 1729429 1729220 Seq. ID No. 6562 3103b Seq. ID No. 6563 1729917 1729917 1729426 Seq. ID No. 6564 3104 Seq. ID No. 6565 1730101 1730101 1729931 Seq. ID No. 6566 3105 Seq. ID No. 6567 1730458 1730434 1730144 Seq. ID No. 6568 3106 Seq. ID No. 6569 1730695 1730668 1730465 Seq. ID No. 6570 3107a Seq. ID No. 6571 1731400 1731364 1731125 Seq. ID No. 6572 3107b Seq. ID No. 6573 1731400 1731385 1731125 Seq. ID No. 6574 3108a Seq. ID No. 6575 1730751 1730838 1731467 Seq. ID No. 6576 3108b Seq. ID No. 6577 1730751 1730778 1731467 Seq. ID No. 6578 3109 Seq. ID No. 6579 1731554 1731557 1732228 Seq. ID No. 6580 3110a Seq. ID No. 6581 1732232 1732322 1732933 Seq. ID No. 6582 3110b Seq. ID No. 6583 1732232 1732244 1732933 Seq. ID No. 6584 3113 Seq. ID No. 6585 1733078 1733090 1734292 Seq. ID No. 6586 3116 Seq. ID No. 6587 1734912 1734921 1735769 Seq. ID No. 6588 3118a Seq. ID No. 6589 1735601 1735763 1736248 Seq. ID No. 6590 3118b Seq. ID No. 6591 1735601 1735673 1736248 Seq. ID No. 6592 3119a Seq. ID No. 6593 1736902 1736743 1736339 Seq. ID No. 6594 3119b Seq. ID No. 6595 1736902 1736782 1736339 Seq. ID No. 6596 3119c Seq. ID No. 6597 1736902 1736809 1736339 Seq. ID No. 6598 3119d Seq. ID No. 6599 1736902 1736848 1736339 Seq. ID No. 6600 3119e Seq. ID No. 6601 1736902 1736863 1736339 Seq. ID No. 6602 3119f Seq. ID No. 6603 1736902 1736872 1736339 Seq. ID No. 6604 3121 Seq. ID No. 6605 1736957 1736978 1737658 Seq. ID No. 6606 3122a Seq. ID No. 6607 1739218 1739212 1738022 Seq. ID No. 6608 3122b Seq. ID No. 6609 1739218 1739218 1738022 Seq. ID No. 6610 3123a Seq. ID No. 6611 1741016 1740947 1739265 Seq. ID No. 6612 3123b Seq. ID No. 6613 1741016 1741007 1739265 Seq. ID No. 6614 3124 Seq. ID No. 6615 1741584 1741551 1740970 Seq. ID No. 6616 3126 Seq. ID No. 6617 1742270 1742243 1741596 Seq. ID No. 6618 3129a Seq. ID No. 6619 1742959 1742902 1742246 Seq. ID No. 6620 3129b Seq. ID No. 6621 1742959 1742932 1742246 Seq. ID No. 6622 3131 Seq. ID No. 6623 1745173 1745167 1743977 Seq. ID No. 6624 3134a Seq. ID No. 6625 1747570 1747468 1745222 Seq. ID No. 6626 3134b Seq. ID No. 6627 1747570 1747507 1745222 Seq. ID No. 6628 3138 Seq. ID No. 6629 1748892 1748832 1747537 Seq. ID No. 6630 3140 Seq. ID No. 6631 1748324 1748327 1748560 Seq. ID No. 6632 3141 Seq. ID No. 6633 1750186 1750177 1748972 Seq. ID No. 6634 3145a Seq. ID No. 6635 1752277 1752205 1750973 Seq. ID No. 6636 3145b Seq. ID No. 6637 1752277 1752259 1750973 Seq. ID No. 6638 3145c Seq. ID No. 6639 1752277 1752274 1750973 Seq. ID No. 6640 3147a Seq. ID No. 6641 125 1754054 1752510 Seq. ID No. 6642 3147b Seq. ID No. 6643 125 122 1752510 Seq. ID No. 6644 3147c Seq. ID No. 6645 125 83 1752510 Seq. ID No. 6646 3149a Seq. ID No. 6647 7 1754326 1754123 Seq. ID No. 6648 3150a Seq. ID No. 6649 1753936 1754086 1754331 Seq. ID No. 6650

Listed in Table 3 are ORFs that have been identified using Signal P algorithm (i.e. Signal P value of “YES”) were considered to be surface exposed. 250 ORFs met all four of the criteria of the SignalP program for having a signal peptide (listed as a ‘YES’ in the SignalP column). A subset of 208 of these ORFs was also predicted by the HMM SignalP software to contain a signal peptide (Signal peptide). Of these 208 ORFs, the PSORT program predicted 21 ORFs to be localized to the periplasm (Peri); 29 ORFs to be localized to the outer membrane (OM); 153 ORFs to be localized to the cytoplasmic inner membrane (IM); and 5 ORFs to be localized to the cytoplasm. Of the 42 ORFs predicted by HMM SignalP to be non-secretory proteins (Non-secretory protein), 6 ORFs were predicted by PSORT to be localized to the periplasm and 7 ORFs were predicted by PSORT to be localized to the cytoplasm, 180 ORFs were predicted to be localized to the IM and 31 ORFs were predicted to be localized to the OM. TABLE 3 SIGNALP: YES DNA SEQ ID Protein SEQ ID ORF Number Number Number HMMSignalP PSORT 51c Seq. ID No. 89 Seq. ID No. 90 Non-secretory protein IM 69 Seq. ID No. 127 Seq. ID No. 128 Non-secretory protein Cyto 73a Seq. ID No. 131 Seq. ID No. 132 Signal peptide Cyto 73b Seq. ID No. 133 Seq. ID No. 134 Signal peptide Cyto 87a Seq. ID No. 161 Seq. ID No. 162 Signal peptide OM 87b Seq. ID No. 163 Seq. ID No. 164 Signal peptide IM 109c Seq. ID No. 213 Seq. ID No. 214 Signal peptide IM 109d Seq. ID No. 215 Seq. ID No. 216 Signal peptide IM 114 Seq. ID No. 225 Seq. ID No. 226 Signal peptide OM 129a Seq. ID No. 249 Seq. ID No. 250 Signal peptide IM 129b Seq. ID No. 251 Seq. ID No. 252 Signal peptide IM 145b Seq. ID No. 287 Seq. ID No. 288 Signal peptide IM 145c Seq. ID No. 289 Seq. ID No. 290 Signal peptide IM 179a Seq. ID No. 369 Seq. ID No. 370 Non-secretory protein IM 179b Seq. ID No. 371 Seq. ID No. 372 Non-secretory protein IM 180b Seq. ID No. 375 Seq. ID No. 376 Signal peptide IM 183a Seq. ID No. 377 Seq. ID No. 378 Non-secretory protein IM 245a Seq. ID No. 497 Seq. ID No. 498 Signal peptide IM 246a Seq. ID No. 503 Seq. ID No. 504 Signal peptide IM 246b Seq. ID No. 505 Seq. ID No. 506 Signal peptide IM 255b Seq. ID No. 527 Seq. ID No. 528 Signal peptide IM 264b Seq. ID No. 549 Seq. ID No. 550 Signal peptide IM 277c Seq. ID No. 575 Seq. ID No. 576 Signal peptide OM 297 Seq. ID No. 617 Seq. ID No. 618 Signal peptide Peri 318a Seq. ID No. 657 Seq. ID No. 658 Signal peptide OM 318b Seq. ID No. 659 Seq. ID No. 660 Signal peptide OM 318c Seq. ID No. 661 Seq. ID No. 662 Signal peptide IM 324 Seq. ID No. 675 Seq. ID No. 676 Signal peptide OM 342a Seq. ID No. 715 Seq. ID No. 716 Signal peptide IM 342b Seq. ID No. 717 Seq. ID No. 718 Signal peptide IM 349b Seq. ID No. 745 Seq. ID No. 746 Signal peptide OM 349c Seq. ID No. 747 Seq. ID No. 748 Signal peptide OM 352a Seq. ID No. 755 Seq. ID No. 756 Signal peptide IM 352b Seq. ID No. 757 Seq. ID No. 758 Signal peptide IM 352c Seq. ID No. 759 Seq. ID No. 760 Signal peptide IM 354a Seq. ID No. 761 Seq. ID No. 762 Signal peptide IM 356c Seq. ID No. 773 Seq. ID No. 774 Non-secretory protein IM 372d Seq. ID No. 807 Seq. ID No. 808 Signal peptide OM 448 Seq. ID No. 967 Seq. ID No. 968 Signal peptide IM 451a Seq. ID No. 973 Seq. ID No. 974 Non-secretory protein Peri 451b Seq. ID No. 975 Seq. ID No. 976 Non-secretory protein Peri 464b Seq. ID No. 1013 Seq. ID No. 1014 Signal peptide IM 471a Seq. ID No. 1025 Seq. ID No. 1026 Non-secretory protein Cyto 471b Seq. ID No. 1027 Seq. ID No. 1028 Non-secretory protein Cyto 472f Seq. ID No. 1039 Seq. ID No. 1040 Signal peptide IM 492 Seq. ID No. 1075 Seq. ID No. 1076 Signal peptide OM 499a Seq. ID No. 1089 Seq. ID No. 1090 Non-secretory protein IM 547a Seq. ID No. 1195 Seq. ID No. 1196 Signal peptide OM 547b Seq. ID No. 1197 Seq. ID No. 1198 Signal peptide IM 553c Seq. ID No. 1207 Seq. ID No. 1208 Non-secretory protein IM 571 Seq. ID No. 1239 Seq. ID No. 1240 Non-secretory protein Peri 576a Seq. ID No. 1243 Seq. ID No. 1244 Signal peptide Peri 576b Seq. ID No. 1245 Seq. ID No. 1246 Signal peptide IM 587c Seq. ID No. 1269 Seq. ID No. 1270 Signal peptide IM 609a Seq. ID No. 1315 Seq. ID No. 1316 Signal peptide IM 609b Seq. ID No. 1317 Seq. ID No. 1318 Signal peptide IM 613d Seq. ID No. 1331 Seq. ID No. 1332 Signal peptide IM 631b Seq. ID No. 1365 Seq. ID No. 1366 Signal peptide IM 631c Seq. ID No. 1367 Seq. ID No. 1368 Signal peptide IM 631d Seq. ID No. 1369 Seq. ID No. 1370 Signal peptide IM 679a Seq. ID No. 1445 Seq. ID No. 1446 Signal peptide Cyto 679b Seq. ID No. 1447 Seq. ID No. 1448 Signal peptide IM 722a Seq. ID No. 1513 Seq. ID No. 1514 Signal peptide IM 722c Seq. ID No. 1517 Seq. ID No. 1518 Signal peptide IM 738a Seq. ID No. 1545 Seq. ID No. 1546 Signal peptide IM 738c Seq. ID No. 1549 Seq. ID No. 1550 Non-secretory protein IM 743b Seq. ID No. 1561 Seq. ID No. 1562 Signal peptide IM 746a Seq. ID No. 1569 Seq. ID No. 1570 Non-secretory protein IM 746b Seq. ID No. 1571 Seq. ID No. 1572 Signal peptide IM 754b Seq. ID No. 1585 Seq. ID No. 1586 Signal peptide IM 786b Seq. ID No. 1643 Seq. ID No. 1644 Signal peptide Peri 789c Seq. ID No. 1653 Seq. ID No. 1654 Signal peptide IM 794b Seq. ID No. 1661 Seq. ID No. 1662 Signal peptide OM 794c Seq. ID No. 1663 Seq. ID No. 1664 Signal peptide OM 826 Seq. ID No. 1707 Seq. ID No. 1708 Signal peptide IM 837b Seq. ID No. 1733 Seq. ID No. 1734 Signal peptide IM 843 Seq. ID No. 1737 Seq. ID No. 1738 Signal peptide IM 853b Seq. ID No. 1755 Seq. ID No. 1756 Signal peptide IM 859a Seq. ID No. 1765 Seq. ID No. 1766 Signal peptide IM 859b Seq. ID No. 1767 Seq. ID No. 1768 Signal peptide IM 862 Seq. ID No. 1775 Seq. ID No. 1776 Non-secretory protein Peri 870 Seq. ID No. 1791 Seq. ID No. 1792 Signal peptide OM 876 Seq. ID No. 1805 Seq. ID No. 1806 Signal peptide Peri 931 Seq. ID No. 1875 Seq. ID No. 1876 Signal peptide IM 977a Seq. ID No. 1969 Seq. ID No. 1970 Signal peptide OM 981a Seq. ID No. 1981 Seq. ID No. 1982 Signal peptide IM 1017c Seq. ID No. 2053 Seq. ID No. 2054 Signal peptide IM 1017d Seq. ID No. 2055 Seq. ID No. 2056 Signal peptide IM 1036a Seq. ID No. 2087 Seq. ID No. 2088 Signal peptide IM 1036b Seq. ID No. 2089 Seq. ID No. 2090 Signal peptide IM 1036c Seq. ID No. 2091 Seq. ID No. 2092 Signal peptide IM 1044a Seq. ID No. 2105 Seq. ID No. 2106 Signal peptide IM 1047b Seq. ID No. 2115 Seq. ID No. 2116 Signal peptide OM 1065a Seq. ID No. 2149 Seq. ID No. 2150 Signal peptide Peri 1065b Seq. ID No. 2151 Seq. ID No. 2152 Signal peptide Peri 1067 Seq. ID No. 2159 Seq. ID No. 2160 Signal peptide OM 1077d Seq. ID No. 2177 Seq. ID No. 2178 Signal peptide IM 1141a Seq. ID No. 2277 Seq. ID No. 2278 Non-secretory protein Cyto 1146c Seq. ID No. 2293 Seq. ID No. 2294 Signal peptide IM 1155c Seq. ID No. 2321 Seq. ID No. 2322 Signal peptide IM 1167a Seq. ID No. 2347 Seq. ID No. 2348 Signal peptide Peri 1168 Seq. ID No. 2351 Seq. ID No. 2352 Signal peptide Peri 1169a Seq. ID No. 2353 Seq. ID No. 2354 Signal peptide IM 1172 Seq. ID No. 2365 Seq. ID No. 2366 Signal peptide IM 1182b Seq. ID No. 2395 Seq. ID No. 2396 Non-secretory protein IM 1192b Seq. ID No. 2421 Seq. ID No. 2422 Signal peptide IM 1196a Seq. ID No. 2425 Seq. ID No. 2426 Signal peptide Peri 1196b Seq. ID No. 2427 Seq. ID No. 2428 Signal peptide Peri 1197 Seq. ID No. 2429 Seq. ID No. 2430 Signal peptide IM 1207 Seq. ID No. 2449 Seq. ID No. 2450 Signal peptide OM 1212 Seq. ID No. 2459 Seq. ID No. 2460 Signal peptide IM 1237 Seq. ID No. 2525 Seq. ID No. 2526 Signal peptide OM 1241a Seq. ID No. 2531 Seq. ID No. 2532 Signal peptide IM 1268b Seq. ID No. 2607 Seq. ID No. 2608 Signal peptide IM 1288 Seq. ID No. 2651 Seq. ID No. 2652 Signal peptide IM 1308a Seq. ID No. 2679 Seq. ID No. 2680 Signal peptide IM 1315 Seq. ID No. 2693 Seq. ID No. 2694 Signal peptide IM 1318 Seq. ID No. 2699 Seq. ID No. 2700 Signal peptide IM 1319b Seq. ID No. 2703 Seq. ID No. 2704 Signal peptide IM 1348 Seq. ID No. 2753 Seq. ID No. 2754 Non-secretory protein IM 1366a Seq. ID No. 2785 Seq. ID No. 2786 Signal peptide Peri 1381b Seq. ID No. 2813 Seq. ID No. 2814 Signal peptide IM 1387a Seq. ID No. 2829 Seq. ID No. 2830 Non-secretory protein OM 1393a Seq. ID No. 2835 Seq. ID No. 2836 Signal peptide Peri 1393d Seq. ID No. 2841 Seq. ID No. 2842 Signal peptide IM 1412a Seq. ID No. 2879 Seq. ID No. 2880 Non-secretory protein IM 1412b Seq. ID No. 2881 Seq. ID No. 2882 Signal peptide IM 1438 Seq. ID No. 2935 Seq. ID No. 2936 Signal peptide OM 1439a Seq. ID No. 2937 Seq. ID No. 2938 Signal peptide IM 1440b Seq. ID No. 2949 Seq. ID No. 2950 Signal peptide IM 1446a Seq. ID No. 2965 Seq. ID No. 2966 Non-secretory protein IM 1446b Seq. ID No. 2967 Seq. ID No. 2968 Non-secretory protein IM 1448 Seq. ID No. 2973 Seq. ID No. 2974 Signal peptide IM 1463a Seq. ID No. 3007 Seq. ID No. 3008 Signal peptide IM 1463b Seq. ID No. 3009 Seq. ID No. 3010 Signal peptide IM 1463c Seq. ID No. 3011 Seq. ID No. 3012 Signal peptide IM 1470a Seq. ID No. 3029 Seq. ID No. 3030 Signal peptide IM 1470b Seq. ID No. 3031 Seq. ID No. 3032 Signal peptide IM 1503a Seq. ID No. 3109 Seq. ID No. 3110 Non-secretory protein IM 1503b Seq. ID No. 3111 Seq. ID No. 3112 Non-secretory protein IM 1559a Seq. ID No. 3219 Seq. ID No. 3220 Signal peptide IM 1563 Seq. ID No. 3223 Seq. ID No. 3224 Non-secretory protein Cyto 1584 Seq. ID No. 3273 Seq. ID No. 3274 Non-secretory protein Peri 1594a Seq. ID No. 3297 Seq. ID No. 3298 Signal peptide IM 1612 Seq. ID No. 3331 Seq. ID No. 3332 Signal peptide IM 1616b Seq. ID No. 3335 Seq. ID No. 3336 Signal peptide IM 1622a Seq. ID No. 3341 Seq. ID No. 3342 Non-secretory protein Cyto 1624 Seq. ID No. 3349 Seq. ID No. 3350 Signal peptide Peri 1625b Seq. ID No. 3353 Seq. ID No. 3354 Signal peptide IM 1625c Seq. ID No. 3355 Seq. ID No. 3356 Signal peptide IM 1634c Seq. ID No. 3377 Seq. ID No. 3378 Signal peptide IM 1646b Seq. ID No. 3391 Seq. ID No. 3392 Signal peptide IM 1659c Seq. ID No. 3425 Seq. ID No. 3426 Signal peptide IM 1673a Seq. ID No. 3449 Seq. ID No. 3450 Signal peptide IM 1688b Seq. ID No. 3493 Seq. ID No. 3494 Signal peptide IM 1718b Seq. ID No. 3573 Seq. ID No. 3574 Signal peptide Cyto 1743 Seq. ID No. 3611 Seq. ID No. 3612 Signal peptide IM 1747 Seq. ID No. 3619 Seq. ID No. 3620 Signal peptide IM 1784b Seq. ID No. 3689 Seq. ID No. 3690 Signal peptide IM 1808a Seq. ID No. 3753 Seq. ID No. 3754 Signal peptide IM 1808b Seq. ID No. 3755 Seq. ID No. 3756 Signal peptide IM 1809c Seq. ID No. 3765 Seq. ID No. 3766 Signal peptide IM 1812a Seq. ID No. 3781 Seq. ID No. 3782 Signal peptide IM 1812b Seq. ID No. 3783 Seq. ID No. 3784 Signal peptide IM 1842b Seq. ID No. 3851 Seq. ID No. 3852 Signal peptide IM 1862a Seq. ID No. 3903 Seq. ID No. 3904 Signal peptide IM 1919a Seq. ID No. 4005 Seq. ID No. 4006 Signal peptide Peri 1919b Seq. ID No. 4007 Seq. ID No. 4008 Signal peptide IM 1931b Seq. ID No. 4027 Seq. ID No. 4028 Signal peptide IM 1946b Seq. ID No. 4073 Seq. ID No. 4074 Signal peptide IM 1973 Seq. ID No. 4137 Seq. ID No. 4138 Signal peptide OM 1977a Seq. ID No. 4141 Seq. ID No. 4142 Signal peptide OM 1977b Seq. ID No. 4143 Seq. ID No. 4144 Signal peptide OM 1977c Seq. ID No. 4145 Seq. ID No. 4146 Signal peptide OM 2016c Seq. ID No. 4225 Seq. ID No. 4226 Signal peptide IM 2074b Seq. ID No. 4343 Seq. ID No. 4344 Signal peptide OM 2096a Seq. ID No. 4385 Seq. ID No. 4386 Signal peptide IM 2101 Seq. ID No. 4399 Seq. ID No. 4400 Signal peptide Peri 2140a Seq. ID No. 4469 Seq. ID No. 4470 Signal peptide IM 2147a Seq. ID No. 4483 Seq. ID No. 4484 Signal peptide IM 2150a Seq. ID No. 4493 Seq. ID No. 4494 Signal peptide IM 2150b Seq. ID No. 4495 Seq. ID No. 4496 Signal peptide IM 2165 Seq. ID No. 4533 Seq. ID No. 4534 Signal peptide IM 2245 Seq. ID No. 4699 Seq. ID No. 4700 Non-secretory protein OM 2253b Seq. ID No. 4709 Seq. ID No. 4710 Signal peptide IM 2253c Seq. ID No. 4711 Seq. ID No. 4712 Signal peptide IM 2264a Seq. ID No. 4735 Seq. ID No. 4736 Non-secretory protein Peri 2308 Seq. ID No. 4827 Seq. ID No. 4828 Signal peptide OM 2329b Seq. ID No. 4871 Seq. ID No. 4872 Signal peptide IM 2329c Seq. ID No. 4873 Seq. ID No. 4874 Signal peptide IM 2331 Seq. ID No. 4879 Seq. ID No. 4880 Non-secretory protein IM 2358 Seq. ID No. 4921 Seq. ID No. 4922 Signal peptide IM 2386b Seq. ID No. 4981 Seq. ID No. 4982 Non-secretory protein IM 2453 Seq. ID No. 5115 Seq. ID No. 5116 Signal peptide OM 2518a Seq. ID No. 5267 Seq. ID No. 5268 Signal peptide Cyto 2550c Seq. ID No. 5341 Seq. ID No. 5342 Signal peptide IM 2567b Seq. ID No. 5387 Seq. ID No. 5388 Signal peptide IM 2616d Seq. ID No. 5465 Seq. ID No. 5466 Signal peptide IM 2616e Seq. ID No. 5467 Seq. ID No. 5468 Non-secretory protein IM 2618a Seq. ID No. 5479 Seq. ID No. 5480 Non-secretory protein IM 2625a Seq. ID No. 5497 Seq. ID No. 5498 Signal peptide Peri 2629b Seq. ID No. 5513 Seq. ID No. 5514 Signal peptide OM 2648a Seq. ID No. 5543 Seq. ID No. 5544 Signal peptide IM 2648b Seq. ID No. 5545 Seq. ID No. 5546 Signal peptide IM 2659b Seq. ID No. 5567 Seq. ID No. 5568 Non-secretory protein IM 2669a Seq. ID No. 5587 Seq. ID No. 5588 Signal peptide Peri 2669b Seq. ID No. 5589 Seq. ID No. 5590 Signal peptide IM 2669c Seq. ID No. 5591 Seq. ID No. 5592 Signal peptide IM 2679b Seq. ID No. 5611 Seq. ID No. 5612 Signal peptide IM 2680c Seq. ID No. 5621 Seq. ID No. 5622 Signal peptide IM 2689b Seq. ID No. 5641 Seq. ID No. 5642 Signal peptide Peri 2718a Seq. ID No. 5681 Seq. ID No. 5682 Signal peptide IM 2734a Seq. ID No. 5719 Seq. ID No. 5720 Signal peptide IM 2749e Seq. ID No. 5771 Seq. ID No. 5772 Signal peptide IM 2757b Seq. ID No. 5783 Seq. ID No. 5784 Signal peptide IM 2801b Seq. ID No. 5895 Seq. ID No. 5896 Signal peptide IM 2805a Seq. ID No. 5899 Seq. ID No. 5900 Signal peptide IM 2805b Seq. ID No. 5901 Seq. ID No. 5902 Signal peptide IM 2818d Seq. ID No. 5927 Seq. ID No. 5928 Signal peptide IM 2818e Seq. ID No. 5929 Seq. ID No. 5930 Signal peptide IM 2822a Seq. ID No. 5939 Seq. ID No. 5940 Signal peptide IM 2852 Seq. ID No. 5987 Seq. ID No. 5988 Non-secretory protein IM 2862 Seq. ID No. 6013 Seq. ID No. 6014 Non-secretory protein Cyto 2900a Seq. ID No. 6087 Seq. ID No. 6088 Signal peptide Peri 2900b Seq. ID No. 6089 Seq. ID No. 6090 Signal peptide Peri 2901a Seq. ID No. 6091 Seq. ID No. 6092 Signal peptide IM 2901b Seq. ID No. 6093 Seq. ID No. 6094 Non-secretory protein IM 2902 Seq. ID No. 6095 Seq. ID No. 6096 Signal peptide IM 2906 Seq. ID No. 6103 Seq. ID No. 6104 Signal peptide IM 2933b Seq. ID No. 6169 Seq. ID No. 6170 Signal peptide IM 2941b Seq. ID No. 6185 Seq. ID No. 6186 Signal peptide IM 2941c Seq. ID No. 6187 Seq. ID No. 6188 Signal peptide IM 2943d Seq. ID No. 6195 Seq. ID No. 6196 Non-secretory protein IM 2944b Seq. ID No. 6197 Seq. ID No. 6198 Signal peptide IM 2948a Seq. ID No. 6203 Seq. ID No. 6204 Signal peptide IM 2948b Seq. ID No. 6205 Seq. ID No. 6206 Signal peptide IM 2955a Seq. ID No. 6221 Seq. ID No. 6222 Signal peptide IM 2955b Seq. ID No. 6223 Seq. ID No. 6224 Signal peptide IM 2955e Seq. ID No. 6229 Seq. ID No. 6230 Signal peptide IM 2980b Seq. ID No. 6291 Seq. ID No. 6292 Non-secretory protein IM 3037a Seq. ID No. 6415 Seq. ID No. 6416 Signal peptide OM 3037b Seq. ID No. 6417 Seq. ID No. 6418 Non-secretory protein IM 3064b Seq. ID No. 6473 Seq. ID No. 6474 Signal peptide Peri 3079 Seq. ID No. 6507 Seq. ID No. 6508 Non-secretory protein IM 3096b Seq. ID No. 6543 Seq. ID No. 6544 Signal peptide IM 3119b Seq. ID No. 6595 Seq. ID No. 6596 Signal peptide IM 3119c Seq. ID No. 6597 Seq. ID No. 6598 Signal peptide IM 3119d Seq. ID No. 6599 Seq. ID No. 6600 Signal peptide IM 3119e Seq. ID No. 6601 Seq. ID No. 6602 Signal peptide IM 3119f Seq. ID No. 6603 Seq. ID No. 6604 Signal peptide IM

Listed in Table 4 are all 526 ORFs of the SignalP program that met only three of the criteria of having a signal peptide (listed as a ‘yes’ in the SignalP column). A subset of 359 of these ORFs was also predicted by the HMM SignalP software to contain a signal peptide. Of these 359 ORFs, the PSORT program predicted 24 ORFs to be localized to the periplasm (Peri); 44 ORFs to be localized to the outer membrane (OM); 267 ORFs to be localized to the cytoplasmic membrane (IM); and 24 ORFs to be localized to the cytoplasm. Of the 167 ORFs predicted by HMM SignalP to be Non-secretory proteins, PSORT predicted 6 ORFs to be localized to the periplasm; 1 ORF to be localized to the outer membrane; 122 ORFs to be localized to the cytoplasmic membrane; and 38 ORFs to be localized to the cytoplasm. Also listed for all ORFs is the predicted number of transmembrane, a-helical hydrophobic domains predicted by the TopPred2 software (listed in the MSD column). If no value is listed, none has yet been determined. (The same is also the case for Tables 5 and 6). TABLE 4 SIGNALP: YES ORF DNA SEQ ID Protein SEQ ID Number Number Number HMMSignalP PSORT MSD 4a Seq. ID No. 7 Seq. ID No. 8 Signal peptide IM 4 4c Seq. ID No. 11 Seq. ID No. 12 Non-secretory protein IM 12 16 Seq. ID No. 23 Seq. ID No. 24 Non-secretory protein IM 0 38a Seq. ID No. 45 Seq. ID No. 46 Signal peptide OM 1 38b Seq. ID No. 47 Seq. ID No. 48 Signal peptide OM 1 40 Seq. ID No. 53 Seq. ID No. 54 Signal peptide IM 1 41c Seq. ID No. 59 Seq. ID No. 60 Non-secretory protein IM 1 44a Seq. ID No. 65 Seq. ID No. 66 Signal peptide IM 2 44b Seq. ID No. 67 Seq. ID No. 68 Signal peptide IM 2 51b Seq. ID No. 87 Seq. ID No. 88 Signal peptide IM 9 55 Seq. ID No. 91 Seq. ID No. 92 Non-secretory protein IM 1 79 Seq. ID No. 139 Seq. ID No. 140 Non-secretory protein IM 2 83 Seq. ID No. 151 Seq. ID No. 152 Non-secretory protein IM 2 86 Seq. ID No. 159 Seq. ID No. 160 Signal peptide Peri 1 87c Seq. ID No. 165 Seq. ID No. 166 Non-secretory protein IM 2 89 Seq. ID No. 169 Seq. ID No. 170 Non-secretory protein IM 2 94 Seq. ID No. 185 Seq. ID No. 186 Non-secretory protein IM 2 109b Seq. ID No. 211 Seq. ID No. 212 Signal peptide IM 7 111a Seq. ID No. 217 Seq. ID No. 218 Signal peptide IM 6 124a Seq. ID No. 235 Seq. ID No. 236 Signal peptide IM 1 124b Seq. ID No. 237 Seq. ID No. 238 Signal peptide IM 3 124c Seq. ID No. 239 Seq. ID No. 240 Non-secretory protein IM 5 138a Seq. ID No. 271 Seq. ID No. 272 Signal peptide IM 6 145a Seq. ID No. 285 Seq. ID No. 286 Signal peptide IM 3 145d Seq. ID No. 291 Seq. ID No. 292 Non-secretory protein IM 12 162a Seq. ID No. 327 Seq. ID No. 328 Signal peptide IM 2 170 Seq. ID No. 349 Seq. ID No. 350 Non-secretory protein IM 1 187a Seq. ID No. 385 Seq. ID No. 386 Non-secretory protein IM 1 187b Seq. ID No. 387 Seq. ID No. 388 Non-secretory protein IM 1 196 Seq. ID No. 407 Seq. ID No. 408 Non-secretory protein Cyto 1 205 Seq. ID No. 427 Seq. ID No. 428 Non-secretory protein Cyto 207 Seq. ID No. 431 Seq. ID No. 432 Non-secretory protein IM 0 223a Seq. ID No. 455 Seq. ID No. 456 Signal peptide Cyto 1 223b Seq. ID No. 457 Seq. ID No. 458 Signal peptide Cyto 1 241 Seq. ID No. 495 Seq. ID No. 496 Signal peptide IM 1 245b Seq. ID No. 499 Seq. ID No. 500 Signal peptide IM 10 248b Seq. ID No. 511 Seq. ID No. 512 Signal peptide IM 9 249a Seq. ID No. 513 Seq. ID No. 514 Signal peptide OM 1 249b Seq. ID No. 515 Seq. ID No. 516 Signal peptide IM 1 255a Seq. ID No. 525 Seq. ID No. 526 Signal peptide IM 6 263a Seq. ID No. 545 Seq. ID No. 546 Signal peptide OM 1 263b Seq. ID No. 547 Seq. ID No. 548 Signal peptide IM 1 268 Seq. ID No. 557 Seq. ID No. 558 Signal peptide Cyto 1 273b Seq. ID No. 569 Seq. ID No. 570 Signal peptide IM 12 282 Seq. ID No. 589 Seq. ID No. 590 Non-secretory protein Cyto 283a Seq. ID No. 591 Seq. ID No. 592 Signal peptide OM 1 283b Seq. ID No. 593 Seq. ID No. 594 Signal peptide OM 1 284a Seq. ID No. 595 Seq. ID No. 596 Non-secretory protein IM 5 290b Seq. ID No. 609 Seq. ID No. 610 Non-secretory protein IM 311 Seq. ID No. 637 Seq. ID No. 638 Signal peptide IM 6 313a Seq. ID No. 639 Seq. ID No. 640 Signal peptide IM 2 313b Seq. ID No. 641 Seq. ID No. 642 Signal peptide IM 3 317a Seq. ID No. 653 Seq. ID No. 654 Signal peptide IM 2 321 Seq. ID No. 669 Seq. ID No. 670 Signal peptide OM 1 327b Seq. ID No. 679 Seq. ID No. 680 Signal peptide IM 5 342c Seq. ID No. 719 Seq. ID No. 720 Signal peptide IM 4 342e Seq. ID No. 723 Seq. ID No. 724 Signal peptide IM 10 346b Seq. ID No. 739 Seq. ID No. 740 Non-secretory protein Cyto 0 350a Seq. ID No. 749 Seq. ID No. 750 Signal peptide IM 6 350b Seq. ID No. 751 Seq. ID No. 752 Signal peptide IM 6 354b Seq. ID No. 763 Seq. ID No. 764 Signal peptide IM 6 354c Seq. ID No. 765 Seq. ID No. 766 Signal peptide IM 6 356a Seq. ID No. 769 Seq. ID No. 770 Signal peptide IM 3 358a Seq. ID No. 777 Seq. ID No. 778 Signal peptide IM 3 358b Seq. ID No. 779 Seq. ID No. 780 Signal peptide IM 10 358c Seq. ID No. 781 Seq. ID No. 782 Signal peptide IM 10 382b Seq. ID No. 819 Seq. ID No. 820 Signal peptide OM 1 418b Seq. ID No. 895 Seq. ID No. 896 Non-secretory protein IM 7 420a Seq. ID No. 903 Seq. ID No. 904 Non-secretory protein IM 1 420b Seq. ID No. 905 Seq. ID No. 906 Non-secretory protein IM 1 422 Seq. ID No. 909 Seq. ID No. 910 Non-secretory protein Cyto 431 Seq. ID No. 935 Seq. ID No. 936 Signal peptide OM 1 434 Seq. ID No. 937 Seq. ID No. 938 Signal peptide IM 2 440 Seq. ID No. 951 Seq. ID No. 952 Non-secretory protein IM 2 441b Seq. ID No. 955 Seq. ID No. 956 Signal peptide IM 2 452b Seq. ID No. 979 Seq. ID No. 980 Signal peptide IM 4 452c Seq. ID No. 981 Seq. ID No. 982 Signal peptide IM 4 452d Seq. ID No. 983 Seq. ID No. 984 Signal peptide IM 4 452e Seq. ID No. 985 Seq. ID No. 986 Signal peptide IM 4 462 Seq. ID No. 1005 Seq. ID No. 1006 Signal peptide Peri 1 463a Seq. ID No. 1007 Seq. ID No. 1008 Signal peptide Peri 1 463b Seq. ID No. 1009 Seq. ID No. 1010 Signal peptide Peri 1 464c Seq. ID No. 1015 Seq. ID No. 1016 Signal peptide IM 11 465b Seq. ID No. 1019 Seq. ID No. 1020 Signal peptide OM 3 472a Seq. ID No. 1029 Seq. ID No. 1030 Signal peptide IM 4 472b Seq. ID No. 1031 Seq. ID No. 1032 Signal peptide IM 5 477b Seq. ID No. 1047 Seq. ID No. 1048 Non-secretory protein Cyto 0 499b Seq. ID No. 1091 Seq. ID No. 1092 Non-secretory protein IM 2 510 Seq. ID No. 1111 Seq. ID No. 1112 Non-secretory protein Cyto 524b Seq. ID No. 1137 Seq. ID No. 1138 Signal peptide IM 6 530a Seq. ID No. 1151 Seq. ID No. 1152 Signal peptide IM 530b Seq. ID No. 1153 Seq. ID No. 1154 Non-secretory protein Peri 541c Seq. ID No. 1169 Seq. ID No. 1170 Signal peptide IM 5 542 Seq. ID No. 1173 Seq. ID No. 1174 Signal peptide IM 1 545a Seq. ID No. 1183 Seq. ID No. 1184 Signal peptide IM 3 546b Seq. ID No. 1191 Seq. ID No. 1192 Non-secretory protein IM 1 546c Seq. ID No. 1193 Seq. ID No. 1194 Non-secretory protein IM 1 556 Seq. ID No. 1213 Seq. ID No. 1214 Signal peptide IM 2 561 Seq. ID No. 1223 Seq. ID No. 1224 Signal peptide IM 5 564b Seq. ID No. 1229 Seq. ID No. 1230 Signal peptide IM 4 578a Seq. ID No. 1247 Seq. ID No. 1248 Non-secretory protein Cyto 0 585b Seq. ID No. 1259 Seq. ID No. 1260 Signal peptide Cyto 0 595a Seq. ID No. 1283 Seq. ID No. 1284 Signal peptide IM 2 603a Seq. ID No. 1307 Seq. ID No. 1308 Non-secretory protein Cyto 1 610a Seq. ID No. 1319 Seq. ID No. 1320 Signal peptide IM 1 610b Seq. ID No. 1321 Seq. ID No. 1322 Non-secretory protein IM 1 613b Seq. ID No. 1327 Seq. ID No. 1328 Signal peptide IM 7 619a Seq. ID No. 1341 Seq. ID No. 1342 Signal peptide Cyto 1 619b Seq. ID No. 1343 Seq. ID No. 1344 Signal peptide Cyto 1 623 Seq. ID No. 1347 Seq. ID No. 1348 Signal peptide Peri 1 640 Seq. ID No. 1389 Seq. ID No. 1390 Non-secretory protein Cyto 0 645 Seq. ID No. 1401 Seq. ID No. 1402 Signal peptide Peri 1 665 Seq. ID No. 1429 Seq. ID No. 1430 Signal peptide IM 3 699b Seq. ID No. 1479 Seq. ID No. 1480 Non-secretory protein IM 1 739 Seq. ID No. 1551 Seq. ID No. 1552 Signal peptide IM 2 743a Seq. ID No. 1559 Seq. ID No. 1560 Signal peptide IM 2 749 Seq. ID No. 1579 Seq. ID No. 1580 Signal peptide IM 1 754c Seq. ID No. 1587 Seq. ID No. 1588 Non-secretory protein IM 9 772a Seq. ID No. 1621 Seq. ID No. 1622 Signal peptide IM 5 775 Seq. ID No. 1627 Seq. ID No. 1628 Non-secretory protein IM 7 779 Seq. ID No. 1633 Seq. ID No. 1634 Signal peptide Peri 2 788a Seq. ID No. 1645 Seq. ID No. 1646 Signal peptide IM 4 788b Seq. ID No. 1647 Seq. ID No. 1648 Signal peptide IM 6 789a Seq. ID No. 1649 Seq. ID No. 1650 Signal peptide IM 4 791 Seq. ID No. 1655 Seq. ID No. 1656 Non-secretory protein Cyto 794d Seq. ID No. 1665 Seq. ID No. 1666 Signal peptide OM 0 795 Seq. ID No. 1667 Seq. ID No. 1668 Non-secretory protein Cyto 799a Seq. ID No. 1671 Seq. ID No. 1672 Signal peptide IM 2 799d Seq. ID No. 1677 Seq. ID No. 1678 Signal peptide IM 9 799e Seq. ID No. 1679 Seq. ID No. 1680 Signal peptide IM 10 799f Seq. ID No. 1681 Seq. ID No. 1682 Signal peptide IM 10 809b Seq. ID No. 1695 Seq. ID No. 1696 Non-secretory protein IM 4 820a Seq. ID No. 1703 Seq. ID No. 1704 Non-secretory protein IM 0 820b Seq. ID No. 1705 Seq. ID No. 1706 Non-secretory protein IM 0 837a Seq. ID No. 1731 Seq. ID No. 1732 Signal peptide IM 2 853a Seq. ID No. 1753 Seq. ID No. 1754 Signal peptide IM 3 854 Seq. ID No. 1759 Seq. ID No. 1760 Non-secretory protein IM 2 857 Seq. ID No. 1763 Seq. ID No. 1764 Non-secretory protein Peri 1 868a Seq. ID No. 1787 Seq. ID No. 1788 Signal peptide IM 3 873c Seq. ID No. 1797 Seq. ID No. 1798 Signal peptide OM 1 886 Seq. ID No. 1821 Seq. ID No. 1822 Signal peptide OM 1 887 Seq. ID No. 1823 Seq. ID No. 1824 Signal peptide IM 1 904 Seq. ID No. 1833 Seq. ID No. 1834 Non-secretory protein Peri 908a Seq. ID No. 1839 Seq. ID No. 1840 Signal peptide IM 6 908b Seq. ID No. 1841 Seq. ID No. 1842 Non-secretory protein IM 9 908c Seq. ID No. 1843 Seq. ID No. 1844 Non-secretory protein IM 9 939b Seq. ID No. 1893 Seq. ID No. 1894 Signal peptide IM 10 951a Seq. ID No. 1917 Seq. ID No. 1918 Signal peptide OM 0 951b Seq. ID No. 1919 Seq. ID No. 1920 Signal peptide IM 0 977b Seq. ID No. 1971 Seq. ID No. 1972 Non-secretory protein Cyto 1 987 Seq. ID No. 1991 Seq. ID No. 1992 Signal peptide IM 5 998a Seq. ID No. 2013 Seq. ID No. 2014 Signal peptide IM 5 998b Seq. ID No. 2015 Seq. ID No. 2016 Non-secretory protein IM 5 999a Seq. ID No. 2017 Seq. ID No. 2018 Signal peptide IM 2 999b Seq. ID No. 2019 Seq. ID No. 2020 Signal peptide IM 2 1006a Seq. ID No. 2033 Seq. ID No. 2034 Signal peptide Peri 1 1006b Seq. ID No. 2035 Seq. ID No. 2036 Signal peptide Cyto 1 1017a Seq. ID No. 2049 Seq. ID No. 2050 Signal peptide IM 4 1035a Seq. ID No. 2081 Seq. ID No. 2082 Non-secretory protein IM 1 1035b Seq. ID No. 2083 Seq. ID No. 2084 Non-secretory protein IM 1 1035c Seq. ID No. 2085 Seq. ID No. 2086 Non-secretory protein IM 1 1044d Seq. ID No. 2111 Seq. ID No. 2112 Non-secretory protein IM 3 1047a Seq. ID No. 2113 Seq. ID No. 2114 Signal peptide OM 1 1050b Seq. ID No. 2123 Seq. ID No. 2124 Signal peptide IM 7 1050c Seq. ID No. 2125 Seq. ID No. 2126 Signal peptide IM 7 1050d Seq. ID No. 2127 Seq. ID No. 2128 Signal peptide IM 7 1056a Seq. ID No. 2131 Seq. ID No. 2132 Non-secretory protein Cyto 1056b Seq. ID No. 2133 Seq. ID No. 2134 Non-secretory protein Cyto 1065c Seq. ID No. 2153 Seq. ID No. 2154 Non-secretory protein IM 1 1069 Seq. ID No. 2161 Seq. ID No. 2162 Non-secretory protein IM 1 1077a Seq. ID No. 2171 Seq. ID No. 2172 Signal peptide IM 3 1077c Seq. ID No. 2175 Seq. ID No. 2176 Non-secretory protein IM 12 1077e Seq. ID No. 2179 Seq. ID No. 2180 Non-secretory protein IM 15 1081a Seq. ID No. 2187 Seq. ID No. 2188 Signal peptide Peri 1 1091a Seq. ID No. 2201 Seq. ID No. 2202 Non-secretory protein Cyto 1091b Seq. ID No. 2203 Seq. ID No. 2204 Non-secretory protein Peri 1098b Seq. ID No. 2221 Seq. ID No. 2222 Non-secretory protein IM 2 1111a Seq. ID No. 2237 Seq. ID No. 2238 Signal peptide IM 6 1126b Seq. ID No. 2249 Seq. ID No. 2250 Signal peptide IM 4 1126c Seq. ID No. 2251 Seq. ID No. 2252 Signal peptide IM 4 1128 Seq. ID No. 2255 Seq. ID No. 2256 Signal peptide IM 2 1135a Seq. ID No. 2261 Seq. ID No. 2262 Non-secretory protein IM 1 1135b Seq. ID No. 2263 Seq. ID No. 2264 Non-secretory protein IM 1 1140a Seq. ID No. 2271 Seq. ID No. 2272 Signal peptide IM 2 1141b Seq. ID No. 2279 Seq. ID No. 2280 Non-secretory protein Cyto 1 1144a Seq. ID No. 2283 Seq. ID No. 2284 Signal peptide IM 2 1144b Seq. ID No. 2285 Seq. ID No. 2286 Non-secretory protein IM 4 1146a Seq. ID No. 2289 Seq. ID No. 2290 Signal peptide IM 3 1146d Seq. ID No. 2295 Seq. ID No. 2296 Signal peptide IM 8 1152b Seq. ID No. 2305 Seq. ID No. 2306 Signal peptide IM 5 1152c Seq. ID No. 2307 Seq. ID No. 2308 Signal peptide IM 6 1155a Seq. ID No. 2317 Seq. ID No. 2318 Signal peptide IM 3 1155b Seq. ID No. 2319 Seq. ID No. 2320 Signal peptide IM 4 1155d Seq. ID No. 2323 Seq. ID No. 2324 Signal peptide IM 6 1155e Seq. ID No. 2325 Seq. ID No. 2326 Signal peptide IM 9 1165 Seq. ID No. 2343 Seq. ID No. 2344 Signal peptide OM 1 1167b Seq. ID No. 2349 Seq. ID No. 2350 Signal peptide IM 2 1180b Seq. ID No. 2385 Seq. ID No. 2386 Non-secretory protein IM 2 1182a Seq. ID No. 2393 Seq. ID No. 2394 Signal peptide IM 1 1194 Seq. ID No. 2423 Seq. ID No. 2424 Non-secretory protein IM 1 1209 Seq. ID No. 2453 Seq. ID No. 2454 Non-secretory protein IM 4 1224c Seq. ID No. 2491 Seq. ID No. 2492 Signal peptide IM 6 1228a Seq. ID No. 2497 Seq. ID No. 2498 Signal peptide IM 1 1228b Seq. ID No. 2499 Seq. ID No. 2500 Signal peptide IM 2 1231 Seq. ID No. 2507 Seq. ID No. 2508 Signal peptide OM 1 1234a Seq. ID No. 2515 Seq. ID No. 2516 Signal peptide IM 4 1234b Seq. ID No. 2517 Seq. ID No. 2518 Signal peptide IM 4 1235 Seq. ID No. 2521 Seq. ID No. 2522 Non-secretory protein Cyto 1 1236a Seq. ID No. 2523 Seq. ID No. 2524 Signal peptide IM 2 1239 Seq. ID No. 2527 Seq. ID No. 2528 Signal peptide OM 1 1241b Seq. ID No. 2533 Seq. ID No. 2534 Signal peptide IM 7 1241c Seq. ID No. 2535 Seq. ID No. 2536 Signal peptide IM 7 1245a Seq. ID No. 2541 Seq. ID No. 2542 Signal peptide IM 6 1245b Seq. ID No. 2543 Seq. ID No. 2544 Signal peptide IM 10 1245d Seq. ID No. 2547 Seq. ID No. 2548 Non-secretory protein IM 12 1245e Seq. ID No. 2549 Seq. ID No. 2550 Non-secretory protein IM 12 1250b Seq. ID No. 2557 Seq. ID No. 2558 Signal peptide IM 8 1253c Seq. ID No. 2573 Seq. ID No. 2574 Non-secretory protein IM 7 1258a Seq. ID No. 2583 Seq. ID No. 2584 Signal peptide IM 5 1267a Seq. ID No. 2601 Seq. ID No. 2602 Signal peptide IM 2 1267b Seq. ID No. 2603 Seq. ID No. 2604 Non-secretory protein IM 3 1275a Seq. ID No. 2621 Seq. ID No. 2622 Signal peptide Cyto 1 1289 Seq. ID No. 2653 Seq. ID No. 2654 Non-secretory protein IM 1 1308b Seq. ID No. 2681 Seq. ID No. 2682 Signal peptide IM 4 1314b Seq. ID No. 2691 Seq. ID No. 2692 Signal peptide IM 1 1319a Seq. ID No. 2701 Seq. ID No. 2702 Signal peptide IM 4 1335a Seq. ID No. 2733 Seq. ID No. 2734 Signal peptide OM 2 1338 Seq. ID No. 2739 Seq. ID No. 2740 Non-secretory protein IM 1 1375 Seq. ID No. 2801 Seq. ID No. 2802 Signal peptide Cyto 0 1379 Seq. ID No. 2807 Seq. ID No. 2808 Non-secretory protein IM 1 1382 Seq. ID No. 2815 Seq. ID No. 2816 Signal peptide OM 1 1384a Seq. ID No. 2819 Seq. ID No. 2820 Signal peptide IM 2 1384b Seq. ID No. 2821 Seq. ID No. 2822 Signal peptide IM 2 1384c Seq. ID No. 2823 Seq. ID No. 2824 Signal peptide IM 2 1389a Seq. ID No. 2833 Seq. ID No. 2834 Signal peptide Cyto 0 1393b Seq. ID No. 2837 Seq. ID No. 2838 Signal peptide IM 2 1393c Seq. ID No. 2839 Seq. ID No. 2840 Signal peptide IM 3 1395a Seq. ID No. 2845 Seq. ID No. 2846 Signal peptide Cyto 1399a Seq. ID No. 2853 Seq. ID No. 2854 Signal peptide IM 2 1402c Seq. ID No. 2861 Seq. ID No. 2862 Signal peptide IM 2 1407b Seq. ID No. 2865 Seq. ID No. 2866 Non-secretory protein IM 1 1411a Seq. ID No. 2873 Seq. ID No. 2874 Signal peptide IM 3 1411b Seq. ID No. 2875 Seq. ID No. 2876 Non-secretory protein IM 4 1411c Seq. ID No. 2877 Seq. ID No. 2878 Non-secretory protein IM 6 1414a Seq. ID No. 2883 Seq. ID No. 2884 Non-secretory protein IM 0 1419 Seq. ID No. 2895 Seq. ID No. 2896 Non-secretory protein IM 1426a Seq. ID No. 2905 Seq. ID No. 2906 Signal peptide IM 4 1439b Seq. ID No. 2939 Seq. ID No. 2940 Signal peptide IM 5 1439c Seq. ID No. 2941 Seq. ID No. 2942 Signal peptide IM 6 1440a Seq. ID No. 2947 Seq. ID No. 2948 Signal peptide IM 6 1452a Seq. ID No. 2981 Seq. ID No. 2982 Signal peptide IM 4 1452b Seq. ID No. 2983 Seq. ID No. 2984 Signal peptide IM 4 1454 Seq. ID No. 2987 Seq. ID No. 2988 Signal peptide Cyto 1 1455b Seq. ID No. 2991 Seq. ID No. 2992 Signal peptide OM 1 1457a Seq. ID No. 2995 Seq. ID No. 2996 Signal peptide IM 3 1459 Seq. ID No. 3001 Seq. ID No. 3002 Non-secretory protein IM 1 1462b Seq. ID No. 3005 Seq. ID No. 3006 Signal peptide IM 6 1467 Seq. ID No. 3021 Seq. ID No. 3022 Non-secretory protein Cyto 2 1469b Seq. ID No. 3025 Seq. ID No. 3026 Signal peptide IM 5 1475 Seq. ID No. 3043 Seq. ID No. 3044 Signal peptide OM 1 1476 Seq. ID No. 3045 Seq. ID No. 3046 Non-secretory protein IM 5 1488a Seq. ID No. 3073 Seq. ID No. 3074 Signal peptide IM 1 1488b Seq. ID No. 3075 Seq. ID No. 3076 Signal peptide IM 2 1520 Seq. ID No. 3155 Seq. ID No. 3156 Signal peptide Peri 1 1530a Seq. ID No. 3163 Seq. ID No. 3164 Signal peptide OM 1 1530b Seq. ID No. 3165 Seq. ID No. 3166 Signal peptide IM 1 1533a Seq. ID No. 3167 Seq. ID No. 3168 Non-secretory protein IM 0 1543 Seq. ID No. 3183 Seq. ID No. 3184 Signal peptide OM 1 1557a Seq. ID No. 3213 Seq. ID No. 3214 Signal peptide IM 4 1557b Seq. ID No. 3215 Seq. ID No. 3216 Signal peptide IM 5 1569 Seq. ID No. 3235 Seq. ID No. 3236 Non-secretory protein IM 2 1572c Seq. ID No. 3245 Seq. ID No. 3246 Signal peptide IM 10 1580a Seq. ID No. 3261 Seq. ID No. 3262 Signal peptide IM 1 1580b Seq. ID No. 3263 Seq. ID No. 3264 Signal peptide IM 1 1581 Seq. ID No. 3265 Seq. ID No. 3266 Non-secretory protein IM 1 1582b Seq. ID No. 3269 Seq. ID No. 3270 Signal peptide IM 1 1582c Seq. ID No. 3271 Seq. ID No. 3272 Non-secretory protein IM 1 1585a Seq. ID No. 3275 Seq. ID No. 3276 Signal peptide IM 1 1585b Seq. ID No. 3277 Seq. ID No. 3278 Signal peptide IM 1 1606a Seq. ID No. 3317 Seq. ID No. 3318 Signal peptide IM 1 1608 Seq. ID No. 3325 Seq. ID No. 3326 Signal peptide Cyto 1 1619 Seq. ID No. 3337 Seq. ID No. 3338 Signal peptide OM 1 1625a Seq. ID No. 3351 Seq. ID No. 3352 Signal peptide IM 4 1646a Seq. ID No. 3389 Seq. ID No. 3390 Signal peptide IM 2 1649a Seq. ID No. 3405 Seq. ID No. 3406 Signal peptide Peri 2 1657 Seq. ID No. 3419 Seq. ID No. 3420 Non-secretory protein Cyto 1659a Seq. ID No. 3421 Seq. ID No. 3422 Signal peptide OM 1 1659b Seq. ID No. 3423 Seq. ID No. 3424 Non-secretory protein IM 9 1673b Seq. ID No. 3451 Seq. ID No. 3452 Signal peptide IM 8 1673c Seq. ID No. 3453 Seq. ID No. 3454 Signal peptide IM 10 1673d Seq. ID No. 3455 Seq. ID No. 3456 Signal peptide IM 12 1688a Seq. ID No. 3491 Seq. ID No. 3492 Signal peptide IM 3 1688c Seq. ID No. 3495 Seq. ID No. 3496 Non-secretory protein IM 11 1690a Seq. ID No. 3503 Seq. ID No. 3504 Signal peptide IM 1 1690b Seq. ID No. 3505 Seq. ID No. 3506 Signal peptide IM 2 1694c Seq. ID No. 3517 Seq. ID No. 3518 Signal peptide IM 1 1694d Seq. ID No. 3519 Seq. ID No. 3520 Signal peptide IM 1 1705a Seq. ID No. 3545 Seq. ID No. 3546 Non-secretory protein Cyto 1705b Seq. ID No. 3547 Seq. ID No. 3548 Non-secretory protein Cyto 1718a Seq. ID No. 3571 Seq. ID No. 3572 Non-secretory protein Cyto 1735a Seq. ID No. 3593 Seq. ID No. 3594 Signal peptide OM 1 1745 Seq. ID No. 3617 Seq. ID No. 3618 Signal peptide Peri 0 1749a Seq. ID No. 3621 Seq. ID No. 3622 Signal peptide IM 3 1752b Seq. ID No. 3629 Seq. ID No. 3630 Signal peptide Peri 1 1769b Seq. ID No. 3663 Seq. ID No. 3664 Non-secretory protein IM 7 1790a Seq. ID No. 3701 Seq. ID No. 3702 Non-secretory protein Cyto 2 1790b Seq. ID No. 3703 Seq. ID No. 3704 Non-secretory protein Cyto 3 1798a Seq. ID No. 3723 Seq. ID No. 3724 Signal peptide IM 2 1804a Seq. ID No. 3737 Seq. ID No. 3738 Non-secretory protein IM 2 1805 Seq. ID No. 3741 Seq. ID No. 3742 Signal peptide IM 3 1806b Seq. ID No. 3745 Seq. ID No. 3746 Signal peptide IM 5 1806c Seq. ID No. 3747 Seq. ID No. 3748 Non-secretory protein IM 5 1808d Seq. ID No. 3759 Seq. ID No. 3760 Non-secretory protein IM 15 1809b Seq. ID No. 3763 Seq. ID No. 3764 Signal peptide IM 7 1809d Seq. ID No. 3767 Seq. ID No. 3768 Non-secretory protein IM 12 1809e Seq. ID No. 3769 Seq. ID No. 3770 Non-secretory protein IM 14 1809f Seq. ID No. 3771 Seq. ID No. 3772 Non-secretory protein IM 14 1813 Seq. ID No. 3785 Seq. ID No. 3786 Non-secretory protein IM 1 1816a Seq. ID No. 3793 Seq. ID No. 3794 Signal peptide Peri 1 1825 Seq. ID No. 3813 Seq. ID No. 3814 Signal peptide IM 2 1838a Seq. ID No. 3837 Seq. ID No. 3838 Signal peptide IM 3 1838b Seq. ID No. 3839 Seq. ID No. 3840 Signal peptide IM 4 1845b Seq. ID No. 3861 Seq. ID No. 3862 Signal peptide IM 8 1848a Seq. ID No. 3865 Seq. ID No. 3866 Signal peptide IM 7 1857b Seq. ID No. 3889 Seq. ID No. 3890 Signal peptide IM 5 1857c Seq. ID No. 3891 Seq. ID No. 3892 Signal peptide IM 6 1858 Seq. ID No. 3895 Seq. ID No. 3896 Signal peptide Cyto 0 1868 Seq. ID No. 3915 Seq. ID No. 3916 Signal peptide IM 1 1873b Seq. ID No. 3923 Seq. ID No. 3924 Signal peptide Peri 1 1873c Seq. ID No. 3925 Seq. ID No. 3926 Signal peptide Peri 1 1875c Seq. ID No. 3929 Seq. ID No. 3930 Non-secretory protein IM 1 1896b Seq. ID No. 3965 Seq. ID No. 3966 Non-secretory protein IM 2 1898b Seq. ID No. 3975 Seq. ID No. 3976 Signal peptide IM 4 1900 Seq. ID No. 3979 Seq. ID No. 3980 Non-secretory protein Cyto 1 1917a Seq. ID No. 3995 Seq. ID No. 3996 Signal peptide IM 0 1917b Seq. ID No. 3997 Seq. ID No. 3998 Signal peptide IM 0 1919c Seq. ID No. 4009 Seq. ID No. 4010 Signal peptide IM 1 1936 Seq. ID No. 4039 Seq. ID No. 4040 Signal peptide IM 6 1937a Seq. ID No. 4041 Seq. ID No. 4042 Signal peptide IM 2 1941b Seq. ID No. 4061 Seq. ID No. 4062 Signal peptide IM 4 1950 Seq. ID No. 4079 Seq. ID No. 4080 Signal peptide OM 1 1951a Seq. ID No. 4081 Seq. ID No. 4082 Signal peptide IM 3 1960c Seq. ID No. 4111 Seq. ID No. 4112 Signal peptide IM 1 1961 Seq. ID No. 4113 Seq. ID No. 4114 Non-secretory protein IM 1 1972 Seq. ID No. 4135 Seq. ID No. 4136 Signal peptide Cyto 1 1976 Seq. ID No. 4139 Seq. ID No. 4140 Signal peptide IM 1 1981 Seq. ID No. 4155 Seq. ID No. 4156 Non-secretory protein Cyto 1 1991 Seq. ID No. 4181 Seq. ID No. 4182 Signal peptide Cyto 1 2008 Seq. ID No. 4203 Seq. ID No. 4204 Non-secretory protein IM 2 2016a Seq. ID No. 4221 Seq. ID No. 4222 Signal peptide IM 2 2024b Seq. ID No. 4247 Seq. ID No. 4248 Signal peptide IM 2 2025 Seq. ID No. 4253 Seq. ID No. 4254 Signal peptide OM 1 2030a Seq. ID No. 4257 Seq. ID No. 4258 Signal peptide IM 4 2030b Seq. ID No. 4259 Seq. ID No. 4260 Signal peptide IM 5 2030c Seq. ID No. 4261 Seq. ID No. 4262 Signal peptide IM 5 2030d Seq. ID No. 4263 Seq. ID No. 4264 Signal peptide IM 5 2035b Seq. ID No. 4269 Seq. ID No. 4270 Signal peptide Cyto 0 2059a Seq. ID No. 4311 Seq. ID No. 4312 Signal peptide IM 2 2092 Seq. ID No. 4379 Seq. ID No. 4380 Signal peptide IM 2 2096c Seq. ID No. 4389 Seq. ID No. 4390 Signal peptide IM 10 2096d Seq. ID No. 4391 Seq. ID No. 4392 Signal peptide IM 10 2140b Seq. ID No. 4471 Seq. ID No. 4472 Non-secretory protein IM 5 2142a Seq. ID No. 4473 Seq. ID No. 4474 Signal peptide IM 1 2146 Seq. ID No. 4481 Seq. ID No. 4482 Signal peptide OM 1 2161a Seq. ID No. 4525 Seq. ID No. 4526 Non-secretory protein Cyto 1 2175 Seq. ID No. 4551 Seq. ID No. 4552 Non-secretory protein IM 2 2177b Seq. ID No. 4561 Seq. ID No. 4562 Non-secretory protein IM 1 2182 Seq. ID No. 4573 Seq. ID No. 4574 Non-secretory protein IM 1 2208a Seq. ID No. 4617 Seq. ID No. 4618 Non-secretory protein Cyto 0 2219a Seq. ID No. 4639 Seq. ID No. 4640 Signal peptide IM 1 2225 Seq. ID No. 4659 Seq. ID No. 4660 Signal peptide OM 0 2236a Seq. ID No. 4681 Seq. ID No. 4682 Signal peptide IM 2 2246 Seq. ID No. 4701 Seq. ID No. 4702 Non-secretory protein IM 2249 Seq. ID No. 4705 Seq. ID No. 4706 Signal peptide OM 1 2253d Seq. ID No. 4713 Seq. ID No. 4714 Non-secretory protein IM 7 2255b Seq. ID No. 4717 Seq. ID No. 4718 Signal peptide IM 6 2257 Seq. ID No. 4721 Seq. ID No. 4722 Non-secretory protein IM 0 2264b Seq. ID No. 4737 Seq. ID No. 4738 Signal peptide IM 1 2268 Seq. ID No. 4741 Seq. ID No. 4742 Non-secretory protein Cyto 0 2300 Seq. ID No. 4813 Seq. ID No. 4814 Signal peptide IM 4 2302 Seq. ID No. 4817 Seq. ID No. 4818 Non-secretory protein IM 1 2303 Seq. ID No. 4819 Seq. ID No. 4820 Non-secretory protein IM 1 2309a Seq. ID No. 4829 Seq. ID No. 4830 Non-secretory protein IM 2 2309b Seq. ID No. 4831 Seq. ID No. 4832 Non-secretory protein IM 2 2317 Seq. ID No. 4851 Seq. ID No. 4852 Non-secretory protein IM 2 2329a Seq. ID No. 4869 Seq. ID No. 4870 Signal peptide IM 1 2329d Seq. ID No. 4875 Seq. ID No. 4876 Signal peptide IM 7 2350a Seq. ID No. 4913 Seq. ID No. 4914 Non-secretory protein Cyto 2357 Seq. ID No. 4919 Seq. ID No. 4920 Signal peptide IM 2 2363a Seq. ID No. 4929 Seq. ID No. 4930 Signal peptide IM 1 2363b Seq. ID No. 4931 Seq. ID No. 4932 Signal peptide IM 1 2386c Seq. ID No. 4983 Seq. ID No. 4984 Non-secretory protein IM 0 2394 Seq. ID No. 4993 Seq. ID No. 4994 Non-secretory protein IM 1 2402a Seq. ID No. 5011 Seq. ID No. 5012 Non-secretory protein IM 1 2407a Seq. ID No. 5023 Seq. ID No. 5024 Non-secretory protein IM 0 2412 Seq. ID No. 5031 Seq. ID No. 5032 Signal peptide IM 2 2413a Seq. ID No. 5033 Seq. ID No. 5034 Non-secretory protein Cyto 0 2413b Seq. ID No. 5035 Seq. ID No. 5036 Non-secretory protein Peri 0 2416c Seq. ID No. 5043 Seq. ID No. 5044 Non-secretory protein IM 1 2423a Seq. ID No. 5061 Seq. ID No. 5062 Signal peptide IM 5 2423b Seq. ID No. 5063 Seq. ID No. 5064 Signal peptide IM 5 2424c Seq. ID No. 5069 Seq. ID No. 5070 Signal peptide IM 1 2445 Seq. ID No. 5103 Seq. ID No. 5104 Signal peptide IM 1 2456b Seq. ID No. 5121 Seq. ID No. 5122 Non-secretory protein IM 5 2456c Seq. ID No. 5123 Seq. ID No. 5124 Signal peptide IM 8 2458b Seq. ID No. 5131 Seq. ID No. 5132 Signal peptide IM 6 2458c Seq. ID No. 5133 Seq. ID No. 5134 Signal peptide IM 7 2458d Seq. ID No. 5135 Seq. ID No. 5136 Signal peptide IM 7 2458e Seq. ID No. 5137 Seq. ID No. 5138 Signal peptide IM 8 2458f Seq. ID No. 5139 Seq. ID No. 5140 Signal peptide IM 9 2458g Seq. ID No. 5141 Seq. ID No. 5142 Signal peptide IM 9 2463a Seq. ID No. 5151 Seq. ID No. 5152 Non-secretory protein IM 1 2468a Seq. ID No. 5159 Seq. ID No. 5160 Signal peptide IM 1 2468b Seq. ID No. 5161 Seq. ID No. 5162 Non-secretory protein IM 1 2469b Seq. ID No. 5165 Seq. ID No. 5166 Signal peptide IM 2 2470 Seq. ID No. 5167 Seq. ID No. 5168 Non-secretory protein Cyto 0 2474b Seq. ID No. 5175 Seq. ID No. 5176 Signal peptide IM 3 2474c Seq. ID No. 5177 Seq. ID No. 5178 Non-secretory protein IM 3 2490 Seq. ID No. 5205 Seq. ID No. 5206 Signal peptide IM 1 2492a Seq. ID No. 5207 Seq. ID No. 5208 Signal peptide IM 1 2494 Seq. ID No. 5211 Seq. ID No. 5212 Non-secretory protein IM 0 2495b Seq. ID No. 5215 Seq. ID No. 5216 Non-secretory protein IM 10 2497b Seq. ID No. 5219 Seq. ID No. 5220 Signal peptide Peri 2 2500a Seq. ID No. 5223 Seq. ID No. 5224 Signal peptide OM 1 2525a Seq. ID No. 5285 Seq. ID No. 5286 Signal peptide IM 1 2525b Seq. ID No. 5287 Seq. ID No. 5288 Non-secretory protein IM 1 2547b Seq. ID No. 5329 Seq. ID No. 5330 Signal peptide IM 1 2547c Seq. ID No. 5331 Seq. ID No. 5332 Signal peptide IM 1 2564b Seq. ID No. 5377 Seq. ID No. 5378 Signal peptide OM 1 2564c Seq. ID No. 5379 Seq. ID No. 5380 Signal peptide OM 1 2564d Seq. ID No. 5381 Seq. ID No. 5382 Non-secretory protein IM 1 2567a Seq. ID No. 5385 Seq. ID No. 5386 Signal peptide IM 4 2582a Seq. ID No. 5405 Seq. ID No. 5406 Signal peptide IM 4 2582b Seq. ID No. 5407 Seq. ID No. 5408 Non-secretory protein IM 4 2610 Seq. ID No. 5453 Seq. ID No. 5454 Signal peptide IM 1 2616a Seq. ID No. 5459 Seq. ID No. 5460 Signal peptide IM 2 2616b Seq. ID No. 5461 Seq. ID No. 5462 Signal peptide IM 3 2616c Seq. ID No. 5463 Seq. ID No. 5464 Signal peptide IM 4 2618b Seq. ID No. 5481 Seq. ID No. 5482 Non-secretory protein IM 2628 Seq. ID No. 5509 Seq. ID No. 5510 Signal peptide IM 1 2637a Seq. ID No. 5529 Seq. ID No. 5530 Signal peptide OM 1 2637b Seq. ID No. 5531 Seq. ID No. 5532 Signal peptide IM 1 2655b Seq. ID No. 5557 Seq. ID No. 5558 Non-secretory protein IM 1 2660 Seq. ID No. 5569 Seq. ID No. 5570 Signal peptide Peri 1 2665 Seq. ID No. 5577 Seq. ID No. 5578 Non-secretory protein IM 1 2683a Seq. ID No. 5623 Seq. ID No. 5624 Signal peptide IM 1 2683b Seq. ID No. 5625 Seq. ID No. 5626 Signal peptide IM 1 2690a Seq. ID No. 5643 Seq. ID No. 5644 Signal peptide Peri 1 2696a Seq. ID No. 5659 Seq. ID No. 5660 Signal peptide IM 8 2696b Seq. ID No. 5661 Seq. ID No. 5662 Non-secretory protein IM 8 2718b Seq. ID No. 5683 Seq. ID No. 5684 Signal peptide IM 3 2718c Seq. ID No. 5685 Seq. ID No. 5686 Signal peptide IM 4 2728a Seq. ID No. 5709 Seq. ID No. 5710 Signal peptide IM 1 2728b Seq. ID No. 5711 Seq. ID No. 5712 Signal peptide IM 1 2738c Seq. ID No. 5733 Seq. ID No. 5734 Signal peptide IM 12 2742b Seq. ID No. 5739 Seq. ID No. 5740 Signal peptide Peri 2749b Seq. ID No. 5765 Seq. ID No. 5766 Signal peptide IM 4 2760a Seq. ID No. 5797 Seq. ID No. 5798 Signal peptide Peri 1 2769a Seq. ID No. 5827 Seq. ID No. 5828 Non-secretory protein IM 0 2799a Seq. ID No. 5889 Seq. ID No. 5890 Signal peptide OM 1 2801a Seq. ID No. 5893 Seq. ID No. 5894 Signal peptide IM 1 2810a Seq. ID No. 5905 Seq. ID No. 5906 Signal peptide IM 3 2810c Seq. ID No. 5909 Seq. ID No. 5910 Signal peptide IM 4 2810d Seq. ID No. 5911 Seq. ID No. 5912 Non-secretory protein IM 4 2818b Seq. ID No. 5923 Seq. ID No. 5924 Signal peptide IM 5 2837a Seq. ID No. 5963 Seq. ID No. 5964 Non-secretory protein IM 2 2837b Seq. ID No. 5965 Seq. ID No. 5966 Non-secretory protein IM 3 2869b Seq. ID No. 6025 Seq. ID No. 6026 Signal peptide OM 1 2869c Seq. ID No. 6027 Seq. ID No. 6028 Signal peptide IM 1 2872 Seq. ID No. 6031 Seq. ID No. 6032 Non-secretory protein Cyto 2881 Seq. ID No. 6043 Seq. ID No. 6044 Signal peptide IM 1 2882 Seq. ID No. 6045 Seq. ID No. 6046 Non-secretory protein IM 2 2883a Seq. ID No. 6047 Seq. ID No. 6048 Signal peptide IM 6 2883d Seq. ID No. 6053 Seq. ID No. 6054 Signal peptide IM 8 2887a Seq. ID No. 6059 Seq. ID No. 6060 Signal peptide Peri 1 2909c Seq. ID No. 6109 Seq. ID No. 6110 Signal peptide IM 4 2909d Seq. ID No. 6111 Seq. ID No. 6112 Signal peptide IM 4 2913a Seq. ID No. 6115 Seq. ID No. 6116 Signal peptide IM 2 2913b Seq. ID No. 6117 Seq. ID No. 6118 Signal peptide IM 2 2917 Seq. ID No. 6127 Seq. ID No. 6128 Non-secretory protein OM 1 2920 Seq. ID No. 6131 Seq. ID No. 6132 Non-secretory protein IM 2 2922b Seq. ID No. 6135 Seq. ID No. 6136 Signal peptide Cyto 0 2923a Seq. ID No. 6137 Seq. ID No. 6138 Signal peptide Cyto 2931a Seq. ID No. 6161 Seq. ID No. 6162 Signal peptide IM 5 2931c Seq. ID No. 6165 Seq. ID No. 6166 Signal peptide IM 13 2941a Seq. ID No. 6183 Seq. ID No. 6184 Signal peptide IM 2 2943a Seq. ID No. 6189 Seq. ID No. 6190 Signal peptide IM 3 2943b Seq. ID No. 6191 Seq. ID No. 6192 Signal peptide IM 5 2943c Seq. ID No. 6193 Seq. ID No. 6194 Non-secretory protein IM 6 2948c Seq. ID No. 6207 Seq. ID No. 6208 Non-secretory protein IM 6 2948d Seq. ID No. 6209 Seq. ID No. 6210 Signal peptide IM 7 2952 Seq. ID No. 6217 Seq. ID No. 6218 Signal peptide Cyto 1 2955c Seq. ID No. 6225 Seq. ID No. 6226 Signal peptide IM 6 2957 Seq. ID No. 6235 Seq. ID No. 6236 Signal peptide IM 4 2959 Seq. ID No. 6243 Seq. ID No. 6244 Signal peptide IM 2 2962b Seq. ID No. 6249 Seq. ID No. 6250 Signal peptide IM 1 2965a Seq. ID No. 6253 Seq. ID No. 6254 Signal peptide Cyto 1 2966 Seq. ID No. 6259 Seq. ID No. 6260 Signal peptide IM 1 2970a Seq. ID No. 6265 Seq. ID No. 6266 Signal peptide IM 1 2970b Seq. ID No. 6267 Seq. ID No. 6268 Signal peptide IM 1 2974b Seq. ID No. 6275 Seq. ID No. 6276 Signal peptide IM 4 2978a Seq. ID No. 6283 Seq. ID No. 6284 Signal peptide Peri 1 2978b Seq. ID No. 6285 Seq. ID No. 6286 Signal peptide Peri 1 2986b Seq. ID No. 6303 Seq. ID No. 6304 Signal peptide IM 7 2993a Seq. ID No. 6325 Seq. ID No. 6326 Signal peptide OM 0 2993b Seq. ID No. 6327 Seq. ID No. 6328 Signal peptide OM 0 3016a Seq. ID No. 6363 Seq. ID No. 6364 Signal peptide IM 4 3016b Seq. ID No. 6365 Seq. ID No. 6366 Signal peptide IM 7 3016c Seq. ID No. 6367 Seq. ID No. 6368 Non-secretory protein IM 7 3024b Seq. ID No. 6385 Seq. ID No. 6386 Non-secretory protein Cyto 1 3042a Seq. ID No. 6425 Seq. ID No. 6426 Signal peptide Cyto 1 3042b Seq. ID No. 6427 Seq. ID No. 6428 Signal peptide Cyto 1 3043a Seq. ID No. 6429 Seq. ID No. 6430 Signal peptide IM 2 3043b Seq. ID No. 6431 Seq. ID No. 6432 Signal peptide IM 2 3054 Seq. ID No. 6453 Seq. ID No. 6454 Non-secretory protein Cyto 3061 Seq. ID No. 6465 Seq. ID No. 6466 Non-secretory protein Peri 1 3063a Seq. ID No. 6469 Seq. ID No. 6470 Non-secretory protein Cyto 0 3063b Seq. ID No. 6471 Seq. ID No. 6472 Non-secretory protein Cyto 0 3066 Seq. ID No. 6479 Seq. ID No. 6480 Signal peptide Cyto 0 3095 Seq. ID No. 6539 Seq. ID No. 6540 Non-secretory protein IM 1 3096a Seq. ID No. 6541 Seq. ID No. 6542 Signal peptide IM 1 3107a Seq. ID No. 6571 Seq. ID No. 6572 Signal peptide OM 1 3107b Seq. ID No. 6573 Seq. ID No. 6574 Signal peptide OM 2 3145c Seq. ID No. 6639 Seq. ID No. 6640 Signal peptide OM 1 3147b Seq. ID No. 6643 Seq. ID No. 6644 Signal peptide IM 0 3147c Seq. ID No. 6645 Seq. ID No. 6646 Signal peptide OM 0

Listed in Table 5 are 936 ORFs that meet the criteria of having a signal peptide based on the HMM SignalP program. Of these ORFs, the PSORT program predicted 71 ORFs to be localized to the periplasm (Peri); 93 ORFs to be localized to the outer membrane (OM); 663 ORFs to be localized to the cytoplasmic inner membrane (IM); and 109 ORFs to be localized to the cytoplasm. Shown for all ORFs is the predicted number of transmembrane domains predicted by the TopPred2 software (listed in the MSD column). TABLE 5 SIGNALP: SIGNAL PEPTIDE ORF DNA SEQ ID Protein SEQ ID Number Number Number SignalP PSORT MSD 2a Seq. ID No. 3 Seq. ID No. 4 NO IM 3 4a Seq. ID No. 7 Seq. ID No. 8 Yes IM 4 4b Seq. ID No. 9 Seq. ID No. 10 Maybe IM 10 11 Seq. ID No. 19 Seq. ID No. 20 maybe Cyto 0 13a Seq. ID No. 21 Seq. ID No. 22 NO Cyto 0 21b Seq. ID No. 31 Seq. ID No. 32 maybe Cyto 1 23a Seq. ID No. 33 Seq. ID No. 34 maybe IM 1 38a Seq. ID No. 45 Seq. ID No. 46 yes OM 1 38b Seq. ID No. 47 Seq. ID No. 48 yes OM 1 39a Seq. ID No. 49 Seq. ID No. 50 maybe IM 4 40 Seq. ID No. 53 Seq. ID No. 54 yes IM 1 44a Seq. ID No. 65 Seq. ID No. 66 yes IM 2 44b Seq. ID No. 67 Seq. ID No. 68 yes IM 2 51a Seq. ID No. 85 Seq. ID No. 86 maybe IM 5 51b Seq. ID No. 87 Seq. ID No. 88 yes IM 9 61 Seq. ID No. 105 Seq. ID No. 106 NO Cyto 2 62c Seq. ID No. 111 Seq. ID No. 112 NO IM 1 66a Seq. ID No. 123 Seq. ID No. 124 NO OM 1 73a Seq. ID No. 131 Seq. ID No. 132 YES Cyto 1 73b Seq. ID No. 133 Seq. ID No. 134 YES Cyto 1 80a Seq. ID No. 141 Seq. ID No. 142 maybe IM 4 86 Seq. ID No. 159 Seq. ID No. 160 yes Peri 1 87a Seq. ID No. 161 Seq. ID No. 162 YES OM 1 87b Seq. ID No. 163 Seq. ID No. 164 YES IM 1 91a Seq. ID No. 171 Seq. ID No. 172 maybe OM 0 99 Seq. ID No. 191 Seq. ID No. 192 maybe IM 10 109a Seq. ID No. 209 Seq. ID No. 210 maybe IM 5 109b Seq. ID No. 211 Seq. ID No. 212 yes IM 7 109c Seq. ID No. 213 Seq. ID No. 214 YES IM 8 109d Seq. ID No. 215 Seq. ID No. 216 YES IM 8 111a Seq. ID No. 217 Seq. ID No. 218 yes IM 6 114 Seq. ID No. 225 Seq. ID No. 226 YES OM 1 124a Seq. ID No. 235 Seq. ID No. 236 yes IM 1 124b Seq. ID No. 237 Seq. ID No. 238 yes IM 3 129a Seq. ID No. 249 Seq. ID No. 250 YES IM 6 129b Seq. ID No. 251 Seq. ID No. 252 YES IM 9 132a Seq. ID No. 255 Seq. ID No. 256 maybe IM 2 132b Seq. ID No. 257 Seq. ID No. 258 maybe IM 2 132c Seq. ID No. 259 Seq. ID No. 260 maybe IM 2 138a Seq. ID No. 271 Seq. ID No. 272 yes IM 6 138b Seq. ID No. 273 Seq. ID No. 274 maybe IM 6 143 Seq. ID No. 277 Seq. ID No. 278 maybe IM 2 145a Seq. ID No. 285 Seq. ID No. 286 yes IM 3 145b Seq. ID No. 287 Seq. ID No. 288 YES IM 10 145c Seq. ID No. 289 Seq. ID No. 290 YES IM 12 162a Seq. ID No. 327 Seq. ID No. 328 yes IM 2 162b Seq. ID No. 329 Seq. ID No. 330 maybe IM 3 173 Seq. ID No. 357 Seq. ID No. 358 maybe IM 1 174 Seq. ID No. 359 Seq. ID No. 360 maybe Peri 1 180a Seq. ID No. 373 Seq. ID No. 374 maybe IM 2 180b Seq. ID No. 375 Seq. ID No. 376 YES IM 10 191b Seq. ID No. 393 Seq. ID No. 394 maybe IM 1 194a Seq. ID No. 401 Seq. ID No. 402 maybe Cyto 1 194b Seq. ID No. 403 Seq. ID No. 404 maybe Cyto 1 223a Seq. ID No. 455 Seq. ID No. 456 yes Cyto 1 223b Seq. ID No. 457 Seq. ID No. 458 yes Cyto 1 235a Seq. ID No. 477 Seq. ID No. 478 maybe Cyto 0 239a Seq. ID No. 487 Seq. ID No. 488 NO Cyto 2 239b Seq. ID No. 489 Seq. ID No. 490 NO Cyto 2 239c Seq. ID No. 491 Seq. ID No. 492 NO Cyto 2 240 Seq. ID No. 493 Seq. ID No. 494 maybe Cyto 241 Seq. ID No. 495 Seq. ID No. 496 yes IM 1 245a Seq. ID No. 497 Seq. ID No. 498 YES IM 5 245b Seq. ID No. 499 Seq. ID No. 500 yes IM 10 246a Seq. ID No. 503 Seq. ID No. 504 YES IM 7 246b Seq. ID No. 505 Seq. ID No. 506 YES IM 9 248a Seq. ID No. 509 Seq. ID No. 510 maybe IM 8 248b Seq. ID No. 511 Seq. ID No. 512 yes IM 9 249a Seq. ID No. 513 Seq. ID No. 514 yes OM 1 249b Seq. ID No. 515 Seq. ID No. 516 yes IM 1 255a Seq. ID No. 525 Seq. ID No. 526 yes IM 6 255b Seq. ID No. 527 Seq. ID No. 528 YES IM 10 263a Seq. ID No. 545 Seq. ID No. 546 yes OM 1 263b Seq. ID No. 547 Seq. ID No. 548 yes IM 1 264b Seq. ID No. 549 Seq. ID No. 550 YES IM 1 268 Seq. ID No. 557 Seq. ID No. 558 yes Cyto 1 273a Seq. ID No. 567 Seq. ID No. 568 maybe IM 8 273b Seq. ID No. 569 Seq. ID No. 570 yes IM 12 277c Seq. ID No. 575 Seq. ID No. 576 YES OM 1 279a Seq. ID No. 577 Seq. ID No. 578 maybe IM 3 279b Seq. ID No. 579 Seq. ID No. 580 maybe IM 5 283a Seq. ID No. 591 Seq. ID No. 592 yes OM 1 283b Seq. ID No. 593 Seq. ID No. 594 yes OM 1 285b Seq. ID No. 599 Seq. ID No. 600 maybe Cyto 297 Seq. ID No. 617 Seq. ID No. 618 YES Peri 1 311 Seq. ID No. 637 Seq. ID No. 638 yes IM 6 313a Seq. ID No. 639 Seq. ID No. 640 yes IM 2 313b Seq. ID No. 641 Seq. ID No. 642 yes IM 3 313c Seq. ID No. 643 Seq. ID No. 644 maybe IM 6 313d Seq. ID No. 645 Seq. ID No. 646 maybe IM 6 313e Seq. ID No. 647 Seq. ID No. 648 maybe IM 6 317a Seq. ID No. 653 Seq. ID No. 654 yes IM 2 317b Seq. ID No. 655 Seq. ID No. 656 maybe IM 4 318a Seq. ID No. 657 Seq. ID No. 658 YES OM 2 318b Seq. ID No. 659 Seq. ID No. 660 YES OM 2 318c Seq. ID No. 661 Seq. ID No. 662 YES IM 2 320 Seq. ID No. 667 Seq. ID No. 668 maybe Cyto 1 321 Seq. ID No. 669 Seq. ID No. 670 yes OM 1 324 Seq. ID No. 675 Seq. ID No. 676 YES OM 1 327a Seq. ID No. 677 Seq. ID No. 678 maybe IM 3 327b Seq. ID No. 679 Seq. ID No. 680 yes IM 5 342a Seq. ID No. 715 Seq. ID No. 716 YES IM 2 342b Seq. ID No. 717 Seq. ID No. 718 YES IM 3 342c Seq. ID No. 719 Seq. ID No. 720 yes IM 4 342d Seq. ID No. 721 Seq. ID No. 722 NO IM 6 342e Seq. ID No. 723 Seq. ID No. 724 yes IM 10 342f Seq. ID No. 725 Seq. ID No. 726 NO IM 12 349b Seq. ID No. 745 Seq. ID No. 746 YES OM 1 349c Seq. ID No. 747 Seq. ID No. 748 YES OM 1 350a Seq. ID No. 749 Seq. ID No. 750 yes IM 6 350b Seq. ID No. 751 Seq. ID No. 752 yes IM 6 352a Seq. ID No. 755 Seq. ID No. 756 YES IM 3 352b Seq. ID No. 757 Seq. ID No. 758 YES IM 3 352c Seq. ID No. 759 Seq. ID No. 760 YES IM 6 354a Seq. ID No. 761 Seq. ID No. 762 YES IM 4 354b Seq. ID No. 763 Seq. ID No. 764 yes IM 6 354c Seq. ID No. 765 Seq. ID No. 766 yes IM 6 356a Seq. ID No. 769 Seq. ID No. 770 yes IM 3 358a Seq. ID No. 777 Seq. ID No. 778 yes IM 3 358b Seq. ID No. 779 Seq. ID No. 780 yes IM 10 358c Seq. ID No. 781 Seq. ID No. 782 yes IM 10 372d Seq. ID No. 807 Seq. ID No. 808 YES OM 1 374 Seq. ID No. 809 Seq. ID No. 810 NO IM 1 382b Seq. ID No. 819 Seq. ID No. 820 yes OM 1 384a Seq. ID No. 825 Seq. ID No. 826 maybe IM 2 403b Seq. ID No. 863 Seq. ID No. 864 NO Peri 2 418a Seq. ID No. 893 Seq. ID No. 894 NO IM 5 419c Seq. ID No. 901 Seq. ID No. 902 NO IM 2 431 Seq. ID No. 935 Seq. ID No. 936 yes OM 1 434 Seq. ID No. 937 Seq. ID No. 938 yes IM 2 437b Seq. ID No. 941 Seq. ID No. 942 maybe Cyto 1 437c Seq. ID No. 943 Seq. ID No. 944 maybe Cyto 1 441b Seq. ID No. 955 Seq. ID No. 956 yes IM 2 443b Seq. ID No. 957 Seq. ID No. 958 maybe Cyto 448 Seq. ID No. 967 Seq. ID No. 968 YES IM 1 452b Seq. ID No. 979 Seq. ID No. 980 yes IM 4 452c Seq. ID No. 981 Seq. ID No. 982 yes IM 4 452d Seq. ID No. 983 Seq. ID No. 984 yes IM 4 452e Seq. ID No. 985 Seq. ID No. 986 yes IM 4 460b Seq. ID No. 1001 Seq. ID No. 1002 maybe Cyto 1 460c Seq. ID No. 1003 Seq. ID No. 1004 maybe Cyto 1 462 Seq. ID No. 1005 Seq. ID No. 1006 yes Peri 1 463a Seq. ID No. 1007 Seq. ID No. 1008 yes Peri 1 463b Seq. ID No. 1009 Seq. ID No. 1010 yes Peri 1 464a Seq. ID No. 1011 Seq. ID No. 1012 maybe IM 2 464b Seq. ID No. 1013 Seq. ID No. 1014 YES IM 9 464c Seq. ID No. 1015 Seq. ID No. 1016 yes IM 11 465b Seq. ID No. 1019 Seq. ID No. 1020 yes OM 3 472a Seq. ID No. 1029 Seq. ID No. 1030 yes IM 4 472b Seq. ID No. 1031 Seq. ID No. 1032 yes IM 5 472c Seq. ID No. 1033 Seq. ID No. 1034 maybe IM 7 472d Seq. ID No. 1035 Seq. ID No. 1036 maybe IM 8 472e Seq. ID No. 1037 Seq. ID No. 1038 maybe IM 8 472f Seq. ID No. 1039 Seq. ID No. 1040 YES IM 10 476 Seq. ID No. 1045 Seq. ID No. 1046 maybe Peri 1 480a Seq. ID No. 1055 Seq. ID No. 1056 NO IM 1 492 Seq. ID No. 1075 Seq. ID No. 1076 YES OM 1 494a Seq. ID No. 1077 Seq. ID No. 1078 NO Cyto 1 507a Seq. ID No. 1105 Seq. ID No. 1106 maybe IM 1 507b Seq. ID No. 1107 Seq. ID No. 1108 maybe IM 1 521b Seq. ID No. 1131 Seq. ID No. 1132 maybe Cyto 2 524a Seq. ID No. 1135 Seq. ID No. 1136 maybe IM 1 524b Seq. ID No. 1137 Seq. ID No. 1138 yes IM 6 525 Seq. ID No. 1139 Seq. ID No. 1140 maybe Cyto 1 530a Seq. ID No. 1151 Seq. ID No. 1152 yes IM 541a Seq. ID No. 1165 Seq. ID No. 1166 maybe IM 2 541b Seq. ID No. 1167 Seq. ID No. 1168 maybe IM 4 541c Seq. ID No. 1169 Seq. ID No. 1170 yes IM 5 542 Seq. ID No. 1173 Seq. ID No. 1174 yes IM 1 545a Seq. ID No. 1183 Seq. ID No. 1184 yes IM 3 547a Seq. ID No. 1195 Seq. ID No. 1196 YES OM 1 547b Seq. ID No. 1197 Seq. ID No. 1198 YES IM 1 550a Seq. ID No. 1203 Seq. ID No. 1204 maybe IM 1 556 Seq. ID No. 1213 Seq. ID No. 1214 yes IM 2 561 Seq. ID No. 1223 Seq. ID No. 1224 yes IM 5 564a Seq. ID No. 1227 Seq. ID No. 1228 NO IM 4 564b Seq. ID No. 1229 Seq. ID No. 1230 yes IM 4 570b Seq. ID No. 1237 Seq. ID No. 1238 NO IM 5 576a Seq. ID No. 1243 Seq. ID No. 1244 YES Peri 1 576b Seq. ID No. 1245 Seq. ID No. 1246 YES IM 1 585b Seq. ID No. 1259 Seq. ID No. 1260 yes Cyto 0 587a Seq. ID No. 1265 Seq. ID No. 1266 maybe IM 4 587b Seq. ID No. 1267 Seq. ID No. 1268 NO IM 5 587c Seq. ID No. 1269 Seq. ID No. 1270 YES IM 9 587d Seq. ID No. 1271 Seq. ID No. 1272 NO IM 12 595a Seq. ID No. 1283 Seq. ID No. 1284 yes IM 2 596a Seq. ID No. 1287 Seq. ID No. 1288 maybe IM 1 596b Seq. ID No. 1289 Seq. ID No. 1290 maybe IM 2 596c Seq. ID No. 1291 Seq. ID No. 1292 maybe IM 2 598a Seq. ID No. 1295 Seq. ID No. 1296 maybe IM 2 598b Seq. ID No. 1297 Seq. ID No. 1298 maybe IM 2 600a Seq. ID No. 1303 Seq. ID No. 1304 maybe Peri 1 600b Seq. ID No. 1305 Seq. ID No. 1306 maybe Peri 1 609a Seq. ID No. 1315 Seq. ID No. 1316 YES IM 2 609b Seq. ID No. 1317 Seq. ID No. 1318 YES IM 2 610a Seq. ID No. 1319 Seq. ID No. 1320 yes IM 1 613a Seq. ID No. 1325 Seq. ID No. 1326 maybe IM 6 613b Seq. ID No. 1327 Seq. ID No. 1328 yes IM 7 613c Seq. ID No. 1329 Seq. ID No. 1330 NO IM 9 613d Seq. ID No. 1331 Seq. ID No. 1332 YES IM 10 615b Seq. ID No. 1337 Seq. ID No. 1338 maybe IM 2 619a Seq. ID No. 1341 Seq. ID No. 1342 yes Cyto 1 619b Seq. ID No. 1343 Seq. ID No. 1344 yes Cyto 1 623 Seq. ID No. 1347 Seq. ID No. 1348 yes Peri 1 624a Seq. ID No. 1349 Seq. ID No. 1350 NO IM 1 624b Seq. ID No. 1351 Seq. ID No. 1352 maybe IM 1 624c Seq. ID No. 1353 Seq. ID No. 1354 maybe IM 1 631b Seq. ID No. 1365 Seq. ID No. 1366 YES IM 2 631c Seq. ID No. 1367 Seq. ID No. 1368 YES IM 2 631d Seq. ID No. 1369 Seq. ID No. 1370 YES IM 2 632b Seq. ID No. 1371 Seq. ID No. 1372 maybe IM 1 636 Seq. ID No. 1381 Seq. ID No. 1382 maybe Cyto 645 Seq. ID No. 1401 Seq. ID No. 1402 yes Peri 1 665 Seq. ID No. 1429 Seq. ID No. 1430 yes IM 3 674a Seq. ID No. 1435 Seq. ID No. 1436 NO IM 1 679a Seq. ID No. 1445 Seq. ID No. 1446 YES Cyto 1 679b Seq. ID No. 1447 Seq. ID No. 1448 YES IM 1 700a Seq. ID No. 1481 Seq. ID No. 1482 NO IM 2 722a Seq. ID No. 1513 Seq. ID No. 1514 YES IM 3 722b Seq. ID No. 1515 Seq. ID No. 1516 maybe IM 7 722c Seq. ID No. 1517 Seq. ID No. 1518 YES IM 11 728a Seq. ID No. 1529 Seq. ID No. 1530 NO IM 6 730a Seq. ID No. 1533 Seq. ID No. 1534 NO IM 3 730b Seq. ID No. 1535 Seq. ID No. 1536 maybe IM 5 738a Seq. ID No. 1545 Seq. ID No. 1546 YES IM 2 738b Seq. ID No. 1547 Seq. ID No. 1548 NO IM 9 739 Seq. ID No. 1551 Seq. ID No. 1552 yes IM 2 740 Seq. ID No. 1553 Seq. ID No. 1554 NO OM 0 743a Seq. ID No. 1559 Seq. ID No. 1560 yes IM 2 743b Seq. ID No. 1561 Seq. ID No. 1562 YES IM 2 744 Seq. ID No. 1563 Seq. ID No. 1564 maybe OM 1 746b Seq. ID No. 1571 Seq. ID No. 1572 YES IM 6 749 Seq. ID No. 1579 Seq. ID No. 1580 yes IM 1 754a Seq. ID No. 1583 Seq. ID No. 1584 NO IM 3 754b Seq. ID No. 1585 Seq. ID No. 1586 YES IM 9 772a Seq. ID No. 1621 Seq. ID No. 1622 yes IM 5 779 Seq. ID No. 1633 Seq. ID No. 1634 yes Peri 2 782b Seq. ID No. 1639 Seq. ID No. 1640 NO IM 5 786b Seq. ID No. 1643 Seq. ID No. 1644 YES Peri 1 788a Seq. ID No. 1645 Seq. ID No. 1646 yes IM 4 788b Seq. ID No. 1647 Seq. ID No. 1648 yes IM 6 789a Seq. ID No. 1649 Seq. ID No. 1650 yes IM 4 789c Seq. ID No. 1653 Seq. ID No. 1654 YES IM 5 794b Seq. ID No. 1661 Seq. ID No. 1662 YES OM 0 794c Seq. ID No. 1663 Seq. ID No. 1664 YES OM 0 794d Seq. ID No. 1665 Seq. ID No. 1666 yes OM 0 799a Seq. ID No. 1671 Seq. ID No. 1672 yes IM 2 799b Seq. ID No. 1673 Seq. ID No. 1674 maybe IM 4 799d Seq. ID No. 1677 Seq. ID No. 1678 yes IM 9 799e Seq. ID No. 1679 Seq. ID No. 1680 yes IM 10 799f Seq. ID No. 1681 Seq. ID No. 1682 yes IM 10 808 Seq. ID No. 1693 Seq. ID No. 1694 NO Cyto 826 Seq. ID No. 1707 Seq. ID No. 1708 YES IM 3 829b Seq. ID No. 1711 Seq. ID No. 1712 NO Peri 837a Seq. ID No. 1731 Seq. ID No. 1732 yes IM 2 837b Seq. ID No. 1733 Seq. ID No. 1734 YES IM 8 843 Seq. ID No. 1737 Seq. ID No. 1738 YES IM 1 853a Seq. ID No. 1753 Seq. ID No. 1754 yes IM 3 853b Seq. ID No. 1755 Seq. ID No. 1756 YES IM 5 853c Seq. ID No. 1757 Seq. ID No. 1758 maybe IM 5 859a Seq. ID No. 1765 Seq. ID No. 1766 YES IM 2 859b Seq. ID No. 1767 Seq. ID No. 1768 YES IM 4 859d Seq. ID No. 1771 Seq. ID No. 1772 NO IM 6 864b Seq. ID No. 1781 Seq. ID No. 1782 maybe Cyto 1 868a Seq. ID No. 1787 Seq. ID No. 1788 yes IM 3 870 Seq. ID No. 1791 Seq. ID No. 1792 YES OM 1 873c Seq. ID No. 1797 Seq. ID No. 1798 yes OM 1 876 Seq. ID No. 1805 Seq. ID No. 1806 YES Peri 1 885 Seq. ID No. 1819 Seq. ID No. 1820 NO IM 2 886 Seq. ID No. 1821 Seq. ID No. 1822 yes OM 1 887 Seq. ID No. 1823 Seq. ID No. 1824 yes IM 1 908a Seq. ID No. 1839 Seq. ID No. 1840 yes IM 6 919 Seq. ID No. 1857 Seq. ID No. 1858 maybe Cyto 929a Seq. ID No. 1869 Seq. ID No. 1870 maybe Cyto 1 931 Seq. ID No. 1875 Seq. ID No. 1876 YES IM 2 939a Seq. ID No. 1891 Seq. ID No. 1892 maybe IM 9 939b Seq. ID No. 1893 Seq. ID No. 1894 yes IM 10 939c Seq. ID No. 1895 Seq. ID No. 1896 NO IM 12 950 Seq. ID NO. 1915 Seq. ID No. 1916 NO IM 1 951a Seq. ID No. 1917 Seq. ID No. 1918 yes OM 0 951b Seq. ID No. 1919 Seq. ID No. 1920 yes IM 0 952b Seq. ID No. 1923 Seq. ID No. 1924 maybe IM 4 955a Seq. ID No. 1927 Seq. ID No. 1928 maybe IM 1 955b Seq. ID No. 1929 Seq. ID No. 1930 maybe IM 1 977a Seq. ID No. 1969 Seq. ID No. 1970 YES OM 1 981a Seq. ID No. 1981 Seq. ID No. 1982 YES IM 1 987 Seq. ID No. 1991 Seq. ID No. 1992 yes IM 5 988a Seq. ID No. 1993 Seq. ID No. 1994 NO IM 5 993 Seq. ID No. 2005 Seq. ID No. 2006 maybe IM 0 998a Seq. ID No. 2013 Seq. ID No. 2014 yes IM 5 999a Seq. ID No. 2017 Seq. ID No. 2018 yes IM 2 999b Seq. ID No. 2019 Seq. ID No. 2020 yes IM 2 1003a Seq. ID No. 2025 Seq. ID No. 2026 maybe IM 2 1003b Seq. ID No. 2027 Seq. ID No. 2028 maybe IM 2 1006a Seq. ID No. 2033 Seq. ID No. 2034 yes Peri 1 1006b Seq. ID No. 2035 Seq. ID No. 2036 yes Cyto 1 1013a Seq. ID No. 2041 Seq. ID No. 2042 maybe IM 5 1017a Seq. ID No. 2049 Seq. ID No. 2050 yes IM 4 1017c Seq. ID No. 2053 Seq. ID No. 2054 YES IM 6 1017d Seq. ID No. 2055 Seq. ID No. 2056 YES IM 6 1036a Seq. ID No. 2087 Seq. ID No. 2088 YES IM 3 1036b Seq. ID No. 2089 Seq. ID No. 2090 YES IM 4 1036c Seq. ID No. 2091 Seq. ID No. 2092 YES IM 4 1044a Seq. ID No. 2105 Seq. ID No. 2106 YES IM 2 1044b Seq. ID No. 2107 Seq. ID No. 2108 maybe IM 3 1044c Seq. ID No. 2109 Seq. ID No. 2110 maybe IM 3 1047a Seq. ID No. 2113 Seq. ID No. 2114 yes OM 1 1047b Seq. ID No. 2115 Seq. ID No. 2116 YES OM 1 1050a Seq. ID No. 2121 Seq. ID No. 2122 maybe IM 3 1050b Seq. ID No. 2123 Seq. ID No. 2124 yes IM 7 1050c Seq. ID No. 2125 Seq. ID No. 2126 yes IM 7 1050d Seq. ID No. 2127 Seq. ID No. 2128 yes IM 7 1065a Seq. ID No. 2149 Seq. ID No. 2150 YES Peri 1 1065b Seq. ID No. 2151 Seq. ID No. 2152 YES Peri 1 1066a Seq. ID No. 2155 Seq. ID No. 2156 NO IM 1 1066b Seq. ID No. 2157 Seq. ID No. 2158 NO IM 1 1067 Seq. ID No. 2159 Seq. ID No. 2160 YES OM 1 1077a Seq. ID No. 2171 Seq. ID No. 2172 yes IM 3 1077b Seq. ID No. 2173 Seq. ID No. 2174 maybe IM 10 1077d Seq. ID No. 2177 Seq. ID No. 2178 YES IM 13 1081a Seq. ID No. 2187 Seq. ID No. 2188 yes Peri 1 1082 Seq. ID No. 2191 Seq. ID No. 2192 maybe Peri 0 1094a Seq. ID No. 2205 Seq. ID No. 2206 maybe IM 2 1111a Seq. ID No. 2237 Seq. ID No. 2238 yes IM 6 1111b Seq. ID No. 2239 Seq. ID No. 2240 maybe IM 8 1125 Seq. ID No. 2245 Seq. ID No. 2246 NO IM 4 1126b Seq. ID No. 2249 Seq. ID No. 2250 yes IM 4 1126c Seq. ID No. 2251 Seq. ID No. 2252 yes IM 4 1128 Seq. ID No. 2255 Seq. ID No. 2256 yes IM 2 1132 Seq. ID No. 2259 Seq. ID No. 2260 NO Cyto 1140a Seq. ID No. 2271 Seq. ID No. 2272 yes IM 2 1144a Seq. ID No. 2283 Seq. ID No. 2284 yes IM 2 1146a Seq. ID No. 2289 Seq. ID No. 2290 yes IM 3 1146b Seq. ID No. 2291 Seq. ID No. 2292 NO IM 5 1146c Seq. ID No. 2293 Seq. ID No. 2294 YES IM 7 1146d Seq. ID No. 2295 Seq. ID No. 2296 yes IM 8 1152a Seq. ID No. 2303 Seq. ID No. 2304 maybe IM 2 1152b Seq. ID No. 2305 Seq. ID No. 2306 yes IM 5 1152c Seq. ID No. 2307 Seq. ID No. 2308 yes IM 6 1155a Seq. ID No. 2317 Seq. ID No. 2318 yes IM 3 1155b Seq. ID No. 2319 Seq. ID No. 2320 yes IM 4 1155c Seq. ID No. 2321 Seq. ID No. 2322 YES IM 5 1155d Seq. ID No. 2323 Seq. ID No. 2324 yes IM 6 1155e Seq. ID No. 2325 Seq. ID No. 2326 yes IM 9 1155f Seq. ID No. 2327 Seq. ID No. 2328 maybe IM 11 1155g Seq. ID No. 2329 Seq. ID No. 2330 maybe IM 11 1158b Seq. ID No. 2333 Seq. ID No. 2334 maybe Cyto 1 1165 Seq. ID No. 2343 Seq. ID No. 2344 yes OM 1 1167a Seq. ID No. 2347 Seq. ID No. 2348 YES Peri 1 1167b Seq. ID No. 2349 Seq. ID No. 2350 yes IM 2 1168 Seq. ID No. 2351 Seq. ID No. 2352 YES Peri 1 1169a Seq. ID No. 2353 Seq. ID No. 2354 YES IM 4 1169b Seq. ID No. 2355 Seq. ID No. 2356 maybe IM 6 1169c Seq. ID No. 2357 Seq. ID No. 2358 maybe IM 8 1172 Seq. ID No. 2365 Seq. ID No. 2366 YES IM 1 1173 Seq. ID No. 2367 Seq. ID No. 2368 maybe IM 2 1175 Seq. ID No. 2371 Seq. ID No. 2372 maybe Cyto 0 1178 Seq. ID No. 2375 Seq. ID No. 2376 maybe Cyto 1 1180c Seq. ID No. 2387 Seq. ID No. 2388 maybe IM 3 1180d Seq. ID No. 2389 Seq. ID No. 2390 maybe IM 3 1180e Seq. ID No. 2391 Seq. ID No. 2392 maybe IM 4 1182a Seq. ID No. 2393 Seq. ID No. 2394 yes IM 1 1186a Seq. ID No. 2407 Seq. ID No. 2408 maybe IM 5 1192a Seq. ID No. 2419 Seq. ID No. 2420 maybe IM 3 1192b Seq. ID No. 2421 Seq. ID No. 2422 YES IM 4 1196a Seq. ID No. 2425 Seq. ID No. 2426 YES Peri 1 1196b Seq. ID No. 2427 Seq. ID No. 2428 YES Peri 1 1197 Seq. ID No. 2429 Seq. ID No. 2430 YES IM 2 1199a Seq. ID No. 2433 Seq. ID No. 2434 maybe IM 3 1207 Seq. ID No. 2449 Seq. ID No. 2450 YES OM 1 1212 Seq. ID No. 2459 Seq. ID No. 2460 YES IM 2 1224a Seq. ID No. 2487 Seq. ID No. 2488 maybe IM 6 1224b Seq. ID No. 2489 Seq. ID No. 2490 maybe IM 6 1224c Seq. ID No. 2491 Seq. ID No. 2492 yes IM 6 1225 Seq. ID No. 2493 Seq. ID No. 2494 NO Cyto 1 1228a Seq. ID No. 2497 Seq. ID No. 2498 yes IM 1 1228b Seq. ID No. 2499 Seq. ID No. 2500 yes IM 2 1229b Seq. ID No. 2501 Seq. ID No. 2502 NO Cyto 2 1229c Seq. ID No. 2503 Seq. ID No. 2504 NO Cyto 2 1231 Seq. ID No. 2507 Seq. ID No. 2508 yes OM 1 1234a Seq. ID No. 2515 Seq. ID No. 2516 yes IM 4 1234b Seq. ID No. 2517 Seq. ID No. 2518 yes IM 4 1236a Seq. ID No. 2523 Seq. ID No. 2524 yes IM 2 1237 Seq. ID No. 2525 Seq. ID No. 2526 YES OM 1 1239 Seq. ID No. 2527 Seq. ID No. 2528 yes OM 1 1241a Seq. ID No. 2531 Seq. ID No. 2532 YES IM 2 1241b Seq. ID No. 2533 Seq. ID No. 2534 yes IM 7 1241c Seq. ID No. 2535 Seq. ID No. 2536 yes IM 7 1243 Seq. ID No. 2537 Seq. ID No. 2538 maybe IM 4 1245a Seq. ID No. 2541 Seq. ID No. 2542 yes IM 6 1245b Seq. ID No. 2543 Seq. ID No. 2544 yes IM 10 1245c Seq. ID No. 2545 Seq. ID No. 2546 maybe IM 11 1250a Seq. ID No. 2555 Seq. ID No. 2556 maybe IM 2 1250b Seq. ID No. 2557 Seq. ID No. 2558 yes IM 8 1251a Seq. ID No. 2565 Seq. ID No. 2566 maybe IM 3 1253a Seq. ID No. 2569 Seq. ID No. 2570 maybe OM 1 1253b Seq. ID No. 2571 Seq. ID No. 2572 maybe OM 2 1258a Seq. ID No. 2583 Seq. ID No. 2584 yes IM 5 1260 Seq. ID No. 2591 Seq. ID No. 2592 maybe Cyto 1 1266a Seq. ID No. 2597 Seq. ID No. 2598 NO IM 6 1266b Seq. ID No. 2599 Seq. ID No. 2600 maybe IM 7 1267a Seq. ID No. 2601 Seq. ID No. 2602 yes IM 2 1268b Seq. ID No. 2607 Seq. ID No. 2608 YES IM 5 1270 Seq. ID No. 2611 Seq. ID No. 2612 maybe IM 2 1275a Seq. ID No. 2621 Seq. ID No. 2622 yes Cyto 1 1278a Seq. ID No. 2627 Seq. ID No. 2628 NO IM 1 1278b Seq. ID No. 2629 Seq. ID No. 2630 NO IM 2 1288 Seq. ID No. 2651 Seq. ID No. 2652 YES IM 1 1308a Seq. ID No. 2679 Seq. ID No. 2680 YES IM 3 1308b Seq. ID No. 2681 Seq. ID No. 2682 yes IM 4 1308c Seq. ID No. 2683 Seq. ID No. 2684 maybe IM 4 1314b Seq. ID No. 2691 Seq. ID No. 2692 yes IM 1 1315 Seq. ID No. 2693 Seq. ID No. 2694 YES IM 2 1316 Seq. ID No. 2695 Seq. ID No. 2696 maybe IM 1317 Seq. ID No. 2697 Seq. ID No. 2698 NO Cyto 1 1318 Seq. ID No. 2699 Seq. ID No. 2700 YES IM 0 1319a Seq. ID No. 2701 Seq. ID No. 2702 yes IM 4 1319b Seq. ID No. 2703 Seq. ID No. 2704 YES IM 5 1320a Seq. ID No. 2705 Seq. ID No. 2706 maybe IM 2 1320b Seq. ID No. 2707 Seq. ID No. 2708 NO IM 4 1323b Seq. ID No. 2717 Seq. ID No. 2718 maybe OM 1 1334a Seq. ID No. 2729 Seq. ID No. 2730 maybe IM 2 1334b Seq. ID No. 2731 Seq. ID No. 2732 maybe OM 2 1335a Seq. ID No. 2733 Seq. ID No. 2734 yes OM 2 1365b Seq. ID No. 2783 Seq. ID No. 2784 maybe IM 2 1366a Seq. ID No. 2785 Seq. ID No. 2786 YES Peri 1 1375 Seq. ID No. 2801 Seq. ID No. 2802 yes Cyto 0 1380 Seq. ID No. 2809 Seq. ID No. 2810 NO IM 2 1381b Seq. ID No. 2813 Seq. ID No. 2814 YES IM 2 1382 Seq. ID No. 2815 Seq. ID No. 2816 yes OM 1 1384a Seq. ID No. 2819 Seq. ID No. 2820 yes IM 2 1384b Seq. ID No. 2821 Seq. ID No. 2822 yes IM 2 1384c Seq. ID No. 2823 Seq. ID No. 2824 yes IM 2 1388b Seq. ID No. 2831 Seq. ID No. 2832 maybe Cyto 1389a Seq. ID No. 2833 Seq. ID No. 2834 yes Cyto 0 1393a Seq. ID No. 2835 Seq. ID No. 2836 YES Peri 1 1393b Seq. ID No. 2837 Seq. ID No. 2838 yes IM 2 1393c Seq. ID No. 2839 Seq. ID No. 2840 yes IM 3 1393d Seq. ID No. 2841 Seq. ID No. 2842 YES IM 3 1395a Seq. ID No. 2845 Seq. ID No. 2846 yes Cyto 1399a Seq. ID No. 2853 Seq. ID No. 2854 yes IM 2 1399b Seq. ID No. 2855 Seq. ID No. 2856 maybe IM 2 1401 Seq. ID No. 2859 Seq. ID No. 2860 NO IM 1 1402c Seq. ID No. 2861 Seq. ID No. 2862 yes IM 2 1411a Seq. ID No. 2873 Seq. ID No. 2874 yes IM 3 1412b Seq. ID No. 2881 Seq. ID No. 2882 YES IM 9 1418 Seq. ID No. 2893 Seq. ID No. 2894 maybe Cyto 1426a Seq. ID No. 2905 Seq. ID No. 2906 yes IM 4 1438 Seq. ID No. 2935 Seq. ID No. 2936 YES OM 1 1439a Seq. ID No. 2937 Seq. ID No. 2938 YES IM 3 1439b Seq. ID No. 2939 Seq. ID No. 2940 yes IM 5 1439c Seq. ID No. 2941 Seq. ID No. 2942 yes IM 6 1440a Seq. ID No. 2947 Seq. ID No. 2948 yes IM 6 1440b Seq. ID No. 2949 Seq. ID No. 2950 YES IM 10 1440c Seq. ID No. 2951 Seq. ID No. 2952 maybe IM 12 1447a Seq. ID No. 2969 Seq. ID No. 2970 NO IM 10 1448 Seq. ID No. 2973 Seq. ID No. 2974 YES IM 1 1449a Seq. ID No. 2975 Seq. ID No. 2976 maybe OM 1 1449b Seq. ID No. 2977 Seq. ID No. 2978 maybe OM 1 1452a Seq. ID No. 2981 Seq. ID No. 2982 yes IM 4 1452b Seq. ID No. 2983 Seq. ID No. 2984 yes IM 4 1454 Seq. ID No. 2987 Seq. ID No. 2988 yes Cyto 1 1455b Seq. ID No. 2991 Seq. ID No. 2992 yes OM 1 1457a Seq. ID No. 2995 Seq. ID No. 2996 yes IM 3 1457b Seq. ID No. 2997 Seq. ID No. 2998 maybe IM 4 1462b Seq. ID No. 3005 Seq. ID No. 3006 yes IM 6 1463a Seq. ID No. 3007 Seq. ID No. 3008 YES IM 2 1463b Seq. ID No. 3009 Seq. ID No. 3010 YES IM 2 14630 Seq. ID No. 3011 Seq. ID No. 3012 YES IM 2 1466a Seq. ID No. 3013 Seq. ID No. 3014 maybe IM 1 1469a Seq. ID No. 3023 Seq. ID No. 3024 NO IM 4 1469b Seq. ID No. 3025 Seq. ID No. 3026 yes IM 5 1469c Seq. ID No. 3027 Seq. ID No. 3028 maybe IM 11 1470a Seq. ID No. 3029 Seq. ID No. 3030 YES IM 5 1470b Seq. ID No. 3031 Seq. ID No. 3032 YES IM 7 1475 Seq. ID No. 3043 Seq. ID No. 3044 yes OM 1 1479c Seq. ID No. 3055 Seq. ID No. 3056 NO Peri 1 1484a Seq. ID No. 3063 Seq. ID No. 3064 maybe IM 4 1487 Seq. ID No. 3071 Seq. ID No. 3072 maybe OM 2 1488a Seq. ID No. 3073 Seq. ID No. 3074 yes IM 1 1488b Seq. ID No. 3075 Seq. ID No. 3076 yes IM 2 1488c Seq. ID No. 3077 Seq. ID No. 3078 maybe IM 3 1507a Seq. ID No. 3119 Seq. ID No. 3120 NO IM 2 1507b Seq. ID No. 3121 Seq. ID No. 3122 NO IM 2 1507c Seq. ID No. 3123 Seq. ID No. 3124 maybe IM 2 1517a Seq. ID No. 3145 Seq. ID No. 3146 NO Peri 1 1520 Seq. ID No. 3155 Seq. ID No. 3156 yes Peri 1 1522 Seq. ID No. 3157 Seq. ID No. 3158 NO Peri 1 1530a Seq. ID No. 3163 Seq. ID No. 3164 yes OM 1 1530b Seq. ID No. 3165 Seq. ID No. 3166 yes IM 1 1535a Seq. ID No. 3173 Seq. ID No. 3174 maybe Cyto 1 1543 Seq. ID No. 3183 Seq. ID No. 3184 yes OM 1 1552 Seq. ID No. 3193 Seq. ID No. 3194 maybe IM 2 1554b Seq. ID No. 3201 Seq. ID No. 3202 maybe IM 2 1557a Seq. ID No. 3213 Seq. ID No. 3214 yes IM 4 1557b Seq. ID No. 3215 Seq. ID No. 3216 yes IM 5 1557c Seq. ID No. 3217 Seq. ID No. 3218 maybe IM 6 1559a Seq. ID No. 3219 Seq. ID No. 3220 YES IM 4 1572a Seq. ID No. 3241 Seq. ID No. 3242 maybe IM 2 1572b Seq. ID No. 3243 Seq. ID No. 3244 NO IM 8 1572c Seq. ID No. 3245 Seq. ID No. 3246 yes IM 10 1572e Seq. ID No. 3249 Seq. ID No. 3250 NO IM 12 1577a Seq. ID No. 3255 Seq. ID No. 3256 maybe IM 4 1577b Seq. ID No. 3257 Seq. ID No. 3258 maybe IM 4 1580a Seq. ID No. 3261 Seq. ID No. 3262 yes IM 1 1580b Seq. ID No. 3263 Seq. ID No. 3264 yes IM 1 1582b Seq. ID No. 3269 Seq. ID No. 3270 yes IM 1 1585a Seq. ID No. 3275 Seq. ID No. 3276 yes IM 1 1585b Seq. ID No. 3277 Seq. ID No. 3278 yes IM 1 1594a Seq. ID No. 3297 Seq. ID No. 3298 YES IM 1 1606a Seq. ID No. 3317 Seq. ID No. 3318 yes IM 1 1607b Seq. ID No. 3323 Seq. ID No. 3324 maybe IM 6 1608 Seq. ID No. 3325 Seq. ID No. 3326 yes Cyto 1 1612 Seq. ID No. 3331 Seq. ID No. 3332 YES IM 3 1616b Seq. ID No. 3335 Seq. ID No. 3336 YES IM 4 1619 Seq. ID No. 3337 Seq. ID No. 3338 yes OM 1 1621 Seq. ID No. 3339 Seq. ID No. 3340 maybe IM 1 1624 Seq. ID No. 3349 Seq. ID No. 3350 YES Peri 1 1625a Seq. ID No. 3351 Seq. ID No. 3352 yes IM 4 1625b Seq. ID No. 3353 Seq. ID No. 3354 YES IM 8 1625c Seq. ID No. 3355 Seq. ID No. 3356 YES IM 8 1626a Seq. ID No. 3357 Seq. ID No. 3358 maybe IM 4 1626b Seq. ID No. 3359 Seq. ID No. 3360 maybe IM 9 1634b Seq. ID No. 3375 Seq. ID No. 3376 maybe OM 0 1634c Seq. ID No. 3377 Seq. ID No. 3378 YES IM 1 1646a Seq. ID No. 3389 Seq. ID No. 3390 yes IM 2 1646b Seq. ID No. 3391 Seq. ID No. 3392 YES IM 6 1646d Seq. ID No. 3395 Seq. ID No. 3396 maybe IM 13 1649a Seq. ID No. 3405 Seq. ID No. 3406 yes Peri 2 1654 Seq. ID No. 3415 Seq. ID No. 3416 maybe Peri 0 1659a Seq. ID No. 3421 Seq. ID No. 3422 yes OM 1 1659c Seq. ID No. 3425 Seq. ID No. 3426 YES IM 10 1660b Seq. ID No. 3427 Seq. ID No. 3428 maybe IM 4 1663 Seq. ID No. 3433 Seq. ID No. 3434 maybe Cyto 0 1669 Seq. ID No. 3441 Seq. ID No. 3442 maybe Cyto 1 1673a Seq. ID No. 3449 Seq. ID No. 3450 YES IM 2 1673b Seq. ID No. 3451 Seq. ID No. 3452 yes IM 8 1673c Seq. ID No. 3453 Seq. ID No. 3454 yes IM 10 1673d Seq. ID No. 3455 Seq. ID No. 3456 yes IM 12 1673e Seq. ID No. 3457 Seq. ID No. 3458 maybe IM 13 1675a Seq. ID No. 3463 Seq. ID No. 3464 maybe IM 1 1683a Seq. ID No. 3481 Seq. ID No. 3482 maybe IM 4 1688a Seq. ID No. 3491 Seq. ID No. 3492 yes IM 3 1688b Seq. ID No. 3493 Seq. ID No. 3494 YES IM 10 1690a Seq. ID No. 3503 Seq. ID No. 3504 yes IM 1 1690b Seq. ID No. 3505 Seq. ID No. 3506 yes IM 2 1694c Seq. ID No. 3517 Seq. ID No. 3518 yes IM 1 1694d Seq. ID No. 3519 Seq. ID No. 3520 yes IM 1 1699a Seq. ID No. 3527 Seq. ID No. 3528 maybe IM 7 1700a Seq. ID No. 3531 Seq. ID No. 3532 maybe IM 4 1703b Seq. ID No. 3539 Seq. ID No. 3540 NO Cyto 0 1710b Seq. ID No. 3561 Seq. ID No. 3562 NO Cyto 1718b Seq. ID No. 3573 Seq. ID No. 3574 YES Cyto 1724 Seq. ID No. 3581 Seq. ID No. 3582 maybe IM 2 1731 Seq. ID No. 3587 Seq. ID No. 3588 NO IM 2 1735a Seq. ID No. 3593 Seq. ID No. 3594 yes OM 1 1735b Seq. ID No. 3595 Seq. ID No. 3596 maybe OM 3 1743 Seq. ID No. 3611 Seq. ID No. 3612 YES IM 1 1745 Seq. ID No. 3617 Seq. ID No. 3618 yes Peri 0 1747 Seq. ID No. 3619 Seq. ID No. 3620 YES IM 2 1749a Seq. ID No. 3621 Seq. ID No. 3622 yes IM 3 1750a Seq. ID No. 3625 Seq. ID No. 3626 maybe IM 2 1752b Seq. ID No. 3629 Seq. ID No. 3630 yes Peri 1 1756b Seq. ID No. 3635 Seq. ID No. 3636 maybe OM 1 1778a Seq. ID No. 3677 Seq. ID No. 3678 maybe IM 1 1778b Seq. ID No. 3679 Seq. ID No. 3680 maybe Cyto 1 1784b Seq. ID No. 3689 Seq. ID No. 3690 YES IM 1 1794a Seq. ID No. 3717 Seq. ID No. 3718 maybe OM 1 1798a Seq. ID No. 3723 Seq. ID No. 3724 yes IM 2 1798c Seq. ID No. 3727 Seq. ID No. 3728 maybe IM 4 1805 Seq. ID No. 3741 Seq. ID No. 3742 yes IM 3 1806b Seq. ID No. 3745 Seq. ID No. 3746 yes IM 5 1808a Seq. ID No. 3753 Seq. ID No. 3754 YES IM 3 1808b Seq. ID No. 3755 Seq. ID No. 3756 YES IM 5 1808c Seq. ID No. 3757 Seq. ID No. 3758 maybe IM 9 1809a Seq. ID No. 3761 Seq. ID No. 3762 maybe IM 5 1809b Seq. ID No. 3763 Seq. ID No. 3764 yes IM 7 1809c Seq. ID No. 3765 Seq. ID No. 3766 YES IM 8 1812a Seq. ID No. 3781 Seq. ID No. 3782 YES IM 1 1812b Seq. ID No. 3783 Seq. ID No. 3784 YES IM 2 1816a Seq. ID No. 3793 Seq. ID No. 3794 yes Peri 1 1817a Seq. ID No. 3799 Seq. ID No. 3800 maybe IM 3 1822 Seq. ID No. 3807 Seq. ID No. 3808 maybe Cyto 1 1825 Seq. ID No. 3813 Seq. ID No. 3814 yes IM 2 1826a Seq. ID No. 3815 Seq. ID No. 3816 NO Cyto 0 1826b Seq. ID No. 3817 Seq. ID No. 3818 NO Cyto 0 1838a Seq. ID No. 3837 Seq. ID No. 3838 yes IM 3 1838b Seq. ID No. 3839 Seq. ID No. 3840 yes IM 4 1842a Seq. ID No. 3849 Seq. ID No. 3850 maybe IM 2 1842b Seq. ID No. 3851 Seq. ID No. 3852 YES IM 6 1842c Seq. ID No. 3853 Seq. ID No. 3854 maybe IM 8 1845a Seq. ID No. 3859 Seq. ID No. 3860 maybe IM 3 1845b Seq. ID No. 3861 Seq. ID No. 3862 yes IM 8 1845c Seq. ID No. 3863 Seq. ID No. 3864 maybe IM 10 1848a Seq. ID No. 3865 Seq. ID No. 3866 yes IM 7 1854a Seq. ID No. 3879 Seq. ID No. 3880 NO IM 3 1857b Seq. ID No. 3889 Seq. ID No. 3890 yes IM 5 1857c Seq. ID No. 3891 Seq. ID No. 3892 yes IM 6 1858 Seq. ID No. 3895 Seq. ID No. 3896 yes Cyto 0 1862a Seq. ID No. 3903 Seq. ID No. 3904 YES IM 1 1868 Seq. ID No. 3915 Seq. ID No. 3916 yes IM 1 1873b Seq. ID No. 3923 Seq. ID No. 3924 yes Peri 1 1873c Seq. ID No. 3925 Seq. ID No. 3926 yes Peri 1 1894c Seq. ID No. 3959 Seq. ID No. 3960 maybe IM 1 1896a Seq. ID No. 3963 Seq. ID No. 3964 maybe Peri 1 1898a Seq. ID No. 3973 Seq. ID No. 3974 maybe IM 2 1898b Seq. ID No. 3975 Seq. ID No. 3976 yes IM 4 1916 Seq. ID No. 3993 Seq. ID No. 3994 maybe IM 1 1917a Seq. ID No. 3995 Seq. ID No. 3996 yes IM 0 1917b Seq. ID No. 3997 Seq. ID No. 3998 yes IM 0 1919a Seq. ID No. 4005 Seq. ID No. 4006 YES Peri 1 1919b Seq. ID No. 4007 Seq. ID No. 4008 YES IM 1 1919c Seq. ID No. 4009 Seq. ID No. 4010 yes IM 1 1931a Seq. ID No. 4025 Seq. ID No. 4026 NO IM 2 1931b Seq. ID No. 4027 Seq. ID No. 4028 YES IM 3 1936 Seq. ID No. 4039 Seq. ID No. 4040 yes IM 6 1937a Seq. ID No. 4041 Seq. ID No. 4042 yes IM 2 1937b Seq. ID No. 4043 Seq. ID No. 4044 maybe IM 3 1937c Seq. ID No. 4045 Seq. ID No. 4046 maybe IM 4 1937d Seq. ID No. 4047 Seq. ID No. 4048 maybe IM 7 1937e Seq. ID No. 4049 Seq. ID No. 4050 maybe IM 7 1941b Seq. ID No. 4061 Seq. ID No. 4062 yes IM 4 1946a Seq. ID No. 4071 Seq. ID No. 4072 NO IM 4 1946b Seq. ID No. 4073 Seq. ID No. 4074 YES IM 8 1950 Seq. ID No. 4079 Seq. ID No. 4080 yes OM 1 1951a Seq. ID No. 4081 Seq. ID No. 4082 yes IM 3 1951b Seq. ID No. 4083 Seq. ID No. 4084 maybe IM 4 1958a Seq. ID No. 4101 Seq. ID No. 4102 maybe IM 4 1958b Seq. ID No. 4103 Seq. ID No. 4104 maybe IM 7 1960c Seq. ID No. 4111 Seq. ID No. 4112 yes IM 1 1970b Seq. ID No. 4133 Seq. ID No. 4134 maybe OM 1 1972 Seq. ID No. 4135 Seq. ID No. 4136 yes Cyto 1 1973 Seq. ID No. 4137 Seq. ID No. 4138 YES OM 1 1976 Seq. ID No. 4139 Seq. ID No. 4140 yes IM 1 1977a Seq. ID No. 4141 Seq. ID No. 4142 YES OM 1 1977b Seq. ID No. 4143 Seq. ID No. 4144 YES OM 1 1977c Seq. ID No. 4145 Seq. ID No. 4146 YES OM 1 1980a Seq. ID No. 4151 Seq. ID No. 4152 NO Cyto 1 1980b Seq. ID No. 4153 Seq. ID No. 4154 maybe Cyto 1 1991 Seq. ID No. 4181 Seq. ID No. 4182 yes Cyto 1 2016a Seq. ID No. 4221 Seq. ID No. 4222 yes IM 2 2016b Seq. ID No. 4223 Seq. ID No. 4224 maybe IM 4 2016c Seq. ID No. 4225 Seq. ID No. 4226 YES IM 7 2016d Seq. ID No. 4227 Seq. ID No. 4228 maybe IM 11 2016f Seq. ID No. 4231 Seq. ID No. 4232 maybe IM 13 2016g Seq. ID No. 4233 Seq. ID No. 4234 NO IM 13 2023a Seq. ID No. 4241 Seq. ID No. 4242 maybe IM 4 2024b Seq. ID No. 4247 Seq. ID No. 4248 yes IM 2 2025 Seq. ID No. 4253 Seq. ID No. 4254 yes OM 1 2030a Seq. ID No. 4257 Seq. ID No. 4258 yes IM 4 2030b Seq. ID No. 4259 Seq. ID No. 4260 yes IM 5 2030c Seq. ID No. 4261 Seq. ID No. 4262 yes IM 5 2030d Seq. ID No. 4263 Seq. ID No. 4264 yes IM 5 2032c Seq. ID No. 4265 Seq. ID No. 4266 maybe Cyto 2035b Seq. ID No. 4269 Seq. ID No. 4270 yes Cyto 0 2038a Seq. ID No. 4275 Seq. ID No. 4276 NO Cyto 0 2045a Seq. ID No. 4285 Seq. ID No. 4286 maybe Cyto 1 2045b Seq. ID No. 4287 Seq. ID No. 4288 maybe Cyto 1 2049c Seq. ID No. 4297 Seq. ID No. 4298 maybe Cyto 2056 Seq. ID No. 4307 Seq. ID No. 4308 maybe Peri 1 2059a Seq. ID No. 4311 Seq. ID No. 4312 yes IM 2 2059b Seq. ID No. 4313 Seq. ID No. 4314 maybe IM 4 2074b Seq. ID No. 4343 Seq. ID No. 4344 YES OM 1 2092 Seq. ID No. 4379 Seq. ID No. 4380 yes IM 2 2096a Seq. ID No. 4385 Seq. ID No. 4386 YES IM 4 2096c Seq. ID No. 4389 Seq. ID No. 4390 yes IM 10 2096d Seq. ID No. 4391 Seq. ID No. 4392 yes IM 10 2101 Seq. ID No. 4399 Seq. ID No. 4400 YES Peri 1 2105 Seq. ID No. 4403 Seq. ID No. 4404 maybe Cyto 1 2120a Seq. ID No. 4437 Seq. ID No. 4438 NO IM 1 2120b Seq. ID No. 4439 Seq. ID No. 4440 NO IM 1 2122b Seq. ID No. 4441 Seq. ID No. 4442 maybe IM 4 2140a Seq. ID No. 4469 Seq. ID No. 4470 YES IM 4 2142a Seq. ID No. 4473 Seq. ID No. 4474 yes IM 1 2146 Seq. ID No. 4481 Seq. ID No. 4482 yes OM 1 2147a Seq. ID No. 4483 Seq. ID No. 4484 YES IM 2 2147b Seq. ID No. 4485 Seq. ID No. 4486 maybe IM 5 2150a Seq. ID No. 4493 Seq. ID No. 4494 YES IM 1 2150b Seq. ID No. 4495 Seq. ID No. 4496 YES IM 2 2150c Seq. ID No. 4497 Seq. ID No. 4498 maybe IM 2 2159a Seq. ID No. 4513 Seq. ID No. 4514 maybe IM 2 2159b Seq. ID No. 4515 Seq. ID No. 4516 maybe IM 2 2161b Seq. ID No. 4527 Seq. ID No. 4528 maybe Cyto 1 2161c Seq. ID No. 4529 Seq. ID No. 4530 maybe Cyto 1 2165 Seq. ID No. 4533 Seq. ID No. 4534 YES IM 1 2190a Seq. ID No. 4587 Seq. ID No. 4588 maybe IM 1 2190b Seq. ID No. 4589 Seq. ID No. 4590 NO Peri 1 2219a Seq. ID No. 4639 Seq. ID No. 4640 yes IM 1 2219b Seq. ID No. 4641 Seq. ID No. 4642 maybe IM 4 2219c Seq. ID No. 4643 Seq. ID No. 4644 maybe IM 4 2225 Seq. ID No. 4659 Seq. ID No. 4660 yes OM 0 2236a Seq. ID No. 4681 Seq. ID No. 4682 yes IM 2 2239b Seq. ID No. 4687 Seq. ID No. 4688 maybe Cyto 0 2243a Seq. ID No. 4695 Seq. ID No. 4696 maybe IM 2 2249 Seq. ID No. 4705 Seq. ID No. 4706 yes OM 1 2253a Seq. ID No. 4707 Seq. ID No. 4708 NO IM 2 2253b Seq. ID No. 4709 Seq. ID No. 4710 YES IM 4 2253c Seq. ID No. 4711 Seq. ID No. 4712 YES IM 5 2255a Seq. ID No. 4715 Seq. ID No. 4716 NO IM 3 2255b Seq. ID No. 4717 Seq. ID No. 4718 yes IM 6 2264b Seq. ID No. 4737 Seq. ID No. 4738 yes IM 1 2276a Seq. ID No. 4759 Seq. ID No. 4760 NO IM 1 2300 Seq. ID No. 4813 Seq. ID No. 4814 yes IM 4 2308 Seq. ID No. 4827 Seq. ID No. 4828 YES OM 1 2320 Seq. ID No. 4853 Seq. ID No. 4854 maybe IM 1 2324 Seq. ID No. 4863 Seq. ID No. 4864 maybe IM 2 2329a Seq. ID No. 4869 Seq. ID No. 4870 yes IM 1 2329b Seq. ID No. 4871 Seq. ID No. 4872 YES IM 3 2329c Seq. ID No. 4873 Seq. ID No. 4874 YES IM 6 2329d Seq. ID No. 4875 Seq. ID No. 4876 yes IM 7 2357 Seq. ID No. 4919 Seq. ID No. 4920 yes IM 2 2358 Seq. ID No. 4921 Seq. ID No. 4922 YES IM 2 2360 Seq. ID No. 4923 Seq. ID No. 4924 NO Cyto 1 2363a Seq. ID No. 4929 Seq. ID No. 4930 yes IM 1 2363b Seq. ID No. 4931 Seq. ID No. 4932 yes IM 1 2371a Seq. ID No. 4949 Seq. ID No. 4950 NO IM 1 2372 Seq. ID No. 4951 Seq. ID No. 4952 maybe Peri 1 2382c Seq. ID No. 4975 Seq. ID No. 4976 maybe Cyto 2390 Seq. ID No. 4987 Seq. ID No. 4988 NO Peri 1 2397 Seq. ID No. 4999 Seq. ID No. 5000 maybe Peri 0 2402b Seq. ID No. 5013 Seq. ID No. 5014 maybe IM 1 2412 Seq. ID No. 5031 Seq. ID No. 5032 yes IM 2 2423a Seq. ID No. 5061 Seq. ID No. 5062 yes IM 5 2423b Seq. ID No. 5063 Seq. ID No. 5064 yes IM 5 2424c Seq. ID No. 5069 Seq. ID No. 5070 yes IM 1 2434 Seq. ID No. 5085 Seq. ID No. 5086 maybe Cyto 1 2445 Seq. ID No. 5103 Seq. ID No. 5104 yes IM 1 2453 Seq. ID No. 5115 Seq. ID No. 5116 YES OM 0 2456c Seq. ID No. 5123 Seq. ID No. 5124 yes IM 8 2456d Seq. ID No. 5125 Seq. ID No. 5126 maybe IM 9 2458a Seq. ID No. 5129 Seq. ID No. 5130 maybe IM 5 2458b Seq. ID No. 5131 Seq. ID No. 5132 yes IM 6 2458c Seq. ID No. 5133 Seq. ID No. 5134 yes IM 7 2458d Seq. ID No. 5135 Seq. ID No. 5136 yes IM 7 2458e Seq. ID No. 5137 Seq. ID No. 5138 yes IM 8 2458f Seq. ID No. 5139 Seq. ID No. 5140 yes IM 9 2458g Seq. ID No. 5141 Seq. ID No. 5142 yes IM 9 2468a Seq. ID No. 5159 Seq. ID No. 5160 yes IM 1 2469b Seq. ID No. 5165 Seq. ID No. 5166 yes IM 2 2474b Seq. ID No. 5175 Seq. ID No. 5176 yes IM 3 2484a Seq. ID No. 5197 Seq. ID No. 5198 maybe Peri 1 2484b Seq. ID No. 5199 Seq. ID No. 5200 maybe Peri 1 2490 Seq. ID No. 5205 Seq. ID No. 5206 yes IM 1 2492a Seq. ID No. 5207 Seq. ID No. 5208 yes IM 1 2495a Seq. ID No. 5213 Seq. ID No. 5214 maybe IM 9 2497b Seq. ID No. 5219 Seq. ID No. 5220 yes Peri 2 2500a Seq. ID No. 5223 Seq. ID No. 5224 yes OM 1 2518a Seq. ID No. 5267 Seq. ID No. 5268 YES Cyto 1 2520a Seq. ID No. 5273 Seq. ID No. 5274 NO Cyto 0 2520b Seq. ID No. 5275 Seq. ID No. 5276 NO Cyto 0 2520c Seq. ID No. 5277 Seq. ID No. 5278 NO Cyto 0 2520d Seq. ID No. 5279 Seq. ID No. 5280 NO Cyto 0 2521 Seq. ID No. 5281 Seq. ID No. 5282 maybe IM 3 2525a Seq. ID No. 5285 Seq. ID No. 5286 yes IM 1 2546 Seq. ID No. 5327 Seq. ID No. 5328 NO Cyto 1 2547b Seq. ID No. 5329 Seq. ID No. 5330 yes IM 1 2547c Seq. ID No. 5331 Seq. ID No. 5332 yes IM 1 2550c Seq. ID No. 5341 Seq. ID No. 5342 YES IM 2564b Seq. ID No. 5377 Seq. ID No. 5378 yes OM 1 2564c Seq. ID No. 5379 Seq. ID No. 5380 yes OM 1 2567a Seq. ID No. 5385 Seq. ID No. 5386 yes IM 4 2567b Seq. ID No. 5387 Seq. ID No. 5388 YES IM 5 2582a Seq. ID No. 5405 Seq. ID No. 5406 yes IM 4 2587a Seq. ID No. 5413 Seq. ID No. 5414 NO Peri 2 2587b Seq. ID No. 5415 Seq. ID No. 5416 maybe IM 5 2596 Seq. ID No. 5433 Seq. ID No. 5434 NO IM 1 2610 Seq. ID No. 5453 Seq. ID No. 5454 yes IM 1 2616a Seq. ID No. 5459 Seq. ID No. 5460 yes IM 2 2616b Seq. ID No. 5461 Seq. ID No. 5462 yes IM 3 2616c Seq. ID No. 5463 Seq. ID No. 5464 yes IM 4 2616d Seq. ID No. 5465 Seq. ID No. 5466 YES IM 5 2623b Seq. ID No. 5491 Seq. ID No. 5492 maybe OM 1 2625a Seq. ID No. 5497 Seq. ID No. 5498 YES Peri 1 2628 Seq. ID No. 5509 Seq. ID No. 5510 yes IM 1 2629b Seq. ID No. 5513 Seq. ID No. 5514 YES OM 1 2631 Seq. ID No. 5515 Seq. ID No. 5516 NO Cyto 1 2632 Seq. ID No. 5517 Seq. ID No. 5518 NO Cyto 1 2633d Seq. ID No. 5525 Seq. ID No. 5526 maybe OM 1 2637a Seq. ID No. 5529 Seq. ID No. 5530 yes OM 1 2637b Seq. ID No. 5531 Seq. ID No. 5532 yes IM 1 2642 Seq. ID No. 5533 Seq. ID No. 5534 NO IM 2 2648a Seq. ID No. 5543 Seq. ID No. 5544 YES IM 0 2648b Seq. ID No. 5545 Seq. ID No. 5546 YES IM 0 2660 Seq. ID No. 5569 Seq. ID No. 5570 yes Peri 1 2669a Seq. ID No. 5587 Seq. ID No. 5588 YES Peri 2 2669b Seq. ID No. 5589 Seq. ID No. 5590 YES IM 2 2669c Seq. ID No. 5591 Seq. ID No. 5592 YES IM 2 2672 Seq. ID No. 5593 Seq. ID No. 5594 NO IM 3 2673 Seq. ID No. 5595 Seq. ID No. 5596 maybe IM 2 2674a Seq. ID No. 5597 Seq. ID No. 5598 maybe IM 4 2679a Seq. ID No. 5609 Seq. ID No. 5610 NO IM 4 2679b Seq. ID No. 5611 Seq. ID No. 5612 YES IM 5 2680c Seq. ID No. 5621 Seq. ID No. 5622 YES IM 1 2683a Seq. ID No. 5623 Seq. ID No. 5624 yes IM 1 2683b Seq. ID No. 5625 Seq. ID No. 5626 yes IM 1 2688a Seq. ID No. 5633 Seq. ID No. 5634 maybe IM 2 2688c Seq. ID No. 5637 Seq. ID No. 5638 maybe IM 4 2689a Seq. ID No. 5639 Seq. ID No. 5640 maybe Peri 0 2689b Seq. ID No. 5641 Seq. ID No. 5642 YES Peri 0 2690a Seq. ID No. 5643 Seq. ID No. 5644 yes Peri 1 2692b Seq. ID No. 5649 Seq. ID No. 5650 maybe IM 1 2696a Seq. ID No. 5659 Seq. ID No. 5660 yes IM 8 2710c Seq. ID No. 5667 Seq. ID No. 5668 maybe Cyto 2718a Seq. ID No. 5681 Seq. ID No. 5682 YES IM 3 2718b Seq. ID No. 5683 Seq. ID No. 5684 yes IM 3 2718c Seq. ID No. 5685 Seq. ID No. 5686 yes IM 4 2719a Seq. ID No. 5687 Seq. ID No. 5688 maybe Cyto 0 2719b Seq. ID No. 5689 Seq. ID No. 5690 maybe Cyto 0 2723 Seq. ID No. 5699 Seq. ID No. 5700 maybe IM 4 2725a Seq. ID No. 5703 Seq. ID No. 5704 maybe Peri 2 2725b Seq. ID No. 5705 Seq. ID No. 5706 maybe Cyto 2 2728a Seq. ID No. 5709 Seq. ID No. 5710 yes IM 1 2728b Seq. ID No. 5711 Seq. ID No. 5712 yes IM 1 2734a Seq. ID No. 5719 Seq. ID No. 5720 YES IM 3 2738a Seq. ID No. 5729 Seq. ID No. 5730 maybe IM 10 2738c Seq. ID No. 5733 Seq. ID No. 5734 yes IM 12 2738d Seq. ID No. 5735 Seq. ID No. 5736 maybe IM 12 2742b Seq. ID No. 5739 Seq. ID No. 5740 yes Peri 2749a Seq. ID No. 5763 Seq. ID No. 5764 NO IM 3 2749b Seq. ID No. 5765 Seq. ID No. 5766 yes IM 4 2749c Seq. ID No. 5767 Seq. ID No. 5768 NO IM 8 2749e Seq. ID No. 5771 Seq. ID No. 5772 YES IM 10 2757b Seq. ID No. 5783 Seq. ID No. 5784 YES IM 5 2758a Seq. ID No. 5785 Seq. ID No. 5786 NO Cyto 0 2758d Seq. ID No. 5791 Seq. ID No. 5792 maybe Cyto 1 2760a Seq. ID No. 5797 Seq. ID No. 5798 yes Peri 1 2770 Seq. ID No. 5829 Seq. ID No. 5830 maybe IM 1 2791 Seq. ID No. 5879 Seq. ID No. 5880 maybe IM 1 2794 Seq. ID No. 5883 Seq. ID No. 5884 NO IM 2 2796a Seq. ID No. 5885 Seq. ID No. 5886 maybe IM 2 2799a Seq. ID No. 5889 Seq. ID No. 5890 yes OM 1 2801a Seq. ID No. 5893 Seq. ID No. 5894 yes IM 1 2801b Seq. ID No. 5895 Seq. ID No. 5896 YES IM 2 2805a Seq. ID No. 5899 Seq. ID No. 5900 YES IM 2 2805b Seq. ID No. 5901 Seq. ID No. 5902 YES IM 4 2810a Seq. ID No. 5905 Seq. ID No. 5906 yes IM 3 2810c Seq. ID No. 5909 Seq. ID No. 5910 yes IM 4 2818a Seq. ID No. 5921 Seq. ID No. 5922 maybe IM 2 2818b Seq. ID No. 5923 Seq. ID No. 5924 yes IM 5 2818d Seq. ID No. 5927 Seq. ID No. 5928 YES IM 6 2818e Seq. ID No. 5929 Seq. ID No. 5930 YES IM 6 2822a Seq. ID No. 5939 Seq. ID No. 5940 YES IM 3 2869a Seq. ID No. 6023 Seq. ID No. 6024 maybe OM 1 2869b Seq. ID No. 6025 Seq. ID No. 6026 yes OM 1 2869c Seq. ID No. 6027 Seq. ID No. 6028 yes IM 1 2881 Seq. ID No. 6043 Seq. ID No. 6044 yes IM 1 2883a Seq. ID No. 6047 Seq. ID No. 6048 yes IM 6 2883d Seq. ID No. 6053 Seq. ID No. 6054 yes IM 8 2887a Seq. ID No. 6059 Seq. ID No. 6060 yes Peri 1 2888 Seq. ID No. 6063 Seq. ID No. 6064 maybe Cyto 1 2891a Seq. ID No. 6067 Seq. ID No. 6068 NO Peri 1 2900a Seq. ID No. 6087 Seq. ID No. 6088 YES Peri 1 2900b Seq. ID No. 6089 Seq. ID No. 6090 YES Peri 1 2901a Seq. ID No. 6091 Seq. ID No. 6092 YES IM 1 2902 Seq. ID No. 6095 Seq. ID No. 6096 YES IM 0 2906 Seq. ID No. 6103 Seq. ID No. 6104 YES IM 2 2909b Seq. ID No. 6107 Seq. ID No. 6108 maybe Cyto 1 2909c Seq. ID No. 6109 Seq. ID No. 6110 yes IM 4 2909d Seq. ID No. 6111 Seq. ID No. 6112 yes IM 4 2913a Seq. ID No. 6115 Seq. ID No. 6116 yes IM 2 2913b Seq. ID No. 6117 Seq. ID No. 6118 yes IM 2 2922b Seq. ID No. 6135 Seq. ID No. 6136 yes Cyto 0 2923a Seq. ID No. 6137 Seq. ID No. 6138 yes Cyto 2929b Seq. ID No. 6159 Seq. ID No. 6160 maybe Cyto 2931a Seq. ID No. 6161 Seq. ID No. 6162 yes IM 5 2931b Seq. ID No. 6163 Seq. ID No. 6164 NO IM 6 2931c Seq. ID No. 6165 Seq. ID No. 6166 yes IM 13 2933b Seq. ID No. 6169 Seq. ID No. 6170 YES IM 1 2941a Seq. ID No. 6183 Seq. ID No. 6184 yes IM 2 2941b Seq. ID No. 6185 Seq. ID No. 6186 YES IM 5 2941c Seq. ID No. 6187 Seq. ID No. 6188 YES IM 5 2943a Seq. ID No. 6189 Seq. ID No. 6190 yes IM 3 2943b Seq. ID No. 6191 Seq. ID No. 6192 yes IM 5 2944b Seq. ID No. 6197 Seq. ID No. 6198 YES IM 1 2948a Seq. ID No. 6203 Seq. ID No. 6204 YES IM 1 2948b Seq. ID No. 6205 Seq. ID No. 6206 YES IM 5 2948d Seq. ID No. 6209 Seq. ID No. 6210 yes IM 7 2952 Seq. ID No. 6217 Seq. ID No. 6218 yes Cyto 1 2955a Seq. ID No. 6221 Seq. ID No. 6222 YES IM 4 2955b Seq. ID No. 6223 Seq. ID No. 6224 YES IM 4 2955c Seq. ID No. 6225 Seq. ID No. 6226 yes IM 6 2955d Seq. ID No. 6227 Seq. ID No. 6228 maybe IM 7 2955e Seq. ID No. 6229 Seq. ID No. 6230 YES IM 11 2957 Seq. ID No. 6235 Seq. ID No. 6236 yes IM 4 2958a Seq. ID No. 6237 Seq. ID No. 6238 maybe IM 2 2958c Seq. ID No. 6241 Seq. ID No. 6242 maybe IM 2 2959 Seq. ID No. 6243 Seq. ID No. 6244 yes IM 2 2960a Seq. ID No. 6245 Seq. ID No. 6246 maybe IM 2 2962b Seq. ID No. 6249 Seq. ID No. 6250 yes IM 1 2965a Seq. ID No. 6253 Seq. ID No. 6254 yes Cyto 1 2966 Seq. ID No. 6259 Seq. ID No. 6260 yes IM 1 2969 Seq. ID No. 6263 Seq. ID No. 6264 maybe IM 1 2970a Seq. ID No. 6265 Seq. ID No. 6266 yes IM 1 2970b Seq. ID No. 6267 Seq. ID No. 6268 yes IM 1 2974a Seq. ID No. 6273 Seq. ID No. 6274 maybe Peri 2 2974b Seq. ID No. 6275 Seq. ID No. 6276 yes IM 4 2978a Seq. ID No. 6283 Seq. ID No. 6284 yes Peri 1 2978b Seq. ID No. 6285 Seq. ID No. 6286 yes Peri 1 2980a Seq. ID No. 6289 Seq. ID No. 6290 maybe IM 3 2986a Seq. ID No. 6301 Seq. ID No. 6302 maybe IM 6 2986b Seq. ID No. 6303 Seq. ID No. 6304 yes IM 7 2993a Seq. ID No. 6325 Seq. ID No. 6326 yes OM 0 2993b Seq. ID No. 6327 Seq. ID No. 6328 yes OM 0 3016a Seq. ID No. 6363 Seq. ID No. 6364 yes IM 4 3016b Seq. ID No. 6365 Seq. ID No. 6366 yes IM 7 3021 Seq. ID No. 6377 Seq. ID No. 6378 NO Peri 1 3023 Seq. ID No. 6381 Seq. ID No. 6382 maybe IM 1 3024a Seq. ID No. 6383 Seq. ID No. 6384 maybe Peri 1 3037a Seq. ID No. 6415 Seq. ID No. 6416 YES OM 1 3042a Seq. ID No. 6425 Seq. ID No. 6426 yes Cyto 1 3042b Seq. ID No. 6427 Seq. ID No. 6428 yes Cyto 1 3043a Seq. ID No. 6429 Seq. ID No. 6430 yes IM 2 3043b Seq. ID No. 6431 Seq. ID No. 6432 yes IM 2 3064b Seq. ID No. 6473 Seq. ID No. 6474 YES Peri 1 3066 Seq. ID No. 6479 Seq. ID No. 6480 yes Cyto 0 3076 Seq. ID No. 6497 Seq. ID No. 6498 maybe IM 3 3085 Seq. ID No. 6517 Seq. ID No. 6518 maybe Cyto 0 3096a Seq. ID No. 6541 Seq. ID No. 6542 yes IM 1 3096b Seq. ID No. 6543 Seq. ID No. 6544 YES IM 1 3100a Seq. ID No. 6555 Seq. ID No. 6556 maybe Cyto 0 3100b Seq. ID No. 6557 Seq. ID No. 6558 maybe Cyto 0 3107a Seq. ID No. 6571 Seq. ID No. 6572 yes OM 1 3107b Seq. ID No. 6573 Seq. ID No. 6574 yes OM 2 3110a Seq. ID No. 6581 Seq. ID No. 6582 NO IM 1 3119a Seq. ID No. 6593 Seq. ID No. 6594 NO IM 3 3119b Seq. ID No. 6595 Seq. ID No. 6596 YES IM 4 3119c Seq. ID No. 6597 Seq. ID No. 6598 YES IM 4 3119d Seq. ID No. 6599 Seq. ID No. 6600 YES IM 4 3119e Seq. ID No. 6601 Seq. ID No. 6602 YES IM 4 3119f Seq. ID No. 6603 Seq. ID No. 6604 YES IM 4 3140 Seq. ID No. 6631 Seq. ID No. 6632 maybe IM 2 3145b Seq. ID No. 6637 Seq. ID No. 6638 maybe OM 1 3145c Seq. ID No. 6639 Seq. ID No. 6640 yes OM 1 3147b Seq. ID No. 6643 Seq. ID No. 6644 yes IM 0 3147c Seq. ID No. 6645 Seq. ID No. 6646 yes OM 0 3150a Seq. ID No. 6649 Seq. ID No. 6650 NO Cyto 0

Listed in Table 6 are 2388 ORFs that meet the criteria of being a non-secretory protein, based on the HMM SignalP program. Of these ORFs, the PSORT program predicted 756 ORFs to be localized to the cytoplasmic inner membrane (IM); 35 ORFs to be localized to the periplasm (Peri); 10 ORFs to be localized to the outer membrane (OM); and 1586 ORFs localized to the cytoplasm. Shown for all ORFs is the number of transmembrane domains predicted by the TopPred2 software (listed in the MSD column). TABLE 6 SIGNALP: NON-SECRETORY ORF DNA SEQ Protein SEQ Number ID Number ID Number PSORT MSD 1 Seq. ID No. 1 Seq. ID No. 2 Cyto 2 2b Seq. ID No. 5 Seq. ID No. 6 Cyto 3 4c Seq. ID No. 11 Seq. ID No. 12 IM 12 5 Seq. ID No. 13 Seq. ID No. 14 Cyto 0 7 Seq. ID No. 15 Seq. ID No. 16 Cyto 10 Seq. ID No. 17 Seq. ID No. 18 Cyto 16 Seq. ID No. 23 Seq. ID No. 24 IM 0 17 Seq. ID No. 25 Seq. ID No. 26 Cyto 18 Seq. ID No. 27 Seq. ID No. 28 Cyto 1 20 Seq. ID No. 29 Seq. ID No. 30 IM 1 23b Seq. ID No. 35 Seq. ID No. 36 IM 1 24 Seq. ID No. 37 Seq. ID No. 38 IM 1 32 Seq. ID No. 39 Seq. ID No. 40 Cyto 36 Seq. ID No. 41 Seq. ID No. 42 IM 0 37 Seq. ID No. 43 Seq. ID No. 44 Cyto 39b Seq. ID No. 51 Seq. ID No. 52 IM 5 41a Seq. ID No. 55 Seq. ID No. 56 Cyto 41b Seq. ID No. 57 Seq. ID No. 58 Cyto 41c Seq. ID No. 59 Seq. ID No. 60 IM 1 43b Seq. ID No. 61 Seq. ID No. 62 Cyto 43c Seq. ID No. 63 Seq. ID No. 64 Cyto 45 Seq. ID No. 69 Seq. ID No. 70 Cyto 46a Seq. ID No. 71 Seq. ID No. 72 Cyto 46b Seq. ID No. 73 Seq. ID No. 74 Cyto 47 Seq. ID No. 75 Seq. ID No. 76 Cyto 48a Seq. ID No. 77 Seq. ID No. 78 IM 0 48b Seq. ID No. 79 Seq. ID No. 80 IM 0 48c Seq. ID No. 81 Seq. ID No. 82 IM 0 50 Seq. ID No. 83 Seq. ID No. 84 Cyto 0 51c Seq. ID No. 89 Seq. ID No. 90 IM 10 55 Seq. ID No. 91 Seq. ID No. 92 IM 1 56b Seq. ID No. 93 Seq. ID No. 94 Cyto 57a Seq. ID No. 95 Seq. ID No. 96 IM 0 57b Seq. ID No. 97 Seq. ID No. 98 IM 0 58 Seq. ID No. 99 Seq. ID No. 100 Cyto 60a Seq. ID No. 101 Seq. ID No. 102 Cyto 60b Seq. ID No. 103 Seq. ID No. 104 Cyto 62a Seq. ID No. 107 Seq. ID No. 108 Cyto 0 62b Seq. ID No. 109 Seq. ID No. 110 Cyto 0 63a Seq. ID No. 113 Seq. ID No. 114 OM 0 63b Seq. ID No. 115 Seq. ID No. 116 OM 1 65a Seq. ID No. 117 Seq. ID No. 118 Cyto 65b Seq. ID No. 119 Seq. ID No. 120 Cyto 65c Seq. ID No. 121 Seq. ID No. 122 Cyto 67 Seq. ID No. 125 Seq. ID No. 126 Cyto 69 Seq. ID No. 127 Seq. ID No. 128 Cyto 0 71 Seq. ID No. 129 Seq. ID No. 130 Cyto 0 74 Seq. ID No. 135 Seq. ID No. 136 Cyto 77 Seq. ID No. 137 Seq. ID No. 138 Cyto 79 Seq. ID No. 139 Seq. ID No. 140 IM 2 80b Seq. ID No. 143 Seq. ID No. 144 IM 4 80c Seq. ID No. 145 Seq. ID No. 146 IM 5 81a Seq. ID No. 147 Seq. ID No. 148 Cyto 81b Seq. ID No. 149 Seq. ID No. 150 Cyto 83 Seq. ID No. 151 Seq. ID No. 152 IM 2 85a Seq. ID No. 153 Seq. ID No. 154 Cyto 85b Seq. ID No. 155 Seq. ID No. 156 Cyto 85c Seq. ID No. 157 Seq. ID No. 158 Cyto 87c Seq. ID No. 165 Seq. ID No. 166 IM 2 88 Seq. ID No. 167 Seq. ID No. 168 IM 5 89 Seq. ID No. 169 Seq. ID No. 170 IM 2 91b Seq. ID No. 173 Seq. ID No. 174 IM 0 91c Seq. ID No. 175 Seq. ID No. 176 IM 0 91d Seq. ID No. 177 Seq. ID No. 178 IM 0 93a Seq. ID No. 179 Seq. ID No. 180 Cyto 1 93b Seq. ID No. 181 Seq. ID No. 182 Peri 1 93c Seq. ID No. 183 Seq. ID No. 184 Peri 2 94 Seq. ID No. 185 Seq. ID No. 186 IM 2 95b Seq. ID No. 187 Seq. ID No. 188 Cyto 97b Seq. ID No. 189 Seq. ID No. 190 Cyto 101 Seq. ID No. 193 Seq. ID No. 194 IM 1 102 Seq. ID No. 195 Seq. ID No. 196 Cyto 0 104a Seq. ID No. 197 Seq. ID No. 198 Cyto 104b Seq. ID No. 199 Seq. ID No. 200 Cyto 104c Seq. ID No. 201 Seq. ID No. 202 Peri 1 105a Seq. ID No. 203 Seq. ID No. 204 IM 105b Seq. ID No. 205 Seq. ID No. 206 IM 106 Seq. ID No. 207 Seq. ID No. 208 Cyto 0 111b Seq. ID No. 219 Seq. ID No. 220 IM 8 112a Seq. ID No. 221 Seq. ID No. 222 Cyto 0 112b Seq. ID No. 223 Seq. ID No. 224 Cyto 0 115 Seq. ID No. 227 Seq. ID No. 228 Cyto 119a Seq. ID No. 229 Seq. ID No. 230 IM 2 119b Seq. ID No. 231 Seq. ID No. 232 IM 3 121 Seq. ID No. 233 Seq. ID No. 234 Cyto 0 124c Seq. ID No. 239 Seq. ID No. 240 IM 5 125 Seq. ID No. 241 Seq. ID No. 242 Cyto 127a Seq. ID No. 243 Seq. ID No. 244 Cyto 127b Seq. ID No. 245 Seq. ID No. 246 Cyto 127c Seq. ID No. 247 Seq. ID No. 248 IM 129c Seq. ID No. 253 Seq. ID No. 254 IM 10 134 Seq. ID No. 261 Seq. ID No. 262 Cyto 1 135a Seq. ID No. 263 Seq. ID No. 264 Cyto 135b Seq. ID No. 265 Seq. ID No. 266 Cyto 137a Seq. ID No. 267 Seq. ID No. 268 Cyto 137b Seq. ID No. 269 Seq. ID No. 270 Cyto 142 Seq. ID No. 275 Seq. ID No. 276 Cyto 144a Seq. ID No. 279 Seq. ID No. 280 Peri 0 144b Seq. ID No. 281 Seq. ID No. 282 Peri 0 144c Seq. ID No. 283 Seq. ID No. 284 Cyto 0 145d Seq. ID No. 291 Seq. ID No. 292 IM 12 147 Seq. ID No. 293 Seq. ID No. 294 Cyto 151a Seq. ID No. 295 Seq. ID No. 296 IM 1 151b Seq. ID No. 297 Seq. ID No. 298 IM 1 152a Seq. ID No. 299 Seq. ID No. 300 Cyto 0 152b Seq. ID No. 301 Seq. ID No. 302 Cyto 0 153a Seq. ID No. 303 Seq. ID No. 304 Cyto 153b Seq. ID No. 305 Seq. ID No. 306 Cyto 153c Seq. ID No. 307 Seq. ID No. 308 Cyto 154 Seq. ID No. 309 Seq. ID No. 310 Cyto 0 155a Seq. ID No. 311 Seq. ID No. 312 Cyto 155b Seq. ID No. 313 Seq. ID No. 314 Cyto 157a Seq. ID No. 315 Seq. ID No. 316 Cyto 157b Seq. ID No. 317 Seq. ID No. 318 Cyto 158a Seq. ID No. 319 Seq. ID No. 320 Cyto 158b Seq. ID No. 321 Seq. ID No. 322 Cyto 160a Seq. ID No. 323 Seq. ID No. 324 Cyto 160b Seq. ID No. 325 Seq. ID No. 326 Cyto 162c Seq. ID No. 331 Seq. ID No. 332 IM 5 162d Seq. ID No. 333 Seq. ID No. 334 IM 5 162e Seq. ID No. 335 Seq. ID No. 336 IM 5 163 Seq. ID No. 337 Seq. ID No. 338 Cyto 0 164 Seq. ID No. 339 Seq. ID No. 340 Cyto 165a Seq. ID No. 341 Seq. ID No. 342 IM 165b Seq. ID No. 343 Seq. ID No. 344 IM 167 Seq. ID No. 345 Seq. ID No. 346 IM 169 Seq. ID No. 347 Seq. ID No. 348 IM 2 170 Seq. ID No. 349 Seq. ID No. 350 IM 1 171a Seq. ID No. 351 Seq. ID No. 352 Cyto 171b Seq. ID No. 353 Seq. ID No. 354 Cyto 172 Seq. ID No. 355 Seq. ID No. 356 Cyto 175 Seq. ID No. 361 Seq. ID No. 362 Cyto 176 Seq. ID No. 363 Seq. ID No. 364 Cyto 177a Seq. ID No. 365 Seq. ID No. 366 IM 177b Seq. ID No. 367 Seq. ID No. 368 IM 179a Seq. ID No. 369 Seq. ID No. 370 IM 2 179b Seq. ID No. 371 Seq. ID No. 372 IM 2 183a Seq. ID No. 377 Seq. ID No. 378 IM 1 184 Seq. ID No. 379 Seq. ID No. 380 Cyto 185 Seq. ID No. 381 Seq. ID No. 382 Cyto 186 Seq. ID No. 383 Seq. ID No. 384 Cyto 187a Seq. ID No. 385 Seq. ID No. 386 IM 1 187b Seq. ID No. 387 Seq. ID No. 388 IM 1 188 Seq. ID No. 389 Seq. ID No. 390 Cyto 189b Seq. ID No. 391 Seq. ID No. 392 Cyto 192a Seq. ID No. 395 Seq. ID No. 396 Cyto 0 192b Seq. ID No. 397 Seq. ID No. 398 Cyto 0 193 Seq. ID No. 399 Seq. ID No. 400 Cyto 195 Seq. ID No. 405 Seq. ID No. 406 Cyto 196 Seq. ID No. 407 Seq. ID No. 408 Cyto 1 197a Seq. ID No. 409 Seq. ID No. 410 Cyto 197b Seq. ID No. 411 Seq. ID No. 412 Cyto 198a Seq. ID No. 413 Seq. ID No. 414 Peri 198b Seq. ID No. 415 Seq. ID No. 416 Peri 200 Seq. ID No. 417 Seq. ID No. 418 Cyto 201a Seq. ID No. 419 Seq. ID No. 420 IM 2 202 Seq. ID No. 421 Seq. ID No. 422 Cyto 203 Seq. ID No. 423 Seq. ID No. 424 Cyto 204 Seq. ID No. 425 Seq. ID No. 426 Cyto 205 Seq. ID No. 427 Seq. ID No. 428 Cyto 206 Seq. ID No. 429 Seq. ID No. 430 Cyto 207 Seq. ID No. 431 Seq. ID No. 432 IM 0 208a Seq. ID No. 433 Seq. ID No. 434 Cyto 208b Seq. ID No. 435 Seq. ID No. 436 Cyto 210 Seq. ID No. 437 Seq. ID No. 438 Cyto 211 Seq. ID No. 439 Seq. ID No. 440 Cyto 213 Seq. ID No. 441 Seq. ID No. 442 Cyto 215a Seq. ID No. 443 Seq. ID No. 444 Cyto 218 Seq. ID No. 445 Seq. ID No. 446 Cyto 219 Seq. ID No. 447 Seq. ID No. 448 Cyto 0 220a Seq. ID No. 449 Seq. ID No. 450 Cyto 0 220b Seq. ID No. 451 Seq. ID No. 452 Cyto 0 220c Seq. ID No. 453 Seq. ID No. 454 Cyto 0 226a Seq. ID No. 459 Seq. ID No. 460 Cyto 226b Seq. ID No. 461 Seq. ID No. 462 Cyto 227 Seq. ID No. 463 Seq. ID No. 464 Cyto 228a Seq. ID No. 465 Seq. ID No. 466 Cyto 228b Seq. ID No. 467 Seq. ID No. 468 Cyto 228c Seq. ID No. 469 Seq. ID No. 470 Cyto 228d Seq. ID No. 471 Seq. ID No. 472 Cyto 232a Seq. ID No. 473 Seq. ID No. 474 IM 0 232b Seq. ID No. 475 Seq. ID No. 476 IM 0 235b Seq. ID No. 479 Seq. ID No. 480 Cyto 1 236a Seq. ID No. 481 Seq. ID No. 482 Cyto 236b Seq. ID No. 483 Seq. ID No. 484 Cyto 236c Seq. ID No. 485 Seq. ID No. 486 Cyto 245c Seq. ID No. 501 Seq. ID No. 502 IM 10 247 Seq. ID No. 507 Seq. ID No. 508 IM 3 251 Seq. ID No. 517 Seq. ID No. 518 IM 1 253a Seq. ID No. 519 Seq. ID No. 520 IM 253b Seq. ID No. 521 Seq. ID No. 522 Cyto 254 Seq. ID No. 523 Seq. ID No. 524 IM 1 255c Seq. ID No. 529 Seq. ID No. 530 IM 12 255d Seq. ID No. 531 Seq. ID No. 532 IM 12 258 Seq. ID No. 533 Seq. ID No. 534 Cyto 259a Seq. ID No. 535 Seq. ID No. 536 Cyto 259b Seq. ID No. 537 Seq. ID No. 538 Cyto 259c Seq. ID No. 539 Seq. ID No. 540 Cyto 260 Seq. ID No. 541 Seq. ID No. 542 Cyto 262 Seq. ID No. 543 Seq. ID No. 544 Cyto 265 Seq. ID No. 551 Seq. ID No. 552 Cyto 267b Seq. ID No. 553 Seq. ID No. 554 Cyto 0 267c Seq. ID No. 555 Seq. ID No. 556 Cyto 0 269a Seq. ID No. 559 Seq. ID No. 560 Cyto 269b Seq. ID No. 561 Seq. ID No. 562 IM 0 271a Seq. ID No. 563 Seq. ID No. 564 Cyto 271b Seq. ID No. 565 Seq. ID No. 566 Cyto 277a Seq. ID No. 571 Seq. ID No. 572 Cyto 277b Seq. ID No. 573 Seq. ID No. 574 IM 280a Seq. ID No. 581 Seq. ID No. 582 Cyto 1 280b Seq. ID No. 583 Seq. ID No. 584 Cyto 1 280c Seq. ID No. 585 Seq. ID No. 586 Cyto 1 280d Seq. ID No. 587 Seq. ID No. 588 Cyto 1 282 Seq. ID No. 589 Seq. ID No. 590 Cyto 284a Seq. ID No. 595 Seq. ID No. 596 IM 5 284b Seq. ID No. 597 Seq. ID No. 598 IM 5 286a Seq. ID No. 601 Seq. ID No. 602 Cyto 286b Seq. ID No. 603 Seq. ID No. 604 Cyto 287 Seq. ID No. 605 Seq. ID No. 606 Cyto 290a Seq. ID No. 607 Seq. ID No. 608 Cyto 290b Seq. ID No. 609 Seq. ID No. 610 IM 293 Seq. ID No. 611 Seq. ID No. 612 Cyto 294 Seq. ID No. 613 Seq. ID No. 614 Cyto 0 296 Seq. ID No. 615 Seq. ID No. 616 Cyto 0 300b Seq. ID No. 619 Seq. ID No. 620 IM 0 301a Seq. ID No. 621 Seq. ID No. 622 Cyto 1 301b Seq. ID No. 623 Seq. ID No. 624 Cyto 1 304a Seq. ID No. 625 Seq. ID No. 626 Cyto 1 304b Seq. ID No. 627 Seq. ID No. 628 Cyto 1 307 Seq. ID No. 629 Seq. ID No. 630 Cyto 308 Seq. ID No. 631 Seq. ID No. 632 Cyto 0 309 Seq. ID No. 633 Seq. ID No. 634 IM 0 310 Seq. ID No. 635 Seq. ID No. 636 Cyto 0 315 Seq. ID No. 649 Seq. ID No. 650 Cyto 316a Seq. ID No. 651 Seq. ID No. 652 IM 3 318d Seq. ID No. 663 Seq. ID No. 664 IM 2 318e Seq. ID No. 665 Seq. ID No. 666 IM 2 323a Seq. ID No. 671 Seq. ID No. 672 Cyto 323b Seq. ID No. 673 Seq. ID No. 674 Cyto 327c Seq. ID No. 681 Seq. ID No. 682 IM 5 329 Seq. ID No. 683 Seq. ID No. 684 Cyto 330a Seq. ID No. 685 Seq. ID No. 686 Cyto 0 330b Seq. ID No. 687 Seq. ID No. 688 Cyto 0 330c Seq. ID No. 689 Seq. ID No. 690 Cyto 0 331 Seq. ID No. 691 Seq. ID No. 692 Cyto 332 Seq. ID No. 693 Seq. ID No. 694 Cyto 333 Seq. ID No. 695 Seq. ID No. 696 Cyto 1 334 Seq. ID No. 697 Seq. ID No. 698 Cyto 335a Seq. ID No. 699 Seq. ID No. 700 IM 5 335b Seq. ID No. 701 Seq. ID No. 702 IM 5 337 Seq. ID No. 703 Seq. ID No. 704 Cyto 338a Seq. ID No. 705 Seq. ID No. 706 Cyto 338b Seq. ID No. 707 Seq. ID No. 708 Cyto 338c Seq. ID No. 709 Seq. ID No. 710 Cyto 341a Seq. ID No. 711 Seq. ID No. 712 Cyto 0 341b Seq. ID No. 713 Seq. ID No. 714 Cyto 0 342g Seq. ID No. 727 Seq. ID No. 728 IM 12 342h Seq. ID No. 729 Seq. ID No. 730 IM 12 344a Seq. ID No. 731 Seq. ID No. 732 IM 1 344b Seq. ID No. 733 Seq. ID No. 734 IM 1 345 Seq. ID No. 735 Seq. ID No. 736 Cyto 346a Seq. ID No. 737 Seq. ID No. 738 Cyto 346b Seq. ID No. 739 Seq. ID No. 740 Cyto 0 347 Seq. ID No. 741 Seq. ID No. 742 Cyto 349a Seq. ID No. 743 Seq. ID No. 744 Cyto 351 Seq. ID No. 753 Seq. ID No. 754 Cyto 1 355 Seq. ID No. 767 Seq. ID No. 768 Cyto 0 356b Seq. ID No. 771 Seq. ID No. 772 IM 4 356c Seq. ID No. 773 Seq. ID No. 774 IM 4 356d Seq. ID No. 775 Seq. ID No. 776 IM 5 362 Seq. ID No. 783 Seq. ID No. 784 IM 2 365a Seq. ID No. 785 Seq. ID No. 786 Cyto 365b Seq. ID No. 787 Seq. ID No. 788 Cyto 366b Seq. ID No. 789 Seq. ID No. 790 Cyto 366c Seq. ID No. 791 Seq. ID No. 792 Cyto 367a Seq. ID No. 793 Seq. ID No. 794 Cyto 1 367b Seq. ID No. 795 Seq. ID No. 796 Cyto 1 371a Seq. ID No. 797 Seq. ID No. 798 Cyto 371b Seq. ID No. 799 Seq. ID No. 800 Cyto 372a Seq. ID No. 801 Seq. ID No. 802 Cyto 372b Seq. ID No. 803 Seq. ID No. 804 Cyto 372c Seq. ID No. 805 Seq. ID No. 806 OM 377a Seq. ID No. 811 Seq. ID No. 812 Cyto 1 377b Seq. ID No. 813 Seq. ID No. 814 Cyto 1 378a Seq. ID No. 815 Seq. ID No. 816 IM 1 378b Seq. ID No. 817 Seq. ID No. 818 IM 1 383a Seq. ID No. 821 Seq. ID No. 822 Cyto 383b Seq. ID No. 823 Seq. ID No. 824 Cyto 1 384b Seq. ID No. 827 Seq. ID No. 828 IM 10 385a Seq. ID No. 829 Seq. ID No. 830 IM 0 385b Seq. ID No. 831 Seq. ID No. 832 IM 0 386 Seq. ID No. 833 Seq. ID No. 834 Cyto 387 Seq. ID No. 835 Seq. ID No. 836 Cyto 390 Seq. ID No. 837 Seq. ID No. 838 IM 391 Seq. ID No. 839 Seq. ID No. 840 Peri 393b Seq. ID No. 841 Seq. ID No. 842 Cyto 395a Seq. ID No. 843 Seq. ID No. 844 IM 6 395b Seq. ID No. 845 Seq. ID No. 846 IM 6 395c Seq. ID No. 847 Seq. ID No. 848 IM 6 396 Seq. ID No. 849 Seq. ID No. 850 Peri 2 398 Seq. ID No. 851 Seq. ID No. 852 IM 2 400a Seq. ID No. 853 Seq. ID No. 854 IM 0 400b Seq. ID No. 855 Seq. ID No. 856 IM 0 401a Seq. ID No. 857 Seq. ID No. 858 Cyto 401b Seq. ID No. 859 Seq. ID No. 860 Cyto 403a Seq. ID No. 861 Seq. ID No. 862 Cyto 1 403c Seq. ID No. 865 Seq. ID No. 866 Cyto 2 403d Seq. ID No. 867 Seq. ID No. 868 Cyto 2 406a Seq. ID No. 869 Seq. ID No. 870 Cyto 406b Seq. ID No. 871 Seq. ID No. 872 Cyto 409a Seq. ID No. 873 Seq. ID No. 874 Cyto 0 409b Seq. ID No. 875 Seq. ID No. 876 Cyto 0 410a Seq. ID No. 877 Seq. ID No. 878 Cyto 0 410b Seq. ID No. 879 Seq. ID No. 880 IM 1 410c Seq. ID No. 881 Seq. ID No. 882 IM 1 413a Seq. ID No. 883 Seq. ID No. 884 Cyto 413b Seq. ID No. 885 Seq. ID No. 886 Cyto 416a Seq. ID No. 887 Seq. ID No. 888 Cyto 416b Seq. ID No. 889 Seq. ID No. 890 Cyto 417 Seq. ID No. 891 Seq. ID No. 892 Cyto 418b Seq. ID No. 895 Seq. ID No. 896 IM 7 419a Seq. ID No. 897 Seq. ID No. 898 IM 1 419b Seq. ID No. 899 Seq. ID No. 900 IM 1 420a Seq. ID No. 903 Seq. ID No. 904 IM 1 420b Seq. ID No. 905 Seq. ID No. 906 IM 1 421 Seq. ID No. 907 Seq. ID No. 908 IM 1 422 Seq. ID No. 909 Seq. ID No. 910 Cyto 424a Seq. ID No. 911 Seq. ID No. 912 Cyto 0 424b Seq. ID No. 913 Seq. ID No. 914 IM 1 424c Seq. ID No. 915 Seq. ID No. 916 IM 1 426a Seq. ID No. 917 Seq. ID No. 918 Cyto 426b Seq. ID No. 919 Seq. ID No. 920 Cyto 427a Seq. ID No. 921 Seq. ID No. 922 Cyto 427b Seq. ID No. 923 Seq. ID No. 924 Cyto 427c Seq. ID No. 925 Seq. ID No. 926 Cyto 429a Seq. ID No. 927 Seq. ID No. 928 Cyto 429b Seq. ID No. 929 Seq. ID No. 930 OM 0 429c Seq. ID No. 931 Seq. ID No. 932 Cyto 0 429d Seq. ID No. 933 Seq. ID No. 934 Cyto 0 435 Seq. ID No. 939 Seq. ID No. 940 Cyto 438a Seq. ID No. 945 Seq. ID No. 946 IM 1 438b Seq. ID No. 947 Seq. ID No. 948 IM 1 438c Seq. ID No. 949 Seq. ID No. 950 IM 1 440 Seq. ID No. 951 Seq. ID No. 952 IM 2 441a Seq. ID No. 953 Seq. ID No. 954 IM 1 444a Seq. ID No. 959 Seq. ID No. 960 Cyto 444b Seq. ID No. 961 Seq. ID No. 962 Cyto 445a Seq. ID No. 963 Seq. ID No. 964 Cyto 0 445b Seq. ID No. 965 Seq. ID No. 966 Cyto 0 450a Seq. ID No. 969 Seq. ID No. 970 Cyto 0 450b Seq. ID No. 971 Seq. ID No. 972 Cyto 0 451a Seq. ID No. 973 Seq. ID No. 974 Peri 451b Seq. ID No. 975 Seq. ID No. 976 Peri 452a Seq. ID No. 977 Seq. ID No. 978 IM 4 454b Seq. ID No. 987 Seq. ID No. 988 Cyto 455a Seq. ID No. 989 Seq. ID No. 990 IM 0 455b Seq. ID No. 991 Seq. ID No. 992 IM 0 455c Seq. ID No. 993 Seq. ID No. 994 IM 0 458a Seq. ID No. 995 Seq. ID No. 996 Cyto 458b Seq. ID No. 997 Seq. ID No. 998 Cyto 460a Seq. ID No. 999 Seq. ID No. 1000 Cyto 1 464d Seq. ID No. 1017 Seq. ID No. 1018 IM 13 467a Seq. ID No. 1021 Seq. ID No. 1022 Cyto 0 467b Seq. ID No. 1023 Seq. ID No. 1024 Cyto 0 471a Seq. ID No. 1025 Seq. ID No. 1026 Cyto 1 471b Seq. ID No. 1027 Seq. ID No. 1028 Cyto 1 473 Seq. ID No. 1041 Seq. ID No. 1042 IM 2 474 Seq. ID No. 1043 Seq. ID No. 1044 Cyto 0 477b Seq. ID No. 1047 Seq. ID No. 1048 Cyto 0 478a Seq. ID No. 1049 Seq. ID No. 1050 IM 1 478b Seq. ID No. 1051 Seq. ID No. 1052 IM 1 479 Seq. ID No. 1053 Seq. ID No. 1054 Cyto 480b Seq. ID No. 1057 Seq. ID No. 1058 Cyto 1 481a Seq. ID No. 1059 Seq. ID No. 1060 Cyto 481b Seq. ID No. 1061 Seq. ID No. 1062 Cyto 482a Seq. ID No. 1063 Seq. ID No. 1064 Cyto 482b Seq. ID No. 1065 Seq. ID No. 1066 Cyto 483 Seq. ID No. 1067 Seq. ID No. 1068 Cyto 490 Seq. ID No. 1069 Seq. ID No. 1070 Cyto 491a Seq. ID No. 1071 Seq. ID No. 1072 Cyto 491b Seq. ID No. 1073 Seq. ID No. 1074 Cyto 495a Seq. ID No. 1079 Seq. ID No. 1080 Cyto 0 495b Seq. ID No. 1081 Seq. ID No. 1082 Cyto 0 495c Seq. ID No. 1083 Seq. ID No. 1084 IM 0 498a Seq. ID No. 1085 Seq. ID No. 1086 Cyto 498b Seq. ID No. 1087 Seq. ID No. 1088 Cyto 499a Seq. ID No. 1089 Seq. ID No. 1090 IM 2 499b Seq. ID No. 1091 Seq. ID No. 1092 IM 2 500 Seq. ID No. 1093 Seq. ID No. 1094 Cyto 502b Seq. ID No. 1095 Seq. ID No. 1096 Cyto 502c Seq. ID No. 1097 Seq. ID No. 1098 Cyto 504 Seq. ID No. 1099 Seq. ID No. 1100 Cyto 505a Seq. ID No. 1101 Seq. ID No. 1102 Cyto 1 505b Seq. ID No. 1103 Seq. ID No. 1104 Cyto 1 509 Seq. ID No. 1109 Seq. ID No. 1110 Cyto 510 Seq. ID No. 1111 Seq. ID No. 1112 Cyto 512a Seq. ID No. 1113 Seq. ID No. 1114 Cyto 512b Seq. ID No. 1115 Seq. ID No. 1116 Cyto 514 Seq. ID No. 1117 Seq. ID No. 1118 Cyto 515a Seq. ID No. 1119 Seq. ID No. 1120 Cyto 515b Seq. ID No. 1121 Seq. ID No. 1122 IM 515c Seq. ID No. 1123 Seq. ID No. 1124 Cyto 518a Seq. ID No. 1125 Seq. ID No. 1126 Cyto 0 518b Seq. ID No. 1127 Seq. ID No. 1128 Cyto 0 518c Seq. ID No. 1129 Seq. ID No. 1130 Cyto 0 523 Seq. ID No. 1133 Seq. ID No. 1134 Cyto 527a Seq. ID No. 1141 Seq. ID No. 1142 Cyto 527b Seq. ID No. 1143 Seq. ID No. 1144 Cyto 528a Seq. ID No. 1145 Seq. ID No. 1146 IM 1 528b Seq. ID No. 1147 Seq. ID No. 1148 IM 1 529 Seq. ID No. 1149 Seq. ID No. 1150 Cyto 0 530b Seq. ID No. 1153 Seq. ID No. 1154 Peri 533 Seq. ID No. 1155 Seq. ID No. 1156 IM 9 535 Seq. ID No. 1157 Seq. ID No. 1158 Cyto 536 Seq. ID No. 1159 Seq. ID No. 1160 Cyto 1 539b Seq. ID No. 1161 Seq. ID No. 1162 Cyto 539c Seq. ID No. 1163 Seq. ID No. 1164 Cyto 541d Seq. ID No. 1171 Seq. ID No. 1172 IM 5 543a Seq. ID No. 1175 Seq. ID No. 1176 Cyto 543b Seq. ID No. 1177 Seq. ID No. 1178 Cyto 543c Seq. ID No. 1179 Seq. ID No. 1180 Cyto 544 Seq. ID No. 1181 Seq. ID No. 1182 IM 4 545b Seq. ID No. 1185 Seq. ID No. 1186 IM 3 545c Seq. ID No. 1187 Seq. ID No. 1188 IM 4 546a Seq. ID No. 1189 Seq. ID No. 1190 Cyto 546b Seq. ID No. 1191 Seq. ID No. 1192 IM 1 546c Seq. ID No. 1193 Seq. ID No. 1194 IM 1 548 Seq. ID No. 1199 Seq. ID No. 1200 IM 2 549b Seq. ID No. 1201 Seq. ID No. 1202 IM 2 551 Seq. ID No. 1205 Seq. ID No. 1206 IM 1 553c Seq. ID No. 1207 Seq. ID No. 1208 IM 1 554a Seq. ID No. 1209 Seq. ID No. 1210 Cyto 1 554b Seq. ID No. 1211 Seq. ID No. 1212 Cyto 1 557a Seq. ID No. 1215 Seq. ID No. 1216 Cyto 0 557b Seq. ID No. 1217 Seq. ID No. 1218 Cyto 0 560a Seq. ID No. 1219 Seq. ID No. 1220 IM 0 560b Seq. ID No. 1221 Seq. ID No. 1222 IM 0 563 Seq. ID No. 1225 Seq. ID No. 1226 IM 0 564c Seq. ID No. 1231 Seq. ID No. 1232 IM 5 569 Seq. ID No. 1233 Seq. ID No. 1234 Cyto 570a Seq. ID No. 1235 Seq. ID No. 1236 IM 1 571 Seq. ID No. 1239 Seq. ID No. 1240 Peri 0 573 Seq. ID No. 1241 Seq. ID No. 1242 IM 5 578a Seq. ID No. 1247 Seq. ID No. 1248 Cyto 0 578b Seq. ID No. 1249 Seq. ID No. 1250 Cyto 0 580a Seq. ID No. 1251 Seq. ID No. 1252 Cyto 580b Seq. ID No. 1253 Seq. ID No. 1254 Cyto 583a Seq. ID No. 1255 Seq. ID No. 1256 IM 0 583b Seq. ID No. 1257 Seq. ID No. 1258 IM 0 586a Seq. ID No. 1261 Seq. ID No. 1262 IM 2 586b Seq. ID No. 1263 Seq. ID No. 1264 IM 2 588a Seq. ID No. 1273 Seq. ID No. 1274 Cyto 1 588b Seq. ID No. 1275 Seq. ID No. 1276 Cyto 1 589a Seq. ID No. 1277 Seq. ID No. 1278 Cyto 1 589b Seq. ID No. 1279 Seq. ID No. 1280 Cyto 1 590 Seq. ID No. 1281 Seq. ID No. 1282 IM 2 595b Seq. ID No. 1285 Seq. ID No. 1286 IM 2 597 Seq. ID No. 1293 Seq. ID No. 1294 IM 3 599a Seq. ID No. 1299 Seq. ID No. 1300 IM 2 599b Seq. ID No. 1301 Seq. ID No. 1302 IM 2 603a Seq. ID No. 1307 Seq. ID No. 1308 Cyto 1 606 Seq. ID No. 1309 Seq. ID No. 1310 Cyto 607a Seq. ID No. 1311 Seq. ID No. 1312 IM 0 607b Seq. ID No. 1313 Seq. ID No. 1314 IM 0 610b Seq. ID No. 1321 Seq. ID No. 1322 IM 1 611 Seq. ID No. 1323 Seq. ID No. 1324 Peri 0 614a Seq. ID No. 1333 Seq. ID No. 1334 Cyto 614b Seq. ID No. 1335 Seq. ID No. 1336 Cyto 618 Seq. ID No. 1339 Seq. ID No. 1340 IM 4 620 Seq. ID No. 1345 Seq. ID No. 1346 Cyto 625 Seq. ID No. 1355 Seq. ID No. 1356 Cyto 626a Seq. ID No. 1357 Seq. ID No. 1358 Cyto 0 626b Seq. ID No. 1359 Seq. ID No. 1360 Cyto 0 626c Seq. ID No. 1361 Seq. ID No. 1362 Cyto 0 631a Seq. ID No. 1363 Seq. ID No. 1364 IM 1 633a Seq. ID No. 1373 Seq. ID No. 1374 IM 0 633b Seq. ID No. 1375 Seq. ID No. 1376 IM 0 633c Seq. ID No. 1377 Seq. ID No. 1378 Cyto 0 634b Seq. ID No. 1379 Seq. ID No. 1380 Cyto 637a Seq. ID No. 1383 Seq. ID No. 1384 IM 0 637b Seq. ID No. 1385 Seq. ID No. 1386 IM 0 637c Seq. ID No. 1387 Seq. ID No. 1388 IM 0 640 Seq. ID No. 1389 Seq. ID No. 1390 Cyto 0 641a Seq. ID No. 1391 Seq. ID No. 1392 IM 1 641b Seq. ID No. 1393 Seq. ID No. 1394 IM 1 643 Seq. ID No. 1395 Seq. ID No. 1396 IM 1 644a Seq. ID No. 1397 Seq. ID No. 1398 Cyto 644b Seq. ID No. 1399 Seq. ID No. 1400 Cyto 650 Seq. ID No. 1403 Seq. ID No. 1404 Cyto 652 Seq. ID No. 1405 Seq. ID No. 1406 Cyto 653a Seq. ID No. 1407 Seq. ID No. 1408 Cyto 1 653b Seq. ID No. 1409 Seq. ID No. 1410 Cyto 1 653c Seq. ID No. 1411 Seq. ID No. 1412 Cyto 1 656 Seq. ID No. 1413 Seq. ID No. 1414 Cyto 0 657c Seq. ID No. 1415 Seq. ID No. 1416 Cyto 658a Seq. ID No. 1417 Seq. ID No. 1418 IM 4 658b Seq. ID No. 1419 Seq. ID No. 1420 IM 4 659a Seq. ID No. 1421 Seq. ID No. 1422 Cyto 659b Seq. ID No. 1423 Seq. ID No. 1424 Cyto 661 Seq. ID No. 1425 Seq. ID No. 1426 Cyto 663 Seq. ID No. 1427 Seq. ID No. 1428 Cyto 0 666 Seq. ID No. 1431 Seq. ID No. 1432 IM 4 670 Seq. ID No. 1433 Seq. ID No. 1434 Cyto 1 674b Seq. ID No. 1437 Seq. ID No. 1438 IM 1 676 Seq. ID No. 1439 Seq. ID No. 1440 Cyto 677a Seq. ID No. 1441 Seq. ID No. 1442 Cyto 0 677b Seq. ID No. 1443 Seq. ID No. 1444 Cyto 0 680 Seq. ID No. 1449 Seq. ID No. 1450 Cyto 0 681 Seq. ID No. 1451 Seq. ID No. 1452 Cyto 0 683a Seq. ID No. 1453 Seq. ID No. 1454 Cyto 683b Seq. ID No. 1455 Seq. ID No. 1456 Cyto 684 Seq. ID No. 1457 Seq. ID No. 1458 Cyto 687 Seq. ID No. 1459 Seq. ID No. 1460 Peri 688a Seq. ID No. 1461 Seq. ID No. 1462 IM 4 688b Seq. ID No. 1463 Seq. ID No. 1464 IM 4 690 Seq. ID No. 1465 Seq. ID No. 1466 Cyto 691a Seq. ID No. 1467 Seq. ID No. 1468 Cyto 691b Seq. ID No. 1469 Seq. ID No. 1470 Cyto 692 Seq. ID No. 1471 Seq. ID No. 1472 IM 0 694 Seq. ID No. 1473 Seq. ID No. 1474 Cyto 696 Seq. ID No. 1475 Seq. ID No. 1476 Cyto 698 Seq. ID No. 1477 Seq. ID No. 1478 IM 4 699b Seq. ID No. 1479 Seq. ID No. 1480 IM 1 700b Seq. ID No. 1483 Seq. ID No. 1484 IM 7 700c Seq. ID No. 1485 Seq. ID No. 1486 IM 7 703 Seq. ID No. 1487 Seq. ID No. 1488 IM 0 705a Seq. ID No. 1489 Seq. ID No. 1490 Cyto 0 705b Seq. ID No. 1491 Seq. ID No. 1492 Cyto 0 707 Seq. ID No. 1493 Seq. ID No. 1494 Cyto 709 Seq. ID No. 1495 Seq. ID No. 1496 Cyto 710 Seq. ID No. 1497 Seq. ID No. 1498 Cyto 712a Seq. ID No. 1499 Seq. ID No. 1500 Cyto 712b Seq. ID No. 1501 Seq. ID No. 1502 Cyto 715a Seq. ID No. 1503 Seq. ID No. 1504 Cyto 0 715b Seq. ID No. 1505 Seq. ID No. 1506 Cyto 0 717 Seq. ID No. 1507 Seq. ID No. 1508 Cyto 718a Seq. ID No. 1509 Seq. ID No. 1510 Cyto 721 Seq. ID No. 1511 Seq. ID No. 1512 Cyto 724a Seq. ID No. 1519 Seq. ID No. 1520 Cyto 0 724b Seq. ID No. 1521 Seq. ID No. 1522 Cyto 0 724c Seq. ID No. 1523 Seq. ID No. 1524 Cyto 0 724d Seq. ID No. 1525 Seq. ID No. 1526 Cyto 0 726 Seq. ID No. 1527 Seq. ID No. 1528 Cyto 728b Seq. ID No. 1531 Seq. ID No. 1532 IM 8 730c Seq. ID No. 1537 Seq. ID No. 1538 IM 5 730d Seq. ID No. 1539 Seq. ID No. 1540 IM 5 731b Seq. ID No. 1541 Seq. ID No. 1542 Cyto 1 732 Seq. ID No. 1543 Seq. ID No. 1544 Cyto 2 738c Seq. ID No. 1549 Seq. ID No. 1550 IM 10 741a Seq. ID No. 1555 Seq. ID No. 1556 Cyto 741b Seq. ID No. 1557 Seq. ID No. 1558 Cyto 745a Seq. ID No. 1565 Seq. ID No. 1566 IM 6 745b Seq. ID No. 1567 Seq. ID No. 1568 IM 6 746a Seq. ID No. 1569 Seq. ID No. 1570 IM 6 747 Seq. ID No. 1573 Seq. ID No. 1574 Cyto 748a Seq. ID No. 1575 Seq. ID No. 1576 Cyto 748b Seq. ID No. 1577 Seq. ID No. 1578 Cyto 751 Seq. ID No. 1581 Seq. ID No. 1582 IM 1 754c Seq. ID No. 1587 Seq. ID No. 1588 IM 9 754d Seq. ID No. 1589 Seq. ID No. 1590 IM 9 756a Seq. ID No. 1591 Seq. ID No. 1592 Cyto 1 756b Seq. ID No. 1593 Seq. ID No. 1594 Cyto 1 758 Seq. ID No. 1595 Seq. ID No. 1596 Cyto 760 Seq. ID No. 1597 Seq. ID No. 1598 Cyto 762b Seq. ID No. 1601 Seq. ID No. 1602 Cyto 0 762c Seq. ID No. 1603 Seq. ID No. 1604 Cyto 0 763a Seq. ID No. 1605 Seq. ID No. 1606 Cyto 763b Seq. ID No. 1607 Seq. ID No. 1608 Cyto 764 Seq. ID No. 1609 Seq. ID No. 1610 Cyto 766 Seq. ID No. 1611 Seq. ID No. 1612 Cyto 0 767 Seq. ID No. 1613 Seq. ID No. 1614 Cyto 770a Seq. ID No. 1615 Seq. ID No. 1616 IM 770b Seq. ID No. 1617 Seq. ID No. 1618 Cyto 770c Seq. ID No. 1619 Seq. ID No. 1620 Cyto 772b Seq. ID No. 1623 Seq. ID No. 1624 IM 6 774 Seq. ID No. 1625 Seq. ID No. 1626 Cyto 0 775 Seq. ID No. 1627 Seq. ID No. 1628 IM 7 777a Seq. ID No. 1629 Seq. ID No. 1630 Cyto 777c Seq. ID No. 1631 Seq. ID No. 1632 OM 780a Seq. ID No. 1635 Seq. ID No. 1636 Cyto 780b Seq. ID No. 1637 Seq. ID No. 1638 Cyto 785 Seq. ID No. 1641 Seq. ID No. 1642 Cyto 0 789b Seq. ID No. 1651 Seq. ID No. 1652 IM 4 791 Seq. ID No. 1655 Seq. ID No. 1656 Cyto 792 Seq. ID No. 1657 Seq. ID No. 1658 Cyto 794a Seq. ID No. 1659 Seq. ID No. 1660 Peri 0 795 Seq. ID No. 1667 Seq. ID No. 1668 Cyto 797 Seq. ID No. 1669 Seq. ID No. 1670 Cyto 799c Seq. ID No. 1675 Seq. ID No. 1676 IM 9 803a Seq. ID No. 1683 Seq. ID No. 1684 Cyto 3 803b Seq. ID No. 1685 Seq. ID No. 1686 Cyto 3 804a Seq. ID No. 1687 Seq. ID No. 1688 Cyto 804b Seq. ID No. 1689 Seq. ID No. 1690 Cyto 807 Seq. ID No. 1691 Seq. ID No. 1692 Cyto 809b Seq. ID No. 1695 Seq. ID No. 1696 IM 4 812 Seq. ID No. 1697 Seq. ID No. 1698 Cyto 0 813 Seq. ID No. 1699 Seq. ID No. 1700 IM 5 816 Seq. ID No. 1701 Seq. ID No. 1702 IM 0 820a Seq. ID No. 1703 Seq. ID No. 1704 IM 0 820b Seq. ID No. 1705 Seq. ID No. 1706 IM 0 829a Seq. ID No. 1709 Seq. ID No. 1710 Peri 830 Seq. ID No. 1713 Seq. ID No. 1714 Cyto 834a Seq. ID No. 1715 Seq. ID No. 1716 Cyto 834b Seq. ID No. 1717 Seq. ID No. 1718 Cyto 834c Seq. ID No. 1719 Seq. ID No. 1720 Cyto 835a Seq. ID No. 1721 Seq. ID No. 1722 Cyto 835b Seq. ID No. 1723 Seq. ID No. 1724 Cyto 836a Seq. ID No. 1725 Seq. ID No. 1726 Cyto 836b Seq. ID No. 1727 Seq. ID No. 1728 Cyto 836c Seq. ID No. 1729 Seq. ID No. 1730 Cyto 837c Seq. ID No. 1735 Seq. ID No. 1736 IM 8 847a Seq. ID No. 1739 Seq. ID No. 1740 IM 1 847b Seq. ID No. 1741 Seq. ID No. 1742 IM 1 848 Seq. ID No. 1743 Seq. ID No. 1744 Cyto 849a Seq. ID No. 1745 Seq. ID No. 1746 Cyto 849b Seq. ID No. 1747 Seq. ID No. 1748 IM 0 851a Seq. ID No. 1749 Seq. ID No. 1750 Cyto 851b Seq. ID No. 1751 Seq. ID No. 1752 Cyto 854 Seq. ID No. 1759 Seq. ID No. 1760 IM 2 855 Seq. ID No. 1761 Seq. ID No. 1762 Cyto 857 Seq. ID No. 1763 Seq. ID No. 1764 Peri 1 859c Seq. ID No. 1769 Seq. ID No. 1770 IM 6 860 Seq. ID No. 1773 Seq. ID No. 1774 Cyto 862 Seq. ID No. 1775 Seq. ID No. 1776 Peri 0 863 Seq. ID No. 1777 Seq. ID No. 1778 Cyto 864a Seq. ID No. 1779 Seq. ID No. 1780 Cyto 1 866a Seq. ID No. 1783 Seq. ID No. 1784 Cyto 866b Seq. ID No. 1785 Seq. ID No. 1786 Cyto 0 868b Seq. ID No. 1789 Seq. ID No. 1790 IM 6 873a Seq. ID No. 1793 Seq. ID No. 1794 Cyto 873b Seq. ID No. 1795 Seq. ID No. 1796 Cyto 874a Seq. ID No. 1799 Seq. ID No. 1800 Cyto 874b Seq. ID No. 1801 Seq. ID No. 1802 Cyto 875 Seq. ID No. 1803 Seq. ID No. 1804 Cyto 878a Seq. ID No. 1807 Seq. ID No. 1808 Cyto 878b Seq. ID No. 1809 Seq. ID No. 1810 Cyto 878c Seq. ID No. 1811 Seq. ID No. 1812 Cyto 0 880a Seq. ID No. 1813 Seq. ID No. 1814 IM 0 880b Seq. ID No. 1815 Seq. ID No. 1816 IM 0 880c Seq. ID No. 1817 Seq. ID No. 1818 IM 0 888 Seq. ID No. 1825 Seq. ID No. 1826 Cyto 890a Seq. ID No. 1827 Seq. ID No. 1828 Cyto 890b Seq. ID No. 1829 Seq. ID No. 1830 Cyto 894 Seq. ID No. 1831 Seq. ID No. 1832 Cyto 904 Seq. ID No. 1833 Seq. ID No. 1834 Peri 907a Seq. ID No. 1835 Seq. ID No. 1836 Cyto 1 907b Seq. ID No. 1837 Seq. ID No. 1838 Cyto 1 908b Seq. ID No. 1841 Seq. ID No. 1842 IM 9 908c Seq. ID No. 1843 Seq. ID No. 1844 IM 9 911 Seq. ID No. 1845 Seq. ID No. 1846 Cyto 912 Seq. ID No. 1847 Seq. ID No. 1848 Cyto 916 Seq. ID No. 1849 Seq. ID No. 1850 Cyto 1 917 Seq. ID No. 1851 Seq. ID No. 1852 Cyto 918b Seq. ID No. 1853 Seq. ID No. 1854 Cyto 918c Seq. ID No. 1855 Seq. ID No. 1856 Cyto 923 Seq. ID No. 1859 Seq. ID No. 1860 Cyto 0 925a Seq. ID No. 1861 Seq. ID No. 1862 Cyto 0 925b Seq. ID No. 1863 Seq. ID No. 1864 Cyto 0 926 Seq. ID No. 1865 Seq. ID No. 1866 Cyto 0 927 Seq. ID No. 1867 Seq. ID No. 1868 Cyto 929b Seq. ID No. 1871 Seq. ID No. 1872 Cyto 1 930 Seq. ID No. 1873 Seq. ID No. 1874 Cyto 1 932 Seq. ID No. 1877 Seq. ID No. 1878 Cyto 1 934a Seq. ID No. 1879 Seq. ID No. 1880 Cyto 934b Seq. ID No. 1881 Seq. ID No. 1882 Cyto 934c Seq. ID No. 1883 Seq. ID No. 1884 Cyto 0 934d Seq. ID No. 1885 Seq. ID No. 1886 Cyto 0 935 Seq. ID No. 1887 Seq. ID No. 1888 Cyto 0 938 Seq. ID No. 1889 Seq. ID No. 1890 Cyto 1 942 Seq. ID No. 1897 Seq. ID No. 1898 IM 943 Seq. ID No. 1899 Seq. ID No. 1900 Cyto 944a Seq. ID No. 1901 Seq. ID No. 1902 Cyto 0 944b Seq. ID No. 1903 Seq. ID No. 1904 Cyto 0 946 Seq. ID No. 1905 Seq. ID No. 1906 Cyto 0 949a Seq. ID No. 1907 Seq. ID No. 1908 Cyto 949b Seq. ID No. 1909 Seq. ID No. 1910 IM 1 949c Seq. ID No. 1911 Seq. ID No. 1912 IM 1 949d Seq. ID No. 1913 Seq. ID No. 1914 IM 1 952a Seq. ID No. 1921 Seq. ID No. 1922 IM 1 954 Seq. ID No. 1925 Seq. ID No. 1926 Cyto 0 956 Seq. ID No. 1931 Seq. ID No. 1932 IM 0 958a Seq. ID No. 1933 Seq. ID No. 1934 Cyto 958b Seq. ID No. 1935 Seq. ID No. 1936 Cyto 959 Seq. ID No. 1937 Seq. ID No. 1938 Cyto 961a Seq. ID No. 1939 Seq. ID No. 1940 Cyto 961b Seq. ID No. 1941 Seq. ID No. 1942 Cyto 961c Seq. ID No. 1943 Seq. ID No. 1944 Cyto 963 Seq. ID No. 1945 Seq. ID No. 1946 Cyto 0 965a Seq. ID No. 1947 Seq. ID No. 1948 Cyto 965b Seq. ID No. 1949 Seq. ID No. 1950 Cyto 966a Seq. ID No. 1951 Seq. ID No. 1952 Cyto 966b Seq. ID No. 1953 Seq. ID No. 1954 Cyto 967a Seq. ID No. 1955 Seq. ID No. 1956 IM 967b Seq. ID No. 1957 Seq. ID No. 1958 Cyto 968 Seq. ID No. 1959 Seq. ID No. 1960 Cyto 0 969 Seq. ID No. 1961 Seq. ID No. 1962 IM 972a Seq. ID No. 1963 Seq. ID No. 1964 IM 972b Seq. ID No. 1965 Seq. ID No. 1966 IM 976 Seq. ID No. 1967 Seq. ID No. 1968 Cyto 977b Seq. ID No. 1971 Seq. ID No. 1972 Cyto 1 978a Seq. ID No. 1973 Seq. ID No. 1974 Cyto 978b Seq. ID No. 1975 Seq. ID No. 1976 Cyto 979 Seq. ID No. 1977 Seq. ID No. 1978 IM 1 980 Seq. ID No. 1979 Seq. ID No. 1980 Cyto 0 982 Seq. ID No. 1983 Seq. ID No. 1984 Cyto 984a Seq. ID No. 1985 Seq. ID No. 1986 Cyto 984b Seq. ID No. 1987 Seq. ID No. 1988 Cyto 986 Seq. ID No. 1989 Seq. ID No. 1990 Cyto 988b Seq. ID No. 1995 Seq. ID No. 1996 IM 6 988c Seq. ID No. 1997 Seq. ID No. 1998 IM 6 988d Seq. ID No. 1999 Seq. ID No. 2000 IM 6 991 Seq. ID No. 2001 Seq. ID No. 2002 IM 992 Seq. ID No. 2003 Seq. ID No. 2004 Cyto 0 994 Seq. ID No. 2007 Seq. ID No. 2008 Cyto 2 995 Seq. ID No. 2009 Seq. ID No. 2010 IM 1 997 Seq. ID No. 2011 Seq. ID No. 2012 IM 998b Seq. ID No. 2015 Seq. ID No. 2016 IM 5 1000 Seq. ID No. 2021 Seq. ID No. 2022 Cyto 1 1001 Seq. ID No. 2023 Seq. ID No. 2024 Cyto 1004a Seq. ID No. 2029 Seq. ID No. 2030 IM 1 1004b Seq. ID No. 2031 Seq. ID No. 2032 IM 1 1007 Seq. ID No. 2037 Seq. ID No. 2038 Cyto 1012 Seq. ID No. 2039 Seq. ID No. 2040 IM 1 1013b Seq. ID No. 2043 Seq. ID No. 2044 IM 6 1013c Seq. ID No. 2045 Seq. ID No. 2046 IM 6 1016c Seq. ID No. 2047 Seq. ID No. 2048 Cyto 1017b Seq. ID No. 2051 Seq. ID No. 2052 IM 5 1018a Seq. ID No. 2057 Seq. ID No. 2058 Cyto 1018b Seq. ID No. 2059 Seq. ID No. 2060 Cyto 1021a Seq. ID No. 2061 Seq. ID No. 2062 Cyto 1 1021b Seq. ID No. 2063 Seq. ID No. 2064 Cyto 1 1021c Seq. ID No. 2065 Seq. ID No. 2066 Cyto 1 1024 Seq. ID No. 2067 Seq. ID No. 2068 Cyto 1025 Seq. ID No. 2069 Seq. ID No. 2070 Cyto 1026 Seq. ID No. 2071 Seq. ID No. 2072 Cyto 1029 Seq. ID No. 2073 Seq. ID No. 2074 Cyto 1033a Seq. ID No. 2075 Seq. ID No. 2076 IM 0 1033b Seq. ID No. 2077 Seq. ID No. 2078 IM 0 1033c Seq. ID No. 2079 Seq. ID No. 2080 IM 0 1035a Seq. ID No. 2081 Seq. ID No. 2082 IM 1 1035b Seq. ID No. 2083 Seq. ID No. 2084 IM 1 1035c Seq. ID No. 2085 Seq. ID No. 2086 IM 1 1037 Seq. ID No. 2093 Seq. ID No. 2094 Cyto 1039a Seq. ID No. 2095 Seq. ID No. 2096 Cyto 0 1039b Seq. ID No. 2097 Seq. ID No. 2098 Cyto 0 1041 Seq. ID No. 2099 Seq. ID No. 2100 Cyto 1042a Seq. ID No. 2101 Seq. ID No. 2102 Cyto 1 1042b Seq. ID No. 2103 Seq. ID No. 2104 Cyto 1 1044d Seq. ID No. 2111 Seq. ID No. 2112 IM 3 1049a Seq. ID No. 2117 Seq. ID No. 2118 Cyto 0 1049b Seq. ID No. 2119 Seq. ID No. 2120 Cyto 0 1055 Seq. ID No. 2129 Seq. ID No. 2130 Cyto 1056a Seq. ID No. 2131 Seq. ID No. 2132 Cyto 1056b Seq. ID No. 2133 Seq. ID No. 2134 Cyto 1057 Seq. ID No. 2135 Seq. ID No. 2136 Cyto 0 1058 Seq. ID No. 2137 Seq. ID No. 2138 Cyto 1 1060a Seq. ID No. 2139 Seq. ID No. 2140 IM 1 1060b Seq. ID No. 2141 Seq. ID No. 2142 IM 1 1062 Seq. ID No. 2143 Seq. ID No. 2144 Cyto 1063 Seq. ID No. 2145 Seq. ID No. 2146 Cyto 1 1064 Seq. ID No. 2147 Seq. ID No. 2148 Cyto 1065c Seq. ID No. 2153 Seq. ID No. 2154 IM 1 1069 Seq. ID No. 2161 Seq. ID No. 2162 IM 1 1070a Seq. ID No. 2163 Seq. ID No. 2164 Cyto 1070b Seq. ID No. 2165 Seq. ID No. 2166 Cyto 1076a Seq. ID No. 2167 Seq. ID No. 2168 IM 2 1076b Seq. ID No. 2169 Seq. ID No. 2170 IM 2 1077c Seq. ID No. 2175 Seq. ID No. 2176 IM 12 1077e Seq. ID No. 2179 Seq. ID No. 2180 IM 15 1079a Seq. ID No. 2181 Seq. ID No. 2182 Cyto 1079b Seq. ID No. 2183 Seq. ID No. 2184 Cyto 1080a Seq. ID No. 2185 Seq. ID No. 2186 Cyto 1081b Seq. ID No. 2189 Seq. ID No. 2190 IM 1 1085 Seq. ID No. 2193 Seq. ID No. 2194 Cyto 1086 Seq. ID No. 2195 Seq. ID No. 2196 IM 1 1087a Seq. ID No. 2197 Seq. ID No. 2198 IM 0 1087b Seq. ID No. 2199 Seq. ID No. 2200 IM 0 1091a Seq. ID No. 2201 Seq. ID No. 2202 Cyto 1091b Seq. ID No. 2203 Seq. ID No. 2204 Peri 1094b Seq. ID No. 2207 Seq. ID No. 2208 IM 2 1095a Seq. ID No. 2209 Seq. ID No. 2210 Cyto 1095b Seq. ID No. 2211 Seq. ID No. 2212 Cyto 1096a Seq. ID No. 2213 Seq. ID No. 2214 Cyto 0 1096b Seq. ID No. 2215 Seq. ID No. 2216 Cyto 0 1096c Seq. ID No. 2217 Seq. ID No. 2218 Cyto 0 1097 Seq. ID No. 2219 Seq. ID No. 2220 IM 2 1098b Seq. ID No. 2221 Seq. ID No. 2222 IM 2 1100 Seq. ID No. 2223 Seq. ID No. 2224 Cyto 1101a Seq. ID No. 2225 Seq. ID No. 2226 Cyto 1101b Seq. ID No. 2227 Seq. ID No. 2228 Cyto 1104 Seq. ID No. 2229 Seq. ID No. 2230 Cyto 1106 Seq. ID No. 2231 Seq. ID No. 2232 Cyto 1108a Seq. ID No. 2233 Seq. ID No. 2234 Cyto 1108b Seq. ID No. 2235 Seq. ID No. 2236 Cyto 1111c Seq. ID No. 2241 Seq. ID No. 2242 IM 8 1112a Seq. ID No. 2243 Seq. ID No. 2244 IM 1 1126a Seq. ID No. 2247 Seq. ID No. 2248 IM 3 1127 Seq. ID No. 2253 Seq. ID No. 2254 Cyto 1131 Seq. ID No. 2257 Seq. ID No. 2258 Cyto 1 1135a Seq. ID No. 2261 Seq. ID No. 2262 IM 1 1135b Seq. ID No. 2263 Seq. ID No. 2264 IM 1 1136a Seq. ID No. 2265 Seq. ID No. 2266 IM 1136b Seq. ID No. 2267 Seq. ID No. 2268 IM 1138 Seq. ID No. 2269 Seq. ID No. 2270 Cyto 1140b Seq. ID No. 2273 Seq. ID No. 2274 IM 3 1140c Seq. ID No. 2275 Seq. ID No. 2276 IM 6 1141a Seq. ID No. 2277 Seq. ID No. 2278 Cyto 1 1141b Seq. ID No. 2279 Seq. ID No. 2280 Cyto 1 1142 Seq. ID No. 2281 Seq. ID No. 2282 Cyto 1144b Seq. ID No. 2285 Seq. ID No. 2286 IM 4 1144c Seq. ID No. 2287 Seq. ID No. 2288 IM 5 1146e Seq. ID No. 2297 Seq. ID No. 2298 IM 10 1148 Seq. ID No. 2299 Seq. ID No. 2300 Cyto 0 1149 Seq. ID No. 2301 Seq. ID No. 2302 IM 0 1152d Seq. ID No. 2309 Seq. ID No. 2310 IM 7 1152e Seq. ID No. 2311 Seq. ID No. 2312 IM 8 1152f Seq. ID No. 2313 Seq. ID No. 2314 IM 8 1152g Seq. ID No. 2315 Seq. ID No. 2316 IM 8 1158a Seq. ID No. 2331 Seq. ID No. 2332 Cyto 1160 Seq. ID No. 2335 Seq. ID No. 2336 Cyto 1161a Seq. ID No. 2337 Seq. ID No. 2338 Cyto 1161b Seq. ID No. 2339 Seq. ID No. 2340 Cyto 1162 Seq. ID No. 2341 Seq. ID No. 2342 Cyto 1166 Seq. ID No. 2345 Seq. ID No. 2346 Cyto 1170 Seq. ID No. 2359 Seq. ID No. 2360 Cyto 0 1171a Seq. ID No. 2361 Seq. ID No. 2362 Cyto 1171c Seq. ID No. 2363 Seq. ID No. 2364 Cyto 1174 Seq. ID No. 2369 Seq. ID No. 2370 Cyto 2 1177 Seq. ID No. 2373 Seq. ID No. 2374 Cyto 1 1179a Seq. ID No. 2377 Seq. ID No. 2378 Cyto 0 1179b Seq. ID No. 2379 Seq. ID No. 2380 Cyto 0 1179c Seq. ID No. 2381 Seq. ID No. 2382 Cyto 0 1180a Seq. ID No. 2383 Seq. ID No. 2384 Cyto 1 1180b Seq. ID No. 2385 Seq. ID No. 2386 IM 2 1182b Seq. ID No. 2395 Seq. ID No. 2396 IM 2 1183a Seq. ID No. 2397 Seq. ID No. 2398 IM 0 1183b Seq. ID No. 2399 Seq. ID No. 2400 IM 0 1184 Seq. ID No. 2401 Seq. ID No. 2402 Cyto 1 1185a Seq. ID No. 2403 Seq. ID No. 2404 Cyto 0 1185b Seq. ID No. 2405 Seq. ID No. 2406 Cyto 0 1186b Seq. ID No. 2409 Seq. ID No. 2410 IM 5 1188a Seq. ID No. 2411 Seq. ID No. 2412 IM 2 1188b Seq. ID No. 2413 Seq. ID No. 2414 IM 4 1188c Seq. ID No. 2415 Seq. ID No. 2416 IM 4 1191 Seq. ID No. 2417 Seq. ID No. 2418 IM 0 1194 Seq. ID No. 2423 Seq. ID No. 2424 IM 1 1198 Seq. ID No. 2431 Seq. ID No. 2432 Cyto 1199b Seq. ID No. 2435 Seq. ID No. 2436 IM 3 1200 Seq. ID No. 2437 Seq. ID No. 2438 Cyto 0 1201 Seq. ID No. 2439 Seq. ID No. 2440 Cyto 1202a Seq. ID No. 2441 Seq. ID No. 2442 IM 3 1202b Seq. ID No. 2443 Seq. ID No. 2444 IM 3 1205 Seq. ID No. 2445 Seq. ID No. 2446 IM 3 1206 Seq. ID No. 2447 Seq. ID No. 2448 Cyto 0 1208 Seq. ID No. 2451 Seq. ID No. 2452 Cyto 1209 Seq. ID No. 2453 Seq. ID No. 2454 IM 4 1210a Seq. ID No. 2455 Seq. ID No. 2456 IM 3 1210b Seq. ID No. 2457 Seq. ID No. 2458 IM 4 1213a Seq. ID No. 2461 Seq. ID No. 2462 Cyto 1 1213b Seq. ID No. 2463 Seq. ID No. 2464 Cyto 1 1214 Seq. ID No. 2465 Seq. ID No. 2466 IM 1215a Seq. ID No. 2467 Seq. ID No. 2468 Cyto 0 1215b Seq. ID No. 2469 Seq. ID No. 2470 Cyto 0 1217c Seq. ID No. 2471 Seq. ID No. 2472 Cyto 1218a Seq. ID No. 2473 Seq. ID No. 2474 IM 2 1218b Seq. ID No. 2475 Seq. ID No. 2476 IM 2 1219 Seq. ID No. 2477 Seq. ID No. 2478 Cyto 1220 Seq. ID No. 2479 Seq. ID No. 2480 Cyto 1221a Seq. ID No. 2481 Seq. ID No. 2482 IM 1221b Seq. ID No. 2483 Seq. ID No. 2484 IM 1223 Seq. ID No. 2485 Seq. ID No. 2486 Cyto 1226 Seq. ID No. 2495 Seq. ID No. 2496 Cyto 1230 Seq. ID No. 2505 Seq. ID No. 2506 Cyto 0 1233a Seq. ID No. 2509 Seq. ID No. 2510 IM 1233b Seq. ID No. 2511 Seq. ID No. 2512 IM 1233c Seq. ID No. 2513 Seq. ID No. 2514 IM 1234c Seq. ID No. 2519 Seq. ID No. 2520 IM 6 1235 Seq. ID No. 2521 Seq. ID No. 2522 Cyto 1 1240 Seq. ID No. 2529 Seq. ID No. 2530 Cyto 1244 Seq. ID No. 2539 Seq. ID No. 2540 Cyto 0 1245d Seq. ID No. 2547 Seq. ID No. 2548 IM 12 1245e Seq. ID No. 2549 Seq. ID No. 2550 IM 12 1246a Seq. ID No. 2551 Seq. ID No. 2552 Cyto 1246b Seq. ID No. 2553 Seq. ID No. 2554 Cyto 1250c Seq. ID No. 2559 Seq. ID No. 2560 IM 9 1250d Seq. ID No. 2561 Seq. ID No. 2562 IM 10 1250e Seq. ID No. 2563 Seq. ID No. 2564 IM 10 1251b Seq. ID No. 2567 Seq. ID No. 2568 IM 3 1253c Seq. ID No. 2573 Seq. ID No. 2574 IM 7 1253d Seq. ID No. 2575 Seq. ID No. 2576 IM 7 1256 Seq. ID No. 2577 Seq. ID No. 2578 Cyto 1 1257a Seq. ID No. 2579 Seq. ID No. 2580 Cyto 1257b Seq. ID No. 2581 Seq. ID No. 2582 Cyto 1258b Seq. ID No. 2585 Seq. ID No. 2586 IM 7 1258c Seq. ID No. 2587 Seq. ID No. 2588 IM 7 1258d Seq. ID No. 2589 Seq. ID No. 2590 IM 7 1263 Seq. ID No. 2593 Seq. ID No. 2594 Cyto 0 1265 Seq. ID No. 2595 Seq. ID No. 2596 Cyto 1 1267b Seq. ID No. 2603 Seq. ID No. 2604 IM 3 1268a Seq. ID No. 2605 Seq. ID No. 2606 IM 3 1269 Seq. ID No. 2609 Seq. ID No. 2610 Cyto 1271 Seq. ID No. 2613 Seq. ID No. 2614 Cyto 1272a Seq. ID No. 2615 Seq. ID No. 2616 Cyto 1272b Seq. ID No. 2617 Seq. ID No. 2618 Cyto 0 1273 Seq. ID No. 2619 Seq. ID No. 2620 Cyto 0 1275b Seq. ID No. 2623 Seq. ID No. 2624 Cyto 1 1277 Seq. ID No. 2625 Seq. ID No. 2626 Cyto 1 1279 Seq. ID No. 2631 Seq. ID No. 2632 Cyto 0 1281 Seq. ID No. 2633 Seq. ID No. 2634 Cyto 0 1283a Seq. ID No. 2635 Seq. ID No. 2636 Cyto 1283b Seq. ID No. 2637 Seq. ID No. 2638 Cyto 1283c Seq. ID No. 2639 Seq. ID No. 2640 Cyto 1284 Seq. ID No. 2641 Seq. ID No. 2642 Cyto 1285a Seq. ID No. 2643 Seq. ID No. 2644 Cyto 0 1285b Seq. ID No. 2645 Seq. ID No. 2646 Cyto 0 1287a Seq. ID No. 2647 Seq. ID No. 2648 Cyto 1287b Seq. ID No. 2649 Seq. ID No. 2650 Cyto 1289 Seq. ID No. 2653 Seq. ID No. 2654 IM 1 1290 Seq. ID No. 2655 Seq. ID No. 2656 Cyto 1293a Seq. ID No. 2657 Seq. ID No. 2658 Cyto 1293b Seq. ID No. 2659 Seq. ID No. 2660 Cyto 1294a Seq. ID No. 2661 Seq. ID No. 2662 Cyto 1295 Seq. ID No. 2663 Seq. ID No. 2664 Cyto 1297a Seq. ID No. 2665 Seq. ID No. 2666 Cyto 1297b Seq. ID No. 2667 Seq. ID No. 2668 Cyto 1300 Seq. ID No. 2669 Seq. ID No. 2670 Cyto 1302 Seq. ID No. 2671 Seq. ID No. 2672 Cyto 1305a Seq. ID No. 2673 Seq. ID No. 2674 Cyto 1305b Seq. ID No. 2675 Seq. ID No. 2676 Cyto 1305c Seq. ID No. 2677 Seq. ID No. 2678 Cyto 1308d Seq. ID No. 2685 Seq. ID No. 2686 IM 4 1308e Seq. ID No. 2687 Seq. ID No. 2688 IM 4 1311 Seq. ID No. 2689 Seq. ID No. 2690 Cyto 1320c Seq. ID No. 2709 Seq. ID No. 2710 IM 5 1321 Seq. ID No. 2711 Seq. ID No. 2712 Cyto 1322a Seq. ID No. 2713 Seq. ID No. 2714 Cyto 1322b Seq. ID No. 2715 Seq. ID No. 2716 Cyto 1324 Seq. ID No. 2719 Seq. ID No. 2720 Cyto 1326a Seq. ID No. 2721 Seq. ID No. 2722 Cyto 1326b Seq. ID No. 2723 Seq. ID No. 2724 Cyto 1326c Seq. ID No. 2725 Seq. ID No. 2726 Cyto 1333 Seq. ID No. 2727 Seq. ID No. 2728 Cyto 0 1335b Seq. ID No. 2735 Seq. ID No. 2736 IM 3 1337 Seq. ID No. 2737 Seq. ID No. 2738 Cyto 1338 Seq. ID No. 2739 Seq. ID No. 2740 IM 1 1340a Seq. ID No. 2741 Seq. ID No. 2742 IM 1 1340b Seq. ID No. 2743 Seq. ID No. 2744 IM 1 1341a Seq. ID No. 2745 Seq. ID No. 2746 IM 3 1341c Seq. ID No. 2747 Seq. ID No. 2748 IM 4 1344a Seq. ID No. 2749 Seq. ID No. 2750 Cyto 0 1344b Seq. ID No. 2751 Seq. ID No. 2752 Cyto 0 1348 Seq. ID No. 2753 Seq. ID No. 2754 IM 5 1349a Seq. ID No. 2755 Seq. ID No. 2756 IM 1 1349b Seq. ID No. 2757 Seq. ID No. 2758 IM 1 1349c Seq. ID No. 2759 Seq. ID No. 2760 IM 1 1350a Seq. ID No. 2761 Seq. ID No. 2762 Cyto 1350b Seq. ID No. 2763 Seq. ID No. 2764 Cyto 1353 Seq. ID No. 2765 Seq. ID No. 2766 Cyto 2 1355 Seq. ID No. 2767 Seq. ID No. 2768 Cyto 1358a Seq. ID No. 2769 Seq. ID No. 2770 Cyto 0 1358b Seq. ID No. 2771 Seq. ID No. 2772 Cyto 0 1359 Seq. ID No. 2773 Seq. ID No. 2774 Cyto 1 1361 Seq. ID No. 2775 Seq. ID No. 2776 Cyto 1364a Seq. ID No. 2777 Seq. ID No. 2778 Cyto 1364b Seq. ID No. 2779 Seq. ID No. 2780 Cyto 1364c Seq. ID No. 2781 Seq. ID No. 2782 Cyto 1366b Seq. ID No. 2787 Seq. ID No. 2788 IM 1 1367 Seq. ID No. 2789 Seq. ID No. 2790 Cyto 1 1368 Seq. ID No. 2791 Seq. ID No. 2792 Cyto 0 1371 Seq. ID No. 2793 Seq. ID No. 2794 Cyto 1373a Seq. ID No. 2795 Seq. ID No. 2796 Cyto 1373b Seq. ID No. 2797 Seq. ID No. 2798 Cyto 1374 Seq. ID No. 2799 Seq. ID No. 2800 IM 1377 Seq. ID No. 2803 Seq. ID No. 2804 IM 0 1378 Seq. ID No. 2805 Seq. ID No. 2806 IM 0 1379 Seq. ID No. 2807 Seq. ID No. 2808 IM 1 1381a Seq. ID No. 2811 Seq. ID No. 2812 IM 1 1383 Seq. ID No. 2817 Seq. ID No. 2818 Cyto 1386a Seq. ID No. 2825 Seq. ID No. 2826 IM 1 1386b Seq. ID No. 2827 Seq. ID No. 2828 IM 1 1387a Seq. ID No. 2829 Seq. ID No. 2830 OM 1 1394 Seq. ID No. 2843 Seq. ID No. 2844 Cyto 1 1396 Seq. ID No. 2847 Seq. ID No. 2848 Cyto 1397 Seq. ID No. 2849 Seq. ID No. 2850 Peri 1398 Seq. ID No. 2851 Seq. ID No. 2852 Cyto 1400 Seq. ID No. 2857 Seq. ID No. 2858 IM 1 1405 Seq. ID No. 2863 Seq. ID No. 2864 IM 2 1407b Seq. ID No. 2865 Seq. ID No. 2866 IM 1 1408 Seq. ID No. 2867 Seq. ID No. 2868 IM 5 1409 Seq. ID No. 2869 Seq. ID No. 2870 IM 1 1410 Seq. ID No. 2871 Seq. ID No. 2872 Cyto 1411b Seq. ID No. 2875 Seq. ID No. 2876 IM 4 1411c Seq. ID No. 2877 Seq. ID No. 2878 IM 6 1412a Seq. ID No. 2879 Seq. ID No. 2880 IM 8 1414a Seq. ID No. 2883 Seq. ID No. 2884 IM 0 1414b Seq. ID No. 2885 Seq. ID No. 2886 IM 0 1414c Seq. ID No. 2887 Seq. ID No. 2888 IM 0 1415 Seq. ID No. 2889 Seq. ID No. 2890 Cyto 1416 Seq. ID No. 2891 Seq. ID No. 2892 Cyto 1419 Seq. ID No. 2895 Seq. ID No. 2896 IM 1420a Seq. ID No. 2897 Seq. ID No. 2898 IM 0 1420b Seq. ID No. 2899 Seq. ID No. 2900 IM 0 1422 Seq. ID No. 2901 Seq. ID No. 2902 Cyto 0 1423 Seq. ID No. 2903 Seq. ID No. 2904 Cyto 1426b Seq. ID No. 2907 Seq. ID No. 2908 IM 6 1427a Seq. ID No. 2909 Seq. ID No. 2910 Cyto 1427b Seq. ID No. 2911 Seq. ID No. 2912 Cyto 1428 Seq. ID No. 2913 Seq. ID No. 2914 Cyto 1429a Seq. ID No. 2915 Seq. ID No. 2916 Cyto 1429b Seq. ID No. 2917 Seq. ID No. 2918 IM 1431 Seq. ID No. 2919 Seq. ID No. 2920 Cyto 0 1432 Seq. ID No. 2921 Seq. ID No. 2922 Cyto 0 1433 Seq. ID No. 2923 Seq. ID No. 2924 Cyto 0 1434a Seq. ID No. 2925 Seq. ID No. 2926 Cyto 1 1434b Seq. ID No. 2927 Seq. ID No. 2928 Cyto 1 1437a Seq. ID No. 2929 Seq. ID No. 2930 Cyto 0 1437b Seq. ID No. 2931 Seq. ID No. 2932 Cyto 0 1437c Seq. ID No. 2933 Seq. ID No. 2934 Cyto 0 1439d Seq. ID No. 2943 Seq. ID No. 2944 IM 7 1439e Seq. ID No. 2945 Seq. ID No. 2946 IM 7 1440d Seq. ID No. 2953 Seq. ID No. 2954 IM 12 1442a Seq. ID No. 2955 Seq. ID No. 2956 Cyto 1442b Seq. ID No. 2957 Seq. ID No. 2958 Cyto 1445a Seq. ID No. 2959 Seq. ID No. 2960 Cyto 1445b Seq. ID No. 2961 Seq. ID No. 2962 Cyto 1445c Seq. ID No. 2963 Seq. ID No. 2964 Cyto 1446a Seq. ID No. 2965 Seq. ID No. 2966 IM 2 1446b Seq. ID No. 2967 Seq. ID No. 2968 IM 2 1447b Seq. ID No. 2971 Seq. ID No. 2972 IM 11 1451 Seq. ID No. 2979 Seq. ID No. 2980 Cyto 1453 Seq. ID No. 2985 Seq. ID No. 2986 IM 5 1455a Seq. ID No. 2989 Seq. ID No. 2990 Cyto 1456 Seq. ID No. 2993 Seq. ID No. 2994 Cyto 1457c Seq. ID No. 2999 Seq. ID No. 3000 IM 8 1459 Seq. ID No. 3001 Seq. ID No. 3002 IM 1 1462a Seq. ID No. 3003 Seq. ID No. 3004 IM 5 1466b Seq. ID No. 3015 Seq. ID No. 3016 IM 2 1466c Seq. ID No. 3017 Seq. ID No. 3018 IM 2 1466d Seq. ID No. 3019 Seq. ID No. 3020 IM 2 1467 Seq. ID No. 3021 Seq. ID No. 3022 Cyto 2 1470c Seq. ID No. 3033 Seq. ID No. 3034 IM 8 1471 Seq. ID No. 3035 Seq. ID No. 3036 IM 6 1472b Seq. ID No. 3037 Seq. ID No. 3038 IM 1472c Seq. ID No. 3039 Seq. ID No. 3040 Cyto 1474 Seq. ID No. 3041 Seq. ID No. 3042 Cyto 1476 Seq. ID No. 3045 Seq. ID No. 3046 IM 5 1477a Seq. ID No. 3047 Seq. ID No. 3048 Cyto 0 1477b Seq. ID No. 3049 Seq. ID No. 3050 Cyto 0 1479a Seq. ID No. 3051 Seq. ID No. 3052 Cyto 1479b Seq. ID No. 3053 Seq. ID No. 3054 Cyto 1482a Seq. ID No. 3057 Seq. ID No. 3058 Cyto 0 1482b Seq. ID No. 3059 Seq. ID No. 3060 Cyto 0 1483 Seq. ID No. 3061 Seq. ID No. 3062 Cyto 1484b Seq. ID No. 3065 Seq. ID No. 3066 IM 4 1484c Seq. ID No. 3067 Seq. ID No. 3068 IM 4 1486 Seq. ID No. 3069 Seq. ID No. 3070 Cyto 1488d Seq. ID No. 3079 Seq. ID No. 3080 IM 4 1488e Seq. ID No. 3081 Seq. ID No. 3082 IM 4 1488f Seq. ID No. 3083 Seq. ID No. 3084 IM 4 1488g Seq. ID No. 3085 Seq. ID No. 3086 IM 4 1489 Seq. ID No. 3087 Seq. ID No. 3088 Cyto 1490 Seq. ID No. 3089 Seq. ID No. 3090 Cyto 1494 Seq. ID No. 3091 Seq. ID No. 3092 Cyto 1497 Seq. ID No. 3093 Seq. ID No. 3094 Cyto 0 1498a Seq. ID No. 3095 Seq. ID No. 3096 Cyto 1498b Seq. ID No. 3097 Seq. ID No. 3098 Cyto 1498c Seq. ID No. 3099 Seq. ID No. 3100 Cyto 1498d Seq. ID No. 3101 Seq. ID No. 3102 Cyto 1499 Seq. ID No. 3103 Seq. ID No. 3104 Cyto 1502a Seq. ID No. 3105 Seq. ID No. 3106 Cyto 1502b Seq. ID No. 3107 Seq. ID No. 3108 Cyto 1503a Seq. ID No. 3109 Seq. ID No. 3110 IM 4 1503b Seq. ID No. 3111 Seq. ID No. 3112 IM 4 1506a Seq. ID No. 3113 Seq. ID No. 3114 Cyto 0 1506b Seq. ID No. 3115 Seq. ID No. 3116 Cyto 0 1506c Seq. ID No. 3117 Seq. ID No. 3118 Cyto 0 1508 Seq. ID No. 3125 Seq. ID No. 3126 Cyto 0 1510a Seq. ID No. 3127 Seq. ID No. 3128 IM 0 1510b Seq. ID No. 3129 Seq. ID No. 3130 IM 0 1510c Seq. ID No. 3131 Seq. ID No. 3132 IM 0 1510d Seq. ID No. 3133 Seq. ID No. 3134 IM 0 1511 Seq. ID No. 3135 Seq. ID No. 3136 IM 0 1512 Seq. ID No. 3137 Seq. ID No. 3138 Cyto 1513a Seq. ID No. 3139 Seq. ID No. 3140 Cyto 1513b Seq. ID No. 3141 Seq. ID No. 3142 Cyto 1516 Seq. ID No. 3143 Seq. ID No. 3144 Cyto 1517b Seq. ID No. 3147 Seq. ID No. 3148 IM 3 1517c Seq. ID No. 3149 Seq. ID No. 3150 IM 3 1518a Seq. ID No. 3151 Seq. ID No. 3152 Cyto 0 1518b Seq. ID No. 3153 Seq. ID No. 3154 Cyto 0 1523 Seq. ID No. 3159 Seq. ID No. 3160 Cyto 0 1528 Seq. ID No. 3161 Seq. ID No. 3162 Cyto 1533a Seq. ID No. 3167 Seq. ID No. 3168 IM 0 1534a Seq. ID No. 3169 Seq. ID No. 3170 Cyto 0 1534b Seq. ID No. 3171 Seq. ID No. 3172 Cyto 0 1536a Seq. ID No. 3175 Seq. ID No. 3176 Cyto 1536b Seq. ID No. 3177 Seq. ID No. 3178 Cyto 0 1537 Seq. ID No. 3179 Seq. ID No. 3180 Cyto 1542 Seq. ID No. 3181 Seq. ID No. 3182 IM 0 1544 Seq. ID No. 3185 Seq. ID No. 3186 Cyto 1 1547a Seq. ID No. 3187 Seq. ID No. 3188 Cyto 1547b Seq. ID No. 3189 Seq. ID No. 3190 Cyto 1548 Seq. ID No. 3191 Seq. ID No. 3192 Cyto 1553a Seq. ID No. 3195 Seq. ID No. 3196 Cyto 1553b Seq. ID No. 3197 Seq. ID No. 3198 Cyto 1554a Seq. ID No. 3199 Seq. ID No. 3200 IM 1 1554c Seq. ID No. 3203 Seq. ID No. 3204 IM 3 1555 Seq. ID No. 3205 Seq. ID No. 3206 IM 1 1556a Seq. ID No. 3207 Seq. ID No. 3208 Cyto 1556b Seq. ID No. 3209 Seq. ID No. 3210 Cyto 1556c Seq. ID No. 3211 Seq. ID No. 3212 Cyto 1559b Seq. ID No. 3221 Seq. ID No. 3222 IM 7 1563 Seq. ID No. 3223 Seq. ID No. 3224 Cyto 1564a Seq. ID No. 3225 Seq. ID No. 3226 Cyto 1 1564b Seq. ID No. 3227 Seq. ID No. 3228 Cyto 1 1565 Seq. ID No. 3229 Seq. ID No. 3230 Cyto 1567 Seq. ID No. 3231 Seq. ID No. 3232 Cyto 1568b Seq. ID No. 3233 Seq. ID No. 3234 IM 1 1569 Seq. ID No. 3235 Seq. ID No. 3236 IM 2 1570 Seq. ID No. 3237 Seq. ID No. 3238 Peri 2 1571 Seq. ID No. 3239 Seq. ID No. 3240 IM 5 1572d Seq. ID No. 3247 Seq. ID No. 3248 IM 11 1573 Seq. ID No. 3251 Seq. ID No. 3252 Cyto 1576 Seq. ID No. 3253 Seq. ID No. 3254 Cyto 1578 Seq. ID No. 3259 Seq. ID No. 3260 IM 2 1581 Seq. ID No. 3265 Seq. ID No. 3266 IM 1 1582a Seq. ID No. 3267 Seq. ID No. 3268 IM 1582c Seq. ID No. 3271 Seq. ID No. 3272 IM 1 1584 Seq. ID No. 3273 Seq. ID No. 3274 Peri 1 1587a Seq. ID No. 3279 Seq. ID No. 3280 Cyto 1587b Seq. ID No. 3281 Seq. ID No. 3282 Cyto 1587c Seq. ID No. 3283 Seq. ID No. 3284 Cyto 1588 Seq. ID No. 3285 Seq. ID No. 3286 IM 0 1590 Seq. ID No. 3287 Seq. ID No. 3288 Cyto 1591 Seq. ID No. 3289 Seq. ID No. 3290 Cyto 1592a Seq. ID No. 3291 Seq. ID No. 3292 Cyto 1592b Seq. ID No. 3293 Seq. ID No. 3294 Cyto 1593 Seq. ID No. 3295 Seq. ID No. 3296 Cyto 1594b Seq. ID No. 3299 Seq. ID No. 3300 IM 1 1595a Seq. ID No. 3301 Seq. ID No. 3302 Cyto 0 1595b Seq. ID No. 3303 Seq. ID No. 3304 Cyto 0 1598a Seq. ID No. 3305 Seq. ID No. 3306 Cyto 0 1598b Seq. ID No. 3307 Seq. ID No. 3308 Cyto 0 1600a Seq. ID No. 3309 Seq. ID No. 3310 Cyto 1 1600b Seq. ID No. 3311 Seq. ID No. 3312 Cyto 1 1600c Seq. ID No. 3313 Seq. ID No. 3314 Cyto 1 1602 Seq. ID No. 3315 Seq. ID No. 3316 Cyto 1606b Seq. ID No. 3319 Seq. ID No. 3320 IM 2 1607a Seq. ID No. 3321 Seq. ID No. 3322 IM 5 1610a Seq. ID No. 3327 Seq. ID No. 3328 Cyto 1610b Seq. ID No. 3329 Seq. ID No. 3330 Cyto 1616a Seq. ID No. 3333 Seq. ID No. 3334 IM 1 1622a Seq. ID No. 3341 Seq. ID No. 3342 Cyto 0 1623a Seq. ID No. 3343 Seq. ID No. 3344 Cyto 1623b Seq. ID No. 3345 Seq. ID No. 3346 Cyto 1623c Seq. ID No. 3347 Seq. ID No. 3348 Cyto 1628a Seq. ID No. 3361 Seq. ID No. 3362 Cyto 1628b Seq. ID No. 3363 Seq. ID No. 3364 Cyto 1632a Seq. ID No. 3365 Seq. ID No. 3366 Cyto 0 1632b Seq. ID No. 3367 Seq. ID No. 3368 Cyto 0 1633a Seq. ID No. 3369 Seq. ID No. 3370 IM 2 1633b Seq. ID No. 3371 Seq. ID No. 3372 IM 2 1634a Seq. ID No. 3373 Seq. ID No. 3374 Cyto 1639b Seq. ID No. 3379 Seq. ID No. 3380 Cyto 1642a Seq. ID No. 3381 Seq. ID No. 3382 Cyto 1 1642b Seq. ID No. 3383 Seq. ID No. 3384 Cyto 1 1643a Seq. ID No. 3385 Seq. ID No. 3386 Cyto 1643b Seq. ID No. 3387 Seq. ID No. 3388 Cyto 1646c Seq. ID No. 3393 Seq. ID No. 3394 IM 11 1646e Seq. ID No. 3397 Seq. ID No. 3398 IM 13 1646f Seq. ID No. 3399 Seq. ID No. 3400 IM 13 1647 Seq. ID No. 3401 Seq. ID No. 3402 Cyto 1648b Seq. ID No. 3403 Seq. ID No. 3404 IM 3 1649b Seq. ID No. 3407 Seq. ID No. 3408 Cyto 2 1649c Seq. ID No. 3409 Seq. ID No. 3410 Cyto 2 1652a Seq. ID No. 3411 Seq. ID No. 3412 Cyto 1652b Seq. ID No. 3413 Seq. ID No. 3414 Cyto 1656b Seq. ID No. 3417 Seq. ID No. 3418 Cyto 1657 Seq. ID No. 3419 Seq. ID No. 3420 Cyto 1659b Seq. ID No. 3423 Seq. ID No. 3424 IM 9 1662a Seq. ID No. 3429 Seq. ID No. 3430 Cyto 1 1662b Seq. ID No. 3431 Seq. ID No. 3432 Cyto 1 1664 Seq. ID No. 3435 Seq. ID No. 3436 IM 0 1665a Seq. ID No. 3437 Seq. ID No. 3438 Cyto 1 1668 Seq. ID No. 3439 Seq. ID No. 3440 IM 1 1670a Seq. ID No. 3443 Seq. ID No. 3444 Cyto 1670b Seq. ID No. 3445 Seq. ID No. 3446 Cyto 1670c Seq. ID No. 3447 Seq. ID No. 3448 IM 1673f Seq. ID No. 3459 Seq. ID No. 3460 IM 14 1674 Seq. ID No. 3461 Seq. ID No. 3462 OM 1 1675b Seq. ID No. 3465 Seq. ID No. 3466 Cyto 1 1675c Seq. ID No. 3467 Seq. ID No. 3468 Cyto 1 1676 Seq. ID No. 3469 Seq. ID No. 3470 Cyto 1 1677 Seq. ID No. 3471 Seq. ID No. 3472 Cyto 0 1679 Seq. ID No. 3473 Seq. ID No. 3474 IM 1 1680 Seq. ID No. 3475 Seq. ID No. 3476 IM 1682a Seq. ID No. 3477 Seq. ID No. 3478 Cyto 1682b Seq. ID No. 3479 Seq. ID No. 3480 Cyto 1683b Seq. ID No. 3483 Seq. ID No. 3484 IM 6 1684 Seq. ID No. 3485 Seq. ID No. 3486 Cyto 1685 Seq. ID No. 3487 Seq. ID No. 3488 Cyto 0 1687 Seq. ID No. 3489 Seq. ID No. 3490 Cyto 0 1688c Seq. ID No. 3495 Seq. ID No. 3496 IM 11 1689a Seq. ID No. 3497 Seq. ID No. 3498 IM 1689b Seq. ID No. 3499 Seq. ID No. 3500 IM 1689c Seq. ID No. 3501 Seq. ID No. 3502 Cyto 1691 Seq. ID No. 3507 Seq. ID No. 3508 IM 9 1692 Seq. ID No. 3509 Seq. ID No. 3510 Cyto 1693 Seq. ID No. 3511 Seq. ID No. 3512 IM 1694a Seq. ID No. 3513 Seq. ID No. 3514 Cyto 1694b Seq. ID No. 3515 Seq. ID No. 3516 Cyto 1696 Seq. ID No. 3521 Seq. ID No. 3522 Peri 1 1697a Seq. ID No. 3523 Seq. ID No. 3524 IM 7 1697b Seq. ID No. 3525 Seq. ID No. 3526 IM 9 1699b Seq. ID No. 3529 Seq. ID No. 3530 IM 10 1700b Seq. ID No. 3533 Seq. ID No. 3534 IM 4 1701a Seq. ID No. 3535 Seq. ID No. 3536 Cyto 0 1701b Seq. ID No. 3537 Seq. ID No. 3538 Cyto 0 1704a Seq. ID No. 3541 Seq. ID No. 3542 IM 0 1704b Seq. ID No. 3543 Seq. ID No. 3544 Cyto 0 1705a Seq. ID No. 3545 Seq. ID No. 3546 Cyto 1705b Seq. ID No. 3547 Seq. ID No. 3548 Cyto 1706 Seq. ID No. 3549 Seq. ID No. 3550 Cyto 1707a Seq. ID No. 3551 Seq. ID No. 3552 Cyto 1707b Seq. ID No. 3553 Seq. ID No. 3554 Cyto 1708 Seq. ID No. 3555 Seq. ID No. 3556 Cyto 0 1709 Seq. ID No. 3557 Seq. ID No. 3558 Cyto 1710a Seq. ID No. 3559 Seq. ID No. 3560 Peri 1712a Seq. ID No. 3563 Seq. ID No. 3564 Cyto 1712b Seq. ID No. 3565 Seq. ID No. 3566 Cyto 1715a Seq. ID No. 3567 Seq. ID No. 3568 Cyto 1715b Seq. ID No. 3569 Seq. ID No. 3570 Cyto 1718a Seq. ID No. 3571 Seq. ID No. 3572 Cyto 1722 Seq. ID No. 3575 Seq. ID No. 3576 IM 1 1723a Seq. ID No. 3577 Seq. ID No. 3578 Cyto 0 1723b Seq. ID No. 3579 Seq. ID No. 3580 Cyto 0 1727 Seq. ID No. 3583 Seq. ID No. 3584 Cyto 0 1728 Seq. ID No. 3585 Seq. ID No. 3586 Cyto 1733 Seq. ID No. 3589 Seq. ID No. 3590 Cyto 1734 Seq. ID No. 3591 Seq. ID No. 3592 Cyto 1737a Seq. ID No. 3597 Seq. ID No. 3598 Cyto 1737b Seq. ID No. 3599 Seq. ID No. 3600 Cyto 1738a Seq. ID No. 3601 Seq. ID No. 3602 Cyto 1738b Seq. ID No. 3603 Seq. ID No. 3604 Cyto 0 1738c Seq. ID No. 3605 Seq. ID No. 3606 Cyto 0 1739 Seq. ID No. 3607 Seq. ID No. 3608 Cyto 1741 Seq. ID No. 3609 Seq. ID No. 3610 Cyto 1744a Seq. ID No. 3613 Seq. ID No. 3614 Cyto 1744b Seq. ID No. 3615 Seq. ID No. 3616 Cyto 1749b Seq. ID No. 3623 Seq. ID No. 3624 IM 4 1752a Seq. ID No. 3627 Seq. ID No. 3628 Cyto 1753 Seq. ID No. 3631 Seq. ID No. 3632 Cyto 1756a Seq. ID No. 3633 Seq. ID No. 3634 Cyto 1757a Seq. ID No. 3637 Seq. ID No. 3638 IM 2 1757b Seq. ID No. 3639 Seq. ID No. 3640 IM 2 1759 Seq. ID No. 3641 Seq. ID No. 3642 Cyto 1760 Seq. ID No. 3643 Seq. ID No. 3644 Cyto 1762 Seq. ID No. 3645 Seq. ID No. 3646 Cyto 1764a Seq. ID No. 3647 Seq. ID No. 3648 IM 1764b Seq. ID No. 3649 Seq. ID No. 3650 IM 1764c Seq. ID No. 3651 Seq. ID No. 3652 IM 1765 Seq. ID No. 3653 Seq. ID No. 3654 Cyto 1766 Seq. ID No. 3655 Seq. ID No. 3656 IM 0 1767a Seq. ID No. 3657 Seq. ID No. 3658 Cyto 1767b Seq. ID No. 3659 Seq. ID No. 3660 Cyto 1769a Seq. ID No. 3661 Seq. ID No. 3662 IM 5 1769b Seq. ID No. 3663 Seq. ID No. 3664 IM 7 1771 Seq. ID No. 3665 Seq. ID No. 3666 Cyto 1773 Seq. ID No. 3667 Seq. ID No. 3668 Cyto 1774 Seq. ID No. 3669 Seq. ID No. 3670 IM 1775a Seq. ID No. 3671 Seq. ID No. 3672 Cyto 1775b Seq. ID No. 3673 Seq. ID No. 3674 Cyto 1775c Seq. ID No. 3675 Seq. ID No. 3676 Cyto 1780 Seq. ID No. 3681 Seq. ID No. 3682 IM 0 1783a Seq. ID No. 3683 Seq. ID No. 3684 IM 1 1783b Seq. ID No. 3685 Seq. ID No. 3686 IM 1 1784a Seq. ID No. 3687 Seq. ID No. 3688 IM 1788a Seq. ID No. 3691 Seq. ID No. 3692 Cyto 1788b Seq. ID No. 3693 Seq. ID No. 3694 IM 1788c Seq. ID No. 3695 Seq. ID No. 3696 Cyto 1789a Seq. ID No. 3697 Seq. ID No. 3698 Cyto 1789b Seq. ID No. 3699 Seq. ID No. 3700 Cyto 1790a Seq. ID No. 3701 Seq. ID No. 3702 Cyto 2 1790b Seq. ID No. 3703 Seq. ID No. 3704 Cyto 3 1792a Seq. ID No. 3705 Seq. ID No. 3706 Peri 0 1792b Seq. ID No. 3707 Seq. ID No. 3708 Cyto 0 1792c Seq. ID No. 3709 Seq. ID No. 3710 Cyto 0 1793a Seq. ID No. 3711 Seq. ID No. 3712 IM 1793b Seq. ID No. 3713 Seq. ID No. 3714 IM 1793c Seq. ID No. 3715 Seq. ID No. 3716 IM 1797a Seq. ID No. 3719 Seq. ID No. 3720 Cyto 1797b Seq. ID No. 3721 Seq. ID No. 3722 Cyto 1798b Seq. ID No. 3725 Seq. ID No. 3726 IM 4 1800 Seq. ID No. 3729 Seq. ID No. 3730 IM 1 1802a Seq. ID No. 3731 Seq. ID No. 3732 IM 2 1802b Seq. ID No. 3733 Seq. ID No. 3734 IM 2 1803 Seq. ID No. 3735 Seq. ID No. 3736 IM 3 1804a Seq. ID No. 3737 Seq. ID No. 3738 IM 2 1804b Seq. ID No. 3739 Seq. ID No. 3740 IM 2 1806a Seq. ID No. 3743 Seq. ID No. 3744 IM 5 1806c Seq. ID No. 3747 Seq. ID No. 3748 IM 5 1807a Seq. ID No. 3749 Seq. ID No. 3750 IM 2 1807b Seq. ID No. 3751 Seq. ID No. 3752 IM 2 1808d Seq. ID No. 3759 Seq. ID No. 3760 IM 15 1809d Seq. ID No. 3767 Seq. ID No. 3768 IM 12 1809e Seq. ID No. 3769 Seq. ID No. 3770 IM 14 1809f Seq. ID No. 3771 Seq. ID No. 3772 IM 14 1810a Seq. ID No. 3773 Seq. ID No. 3774 Cyto 1810b Seq. ID No. 3775 Seq. ID No. 3776 Cyto 1811a Seq. ID No. 3777 Seq. ID No. 3778 Cyto 1811b Seq. ID No. 3779 Seq. ID No. 3780 Cyto 1813 Seq. ID No. 3785 Seq. ID No. 3786 IM 1 1815a Seq. ID No. 3787 Seq. ID No. 3788 Cyto 1815b Seq. ID No. 3789 Seq. ID No. 3790 Cyto 1815c Seq. ID No. 3791 Seq. ID No. 3792 Cyto 1816b Seq. ID No. 3795 Seq. ID No. 3796 IM 1 1816c Seq. ID No. 3797 Seq. ID No. 3798 IM 1 1819a Seq. ID No. 3801 Seq. ID No. 3802 IM 0 1819b Seq. ID No. 3803 Seq. ID No. 3804 IM 0 1821 Seq. ID No. 3805 Seq. ID No. 3806 Cyto 0 1823a Seq. ID No. 3809 Seq. ID No. 3810 Cyto 1823b Seq. ID No. 3811 Seq. ID No. 3812 Cyto 1828 Seq. ID No. 3819 Seq. ID No. 3820 Cyto 1830a Seq. ID No. 3821 Seq. ID No. 3822 IM 6 1830b Seq. ID No. 3823 Seq. ID No. 3824 IM 7 1833 Seq. ID No. 3825 Seq. ID No. 3826 Cyto 1834 Seq. ID No. 3827 Seq. ID No. 3828 Cyto 1835 Seq. ID No. 3829 Seq. ID No. 3830 Cyto 1836a Seq. ID No. 3831 Seq. ID No. 3832 IM 1 1836b Seq. ID No. 3833 Seq. ID No. 3834 IM 1 1837 Seq. ID No. 3835 Seq. ID No. 3836 IM 1838c Seq. ID No. 3841 Seq. ID No. 3842 IM 6 1838d Seq. ID No. 3843 Seq. ID No. 3844 IM 6 1839a Seq. ID No. 3845 Seq. ID No. 3846 Cyto 0 1839b Seq. ID No. 3847 Seq. ID No. 3848 Cyto 0 1842d Seq. ID No. 3855 Seq. ID No. 3856 IM 10 1843 Seq. ID No. 3857 Seq. ID No. 3858 Cyto 1848b Seq. ID No. 3867 Seq. ID No. 3868 IM 10 1850a Seq. ID No. 3869 Seq. ID No. 3870 IM 1 1850b Seq. ID No. 3871 Seq. ID No. 3872 IM 1 1850c Seq. ID No. 3873 Seq. ID No. 3874 IM 1 1853a Seq. ID No. 3875 Seq. ID No. 3876 IM 0 1853b Seq. ID No. 3877 Seq. ID No. 3878 IM 0 1854b Seq. ID No. 3881 Seq. ID No. 3882 IM 4 1855 Seq. ID No. 3883 Seq. ID No. 3884 IM 1 1856 Seq. ID No. 3885 Seq. ID No. 3886 Cyto 1857a Seq. ID No. 3887 Seq. ID No. 3888 Cyto 0 1857d Seq. ID No. 3893 Seq. ID No. 3894 IM 8 1859 Seq. ID No. 3897 Seq. ID No. 3898 Cyto 1861a Seq. ID No. 3899 Seq. ID No. 3900 Cyto 1861b Seq. ID No. 3901 Seq. ID No. 3902 Cyto 1863a Seq. ID No. 3905 Seq. ID No. 3906 Cyto 1863b Seq. ID No. 3907 Seq. ID No. 3908 Cyto 0 1864a Seq. ID No. 3909 Seq. ID No. 3910 Cyto 0 1865a Seq. ID No. 3911 Seq. ID No. 3912 IM 6 1865b Seq. ID No. 3913 Seq. ID No. 3914 IM 7 1869 Seq. ID No. 3917 Seq. ID No. 3918 Cyto 1870 Seq. ID No. 3919 Seq. ID No. 3920 Cyto 0 1873a Seq. ID No. 3921 Seq. ID No. 3922 Cyto 1875b Seq. ID No. 3927 Seq. ID No. 3928 Cyto 1875c Seq. ID No. 3929 Seq. ID No. 3930 IM 1 1877a Seq. ID No. 3931 Seq. ID No. 3932 Cyto 1877b Seq. ID No. 3933 Seq. ID No. 3934 Cyto 1878 Seq. ID No. 3935 Seq. ID No. 3936 IM 1879 Seq. ID No. 3937 Seq. ID No. 3938 Cyto 1 1882 Seq. ID No. 3939 Seq. ID No. 3940 IM 2 1884 Seq. ID No. 3941 Seq. ID No. 3942 Cyto 1886 Seq. ID No. 3943 Seq. ID No. 3944 Cyto 1887 Seq. ID No. 3945 Seq. ID No. 3946 Cyto 0 1888a Seq. ID No. 3947 Seq. ID No. 3948 IM 10 1888b Seq. ID No. 3949 Seq. ID No. 3950 IM 10 1890 Seq. ID No. 3951 Seq. ID No. 3952 Cyto 1891a Seq. ID No. 3953 Seq. ID No. 3954 Cyto 1891b Seq. ID No. 3955 Seq. ID No. 3956 Cyto 1893 Seq. ID No. 3957 Seq. ID No. 3958 Cyto 0 1895 Seq. ID No. 3961 Seq. ID No. 3962 IM 0 1896b Seq. ID No. 3965 Seq. ID No. 3966 IM 2 1897a Seq. ID No. 3967 Seq. ID No. 3968 Cyto 1897b Seq. ID No. 3969 Seq. ID No. 3970 Cyto 1897c Seq. ID No. 3971 Seq. ID No. 3972 Cyto 1899 Seq. ID No. 3977 Seq. ID No. 3978 Cyto 1900 Seq. ID No. 3979 Seq. ID No. 3980 Cyto 1 1902a Seq. ID No. 3981 Seq. ID No. 3982 Cyto 0 1902b Seq. ID No. 3983 Seq. ID No. 3984 Cyto 0 1907 Seq. ID No. 3985 Seq. ID No. 3986 Cyto 1912 Seq. ID No. 3987 Seq. ID No. 3988 Cyto 0 1915a Seq. ID No. 3989 Seq. ID No. 3990 Cyto 1915b Seq. ID No. 3991 Seq. ID No. 3992 Cyto 1918b Seq. ID No. 3999 Seq. ID No. 4000 IM 0 1918c Seq. ID No. 4001 Seq. ID No. 4002 IM 0 1918d Seq. ID No. 4003 Seq. ID No. 4004 IM 0 1923a Seq. ID No. 4011 Seq. ID No. 4012 Cyto 0 1923b Seq. ID No. 4013 Seq. ID No. 4014 Cyto 0 1925 Seq. ID No. 4015 Seq. ID No. 4016 Cyto 1926 Seq. ID No. 4017 Seq. ID No. 4018 Cyto 1 1927a Seq. ID No. 4019 Seq. ID No. 4020 Cyto 1927b Seq. ID No. 4021 Seq. ID No. 4022 Cyto 0 1930 Seq. ID No. 4023 Seq. ID No. 4024 Cyto 1931c Seq. ID No. 4029 Seq. ID No. 4030 IM 7 1932 Seq. ID No. 4031 Seq. ID No. 4032 IM 3 1933a Seq. ID No. 4033 Seq. ID No. 4034 Cyto 1 1933b Seq. ID No. 4035 Seq. ID No. 4036 Cyto 1 1934 Seq. ID No. 4037 Seq. ID No. 4038 Cyto 1939a Seq. ID No. 4051 Seq. ID No. 4052 Cyto 0 1939b Seq. ID No. 4053 Seq. ID No. 4054 Cyto 0 1939c Seq. ID No. 4055 Seq. ID No. 4056 IM 0 1940 Seq. ID No. 4057 Seq. ID No. 4058 Cyto 1941a Seq. ID No. 4059 Seq. ID No. 4060 IM 2 1942 Seq. ID No. 4063 Seq. ID No. 4064 Cyto 1943a Seq. ID No. 4065 Seq. ID No. 4066 Cyto 0 1943b Seq. ID No. 4067 Seq. ID No. 4068 Cyto 0 1944 Seq. ID No. 4069 Seq. ID No. 4070 IM 1 1946c Seq. ID No. 4075 Seq. ID No. 4076 IM 10 1949 Seq. ID No. 4077 Seq. ID No. 4078 Cyto 1951c Seq. ID No. 4085 Seq. ID No. 4086 IM 4 1951d Seq. ID No. 4087 Seq. ID No. 4088 IM 4 1953 Seq. ID No. 4089 Seq. ID No. 4090 IM 1 1954a Seq. ID No. 4091 Seq. ID No. 4092 IM 0 1954b Seq. ID No. 4093 Seq. ID No. 4094 IM 0 1954c Seq. ID No. 4095 Seq. ID No. 4096 IM 0 1956 Seq. ID No. 4097 Seq. ID No. 4098 Cyto 1957 Seq. ID No. 4099 Seq. ID No. 4100 Cyto 1958c Seq. ID No. 4105 Seq. ID No. 4106 IM 9 1960a Seq. ID No. 4107 Seq. ID No. 4108 Cyto 0 1960b Seq. ID No. 4109 Seq. ID No. 4110 Cyto 0 1961 Seq. ID No. 4113 Seq. ID No. 4114 IM 1 1962a Seq. ID No. 4115 Seq. ID No. 4116 Cyto 1962b Seq. ID No. 4117 Seq. ID No. 4118 Cyto 1965a Seq. ID No. 4119 Seq. ID No. 4120 Cyto 0 1965b Seq. ID No. 4121 Seq. ID No. 4122 Cyto 0 1966 Seq. ID No. 4123 Seq. ID No. 4124 Cyto 1967 Seq. ID No. 4125 Seq. ID No. 4126 Cyto 1968 Seq. ID No. 4127 Seq. ID No. 4128 Cyto 1969 Seq. ID No. 4129 Seq. ID No. 4130 IM 3 1970a Seq. ID No. 4131 Seq. ID No. 4132 Cyto 1979a Seq. ID No. 4147 Seq. ID No. 4148 Cyto 1979b Seq. ID No. 4149 Seq. ID No. 4150 Cyto 1981 Seq. ID No. 4155 Seq. ID No. 4156 Cyto 1 1982 Seq. ID No. 4157 Seq. ID No. 4158 IM 1985a Seq. ID No. 4159 Seq. ID No. 4160 Cyto 1985b Seq. ID No. 4161 Seq. ID No. 4162 Cyto 1986 Seq. ID No. 4163 Seq. ID No. 4164 Cyto 1987a Seq. ID No. 4165 Seq. ID No. 4166 Cyto 1987b Seq. ID No. 4167 Seq. ID No. 4168 Cyto 1989a Seq. ID No. 4169 Seq. ID No. 4170 Cyto 1989b Seq. ID No. 4171 Seq. ID No. 4172 Cyto 1989c Seq. ID No. 4173 Seq. ID No. 4174 Cyto 1990a Seq. ID No. 4175 Seq. ID No. 4176 Cyto 1990b Seq. ID No. 4177 Seq. ID No. 4178 Cyto 1990c Seq. ID No. 4179 Seq. ID No. 4180 Cyto 1992a Seq. ID No. 4183 Seq. ID No. 4184 Cyto 1992b Seq. ID No. 4185 Seq. ID No. 4186 Cyto 1993a Seq. ID No. 4187 Seq. ID No. 4188 Cyto 1993b Seq. ID No. 4189 Seq. ID No. 4190 Cyto 1993c Seq. ID No. 4191 Seq. ID No. 4192 Cyto 1996 Seq. ID No. 4193 Seq. ID No. 4194 Cyto 0 2000 Seq. ID No. 4195 Seq. ID No. 4196 IM 2001 Seq. ID No. 4197 Seq. ID No. 4198 IM 0 2003 Seq. ID No. 4199 Seq. ID No. 4200 Cyto 2006 Seq. ID No. 4201 Seq. ID No. 4202 Cyto 2008 Seq. ID No. 4203 Seq. ID No. 4204 IM 2 2010 Seq. ID No. 4205 Seq. ID No. 4206 Cyto 2011a Seq. ID No. 4207 Seq. ID No. 4208 Cyto 1 2011b Seq. ID No. 4209 Seq. ID No. 4210 Cyto 1 2011c Seq. ID No. 4211 Seq. ID No. 4212 Cyto 1 2013a Seq. ID No. 4213 Seq. ID No. 4214 Cyto 2013b Seq. ID No. 4215 Seq. ID No. 4216 Cyto 2014c Seq. ID No. 4217 Seq. ID No. 4218 Cyto 2015 Seq. ID No. 4219 Seq. ID No. 4220 Cyto 2016e Seq. ID No. 4229 Seq. ID No. 4230 IM 12 2016h Seq. ID No. 4235 Seq. ID No. 4236 IM 13 2020 Seq. ID No. 4237 Seq. ID No. 4238 IM 1 2021 Seq. ID No. 4239 Seq. ID No. 4240 IM 2 2023b Seq. ID No. 4243 Seq. ID No. 4244 IM 7 2024a Seq. ID No. 4245 Seq. ID No. 4246 Cyto 1 2024c Seq. ID No. 4249 Seq. ID No. 4250 IM 2 2024d Seq. ID No. 4251 Seq. ID No. 4252 IM 2 2027 Seq. ID No. 4255 Seq. ID No. 4256 Cyto 0 2033 Seq. ID No. 4267 Seq. ID No. 4268 Cyto 2036 Seq. ID No. 4271 Seq. ID No. 4272 Cyto 2037 Seq. ID No. 4273 Seq. ID No. 4274 Cyto 2040a Seq. ID No. 4277 Seq. ID No. 4278 IM 3 2042 Seq. ID No. 4279 Seq. ID No. 4280 IM 2 2043b Seq. ID No. 4281 Seq. ID No. 4282 Cyto 2044 Seq. ID No. 4283 Seq. ID No. 4284 Cyto 0 2046a Seq. ID No. 4289 Seq. ID No. 4290 Cyto 2046b Seq. ID No. 4291 Seq. ID No. 4292 Cyto 2047a Seq. ID No. 4293 Seq. ID No. 4294 IM 0 2047b Seq. ID No. 4295 Seq. ID No. 4296 IM 0 2050 Seq. ID No. 4299 Seq. ID No. 4300 Cyto 2053 Seq. ID No. 4301 Seq. ID No. 4302 Peri 2054 Seq. ID No. 4303 Seq. ID No. 4304 Cyto 2055 Seq. ID No. 4305 Seq. ID No. 4306 Cyto 2057 Seq. ID No. 4309 Seq. ID No. 4310 IM 0 2060a Seq. ID No. 4315 Seq. ID No. 4316 Cyto 2060b Seq. ID No. 4317 Seq. ID No. 4318 Cyto 2062a Seq. ID No. 4319 Seq. ID No. 4320 Cyto 0 2062b Seq. ID No. 4321 Seq. ID No. 4322 Cyto 0 2062c Seq. ID No. 4323 Seq. ID No. 4324 Cyto 0 2064 Seq. ID No. 4325 Seq. ID No. 4326 Cyto 2065a Seq. ID No. 4327 Seq. ID No. 4328 Cyto 2065b Seq. ID No. 4329 Seq. ID No. 4330 Cyto 2066 Seq. ID No. 4331 Seq. ID No. 4332 IM 2068 Seq. ID No. 4333 Seq. ID No. 4334 Cyto 2069a Seq. ID No. 4335 Seq. ID No. 4336 Cyto 2069b Seq. ID No. 4337 Seq. ID No. 4338 Cyto 2069c Seq. ID No. 4339 Seq. ID No. 4340 Cyto 2074a Seq. ID No. 4341 Seq. ID No. 4342 Cyto 2075a Seq. ID No. 4345 Seq. ID No. 4346 Cyto 2075b Seq. ID No. 4347 Seq. ID No. 4348 Cyto 2076a Seq. ID No. 4349 Seq. ID No. 4350 Cyto 2076b Seq. ID No. 4351 Seq. ID No. 4352 IM 2076c Seq. ID No. 4353 Seq. ID No. 4354 IM 2078 Seq. ID No. 4355 Seq. ID No. 4356 IM 1 2079a Seq. ID No. 4357 Seq. ID No. 4358 IM 1 2079b Seq. ID No. 4359 Seq. ID No. 4360 IM 1 2079c Seq. ID No. 4361 Seq. ID No. 4362 IM 1 2081a Seq. ID No. 4363 Seq. ID No. 4364 Cyto 2081b Seq. ID No. 4365 Seq. ID No. 4366 Cyto 2086a Seq. ID No. 4367 Seq. ID No. 4368 Cyto 2086b Seq. ID No. 4369 Seq. ID No. 4370 Cyto 2087a Seq. ID No. 4371 Seq. ID No. 4372 Cyto 2087b Seq. ID No. 4373 Seq. ID No. 4374 Cyto 2088 Seq. ID No. 4375 Seq. ID No. 4376 IM 1 2091 Seq. ID No. 4377 Seq. ID No. 4378 Cyto 2093a Seq. ID No. 4381 Seq. ID No. 4382 Cyto 2094 Seq. ID No. 4383 Seq. ID No. 4384 Cyto 2096b Seq. ID No. 4387 Seq. ID No. 4388 IM 9 2097 Seq. ID No. 4393 Seq. ID No. 4394 Cyto 0 2098b Seq. ID No. 4395 Seq. ID No. 4396 IM 1 2100 Seq. ID No. 4397 Seq. ID No. 4398 Cyto 1 2104 Seq. ID No. 4401 Seq. ID No. 4402 IM 1 2107a Seq. ID No. 4405 Seq. ID No. 4406 Cyto 0 2107b Seq. ID No. 4407 Seq. ID No. 4408 Cyto 0 2109a Seq. ID No. 4409 Seq. ID No. 4410 Cyto 2109b Seq. ID No. 4411 Seq. ID No. 4412 Cyto 2110a Seq. ID No. 4413 Seq. ID No. 4414 Cyto 1 2110b Seq. ID No. 4415 Seq. ID No. 4416 Cyto 1 2110c Seq. ID No. 4417 Seq. ID No. 4418 Cyto 1 2112a Seq. ID No. 4419 Seq. ID No. 4420 Cyto 1 2112b Seq. ID No. 4421 Seq. ID No. 4422 Cyto 1 2112c Seq. ID No. 4423 Seq. ID No. 4424 IM 1 2114b Seq. ID No. 4425 Seq. ID No. 4426 IM 1 2115a Seq. ID No. 4427 Seq. ID No. 4428 Cyto 2115b Seq. ID No. 4429 Seq. ID No. 4430 Cyto 2115c Seq. ID No. 4431 Seq. ID No. 4432 IM 2116 Seq. ID No. 4433 Seq. ID No. 4434 Cyto 2117 Seq. ID No. 4435 Seq. ID No. 4436 Cyto 0 2123 Seq. ID No. 4443 Seq. ID No. 4444 Cyto 2124a Seq. ID No. 4445 Seq. ID No. 4446 Cyto 2124b Seq. ID No. 4447 Seq. ID No. 4448 Cyto 2125a Seq. ID No. 4449 Seq. ID No. 4450 Cyto 2125b Seq. ID No. 4451 Seq. ID No. 4452 Cyto 2127a Seq. ID No. 4453 Seq. ID No. 4454 IM 1 2127b Seq. ID No. 4455 Seq. ID No. 4456 IM 1 2128a Seq. ID No. 4457 Seq. ID No. 4458 Cyto 2128b Seq. ID No. 4459 Seq. ID No. 4460 Cyto 2133 Seq. ID No. 4461 Seq. ID No. 4462 Cyto 0 2138a Seq. ID No. 4463 Seq. ID No. 4464 Cyto 0 2138b Seq. ID No. 4465 Seq. ID No. 4466 Cyto 0 2138c Seq. ID No. 4467 Seq. ID No. 4468 Cyto 0 2140b Seq. ID No. 4471 Seq. ID No. 4472 IM 5 2142b Seq. ID No. 4475 Seq. ID No. 4476 IM 7 2144a Seq. ID No. 4477 Seq. ID No. 4478 Cyto 2144b Seq. ID No. 4479 Seq. ID No. 4480 Cyto 2147c Seq. ID No. 4487 Seq. ID No. 4488 IM 5 2149a Seq. ID No. 4489 Seq. ID No. 4490 Cyto 2149b Seq. ID No. 4491 Seq. ID No. 4492 Cyto 2152a Seq. ID No. 4499 Seq. ID No. 4500 Cyto 2153 Seq. ID No. 4501 Seq. ID No. 4502 Cyto 2155a Seq. ID No. 4503 Seq. ID No. 4504 Cyto 0 2155b Seq. ID No. 4505 Seq. ID No. 4506 Cyto 0 2156a Seq. ID No. 4507 Seq. ID No. 4508 Cyto 2156b Seq. ID No. 4509 Seq. ID No. 4510 Cyto 2156c Seq. ID No. 4511 Seq. ID No. 4512 Cyto 2160a Seq. ID No. 4517 Seq. ID No. 4518 Cyto 2160b Seq. ID No. 4519 Seq. ID No. 4520 Cyto 2160c Seq. ID No. 4521 Seq. ID No. 4522 Cyto 2160d Seq. ID No. 4523 Seq. ID No. 4524 Cyto 2161a Seq. ID No. 4525 Seq. ID No. 4526 Cyto 1 2164 Seq. ID No. 4531 Seq. ID No. 4532 IM 0 2166a Seq. ID No. 4535 Seq. ID No. 4536 Cyto 1 2166b Seq. ID No. 4537 Seq. ID No. 4538 Cyto 2 2169 Seq. ID No. 4539 Seq. ID No. 4540 Cyto 2171 Seq. ID No. 4541 Seq. ID No. 4542 Cyto 0 2172 Seq. ID No. 4543 Seq. ID No. 4544 Cyto 2173a Seq. ID No. 4545 Seq. ID No. 4546 Cyto 0 2173b Seq. ID No. 4547 Seq. ID No. 4548 Cyto 0 2174 Seq. ID No. 4549 Seq. ID No. 4550 IM 0 2175 Seq. ID No. 4551 Seq. ID No. 4552 IM 2 2176a Seq. ID No. 4553 Seq. ID No. 4554 Cyto 0 2176b Seq. ID No. 4555 Seq. ID No. 4556 IM 1 2176c Seq. ID No. 4557 Seq. ID No. 4558 Cyto 1 2176d Seq. ID No. 4559 Seq. ID No. 4560 Cyto 1 2177b Seq. ID No. 4561 Seq. ID No. 4562 IM 1 2179a Seq. ID No. 4563 Seq. ID No. 4564 Cyto 0 2179b Seq. ID No. 4565 Seq. ID No. 4566 Cyto 0 2180 Seq. ID No. 4567 Seq. ID No. 4568 Cyto 0 2181a Seq. ID No. 4569 Seq. ID No. 4570 Cyto 0 2181b Seq. ID No. 4571 Seq. ID No. 4572 Cyto 0 2182 Seq. ID No. 4573 Seq. ID No. 4574 IM 1 2183 Seq. ID No. 4575 Seq. ID No. 4576 Cyto 2185 Seq. ID No. 4577 Seq. ID No. 4578 Cyto 2186a Seq. ID No. 4579 Seq. ID No. 4580 Cyto 2186b Seq. ID No. 4581 Seq. ID No. 4582 Cyto 2189a Seq. ID No. 4583 Seq. ID No. 4584 Cyto 2189b Seq. ID No. 4585 Seq. ID No. 4586 Cyto 2193 Seq. ID No. 4591 Seq. ID No. 4592 Cyto 2194a Seq. ID No. 4593 Seq. ID No. 4594 Cyto 2194c Seq. ID No. 4595 Seq. ID No. 4596 Cyto 2196 Seq. ID No. 4597 Seq. ID No. 4598 Cyto 2197a Seq. ID No. 4599 Seq. ID No. 4600 Cyto 2197b Seq. ID No. 4601 Seq. ID No. 4602 Cyto 2197c Seq. ID No. 4603 Seq. ID No. 4604 Cyto 2201a Seq. ID No. 4605 Seq. ID No. 4606 Cyto 0 2201b Seq. ID No. 4607 Seq. ID No. 4608 Cyto 0 2203 Seq. ID No. 4609 Seq. ID No. 4610 Cyto 2204 Seq. ID No. 4611 Seq. ID No. 4612 Cyto 0 2206a Seq. ID No. 4613 Seq. ID No. 4614 Cyto 2206b Seq. ID No. 4615 Seq. ID No. 4616 Cyto 2208a Seq. ID No. 4617 Seq. ID No. 4618 Cyto 0 2208b Seq. ID No. 4619 Seq. ID No. 4620 Cyto 0 2208c Seq. ID No. 4621 Seq. ID No. 4622 Cyto 0 2209 Seq. ID No. 4623 Seq. ID No. 4624 Cyto 2212a Seq. ID No. 4625 Seq. ID No. 4626 IM 1 2212b Seq. ID No. 4627 Seq. ID No. 4628 IM 1 2215a Seq. ID No. 4629 Seq. ID No. 4630 Cyto 0 2215b Seq. ID No. 4631 Seq. ID No. 4632 Cyto 0 2216a Seq. ID No. 4633 Seq. ID No. 4634 Cyto 2216b Seq. ID No. 4635 Seq. ID No. 4636 Cyto 2218 Seq. ID No. 4637 Seq. ID No. 4638 Cyto 1 2220a Seq. ID No. 4645 Seq. ID No. 4646 Cyto 2220b Seq. ID No. 4647 Seq. ID No. 4648 Cyto 2220c Seq. ID No. 4649 Seq. ID No. 4650 Cyto 2221 Seq. ID No. 4651 Seq. ID No. 4652 Cyto 2222 Seq. ID No. 4653 Seq. ID No. 4654 Cyto 0 2223a Seq. ID No. 4655 Seq. ID No. 4656 Cyto 2223b Seq. ID No. 4657 Seq. ID No. 4658 Cyto 2226 Seq. ID No. 4661 Seq. ID No. 4662 Cyto 0 2227 Seq. ID No. 4663 Seq. ID No. 4664 Cyto 2228a Seq. ID No. 4665 Seq. ID No. 4666 Cyto 2228b Seq. ID No. 4667 Seq. ID No. 4668 Cyto 2228c Seq. ID No. 4669 Seq. ID No. 4670 Cyto 2231 Seq. ID No. 4671 Seq. ID No. 4672 Cyto 2232 Seq. ID No. 4673 Seq. ID No. 4674 Cyto 2234a Seq. ID No. 4675 Seq. ID No. 4676 IM 1 2234b Seq. ID No. 4677 Seq. ID No. 4678 IM 1 2234c Seq. ID No. 4679 Seq. ID No. 4680 IM 1 2236b Seq. ID No. 4683 Seq. ID No. 4684 IM 4 2238 Seq. ID No. 4685 Seq. ID No. 4686 Cyto 2240a Seq. ID No. 4689 Seq. ID No. 4690 Cyto 0 2240b Seq. ID No. 4691 Seq. ID No. 4692 Cyto 1 2240c Seq. ID No. 4693 Seq. ID No. 4694 Cyto 1 2244 Seq. ID No. 4697 Seq. ID No. 4698 Cyto 2245 Seq. ID No. 4699 Seq. ID No. 4700 OM 1 2246 Seq. ID No. 4701 Seq. ID No. 4702 IM 2248 Seq. ID No. 4703 Seq. ID No. 4704 Cyto 2253d Seq. ID No. 4713 Seq. ID No. 4714 IM 7 2256 Seq. ID No. 4719 Seq. ID No. 4720 Cyto 2257 Seq. ID No. 4721 Seq. ID No. 4722 IM 0 2259a Seq. ID No. 4723 Seq. ID No. 4724 Cyto 2259b Seq. ID No. 4725 Seq. ID No. 4726 Cyto 2260b Seq. ID No. 4727 Seq. ID No. 4728 IM 2260c Seq. ID No. 4729 Seq. ID No. 4730 IM 2262 Seq. ID No. 4731 Seq. ID No. 4732 Cyto 2263 Seq. ID No. 4733 Seq. ID No. 4734 Cyto 1 2264a Seq. ID No. 4735 Seq. ID No. 4736 Peri 1 2267 Seq. ID No. 4739 Seq. ID No. 4740 Cyto 0 2268 Seq. ID No. 4741 Seq. ID No. 4742 Cyto 0 2269 Seq. ID No. 4743 Seq. ID No. 4744 Cyto 2270 Seq. ID No. 4745 Seq. ID No. 4746 IM 1 2272 Seq. ID No. 4747 Seq. ID No. 4748 Cyto 1 2273 Seq. ID No. 4749 Seq. ID No. 4750 Cyto 2274 Seq. ID No. 4751 Seq. ID No. 4752 Cyto 2275a Seq. ID No. 4753 Seq. ID No. 4754 IM 1 2275b Seq. ID No. 4755 Seq. ID No. 4756 IM 1 2275c Seq. ID No. 4757 Seq. ID No. 4758 IM 1 2276b Seq. ID No. 4761 Seq. ID No. 4762 Cyto 1 2276c Seq. ID No. 4763 Seq. ID No. 4764 Cyto 1 2276d Seq. ID No. 4765 Seq. ID No. 4766 Cyto 1 2277a Seq. ID No. 4767 Seq. ID No. 4768 Cyto 1 2277b Seq. ID No. 4769 Seq. ID No. 4770 Cyto 1 2278a Seq. ID No. 4771 Seq. ID No. 4772 Cyto 2278b Seq. ID No. 4773 Seq. ID No. 4774 Cyto 2278c Seq. ID No. 4775 Seq. ID No. 4776 Cyto 0 2278d Seq. ID No. 4777 Seq. ID No. 4778 Cyto 0 2280 Seq. ID No. 4779 Seq. ID No. 4780 Cyto 2284 Seq. ID No. 4781 Seq. ID No. 4782 Cyto 0 2285 Seq. ID No. 4783 Seq. ID No. 4784 Cyto 2286a Seq. ID No. 4785 Seq. ID No. 4786 Cyto 2286b Seq. ID No. 4787 Seq. ID No. 4788 Cyto 2288 Seq. ID No. 4789 Seq. ID No. 4790 Peri 1 2290 Seq. ID No. 4791 Seq. ID No. 4792 Cyto 2291a Seq. ID No. 4793 Seq. ID No. 4794 Cyto 2291b Seq. ID No. 4795 Seq. ID No. 4796 Cyto 2291c Seq. ID No. 4797 Seq. ID No. 4798 Cyto 2292a Seq. ID No. 4799 Seq. ID No. 4800 Cyto 0 2292b Seq. ID No. 4801 Seq. ID No. 4802 Cyto 0 2292c Seq. ID No. 4803 Seq. ID No. 4804 Cyto 0 2294 Seq. ID No. 4805 Seq. ID No. 4806 Cyto 2297 Seq. ID No. 4807 Seq. ID No. 4808 Cyto 2298 Seq. ID No. 4809 Seq. ID No. 4810 Cyto 2299 Seq. ID No. 4811 Seq. ID No. 4812 Cyto 2301 Seq. ID No. 4815 Seq. ID No. 4816 IM 7 2302 Seq. ID No. 4817 Seq. ID No. 4818 IM 1 2303 Seq. ID No. 4819 Seq. ID No. 4820 IM 1 2304 Seq. ID No. 4821 Seq. ID No. 4822 Cyto 2306c Seq. ID No. 4823 Seq. ID No. 4824 Cyto 2307 Seq. ID No. 4825 Seq. ID No. 4826 IM 4 2309a Seq. ID No. 4829 Seq. ID No. 4830 IM 2 2309b Seq. ID No. 4831 Seq. ID No. 4832 IM 2 2309c Seq. ID No. 4833 Seq. ID No. 4834 IM 2 2310 Seq. ID No. 4835 Seq. ID No. 4836 IM 2 2311 Seq. ID No. 4837 Seq. ID No. 4838 Cyto 2312a Seq. ID No. 4839 Seq. ID No. 4840 Cyto 2312b Seq. ID No. 4841 Seq. ID No. 4842 Cyto 2312c Seq. ID No. 4843 Seq. ID No. 4844 Cyto 2314 Seq. ID No. 4845 Seq. ID No. 4846 Cyto 0 2315 Seq. ID No. 4847 Seq. ID No. 4848 Cyto 2316 Seq. ID No. 4849 Seq. ID No. 4850 Cyto 1 2317 Seq. ID No. 4851 Seq. ID No. 4852 IM 2 2321a Seq. ID No. 4855 Seq. ID No. 4856 Cyto 2321b Seq. ID No. 4857 Seq. ID No. 4858 Cyto 2321c Seq. ID No. 4859 Seq. ID No. 4860 Cyto 2322 Seq. ID No. 4861 Seq. ID No. 4862 IM 0 2327 Seq. ID No. 4865 Seq. ID No. 4866 Cyto 2328 Seq. ID No. 4867 Seq. ID No. 4868 Cyto 2330 Seq. ID No. 4877 Seq. ID No. 4878 Cyto 2331 Seq. ID No. 4879 Seq. ID No. 4880 IM 1 2333 Seq. ID No. 4881 Seq. ID No. 4882 Cyto 2335 Seq. ID No. 4883 Seq. ID No. 4884 Cyto 2336 Seq. ID No. 4885 Seq. ID No. 4886 Cyto 2337b Seq. ID No. 4887 Seq. ID No. 4888 Cyto 2338a Seq. ID No. 4889 Seq. ID No. 4890 Cyto 2338b Seq. ID No. 4891 Seq. ID No. 4892 Cyto 2338c Seq. ID No. 4893 Seq. ID No. 4894 Cyto 2342a Seq. ID No. 4895 Seq. ID No. 4896 Cyto 2342b Seq. ID No. 4897 Seq. ID No. 4898 Cyto 2342c Seq. ID No. 4899 Seq. ID No. 4900 Cyto 2344 Seq. ID No. 4901 Seq. ID No. 4902 IM 0 2345 Seq. ID No. 4903 Seq. ID No. 4904 Cyto 0 2347 Seq. ID No. 4905 Seq. ID No. 4906 Cyto 1 2348 Seq. ID No. 4907 Seq. ID No. 4908 Cyto 0 2349a Seq. ID No. 4909 Seq. ID No. 4910 Cyto 2349b Seq. ID No. 4911 Seq. ID No. 4912 Cyto 2350a Seq. ID No. 4913 Seq. ID No. 4914 Cyto 2353 Seq. ID No. 4915 Seq. ID No. 4916 Cyto 2354 Seq. ID No. 4917 Seq. ID No. 4918 Cyto 2361a Seq. ID No. 4925 Seq. ID No. 4926 Cyto 2361b Seq. ID No. 4927 Seq. ID No. 4928 Cyto 2365a Seq. ID No. 4933 Seq. ID No. 4934 Cyto 0 2365b Seq. ID No. 4935 Seq. ID No. 4936 Cyto 0 2366a Seq. ID No. 4937 Seq. ID No. 4938 Cyto 2366b Seq. ID No. 4939 Seq. ID No. 4940 Cyto 2367 Seq. ID No. 4941 Seq. ID No. 4942 Cyto 2368 Seq. ID No. 4943 Seq. ID No. 4944 Cyto 2369 Seq. ID No. 4945 Seq. ID No. 4946 Cyto 2370 Seq. ID No. 4947 Seq. ID No. 4948 IM 1 2373 Seq. ID No. 4953 Seq. ID No. 4954 Cyto 2374a Seq. ID No. 4955 Seq. ID No. 4956 Cyto 0 2374b Seq. ID No. 4957 Seq. ID No. 4958 Cyto 0 2376 Seq. ID No. 4959 Seq. ID No. 4960 IM 2377a Seq. ID No. 4961 Seq. ID No. 4962 Cyto 2377b Seq. ID No. 4963 Seq. ID No. 4964 IM 1 2378 Seq. ID No. 4965 Seq. ID No. 4966 Cyto 2379a Seq. ID No. 4967 Seq. ID No. 4968 Cyto 2379b Seq. ID No. 4969 Seq. ID No. 4970 Cyto 2380 Seq. ID No. 4971 Seq. ID No. 4972 Cyto 2381 Seq. ID No. 4973 Seq. ID No. 4974 Cyto 2384a Seq. ID No. 4977 Seq. ID No. 4978 Cyto 0 2384b Seq. ID No. 4979 Seq. ID No. 4980 Cyto 0 2386b Seq. ID No. 4981 Seq. ID No. 4982 IM 0 2386c Seq. ID No. 4983 Seq. ID No. 4984 IM 0 2387 Seq. ID No. 4985 Seq. ID No. 4986 IM 5 2391 Seq. ID No. 4989 Seq. ID No. 4990 IM 0 2392 Seq. ID No. 4991 Seq. ID No. 4992 Cyto 1 2394 Seq. ID No. 4993 Seq. ID No. 4994 IM 1 2395 Seq. ID No. 4995 Seq. ID No. 4996 IM 2396 Seq. ID No. 4997 Seq. ID No. 4998 Cyto 0 2398 Seq. ID No. 5001 Seq. ID No. 5002 Cyto 2399a Seq. ID No. 5003 Seq. ID No. 5004 Cyto 2399b Seq. ID No. 5005 Seq. ID No. 5006 Cyto 2399c Seq. ID No. 5007 Seq. ID No. 5008 Cyto 2401 Seq. ID No. 5009 Seq. ID No. 5010 Cyto 2402a Seq. ID No. 5011 Seq. ID No. 5012 IM 1 2403a Seq. ID No. 5015 Seq. ID No. 5016 Cyto 0 2403b Seq. ID No. 5017 Seq. ID No. 5018 Cyto 0 2404a Seq. ID No. 5019 Seq. ID No. 5020 Cyto 0 2404b Seq. ID No. 5021 Seq. ID No. 5022 Cyto 0 2407a Seq. ID No. 5023 Seq. ID No. 5024 IM 0 2409a Seq. ID No. 5025 Seq. ID No. 5026 Cyto 2409b Seq. ID No. 5027 Seq. ID No. 5028 Cyto 2410 Seq. ID No. 5029 Seq. ID No. 5030 Cyto 0 2413a Seq. ID No. 5033 Seq. ID No. 5034 Cyto 0 2413b Seq. ID No. 5035 Seq. ID No. 5036 Peri 0 2415a Seq. ID No. 5037 Seq. ID No. 5038 Cyto 2415b Seq. ID No. 5039 Seq. ID No. 5040 IM 2416b Seq. ID No. 5041 Seq. ID No. 5042 OM 1 2416c Seq. ID No. 5043 Seq. ID No. 5044 IM 1 2417a Seq. ID No. 5045 Seq. ID No. 5046 Cyto 1 2417b Seq. ID No. 5047 Seq. ID No. 5048 Cyto 1 2418a Seq. ID No. 5049 Seq. ID No. 5050 Cyto 2418b Seq. ID No. 5051 Seq. ID No. 5052 Cyto 2420 Seq. ID No. 5053 Seq. ID No. 5054 Cyto 0 2421 Seq. ID No. 5055 Seq. ID No. 5056 Cyto 2422b Seq. ID No. 5057 Seq. ID No. 5058 Cyto 2422c Seq. ID No. 5059 Seq. ID No. 5060 Cyto 2424a Seq. ID No. 5065 Seq. ID No. 5066 Cyto 1 2424b Seq. ID No. 5067 Seq. ID No. 5068 Cyto 1 2426 Seq. ID No. 5071 Seq. ID No. 5072 Cyto 2428a Seq. ID No. 5073 Seq. ID No. 5074 IM 3 2428b Seq. ID No. 5075 Seq. ID No. 5076 IM 3 2428c Seq. ID No. 5077 Seq. ID No. 5078 IM 3 2429 Seq. ID No. 5079 Seq. ID No. 5080 Cyto 2432 Seq. ID No. 5081 Seq. ID No. 5082 Cyto 0 2433 Seq. ID No. 5083 Seq. ID No. 5084 IM 1 2440 Seq. ID No. 5087 Seq. ID No. 5088 Cyto 0 2442a Seq. ID No. 5089 Seq. ID No. 5090 Cyto 2442b Seq. ID No. 5091 Seq. ID No. 5092 Cyto 2443 Seq. ID No. 5093 Seq. ID No. 5094 Cyto 2444a Seq. ID No. 5095 Seq. ID No. 5096 Cyto 2444b Seq. ID No. 5097 Seq. ID No. 5098 Cyto 2444c Seq. ID No. 5099 Seq. ID No. 5100 Cyto 2444d Seq. ID No. 5101 Seq. ID No. 5102 Cyto 2448b Seq. ID No. 5105 Seq. ID No. 5106 Cyto 2449a Seq. ID No. 5107 Seq. ID No. 5108 Cyto 2449b Seq. ID No. 5109 Seq. ID No. 5110 Cyto 2451 Seq. ID No. 5111 Seq. ID No. 5112 Cyto 2452 Seq. ID No. 5113 Seq. ID No. 5114 IM 0 2455 Seq. ID No. 5117 Seq. ID No. 5118 Cyto 2456a Seq. ID No. 5119 Seq. ID No. 5120 IM 4 2456b Seq. ID No. 5121 Seq. ID No. 5122 IM 5 2456e Seq. ID No. 5127 Seq. ID No. 5128 IM 9 2461a Seq. ID No. 5143 Seq. ID No. 5144 Cyto 2461b Seq. ID No. 5145 Seq. ID No. 5146 Cyto 2462a Seq. ID No. 5147 Seq. ID No. 5148 Cyto 0 2462b Seq. ID No. 5149 Seq. ID No. 5150 Cyto 0 2463a Seq. ID No. 5151 Seq. ID No. 5152 IM 1 2464 Seq. ID No. 5153 Seq. ID No. 5154 IM 1 2465a Seq. ID No. 5155 Seq. ID No. 5156 Cyto 2465b Seq. ID No. 5157 Seq. ID No. 5158 Cyto 2468b Seq. ID No. 5161 Seq. ID No. 5162 IM 1 2469a Seq. ID No. 5163 Seq. ID No. 5164 Cyto 2470 Seq. ID No. 5167 Seq. ID No. 5168 Cyto 0 2471 Seq. ID No. 5169 Seq. ID No. 5170 Cyto 2473 Seq. ID No. 5171 Seq. ID No. 5172 Cyto 2474a Seq. ID No. 5173 Seq. ID No. 5174 IM 3 2474c Seq. ID No. 5177 Seq. ID No. 5178 IM 3 2475a Seq. ID No. 5179 Seq. ID No. 5180 IM 1 2475b Seq. ID No. 5181 Seq. ID No. 5182 IM 1 2475c Seq. ID No. 5183 Seq. ID No. 5184 IM 1 2477 Seq. ID No. 5185 Seq. ID No. 5186 Cyto 2480 Seq. ID No. 5187 Seq. ID No. 5188 Cyto 2481a Seq. ID No. 5189 Seq. ID No. 5190 IM 0 2481b Seq. ID No. 5191 Seq. ID No. 5192 IM 1 2482 Seq. ID No. 5193 Seq. ID No. 5194 IM 2 2483 Seq. ID No. 5195 Seq. ID No. 5196 Cyto 2485 Seq. ID No. 5201 Seq. ID No. 5202 Cyto 1 2489 Seq. ID No. 5203 Seq. ID No. 5204 Cyto 1 2492b Seq. ID No. 5209 Seq. ID No. 5210 IM 1 2494 Seq. ID No. 5211 Seq. ID No. 5212 IM 0 2495b Seq. ID No. 5215 Seq. ID No. 5216 IM 10 2497a Seq. ID No. 5217 Seq. ID No. 5218 IM 1 2498b Seq. ID No. 5221 Seq. ID No. 5222 IM 1 2500b Seq. ID No. 5225 Seq. ID No. 5226 IM 1 2500c Seq. ID No. 5227 Seq. ID No. 5228 IM 1 2501a Seq. ID No. 5229 Seq. ID No. 5230 Cyto 2501b Seq. ID No. 5231 Seq. ID No. 5232 Cyto 2504a Seq. ID No. 5233 Seq. ID No. 5234 Cyto 2504b Seq. ID No. 5235 Seq. ID No. 5236 Cyto 2505 Seq. ID No. 5237 Seq. ID No. 5238 IM 3 2506 Seq. ID No. 5239 Seq. ID No. 5240 Cyto 2507b Seq. ID No. 5241 Seq. ID No. 5242 Cyto 2507c Seq. ID No. 5243 Seq. ID No. 5244 Cyto 2510 Seq. ID No. 5245 Seq. ID No. 5246 Cyto 2512c Seq. ID No. 5247 Seq. ID No. 5248 IM 2513a Seq. ID No. 5249 Seq. ID No. 5250 Cyto 2513b Seq. ID No. 5251 Seq. ID No. 5252 Cyto 2513c Seq. ID No. 5253 Seq. ID No. 5254 Cyto 2514 Seq. ID No. 5255 Seq. ID No. 5256 Cyto 2515 Seq. ID No. 5257 Seq. ID No. 5258 Cyto 2516a Seq. ID No. 5259 Seq. ID No. 5260 Cyto 2516b Seq. ID No. 5261 Seq. ID No. 5262 Cyto 2517a Seq. ID No. 5263 Seq. ID No. 5264 Cyto 2517b Seq. ID No. 5265 Seq. ID No. 5266 Cyto 2519a Seq. ID No. 5269 Seq. ID No. 5270 Cyto 2519b Seq. ID No. 5271 Seq. ID No. 5272 Cyto 0 2523 Seq. ID No. 5283 Seq. ID No. 5284 Cyto 0 2525b Seq. ID No. 5287 Seq. ID No. 5288 IM 1 2527a Seq. ID No. 5289 Seq. ID No. 5290 Cyto 2527b Seq. ID No. 5291 Seq. ID No. 5292 Cyto 2528a Seq. ID No. 5293 Seq. ID No. 5294 Cyto 0 2528b Seq. ID No. 5295 Seq. ID No. 5296 Cyto 0 2528c Seq. ID No. 5297 Seq. ID No. 5298 Cyto 0 2528d Seq. ID No. 5299 Seq. ID No. 5300 Cyto 0 2532b Seq. ID No. 5301 Seq. ID No. 5302 Cyto 1 2532c Seq. ID No. 5303 Seq. ID No. 5304 Cyto 1 2534 Seq. ID No. 5305 Seq. ID No. 5306 Cyto 2535a Seq. ID No. 5307 Seq. ID No. 5308 Cyto 2535b Seq. ID No. 5309 Seq. ID No. 5310 Cyto 2538 Seq. ID No. 5311 Seq. ID No. 5312 Cyto 2541 Seq. ID No. 5313 Seq. ID No. 5314 Cyto 2542a Seq. ID No. 5315 Seq. ID No. 5316 Cyto 2542b Seq. ID No. 5317 Seq. ID No. 5318 Cyto 0 2542c Seq. ID No. 5319 Seq. ID No. 5320 Cyto 0 2543 Seq. ID No. 5321 Seq. ID No. 5322 Cyto 0 2544 Seq. ID No. 5323 Seq. ID No. 5324 Cyto 0 2545 Seq. ID No. 5325 Seq. ID No. 5326 Cyto 2548a Seq. ID No. 5333 Seq. ID No. 5334 Cyto 0 2548b Seq. ID No. 5335 Seq. ID No. 5336 Cyto 0 2549 Seq. ID No. 5337 Seq. ID No. 5338 Cyto 0 2550b Seq. ID No. 5339 Seq. ID No. 5340 Cyto 2550e Seq. ID No. 5343 Seq. ID No. 5344 IM 2552 Seq. ID No. 5345 Seq. ID No. 5346 Cyto 0 2553 Seq. ID No. 5347 Seq. ID No. 5348 Cyto 2554a Seq. ID No. 5349 Seq. ID No. 5350 Cyto 2554b Seq. ID No. 5351 Seq. ID No. 5352 Cyto 2555a Seq. ID No. 5353 Seq. ID No. 5354 Cyto 2555b Seq. ID No. 5355 Seq. ID No. 5356 Cyto 0 2555c Seq. ID No. 5357 Seq. ID No. 5358 Cyto 0 2555d Seq. ID No. 5359 Seq. ID No. 5360 Cyto 0 2558a Seq. ID No. 5361 Seq. ID No. 5362 Cyto 2558b Seq. ID No. 5363 Seq. ID No. 5364 Cyto 2559 Seq. ID No. 5365 Seq. ID No. 5366 Cyto 2561 Seq. ID No. 5367 Seq. ID No. 5368 Cyto 1 2562a Seq. ID No. 5369 Seq. ID No. 5370 Cyto 2562c Seq. ID No. 5371 Seq. ID No. 5372 Cyto 2563 Seq. ID No. 5373 Seq. ID No. 5374 Cyto 2564a Seq. ID No. 5375 Seq. ID No. 5376 Cyto 2564d Seq. ID No. 5381 Seq. ID No. 5382 IM 1 2566 Seq. ID No. 5383 Seq. ID No. 5384 IM 2568 Seq. ID No. 5389 Seq. ID No. 5390 IM 2 2572 Seq. ID No. 5391 Seq. ID No. 5392 IM 0 2573 Seq. ID No. 5393 Seq. ID No. 5394 Cyto 2575 Seq. ID No. 5395 Seq. ID No. 5396 Cyto 2576 Seq. ID No. 5397 Seq. ID No. 5398 Cyto 2578 Seq. ID No. 5399 Seq. ID No. 5400 Cyto 2579b Seq. ID No. 5401 Seq. ID No. 5402 IM 2581 Seq. ID No. 5403 Seq. ID No. 5404 IM 1 2582b Seq. ID No. 5407 Seq. ID No. 5408 IM 4 2582c Seq. ID No. 5409 Seq. ID No. 5410 IM 4 2585 Seq. ID No. 5411 Seq. ID No. 5412 IM 2588 Seq. ID No. 5417 Seq. ID No. 5418 Cyto 0 2589 Seq. ID No. 5419 Seq. ID No. 5420 Cyto 1 2591 Seq. ID No. 5421 Seq. ID No. 5422 Cyto 0 2592 Seq. ID No. 5423 Seq. ID No. 5424 Cyto 2593a Seq. ID No. 5425 Seq. ID No. 5426 Cyto 0 2593b Seq. ID No. 5427 Seq. ID No. 5428 Cyto 0 2594a Seq. ID No. 5429 Seq. ID No. 5430 Cyto 2594b Seq. ID No. 5431 Seq. ID No. 5432 Cyto 2597a Seq. ID No. 5435 Seq. ID No. 5436 Cyto 2597b Seq. ID No. 5437 Seq. ID No. 5438 Cyto 2597c Seq. ID No. 5439 Seq. ID No. 5440 Cyto 2598 Seq. ID No. 5441 Seq. ID No. 5442 Cyto 0 2602 Seq. ID No. 5443 Seq. ID No. 5444 Cyto 0 2605a Seq. ID No. 5445 Seq. ID No. 5446 Cyto 2605b Seq. ID No. 5447 Seq. ID No. 5448 Cyto 2606 Seq. ID No. 5449 Seq. ID No. 5450 Cyto 2608 Seq. ID No. 5451 Seq. ID No. 5452 Cyto 2611 Seq. ID No. 5455 Seq. ID No. 5456 Cyto 2613 Seq. ID No. 5457 Seq. ID No. 5458 Cyto 0 2616e Seq. ID No. 5467 Seq. ID No. 5468 IM 5 2616f Seq. ID No. 5469 Seq. ID No. 5470 IM 6 2616g Seq. ID No. 5471 Seq. ID No. 5472 IM 7 2616h Seq. ID No. 5473 Seq. ID No. 5474 IM 7 2617a Seq. ID No. 5475 Seq. ID No. 5476 IM 2617b Seq. ID No. 5477 Seq. ID No. 5478 IM 2618a Seq. ID No. 5479 Seq. ID No. 5480 IM 2618b Seq. ID No. 5481 Seq. ID No. 5482 IM 2619 Seq. ID No. 5483 Seq. ID No. 5484 Cyto 2620 Seq. ID No. 5485 Seq. ID No. 5486 IM 0 2621a Seq. ID No. 5487 Seq. ID No. 5488 IM 1 2623a Seq. ID No. 5489 Seq. ID No. 5490 Cyto 2624a Seq. ID No. 5493 Seq. ID No. 5494 Cyto 0 2624b Seq. ID No. 5495 Seq. ID No. 5496 Cyto 0 2625b Seq. ID No. 5499 Seq. ID No. 5500 IM 3 2626a Seq. ID No. 5501 Seq. ID No. 5502 Cyto 2626b Seq. ID No. 5503 Seq. ID No. 5504 Cyto 2627a Seq. ID No. 5505 Seq. ID No. 5506 Cyto 2627b Seq. ID No. 5507 Seq. ID No. 5508 Cyto 2629a Seq. ID No. 5511 Seq. ID No. 5512 Cyto 2633a Seq. ID No. 5519 Seq. ID No. 5520 Cyto 2633b Seq. ID No. 5521 Seq. ID No. 5522 Cyto 2633c Seq. ID No. 5523 Seq. ID No. 5524 Cyto 2633e Seq. ID No. 5527 Seq. ID No. 5528 IM 1 2643a Seq. ID No. 5535 Seq. ID No. 5536 Cyto 1 2643b Seq. ID No. 5537 Seq. ID No. 5538 IM 2 2645 Seq. ID No. 5539 Seq. ID No. 5540 Cyto 2647 Seq. ID No. 5541 Seq. ID No. 5542 Cyto 2649 Seq. ID No. 5547 Seq. ID No. 5548 IM 1 2650 Seq. ID No. 5549 Seq. ID No. 5550 IM 3 2652a Seq. ID No. 5551 Seq. ID No. 5552 Cyto 2652b Seq. ID No. 5553 Seq. ID No. 5554 Cyto 2655a Seq. ID No. 5555 Seq. ID No. 5556 Cyto 2655b Seq. ID No. 5557 Seq. ID No. 5558 IM 1 2656 Seq. ID No. 5559 Seq. ID No. 5560 Cyto 0 2658a Seq. ID No. 5561 Seq. ID No. 5562 Cyto 0 2658b Seq. ID No. 5563 Seq. ID No. 5564 Cyto 0 2659a Seq. ID No. 5565 Seq. ID No. 5566 IM 3 2659b Seq. ID No. 5567 Seq. ID No. 5568 IM 4 2662 Seq. ID No. 5571 Seq. ID No. 5572 Cyto 2664a Seq. ID No. 5573 Seq. ID No. 5574 Cyto 2664b Seq. ID No. 5575 Seq. ID No. 5576 Cyto 2665 Seq. ID No. 5577 Seq. ID No. 5578 IM 1 2666a Seq. ID No. 5579 Seq. ID No. 5580 Cyto 0 2666b Seq. ID No. 5581 Seq. ID No. 5582 Cyto 0 2667a Seq. ID No. 5583 Seq. ID No. 5584 IM 2667b Seq. ID No. 5585 Seq. ID No. 5586 IM 2674b Seq. ID No. 5599 Seq. ID No. 5600 IM 11 2676 Seq. ID No. 5601 Seq. ID No. 5602 Cyto 0 2677a Seq. ID No. 5603 Seq. ID No. 5604 IM 1 2677b Seq. ID No. 5605 Seq. ID No. 5606 IM 1 2677c Seq. ID No. 5607 Seq. ID No. 5608 IM 1 2679c Seq. ID No. 5613 Seq. ID No. 5614 IM 5 2679d Seq. ID No. 5615 Seq. ID No. 5616 IM 5 2680a Seq. ID No. 5617 Seq. ID No. 5618 Cyto 2680b Seq. ID No. 5619 Seq. ID No. 5620 Cyto 2684a Seq. ID No. 5627 Seq. ID No. 5628 IM 0 2684b Seq. ID No. 5629 Seq. ID No. 5630 IM 0 2686 Seq. ID No. 5631 Seq. ID No. 5632 Cyto 0 2688b Seq. ID No. 5635 Seq. ID No. 5636 IM 4 2690b Seq. ID No. 5645 Seq. ID No. 5646 IM 1 2690c Seq. ID No. 5647 Seq. ID No. 5648 IM 1 2693 Seq. ID No. 5651 Seq. ID No. 5652 Cyto 2694a Seq. ID No. 5653 Seq. ID No. 5654 Cyto 0 2694b Seq. ID No. 5655 Seq. ID No. 5656 Cyto 0 2695 Seq. ID No. 5657 Seq. ID No. 5658 Cyto 0 2696b Seq. ID No. 5661 Seq. ID No. 5662 IM 8 2705 Seq. ID No. 5663 Seq. ID No. 5664 Cyto 2709 Seq. ID No. 5665 Seq. ID No. 5666 Cyto 2712 Seq. ID No. 5669 Seq. ID No. 5670 IM 1 2713 Seq. ID No. 5671 Seq. ID No. 5672 Cyto 2714 Seq. ID No. 5673 Seq. ID No. 5674 Cyto 2716a Seq. ID No. 5675 Seq. ID No. 5676 Cyto 2716b Seq. ID No. 5677 Seq. ID No. 5678 Cyto 2716c Seq. ID No. 5679 Seq. ID No. 5680 Cyto 2721a Seq. ID No. 5691 Seq. ID No. 5692 Cyto 2721b Seq. ID No. 5693 Seq. ID No. 5694 IM 1 2722a Seq. ID No. 5695 Seq. ID No. 5696 Cyto 1 2722b Seq. ID No. 5697 Seq. ID No. 5698 Cyto 1 2724 Seq. ID No. 5701 Seq. ID No. 5702 Cyto 2726 Seq. ID No. 5707 Seq. ID No. 5708 Cyto 2731a Seq. ID No. 5713 Seq. ID No. 5714 Cyto 2731b Seq. ID No. 5715 Seq. ID No. 5716 Cyto 2732 Seq. ID No. 5717 Seq. ID No. 5718 Cyto 2734b Seq. ID No. 5721 Seq. ID No. 5722 IM 4 2734c Seq. ID No. 5723 Seq. ID No. 5724 IM 5 2735a Seq. ID No. 5725 Seq. ID No. 5726 Cyto 2 2735b Seq. ID No. 5727 Seq. ID No. 5728 Cyto 2 2738b Seq. ID No. 5731 Seq. ID No. 5732 IM 11 2742a Seq. ID No. 5737 Seq. ID No. 5738 Cyto 2743a Seq. ID No. 5741 Seq. ID No. 5742 Cyto 1 2743b Seq. ID No. 5743 Seq. ID No. 5744 Cyto 1 2744 Seq. ID No. 5745 Seq. ID No. 5746 IM 2745a Seq. ID No. 5747 Seq. ID No. 5748 Cyto 1 2745b Seq. ID No. 5749 Seq. ID No. 5750 Cyto 1 2746 Seq. ID No. 5751 Seq. ID No. 5752 Cyto 2747a Seq. ID No. 5753 Seq. ID No. 5754 Cyto 0 2747b Seq. ID No. 5755 Seq. ID No. 5756 Cyto 0 2748a Seq. ID No. 5757 Seq. ID No. 5758 IM 10 2748b Seq. ID No. 5759 Seq. ID No. 5760 IM 10 2748c Seq. ID No. 5761 Seq. ID No. 5762 IM 10 2749d Seq. ID No. 5769 Seq. ID No. 5770 IM 9 2750a Seq. ID No. 5773 Seq. ID No. 5774 Cyto 2750b Seq. ID No. 5775 Seq. ID No. 5776 Cyto 2752 Seq. ID No. 5777 Seq. ID No. 5778 Cyto 0 2753 Seq. ID No. 5779 Seq. ID No. 5780 Cyto 2757a Seq. ID No. 5781 Seq. ID No. 5782 IM 4 2758b Seq. ID No. 5787 Seq. ID No. 5788 Cyto 0 2758c Seq. ID No. 5789 Seq. ID No. 5790 Cyto 0 2759a Seq. ID No. 5793 Seq. ID No. 5794 Cyto 0 2759b Seq. ID No. 5795 Seq. ID No. 5796 Cyto 0 2760b Seq. ID No. 5799 Seq. ID No. 5800 IM 1 2760c Seq. ID No. 5801 Seq. ID No. 5802 IM 1 2762 Seq. ID No. 5803 Seq. ID No. 5804 Cyto 0 2763a Seq. ID No. 5805 Seq. ID No. 5806 IM 2 2763b Seq. ID No. 5807 Seq. ID No. 5808 IM 2 2763c Seq. ID No. 5809 Seq. ID No. 5810 IM 2 2764 Seq. ID No. 5811 Seq. ID No. 5812 IM 2765b Seq. ID No. 5813 Seq. ID No. 5814 Cyto 1 2765c Seq. ID No. 5815 Seq. ID No. 5816 Cyto 1 2766a Seq. ID No. 5817 Seq. ID No. 5818 IM 0 2766b Seq. ID No. 5819 Seq. ID No. 5820 IM 0 2768a Seq. ID No. 5821 Seq. ID No. 5822 IM 0 2768b Seq. ID No. 5823 Seq. ID No. 5824 IM 0 2768c Seq. ID No. 5825 Seq. ID No. 5826 IM 0 2769a Seq. ID No. 5827 Seq. ID No. 5828 IM 0 2771a Seq. ID No. 5831 Seq. ID No. 5832 Cyto 2771b Seq. ID No. 5833 Seq. ID No. 5834 Cyto 2773 Seq. ID No. 5835 Seq. ID No. 5836 IM 1 2774a Seq. ID No. 5837 Seq. ID No. 5838 IM 2 2774b Seq. ID No. 5839 Seq. ID No. 5840 IM 2 2774c Seq. ID No. 5841 Seq. ID No. 5842 IM 2 2776a Seq. ID No. 5843 Seq. ID No. 5844 Cyto 1 2776b Seq. ID No. 5845 Seq. ID No. 5846 Cyto 1 2777 Seq. ID No. 5847 Seq. ID No. 5848 Cyto 2778 Seq. ID No. 5849 Seq. ID No. 5850 Cyto 2779 Seq. ID No. 5851 Seq. ID No. 5852 IM 1 2780 Seq. ID No. 5853 Seq. ID No. 5854 Cyto 2784 Seq. ID No. 5855 Seq. ID No. 5856 Cyto 2785a Seq. ID No. 5857 Seq. ID No. 5858 Cyto 1 2785b Seq. ID No. 5859 Seq. ID No. 5860 Cyto 1 2786a Seq. ID No. 5861 Seq. ID No. 5862 IM 1 2786b Seq. ID No. 5863 Seq. ID No. 5864 IM 1 2786c Seq. ID No. 5865 Seq. ID No. 5866 IM 1 2787a Seq. ID No. 5867 Seq. ID No. 5868 Cyto 1 2787b Seq. ID No. 5869 Seq. ID No. 5870 Cyto 1 2787c Seq. ID No. 5871 Seq. ID No. 5872 Cyto 1 2788b Seq. ID No. 5873 Seq. ID No. 5874 Cyto 1 2789 Seq. ID No. 5875 Seq. ID No. 5876 Cyto 0 2790 Seq. ID No. 5877 Seq. ID No. 5878 Cyto 2793 Seq. ID No. 5881 Seq. ID No. 5882 Cyto 2798 Seq. ID No. 5887 Seq. ID No. 5888 IM 2 2799b Seq. ID No. 5891 Seq. ID No. 5892 IM 1 2804 Seq. ID No. 5897 Seq. ID No. 5898 IM 0 2809 Seq. ID No. 5903 Seq. ID No. 5904 Cyto 2810b Seq. ID No. 5907 Seq. ID No. 5908 IM 3 2810d Seq. ID No. 5911 Seq. ID No. 5912 IM 4 2812 Seq. ID No. 5913 Seq. ID No. 5914 Cyto 2814 Seq. ID No. 5915 Seq. ID No. 5916 IM 1 2815 Seq. ID No. 5917 Seq. ID No. 5918 Cyto 2816 Seq. ID No. 5919 Seq. ID No. 5920 Cyto 2818c Seq. ID No. 5925 Seq. ID No. 5926 IM 5 2819 Seq. ID No. 5931 Seq. ID No. 5932 Cyto 2820 Seq. ID No. 5933 Seq. ID No. 5934 Cyto 2821a Seq. ID No. 5935 Seq. ID No. 5936 Cyto 2821b Seq. ID No. 5937 Seq. ID No. 5938 Cyto 2822b Seq. ID No. 5941 Seq. ID No. 5942 IM 11 2823 Seq. ID No. 5943 Seq. ID No. 5944 Cyto 0 2824a Seq. ID No. 5945 Seq. ID No. 5946 Cyto 1 2824b Seq. ID No. 5947 Seq. ID No. 5948 Cyto 1 2829a Seq. ID No. 5949 Seq. ID No. 5950 Cyto 2829b Seq. ID No. 5951 Seq. ID No. 5952 Cyto 2831b Seq. ID No. 5953 Seq. ID No. 5954 Cyto 2832 Seq. ID No. 5955 Seq. ID No. 5956 Cyto 2833 Seq. ID No. 5957 Seq. ID No. 5958 Cyto 2834a Seq. ID No. 5959 Seq. ID No. 5960 Cyto 0 2834b Seq. ID No. 5961 Seq. ID No. 5962 Cyto 0 2837a Seq. ID No. 5963 Seq. ID No. 5964 IM 2 2837b Seq. ID No. 5965 Seq. ID No. 5966 IM 3 2842a Seq. ID No. 5967 Seq. ID No. 5968 Cyto 2842b Seq. ID No. 5969 Seq. ID No. 5970 Cyto 2843a Seq. ID No. 5971 Seq. ID No. 5972 Cyto 2843b Seq. ID No. 5973 Seq. ID No. 5974 Cyto 2845 Seq. ID No. 5975 Seq. ID No. 5976 Cyto 2846a Seq. ID No. 5977 Seq. ID No. 5978 Cyto 2846b Seq. ID No. 5979 Seq. ID No. 5980 Peri 2848 Seq. ID No. 5981 Seq. ID No. 5982 Cyto 2850 Seq. ID No. 5983 Seq. ID No. 5984 Cyto 2851 Seq. ID No. 5985 Seq. ID No. 5986 Cyto 0 2852 Seq. ID No. 5987 Seq. ID No. 5988 IM 1 2853 Seq. ID No. 5989 Seq. ID No. 5990 Cyto 2854a Seq. ID No. 5991 Seq. ID No. 5992 IM 2854b Seq. ID No. 5993 Seq. ID No. 5994 IM 2855 Seq. ID No. 5995 Seq. ID No. 5996 Cyto 2856a Seq. ID No. 5997 Seq. ID No. 5998 IM 8 2856b Seq. ID No. 5999 Seq. ID No. 6000 IM 8 2856c Seq. ID No. 6001 Seq. ID No. 6002 IM 8 2857 Seq. ID No. 6003 Seq. ID No. 6004 Cyto 2859 Seq. ID No. 6005 Seq. ID No. 6006 Cyto 2860a Seq. ID No. 6007 Seq. ID No. 6008 Cyto 0 2860b Seq. ID No. 6009 Seq. ID No. 6010 Cyto 0 2860c Seq. ID No. 6011 Seq. ID No. 6012 Cyto 0 2862 Seq. ID No. 6013 Seq. ID No. 6014 Cyto 2 2863 Seq. ID No. 6015 Seq. ID No. 6016 Cyto 2864 Seq. ID No. 6017 Seq. ID No. 6018 Cyto 2 2868a Seq. ID No. 6019 Seq. ID No. 6020 Cyto 2868b Seq. ID No. 6021 Seq. ID No. 6022 IM 2871 Seq. ID No. 6029 Seq. ID No. 6030 Cyto 2872 Seq. ID No. 6031 Seq. ID No. 6032 Cyto 2875 Seq. ID No. 6033 Seq. ID No. 6034 Cyto 0 2877 Seq. ID No. 6035 Seq. ID No. 6036 Cyto 2879a Seq. ID No. 6037 Seq. ID No. 6038 Cyto 0 2879b Seq. ID No. 6039 Seq. ID No. 6040 Cyto 0 2879c Seq. ID No. 6041 Seq. ID No. 6042 Cyto 0 2882 Seq. ID No. 6045 Seq. ID No. 6046 IM 2 2883b Seq. ID No. 6049 Seq. ID No. 6050 IM 7 2883c Seq. ID No. 6051 Seq. ID No. 6052 IM 7 2886a Seq. ID No. 6055 Seq. ID No. 6056 Cyto 0 2886b Seq. ID No. 6057 Seq. ID No. 6058 Cyto 0 2887b Seq. ID No. 6061 Seq. ID No. 6062 IM 2 2890 Seq. ID No. 6065 Seq. ID No. 6066 IM 1 2891b Seq. ID No. 6069 Seq. ID No. 6070 Cyto 1 2891c Seq. ID No. 6071 Seq. ID No. 6072 Cyto 1 2893b Seq. ID No. 6073 Seq. ID No. 6074 IM 1 2894a Seq. ID No. 6075 Seq. ID No. 6076 Cyto 2894b Seq. ID No. 6077 Seq. ID No. 6078 Cyto 2894c Seq. ID No. 6079 Seq. ID No. 6080 Cyto 2895 Seq. ID No. 6081 Seq. ID No. 6082 IM 2897a Seq. ID No. 6083 Seq. ID No. 6084 Cyto 2897b Seq. ID No. 6085 Seq. ID No. 6086 Cyto 2901b Seq. ID No. 6093 Seq. ID No. 6094 IM 2 2904 Seq. ID No. 6097 Seq. ID No. 6098 Cyto 2905a Seq. ID No. 6099 Seq. ID No. 6100 Cyto 2905b Seq. ID No. 6101 Seq. ID No. 6102 Cyto 0 2909a Seq. ID No. 6105 Seq. ID No. 6106 Cyto 2912 Seq. ID No. 6113 Seq. ID No. 6114 Cyto 2915a Seq. ID No. 6119 Seq. ID No. 6120 Cyto 2915b Seq. ID No. 6121 Seq. ID No. 6122 Cyto 2915c Seq. ID No. 6123 Seq. ID No. 6124 Cyto 2916 Seq. ID No. 6125 Seq. ID No. 6126 Cyto 2917 Seq. ID No. 6127 Seq. ID No. 6128 OM 1 2918 Seq. ID No. 6129 Seq. ID No. 6130 Cyto 0 2920 Seq. ID No. 6131 Seq. ID No. 6132 IM 2 2921 Seq. ID No. 6133 Seq. ID No. 6134 IM 0 2923b Seq. ID No. 6139 Seq. ID No. 6140 Cyto 2923c Seq. ID No. 6141 Seq. ID No. 6142 Cyto 2925a Seq. ID No. 6143 Seq. ID No. 6144 Cyto 2925b Seq. ID No. 6145 Seq. ID No. 6146 Cyto 2926a Seq. ID No. 6147 Seq. ID No. 6148 Cyto 2926b Seq. ID No. 6149 Seq. ID No. 6150 Cyto 2926c Seq. ID No. 6151 Seq. ID No. 6152 Cyto 2928a Seq. ID No. 6153 Seq. ID No. 6154 Cyto 2928b Seq. ID No. 6155 Seq. ID No. 6156 Cyto 2928c Seq. ID No. 6157 Seq. ID No. 6158 Cyto 2933a Seq. ID No. 6167 Seq. ID No. 6168 Cyto 2934 Seq. ID No. 6171 Seq. ID No. 6172 Cyto 1 2935a Seq. ID No. 6173 Seq. ID No. 6174 Cyto 2935b Seq. ID No. 6175 Seq. ID No. 6176 Cyto 0 2936 Seq. ID No. 6177 Seq. ID No. 6178 IM 2 2939a Seq. ID No. 6179 Seq. ID No. 6180 Cyto 2939b Seq. ID No. 6181 Seq. ID No. 6182 Cyto 2943c Seq. ID No. 6193 Seq. ID No. 6194 IM 6 2943d Seq. ID No. 6195 Seq. ID No. 6196 IM 6 2945b Seq. ID No. 6199 Seq. ID No. 6200 IM 0 2947 Seq. ID No. 6201 Seq. ID No. 6202 Cyto 2948c Seq. ID No. 6207 Seq. ID No. 6208 IM 6 2950a Seq. ID No. 6211 Seq. ID No. 6212 Cyto 2950b Seq. ID No. 6213 Seq. ID No. 6214 Cyto 2951 Seq. ID No. 6215 Seq. ID No. 6216 Cyto 2954 Seq. ID No. 6219 Seq. ID No. 6220 IM 7 2955f Seq. ID No. 6231 Seq. ID No. 6232 IM 12 2955g Seq. ID No. 6233 Seq. ID No. 6234 IM 12 2958b Seq. ID No. 6239 Seq. ID No. 6240 IM 2 2962a Seq. ID No. 6247 Seq. ID No. 6248 Cyto 2963 Seq. ID No. 6251 Seq. ID No. 6252 Cyto 2965b Seq. ID No. 6255 Seq. ID No. 6256 IM 2 2965c Seq. ID No. 6257 Seq. ID No. 6258 IM 2 2967 Seq. ID No. 6261 Seq. ID No. 6262 Cyto 2971a Seq. ID No. 6269 Seq. ID No. 6270 Cyto 0 2971b Seq. ID No. 6271 Seq. ID No. 6272 Cyto 0 2975 Seq. ID No. 6277 Seq. ID No. 6278 Cyto 1 2977a Seq. ID No. 6279 Seq. ID No. 6280 IM 4 2977b Seq. ID No. 6281 Seq. ID No. 6282 IM 4 2979 Seq. ID No. 6287 Seq. ID No. 6288 IM 4 2980b Seq. ID No. 6291 Seq. ID No. 6292 IM 5 2980c Seq. ID No. 6293 Seq. ID No. 6294 IM 5 2980d Seq. ID No. 6295 Seq. ID No. 6296 IM 5 2980e Seq. ID No. 6297 Seq. ID No. 6298 IM 5 2984 Seq. ID No. 6299 Seq. ID No. 6300 Cyto 0 2986c Seq. ID No. 6305 Seq. ID No. 6306 IM 7 2988a Seq. ID No. 6307 Seq. ID No. 6308 Cyto 1 2988b Seq. ID No. 6309 Seq. ID No. 6310 Cyto 1 2988c Seq. ID No. 6311 Seq. ID No. 6312 Cyto 1 2989 Seq. ID No. 6313 Seq. ID No. 6314 Cyto 2990 Seq. ID No. 6315 Seq. ID No. 6316 Cyto 0 2991a Seq. ID No. 6317 Seq. ID No. 6318 IM 2991b Seq. ID No. 6319 Seq. ID No. 6320 Cyto 0 2991c Seq. ID No. 6321 Seq. ID No. 6322 Cyto 0 2992 Seq. ID No. 6323 Seq. ID No. 6324 IM 4 2995a Seq. ID No. 6329 Seq. ID No. 6330 Cyto 1 2995b Seq. ID No. 6331 Seq. ID No. 6332 Cyto 1 2997 Seq. ID No. 6333 Seq. ID No. 6334 Cyto 2998a Seq. ID No. 6335 Seq. ID No. 6336 Cyto 2998b Seq. ID No. 6337 Seq. ID No. 6338 Cyto 2999 Seq. ID No. 6339 Seq. ID No. 6340 Cyto 3001 Seq. ID No. 6341 Seq. ID No. 6342 Cyto 3003 Seq. ID No. 6343 Seq. ID No. 6344 Cyto 3005 Seq. ID No. 6345 Seq. ID No. 6346 Cyto 3008a Seq. ID No. 6347 Seq. ID No. 6348 Cyto 3008b Seq. ID No. 6349 Seq. ID No. 6350 Cyto 3008c Seq. ID No. 6351 Seq. ID No. 6352 Cyto 3008d Seq. ID No. 6353 Seq. ID No. 6354 Cyto 3010a Seq. ID No. 6355 Seq. ID No. 6356 Cyto 3010b Seq. ID No. 6357 Seq. ID No. 6358 Cyto 3012 Seq. ID No. 6359 Seq. ID No. 6360 Cyto 3015 Seq. ID No. 6361 Seq. ID No. 6362 IM 7 3016c Seq. ID No. 6367 Seq. ID No. 6368 IM 7 3017 Seq. ID No. 6369 Seq. ID No. 6370 Cyto 3018a Seq. ID No. 6371 Seq. ID No. 6372 Cyto 3018b Seq. ID No. 6373 Seq. ID No. 6374 Cyto 3020 Seq. ID No. 6375 Seq. ID No. 6376 IM 3022 Seq. ID No. 6379 Seq. ID No. 6380 Cyto 3024b Seq. ID No. 6385 Seq. ID No. 6386 Cyto 1 3026a Seq. ID No. 6387 Seq. ID No. 6388 Cyto 3026b Seq. ID No. 6389 Seq. ID No. 6390 Cyto 3028a Seq. ID No. 6391 Seq. ID No. 6392 Cyto 3028b Seq. ID No. 6393 Seq. ID No. 6394 Cyto 3028c Seq. ID No. 6395 Seq. ID No. 6396 Cyto 3029a Seq. ID No. 6397 Seq. ID No. 6398 Cyto 3029b Seq. ID No. 6399 Seq. ID No. 6400 Cyto 3031a Seq. ID No. 6401 Seq. ID No. 6402 Cyto 3031b Seq. ID No. 6403 Seq. ID No. 6404 Cyto 3032a Seq. ID No. 6405 Seq. ID No. 6406 Cyto 3032b Seq. ID No. 6407 Seq. ID No. 6408 Cyto 3033a Seq. ID No. 6409 Seq. ID No. 6410 Cyto 3033b Seq. ID No. 6411 Seq. ID No. 6412 Cyto 3035 Seq. ID No. 6413 Seq. ID No. 6414 Cyto 1 3037b Seq. ID No. 6417 Seq. ID No. 6418 IM 1 3038 Seq. ID No. 6419 Seq. ID No. 6420 Cyto 3040a Seq. ID No. 6421 Seq. ID No. 6422 Cyto 3040b Seq. ID No. 6423 Seq. ID No. 6424 Cyto 3044 Seq. ID No. 6433 Seq. ID No. 6434 IM 1 3045a Seq. ID No. 6435 Seq. ID No. 6436 Cyto 3045b Seq. ID No. 6437 Seq. ID No. 6438 Cyto 3048a Seq. ID No. 6439 Seq. ID No. 6440 Cyto 3049a Seq. ID No. 6441 Seq. ID No. 6442 Cyto 3049b Seq. ID No. 6443 Seq. ID No. 6444 Cyto 3049c Seq. ID No. 6445 Seq. ID No. 6446 Cyto 3051a Seq. ID No. 6447 Seq. ID No. 6448 Cyto 3051b Seq. ID No. 6449 Seq. ID No. 6450 Cyto 3052 Seq. ID No. 6451 Seq. ID No. 6452 Cyto 3054 Seq. ID No. 6453 Seq. ID No. 6454 Cyto 3055a Seq. ID No. 6455 Seq. ID No. 6456 Cyto 3055b Seq. ID No. 6457 Seq. ID No. 6458 Cyto 3057 Seq. ID No. 6459 Seq. ID No. 6460 Cyto 3059 Seq. ID No. 6461 Seq. ID No. 6462 Cyto 3060 Seq. ID No. 6463 Seq. ID No. 6464 IM 5 3061 Seq. ID No. 6465 Seq. ID No. 6466 Peri 1 3062 Seq. ID No. 6467 Seq. ID No. 6468 IM 5 3063a Seq. ID No. 6469 Seq. ID No. 6470 Cyto 0 3063b Seq. ID No. 6471 Seq. ID No. 6472 Cyto 0 3065a Seq. ID No. 6475 Seq. ID No. 6476 Cyto 3065b Seq. ID No. 6477 Seq. ID No. 6478 Cyto 3067 Seq. ID No. 6481 Seq. ID No. 6482 Cyto 3068 Seq. ID No. 6483 Seq. ID No. 6484 Cyto 3069 Seq. ID No. 6485 Seq. ID No. 6486 Cyto 3071 Seq. ID No. 6487 Seq. ID No. 6488 Cyto 3072a Seq. ID No. 6489 Seq. ID No. 6490 Cyto 3073 Seq. ID No. 6491 Seq. ID No. 6492 Cyto 3074 Seq. ID No. 6493 Seq. ID No. 6494 Cyto 3075 Seq. ID No. 6495 Seq. ID No. 6496 Cyto 3077a Seq. ID No. 6499 Seq. ID No. 6500 Cyto 3077b Seq. ID No. 6501 Seq. ID No. 6502 Cyto 3077c Seq. ID No. 6503 Seq. ID No. 6504 Cyto 3078 Seq. ID No. 6505 Seq. ID No. 6506 Cyto 1 3079 Seq. ID No. 6507 Seq. ID No. 6508 IM 1 3081a Seq. ID No. 6509 Seq. ID No. 6510 Cyto 3081b Seq. ID No. 6511 Seq. ID No. 6512 Cyto 3083c Seq. ID No. 6513 Seq. ID No. 6514 Cyto 3083d Seq. ID No. 6515 Seq. ID No. 6516 Cyto 3086 Seq. ID No. 6519 Seq. ID No. 6520 Cyto 3087a Seq. ID No. 6521 Seq. ID No. 6522 Cyto 3087c Seq. ID No. 6523 Seq. ID No. 6524 Cyto 3088 Seq. ID No. 6525 Seq. ID No. 6526 Cyto 3089a Seq. ID No. 6527 Seq. ID No. 6528 Cyto 3089b Seq. ID No. 6529 Seq. ID No. 6530 Cyto 3090 Seq. ID No. 6531 Seq. ID No. 6532 Cyto 3091 Seq. ID No. 6533 Seq. ID No. 6534 Cyto 3092a Seq. ID No. 6535 Seq. ID No. 6536 Cyto 3092b Seq. ID No. 6537 Seq. ID No. 6538 Cyto 3095 Seq. ID No. 6539 Seq. ID No. 6540 IM 1 3097 Seq. ID No. 6545 Seq. ID No. 6546 Cyto 3098a Seq. ID No. 6547 Seq. ID No. 6548 Cyto 0 3098b Seq. ID No. 6549 Seq. ID No. 6550 Cyto 0 3098c Seq. ID No. 6551 Seq. ID No. 6552 Cyto 0 3099 Seq. ID No. 6553 Seq. ID No. 6554 Cyto 3101 Seq. ID No. 6559 Seq. ID No. 6560 Cyto 3102 Seq. ID No. 6561 Seq. ID No. 6562 Peri 2 3103b Seq. ID No. 6563 Seq. ID No. 6564 Cyto 3104 Seq. ID No. 6565 Seq. ID No. 6566 Cyto 3105 Seq. ID No. 6567 Seq. ID No. 6568 Cyto 3106 Seq. ID No. 6569 Seq. ID No. 6570 Cyto 3108a Seq. ID No. 6575 Seq. ID No. 6576 Cyto 3108b Seq. ID No. 6577 Seq. ID No. 6578 Peri 3109 Seq. ID No. 6579 Seq. ID No. 6580 Cyto 3110b Seq. ID No. 6583 Seq. ID No. 6584 IM 2 3113 Seq. ID No. 6585 Seq. ID No. 6586 IM 1 3116 Seq. ID No. 6587 Seq. ID No. 6588 Cyto 1 3118a Seq. ID No. 6589 Seq. ID No. 6590 Cyto 3118b Seq. ID No. 6591 Seq. ID No. 6592 Cyto 3121 Seq. ID No. 6605 Seq. ID No. 6606 Cyto 3122a Seq. ID No. 6607 Seq. ID No. 6608 Cyto 2 3122b Seq. ID No. 6609 Seq. ID No. 6610 Cyto 2 3123a Seq. ID No. 6611 Seq. ID No. 6612 IM 0 3123b Seq. ID No. 6613 Seq. ID No. 6614 IM 0 3124 Seq. ID No. 6615 Seq. ID No. 6616 IM 1 3126 Seq. ID No. 6617 Seq. ID No. 6618 Cyto 0 3129a Seq. ID No. 6619 Seq. ID No. 6620 Cyto 2 3129b Seq. ID No. 6621 Seq. ID No. 6622 Cyto 2 3131 Seq. ID No. 6623 Seq. ID No. 6624 IM 2 3134a Seq. ID No. 6625 Seq. ID No. 6626 Cyto 0 3134b Seq. ID No. 6627 Seq. ID No. 6628 IM 0 3138 Seq. ID No. 6629 Seq. ID No. 6630 IM 0 3141 Seq. ID No. 6633 Seq. ID No. 6634 Cyto 2 3145a Seq. ID No. 6635 Seq. ID No. 6636 Cyto 0 3147a Seq. ID No. 6641 Seq. ID No. 6642 Cyto 3149a Seq. ID No. 6647 Seq. ID No. 6648 Cyto

Listed in Table 7 are 287 ORFs whose Pfam results predict possible secreted, surface or membrane localization of proteins encoded by the ORFs. TABLE 7 PFAM ORF DNA SEQ ID Protein SEQ ID Number Number Number Pfam  51c Seq. ID No. 89 Seq. ID No. 90 Sodium: dicarboxylate symporter family  80c Seq. ID No. 145 Seq. ID No. 146 Formate/nitrite transporter  85b Seq. ID No. 155 Seq. ID No. 156 ABC transporter  88 Seq. ID No. 167 Seq. ID No. 168 Binding-protein-dependent transport s  91b Seq. ID No. 173 Seq. ID No. 174 NLPA lipoprotein  99 Seq. ID No. 191 Seq. ID No. 192 Phosphotransferase system, EIIC  109d Seq. ID No. 215 Seq. ID No. 216 ABC 3 transport family  111b Seq. ID No. 219 Seq. ID No. 220 ABC 3 transport family  112a Seq. ID No. 221 Seq. ID No. 222 ABC transporter  112b Seq. ID No. 223 Seq. ID No. 224 ABC transporter  114 Seq. ID No. 225 Seq. ID No. 226 Periplasmic solute binding protein fa  121 Seq. ID No. 233 Seq. ID No. 234 ABC transporter  124c Seq. ID No. 239 Seq. ID No. 240 Binding-protein-dependent transport s  129b Seq. ID No. 251 Seq. ID No. 252 Phosphotransferase system, EIIC  129c Seq. ID No. 253 Seq. ID No. 254 PTS system, Fructose specific IIB sub  138a Seq. ID No. 271 Seq. ID No. 272 E1-E2 ATPase  145d Seq. ID No. 291 Seq. ID No. 292 AbgT putative transporter family  162c Seq. ID No. 331 Seq. ID No. 332 Cobalt transport protein  165a Seq. ID No. 341 Seq. ID No. 342 ABC transporter  167 Seq. ID No. 345 Seq. ID No. 346 ABC transporter  180b Seq. ID No. 375 Seq. ID No. 376 eubacterial secY protein  245c Seq. ID No. 501 Seq. ID No. 502 Permease family  246b Seq. ID No. 505 Seq. ID No. 506 Cell cycle protein  248b Seq. ID No. 511 Seq. ID No. 512 Cell cycle protein  255c Seq. ID No. 529 Seq. ID No. 530 Sodium: solute symporter family  273a Seq. ID No. 567 Seq. ID No. 568 phosphotransferase system, EIIB  273b Seq. ID No. 569 Seq. ID No. 570 Phosphotransferase system, EIIC  277c Seq. ID No. 575 Seq. ID No. 576 ApbE family  283b Seq. ID No. 593 Seq. ID No. 594 Bacterial extracellular solute-bindin  284a Seq. ID No. 595 Seq. ID No. 596 Binding-protein-dependent transport s  286a Seq. ID No. 601 Seq. ID No. 602 ABC transporter  311 Seq. ID No. 637 Seq. ID No. 638 ABC transporter  315 Seq. ID No. 649 Seq. ID No. 650 ABC transporter  318c Seq. ID No. 661 Seq. ID No. 662 NLPA lipoprotein  321 Seq. ID No. 669 Seq. ID No. 670 NLPA lipoprotein  324 Seq. ID No. 675 Seq. ID No. 676 NLPA lipoprotein  327c Seq. ID No. 681 Seq. ID No. 682 Binding-protein-dependent transport s  329 Seq. ID No. 683 Seq. ID No. 684 ABC transporter  342h Seq. ID No. 729 Seq. ID No. 730 Uncharacterized membrane protein fami  351 Seq. ID No. 753 Seq. ID No. 754 ABC transporter  358b Seq. ID No. 779 Seq. ID No. 780 Na+/H+ antiporter family  384b Seq. ID No. 827 Seq. ID No. 828 Phosphotransferase system, EIIC  391 Seq. ID No. 839 Seq. ID No. 840 Glycosyl transferase family 8  418b Seq. ID No. 895 Seq. ID No. 896 E1-E2 ATPase  435 Seq. ID No. 939 Seq. ID No. 940 Metallo-beta-lactamase superfamily  450a Seq. ID No. 969 Seq. ID No. 970 ABC transporter  452e Seq. ID No. 985 Seq. ID No. 986 Predicted permease  464c Seq. ID No. 1015 Seq. ID No. 1016 Cation transport protein  472f Seq. ID No. 1039 Seq. ID No. 1040 Cation transport protein  492 Seq. ID No. 1075 Seq. ID No. 1076 NLPA lipoprotein  524b Seq. ID No. 1137 Seq. ID No. 1138 60 Kd inner membrane protein  533 Seq. ID No. 1155 Seq. ID No. 1156 Phosphotransferase system, EIIC  539c Seq. ID No. 1163 Seq. ID No. 1164 ABC transporter  543a Seq. ID No. 1175 Seq. ID No. 1176 ABC transporter  561 Seq. ID No. 1223 Seq. ID No. 1224 ABC transporter  564c Seq. ID No. 1231 Seq. ID No. 1232 BioY family  570b Seq. ID No. 1237 Seq. ID No. 1238 ABC transporter  573 Seq. ID No. 1241 Seq. ID No. 1242 ABC transporter  586a Seq. ID No. 1261 Seq. ID No. 1262 Large-conductance mechanosensitive ch  613d Seq. ID No. 1331 Seq. ID No. 1332 Sodium/hydrogen exchanger family  618 Seq. ID No. 1339 Seq. ID No. 1340 Mechanosensitive ion channel  631d Seq. ID No. 1369 Seq. ID No. 1370 5′-nucleotidase, C-terminal domain  698 Seq. ID No. 1477 Seq. ID No. 1478 LrgA family  722c Seq. ID No. 1517 Seq. ID No. 1518 PTS system Galactitol-specific IIC co  728b Seq. ID No. 1531 Seq. ID No. 1532 PTS system sorbose-specific iic compo  730d Seq. ID No. 1539 Seq. ID No. 1540 PTS system mannose/fructose/sorbose f  738c Seq. ID No. 1549 Seq. ID No. 1550 PTS system Galactitol-specific IIC co  744 Seq. ID No. 1563 Seq. ID No. 1564 Bacterial extracellular solute-bindin  745b Seq. ID No. 1567 Seq. ID No. 1568 Binding-protein-dependent transport s  746b Seq. ID No. 1571 Seq. ID No. 1572 Binding-protein-dependent transport s  747 Seq. ID No. 1573 Seq. ID No. 1574 ABC transporter  754d Seq. ID No. 1589 Seq. ID No. 1590 PTS system, Lactose/Cellobiose specif  758 Seq. ID No. 1595 Seq. ID No. 1596 PTS system, Lactose/Cellobiose specif  788b Seq. ID No. 1647 Seq. ID No. 1648 Binding-protein-dependent transport s  792 Seq. ID No. 1657 Seq. ID No. 1658 ABC transporter  859d Seq. ID No. 1771 Seq. ID No. 1772 E1-E2 ATPase  866b Seq. ID No. 1785 Seq. ID No. 1786 ABC transporter  868b Seq. ID No. 1789 Seq. ID No. 1790 Binding-protein-dependent transport s  885 Seq. ID No. 1819 Seq. ID No. 1820 Histidine kinase-, DNA gyrase B-, and  886 Seq. ID No. 1821 Seq. ID No. 1822 D-alanyl-D-alanine carboxypeptidase  977a Seq. ID No. 1969 Seq. ID No. 1970 NLPA lipoprotein  998b Seq. ID No. 2015 Seq. ID No. 2016 PAP2 superfamily 1016c Seq. ID No. 2047 Seq. ID No. 2048 ABC transporter 1036a Seq. ID No. 2087 Seq. ID No. 2088 Binding-protein-dependent transport s 1036b Seq. ID No. 2089 Seq. ID No. 2090 Bacterial extracellular solute-bindin 1037 Seq. ID No. 2093 Seq. ID No. 2094 ABC transporter 1047b Seq. ID No. 2115 Seq. ID No. 2116 Periplasmic solute binding protein fa 1049a Seq. ID No. 2117 Seq. ID No. 2118 ABC transporter 1050d Seq. ID No. 2127 Seq. ID No. 2128 ABC 3 transport family 1060b Seq. ID No. 2141 Seq. ID No. 2142 Bacterial transferase hexapeptide (fo 1077e Seq. ID No. 2179 Seq. ID No. 2180 Polysaccharide biosynthesis protein 1094b Seq. ID No. 2207 Seq. ID No. 2208 Peptidase family M41 1100 Seq. ID No. 2223 Seq. ID No. 2224 ABC transporter 1127 Seq. ID No. 2253 Seq. ID No. 2254 ABC transporter 1140c Seq. ID No. 2275 Seq. ID No. 2276 E1-E2 ATPase 1149 Seq. ID No. 2301 Seq. ID No. 2302 ABC transporter 1152g Seq. ID No. 2315 Seq. ID No. 2316 Binding-protein-dependent transport s 1155g Seq. ID No. 2329 Seq. ID No. 2330 Binding-protein-dependent transport s 1165 Seq. ID No. 2343 Seq. ID No. 2344 NLP/P60 family 1167b Seq. ID No. 2349 Seq. ID No. 2350 His Kinase A (phosphoacceptor) domain 1171c Seq. ID No. 2363 Seq. ID No. 2364 ABC transporter 1179c Seq. ID No. 2381 Seq. ID No. 2382 Metallo-beta-lactamase superfamily 1180e Seq. ID No. 2391 Seq. ID No. 2392 Phospholipase D. Active site motif 1191 Seq. ID No. 2417 Seq. ID No. 2418 ABC transporter 1192b Seq. ID No. 2421 Seq. ID No. 2422 Peptidase family M48 1194 Seq. ID No. 2423 Seq. ID No. 2424 LemA family 1197 Seq. ID No. 2429 Seq. ID No. 2430 Peptidase family U7 1221a Seq. ID No. 2481 Seq. ID No. 2482 ABC transporter 1224a Seq. ID No. 2487 Seq. ID No. 2488 CAAX amino terminal protease family 1224b Seq. ID No. 2489 Seq. ID No. 2490 CAAX amino terminal protease family 1224c Seq. ID No. 2491 Seq. ID No. 2492 CAAX amino terminal protease family 1233a Seq. ID No. 2509 Seq. ID No. 2510 ABC transporter 1234c Seq. ID No. 2519 Seq. ID No. 2520 Uncharacterised protein family (UPF00 1237 Seq. ID No. 2525 Seq. ID No. 2526 LysM domain 1245d Seq. ID No. 2547 Seq. ID No. 2548 AbgT putative transporter family 1246b Seq. ID No. 2553 Seq. ID No. 2554 Metallo-beta-lactamase superfamily 1250e Seq. ID No. 2563 Seq. ID No. 2564 Sodium:dicarboxylate symporter family 1258c Seq. ID No. 2587 Seq. ID No. 2588 E1-E2 ATPase 1266b Seq. ID No. 2599 Seq. ID No. 2600 AzIC protein 1268b Seq. ID No. 2607 Seq. ID No. 2608 ABC transporter 1271 Seq. ID No. 2613 Seq. ID No. 2614 ABC transporter 1288 Seq. ID No. 2651 Seq. ID No. 2652 Cell envelope-related transcriptional 1305b Seq. ID No. 2675 Seq. ID No. 2676 ABC transporter 1308b Seq. ID No. 2681 Seq. ID No. 2682 Predicted permease 1308e Seq. ID No. 2687 Seq. ID No. 2688 Predicted permease 1315 Seq. ID No. 2693 Seq. ID No. 2694 Histidine kinase-, DNA gyrase B-, and 1318 Seq. ID No. 2699 Seq. ID No. 2700 Phosphate-binding protein 1319b Seq. ID No. 2703 Seq. ID No. 2704 Binding-protein-dependent transport s 1320c Seq. ID No. 2709 Seq. ID No. 2710 Binding-protein-dependent transport s 1321 Seq. ID No. 2711 Seq. ID No. 2712 ABC transporter 1333 Seq. ID No. 2727 Seq. ID No. 2728 ABC transporter 1348 Seq. ID No. 2753 Seq. ID No. 2754 Prolipoprotein diacylglyceryl transfe 1384a Seq. ID No. 2819 Seq. ID No. 2820 Preprotein translocase SecG subunit 1384b Seq. ID No. 2821 Seq. ID No. 2822 Preprotein translocase SecG subunit 1384c Seq. ID No. 2823 Seq. ID No. 2824 Preprotein translocase SecG subunit 1408 Seq. ID No. 2867 Seq. ID No. 2868 ABC transporter 1410 Seq. ID No. 2871 Seq. ID No. 2872 ABC transporter 1426b Seq. ID No. 2907 Seq. ID No. 2908 Ribonuclease BN-like family 1431 Seq. ID No. 2919 Seq. ID No. 2920 ABC transporter 1442b Seq. ID No. 2957 Seq. ID No. 2958 ABC transporter 1447b Seq. ID No. 2971 Seq. ID No. 2972 Sodium/glutamate symporter 1451 Seq. ID No. 2979 Seq. ID No. 2980 ABC transporter 1457c Seq. ID No. 2999 Seq. ID No. 3000 Na+/Pi-cotransporter 1462b Seq. ID No. 3005 Seq. ID No. 3006 ABC transporter 1466d Seq. ID No. 3019 Seq. ID No. 3020 ABC transporter 1471 Seq. ID No. 3035 Seq. ID No. 3036 Ion transport protein 1484b Seq. ID No. 3065 Seq. ID No. 3066 Divalent cation transporter 1488g Seq. ID No. 3085 Seq. ID No. 3086 Divalent cation transporter 1517c Seq. ID No. 3149 Seq. ID No. 3150 Mechanosensitive ion channel 1530b Seq. ID No. 3165 Seq. ID No. 3166 Transglycosylase 1543 Seq. ID No. 3183 Seq. ID No. 3184 NLP/P60 family 1554c Seq. ID No. 3203 Seq. ID No. 3204 Bacterial type II secretion system pr 1556c Seq. ID No. 3211 Seq. ID No. 3212 ABC transporter 1573 Seq. ID No. 3251 Seq. ID No. 3252 ABC transporter 1578 Seq. ID No. 3259 Seq. ID No. 3260 ABC transporter 1606b Seq. ID No. 3319 Seq. ID No. 3320 Histidine kinase-, DNA gyrase B-, and 1607b Seq. ID No. 3323 Seq. ID No. 3324 60 Kd inner membrane protein 1616b Seq. ID No. 3335 Seq. ID No. 3336 FtsK/SpoIIIE family 1619 Seq. ID No. 3337 Seq. ID No. 3338 Basic membrane protein 1623c Seq. ID No. 3347 Seq. ID No. 3348 ABC transporter 1626b Seq. ID No. 3359 Seq. ID No. 3360 Branched-chain amino acid transport s 1634c Seq. ID No. 3377 Seq. ID No. 3378 Mannosyl-glycoprotein endo-beta-N-ace 1639b Seq. ID No. 3379 Seq. ID No. 3380 LysM domain 1646f Seq. ID No. 3399 Seq. ID No. 3400 Polysaccharide biosynthesis protein 1659c Seq. ID No. 3425 Seq. ID No. 3426 Na+/H+ antiporter family 1683b Seq. ID No. 3483 Seq. ID No. 3484 Ribonuclease BN-like family 1688c Seq. ID No. 3495 Seq. ID No. 3496 Glycosyl transferase 1689a Seq. ID No. 3497 Seq. ID No. 3498 Glycosyl transferase 1694d Seq. ID No. 3519 Seq. ID No. 3520 Cell envelope-related transcriptional 1699b Seq. ID No. 3529 Seq. ID No. 3530 Polysaccharide biosynthesis protein 1737b Seq. ID No. 3599 Seq. ID No. 3600 GA module 1743 Seq. ID No. 3611 Seq. ID No. 3612 GA module 1744b Seq. ID No. 3615 Seq. ID No. 3616 GA module 1747 Seq. ID No. 3619 Seq. ID No. 3620 GA module 1769b Seq. ID No. 3663 Seq. ID No. 3664 Type IV leader peptidase family 1804b Seq. ID No. 3739 Seq. ID No. 3740 Na+/H+ antiporter subunit 1808d Seq. ID No. 3759 Seq. ID No. 3760 NADH-Ubiquinone/plastoquinone (comple 1809f Seq. ID No. 3771 Seq. ID No. 3772 NADH-Ubiquinone/plastoquinone (comple 1816c Seq. ID No. 3797 Seq. ID No. 3798 Transglycosylase 1833 Seq. ID No. 3825 Seq. ID No. 3826 5′-nucleotidase, C-terminal domain 1838c Seq. ID No. 3841 Seq. ID No. 3842 ABC transporter 1842d Seq. ID No. 3855 Seq. ID No. 3856 Phosphotransferase system, EIIC 1845c Seq. ID No. 3863 Seq. ID No. 3864 Voltage gated chloride channel 1861b Seq. ID No. 3901 Seq. ID No. 3902 ABC transporter 1875c Seq. ID No. 3929 Seq. ID No. 3930 Signal peptidase I 1925 Seq. ID No. 4015 Seq. ID No. 4016 Anion-transporting ATPase 1926 Seq. ID No. 4017 Seq. ID No. 4018 ABC transporter 1939c Seq. ID No. 4055 Seq. ID No. 4056 ABC transporter 1946c Seq. ID No. 4075 Seq. ID No. 4076 Sodium: alanine symporter family 1951c Seq. ID No. 4085 Seq. ID No. 4086 ABC transporter 1953 Seq. ID No. 4089 Seq. ID No. 4090 Patatin-like phospholipase 1957 Seq. ID No. 4099 Seq. ID No. 4100 ABC transporter 1958c Seq. ID No. 4105 Seq. ID No. 4106 Branched-chain amino acid transport s 1969 Seq. ID No. 4129 Seq. ID No. 4130 Signal peptidase (SPase) II 2008 Seq. ID No. 4203 Seq. ID No. 4204 Prokaryotic diacylglycerol kinase 2023b Seq. ID No. 4243 Seq. ID No. 4244 Rhomboid family 2024d Seq. ID No. 4251 Seq. ID No. 4252 Penicillin binding protein transpepti 2074b Seq. ID No. 4343 Seq. ID No. 4344 N-acetylmuramoyl-L-alanine amidase 2094 Seq. ID No. 4383 Seq. ID No. 4384 ABC transporter 2142b Seq. ID No. 4475 Seq. ID No. 4476 Phosphatidate cytidylyltransferase 2146 Seq. ID No. 4481 Seq. ID No. 4482 NLPA lipoprotein 2147c Seq. ID No. 4487 Seq. ID No. 4488 Binding-protein-dependent transport s 2149b Seq. ID No. 4491 Seq. ID No. 4492 ABC transporter 2165 Seq. ID No. 4533 Seq. ID No. 4534 Uncharacterised protein family (UPF01 2212b Seq. ID No. 4627 Seq. ID No. 4628 LysM domain 2249 Seq. ID No. 4705 Seq. ID No. 4706 Bacterial extracellular solute-bindin 2253d Seq. ID No. 4713 Seq. ID No. 4714 Binding-protein-dependent transport s 2255b Seq. ID No. 4717 Seq. ID No. 4718 Binding-protein-dependent transport s 2256 Seq. ID No. 4719 Seq. ID No. 4720 ABC transporter 2260c Seq. ID No. 4729 Seq. ID No. 4730 ABC transporter 2288 Seq. ID No. 4789 Seq. ID No. 4790 Patatin-like phospholipase 2290 Seq. ID No. 4791 Seq. ID No. 4792 ATP synthase subunit D 2291a Seq. ID No. 4793 Seq. ID No. 4794 ATP synthase alpha/beta family, nucle 2292c Seq. ID No. 4803 Seq. ID No. 4804 ATP synthase alpha/beta family, nucle 2300 Seq. ID No. 4813 Seq. ID No. 4814 ATP synthase subunit C 2301 Seq. ID No. 4815 Seq. ID No. 4816 V-type ATPase 116 kDa subunit family 2307 Seq. ID No. 4825 Seq. ID No. 4826 Binding-protein-dependent transport s 2309c Seq. ID No. 4833 Seq. ID No. 4834 Binding-protein-dependent transport s 2311 Seq. ID No. 4837 Seq. ID No. 4838 ABC transporter 2329d Seq. ID No. 4875 Seq. ID No. 4876 Competence protein 2331 Seq. ID No. 4879 Seq. ID No. 4880 Helix-hairpin-helix motif 2357 Seq. ID No. 4919 Seq. ID No. 4920 Histidine kinase-, DNA gyrase B-, and 2363b Seq. ID No. 4931 Seq. ID No. 4932 Uncharacterized BCR, YceG family COG1 2370 Seq. ID No. 4947 Seq. ID No. 4948 Bacterial transferase hexapeptide (fo 2387 Seq. ID No. 4985 Seq. ID No. 4986 Uncharacterized BCR, YitT family COG1 2428c Seq. ID No. 5077 Seq. ID No. 5078 Pyridoxal-phosphate dependent enzyme 2453 Seq. ID No. 5115 Seq. ID No. 5116 Periplasmic binding protein 2455 Seq. ID No. 5117 Seq. ID No. 5118 ABC transporter 2456e Seq. ID No. 5127 Seq. ID No. 5128 FecCD transport family 2458g Seq. ID No. 5141 Seq. ID No. 5142 FecCD transport family 2482 Seq. ID No. 5193 Seq. ID No. 5194 YGGT family 2495b Seq. ID No. 5215 Seq. ID No. 5216 Glycosyl transferase 2497b Seq. ID No. 5219 Seq. ID No. 5220 Penicillin binding protein transpepti 2520b Seq. ID No. 5275 Seq. ID No. 5276 PEP-utilizing enzyme, TIM barrel doma 2564d Seq. ID No. 5381 Seq. ID No. 5382 D-alanyl-D-alanine carboxypeptidase 2568 Seq. ID No. 5389 Seq. ID No. 5390 ABC transporter 2582c Seq. ID No. 5409 Seq. ID No. 5410 Cobalt transport protein 2585 Seq. ID No. 5411 Seq. ID No. 5412 ABC transporter 2617a Seq. ID No. 5475 Seq. ID No. 5476 ABC transporter 2623b Seq. ID No. 5491 Seq. ID No. 5492 PPIC-type PPIASE domain 2629b Seq. ID No. 5513 Seq. ID No. 5514 Bacterial extracellular solute-bindin 2633a Seq. ID No. 5519 Seq. ID No. 5520 Bacterial extracellular solute-bindin 2633d Seq. ID No. 5525 Seq. ID No. 5526 Bacterial extracellular solute-bindin 2637a Seq. ID No. 5529 Seq. ID No. 5530 Bacterial extracellular solute-bindin 2643b Seq. ID No. 5537 Seq. ID No. 5538 Transglycosylase 2655b Seq. ID No. 5557 Seq. ID No. 5558 Uncharacterized secreted proteins, Ya 2666b Seq. ID No. 5581 Seq. ID No. 5582 MutS family, N-terminal putative DNA 2674b Seq. ID No. 5599 Seq. ID No. 5600 Carbon starvation protein CstA 2688c Seq. ID No. 5637 Seq. ID No. 5638 CDP-alcohol phosphatidyltransferase 2718c Seq. ID No. 5685 Seq. ID No. 5686 Uncharacterized BCR, COG1963 2734c Seq. ID No. 5723 Seq. ID No. 5724 Cation efflux family 2747b Seq. ID No. 5755 Seq. ID No. 5756 Metallo-beta-lactamase superfamily 2748c Seq. ID No. 5761 Seq. ID No. 5762 Uncharacterized membrane protein fami 2801b Seq. ID No. 5895 Seq. ID No. 5896 HAMP domain 2805b Seq. ID No. 5901 Seq. ID No. 5902 Predicted permease 2809 Seq. ID No. 5903 Seq. ID No. 5904 ABC transporter 2810d Seq. ID No. 5911 Seq. ID No. 5912 Predicted permease 2812 Seq. ID No. 5913 Seq. ID No. 5914 ABC transporter 2816 Seq. ID No. 5919 Seq. ID No. 5920 ABC transporter 2818b Seq. ID No. 5923 Seq. ID No. 5924 Binding-protein-dependent transport s 2818e Seq. ID No. 5929 Seq. ID No. 5930 Bacterial extracellular solute-bindin 2856c Seq. ID No. 6001 Seq. ID No. 6002 E1-E2 ATPase 2881 Seq. ID No. 6043 Seq. ID No. 6044 Mannosyl-glycoprotein endo-beta-N-ace 2883d Seq. ID No. 6053 Seq. ID No. 6054 Predicted permease 2886a Seq. ID No. 6055 Seq. ID No. 6056 ABC transporter 2900b Seq. ID No. 6089 Seq. ID No. 6090 LysM domain 2902 Seq. ID No. 6095 Seq. ID No. 6096 LysM domain 2909d Seq. ID No. 6111 Seq. ID No. 6112 Sulfatase 2913b Seq. ID No. 6117 Seq. ID No. 6118 Histidine kinase-, DNA gyrase B-, and 2931c Seq. ID No. 6165 Seq. ID No. 6166 Sodium: solute symporter family 2933b Seq. ID No. 6169 Seq. ID No. 6170 BNR/Asp-box repeat 2941c Seq. ID No. 6187 Seq. ID No. 6188 ABC transporter 2943d Seq. ID No. 6195 Seq. ID No. 6196 ABC transporter 2954 Seq. ID No. 6219 Seq. ID No. 6220 Bacitracin resistance protein BacA 2955g Seq. ID No. 6233 Seq. ID No. 6234 Permease family 2971a Seq. ID No. 6269 Seq. ID No. 6270 ABC transporter 2974b Seq. ID No. 6275 Seq. ID No. 6276 Predicted permease 2977a Seq. ID No. 6279 Seq. ID No. 6280 Chromate transporter 2979 Seq. ID No. 6287 Seq. ID No. 6288 Chromate transporter 2980e Seq. ID No. 6297 Seq. ID No. 6298 NQR2, RnfD, RnfE family 2984 Seq. ID No. 6299 Seq. ID No. 6300 Respiratory-chain NADH dehydrogenase 2986c Seq. ID No. 6305 Seq. ID No. 6306 NQR2, RnfD, RnfE family 2988c Seq. ID No. 6311 Seq. ID No. 6312 Respiratory-chain NADH dehydrogenase 3017 Seq. ID No. 6369 Seq. ID No. 6370 ABC transporter 3022 Seq. ID No. 6379 Seq. ID No. 6380 Clp amino terminal domain 3116 Seq. ID No. 6587 Seq. ID No. 6588 Peptidase C1-like family 3118b Seq. ID No. 6591 Seq. ID No. 6592 Peptidase C1-like family

Listed in Table 8 are ORFs whose BlastP results predict for possible secreted, surface or membrane localization. Keywords used in the search are: MHC, murein, mycolic, NisP, penicillin, peptidoglycan, periplasmic, phosphatidate, pilus, protease, receptor, response regulator, sacculus, secreted protein, sensor protein, signal, surface, teichoic, toxin, transferring, transmembrane, virulence, vitronectin, wall, spor, sporulatio, immunoglobulin, IgG, IgE, IgM, IgD, cueat, teichoic, serum, transport, transporter, channel, porin, hemolysin, phosphatase, vaccine, polysaccharide, rhamnose, dexB, aliA, cap, cps, wze, wzh. A total of 319 ORFs whose BlastP results predict for a possible secreted, surface or membrane localization for the polypeptides encoded by the ORFs are listed in Table 8. TABLE 8 _BLASTP DNA Protein ORF SEQ ID SEQ ID Blast ‘e’ Number Number Number Keyword Description Value   4b Seq. ID No. Seq. ID No. transport transporter, Bacillus 4.00E−15 9 10 halodurans Bacteria; Firmicu . . .  10 Seq. ID No. Seq. ID No. virulence Neisseria 5.00E−35 17 18 meningitidis virulence pro . . . Aau72997 . . .  38a Seq. ID No. Seq. ID No. porin Cephalosporin C 6.00E−30 45 46 amidase enzyme. 3/1991 Aar10055 . . .  39a Seq. ID No. Seq. ID No. capsular PgsC, Bacillus 1.00E−18 49 50 subtilis Bacteria; Firmicutes; Baci . . .  40 Seq. ID No. Seq. ID No. capB CapB, Bacillus 9.00E−95 53 54 subtilis Bacteria; Firmicutes; Baci . . .  41c Seq. ID No. Seq. ID No. capA PgsA, Bacillus 2.00E−44 59 60 subtilis Bacteria; Firmicutes; Baci . . .  51c Seq. ID No. Seq. ID No. membrane putative 2.00E−44 89 90 transmembrane symporter, Campylobacter je . . .  80c Seq. ID No. Seq. ID No. transport Listeria 6.00E−32 145 146 monocytogenes Bacteria; Firmicutes; Bacil . . .  85c Seq. ID No. Seq. ID No. envelop H. pylori cell 2.00E−50 157 158 envelope transporter . . . Aaw20861 . . .  88 Seq. ID No. Seq. ID No. TRANSMEMBRANE PROBABLE 2.00E−24 167 168 TRANSMEMBRANE ABC TRANSPORTER PROTEIN, Ra . . .  91a Seq. ID No. Seq. ID No. membrane outer membrane 5.00E−25 171 172 protein, Xylella fastidiosa 9a5c Ba . . .  99 Seq. ID No. Seq. ID No. membrane putative PTS 8.00E−38 191 192 transmembrane compon . . . AL096852 . . .  109d Seq. ID No. Seq. ID No. membrane High-affinity zinc 2.00E−60 215 216 uptake system membran, Fusobact . . .  111a Seq. ID No. Seq. ID No. transporter YtgC, Bacillus 7.00E−34 217 218 subtilis Bacteria; Firmicutes; Baci . . .  114 Seq. ID No. Seq. ID No. adhesin surface adhesin A 6.00E−42 225 226 precursor, Bacillus halodurans B . . .  124c Seq. ID No. Seq. ID No. membrane ABC transporter 1.00E−105 239 240 membrane-spanning permease, Strep . . .  129c Seq. ID No. Seq. ID No. immunogenic Propionibacterium 5.00E−77 253 254 acnes immunogenic . . . Aau44300 . . .  138b Seq. ID No. Seq. ID No. transport cadmium- 1.00E−114 273 274 transporting ATPase, Bacillus halodurans B . . .  143 Seq. ID No. Seq. ID No. immunogenic Propionibacterium 1.00E−14 277 278 acnes immunogenic . . . Aau4245 . . .  145c Seq. ID No. Seq. ID No. membrane hypothetical integral 1.00E−92 289 290 membrane protein, Neisseria . . .  162b Seq. ID No. Seq. ID No. membrane putative ABC 2.00E−58 329 330 transporter membrane-spannin, Strepto . . .  165b Seq. ID No. Seq. ID No. transport ABC transporter 7.00E−90 343 344 ATP-binding protein, Lactococcus l . . .  167 Seq. ID No. Seq. ID No. transport putative ABC 5.00E−99 345 346 transporter, Enterococcus faecium Bac . . .  180b Seq. ID No. Seq. ID No. membrane preprotein 1.00E−101 375 376 translocase, SecY subunit, Streptococcu . . .  245c Seq. ID No. Seq. ID No. transporter uracil permease, 2.00E−80 501 502 Bacillus caldolyticus Bacteria; F . . .  246b Seq. ID No. Seq. ID No. sporulation stage V sporulation 3.00E−46 505 506 protein E, Bacillus halodurans . . .  248b Seq. ID No. Seq. ID No. sporulation stage V sporulation 3.00E−46 511 512 protein E, Bacillus halodurans . . .  249b Seq. ID No. Seq. ID No. peptidoglycan putative 4.00E−47 515 516 peptidoglycan GlcNAc deacetylase, Strepto . . .  255c Seq. ID No. Seq. ID No. transporter putative 1.00E−52 529 530 sodium/glucose cotransporter, Salmonella . . .  273b Seq. ID No. Seq. ID No. immunogenic Propionibacterium 5.00E−56 569 570 acnes immunogenic . . . Aau41330 . . .  277c Seq. ID No. Seq. ID No. lipoprotein Listeria 4.00E−91 575 576 monocytogenes Bacteria; Firmicutes; Bacil . . .  283b Seq. ID No. Seq. ID No. transport probable amino acid 3.00E−19 593 594 ABC transporter, Clostridium p . . .  284a Seq. ID No. Seq. ID No. membrane membrane protein, 5.00E−39 595 596 Vibrio harveyi Bacteria; Proteob . . .  311 Seq. ID No. Seq. ID No. transporter ABC transporter 5.00E−58 637 638 (ATP-binding protein), Bacillus ha . . .  318b Seq. ID No. Seq. ID No. lipoprotein PUTATIVE OUTER 4.00E−34 659 660 MEMBRANE LIPOPROTEIN, Sinorhizobium . . .  321 Seq. ID No. Seq. ID No. lipoprotein Staphylococcus 1.00E−54 669 670 aureus subsp. aureus MW2 Bacteria; . . .  324 Seq. ID No. Seq. ID No. lipoprotein Staphylococcus 1.00E−55 675 676 aureus subsp. aureus MW2 Bacteria; . . .  327c Seq. ID No. Seq. ID No. transport ABC transporter, 9.00E−36 681 682 permease protein, putative, Strep . . .  342h Seq. ID No. Seq. ID No. transmembrane putative 1.00E−33 729 730 transmembrane efflux protein, Methanosarc . . .  358b Seq. ID No. Seq. ID No. transport transport protein, 1.00E−119 779 780 Fusobacterium nucleatum subsp. . . .  382b Seq. ID No. Seq. ID No. secreted protein putative secreted 2.00E−37 819 820 protein, Listeria innocua Bacter . . .  418b Seq. ID No. Seq. ID No. transport metal transporting 1.00E−138 895 896 ATPase, Lactococcus lactis subs . . .  427a Seq. ID No. Seq. ID No. capsular unknown, 1.00E−46 921 922 Staphylococcus aureus Bacteria; Firmicute . . .  431 Seq. ID No. Seq. ID No. protease Listeria innocua 2.00E−41 935 936 Bacteria; Firmicutes; Bacillus/Cl . . .  441b Seq. ID No. Seq. ID No. response regulator histidine kinase 1.00E−135 955 956 YycG, Staphylococcus aureus Bacte . . .  448 Seq. ID No. Seq. ID No. transporter accessory protein, 1.00E−17 967 968 Enterococcus faecalis subsp. li . . .  452e Seq. ID No. Seq. ID No. transporter membrane subunit, 8.00E−55 985 986 Enterococcus faecalis subsp. liq . . .  464d Seq. ID No. Seq. ID No. membrane Trk transporter 4.00E−82 1017 1018 membrane-spanning protein - K, Str . . .  472f Seq. ID No. Seq. ID No. membrane potassium uptake 1.00E−73 1039 1040 protein, Trk family, Streptococcu . . .  492 Seq. ID No. Seq. ID No. lipoprotein putative outer 4.00E−28 1075 1076 membrane lipoprotein, Salmonella ty . . .  499a Seq. ID No. Seq. ID No. phosphatase Exopolyphosphatase- 1.00E−110 1089 1090 related proteins, Thermoanaerob . . .  524b Seq. ID No. Seq. ID No. sporulation stage III sporulation, 4.00E−38 1137 1138 Bacillus subtilis Bacteria; . . .  561 Seq. ID No. Seq. ID No. membrane ABC transporter 2.00E−63 1223 1224 ATP- binding/membrane spannin, Stre . . .  573 Seq. ID No. Seq. ID No. transport ABC-type 2.00E−61 1241 1242 multidrug/protein/lipid transpor, Thermoa . . .  609a Seq. ID No. Seq. ID No. spore spore wall protein 2 6.00E−23 1315 1316 precursor, Encephalitozoon in . . .  613d Seq. ID No. Seq. ID No. TRANSMEMBRANE HYPOTHETICAL 5.00E−13 1331 1332 TRANSMEMBRANE PROTEIN, Ralstonia sola . . .  631d Seq. ID No. Seq. ID No. Signal PROBABLE 5′- 4.00E−60 1369 1370 NUCLEOTIDASE PRECURSOR (SIGNAL, Sinorhi . . .  687 Seq. ID No. Seq. ID No. transmembrane Chlamydia 6.00E−45 1459 1460 pneumoniae transmembrane p . . . Aay34923 . . .  722c Seq. ID No. Seq. ID No. immunogenic Propionibacterium 3.00E−16 1517 1518 acnes immunogenic . . . Aau6647 . . .  743b Seq. ID No. Seq. ID No. transport putative alpha- 2.00E−27 1561 1562 glucosidase, Alicyclobacillus acido . . .  744 Seq. ID No. Seq. ID No. transport Glicerol-3-phosphate 1.00E−93 1563 1564 ABC-transporter, Clostridium . . .  745b Seq. ID No. Seq. ID No. transport Glycerol-3- 2.00E−49 1567 1568 phosphate ABC- transporter, permeas, Clo . . .  746b Seq. ID No. Seq. ID No. transport glycerol-3-phosphate 1.00E−51 1571 1572 ABC transporter (permease), B . . .  747 Seq. ID No. Seq. ID No. transport Multiple sugar- 2.00E−95 1573 1574 binding ABC- transporter, MSM, Clost . . .  762b Seq. ID No. Seq. ID No. cpsL transposase, 5.00E−44 1601 1602 Streptococcus pneumoniae Bacteria; Fi . . .  763b Seq. ID No. Seq. ID No. capsular transposase, 4.00E−16 1607 1608 Staphylococcus aureus Bacteria; Firmi . . .  767 Seq. ID No. Seq. ID No. capsular transposase, 4.00E−14 1613 1614 Staphylococcus aureus Bacteria; Firmi . . .  770c Seq. ID No. Seq. ID No. transport acetylornitine 2.00E−32 1619 1620 deacetylase, Bacillus subtilis Bact . . .  785 Seq. ID No. Seq. ID No. phosphatase phosphatase, 9.00E−29 1641 1642 Lactococcus lactis subsp. lactis Bact . . .  788b Seq. ID No. Seq. ID No. transport Staphylococcus 1.00E−19 1647 1648 aureus subsp. aureus MW2 Bacteria; . . .  789c Seq. ID No. Seq. ID No. transport Staphylococcus 3.00E−31 1653 1654 aureus subsp. aureus MW2 Bacteria; . . .  792 Seq. ID No. Seq. ID No. transport Staphylococcus 2.00E−87 1657 1658 aureus subsp. aureus N315 Bacteria; . . .  794d Seq. ID No. Seq. ID No. transporter alkylphosphonate 4.00E−26 1665 1666 ABC tranporte, Bacillus haloduran . . .  813 Seq. ID No. Seq. ID No. transporter cadmium resistance 3.00E−57 1699 1700 transporter, putative, Streptoc . . .  830 Seq. ID No. Seq. ID No. cpsA Thermostable 1.00E−50 1713 1714 carboxypeptidase (cpsA-2), Sulfolobus . . .  851b Seq. ID No. Seq. ID No. penicillin B. lactofermentum 3.00E−23 1751 1752 penicillin binding . . . Aay33117 . . .  859d Seq. ID No. Seq. ID No. transport putative cation 1.00E−146 1771 1772 transporting P-ty . . . AF067954 . . .  866b Seq. ID No. Seq. ID No. membrane ATPase, Bacillus 1.00E−124 1785 1786 subtilis Bacteria; Firmicutes; GE . . .  868b Seq. ID No. Seq. ID No. transporter betaine ABC 1.00E−71 1789 1790 transporter permease and substrat, Lac . . .  870 Seq. ID No. Seq. ID No. transporter Pseudogene, similar 1.00E−80 1791 1792 to glycine-betaine bindin, Lis . . .  873c Seq. ID No. Seq. ID No. transporter Pseudogene, similar 2.00E−73 1797 1798 to glycine-betaine bindin, Lis . . .  878c Seq. ID No. Seq. ID No. hemolysin Alpha-hemolysin, 1.00E−20 1811 1812 Fusobacterium nucleatum subsp. nu . . .  880c Seq. ID No. Seq. ID No. response regulator putative response 5.00E−76 1817 1818 regulator, Lactobacillus sakei B . . .  885 Seq. ID No. Seq. ID No. response regulator putative histidine 1.00E−82 1819 1820 kinase, Lactobacillus sakei Bac . . .  886 Seq. ID No. Seq. ID No. penicillin D-alanine 4.00E−55 1821 1822 carboxypeptidase (PBP-5), Bacillus subti . . .  929b Seq. ID No. Seq. ID No. membrane PROBABLE 1.00E−117 1871 1872 BIFUNCTIONAL, Ralstonia solanacearum Bac . . .  939c Seq. ID No. Seq. ID No. transporter branch-chain amino 3.00E−64 1895 1896 acid transporter, Bacillus subt . . .  946 Seq. ID No. Seq. ID No. phosphatase deoxyuridine 5′- 3.00E−30 1905 1906 triphosphate nucleotidhydrolase, L . . .  949d Seq. ID No. Seq. ID No. PROTEASE PROBABLE ATP- 1.00E−101 1913 1914 DEPENDENT PROTEASE, . . . AL646064 . . .  951b Seq. ID No. Seq. ID No. transporter Pseudogene, similar 4.00E−76 1919 1920 to glycine-betaine bindin, Lis . . .  952b Seq. ID No. Seq. ID No. Membrane Membrane- 3.00E−68 1923 1924 associated protein containing a homolo, C . . .  972b Seq. ID No. Seq. ID No. phosphatase exopolyphosphatase, 3.00E−60 1965 1966 Bacillus halodurans Bacteria; . . .  977b Seq. ID No. Seq. ID No. lipoprotein PUTATIVE OUTER 1.00E−50 1971 1972 MEMBRANE LIPOPROTEIN, Sinorhizobium . . .  988d Seq. ID No. Seq. ID No. membrane putative conserved 3.00E−35 1999 2000 membrane protein, Listeria mono . . . 1016c Seq. ID No. Seq. ID No. transporter Na+ ABC transporter 1.00E−41 2047 2048 (ATP-binding protein), NATA, C . . . 1017d Seq. ID No. Seq. ID No. transporter Na+ ABC 2.00E−17 2055 2056 transporter, NATB, Clostridium acetobutyli . . . 1036c Seq. ID No. Seq. ID No. transporter Listeria 1.00E−126 2091 2092 monocytogenes Bacteria; Firmicutes; Bacil . . . 1037 Seq. ID No. Seq. ID No. transporter Glutamine ABC 1.00E−93 2093 2094 transporter (ATP- binding protein), C . . . 1047b Seq. ID No. Seq. ID No. adhesion YcdH, Bacillus 3.00E−35 2115 2116 subtilis Bacteria; Firmicutes; Baci . . . 1049b Seq. ID No. Seq. ID No. transporter Listeria innocua 8.00E−92 2119 2120 Bacteria; Firmicutes; Bacillus/Cl . . . 1050d Seq. ID No. Seq. ID No. membrane Listeria innocua 4.00E−71 2127 2128 Bacteria; Firmicutes; Bacillus/Cl . . . 1070b Seq. ID No. Seq. ID No. sporulation stage V sporulation 3.00E−47 2165 2166 protein C (peptidyl- tRN, Bacil . . . 1077e Seq. ID No. Seq. ID No. membrane Listeria innocua 3.00E−53 2179 2180 Bacteria; Firmicutes; Bacillus/Cl . . . 1094b Seq. ID No. Seq. ID No. membrane S. pneumoniae 0 2207 2208 putative ATPase involved in membrane . . . 1100 Seq. ID No. Seq. ID No. transporter probable ABC 9.00E−27 2223 2224 transporter, Clostridium perfringens . . . 1101b Seq. ID No. Seq. ID No. transporter ABC transporter 2.00E−15 2227 2228 ATP-binding protein, Xanthomonas a . . . 1111c Seq. ID No. Seq. ID No. membrane Listeria innocua 2.00E−49 2241 2242 Bacteria; Firmicutes; Bacillus/Cl . . . 1127 Seq. ID No. Seq. ID No. transporter ABC transporter 7.00E−35 2253 2254 ATP-binding protein, Clostridium a . . . 1135b Seq. ID No. Seq. ID No. lipoprotein putative lipoprotein, 5.00E−29 2263 2264 Streptomyces coelicolor A3(2 . . . 1138 Seq. ID No. Seq. ID No. capsular unknown, 9.00E−60 2269 2270 Staphylococcus aureus Bacteria; Firmicute . . . 1140c Seq. ID No. Seq. ID No. transport Listeria innocua 2.00E−85 2275 2276 Bacteria; Firmicutes; Bacillus/Cl . . . 1149 Seq. ID No. Seq. ID No. transporter putative ABC- 1.00E−106 2301 2302 transporter ATP- bind . . . AL627273 . . . 1152g Seq. ID No. Seq. ID No. transporter dipeptide ABC 1.00E−49 2315 2316 transporter, permease protei, Helico . . . 1155g Seq. ID No. Seq. ID No. transporter Staphylococcus 3.00E−80 2329 2330 aureus subsp. aureus MW2 Bacteria; . . . 1158b Seq. ID No. Seq. ID No. lipoprotein RGD-containing 2.00E−94 2333 2334 lipoprotein, Staphylococcus aureus . . . 1165 Seq. ID No. Seq. ID No. peptidoglycan peptidoglycan lytic 1.00E−29 2343 2344 protein P45, Listeria innocua . . . 1166 Seq. ID No. Seq. ID No. Response regulator Response regulator 1.00E−42 2345 2346 (CheY-like domain, HT, Clostrid . . . 1171c Seq. ID No. Seq. ID No. membrane ABC-type 1.00E−20 2363 2364 transmembrane transport protein, Campylob . . . 1177 Seq. ID No. Seq. ID No. capsular capsular 3.00E−11 2373 2374 polysaccharide biosynthesi . . . U67548 . . . 1180e Seq. ID No. Seq. ID No. wall unknown protein, 3.00E−66 2391 2392 Streptococcus mutans Bacteria; Fi . . . 1191 Seq. ID No. Seq. ID No. transporter putative ABC 3.00E−70 2417 2418 transporter (ATP- binding protein), St . . . 1197 Seq. ID No. Seq. ID No. Periplasmic Periplasmic serine 2.00E−37 2429 2430 proteases (ClpP class), Thermoa . . . 1214 Seq. ID No. Seq. ID No. protease Listeria innocua 4.00E−35 2465 2466 Bacteria; Firmicutes; Bacillus/Cl . . . 1218b Seq. ID No. Seq. ID No. protease glycoprotease family 1.00E−115 2475 2476 protein, Streptococcus pneumo . . . 1221b Seq. ID No. Seq. ID No. transporter hypothetical ABC 1.00E−155 2483 2484 transporter ATP- bindin, Staphyloc . . . 1233c Seq. ID No. Seq. ID No. transporter putative ATP-binding 6.00E−26 2513 2514 component of a transpor, Esch . . . 1237 Seq. ID No. Seq. ID No. wall YocH, Bacillus 4.00E−14 2525 2526 subtilis Bacteria; Firmicutes; Baci . . . 1258d Seq. ID No. Seq. ID No. transporter P-type ATPase - 1.00E−159 2589 2590 calcium transporter, Streptococcus . . . 1271 Seq. ID No. Seq. ID No. transporter Met, Streptococcus 4.00E−99 2613 2614 pneumoniae Bacteria; Firmicutes . . . 1288 Seq. ID No. Seq. ID No. membrane membrane bound 3.00E−42 2651 2652 protein, Bacillus subtilis Bacteria . . . 1300 Seq. ID No. Seq. ID No. transport secretory protein for 1.00E−121 2669 2670 transport of . . . X65961 . . . 1305c Seq. ID No. Seq. ID No. transporter cell division ABC 7.00E−81 2677 2678 transporter, ATP- bindin, Strepto . . . 1308e Seq. ID No. Seq. ID No. transporter cell division ABC 4.00E−47 2687 2688 transporter, permease protei, St . . . 1311 Seq. ID No. Seq. ID No. response regulator two-component 3.00E−79 2689 2690 response regulator involved i, Bacil . . . 1315 Seq. ID No. Seq. ID No. Membrane Membrane- 1.00E−36 2693 2694 associated sensory histi . . . AE007774 . . . 1319b Seq. ID No. Seq. ID No. membrane ABC transporter 7.00E−90 2703 2704 membrane-spanning permease , Strep . . . 1320c Seq. ID No. Seq. ID No. transmembrane phosphate ABC 1.00E−78 2709 2710 transporter, permease protein, Strep . . . 1322b Seq. ID No. Seq. ID No. transport Listeria 1.00E−29 2715 2716 monocytogenes Bacteria; Firmicutes; Bacil . . . 1344b Seq. ID No. Seq. ID No. lipoprotein putative HPr(ser) 8.00E−79 2751 2752 kinase, Streptococcus mutans Bac . . . 1348 Seq. ID No. Seq. ID No. lipoprotein Listeria 2.00E−66 2753 2754 monocytogenes Bacteria; Firmicutes; Bacil . . . 1355 Seq. ID No. Seq. ID No. Capsular Capsular 1.00E−103 2767 2768 polysaccharide of Streptoco . . . Aar83041 . . . 1366b Seq. ID No. Seq. ID No. protease protease ClpP, 1.00E−81 2787 2788 Listeria monocytogenes Bacteria; Fi . . . 1368 Seq. ID No. Seq. ID No. receptor plasmin receptor, 1.00E−100 2791 2792 Streptococcus pyogenes Bacteria; . . . 1377 Seq. ID No. Seq. ID No. iron enolase, 2.00E−66 2803 2804 Spironucleus vortens Euk . . . AF159517 . . . 1408 Seq. ID No. Seq. ID No. transporter ABC transporter, 1.00E−116 2867 2868 Lactobacillus plantarum Bacteria; . . . 1410 Seq. ID No. Seq. ID No. transport bacillus subtilis. 1.00E−39 2871 2872 hypothetical abc transporter at . . . 1426b Seq. ID No. Seq. ID No. polysaccharide Orfde2, 3.00E−24 2907 2908 Enterococcus faecalis Bacteria; Firmicutes . . . 1431 Seq. ID No. Seq. ID No. transporter Bacillus subtilis 1.00E−100 2919 2920 Bacteria; Firmicutes; Bacillus/C . . . 1432 Seq. ID No. Seq. ID No. transporter predicted membrane 3.00E−38 2921 2922 components of a, Thermoanaeroba . . . 1433 Seq. ID No. Seq. ID No. immunogenic Propionibacterium 1.00E−111 2923 2924 acnes immunogenic . . . Aau55208 . . . 1434b Seq. ID No. Seq. ID No. iron Bacillus subtilis 8.00E−37 2927 2928 Bacteria; Firmicutes; Bacillus/C . . . 1437c Seq. ID No. Seq. ID No. transporter ABC transporter 1.00E−102 2933 2934 subunit, Synechocys . . . D64004 . . . 1442b Seq. ID No. Seq. ID No. transporter ABC transporter 2.00E−47 2957 2958 (ATP-binding protein), Bacillus ha . . . 1451 Seq. ID No. Seq. ID No. transporter ABC transporter, 1.00E−23 2979 2980 ATP-binding protein, Streptococcu . . . 1457c Seq. ID No. Seq. ID No. transporter Na/Pi cotransporter 1.00E−118 2999 3000 II-related protein, Streptococ . . . 1462b Seq. ID No. Seq. ID No. transporter probable ABC 1.00E−111 3005 3006 transporter (ATP- binding protein), Ye . . . 1466d Seq. ID No. Seq. ID No. membrane ABC transporter 1.00E−115 3019 3020 ATP- binding/membrane spannin, Stre . . . 1470b Seq. ID No. Seq. ID No. membrane Integral membrane 2.00E−11 3031 3032 protein, Fusobacterium nucleatum . . . 1471 Seq. ID No. Seq. ID No. channel potassium channel 6.00E−20 3035 3036 protein, Methanosarcina acetivor . . . 1479c Seq. ID No. Seq. ID No. wall Listeria 2.00E−15 3055 3056 monocytogenes Bacteria; Firmicutes; Bacil . . . 1484c Seq. ID No. Seq. ID No. transporter magnesium (Mg2+) 2.00E−65 3067 3068 transporter, Bacillus halodurans . . . 1488g Seq. ID No. Seq. ID No. transporter Staphylococcus 2.00E−55 3085 3086 aureus subsp. aureus N315 Bacteria; . . . 1530b Seq. ID No. Seq. ID No. peptidoglycan Penicillin-binding 1.00E−120 3165 3166 protein 1b, Streptococcus pneum . . . 1543 Seq. ID No. Seq. ID No. invasion extracellular protein, 2.00E−26 3183 3184 Listeria welshimeri Bacteri . . . 1547b Seq. ID No. Seq. ID No. spore Bacillus subtilis 2.00E−71 3189 3190 Bacteria; Firmicutes; Bacillus/C . . . 1553b Seq. ID No. Seq. ID No. transporter putative ABC 3.00E−55 3197 3198 transporter subunit ComYA, Streptococ . . . 1556c Seq. ID No. Seq. ID No. transporter Na+ ABC transporter 1.00E−36 3211 3212 (ATP-binding protein), NATA, C . . . 1573 Seq. ID No. Seq. ID No. transporter ABC transporter, 2.00E−42 3251 3252 ATP-binding protein, Streptococcu . . . 1577b Seq. ID No. Seq. ID No. transport drug efflux ABC 7.00E−12 3257 3258 transporter, Streptococcus pneumon . . . 1578 Seq. ID No. Seq. ID No. transport ABC transporter, 7.00E−34 3259 3260 Lactobacillus helveticus Bacteria . . . 1594a Seq. ID No. Seq. ID No. transmembrane Chlamydia 9.00E−22 3297 3298 pneumoniae transmembrane p . . . Aay35379 . . . 1606b Seq. ID No. Seq. ID No. response regulator putative histidine 4.00E−69 3319 3320 protein kinase, Lactococcus lac . . . 1607b Seq. ID No. Seq. ID No. lipoprotein YqjG, Bacillus 7.00E−30 3323 3324 subtilis Bacteria; Firmicutes; Baci . . . 1616b Seq. ID No. Seq. ID No. sporulation Staphylococcus 1.00E−156 3335 3336 aureus subsp. aureus MW2 Bacteria; . . . 1619 Seq. ID No. Seq. ID No. lipoprotein CD4+ T cell- 4.00E−81 3337 3338 stimulating antigen, lipoprotein, List . . . 1625c Seq. ID No. Seq. ID No. transport putative sugar ABC 3.00E−76 3355 3356 transporter (permeas, Streptoco . . . 1626b Seq. ID No. Seq. ID No. membrane sugar ABC 7.00E−97 3359 3360 transporter, permease protein, Streptoco . . . 1634c Seq. ID No. Seq. ID No. peptidoglycan beta-1,4-N- 4.00E−34 3377 3378 acetylmuramoylhydro- lase, Enterococcus h . . . 1646e Seq. ID No. Seq. ID No. polysaccharide putative 3.00E−78 3397 3398 polysaccharide biosynthesis protein, Stre . . . 1649a Seq. ID No. Seq. ID No. penicillin Streptococcus 7.00E−35 3405 3406 thermophilus Bacteria; Firmicutes; G . . . 1654 Seq. ID No. Seq. ID No. immunogenic Propionibacterium 8.00E−24 3415 3416 acnes immunogenic . . . Aau49489 . . . 1659c Seq. ID No. Seq. ID No. membrane putative integral 2.00E−93 3425 3426 membrane protein, Campylobacter . . . 1660b Seq. ID No. Seq. ID No. membrane putative integral 1.00E−24 3427 3428 membrane protein, Campylobacter . . . 1674 Seq. ID No. Seq. ID No. membrane putative integral 9.00E−15 3461 3462 membrane protein, Campylobacter . . . 1675a Seq. ID No. Seq. ID No. immunogenic Propionibacterium 3.00E−24 3463 3464 acnes immunogenic . . . Aau47623 . . . 1685 Seq. ID No. Seq. ID No. immunogenic Propionibacterium 2.00E−50 3487 3488 acnes immunogenic . . . Aau58232 . . . 1688b Seq. ID No. Seq. ID No. polysaccharide Orfde3, 5.00E−87 3493 3494 Enterococcus faecalis Bacteria; Firmicutes . . . 1689a Seq. ID No. Seq. ID No. cps7H putative 5.00E−38 3497 3498 glycosyltransferase Cps7H, Streptococcus . . . 1691 Seq. ID No. Seq. ID No. membrane Hypothetical 6.00E−12 3507 3508 membrane-spanning protein, Fusobacter . . . 1694d Seq. ID No. Seq. ID No. membrane membrane bound 1.00E−68 3519 3520 protein, Bacillus subtilis Bacteria . . . 1696 Seq. ID No. Seq. ID No. transport UDP-Glc-6- 1.00E−155 3521 3522 dehydrogenase Ugd, Escherichia coli Bact . . . 1699b Seq. ID No. Seq. ID No. transport probable export 4.00E−28 3529 3530 protein, Escherichia coli K12 Bact . . . 1701a Seq. ID No. Seq. ID No. immunogenic Propionibacterium 4.00E−34 3535 3536 acnes immunogenic . . . Aau67497 . . . 1752b Seq. ID No. Seq. ID No. surface streptococcal 7.00E−14 3629 3630 surface protein, Streptococcus dysga . . . 1756b Seq. ID No. Seq. ID No. membrane hypothetical 1.00E−31 3635 3636 membrane protein LaaO, Lactobacillus . . . 1798c Seq. ID No. Seq. ID No. membrane Uncharacterized 1.00E−13 3727 3728 membrane protein, homolog o, Clost . . . 1808d Seq. ID No. Seq. ID No. membrane mbh8 NADH 7.00E−43 3759 3760 dehydrogenase subunit - integra, Pyrococ . . . 1809f Seq. ID No. Seq. ID No. membrane mbh8 NADH 2.00E−48 3771 3772 dehydrogenase subunit - integra, Pyrococ . . . 1816a Seq. ID No. Seq. ID No. peptidoglycan Penicillin-binding 1.00E−124 3793 3794 protein 1A, Streptococcus pneum . . . 1838b Seq. ID No. Seq. ID No. transport ABC-type 6.00E−57 3839 3840 multidrug/protein/lipid transpor, Thermoa . . . 1842b Seq. ID No. Seq. ID No. protease sac operon related 1.00E−22 3851 3852 regulation protein, Bacillus sp . . . 1845c Seq. ID No. Seq. ID No. channel voltage-gated 4.00E−63 3863 3864 chloride channel family protein, Str . . . 1848a Seq. ID No. Seq. ID No. membrane Integral membrane 6.00E−24 3865 3866 protein, Fusobacterium nucleatum . . . 1855 Seq. ID No. Seq. ID No. capsule Regulatory function 1.00E−13 3883 3884 on capsule ex . . . AE008458 . . . 1857c Seq. ID No. Seq. ID No. polysaccharide Staphylococcus 7.00E−15 3891 3892 aureus subsp. aureus N315 Bacteria; . . . 1865b Seq. ID No. Seq. ID No. membrane Listeria innocua 2.00E−40 3913 3914 Bacteria; Firmicutes; Bacillus/Cl . . . 1873c Seq. ID No. Seq. ID No. protease OrfRM1, Bacillus 8.00E−91 3925 3926 subtilis Bacteria; Firmicutes; GE . . . 1875c Seq. ID No. Seq. ID No. Signal ref|NP_655047.1| 1.00E−32 3929 3930 (NC_003995) Peptidase_S26, Signal . . . 1898b Seq. ID No. Seq. ID No. membrane Hypothetical 6.00E−32 3975 3976 membrane-spanning protein, Fusobacter . . . 1902a Seq. ID No. Seq. ID No. capsular DNA topoisomerase 0 3981 3982 IV subunit B, Streptococcus agal . . . 1931b Seq. ID No. Seq. ID No. transport transporter protein, 3.00E−22 4027 4028 Haemophilus influenzae Rd Bac . . . 1936 Seq. ID No. Seq. ID No. transport Bacillus subtilis 2.00E−18 4039 4040 Bacteria; Firmicutes; Bacillus/C . . . 1941b Seq. ID No. Seq. ID No. Membrane Membrane 6.00E−18 4061 4062 associated histidine kinase-lik, Clostrid . . . 1946b Seq. ID No. Seq. ID No. transport probable amino acid 2.00E−56 4073 4074 transport protein, Clostridium . . . 1951a Seq. ID No. Seq. ID No. membrane ABC-type 1.00E−137 4081 4082 multidrug/protein/lipid transpor, Clostri . . . 1958b Seq. ID No. Seq. ID No. membrane ABC transporter 8.00E−44 4103 4104 membrane-spanning permease, Strep . . . 1960c Seq. ID No. Seq. ID No. transport ABC transporter 3.00E−68 4111 4112 substrate-binding protein, Strept . . . 1973 Seq. ID No. Seq. ID No. peptidoglycan peptidoglycan N- 1.00E−15 4137 4138 acetylglucosamine deacetylase A, S . . . 2016c Seq. ID No. Seq. ID No. transport Listeria 2.00E−20 4225 4226 monocytogenes Bacteria; Firmicutes; Bacil . . . 2024b Seq. ID No. Seq. ID No. penicillin Listeria 1.00E−132 4247 4248 monocytogenes Bacteria; Firmicutes; Bacil . . . 2074b Seq. ID No. Seq. ID No. wall Bacillus subtilis 2.00E−26 4343 4344 Bacteria; Firmicutes; Bacillus/C . . . 2092 Seq. ID No. Seq. ID No. response regulator Hpk1, Streptococcus 2.00E−22 4379 4380 thermophilus Bacteria; Firmicu . . . 2096c Seq. ID No. Seq. ID No. transport Staphylococcus 1.00E−61 4389 4390 aureus subsp. aureus MW2 Bacteria; . . . 2140a Seq. ID No. Seq. ID No. protease Listeria innocua 6.00E−55 4469 4470 Bacteria; Firmicutes; Bacillus/Cl . . . 2142a Seq. ID No. Seq. ID No. phosphatidate putative 1.00E−11 4473 4474 phosphatidate cytidylyltransferas, Strept . . . 2146 Seq. ID No. Seq. ID No. lipoprotein Listeria innocua 1.00E−68 4481 4482 Bacteria; Firmicutes; Bacillus/Cl . . . 2147b Seq. ID No. Seq. ID No. transport Listeria 5.00E−41 4485 4486 monocytogenes Bacteria; Firmicutes; Bacil . . . 2150a Seq. ID No. Seq. ID No. immunogenic Propionibacterium 9.00E−15 4493 4494 acnes immunogenic protein #18988 . . . 2161c Seq. ID No. Seq. ID No. immunogenic Propionibacterium 5.00E−12 4529 4530 acnes immunogenic protein #20073 . . . 2219c Seq. ID No. Seq. ID No. membrane Conserved 4.00E−20 4643 4644 membrane protein, probabl, Clostridium a . . . 2249 Seq. ID No. Seq. ID No. transport oligopeptide ABC 1.00E−148 4705 4706 transporte, Bacillus halodurans B . . . 2253d Seq. ID No. Seq. ID No. transport oligopeptide ABC 1.00E−60 4713 4714 transporter (permease), Bacillus . . . 2255b Seq. ID No. Seq. ID No. transport oligopeptide ABC 8.00E−93 4717 4718 transporter (permease), Bacillus . . . 2300 Seq. ID No. Seq. ID No. transport H+-transporting ATP 2.00E−18 4813 4814 synthase, subunit K (atpK), Me . . . 2301 Seq. ID No. Seq. ID No. transport H+-transporting ATP 3.00E−43 4815 4816 synthase, subunit I (atpI), Py . . . 2307 Seq. ID No. Seq. ID No. membrane membrane 1.00E−55 4825 4826 permease OpuCD, Listeria monocytogenes Ba . . . 2308 Seq. ID No. Seq. ID No. transport Listeria innocua 5.00E−81 4827 4828 Bacteria; Firmicutes; Bacillus/Cl . . . 2309c Seq. ID No. Seq. ID No. transport membrane 9.00E−33 4833 4834 permease OpuCB, Listeria monocytogenes Ba . . . 2311 Seq. ID No. Seq. ID No. transport glycine 1.00E−109 4837 4838 betaine/carnitine/ choline AB, Staphylococc . . . 2317 Seq. ID No. Seq. ID No. immunogenic Propionibacterium 9.00E−17 4851 4852 acnes immunogenic protein #7465 . . . . 2324 Seq. ID No. Seq. ID No. immunogenic Propionibacterium 5.00E−18 4863 4864 acnes immunogenic protein #5020 . . . . 2329d Seq. ID No. Seq. ID No. membrane Listeria innocua 2.00E−72 4875 4876 Bacteria; Firmicutes; Bacillus/Cl . . . 2331 Seq. ID No. Seq. ID No. membrane Listeria 1.00E−28 4879 4880 monocytogenes Bacteria; Firmicutes; Bacil . . . 2338c Seq. ID No. Seq. ID No. membrane predicted membrane 1.00E−178 4893 4894 GTPase involved in stres, Therm . . . 2344 Seq. ID No. Seq. ID No. membrane dihydrolipoamide 1.00E−167 4901 4902 dehydrogenase component o, Staphy . . . 2357 Seq. ID No. Seq. ID No. sensor protein sensor protein 1.00E−47 4919 4920 kinase, Lactococcus lactis subsp. l . . . 2363b Seq. ID No. Seq. ID No. periplasmic predicted 4.00E−45 4931 4932 periplasmic solute- binding protein, Ther . . . 2376 Seq. ID No. Seq. ID No. virulence aspartate 1.00E−117 4959 4960 semialdehyde dehydrogenase, Staphylococc . . . 2377b Seq. ID No. Seq. ID No. virulence Staphylococcus 2.00E−87 4963 4964 aureus mutant P14C15 virulence gene . . . 2387 Seq. ID No. Seq. ID No. Transport Transporter, 9.00E−40 4985 4986 Fusobacterium nucleatum subsp. nuclea . . . 2452 Seq. ID No. Seq. ID No. sporulation alanine 1.00E−118 5113 5114 dehydrogenase, Bacillus subtilis Bacteria; . . . 2453 Seq. ID No. Seq. ID No. ferric Bacillus subtilis 5.00E−48 5115 5116 Bacteria; Firmicutes; Bacillus/C . . . 2455 Seq. ID No. Seq. ID No. ferric Bacillus subtilis 2.00E−76 5117 5118 Bacteria; Firmicutes; Bacillus/C . . . 2456d Seq. ID No. Seq. ID No. transport Bacillus subtilis 2.00E−54 5125 5126 Bacteria; Firmicutes; Bacillus/C . . . 2458g Seq. ID No. Seq. ID No. transporter ferrichrome ABC 2.00E−65 5141 5142 transporter (permease), Bacillus h . . . 2475c Seq. ID No. Seq. ID No. secreted protein Human secreted 1.00E−109 5183 5184 protein sequence enco . . . Aab34842 . . . 2485 Seq. ID No. Seq. ID No. wall cell division protein, 1.00E−114 5201 5202 Enterococcus faecalis Bacte . . . 2490 Seq. ID No. Seq. ID No. wall cell division protein, 5.00E−22 5205 5206 Enterococcus faecalis Bacte . . . 2495a Seq. ID No. Seq. ID No. penicillin MRAY, 6.00E−64 5213 5214 Staphylococcus aureus Bacteria; Firmicutes; . . . 2497b Seq. ID No. Seq. ID No. wall penicillin-binding 1.00E−116 5219 5220 protein, Enterococcus faecalis . . . 2520d Seq. ID No. Seq. ID No. phosphatase phosphoenolpyruvate- 0 5279 5280 protein phosphatase, Staphyloc . . . 2525a Seq. ID No. Seq. ID No. virulence Amino acid 3.00E−11 5285 5286 sequence of a virulence factor encoded . . . 2547c Seq. ID No. Seq. ID No. immunogenic Propionibacterium 2.00E−14 5331 5332 acnes immunogenic protein #22248 . . . 2564d Seq. ID No. Seq. ID No. transport carboxypeptidase, 1.00E−42 5381 5382 Bacillus subtilis Bacteria; Firm . . . 2568 Seq. ID No. Seq. ID No. transport ABC-type multidrug 2.00E−47 5389 5390 transport system, ATPas, Thermo . . . 2582a Seq. ID No. Seq. ID No. membrane ABC transporter 9.00E−66 5405 5406 membrane-spanning permease, Strep . . . 2585 Seq. ID No. Seq. ID No. transport ABC transporter 1.00E−148 5411 5412 ATP-binding protein - cobal, Strep . . . 2589 Seq. ID No. Seq. ID No. lipoprotein Chlamydia 1.00E−120 5419 5420 trachomatis lipoprotein se . . . Aay37627 . . . 2596 Seq. ID No. Seq. ID No. immunogenic Propionibacterium 2.00E−27 5433 5434 acnes immunogenic protein #4493 . . . . 2616c Seq. ID No. Seq. ID No. membrane Listeria innocua 1.00E−10 5463 5464 Bacteria; Firmicutes; Bacillus/Cl . . . 2617b Seq. ID No. Seq. ID No. transport putative ABC 9.00E−69 5477 5478 transporter (ATP- binding protein), St . . . 2623b Seq. ID No. Seq. ID No. wall Lactococcus lactis 2.00E−23 5491 5492 subsp. cremoris Bacteria; Firmi . . . 2628 Seq. ID No. Seq. ID No. transport Pseudogene, similar 2.00E−77 5509 5510 to glycine-betaine bindin, Lis . . . 2629b Seq. ID No. Seq. ID No. transport oligopeptide ABC 1.00E−149 5513 5514 transporte, Bacillus halodurans B . . . 2633d Seq. ID No. Seq. ID No. transport oligopeptide ABC 1.00E−149 5525 5526 transporte, Bacillus halodurans B . . . 2637a Seq. ID No. Seq. ID No. transport oligopeptide ABC 1.00E−140 5529 5530 transporte, Bacillus halodurans B . . . 2643b Seq. ID No. Seq. ID No. peptidoglycan Penicillin-binding 1.00E−143 5537 5538 protein 2a, Streptococcus pneum . . . 2659b Seq. ID No. Seq. ID No. hemolysin putative hemolysin, 5.00E−71 5567 5568 Streptococcus pyogenes MGAS823 . . . 2674b Seq. ID No. Seq. ID No. membrane putative integral 5.00E−21 5599 5600 membrane protei . . . AL162756 . . . 2680c Seq. ID No. Seq. ID No. virulence Staphylococcus 1.00E−160 5621 5622 aureus mutant P11C12 virulence gene . . . 2688c Seq. ID No. Seq. ID No. transport phosphotidylglycero 4.00E−43 5637 5638 phosphate synthase, Streptococc . . . 2723 Seq. ID No. Seq. ID No. membrane Uncharacterized 1.00E−13 5699 5700 membrane protein, homolog o, Clost . . . 2734c Seq. ID No. Seq. ID No. transport cation transporter, 9.00E−62 5723 5724 Lactococcus lactis subsp. lact . . . 2738c Seq. ID No. Seq. ID No. transport transporter, Bacillus 3.00E−21 5733 5734 halodurans Bacteria; Firmicu . . . 2748c Seq. ID No. Seq. ID No. transport conserved 5.00E−34 5761 5762 hypothetical protein, Thermotoga maritim . . . 2758d Seq. ID No. Seq. ID No. immunogenic Propionibacterium 3.00E−36 5791 5792 acnes immunogenic . . . Aau49434 . . . 2801b Seq. ID No. Seq. ID No. response regulator VanSB, 1.00E−21 5895 5896 Enterococcus faecalis Bacteria; Firmicutes; . . . 2805b Seq. ID No. Seq. ID No. transmembrane transmembrane 1.00E−130 5901 5902 protein Vexp3, Streptococcus pneumon . . . 2809 Seq. ID No. Seq. ID No. transport ABC transporter, 1.00E−63 5903 5904 ATP-binding protein Vexp2, Strept . . . 2810c Seq. ID No. Seq. ID No. membrane ABG transporter 1.00E−59 5909 5910 membrane-spanning permease - Pe, S . . . 2812 Seq. ID No. Seq. ID No. transport probable ABC 1.00E−102 5913 5914 transporter, Clostridium perfringens . . . 2816 Seq. ID No. Seq. ID No. transport Listeria innocua 5.00E−59 5919 5920 Bacteria; Firmicutes; Bacillus/Cl . . . 2818e Seq. ID No. Seq. ID No. transport amino acid ABC 2.00E−58 5929 5930 transporter permease protein, Lacto . . . 2822a Seq. ID No. Seq. ID No. membrane putative membrane 7.00E−27 5939 5940 protein, Salmonella enterica sub . . . 2856c Seq. ID No. Seq. ID No. transport heavy-metal 1.00E−131 6001 6002 transporting CPx- type ATPase, Methanot . . . 2881 Seq. ID No. Seq. ID No. surface surface protein (GW 4.00E−23 6043 6044 repeat) similar t, Listeria in . . . 2883d Seq. ID No. Seq. ID No. transport ABC transporter 1.00E−107 6053 6054 permease protein, Lactococcus lact . . . 2886b Seq. ID No. Seq. ID No. transport Listeria 5.00E−69 6057 6058 monocytogenes Bacteria; Firmicutes; Bacil . . . 2900b Seq. ID No. Seq. ID No. wall YojL, Bacillus subtilis 2.00E−15 6089 6090 Bacteria; Firmicutes; Baci . . . 2902 Seq. ID No. Seq. ID No. peptidoglycan beta-1,4-N- 2.00E−32 6095 6096 acetylmuramoylhydro- lase, Enterococcus h . . . 2906 Seq. ID No. Seq. ID No. immunoglobulin Streptococcus sp. 2.00E−17 6103 6104 G148 Bacteria; Firmicutes; Bacil . . . 2909d Seq. ID No. Seq. ID No. transmembrane Listeria innocua 1.00E−144 6111 6112 Bacteria; Firmicutes; Bacillus/Cl . . . 2913b Seq. ID No. Seq. ID No. response regulator putative histidine 1.00E−92 6117 6118 kinase, Lactobacillus sakei Bac . . . 2931c Seq. ID No. Seq. ID No. transport putative 8.00E−96 6165 6166 sodium/glucose cotransporter, Salmonella . . . 2933b Seq. ID No. Seq. ID No. immunogenic Propionibacterium 1.00E−19 6169 6170 acnes immunogenic protein #6411 . . . . 2941b Seq. ID No. Seq. ID No. transport probable ABC 1.00E−145 6185 6186 transporter, Clostridium perfringens . . . 2943b Seq. ID No. Seq. ID No. transport ABC transporter 1.00E−114 6191 6192 ATP binding protein, Lactococcus l . . . 2948d Seq. ID No. Seq. ID No. membrane Listeria innocua 4.00E−56 6209 6210 Bacteria; Firmicutes; Bacillus/Cl . . . 2955e Seq. ID No. Seq. ID No. membrane putative integral 4.00E−35 6229 6230 membrane transporter protein, Si . . . 2965c Seq. ID No. Seq. ID No. hemolysin hemolysin, 1E−55 6257 6258 Treponema denticola Bact . . . U30249 . . . 2969 Seq. ID No. Seq. ID No. Membrane Membrane-fusion 5.00E−23 6263 6264 protein, Thermoanaerobacter tengco . . . 2971b Seq. ID No. Seq. ID No. lipoprotein ABC-type transport 5.00E−72 6271 6272 systems, involved i, Thermoanae . . . 2974b Seq. ID No. Seq. ID No. lipoprotein ABC-type transport 4.00E−61 6275 6276 systems, involved i, Thermoanae . . . 2980a Seq. ID No. Seq. ID No. transport unknown, 5.00E−13 6289 6290 Pasteurella multocida Bacteria; Proteobac . . . 2986b Seq. ID No. Seq. ID No. transport rnfD protein, 3.00E−28 6303 6304 Pseudomonas stutzeri A15 Bacteria; P . . . 3016b Seq. ID No. Seq. ID No. membrane ABC transporter 3.00E−27 6365 6366 membrane-spanning permease - Na, S . . . 3017 Seq. ID No. Seq. ID No. transporter ABC transporter 6.00E−82 6369 6370 ATP binding protein, Lactococcus l . . . 3024a Seq. ID No. Seq. ID No. virulence Amino acid 2.00E−13 6383 6384 sequence of a virulence factor encoded . . . 3037a Seq. ID No. Seq. ID No. lipoprotein putative host cell 8.00E−13 6415 6416 surface-exposed lipoprotein, St . . .

Listed in Table 9 are 242 ORFs that share some homology with the ORFs predicted by proteomic methods used for studying surface exposed proteins of Streptococcus pneumoniae. TABLE 9 PROTEOMICS ORF Number DNA SEQ ID Number Protein SEQ ID Number   1 Seq. ID No. 1 Seq. ID No. 2   2b Seq. ID No. 5 Seq. ID No. 6  56b Seq. ID No. 93 Seq. ID No. 94  57a Seq. ID No. 95 Seq. ID No. 96  60b Seq. ID No. 103 Seq. ID No. 104  62a Seq. ID No. 107 Seq. ID No. 108  85c Seq. ID No. 157 Seq. ID No. 158  112b Seq. ID No. 223 Seq. ID No. 224  114 Seq. ID No. 225 Seq. ID No. 226  121 Seq. ID No. 233 Seq. ID No. 234  124c Seq. ID No. 239 Seq. ID No. 240  129c Seq. ID No. 253 Seq. ID No. 254  157b Seq. ID No. 317 Seq. ID No. 318  158b Seq. ID No. 321 Seq. ID No. 322  165a Seq. ID No. 341 Seq. ID No. 342  167 Seq. ID No. 345 Seq. ID No. 346  171b Seq. ID No. 353 Seq. ID No. 354  175 Seq. ID No. 361 Seq. ID No. 362  176 Seq. ID No. 363 Seq. ID No. 364  177a Seq. ID No. 365 Seq. ID No. 366  180b Seq. ID No. 375 Seq. ID No. 376  184 Seq. ID No. 379 Seq. ID No. 380  186 Seq. ID No. 383 Seq. ID No. 384  188 Seq. ID No. 389 Seq. ID No. 390  189b Seq. ID No. 391 Seq. ID No. 392  192b Seq. ID No. 397 Seq. ID No. 398  195 Seq. ID No. 405 Seq. ID No. 406  197a Seq. ID No. 409 Seq. ID No. 410  198b Seq. ID No. 415 Seq. ID No. 416  203 Seq. ID No. 423 Seq. ID No. 424  204 Seq. ID No. 425 Seq. ID No. 426  205 Seq. ID No. 427 Seq. ID No. 428  206 Seq. ID No. 429 Seq. ID No. 430  208b Seq. ID No. 435 Seq. ID No. 436  210 Seq. ID No. 437 Seq. ID No. 438  211 Seq. ID No. 439 Seq. ID No. 440  213 Seq. ID No. 441 Seq. ID No. 442  215a Seq. ID No. 443 Seq. ID No. 444  218 Seq. ID No. 445 Seq. ID No. 446  219 Seq. ID No. 447 Seq. ID No. 448  220a Seq. ID No. 449 Seq. ID No. 450  226b Seq. ID No. 461 Seq. ID No. 462  227 Seq. ID No. 463 Seq. ID No. 464  228a Seq. ID No. 465 Seq. ID No. 466  249a Seq. ID No. 513 Seq. ID No. 514  262 Seq. ID No. 543 Seq. ID No. 544  265 Seq. ID No. 551 Seq. ID No. 552  267b Seq. ID No. 553 Seq. ID No. 554  269a Seq. ID No. 559 Seq. ID No. 560  284a Seq. ID No. 595 Seq. ID No. 596  286a Seq. ID No. 601 Seq. ID No. 602  311 Seq. ID No. 637 Seq. ID No. 638  315 Seq. ID No. 649 Seq. ID No. 650  318a Seq. ID No. 657 Seq. ID No. 658  321 Seq. ID No. 669 Seq. ID No. 670  324 Seq. ID No. 675 Seq. ID No. 676  329 Seq. ID No. 683 Seq. ID No. 684  351 Seq. ID No. 753 Seq. ID No. 754  429b Seq. ID No. 929 Seq. ID No. 930  450a Seq. ID No. 969 Seq. ID No. 970  473 Seq. ID No. 1041 Seq. ID No. 1042  474 Seq. ID No. 1043 Seq. ID No. 1044  498a Seq. ID No. 1085 Seq. ID No. 1086  499a Seq. ID No. 1089 Seq. ID No. 1090  500 Seq. ID No. 1093 Seq. ID No. 1094  502c Seq. ID No. 1097 Seq. ID No. 1098  504 Seq. ID No. 1099 Seq. ID No. 1100  505a Seq. ID No. 1101 Seq. ID No. 1102  543a Seq. ID No. 1175 Seq. ID No. 1176  551 Seq. ID No. 1205 Seq. ID No. 1206  570b Seq. ID No. 1237 Seq. ID No. 1238  687 Seq. ID No. 1459 Seq. ID No. 1460  709 Seq. ID No. 1495 Seq. ID No. 1496  710 Seq. ID No. 1497 Seq. ID No. 1498  715a Seq. ID No. 1503 Seq. ID No. 1504  722c Seq. ID No. 1517 Seq. ID No. 1518  726 Seq. ID No. 1527 Seq. ID No. 1528  728b Seq. ID No. 1531 Seq. ID No. 1532  730d Seq. ID No. 1539 Seq. ID No. 1540  732 Seq. ID No. 1543 Seq. ID No. 1544  738c Seq. ID No. 1549 Seq. ID No. 1550  747 Seq. ID No. 1573 Seq. ID No. 1574  792 Seq. ID No. 1657 Seq. ID No. 1658  829a Seq. ID No. 1709 Seq. ID No. 1710  859b Seq. ID No. 1767 Seq. ID No. 1768  866b Seq. ID No. 1785 Seq. ID No. 1786  886 Seq. ID No. 1821 Seq. ID No. 1822  938 Seq. ID No. 1889 Seq. ID No. 1890  954 Seq. ID No. 1925 Seq. ID No. 1926  977a Seq. ID No. 1969 Seq. ID No. 1970  992 Seq. ID No. 2003 Seq. ID No. 2004 1016c Seq. ID No. 2047 Seq. ID No. 2048 1033a Seq. ID No. 2075 Seq. ID No. 2076 1036b Seq. ID No. 2089 Seq. ID No. 2090 1037 Seq. ID No. 2093 Seq. ID No. 2094 1049a Seq. ID No. 2117 Seq. ID No. 2118 1058 Seq. ID No. 2137 Seq. ID No. 2138 1062 Seq. ID No. 2143 Seq. ID No. 2144 1094a Seq. ID No. 2205 Seq. ID No. 2206 1108b Seq. ID No. 2235 Seq. ID No. 2236 1131 Seq. ID No. 2257 Seq. ID No. 2258 1149 Seq. ID No. 2301 Seq. ID No. 2302 1171c Seq. ID No. 2363 Seq. ID No. 2364 1194 Seq. ID No. 2423 Seq. ID No. 2424 1205 Seq. ID No. 2445 Seq. ID No. 2446 1208 Seq. ID No. 2451 Seq. ID No. 2452 1221a Seq. ID No. 2481 Seq. ID No. 2482 1226 Seq. ID No. 2495 Seq. ID No. 2496 1230 Seq. ID No. 2505 Seq. ID No. 2506 1256 Seq. ID No. 2577 Seq. ID No. 2578 1258c Seq. ID No. 2587 Seq. ID No. 2588 1271 Seq. ID No. 2613 Seq. ID No. 2614 1281 Seq. ID No. 2633 Seq. ID No. 2634 1288 Seq. ID No. 2651 Seq. ID No. 2652 1297a Seq. ID No. 2665 Seq. ID No. 2666 1300 Seq. ID No. 2669 Seq. ID No. 2670 1305c Seq. ID No. 2677 Seq. ID No. 2678 1308e Seq. ID No. 2687 Seq. ID No. 2688 1315 Seq. ID No. 2693 Seq. ID No. 2694 1318 Seq. ID No. 2699 Seq. ID No. 2700 1321 Seq. ID No. 2711 Seq. ID No. 2712 1322b Seq. ID No. 2715 Seq. ID No. 2716 1349b Seq. ID No. 2757 Seq. ID No. 2758 1368 Seq. ID No. 2791 Seq. ID No. 2792 1371 Seq. ID No. 2793 Seq. ID No. 2794 1377 Seq. ID No. 2803 Seq. ID No. 2804 1408 Seq. ID No. 2867 Seq. ID No. 2868 1431 Seq. ID No. 2919 Seq. ID No. 2920 1437a Seq. ID No. 2929 Seq. ID No. 2930 1462b Seq. ID No. 3005 Seq. ID No. 3006 1466d Seq. ID No. 3019 Seq. ID No. 3020 1508 Seq. ID No. 3125 Seq. ID No. 3126 1512 Seq. ID No. 3137 Seq. ID No. 3138 1528 Seq. ID No. 3161 Seq. ID No. 3162 1537 Seq. ID No. 3179 Seq. ID No. 3180 1573 Seq. ID No. 3251 Seq. ID No. 3252 1578 Seq. ID No. 3259 Seq. ID No. 3260 1588 Seq. ID No. 3285 Seq. ID No. 3286 1600a Seq. ID No. 3309 Seq. ID No. 3310 1606a Seq. ID No. 3317 Seq. ID No. 3318 1619 Seq. ID No. 3337 Seq. ID No. 3338 1623b Seq. ID No. 3345 Seq. ID No. 3346 1626b Seq. ID No. 3359 Seq. ID No. 3360 1680 Seq. ID No. 3475 Seq. ID No. 3476 1694b Seq. ID No. 3515 Seq. ID No. 3516 1696 Seq. ID No. 3521 Seq. ID No. 3522 1759 Seq. ID No. 3641 Seq. ID No. 3642 1788c Seq. ID No. 3695 Seq. ID No. 3696 1816a Seq. ID No. 3793 Seq. ID No. 3794 1861b Seq. ID No. 3901 Seq. ID No. 3902 1875b Seq. ID No. 3927 Seq. ID No. 3928 1912 Seq. ID No. 3987 Seq. ID No. 3988 1918c Seq. ID No. 4001 Seq. ID No. 4002 1940 Seq. ID No. 4057 Seq. ID No. 4058 1951a Seq. ID No. 4081 Seq. ID No. 4082 1960c Seq. ID No. 4111 Seq. ID No. 4112 1967 Seq. ID No. 4125 Seq. ID No. 4126 1996 Seq. ID No. 4193 Seq. ID No. 4194 2000 Seq. ID No. 4195 Seq. ID No. 4196 2020 Seq. ID No. 4237 Seq. ID No. 4238 2024b Seq. ID No. 4247 Seq. ID No. 4248 2094 Seq. ID No. 4383 Seq. ID No. 4384 2097 Seq. ID No. 4393 Seq. ID No. 4394 2100 Seq. ID No. 4397 Seq. ID No. 4398 2104 Seq. ID No. 4401 Seq. ID No. 4402 2117 Seq. ID No. 4435 Seq. ID No. 4436 2125a Seq. ID No. 4449 Seq. ID No. 4450 2140b Seq. ID No. 4471 Seq. ID No. 4472 2149b Seq. ID No. 4491 Seq. ID No. 4492 2156c Seq. ID No. 4511 Seq. ID No. 4512 2160b Seq. ID No. 4519 Seq. ID No. 4520 2164 Seq. ID No. 4531 Seq. ID No. 4532 2174 Seq. ID No. 4549 Seq. ID No. 4550 2185 Seq. ID No. 4577 Seq. ID No. 4578 2186b Seq. ID No. 4581 Seq. ID No. 4582 2189b Seq. ID No. 4585 Seq. ID No. 4586 2203 Seq. ID No. 4609 Seq. ID No. 4610 2204 Seq. ID No. 4611 Seq. ID No. 4612 2206a Seq. ID No. 4613 Seq. ID No. 4614 2234a Seq. ID No. 4675 Seq. ID No. 4676 2238 Seq. ID No. 4685 Seq. ID No. 4686 2256 Seq. ID No. 4719 Seq. ID No. 4720 2260c Seq. ID No. 4729 Seq. ID No. 4730 2269 Seq. ID No. 4743 Seq. ID No. 4744 2275b Seq. ID No. 4755 Seq. ID No. 4756 2284 Seq. ID No. 4781 Seq. ID No. 4782 2286b Seq. ID No, 4787 Seq. ID No. 4788 2311 Seq. ID No. 4837 Seq. ID No. 4838 2312b Seq. ID No. 4841 Seq. ID No. 4842 2316 Seq. ID No. 4849 Seq. ID No. 4850 2321a Seq. ID No. 4855 Seq. ID No. 4856 2338a Seq. ID No. 4889 Seq. ID No. 4890 2344 Seq. ID No. 4901 Seq. ID No. 4902 2353 Seq. ID No. 4915 Seq. ID No. 4916 2354 Seq. ID No. 4917 Seq. ID No. 4918 2363b Seq. ID No. 4931 Seq. ID No. 4932 2365b Seq. ID No. 4935 Seq. ID No. 4936 2384a Seq. ID No. 4977 Seq. ID No. 4978 2409a Seq. ID No. 5025 Seq. ID No. 5026 2410 Seq. ID No. 5029 Seq. ID No. 5030 2449b Seq. ID No. 5109 Seq. ID No. 5110 2453 Seq. ID No. 5115 Seq. ID No. 5116 2455 Seq. ID No. 5117 Seq. ID No. 5118 2465a Seq. ID No. 5155 Seq. ID No. 5156 2477 Seq. ID No. 5185 Seq. ID No. 5186 2485 Seq. ID No. 5201 Seq. ID No. 5202 2489 Seq. ID No. 5203 Seq. ID No. 5204 2497b Seq. ID No. 5219 Seq. ID No. 5220 2516b Seq. ID No. 5261 Seq. ID No. 5262 2527a Seq. ID No. 5289 Seq. ID No. 5290 2528b Seq. ID No. 5295 Seq. ID No. 5296 2564b Seq. ID No. 5377 Seq. ID No. 5378 2568 Seq. ID No. 5389 Seq. ID No. 5390 2578 Seq. ID No. 5399 Seq. ID No. 5400 2585 Seq. ID No. 5411 Seq. ID No. 5412 2643b Seq. ID No. 5537 Seq. ID No. 5538 2680c Seq. ID No. 5621 Seq. ID No. 5622 2684a Seq. ID No. 5627 Seq. ID No. 5628 2695 Seq. ID No. 5657 Seq. ID No. 5658 2716a Seq. ID No. 5675 Seq. ID No. 5676 2732 Seq. ID No. 5717 Seq. ID No. 5718 2752 Seq. ID No. 5777 Seq. ID No. 5778 2785b Seq. ID No. 5859 Seq. ID No. 5860 2805b Seq. ID No. 5901 Seq. ID No. 5902 2812 Seq. ID No. 5913 Seq. ID No. 5914 2816 Seq. ID No. 5919 Seq. ID No. 5920 2818c Seq. ID No. 5925 Seq. ID No. 5926 2820 Seq. ID No. 5933 Seq. ID No. 5934 2886a Seq. ID No. 6055 Seq. ID No. 6056 2918 Seq. ID No. 6129 Seq. ID No. 6130 2921 Seq. ID No. 6133 Seq. ID No. 6134 2941c Seq. ID No. 6187 Seq. ID No. 6188 2943c Seq. ID No. 6193 Seq. ID No. 6194 2954 Seq. ID No. 6219 Seq. ID No. 6220 2971b Seq. ID No. 6271 Seq. ID No. 6272 2975 Seq. ID No. 6277 Seq. ID No. 6278 3017 Seq. ID No. 6369 Seq. ID No. 6370 3020 Seq. ID No. 6375 Seq. ID No. 6376 3022 Seq. ID No. 6379 Seq. ID No. 6380 3026b Seq. ID No. 6389 Seq. ID No. 6390 3118b Seq. ID No. 6591 Seq. ID No. 6592 3121 Seq. ID No. 6605 Seq. ID No. 6606

Listed in Table 10 are 22 ORFs predicted to be covalently bound to the peptidoglycan region via the ‘LPXTG’ motif. These ORFs were found using the HMM LPXTG motif finder and are classified as proteins that might be targeted by sortase. The Applicants developed a HMM using approximately 70 known prokaryotic polypeptides containing the LPXTG cell wall sorting signal. This HMM was used to predict cell wall polypeptides that are anchored to the peptidoglycan layer. TABLE 10 LPXTG MOTIF ORF Number DNA SEQ ID Number Protein SEQ ID Number  246a Seq. ID No. 503 Seq. ID No. 504  246b Seq. ID No. 505 Seq. ID No. 506  609a Seq. ID No. 1315 Seq. ID No. 1316  609b Seq. ID No. 1317 Seq. ID No. 1318  631a Seq. ID No. 1363 Seq. ID No. 1364  631b Seq. ID No. 1365 Seq. ID No. 1366  631c Seq. ID No. 1367 Seq. ID No. 1368  631d Seq. ID No. 1369 Seq. ID No. 1370  743a Seq. ID No. 1559 Seq. ID No. 1560  743b Seq. ID No. 1561 Seq. ID No. 1562  751 Seq. ID No. 1581 Seq. ID No. 1582  847a Seq. ID No. 1739 Seq. ID No. 1740  847b Seq. ID No. 1741 Seq. ID No. 1742 1381a Seq. ID No. 2811 Seq. ID No. 2812 1381b Seq. ID No. 2813 Seq. ID No. 2814 1747 Seq. ID No. 3619 Seq. ID No. 3620 2669a Seq. ID No. 5587 Seq. ID No. 5588 2669b Seq. ID No. 5589 Seq. ID No. 5590 2669c Seq. ID No. 5591 Seq. ID No. 5592 2757a Seq. ID No. 5781 Seq. ID No. 5782 2757b Seq. ID No. 5783 Seq. ID No. 5784 2906 Seq. ID No. 6103 Seq. ID No. 6104

Listed in Table 11 are 71 ORFs predicted to be lipoproteins based on the HMM Lipo program. TABLE 11 LIPOPROTEIN ORF Number DNA SEQ ID Number Protein SEQ ID Number  38a Seq. ID No. 45 Seq. ID No. 46  38b Seq. ID No. 47 Seq. ID No. 48  91a Seq. ID No. 171 Seq. ID No. 172  114 Seq. ID No. 225 Seq. ID No. 226  201a Seq. ID No. 419 Seq. ID No. 420  249a Seq. ID No. 513 Seq. ID No. 514  277c Seq. ID No. 575 Seq. ID No. 576  283a Seq. ID No. 591 Seq. ID No. 592  283b Seq. ID No. 593 Seq. ID No. 594  318a Seq. ID No. 657 Seq. ID No. 658  318b Seq. ID No. 659 Seq. ID No. 660  321 Seq. ID No. 669 Seq. ID No. 670  324 Seq. ID No. 675 Seq. ID No. 676  349b Seq. ID No. 745 Seq. ID No. 746  349c Seq. ID No. 747 Seq. ID No. 748  431 Seq. ID No. 935 Seq. ID No. 936  476 Seq. ID No. 1045 Seq. ID No. 1046  492 Seq. ID No. 1075 Seq. ID No. 1076  524b Seq. ID No. 1137 Seq. ID No. 1138  542 Seq. ID No. 1173 Seq. ID No. 1174  546b Seq. ID No. 1191 Seq. ID No. 1192  546c Seq. ID No. 1193 Seq. ID No. 1194  547a Seq. ID No. 1195 Seq. ID No. 1196  744 Seq. ID No. 1563 Seq. ID No. 1564  794b Seq. ID No. 1661 Seq. ID No. 1662  794c Seq. ID No. 1663 Seq. ID No. 1664  794d Seq. ID No. 1665 Seq. ID No. 1666  870 Seq. ID No. 1791 Seq. ID No. 1792  873c Seq. ID No. 1797 Seq. ID No. 1798  951a Seq. ID No. 1917 Seq. ID No. 1918  977a Seq. ID No. 1969 Seq. ID No. 1970 1047b Seq. ID No. 2115 Seq. ID No. 2116 1067 Seq. ID No. 2159 Seq. ID No. 2160 1197 Seq. ID No. 2429 Seq. ID No. 2430 1239 Seq. ID No. 2527 Seq. ID No. 2528 1318 Seq. ID No. 2699 Seq. ID No. 2700 1382 Seq. ID No. 2815 Seq. ID No. 2816 1411b Seq. ID No. 2875 Seq. ID No. 2876 1449a Seq. ID No. 2975 Seq. ID No. 2976 1449b Seq. ID No. 2977 Seq. ID No. 2978 1455b Seq. ID No. 2991 Seq. ID No. 2992 1475 Seq. ID No. 3043 Seq. ID No. 3044 1607b Seq. ID No. 3323 Seq. ID No. 3324 1619 Seq. ID No. 3337 Seq. ID No. 3338 1970b Seq. ID No. 4133 Seq. ID No. 4134 1973 Seq. ID No. 4137 Seq. ID No. 4138 2146 Seq. ID No. 4481 Seq. ID No. 4482 2249 Seq. ID No. 4705 Seq. ID No. 4706 2308 Seq. ID No. 4827 Seq. ID No. 4828 2329a Seq. ID No. 4869 Seq. ID No. 4870 2453 Seq. ID No. 5115 Seq. ID No. 5116 2564b Seq. ID No. 5377 Seq. ID No. 5378 2564c Seq. ID No. 5379 Seq. ID No. 5380 2623b Seq. ID No. 5491 Seq. ID No. 5492 2628 Seq. ID No. 5509 Seq. ID No. 5510 2629b Seq. ID No. 5513 Seq. ID No. 5514 2633d Seq. ID No. 5525 Seq. ID No. 5526 2637a Seq. ID No. 5529 Seq. ID No. 5530 2637b Seq. ID No. 5531 Seq. ID No. 5532 2799a Seq. ID No. 5889 Seq. ID No. 5890 2810c Seq. ID No. 5909 Seq. ID No. 5910 2869b Seq. ID No. 6025 Seq. ID No. 6026 2869c Seq. ID No. 6027 Seq. ID No. 6028 2900a Seq. ID No. 6087 Seq. ID No. 6088 2900b Seq. ID No. 6089 Seq. ID No. 6090 2993a Seq. ID No. 6325 Seq. ID No. 6326 2993b Seq. ID No. 6327 Seq. ID No. 6328 3037a Seq. ID No. 6415 Seq. ID No. 6416 3145b Seq. ID No. 6637 Seq. ID No. 6638 3145c Seq. ID No. 6639 Seq. ID No. 6640 3147c Seq. ID No. 6645 Seq. ID No. 6646

Listed in Table 12 are ORFs encoding polypeptides predicted to be noncovalently bound to the peptidoglycan layer based on the HMM program. Four ORFs were identified that were predicted to encode proteins that bound peptidoglycans noncovalently. TABLE 12 PEPTIDOGLYCAN BINDING ORF Number DNA SEQ ID Number Protein SEQ ID Number 1733 Seq. ID No. 3589 Seq. ID No. 3590 1912 Seq. ID No. 3987 Seq. ID No. 3988 2497b Seq. ID No. 5219 Seq. ID No. 5220 2549 Seq. ID No. 5337 Seq. ID No. 5338

Also contemplated in the present invention are other important characteristics of Alloiococcus otitidis ORFs. For example, the Alloiococcus otitidis ORFs were searched to identify any that encode polypeptides with RGD motifs. Proteins that contain the Arg-Gly-Asp (RGD) attachment motif, together with integrins that serve as their receptor, constitute a major recognition system for cell adhesion, and thus are putative Alloiococcus otitidis polypeptide antigens. RGD recognition is one mechanism used by microbes to gain entry into eukaryotic tissues (Stockbauer et al., 1999; Isberg and Nhieu, 1994). However, not all RGD-containing proteins mediate cell attachment. It has been shown that RGD-containing peptides with a proline at the carboxy end (RGDP) are inactive in cell attachment assays (Pierschbacher and Rouslahti, 1987) and were excluded from consideration.

Listed in Table 13 are 125 ORFs found to contain the peptide sequence ‘RGDX’ where X is not proline. These ORFs are predicted to be surface localized and may interact with eukaryotic extracellular proteins. TABLE 13 RGD MOTIF ORF Number DNA SEQ ID Number Protein SEQ ID Number  24 Seq. ID No. 37 Seq. ID No. 38  58 Seq. ID No. 99 Seq. ID No. 100  62a Seq. ID No. 107 Seq. ID No. 108  62b Seq. ID No. 109 Seq. ID No. 110  62c Seq. ID No. 111 Seq. ID No. 112  171a Seq. ID No. 351 Seq. ID No. 352  171b Seq. ID No. 353 Seq. ID No. 354  228a Seq. ID No. 465 Seq. ID No. 466  228b Seq. ID No. 467 Seq. ID No. 468  228c Seq. ID No. 469 Seq. ID No. 470  228d Seq. ID No. 471 Seq. ID No. 472  329 Seq. ID No. 683 Seq. ID No. 684  383a Seq. ID No. 821 Seq. ID No. 822  383b Seq. ID No. 823 Seq. ID No. 824  467a Seq. ID No. 1021 Seq. ID No. 1022  467b Seq. ID No. 1023 Seq. ID No. 1024  535 Seq. ID No. 1157 Seq. ID No. 1158  536 Seq. ID No. 1159 Seq. ID No. 1160  569 Seq. ID No. 1233 Seq. ID No. 1234  614a Seq. ID No: 1333 Seq. ID No. 1334  614b Seq. ID No. 1335 Seq. ID No. 1336  680 Seq. ID No. 1449 Seq. ID No. 1450  743a Seq. ID No. 1559 Seq. ID No. 1560  743b Seq. ID No. 1561 Seq. ID No. 1562  744 Seq. ID No. 1563 Seq. ID No. 1564  774 Seq. ID No. 1625 Seq. ID No. 1626  863 Seq. ID No. 1777 Seq. ID No. 1778  890a Seq. ID No. 1827 Seq. ID No. 1828  890b Seq. ID No. 1829 Seq. ID No. 1830  929b Seq. ID No. 1871 Seq. ID No. 1872  954 Seq. ID No. 1925 Seq. ID No. 1926 1057 Seq. ID No. 2135 Seq. ID No. 2136 1063 Seq. ID No. 2145 Seq. ID No. 2146 1077b Seq. ID No. 2173 Seq. ID No. 2174 1077c Seq. ID No. 2175 Seq. ID No. 2176 1077d Seq. ID No. 2177 Seq. ID No. 2178 1077e Seq. ID No. 2179 Seq. ID No. 2180 1132 Seq. ID No. 2259 Seq. ID No. 2260 1155a Seq. ID No. 2317 Seq. ID No. 2318 1155b Seq. ID No. 2319 Seq. ID No. 2320 1155c Seq. ID No. 2321 Seq. ID No. 2322 1155d Seq. ID No. 2323 Seq. ID No. 2324 1155e Seq. ID No. 2325 Seq. ID No. 2326 1155f Seq. ID No. 2327 Seq. ID No. 2328 1155g Seq. ID No. 2329 Seq. ID No. 2330 1184 Seq. ID No. 2401 Seq. ID No. 2402 1302 Seq. ID No. 2671 Seq. ID No. 2672 1405 Seq. ID No. 2863 Seq. ID No. 2864 1409 Seq. ID No. 2869 Seq. ID No. 2870 1431 Seq. ID No. 2919 Seq. ID No. 2920 1432 Seq. ID No. 2921 Seq. ID No. 2922 1456 Seq. ID No. 2993 Seq. ID No. 2994 1489 Seq. ID No. 3087 Seq. ID No. 3088 1512 Seq. ID No. 3137 Seq. ID No. 3138 1587a Seq. ID No. 3279 Seq. ID No. 3280 1587b Seq. ID No. 3281 Seq. ID No. 3282 1587c Seq. ID No. 3283 Seq. ID No. 3284 1616a Seq. ID No. 3333 Seq. ID No. 3334 1616b Seq. ID No. 3335 Seq. ID No. 3336 1689a Seq. ID No. 3497 Seq. ID No. 3498 1689b Seq. ID No. 3499 Seq. ID No. 3500 1689c Seq. ID No. 3501 Seq. ID No. 3502 1700b Seq. ID No. 3533 Seq. ID No. 3534 1775a Seq. ID No. 3671 Seq. ID No. 3672 1775b Seq. ID No. 3673 Seq. ID No. 3674 1775c Seq. ID No. 3675 Seq. ID No. 3676 1838a Seq. ID No. 3837 Seq. ID No. 3838 1838b Seq. ID No. 3839 Seq. ID No. 3840 1838c Seq. ID No. 3841 Seq. ID No. 3842 1838d Seq. ID No. 3843 Seq. ID No. 3844 1875c Seq. ID No. 3929 Seq. ID No. 3930 1895 Seq. ID No. 3961 Seq. ID No. 3962 1934 Seq. ID No. 4037 Seq. ID No. 4038 1996 Seq. ID No. 4193 Seq. ID No. 4194 2021 Seq. ID No. 4239 Seq. ID No. 4240 2065a Seq. ID No. 4327 Seq. ID No. 4328 2065b Seq. ID No. 4329 Seq. ID No. 4330 2068 Seq. ID No. 4333 Seq. ID No. 4334 2097 Seq. ID No. 4393 Seq. ID No. 4394 2138a Seq. ID No. 4463 Seq. ID No. 4464 2138b Seq. ID No. 4465 Seq. ID No. 4466 2138c Seq. ID No. 4467 Seq. ID No. 4468 2196 Seq. ID No. 4597 Seq. ID No. 4598 2215a Seq. ID No. 4629 Seq. ID No. 4630 2215b Seq. ID No. 4631 Seq. ID No. 4632 2234a Seq. ID No. 4675 Seq. ID No. 4676 2234b Seq. ID No. 4677 Seq. ID No. 4678 2234c Seq. ID No. 4679 Seq. ID No. 4680 2240a Seq. ID No. 4689 Seq. ID No. 4690 2240b Seq. ID No. 4691 Seq. ID No. 4692 2240c Seq. ID No. 4693 Seq. ID No. 4694 2284 Seq. ID No. 4781 Seq. ID No. 4782 2292a Seq. ID No. 4799 Seq. ID No. 4800 2292b Seq. ID No. 4801 Seq. ID No. 4802 2292c Seq. ID No. 4803 Seq. ID No. 4804 2322 Seq. ID No. 4861 Seq. ID No. 4862 2401 Seq. ID No. 5009 Seq. ID No. 5010 2461a Seq. ID No. 5143 Seq. ID No. 5144 2461b Seq. ID No. 5145 Seq. ID No. 5146 2475a Seq. ID No. 5179 Seq. ID No. 5180 2475b Seq. ID No. 5181 Seq. ID No. 5182 2475c Seq. ID No. 5183 Seq. ID No. 5184 2513a Seq. ID No. 5249 Seq. ID No. 5250 2513b Seq. ID No. 5251 Seq. ID No. 5252 2513c Seq. ID No. 5253 Seq. ID No. 5254 2516a Seq. ID No. 5259 Seq. ID No. 5260 2516b Seq. ID No. 5261 Seq. ID No. 5262 2528a Seq. ID No. 5293 Seq. ID No. 5294 2528b Seq. ID No. 5295 Seq. ID No. 5296 2528c Seq. ID No. 5297 Seq. ID No. 5298 2528d Seq. ID No. 5299 Seq. ID No. 5300 2535a Seq. ID No. 5307 Seq. ID No. 5308 2535b Seq. ID No. 5309 Seq. ID No. 5310 2585 Seq. ID No. 5411 Seq. ID No. 5412 2643a Seq. ID No. 5535 Seq. ID No. 5536 2643b Seq. ID No. 5537 Seq. ID No. 5538 2744 Seq. ID No. 5745 Seq. ID No. 5746 2768a Seq. ID No. 5821 Seq. ID No. 5822 2768b Seq. ID No. 5823 Seq. ID No. 5824 2768c Seq. ID No. 5825 Seq. ID No. 5826 2871 Seq. ID No. 6029 Seq. ID No. 6030 2934 Seq. ID No. 6171 Seq. ID No. 6172 2988a Seq. ID No. 6307 Seq. ID No. 6308 2988b Seq. ID No. 6309 Seq. ID No. 6310 2988c Seq. ID No. 6311 Seq. ID No. 6312

Listed in Table 14 are the 39 ORFs whose BlastP results predict for possible capsule biosynthesis and transport. Keywords used in the search are: polysaccharide, saccharide, rhamnos, dexB, aliA, cap[A-Z], cps[A-Z], wze[A-Z], wzh[A-Z], teichu, tuaG, manB, pyrophosphorylase, glucose, eps[ABE], glucosyl, xylos, encapsula, pgs[ABC], exopolysacch, galactos, epimerase, lytR, lytABC, lysR, Transferase, GalNAc, GlcNAc, Spore, LPS, Peptidoglycan, Glutamate, Mannos, Oligosaccharide, Outer core, Arabinose, Teichoic, Teicho, Lipoteichoic, Glycerol, spo[A-Z], capsule, capsular. TABLE 14 CAPSULE RELATED PROTEINS ORF DNA SEQ ID Protein SEQ ID Blast ‘e’ Number Number Number Keyword Description Value  39a Seq. ID No. 49 Seq. ID No. 50 capC capsule biosynthesis 6.00E−19 protein CapC, (pXO2- 57), Baci . . .  39b Seq. ID No. 51 Seq. ID No. 52 capC capsule biosynthesis 7.00E−19 protein CapC, (pXO2- 57), Baci . . .  40 Seq. ID No. 53 Seq. ID No. 54 capB CapB, Bacillus subtilis 9.00E−95 Bacteria; Firmicutes; Baci . . .  41c Seq. ID No. 59 Seq. ID No. 60 capA PgsA, Bacillus subtilis 9.00E−95 Bacteria; Firmicutes; Baci . . .  102 Seq. ID No. 195 Seq. ID No. 196 saccharide Bacillus cereus 1.00E−168 Bacteria; Firmicutes; Bacillus/Clo . . .  330c Seq. ID No. 689 Seq. ID No. 690 transferase Glycosyltransferase, 5.00E−79 Clostridium acetobutylicum Ba . . .  337 Seq. ID No. 703 Seq. ID No. 704 transferase glycosyltransferase, 2.00E−58 Lactococcus lactis subsp. lac . . .  427c Seq. ID No. 925 Seq. ID No. 926 capsular unknown, 2.00E−46 Staphylococcus aureus Bacteria; Firmicute . . .  760 Seq. ID No. Seq. ID No. 1598 dexB maturase-related 6.00E−78 1597 protein, Streptococcus pneumoniae . . .  762b Seq. ID No. Seq. ID No. 1602 cpsL transposase, 1.00E−46 1601 Streptococcus pneumoniae Bacteria; Fi . . .  763b Seq. ID No. Seq. ID No. 1608 capsular transposase, 5.00E−44 1607 Staphylococcus aureus Bacteria; Firmi . . .  766 Seq. ID No. Seq. ID No. 1612 cpsL transposase, 6.00E−44 1611 Streptococcus pneumoniae Bacteria; Fi . . .  767 Seq. ID No. Seq. ID No. 1614 capsular transposase, 4.00E−16 1613 Staphylococcus aureus Bacteria; Firmi . . .  830 Seq. ID No. Seq. ID No. 1714 cpsA Thermostable 4.00E−14 1713 carboxypeptidase (cpsA-2), Sulfolobus . . . 1004a Seq. ID No. Seq ID No. 2030 EpsE unknown, Lactobacillus 1.00E−168 2029 rhamnosus Bacteria; Firmicu . . . 1135b Seq. ID No. Seq. ID No. 2264 capA Bacillus anthracis 3.00E−25 2263 Bacteria; Firmicutes; Bacillus/ . . . 1138 Seq. ID No. Seq. ID No. 2270 saccharide unknown, 9.00E−60 2269 Staphylococcus aureus Bacteria; Firmicute . . . 1177 Seq. ID No. Seq. ID No. 2374 capsular capsular 9.00E−60 2373 polysaccharide biosynthesi . . . U67548 . . . 1200 Seq. ID No. Seq. ID No. 2438 xylos acetylxylosidase, 9.00E−36 2437 Caldicellulosiruptor saccharolyt . . . 1288 Seq. ID No. Seq. ID No. 2652 lytR membrane bound 3.00E−42 2651 protein, Bacillus subtilis Bacteria . . . 1355 Seq. ID No. Seq. ID No. 2768 manB probable 1.00E−136 2767 phosphomannomutase, Clostridium perfringe . . . 1426b Seq. ID No. Seq. ID No. 2908 polysaccharide Orfde2, Enterococcus 1.00E−103 2907 faecalis Bacteria; Firmicutes . . . 1646e Seq. ID No. Seq. ID No. 3398 polysaccharide putative polysaccharide 3.00E−24 3397 biosynthesis protein, Stre . . . 1646f Seq. ID No. Seq. ID No. 3400 polysaccharide putative polysaccharide 3.00E−78 3399 biosynthesis protein, Stre . . . 1682b Seq. ID No. Seq. ID No. 3480 polysaccharide methionine 2.00E−68 3479 aminopeptidase A, Enterococcus faecalis . . . 1685 Seq. ID No. Seq. ID No. 3488 glucose UDP-glucose 4- 1.00E−111 3487 epimerase, Streptococcus pneumoniae . . . 1688a Seq. ID No. Seq. ID No. 3492 polysaccharide Orfde3, Enterococcus 3.00E−78 3491 faecalis Bacteria; Firmicutes . . . 1688b Seq. ID No. Seq. ID No. 3494 polysaccharide Orfde3, Enterococcus 9.00E−34 3493 faecalis Bacteria; Firmicutes . . . 1688c Seq. ID No. Seq. ID No. 3496 transferase RgpG, Lactobacillus 4.00E−99 3495 delbrueckii Bacteria; Firmicut . . . 1689a Seq. ID No. Seq. ID No. 3498 tuaG teichuronic acid 9.00E−53 3497 biosynthesis, Bacillus halodurans . . . 1094d Seq. ID No. Seq. ID No. 3520 lytR attenuator for lytABC 6.00E−69 3519 and lytR expression, Bacillu . . . 1696 Seq. ID No. Seq. ID No. 3522 glucose putative UDP-glucose 1.00E−157 3521 dehydrogenase, Escherichia co . . . 1699b Seq. ID No. Seq. ID No. 3530 teichu unknown, Bacillus 8.00E−30 3529 subtilis Bacteria; Firmicutes; G . . . 1701a Seq. ID No. Seq. ID No. 3536 mannos alpha-D-mannose- 1.00E−84 3535 alpha(1-6)phospha . . . AP001516 . . . 1710b Seq. ID No. Seq. ID No. 3562 LPS LPS biosynthesis 4.00E−12 3561 protein RfaE, Ps . . . AE004912 . . . 1855 Seq. ID No. Seq. ID No. 3884 capsule Regulatory function on 5.00E−38 3883 capsule ex . . . AE008458 . . . 1857c Seq. ID No. Seq. ID No. 3892 polysaccharide Staphylococcus aureus 1.00E−13 3891 subsp. aureus N315 Bacteria; . . . 1902a Seq. ID No. Seq. ID No. 3982 capsular DNA topoisomerase IV 7.00E−15 3981 subunit B, Streptococcus agal . . . 1951d Seq. ID No. Seq. ID No. 4088 saccharide Phospholipid- 7.00E−84 4087 lipopolysaccharide A . . . AE010571 . . .

Three potential capsule loci have been identified based on BlastP analysis listed in Table 14: poly-gamma-glutamate from base 20186 to 24645, sugar transport from base 159934 to 172757, and teichuronic from base 886658 to 930066. Table 15 lists the ORFs found within these regions. TABLE 15 CAPSULE LOCI ORF DNA SEQ ID Protein SEQ Number Number ID Number Locus 38a Seq. ID No. 45 Seq. ID No. 46 Poly-gamma-glutamate 38b Seq. ID No. 47 Seq. ID No. 48 Poly-gamma-glutamate 39b Seq. ID No. 51 Seq. ID No. 52 Poly-gamma-glutamate 40 Seq. ID No. 53 Seq. ID No. 54 Poly-gamma-glutamate 41a Seq. ID No. 55 Seq. ID No. 56 Poly-gamma-glutamate 41b Seq. ID No. 57 Seq. ID No. 58 Poly-gamma-glutamate 41c Seq. ID No. 59 Seq. ID No. 60 Poly-gamma-glutamate 329 Seq. ID No. 683 Seq. ID No. 684 sugar transport 330a Seq. ID No. 685 Seq. ID No. 686 sugar transport 330b Seq. ID No. 687 Seq. ID No. 688 sugar transport 330c Seq. ID No. 689 Seq. ID No. 690 sugar transport 331 Seq. ID No. 691 Seq. ID No. 670 sugar transport 332 Seq. ID No. 693 Seq. ID No. 694 sugar transport 333 Seq. ID No. 695 Seq. ID No. 696 sugar transport 334 Seq. ID No. 687 Seq. ID No. 698 sugar transport 335a Seq. ID No. 699 Seq. ID No. 670 sugar transport 335b Seq. ID No. 701 Seq. ID No. 702 sugar transport 337 Seq. ID No. 703 Seq. ID No. 704 sugar transport 338a Seq. ID No. 705 Seq. ID No. 706 sugar transport 338b Seq. ID No. 707 Seq. ID No. 708 sugar transport 338c Seq. ID No. 709 Seq. ID No. 710 sugar transport 341a Seq. ID No. 711 Seq. ID No. 712 sugar transport 341b Seq. ID No. 713 Seq. ID No. 714 sugar transport 342a Seq. ID No. 715 Seq. ID No. 716 sugar transport 342b Seq. ID No. 717 Seq. ID No. 718 sugar transport 342c Seq. ID No. 719 Seq. ID No. 720 sugar transport 342d Seq. ID No. 721 Seq. ID No. 722 sugar transport 342e Seq. ID No. 723 Seq. ID No. 724 sugar transport 342f Seq. ID No. 725 Seq. ID No. 726 sugar transport 342g Seq. ID No. 727 Seq. ID No. 728 sugar transport 342h Seq. ID No. 729 Seq. ID No. 730 sugar transport 344a Seq. ID No. 731 Seq. ID No. 732 sugar transport 344b Seq. ID No. 733 Seq. ID No. 734 sugar transport 345 Seq. ID No. 735 Seq. ID No. 736 sugar transport 346a Seq. ID No. 737 Seq. ID No. 738 sugar transport 346b Seq. ID No. 739 Seq. ID No. 740 sugar transport 347 Seq. ID No. 741 Seq. ID No. 742 sugar transport 349a Seq. ID No. 743 Seq. ID No. 744 sugar transport 349b Seq. ID No. 745 Seq. ID No. 746 sugar transport 349c Seq. ID No. 747 Seq. ID No. 748 sugar transport 350a Seq. ID No. 749 Seq. ID No. 750 sugar transport 350b Seq. ID No. 751 Seq. ID No. 752 sugar transport 351 Seq. ID No. 753 Seq. ID No. 754 sugar transport 1646a Seq. ID No. 3389 Seq. ID No. 3390 Teichuronic 1646b Seq. ID No. 3391 Seq. ID No. 3392 Teichuronic 1646c Seq. ID No. 3393 Seq. ID No. 3394 Teichuronic 1646d Seq. ID No. 3395 Seq. ID No. 3396 Teichuronic 1646e Seq. ID No. 3397 Seq. ID No. 3398 Teichuronic 1646f Seq. ID No. 3399 Seq. ID No. 3400 Teichuronic 1647 Seq. ID No. 3401 Seq. ID No. 3402 Teichuronic 1648b Seq. ID No. 3403 Seq. ID No. 3404 Teichuronic 1649a Seq. ID No. 3405 Seq. ID No. 3406 Teichuronic 1649b Seq. ID No. 3407 Seq. ID No. 3408 Teichuronic 1649c Seq. ID No. 3409 Seq. ID No. 3410 Teichuronic 1652a Seq. ID No. 3411 Seq. ID No. 3412 Teichuronic 1652b Seq. ID No. 3413 Seq. ID No. 3414 Teichuronic 1654 Seq. ID No. 3415 Seq. ID No. 3416 Teichuronic 1656b Seq. ID No. 3417 Seq. ID No. 3418 Teichuronic 1657 Seq. ID No. 3419 Seq. ID No. 3420 Teichuronic 1659a Seq. ID No. 3421 Seq. ID No. 3422 Teichuronic 1659b Seq. ID No. 3423 Seq. ID No. 3424 Teichuronic 1659c Seq. ID No. 3425 Seq. ID No. 3426 Teichuronic 1660b Seq. ID No. 3427 Seq. ID No. 3428 Teichuronic 1662a Seq. ID No. 3429 Seq. ID No. 3430 Teichuronic 1662b Seq. ID No. 3431 Seq. ID No. 3432 Teichuronic 1663 Seq. ID No. 3433 Seq. ID No. 3434 Teichuronic 1664 Seq. ID No. 3435 Seq. ID No. 3436 Teichuronic 1665a Seq. ID No. 3437 Seq. ID No. 3438 Teichuronic 1668 Seq. ID No. 3439 Seq. ID No. 3440 Teichuronic 1669 Seq. ID No. 3441 Seq. ID No. 3442 Teichuronic 1670a Seq. ID No. 3443 Seq. ID No. 3444 Teichuronic 1670b Seq. ID No. 3445 Seq. ID No. 3446 Teichuronic 1670c Seq. ID No. 3447 Seq. ID No. 3448 Teichuronic 1673a Seq. ID No. 3449 Seq. ID No. 3450 Teichuronic 1673b Seq. ID No. 3451 Seq. ID No. 3452 Teichuronic 1673c Seq. ID No. 3453 Seq. ID No. 3454 Teichuronic 1673d Seq. ID No. 3455 Seq. ID No. 3456 Teichuronic 1673e Seq. ID No. 3457 Seq. ID No. 3458 Teichuronic 1673f Seq. ID No. 3459 Seq. ID No. 3460 Teichuronic 1674 Seq. ID No. 3461 Seq. ID No. 3462 Teichuronic 1675a Seq. ID No. 3463 Seq. ID No. 3464 Teichuronic 1675b Seq. ID No. 3465 Seq. ID No. 3466 Teichuronic 1675c Seq. ID No. 3467 Seq. ID No. 3468 Teichuronic 1676 Seq. ID No. 3469 Seq. ID No. 3470 Teichuronic 1677 Seq. ID No. 3471 Seq. ID No. 3472 Teichuronic 1679 Seq. ID No. 3473 Seq. ID No. 3474 Teichuronic 1680 Seq. ID No. 3475 Seq. ID No. 3476 Teichuronic 1682a Seq. ID No. 3477 Seq. ID No. 3478 Teichuronic 1682b Seq. ID No. 3479 Seq. ID No. 3480 Teichuronic 1683a Seq. ID No. 3481 Seq. ID No. 3482 Teichuronic 1683b Seq. ID No. 3483 Seq. ID No. 3484 Teichuronic 1684 Seq. ID No. 3485 Seq. ID No. 3486 Teichuronic 1685 Seq. ID No. 3487 Seq. ID No. 3488 Teichuronic 1687 Seq. ID No. 3489 Seq. ID No. 3490 Teichuronic 1688a Seq. ID No. 3491 Seq. ID No. 3492 Teichuronic 1688b Seq. ID No. 3493 Seq. ID No. 3494 Teichuronic 1688c Seq. ID No. 3495 Seq. ID No. 3496 Teichuronic 1689a Seq. ID No. 3497 Seq. ID No. 3498 Teichuronic 1689b Seq. ID No. 3499 Seq. ID No. 3500 Teichuronic 1689c Seq. ID No. 3501 Seq. ID No. 3502 Teichuronic 1690a Seq. ID No. 3503 Seq. ID No. 3504 Teichuronic 1690b Seq. ID No. 3505 Seq. ID No. 3506 Teichuronic 1691 Seq. ID No. 3507 Seq. ID No. 3508 Teichuronic 1692 Seq. ID No. 3509 Seq. ID No. 3510 Teichuronic 1693 Seq. ID No. 3511 Seq. ID No. 3512 Teichuronic 1694a Seq. ID No. 3513 Seq. ID No. 3514 Teichuronic 1694b Seq. ID No. 3515 Seq. ID No. 3516 Teichuronic 1694c Seq. ID No. 3517 Seq. ID No. 3518 Teichuronic 1694d Seq. ID No. 3519 Seq. ID No. 3520 Teichuronic 1696 Seq. ID No. 3521 Seq. ID No. 3522 Teichuronic 1697a Seq. ID No. 3523 Seq. ID No. 3524 Teichuronic 1697b Seq. ID No. 3525 Seq. ID No. 3526 Teichuronic 1699a Seq. ID No. 3527 Seq. ID No. 3528 Teichuronic 1699b Seq. ID No. 3529 Seq. ID No. 3530 Teichuronic 1700a Seq. ID No. 3531 Seq. ID No. 3532 Teichuronic 1700b Seq. ID No. 3533 Seq. ID No. 3534 Teichuronic 1701a Seq. ID No. 3535 Seq. ID No. 3536 Teichuronic 1701b Seq. ID No. 3537 Seq. ID No. 3538 Teichuronic 1703b Seq. ID No. 3539 Seq. ID No. 3540 Teichuronic 1704a Seq. ID No. 3541 Seq. ID No. 3542 Teichuronic 1704b Seq. ID No. 3543 Seq. ID No. 3544 Teichuronic 1705a Seq. ID No. 3545 Seq. ID No. 3546 Teichuronic 1705b Seq. ID No. 3547 Seq. ID No. 3548 Teichuronic 1706 Seq. ID No. 3549 Seq. ID No. 3550 Teichuronic 1707a Seq. ID No. 3551 Seq. ID No. 3552 Teichuronic 1707b Seq. ID No. 3553 Seq. ID No. 3554 Teichuronic 1708 Seq. ID No. 3555 Seq. ID No. 3556 Teichuronic 1709 Seq. ID No. 3557 Seq. ID No. 3558 Teichuronic 1710a Seq. ID No. 3559 Seq. ID No. 3560 Teichuronic 1710b Seq. ID No. 3561 Seq. ID No. 3562 Teichuronic

Listed in Table 16 are 14 ORFs determined by keyword search of the BlastP associated with sporulation. TABLE 16 SPORULATION RELATED PROTEINS ORF Number DNA SEQ ID Number Protein SEQ ID Number 524b Seq. ID No. 1137 Seq. ID No. 1138 683b Seq. ID No. 1455 Seq. ID No. 1456 1058 Seq. ID No. 2137 Seq. ID No. 2138 1060b Seq. ID No. 2141 Seq. ID No. 2142 1070b Seq. ID No. 2165 Seq. ID No. 2166 1077e Seq. ID No. 2179 Seq. ID No. 2180 1149 Seq. ID No. 2301 Seq. ID No. 2302 1348 Seq. ID No. 2753 Seq. ID No. 2754 2011c Seq. ID No. 4211 Seq. ID No. 4212 2024d Seq. ID No. 4251 Seq. ID No. 4252 2065a Seq. ID No. 4327 Seq. ID No. 4328 2181a Seq. ID No. 4569 Seq. ID No. 4570 2256 Seq. ID No. 4719 Seq. ID No. 4720 2260c Seq. ID No. 4729 Seq. ID No. 4730

Listed in Table 17 are the 913 start to stop ORFs which are unique to Alloiococcus otitidis, or 653 unique Stop-Stop ORFs identified as having a BlastP ‘E Value’ of >e⁻¹⁰ (not identified separately in Table 17). TABLE 17 UNIQUE ORFs ORF Number DNA SEQ ID Number Protein SEQ ID Number 4a Seq. ID No. 7 Seq. ID No. 8 11 Seq. ID No. 19 Seq. ID No. 20 13a Seq. ID No. 21 Seq. ID No. 22 16 Seq. ID No. 23 Seq. ID No. 24 21b Seq. ID No. 31 Seq. ID No. 32 32 Seq. ID No. 39 Seq. ID No. 40 44a Seq. ID No. 65 Seq. ID No. 66 44b Seq. ID No. 67 Seq. ID No. 68 45 Seq. ID No. 69 Seq. ID No. 70 55 Seq. ID No. 91 Seq. ID No. 92 58 Seq. ID No. 99 Seq. ID No. 100 61 Seq. ID No. 105 Seq. ID No. 106 63a Seq. ID No. 113 Seq. ID No. 114 63b Seq. ID No. 115 Seq. ID No. 116 66a Seq. ID No. 123 Seq. ID No. 124 67 Seq. ID No. 125 Seq. ID No. 126 69 Seq. ID No. 127 Seq. ID No. 128 73a Seq. ID No. 131 Seq. ID No. 132 73b Seq. ID No. 133 Seq. ID No. 134 79 Seq. ID No. 139 Seq. ID No. 140 83 Seq. ID No. 151 Seq. ID No. 152 86 Seq. ID No. 159 Seq. ID No. 160 87a Seq. ID No. 161 Seq. ID No. 162 87b Seq. ID No. 163 Seq. ID No. 164 87c Seq. ID No. 165 Seq. ID No. 166 89 Seq. ID No. 169 Seq. ID No. 170 94 Seq. ID No. 185 Seq. ID No. 186 97b Seq. ID No. 189 Seq. ID No. 190 101 Seq. ID No. 193 Seq. ID No. 194 119a Seq. ID No. 229 Seq. ID No. 230 119b Seq. ID No. 231 Seq. ID No. 232 132a Seq. ID No. 255 Seq. ID No. 256 132b Seq. ID No. 257 Seq. ID No. 258 132c Seq. ID No. 259 Seq. ID No. 260 142 Seq. ID No. 275 Seq. ID No. 276 163 Seq. ID No. 337 Seq. ID No. 338 164 Seq. ID No. 339 Seq. ID No. 340 169 Seq. ID No. 347 Seq. ID No. 348 170 Seq. ID No. 349 Seq. ID No. 350 173 Seq. ID No. 357 Seq. ID No. 358 174 Seq. ID No. 359 Seq. ID No. 360 179a Seq. ID No. 369 Seq. ID No. 370 179b Seq. ID No. 371 Seq. ID No. 372 183a Seq. ID No. 377 Seq. ID No. 378 187a Seq. ID No. 385 Seq. ID No. 386 187b Seq. ID No. 387 Seq. ID No. 388 191b Seq. ID No. 393 Seq. ID No. 394 193 Seq. ID No. 399 Seq. ID No. 400 194a Seq. ID No. 401 Seq. ID No. 402 194b Seq. ID No. 403 Seq. ID No. 404 196 Seq. ID No. 407 Seq. ID No. 408 201a Seq. ID No. 419 Seq. ID No. 420 207 Seq. ID No. 431 Seq. ID No. 432 235a Seq. ID No. 477 Seq. ID No. 478 241 Seq. ID No. 495 Seq. ID No. 496 247 Seq. ID No. 507 Seq. ID No. 508 253a Seq. ID No. 519 Seq. ID No. 520 260 Seq. ID No. 541 Seq. ID No. 542 263a Seq. ID No. 545 Seq. ID No. 546 263b Seq. ID No. 547 Seq. ID No. 548 264b Seq. ID No. 549 Seq. ID No. 550 268 Seq. ID No. 557 Seq. ID No. 558 282 Seq. ID No. 589 Seq. ID No. 590 297 Seq. ID No. 617 Seq. ID No. 618 300b Seq. ID No. 619 Seq. ID No. 620 309 Seq. ID No. 633 Seq. ID No. 634 313a Seq. ID No. 639 Seq. ID No. 640 313b Seq. ID No. 641 Seq. ID No. 642 313c Seq. ID No. 643 Seq. ID No. 644 313d Seq. ID No. 645 Seq. ID No. 646 313e Seq. ID No. 647 Seq. ID No. 648 316a Seq. ID No. 651 Seq. ID No. 652 317a Seq. ID No. 653 Seq. ID No. 654 317b Seq. ID No. 655 Seq. ID No. 656 320 Seq. ID No. 667 Seq. ID No. 668 331 Seq. ID No. 691 Seq. ID No. 692 332 Seq. ID No. 693 Seq. ID No. 694 333 Seq. ID No. 695 Seq. ID No. 696 334 Seq. ID No. 697 Seq. ID No. 698 342a Seq. ID No. 715 Seq. ID No. 716 342b Seq. ID No. 717 Seq. ID No. 718 342c Seq. ID No. 719 Seq. ID No. 720 344a Seq. ID No. 731 Seq. ID No. 732 344b Seq. ID No. 733 Seq. ID No. 734 347 Seq. ID No. 741 Seq. ID No. 742 349a Seq. ID No. 743 Seq. ID No. 744 349b Seq. ID No. 745 Seq. ID No. 746 349c Seq. ID No. 747 Seq. ID No. 748 350a Seq. ID No. 749 Seq. ID No. 750 350b Seq. ID No. 751 Seq. ID No. 752 352a Seq. ID No. 755 Seq. ID No. 756 352b Seq. ID No. 757 Seq. ID No. 758 352c Seq. ID No. 759 Seq. ID No. 760 354a Seq. ID No. 761 Seq. ID No. 762 354b Seq. ID No. 763 Seq. ID No. 764 354c Seq. ID No. 765 Seq. ID No. 766 355 Seq. ID No. 767 Seq. ID No. 768 372a Seq. ID No. 801 Seq. ID No. 802 372b Seq. ID No. 803 Seq. ID No. 804 372c Seq. ID No. 805 Seq. ID No. 806 372d Seq. ID No. 807 Seq. ID No. 808 374 Seq. ID No. 809 Seq. ID No. 810 377a Seq. ID No. 811 Seq. ID No. 812 377b Seq. ID No. 813 Seq. ID No. 814 386 Seq. ID No. 833 Seq. ID No. 834 393b Seq. ID No. 841 Seq. ID No. 842 396 Seq. ID No. 849 Seq. ID No. 850 398 Seq. ID No. 851 Seq. ID No. 852 400a Seq. ID No. 853 Seq. ID No. 854 400b Seq. ID No. 855 Seq. ID No. 856 416a Seq. ID No. 887 Seq. ID No. 888 416b Seq. ID No. 889 Seq. ID No. 890 417 Seq. ID No. 891 Seq. ID No. 892 420a Seq. ID No. 903 Seq. ID No. 904 420b Seq. ID No. 905 Seq. ID No. 906 422 Seq. ID No. 909 Seq. ID No. 910 434 Seq. ID No. 937 Seq. ID No. 938 437b Seq. ID No. 941 Seq. ID No. 942 437c Seq. ID No. 943 Seq. ID No. 944 440 Seq. ID No. 951 Seq. ID No. 952 443b Seq. ID No. 957 Seq. ID No. 958 451a Seq. ID No. 973 Seq. ID No. 974 451b Seq. ID No. 975 Seq. ID No. 976 454b Seq. ID No. 987 Seq. ID No. 988 462 Seq. ID No. 1005 Seq. ID No. 1006 463a Seq. ID No. 1007 Seq. ID No. 1008 463b Seq. ID No. 1009 Seq. ID No. 1010 464a Seq. ID No. 1011 Seq. ID No. 1012 465b Seq. ID No. 1019 Seq. ID No. 1020 471a Seq. ID No. 1025 Seq. ID No. 1026 471b Seq. ID No. 1027 Seq. ID No. 1028 476 Seq. ID No. 1045 Seq. ID No. 1046 477b Seq. ID No. 1047 Seq. ID No. 1048 491a Seq. ID No. 1071 Seq. ID No. 1072 491b Seq. ID No. 1073 Seq. ID No. 1074 494a Seq. ID No. 1077 Seq. ID No. 1078 507a Seq. ID No. 1105 Seq. ID No. 1106 507b Seq. ID No. 1107 Seq. ID No. 1108 510 Seq. ID No. 1111 Seq. ID No. 1112 521b Seq. ID No. 1131 Seq. ID No. 1132 524a Seq. ID No. 1135 Seq. ID No. 1136 525 Seq. ID No. 1139 Seq. ID No. 1140 530a Seq. ID No. 1151 Seq. ID No. 1152 530b Seq. ID No. 1153 Seq. ID No. 1154 541a Seq. ID No. 1165 Seq. ID No. 1166 541b Seq. ID No. 1167 Seq. ID No. 1168 541c Seq. ID No. 1169 Seq. ID No. 1170 541d Seq. ID No. 1171 Seq. ID No. 1172 542 Seq. ID No. 1173 Seq. ID No. 1174 544 Seq. ID No. 1181 Seq. ID No. 1182 545a Seq. ID No. 1183 Seq. ID No. 1184 545b Seq. ID No. 1185 Seq. ID No. 1186 545c Seq. ID No. 1187 Seq. ID No. 1188 546a Seq. ID No. 1189 Seq. ID No. 1190 546b Seq. ID No. 1191 Seq. ID No. 1192 546c Seq. ID No. 1193 Seq. ID No. 1194 547a Seq. ID No. 1195 Seq. ID No. 1196 547b Seq. ID No. 1197 Seq. ID No. 1198 548 Seq. ID No. 1199 Seq. ID No. 1200 549b Seq. ID No. 1201 Seq. ID No. 1202 550a Seq. ID No. 1203 Seq. ID No. 1204 553c Seq. ID No. 1207 Seq. ID No. 1208 556 Seq. ID No. 1213 Seq. ID No. 1214 564a Seq. ID No. 1227 Seq. ID No. 1228 564b Seq. ID No. 1229 Seq. ID No. 1230 571 Seq. ID No. 1239 Seq. ID No. 1240 576a Seq. ID No. 1243 Seq. ID No. 1244 576b Seq. ID No. 1245 Seq. ID No. 1246 578a Seq. ID No. 1247 Seq. ID No. 1248 578b Seq. ID No. 1249 Seq. ID No. 1250 585b Seq. ID No. 1259 Seq. ID No. 1260 587a Seq. ID No. 1265 Seq. ID No. 1266 587b Seq. ID No. 1267 Seq. ID No. 1268 587c Seq. ID No. 1269 Seq. ID No. 1270 587d Seq. ID No. 1271 Seq. ID No. 1272 588a Seq. ID No. 1273 Seq. ID No. 1274 588b Seq. ID No. 1275 Seq. ID No. 1276 589a Seq. ID No. 1277 Seq. ID No. 1278 589b Seq. ID No. 1279 Seq. ID No. 1280 590 Seq. ID No. 1281 Seq. ID No. 1282 595a Seq. ID No. 1283 Seq. ID No. 1284 595b Seq. ID No. 1285 Seq. ID No. 1286 596a Seq. ID No. 1287 Seq. ID No. 1288 596b Seq. ID No. 1289 Seq. ID No. 1290 596c Seq. ID No. 1291 Seq. ID No. 1292 597 Seq. ID No. 1293 Seq. ID No. 1294 598a Seq. ID No. 1295 Seq. ID No. 1296 598b Seq. ID No. 1297 Seq. ID No. 1298 599a Seq. ID No. 1299 Seq. ID No. 1300 599b Seq. ID No. 1301 Seq. ID No. 1302 600a Seq. ID No. 1303 Seq. ID No. 1304 600b Seq. ID No. 1305 Seq. ID No. 1306 603a Seq. ID No. 1307 Seq. ID No. 1308 606 Seq. ID No. 1309 Seq. ID No. 1310 607a Seq. ID No. 1311 Seq. ID No. 1312 607b Seq. ID No. 1313 Seq. ID No. 1314 610a Seq. ID No. 1319 Seq. ID No. 1320 610b Seq. ID No. 1321 Seq. ID No. 1322 611 Seq. ID No. 1323 Seq. ID No. 1324 613a Seq. ID No. 1325 Seq. ID No. 1326 613b Seq. ID No. 1327 Seq. ID No. 1328 615b Seq. ID No. 1337 Seq. ID No. 1338 619a Seq. ID No. 1341 Seq. ID No. 1342 619b Seq. ID No. 1343 Seq. ID No. 1344 623 Seq. ID No. 1347 Seq. ID No. 1348 624a Seq. ID No. 1349 Seq. ID No. 1350 624b Seq. ID No. 1351 Seq. ID No. 1352 624c Seq. ID No. 1353 Seq. ID No. 1354 625 Seq. ID No. 1355 Seq. ID No. 1356 632b Seq. ID No. 1371 Seq. ID No. 1372 634b Seq. ID No. 1379 Seq. ID No. 1380 636 Seq. ID No. 1381 Seq. ID No. 1382 640 Seq. ID No. 1389 Seq. ID No. 1390 644a Seq. ID No. 1397 Seq. ID No. 1398 644b Seq. ID No. 1399 Seq. ID No. 1400 645 Seq. ID No. 1401 Seq. ID No. 1402 658a Seq. ID No. 1417 Seq. ID No. 1418 658b Seq. ID No. 1419 Seq. ID No. 1420 659a Seq. ID No. 1421 Seq. ID No. 1422 659b Seq. ID No. 1423 Seq. ID No. 1424 676 Seq. ID No. 1439 Seq. ID No. 1440 679a Seq. ID No. 1445 Seq. ID No. 1446 679b Seq. ID No. 1447 Seq. ID No. 1448 684 Seq. ID No. 1457 Seq. ID No. 1458 690 Seq. ID No. 1465 Seq. ID No. 1466 699b Seq. ID No. 1479 Seq. ID No. 1480 721 Seq. ID No. 1511 Seq. ID No. 1512 739 Seq. ID No. 1551 Seq. ID No. 1552 740 Seq. ID No. 1553 Seq. ID No. 1554 741a Seq. ID No. 1555 Seq. ID No. 1556 741b Seq. ID No. 1557 Seq. ID No. 1558 749 Seq. ID No. 1579 Seq. ID No. 1580 764 Seq. ID No. 1609 Seq. ID No. 1610 772a Seq. ID No. 1621 Seq. ID No. 1622 772b Seq. ID No. 1623 Seq. ID No. 1624 774 Seq. ID No. 1625 Seq. ID No. 1626 775 Seq. ID No. 1627 Seq. ID No. 1628 777a Seq. ID No. 1629 Seq. ID No. 1630 777c Seq. ID No. 1631 Seq. ID No. 1632 779 Seq. ID No. 1633 Seq. ID No. 1634 782b Seq. ID No. 1639 Seq. ID No. 1640 786b Seq. ID No. 1643 Seq. ID No. 1644 791 Seq. ID No. 1655 Seq. ID No. 1656 795 Seq. ID No. 1667 Seq. ID No. 1668 799a Seq. ID No. 1671 Seq. ID No. 1672 808 Seq. ID No. 1693 Seq. ID No. 1694 809b Seq. ID No. 1695 Seq. ID No. 1696 816 Seq. ID No. 1701 Seq. ID No. 1702 820a Seq. ID No. 1703 Seq. ID No. 1704 820b Seq. ID No. 1705 Seq. ID No. 1706 835a Seq. ID No. 1721 Seq. ID No. 1722 835b Seq. ID No. 1723 Seq. ID No. 1724 837a Seq. ID No. 1731 Seq. ID No. 1732 843 Seq. ID No. 1737 Seq. ID No. 1738 848 Seq. ID No. 1743 Seq. ID No. 1744 854 Seq. ID No. 1759 Seq. ID No. 1760 857 Seq. ID No. 1763 Seq. ID No. 1764 860 Seq. ID No. 1773 Seq. ID No. 1774 862 Seq. ID No. 1775 Seq. ID No. 1776 863 Seq. ID No. 1777 Seq. ID No. 1778 864a Seq. ID No. 1779 Seq. ID No. 1780 864b Seq. ID No. 1781 Seq. ID No. 1782 874a Seq. ID No. 1799 Seq. ID No. 1800 874b Seq. ID No. 1801 Seq. ID No. 1802 875 Seq. ID No. 1803 Seq. ID No. 1804 878a Seq. ID No. 1807 Seq. ID No. 1808 887 Seq. ID No. 1823 Seq. ID No. 1824 894 Seq. ID No. 1831 Seq. ID No. 1832 917 Seq. ID No. 1851 Seq. ID No. 1852 919 Seq. ID No. 1857 Seq. ID No. 1858 931 Seq. ID No. 1875 Seq. ID No. 1876 943 Seq. ID No. 1899 Seq. ID No. 1900 950 Seq. ID No. 1915 Seq. ID No. 1916 955a Seq. ID No. 1927 Seq. ID No. 1928 955b Seq. ID No. 1929 Seq. ID No. 1930 978a Seq. ID No. 1973 Seq. ID No. 1974 979 Seq. ID No. 1977 Seq. ID No. 1978 981a Seq. ID No. 1981 Seq. ID No. 1982 993 Seq. ID No. 2005 Seq. ID No. 2006 994 Seq. ID No. 2007 Seq. ID No. 2008 995 Seq. ID No. 2009 Seq. ID No. 2010 997 Seq. ID No. 2011 Seq. ID No. 2012 999a Seq. ID No. 2017 Seq. ID No. 2018 999b Seq. ID No. 2019 Seq. ID No. 2020 1001 Seq. ID No. 2023 Seq. ID No. 2024 1003a Seq. ID No. 2025 Seq. ID No. 2026 1003b Seq. ID No. 2027 Seq. ID No. 2028 1012 Seq. ID No. 2039 Seq. ID No. 2040 1013a Seq. ID No. 2041 Seq. ID No. 2042 1013b Seq. ID No. 2043 Seq. ID No. 2044 1013c Seq. ID No. 2045 Seq. ID No. 2046 1017a Seq. ID No. 2049 Seq. ID No. 2050 1035a Seq. ID No. 2081 Seq. ID No. 2082 1035b Seq. ID No. 2083 Seq. ID No. 2084 1035c Seq. ID No. 2085 Seq. ID No. 2086 1044a Seq. ID No. 2105 Seq. ID No. 2106 1044b Seq. ID No. 2107 Seq. ID No. 2108 1044c Seq. ID No. 2109 Seq. ID No. 2110 1044d Seq. ID No. 2111 Seq. ID No. 2112 1055 Seq. ID No. 2129 Seq. ID No. 2130 1056a Seq. ID No. 2131 Seq. ID No. 2132 1056b Seq. ID No. 2133 Seq. ID No. 2134 1063 Seq. ID No. 2145 Seq. ID No. 2146 1066a Seq. ID No. 2155 Seq. ID No. 2156 1066b Seq. ID No. 2157 Seq. ID No. 2158 1067 Seq. ID No. 2159 Seq. ID No. 2160 1069 Seq. ID No. 2161 Seq. ID No. 2162 1077a Seq. ID No. 2171 Seq. ID No. 2172 1081a Seq. ID No. 2187 Seq. ID No. 2188 1081b Seq. ID No. 2189 Seq. ID No. 2190 1091a Seq. ID No. 2201 Seq. ID No. 2202 1091b Seq. ID No. 2203 Seq. ID No. 2204 1095a Seq. ID No. 2209 Seq. ID No. 2210 1095b Seq. ID No. 2211 Seq. ID No. 2212 1097 Seq. ID No. 2219 Seq. ID No. 2220 1101a Seq. ID No. 2225 Seq. ID No. 2226 1112a Seq. ID No. 2243 Seq. ID No. 2244 1125 Seq. ID No. 2245 Seq. ID No. 2246 1126a Seq. ID No. 2247 Seq. ID No. 2248 1126b Seq. ID No. 2249 Seq. ID No. 2250 1126c Seq. ID No. 2251 Seq. ID No. 2252 1128 Seq. ID No. 2255 Seq. ID No. 2256 1141a Seq. ID No. 2277 Seq. ID No. 2278 1141b Seq. ID No. 2279 Seq. ID No. 2280 1162 Seq. ID No. 2341 Seq. ID No. 2342 1168 Seq. ID No. 2351 Seq. ID No. 2352 1169a Seq. ID No. 2353 Seq. ID No. 2354 1169b Seq. ID No. 2355 Seq. ID No. 2356 1169c Seq. ID No. 2357 Seq. ID No. 2358 1170 Seq. ID No. 2359 Seq. ID No. 2360 1172 Seq. ID No. 2365 Seq. ID No. 2366 1173 Seq. ID No. 2367 Seq. ID No. 2368 1175 Seq. ID No. 2371 Seq. ID No. 2372 1178 Seq. ID No. 2375 Seq. ID No. 2376 1182a Seq. ID No. 2393 Seq. ID No. 2394 1182b Seq. ID No. 2395 Seq. ID No. 2396 1196a Seq. ID No. 2425 Seq. ID No. 2426 1196b Seq. ID No. 2427 Seq. ID No. 2428 1198 Seq. ID No. 2431 Seq. ID No. 2432 1201 Seq. ID No. 2439 Seq. ID No. 2440 1202a Seq. ID No. 2441 Seq. ID No. 2442 1202b Seq. ID No. 2443 Seq. ID No. 2444 1206 Seq. ID No. 2447 Seq. ID No. 2448 1212 Seq. ID No. 2459 Seq. ID No. 2460 1220 Seq. ID No. 2479 Seq. ID No. 2480 1225 Seq. ID No. 2493 Seq. ID No. 2494 1229b Seq. ID No. 2501 Seq. ID No. 2502 1229c Seq. ID No. 2503 Seq. ID No. 2504 1235 Seq. ID No. 2521 Seq. ID No. 2522 1236a Seq. ID No. 2523 Seq. ID No. 2524 1239 Seq. ID No. 2527 Seq. ID No. 2528 1260 Seq. ID No. 2591 Seq. ID No. 2592 1267a Seq. ID No. 2601 Seq. ID No. 2602 1267b Seq. ID No. 2603 Seq. ID No. 2604 1270 Seq. ID No. 2611 Seq. ID No. 2612 1278a Seq. ID No. 2627 Seq. ID No. 2628 1278b Seq. ID No. 2629 Seq. ID No. 2630 1289 Seq. ID No. 2653 Seq. ID No. 2654 1294a Seq. ID No. 2661 Seq. ID No. 2662 1314b Seq. ID No. 2691 Seq. ID No. 2692 1316 Seq. ID No. 2695 Seq. ID No. 2696 1317 Seq. ID No. 2697 Seq. ID No. 2698 1323b Seq. ID No. 2717 Seq. ID No. 2718 1334a Seq. ID No. 2729 Seq. ID No. 2730 1334b Seq. ID No. 2731 Seq. ID No. 2732 1335a Seq. ID No. 2733 Seq. ID No. 2734 1335b Seq. ID No. 2735 Seq. ID No. 2736 1338 Seq. ID No. 2739 Seq. ID No. 2740 1340a Seq. ID No. 2741 Seq. ID No. 2742 1340b Seq. ID No. 2743 Seq. ID No. 2744 1364a Seq. ID No. 2777 Seq. ID No. 2778 1364b Seq. ID No. 2779 Seq. ID No. 2780 1364c Seq. ID No. 2781 Seq. ID No. 2782 1365b Seq. ID No. 2783 Seq. ID No. 2784 1375 Seq. ID No. 2801 Seq. ID No. 2802 1378 Seq. ID No. 2805 Seq. ID No. 2806 1379 Seq. ID No. 2807 Seq. ID No. 2808 1380 Seq. ID No. 2809 Seq. ID No. 2810 1381a Seq. ID No. 2811 Seq. ID No. 2812 1381b Seq. ID No. 2813 Seq. ID No. 2814 1382 Seq. ID No. 2815 Seq. ID No. 2816 1383 Seq. ID No. 2817 Seq. ID No. 2818 1384a Seq. ID No. 2819 Seq. ID No. 2820 1387a Seq. ID No. 2829 Seq. ID No. 2830 1388b Seq. ID No. 2831 Seq. ID No. 2832 1389a Seq. ID No. 2833 Seq. ID No. 2834 1393a Seq. ID No. 2835 Seq. ID No. 2836 1393b Seq. ID No. 2837 Seq. ID No. 2838 1393c Seq. ID No. 2839 Seq. ID No. 2840 1393d Seq. ID No. 2841 Seq. ID No. 2842 1395a Seq. ID No. 2845 Seq. ID No. 2846 1397 Seq. ID No. 2849 Seq. ID No. 2850 1398 Seq. ID No. 2851 Seq. ID No. 2852 1399a Seq. ID No. 2853 Seq. ID No. 2854 1399b Seq. ID No. 2855 Seq. ID No. 2856 1400 Seq. ID No. 2857 Seq. ID No. 2858 1401 Seq. ID No. 2859 Seq. ID No. 2860 1402c Seq. ID No. 2861 Seq. ID No. 2862 1407b Seq. ID No. 2865 Seq. ID No. 2866 1411a Seq. ID No. 2873 Seq. ID No. 2874 1411b Seq. ID No. 2875 Seq. ID No. 2876 1411c Seq. ID No. 2877 Seq. ID No. 2878 1414a Seq. ID No. 2883 Seq. ID No. 2884 1414b Seq. ID No. 2885 Seq. ID No. 2886 1414c Seq. ID No. 2887 Seq. ID No. 2888 1415 Seq. ID No. 2889 Seq. ID No. 2890 1418 Seq. ID No. 2893 Seq. ID No. 2894 1419 Seq. ID No. 2895 Seq. ID No. 2896 1423 Seq. ID No. 2903 Seq. ID No. 2904 1427a Seq. ID No. 2909 Seq. ID No. 2910 1438 Seq. ID No. 2935 Seq. ID No. 2936 1439a Seq. ID No. 2937 Seq. ID No. 2938 1439b Seq. ID No. 2939 Seq. ID No. 2940 1439c Seq. ID No. 2941 Seq. ID No. 2942 1439d Seq. ID No. 2943 Seq. ID No. 2944 1439e Seq. ID No. 2945 Seq. ID No. 2946 1440a Seq. ID No. 2947 Seq. ID No. 2948 1440b Seq. ID No. 2949 Seq. ID No. 2950 1440c Seq. ID No. 2951 Seq. ID No. 2952 1440d Seq. ID No. 2953 Seq. ID No. 2954 1446a Seq. ID No. 2965 Seq. ID No. 2966 1446b Seq. ID No. 2967 Seq. ID No. 2968 1448 Seq. ID No. 2973 Seq. ID No. 2974 1449a Seq. ID No. 2975 Seq. ID No. 2976 1449b Seq. ID No. 2977 Seq. ID No. 2978 1452a Seq. ID No. 2981 Seq. ID No. 2982 1452b Seq. ID No. 2983 Seq. ID No. 2984 1453 Seq. ID No. 2985 Seq. ID No. 2986 1454 Seq. ID No. 2987 Seq. ID No. 2988 1455a Seq. ID No. 2989 Seq. ID No. 2990 1455b Seq. ID No. 2991 Seq. ID No. 2992 1459 Seq. ID No. 3001 Seq. ID No. 3002 1463a Seq. 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ID No. 4097 Seq. ID No. 4098 1961 Seq. ID No. 4113 Seq. ID No. 4114 1966 Seq. ID No. 4123 Seq. ID No. 4124 1970a Seq. ID No. 4131 Seq. ID No. 4132 1970b Seq. ID No. 4133 Seq. ID No. 4134 1972 Seq. ID No. 4135 Seq. ID No. 4136 1976 Seq. ID No. 4139 Seq. ID No. 4140 1980a Seq. ID No. 4151 Seq. ID No. 4152 1980b Seq. ID No. 4153 Seq. ID No. 4154 1981 Seq. ID No. 4155 Seq. ID No. 4156 1991 Seq. ID No. 4181 Seq. ID No. 4182 2016a Seq. ID No. 4221 Seq. ID No. 4222 2023a Seq. ID No. 4241 Seq. ID No. 4242 2025 Seq. ID No. 4253 Seq. ID No. 4254 2030a Seq. ID No. 4257 Seq. ID No. 4258 2030b Seq. ID No. 4259 Seq. ID No. 4260 2030c Seq. ID No. 4261 Seq. ID No. 4262 2030d Seq. ID No. 4263 Seq. ID No. 4264 2032c Seq. ID No. 4265 Seq. ID No. 4266 2035b Seq. ID No. 4269 Seq. ID No. 4270 2038a Seq. ID No. 4275 Seq. ID No. 4276 2040a Seq. ID No. 4277 Seq. ID No. 4278 2042 Seq. ID No. 4279 Seq. ID No. 4280 2043b Seq. ID No. 4281 Seq. ID No. 4282 2045a Seq. ID No. 4285 Seq. ID No. 4286 2045b Seq. 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ID No. 4591 Seq. ID No. 4592 2194a Seq. ID No. 4593 Seq. ID No. 4594 2194c Seq. ID No. 4595 Seq. ID No. 4596 2208a Seq. ID No. 4617 Seq. ID No. 4618 2208b Seq. ID No. 4619 Seq. ID No. 4620 2208c Seq. ID No. 4621 Seq. ID No. 4622 2212a Seq. ID No. 4625 Seq. ID No. 4626 2212b Seq. ID No. 4627 Seq. ID No. 4628 2216a Seq. ID No. 4633 Seq. ID No. 4634 2216b Seq. ID No. 4635 Seq. ID No. 4636 2218 Seq. ID No. 4637 Seq. ID No. 4638 2219a Seq. ID No. 4639 Seq. ID No. 4640 2225 Seq. ID No. 4659 Seq. ID No. 4660 2236a Seq. ID No. 4681 Seq. ID No. 4682 2239b Seq. ID No. 4687 Seq. ID No. 4688 2243a Seq. ID No. 4695 Seq. ID No. 4696 2245 Seq. ID No. 4699 Seq. ID No. 4700 2246 Seq. ID No. 4701 Seq. ID No. 4702 2257 Seq. ID No. 4721 Seq. ID No. 4722 2264a Seq. ID No. 4735 Seq. ID No. 4736 2264b Seq. ID No. 4737 Seq. ID No. 4738 2268 Seq. ID No. 4741 Seq. ID No. 4742 2285 Seq. ID No. 4783 Seq. ID No. 4784 2288 Seq. ID No. 4789 Seq. ID No. 4790 2294 Seq. ID No. 4805 Seq. ID No. 4806 2299 Seq. ID No. 4811 Seq. ID No. 4812 2302 Seq. ID No. 4817 Seq. ID No. 4818 2303 Seq. ID No. 4819 Seq. ID No. 4820 2304 Seq. ID No. 4821 Seq. ID No. 4822 2306c Seq. ID No. 4823 Seq. ID No. 4824 2310 Seq. ID No. 4835 Seq. ID No. 4836 2320 Seq. ID No. 4853 Seq. ID No. 4854 2336 Seq. ID No. 4885 Seq. ID No. 4886 2350a Seq. ID No. 4913 Seq. ID No. 4914 2360 Seq. ID No. 4923 Seq. ID No. 4924 2371a Seq. ID No. 4949 Seq. ID No. 4950 2372 Seq. ID No. 4951 Seq. ID No. 4952 2382c Seq. ID No. 4975 Seq. ID No. 4976 2386b Seq. ID No. 4981 Seq. ID No. 4982 2386c Seq. ID No. 4983 Seq. ID No. 4984 2390 Seq. ID No. 4987 Seq. ID No. 4988 2394 Seq. ID No. 4993 Seq. ID No. 4994 2397 Seq. ID No. 4999 Seq. ID No. 5000 2398 Seq. ID No. 5001 Seq. ID No. 5002 2402a Seq. ID No. 5011 Seq. ID No. 5012 2402b Seq. ID No. 5013 Seq. ID No. 5014 2407a Seq. ID No. 5023 Seq. ID No. 5024 2412 Seq. ID No. 5031 Seq. ID No. 5032 2413a Seq. ID No. 5033 Seq. ID No. 5034 2413b Seq. ID No. 5035 Seq. ID No. 5036 2415a Seq. 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ID No. 5237 Seq. ID No. 5238 2518a Seq. ID No. 5267 Seq. ID No. 5268 2519a Seq. ID No. 5269 Seq. ID No. 5270 2519b Seq. ID No. 5271 Seq. ID No. 5272 2521 Seq. ID No. 5281 Seq. ID No. 5282 2532b Seq. ID No. 5301 Seq. ID No. 5302 2532c Seq. ID No. 5303 Seq. ID No. 5304 2542a Seq. ID No. 5315 Seq. ID No. 5316 2543 Seq. ID No. 5321 Seq. ID No. 5322 2546 Seq. ID No. 5327 Seq. ID No. 5328 2553 Seq. ID No. 5347 Seq. ID No. 5348 2567a Seq. ID No. 5385 Seq. ID No. 5386 2605a Seq. ID No. 5445 Seq. ID No. 5446 2605b Seq. ID No. 5447 Seq. ID No. 5448 2616a Seq. ID No. 5459 Seq. ID No. 5460 2616d Seq. ID No. 5465 Seq. ID No. 5466 2616e Seq. ID No. 5467 Seq. ID No. 5468 2618a Seq. ID No. 5479 Seq. ID No. 5480 2618b Seq. ID No. 5481 Seq. ID No. 5482 2620 Seq. ID No. 5485 Seq. ID No. 5486 2621a Seq. ID No. 5487 Seq. ID No. 5488 2631 Seq. ID No. 5515 Seq. ID No. 5516 2632 Seq. ID No. 5517 Seq. ID No. 5518 2642 Seq. ID No. 5533 Seq. ID No. 5534 2648a Seq. ID No. 5543 Seq. ID No. 5544 2648b Seq. ID No. 5545 Seq. ID No. 5546 2650 Seq. ID No. 5549 Seq. ID No. 5550 2660 Seq. ID No. 5569 Seq. ID No. 5570 2665 Seq. ID No. 5577 Seq. ID No. 5578 2672 Seq. ID No. 5593 Seq. ID No. 5594 2673 Seq. ID No. 5595 Seq. ID No. 5596 2679a Seq. ID No. 5609 Seq. ID No. 5610 2683a Seq. ID No. 5623 Seq. ID No. 5624 2683b Seq. ID No. 5625 Seq. ID No. 5626 2689a Seq. ID No. 5639 Seq. ID No. 5640 2689b Seq. ID No. 5641 Seq. ID No. 5642 2690a Seq. ID No. 5643 Seq. ID No. 5644 2692b Seq. ID No. 5649 Seq. ID No. 5650 2696a Seq. ID No. 5659 Seq. ID No. 5660 2696b Seq. ID No. 5661 Seq. ID No. 5662 2705 Seq. ID No. 5663 Seq. ID No. 5664 2710c Seq. ID No. 5667 Seq. ID No. 5668 2713 Seq. ID No. 5671 Seq. ID No. 5672 2719a Seq. ID No. 5687 Seq. ID No. 5688 2719b Seq. ID No. 5689 Seq. ID No. 5690 2725a Seq. ID No. 5703 Seq. ID No. 5704 2725b Seq. ID No. 5705 Seq. ID No. 5706 2728a Seq. ID No. 5709 Seq. ID No. 5710 2728b Seq. ID No. 5711 Seq. ID No. 5712 2742a Seq. ID No. 5737 Seq. ID No. 5738 2742b Seq. ID No. 5739 Seq. ID No. 5740 2744 Seq. ID No. 5745 Seq. ID No. 5746 2746 Seq. ID No. 5751 Seq. ID No. 5752 2749a Seq. ID No. 5763 Seq. ID No. 5764 2760a Seq. ID No. 5797 Seq. ID No. 5798 2764 Seq. ID No. 5811 Seq. ID No. 5812 2765b Seq. ID No. 5813 Seq. ID No. 5814 2765c Seq. ID No. 5815 Seq. ID No. 5816 2769a Seq. ID No. 5827 Seq. ID No. 5828 2770 Seq. ID No. 5829 Seq. ID No. 5830 2776a Seq. ID No. 5843 Seq. ID No. 5844 2776b Seq. ID No. 5845 Seq. ID No. 5846 2788b Seq. ID No. 5873 Seq. ID No. 5874 2791 Seq. ID No. 5879 Seq. ID No. 5880 2794 Seq. ID No. 5883 Seq. ID No. 5884 2796a Seq. ID No. 5885 Seq. ID No. 5886 2798 Seq. ID No. 5887 Seq. ID No. 5888 2799a Seq. ID No. 5889 Seq. ID No. 5890 2799b Seq. ID No. 5891 Seq. ID No. 5892 2819 Seq. ID No. 5931 Seq. ID No. 5932 2832 Seq. ID No. 5955 Seq. ID No. 5956 2837a Seq. ID No. 5963 Seq. ID No. 5964 2837b Seq. ID No. 5965 Seq. ID No. 5966 2845 Seq. ID No. 5975 Seq. ID No. 5976 2850 Seq. ID No. 5983 Seq. ID No. 5984 2851 Seq. ID No. 5985 Seq. ID No. 5986 2852 Seq. ID No. 5987 Seq. ID No. 5988 2853 Seq. ID No. 5989 Seq. ID No. 5990 2859 Seq. ID No. 6005 Seq. ID No. 6006 2862 Seq. ID No. 6013 Seq. ID No. 6014 2872 Seq. ID No. 6031 Seq. ID No. 6032 2877 Seq. ID No. 6035 Seq. ID No. 6036 2882 Seq. ID No. 6045 Seq. ID No. 6046 2887a Seq. ID No. 6059 Seq. ID No. 6060 2887b Seq. ID No. 6061 Seq. ID No. 6062 2888 Seq. ID No. 6063 Seq. ID No. 6064 2893b Seq. ID No. 6073 Seq. ID No. 6074 2895 Seq. ID No. 6081 Seq. ID No. 6082 2901a Seq. ID No. 6091 Seq. ID No. 6092 2901b Seq. ID No. 6093 Seq. ID No. 6094 2917 Seq. ID No. 6127 Seq. ID No. 6128 2929b Seq. ID No. 6159 Seq. ID No. 6160 2944b Seq. ID No. 6197 Seq. ID No. 6198 2945b Seq. ID No. 6199 Seq. ID No. 6200 2948a Seq. ID No. 6203 Seq. ID No. 6204 2952 Seq. ID No. 6217 Seq. ID No. 6218 2955a Seq. ID No. 6221 Seq. ID No. 6222 2955b Seq. ID No. 6223 Seq. ID No. 6224 2958a Seq. ID No. 6237 Seq. ID No. 6238 2958b Seq. ID No. 6239 Seq. ID No. 6240 2958c Seq. ID No. 6241 Seq. ID No. 6242 2960a Seq. ID No. 6245 Seq. ID No. 6246 2962a Seq. ID No. 6247 Seq. ID No. 6248 2962b Seq. ID No. 6249 Seq. ID No. 6250 2966 Seq. ID No. 6259 Seq. ID No. 6260 2970a Seq. ID No. 6265 Seq. ID No. 6266 2970b Seq. ID No. 6267 Seq. ID No. 6268 2974a Seq. ID No. 6273 Seq. ID No. 6274 2978a Seq. ID No. 6283 Seq. ID No. 6284 2978b Seq. ID No. 6285 Seq. ID No. 6286 2992 Seq. ID No. 6323 Seq. ID No. 6324 2993a Seq. ID No. 6325 Seq. ID No. 6326 2993b Seq. ID No. 6327 Seq. ID No. 6328 3015 Seq. ID No. 6361 Seq. ID No. 6362 3016a Seq. ID No. 6363 Seq. ID No. 6364 3021 Seq. ID No. 6377 Seq. ID No. 6378 3023 Seq. ID No. 6381 Seq. ID No. 6382 3031a Seq. ID No. 6401 Seq. ID No. 6402 3031b Seq. ID No. 6403 Seq. ID No. 6404 3038 Seq. ID No. 6419 Seq. ID No. 6420 3042a Seq. ID No. 6425 Seq. ID No. 6426 3042b Seq. ID No. 6427 Seq. ID No. 6428 3043a Seq. ID No. 6429 Seq. ID No. 6430 3043b Seq. ID No. 6431 Seq. ID No. 6432 3044 Seq. ID No. 6433 Seq. ID No. 6434 3045a Seq. ID No. 6435 Seq. ID No. 6436 3045b Seq. ID No. 6437 Seq. ID No. 6438 3048a Seq. ID No. 6439 Seq. ID No. 6440 3051a Seq. ID No. 6447 Seq. ID No. 6448 3051b Seq. ID No. 6449 Seq. ID No. 6450 3052 Seq. ID No. 6451 Seq. ID No. 6452 3054 Seq. ID No. 6453 Seq. ID No. 6454 3055a Seq. ID No. 6455 Seq. ID No. 6456 3055b Seq. ID No. 6457 Seq. ID No. 6458 3061 Seq. ID No. 6465 Seq. ID No. 6466 3062 Seq. ID No. 6467 Seq. ID No. 6468 3063a Seq. ID No. 6469 Seq. ID No. 6470 3063b Seq. ID No. 6471 Seq. ID No. 6472 3064b Seq. ID No. 6473 Seq. ID No. 6474 3065a Seq. ID No. 6475 Seq. ID No. 6476 3065b Seq. ID No. 6477 Seq. ID No. 6478 3066 Seq. ID No. 6479 Seq. ID No. 6480 3067 Seq. ID No. 6481 Seq. ID No. 6482 3068 Seq. ID No. 6483 Seq. ID No. 6484 3069 Seq. ID No. 6485 Seq. ID No. 6486 3071 Seq. ID No. 6487 Seq. ID No. 6488 3072a Seq. ID No. 6489 Seq. ID No. 6490 3073 Seq. ID No. 6491 Seq. ID No. 6492 3075 Seq. ID No. 6495 Seq. ID No. 6496 3076 Seq. ID No. 6497 Seq. ID No. 6498 3079 Seq. ID No. 6507 Seq. ID No. 6508 3085 Seq. ID No. 6517 Seq. ID No. 6518 3086 Seq. ID No. 6519 Seq. ID No. 6520 3087a Seq. ID No. 6521 Seq. ID No. 6522 3087c Seq. ID No. 6523 Seq. ID No. 6524 3088 Seq. ID No. 6525 Seq. ID No. 6526 3089a Seq. ID No. 6527 Seq. ID No. 6528 3089b Seq. ID No. 6529 Seq. ID No. 6530 3091 Seq. ID No. 6533 Seq. ID No. 6534 3095 Seq. ID No. 6539 Seq. ID No. 6540 3096a Seq. ID No. 6541 Seq. ID No. 6542 3096b Seq. ID No. 6543 Seq. ID No. 6544 3100a Seq. ID No. 6555 Seq. ID No. 6556 3100b Seq. ID No. 6557 Seq. ID No. 6558 3102 Seq. ID No. 6561 Seq. ID No. 6562 3103b Seq. ID No. 6563 Seq. ID No. 6564 3104 Seq. ID No. 6565 Seq. ID No. 6566 3105 Seq. ID No. 6567 Seq. ID No. 6568 3106 Seq. ID No. 6569 Seq. ID No. 6570 3107a Seq. ID No. 6571 Seq. ID No. 6572 3107b Seq. ID No. 6573 Seq. ID No. 6574 3110a Seq. ID No. 6581 Seq. ID No. 6582 3110b Seq. ID No. 6583 Seq. ID No. 6584 3140 Seq. ID No. 6631 Seq. ID No. 6632 3145a Seq. ID No. 6635 Seq. ID No. 6636 3145b Seq. ID No. 6637 Seq. ID No. 6638 3145c Seq. ID No. 6639 Seq. ID No. 6640 3147b Seq. ID No. 6643 Seq. ID No. 6644 3147c Seq. ID No. 6645 Seq. ID No. 6646 3149a Seq. ID No. 6647 Seq. ID No. 6648 3150a Seq. ID No. 6649 Seq. ID No. 6650

Listed in Table 18 are 1529 ORFs detected by the Glimmer™ ORF finder program. TABLE 18 GLIMMER ™ ORFs ORF Number DNA SEQ ID Number Protein SEQ ID Number 1 Seq. ID No. 1 Seq. ID No. 2 2b Seq. ID No. 5 Seq. ID No. 6 4c Seq. ID No. 11 Seq. ID No. 12 5 Seq. ID No. 13 Seq. ID No. 14 7 Seq. ID No. 15 Seq. ID No. 16 10 Seq. ID No. 17 Seq. ID No. 18 17 Seq. ID No. 25 Seq. ID No. 26 18 Seq. ID No. 27 Seq. ID No. 28 20 Seq. ID No. 29 Seq. ID No. 30 23b Seq. ID No. 35 Seq. ID No. 36 24 Seq. ID No. 37 Seq. ID No. 38 36 Seq. ID No. 41 Seq. ID No. 42 37 Seq. ID No. 43 Seq. ID No. 44 38b Seq. ID No. 47 Seq. ID No. 48 39b Seq. ID No. 51 Seq. ID No. 52 40 Seq. ID No. 53 Seq. ID No. 54 41c Seq. ID No. 59 Seq. ID No. 60 43c Seq. ID No. 63 Seq. ID No. 64 45 Seq. ID No. 69 Seq. ID No. 70 46b Seq. ID No. 73 Seq. ID No. 74 47 Seq. ID No. 75 Seq. ID No. 76 48c Seq. ID No. 81 Seq. ID No. 82 50 Seq. ID No. 83 Seq. ID No. 84 51c Seq. ID No. 89 Seq. ID No. 90 56b Seq. ID No. 93 Seq. ID No. 94 57b Seq. ID No. 97 Seq. ID No. 98 60b Seq. ID No. 103 Seq. ID No. 104 62c Seq. ID No. 111 Seq. ID No. 112 65c Seq. ID No. 121 Seq. ID No. 122 67 Seq. ID No. 125 Seq. ID No. 126 71 Seq. ID No. 129 Seq. ID No. 130 74 Seq. ID No. 135 Seq. ID No. 136 77 Seq. ID No. 137 Seq. ID No. 138 80c Seq. ID No. 145 Seq. ID No. 146 81b Seq. ID No. 149 Seq. ID No. 150 85c Seq. ID No. 157 Seq. ID No. 158 88 Seq. ID No. 167 Seq. ID No. 168 91b Seq. ID No. 173 Seq. ID No. 174 93c Seq. ID No. 183 Seq. ID No. 184 95b Seq. ID No. 187 Seq. ID No. 188 97b Seq. ID No. 189 Seq. ID No. 190 99 Seq. ID No. 191 Seq. ID No. 192 102 Seq. ID No. 195 Seq. ID No. 196 104a Seq. ID No. 197 Seq. ID No. 198 105a Seq. ID No. 203 Seq. ID No. 204 106 Seq. ID No. 207 Seq. ID No. 208 109d Seq. ID No. 215 Seq. ID No. 216 111b Seq. ID No. 219 Seq. ID No. 220 112b Seq. ID No. 223 Seq. ID No. 224 114 Seq. ID No. 225 Seq. ID No. 226 115 Seq. ID No. 227 Seq. ID No. 228 119b Seq. ID No. 231 Seq. ID No. 232 121 Seq. ID No. 233 Seq. ID No. 234 124c Seq. ID No. 239 Seq. ID No. 240 125 Seq. ID No. 241 Seq. ID No. 242 127c Seq. ID No. 247 Seq. ID No. 248 129c Seq. ID No. 253 Seq. ID No. 254 134 Seq. ID No. 261 Seq. ID No. 262 135b Seq. ID No. 265 Seq. ID No. 266 137b Seq. ID No. 269 Seq. ID No. 270 138b Seq. ID No. 273 Seq. ID No. 274 142 Seq. ID No. 275 Seq. ID No. 276 143 Seq. ID No. 277 Seq. ID No. 278 144c Seq. ID No. 283 Seq. ID No. 284 145d Seq. ID No. 291 Seq. ID No. 292 147 Seq. ID No. 293 Seq. ID No. 294 151b Seq. ID No. 297 Seq. ID No. 298 152b Seq. ID No. 301 Seq. ID No. 302 153c Seq. ID No. 307 Seq. ID No. 308 154 Seq. ID No. 309 Seq. ID No. 310 155b Seq. ID No. 313 Seq. ID No. 314 157b Seq. ID No. 317 Seq. ID No. 318 158b Seq. ID No. 321 Seq. ID No. 322 160b Seq. ID No. 325 Seq. ID No. 326 162e Seq. ID No. 335 Seq. ID No. 336 165b Seq. ID No. 343 Seq. ID No. 344 167 Seq. ID No. 345 Seq. ID No. 346 171b Seq. ID No. 353 Seq. ID No. 354 172 Seq. ID No. 355 Seq. ID No. 356 175 Seq. ID No. 361 Seq. ID No. 362 176 Seq. ID No. 363 Seq. ID No. 364 177b Seq. ID No. 367 Seq. ID No. 368 180b Seq. ID No. 375 Seq. ID No. 376 184 Seq. ID No. 379 Seq. ID No. 380 186 Seq. ID No. 383 Seq. ID No. 384 188 Seq. ID No. 389 Seq. ID No. 390 189b Seq. ID No. 391 Seq. ID No. 392 192b Seq. ID No. 397 Seq. ID No. 398 195 Seq. ID No. 405 Seq. ID No. 406 197b Seq. ID No. 411 Seq. ID No. 412 198b Seq. ID No. 415 Seq. ID No. 416 200 Seq. ID No. 417 Seq. ID No. 418 203 Seq. ID No. 423 Seq. ID No. 424 204 Seq. ID No. 425 Seq. ID No. 426 205 Seq. ID No. 427 Seq. ID No. 428 206 Seq. ID No. 429 Seq. ID No. 430 208b Seq. ID No. 435 Seq. ID No. 436 210 Seq. ID No. 437 Seq. ID No. 438 211 Seq. ID No. 439 Seq. ID No. 440 213 Seq. ID No. 441 Seq. ID No. 442 218 Seq. ID No. 445 Seq. ID No. 446 219 Seq. ID No. 447 Seq. ID No. 448 220c Seq. ID No. 453 Seq. ID No. 454 226b Seq. ID No. 461 Seq. ID No. 462 227 Seq. ID No. 463 Seq. ID No. 464 228d Seq. ID No. 471 Seq. ID No. 472 236c Seq. ID No. 485 Seq. ID No. 486 245c Seq. ID No. 501 Seq. ID No. 502 246b Seq. ID No. 505 Seq. ID No. 506 248b Seq. ID No. 511 Seq. ID No. 512 249b Seq. ID No. 515 Seq. ID No. 516 251 Seq. ID No. 517 Seq. ID No. 518 253b Seq. ID No. 521 Seq. ID No. 522 254 Seq. ID No. 523 Seq. ID No. 524 255d Seq. ID No. 531 Seq. ID No. 532 258 Seq. ID No. 533 Seq. ID No. 534 259c Seq. ID No. 539 Seq. ID No. 540 260 Seq. ID No. 541 Seq. ID No. 542 262 Seq. ID No. 543 Seq. ID No. 544 265 Seq. ID No. 551 Seq. ID No. 552 267c Seq. ID No. 555 Seq. ID No. 556 269b Seq. ID No. 561 Seq. ID No. 562 271b Seq. ID No. 565 Seq. ID No. 566 273b Seq. ID No. 569 Seq. ID No. 570 277c Seq. ID No. 575 Seq. ID No. 576 279b Seq. ID No. 579 Seq. ID No. 580 280d Seq. ID No. 587 Seq. ID No. 588 283b Seq. ID No. 593 Seq. ID No. 594 284b Seq. ID No. 597 Seq. ID No. 598 286b Seq. ID No. 603 Seq. ID No. 604 287 Seq. ID No. 605 Seq. ID No. 606 290b Seq. ID No. 609 Seq. ID No. 610 293 Seq. ID No. 611 Seq. ID No. 612 294 Seq. ID No. 613 Seq. ID No. 614 296 Seq. ID No. 615 Seq. ID No. 616 301b Seq. ID No. 623 Seq. ID No. 624 304b Seq. ID No. 627 Seq. ID No. 628 307 Seq. ID No. 629 Seq. ID No. 630 308 Seq. ID No. 631 Seq. ID No. 632 310 Seq. ID No. 635 Seq. ID No. 636 311 Seq. ID No. 637 Seq. ID No. 638 313e Seq. ID No. 647 Seq. ID No. 648 315 Seq. ID No. 649 Seq. ID No. 650 318c Seq. ID No. 661 Seq. ID No. 662 321 Seq. ID No. 669 Seq. ID No. 670 323b Seq. ID No. 673 Seq. ID No. 674 324 Seq. ID No. 675 Seq. ID No. 676 327c Seq. ID No. 681 Seq. ID No. 682 329 Seq. ID No. 683 Seq. ID No. 684 330c Seq. ID No. 689 Seq. ID No. 690 335b Seq. ID No. 701 Seq. ID No. 702 337 Seq. ID No. 703 Seq. ID No. 704 338c Seq. ID No. 709 Seq. ID No. 710 341b Seq. ID No. 713 Seq. ID No. 714 342h Seq. ID No. 729 Seq. ID No. 730 344b Seq. ID No. 733 Seq. ID No. 734 345 Seq. ID No. 735 Seq. ID No. 736 346a Seq. ID No. 737 Seq. ID No. 738 347 Seq. ID No. 741 Seq. ID No. 742 349c Seq. ID No. 747 Seq. ID No. 748 350b Seq. ID No. 751 Seq. ID No. 752 351 Seq. ID No. 753 Seq. ID No. 754 352c Seq. ID No. 759 Seq. ID No. 760 354c Seq. ID No. 765 Seq. ID No. 766 355 Seq. ID No. 767 Seq. ID No. 768 356b Seq. ID No. 771 Seq. ID No. 772 358c Seq. ID No. 781 Seq. ID No. 782 362 Seq. ID No. 783 Seq. ID No. 784 365b Seq. ID No. 787 Seq. ID No. 788 366c Seq. ID No. 791 Seq. ID No. 792 367b Seq. ID No. 795 Seq. ID No. 796 371b Seq. ID No. 799 Seq. ID No. 800 372d Seq. ID No. 807 Seq. ID No. 808 378b Seq. ID No. 817 Seq. ID No. 818 382b Seq. ID No. 819 Seq. ID No. 820 383b Seq. ID No. 823 Seq. ID No. 824 384b Seq. ID No. 827 Seq. ID No. 828 385b Seq. ID No. 831 Seq. ID No. 832 387 Seq. ID No. 835 Seq. ID No. 836 390 Seq. ID No. 837 Seq. ID No. 838 391 Seq. ID No. 839 Seq. ID No. 840 395c Seq. ID No. 847 Seq. ID No. 848 398 Seq. ID No. 851 Seq. ID No. 852 400b Seq. ID No. 855 Seq. ID No. 856 401b Seq. ID No. 859 Seq. ID No. 860 403d Seq. ID No. 867 Seq. ID No. 868 406b Seq. ID No. 871 Seq. ID No. 872 409b Seq. ID No. 875 Seq. ID No. 876 410c Seq. ID No. 881 Seq. ID No. 882 413b Seq. ID No. 885 Seq. ID No. 886 416b Seq. ID No. 889 Seq. ID No. 890 417 Seq. ID No. 891 Seq. ID No. 892 418b Seq. ID No. 895 Seq. ID No. 896 419c Seq. ID No. 901 Seq. ID No. 902 421 Seq. ID No. 907 Seq. ID No. 908 424c Seq. ID No. 915 Seq. ID No. 916 426b Seq. ID No. 919 Seq. ID No. 920 427c Seq. ID No. 925 Seq. ID No. 926 429b Seq. ID No. 929 Seq. ID No. 930 431 Seq. ID No. 935 Seq. ID No. 936 435 Seq. ID No. 939 Seq. ID No. 940 438c Seq. ID No. 949 Seq. ID No. 950 440 Seq. ID No. 951 Seq. ID No. 952 441b Seq. ID No. 955 Seq. ID No. 956 444b Seq. ID No. 961 Seq. ID No. 962 445b Seq. ID No. 965 Seq. ID No. 966 448 Seq. ID No. 967 Seq. ID No. 968 450b Seq. ID No. 971 Seq. ID No. 972 452e Seq. ID No. 985 Seq. ID No. 986 455c Seq. ID No. 993 Seq. ID No. 994 458b Seq. ID No. 997 Seq. ID No. 998 460c Seq. ID No. 1003 Seq. ID No. 1004 462 Seq. ID No. 1005 Seq. ID No. 1006 463b Seq. ID No. 1009 Seq. ID No. 1010 464d Seq. ID No. 1017 Seq. ID No. 1018 467b Seq. ID No. 1023 Seq. ID No. 1024 472f Seq. ID No. 1039 Seq. ID No. 1040 473 Seq. ID No. 1041 Seq. ID No. 1042 474 Seq. ID No. 1043 Seq. ID No. 1044 478b Seq. ID No. 1051 Seq. ID No. 1052 479 Seq. ID No. 1053 Seq. ID No. 1054 480b Seq. ID No. 1057 Seq. ID No. 1058 481b Seq. ID No. 1061 Seq. ID No. 1062 482b Seq. ID No. 1065 Seq. ID No. 1066 483 Seq. ID No. 1067 Seq. ID No. 1068 490 Seq. ID No. 1069 Seq. ID No. 1070 491b Seq. ID No. 1073 Seq. ID No. 1074 492 Seq. ID No. 1075 Seq. ID No. 1076 495c Seq. ID No. 1083 Seq. ID No. 1084 498b Seq. ID No. 1087 Seq. ID No. 1088 499b Seq. ID No. 1091 Seq. ID No. 1092 500 Seq. ID No. 1093 Seq. ID No. 1094 502c Seq. ID No. 1097 Seq. ID No. 1098 504 Seq. ID No. 1099 Seq. ID No. 1100 505b Seq. ID No. 1103 Seq. ID No. 1104 509 Seq. ID No. 1109 Seq. ID No. 1110 512b Seq. ID No. 1115 Seq. ID No. 1116 514 Seq. ID No. 1117 Seq. ID No. 1118 515c Seq. ID No. 1123 Seq. ID No. 1124 518c Seq. ID No. 1129 Seq. ID No. 1130 523 Seq. ID No. 1133 Seq. ID No. 1134 524b Seq. ID No. 1137 Seq. ID No. 1138 527b Seq. ID No. 1143 Seq. ID No. 1144 528b Seq. ID No. 1147 Seq. ID No. 1148 529 Seq. ID No. 1149 Seq. ID No. 1150 533 Seq. ID No. 1155 Seq. ID No. 1156 535 Seq. ID No. 1157 Seq. ID No. 1158 536 Seq. ID No. 1159 Seq. ID No. 1160 539c Seq. ID No. 1163 Seq. ID No. 1164 541d Seq. ID No. 1171 Seq. ID No. 1172 543c Seq. ID No. 1179 Seq. ID No. 1180 544 Seq. ID No. 1181 Seq. ID No. 1182 545c Seq. ID No. 1187 Seq. ID No. 1188 546c Seq. ID No. 1193 Seq. ID No. 1194 548 Seq. ID No. 1199 Seq. ID No. 1200 551 Seq. ID No. 1205 Seq. ID No. 1206 554b Seq. ID No. 1211 Seq. ID No. 1212 557b Seq. ID No. 1217 Seq. ID No. 1218 560b Seq. ID No. 1221 Seq. ID No. 1222 561 Seq. ID No. 1223 Seq. ID No. 1224 563 Seq. ID No. 1225 Seq. ID No. 1226 564c Seq. ID No. 1231 Seq. ID No. 1232 569 Seq. ID No. 1233 Seq. ID No. 1234 570b Seq. ID No. 1237 Seq. ID No. 1238 573 Seq. ID No. 1241 Seq. ID No. 1242 580b Seq. ID No. 1253 Seq. 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ID No. 4543 Seq. ID No. 4544 2173b Seq. ID No. 4547 Seq. ID No. 4548 2174 Seq. ID No. 4549 Seq. ID No. 4550 2176d Seq. ID No. 4559 Seq. ID No. 4560 2179b Seq. ID No. 4565 Seq. ID No. 4566 2180 Seq. ID No. 4567 Seq. ID No. 4568 2181b Seq. ID No. 4571 Seq. ID No. 4572 2183 Seq. ID No. 4575 Seq. ID No. 4576 2185 Seq. ID No. 4577 Seq. ID No. 4578 2186b Seq. ID No. 4581 Seq. ID No. 4582 2189b Seq. ID No. 4585 Seq. ID No. 4586 2193 Seq. ID No. 4591 Seq. ID No. 4592 2194c Seq. ID No. 4595 Seq. ID No. 4596 2196 Seq. ID No. 4597 Seq. ID No. 4598 2197c Seq. ID No. 4603 Seq. ID No. 4604 2201b Seq. ID No. 4607 Seq. ID No. 4608 2203 Seq. ID No. 4609 Seq. ID No. 4610 2204 Seq. ID No. 4611 Seq. ID No. 4612 2206b Seq. ID No. 4615 Seq. ID No. 4616 2209 Seq. ID No. 4623 Seq. ID No. 4624 2212b Seq. ID No. 4627 Seq. ID No. 4628 2215b Seq. ID No. 4631 Seq. ID No. 4632 2216b Seq. ID No. 4635 Seq. ID No. 4636 2218 Seq. ID No. 4637 Seq. ID No. 4638 2219c Seq. ID No. 4643 Seq. ID No. 4644 2220c Seq. ID No. 4649 Seq. ID No. 4650 2221 Seq. ID No. 4651 Seq. ID No. 4652 2222 Seq. ID No. 4653 Seq. ID No. 4654 2223b Seq. ID No. 4657 Seq. ID No. 4658 2226 Seq. ID No. 4661 Seq. ID No. 4662 2227 Seq. ID No. 4663 Seq. ID No. 4664 2228c Seq. ID No. 4669 Seq. ID No. 4670 2231 Seq. ID No. 4671 Seq. ID No. 4672 2232 Seq. ID No. 4673 Seq. ID No. 4674 2234c Seq. ID No. 4679 Seq. ID No. 4680 2238 Seq. ID No. 4685 Seq. ID No. 4686 2240c Seq. ID No. 4693 Seq. ID No. 4694 2244 Seq. ID No. 4697 Seq. ID No. 4698 2248 Seq. ID No. 4703 Seq. ID No. 4704 2249 Seq. ID No. 4705 Seq. ID No. 4706 2253d Seq. ID No. 4713 Seq. ID No. 4714 2255b Seq. ID No. 4717 Seq. ID No. 4718 2256 Seq. ID No. 4719 Seq. ID No. 4720 2259b Seq. ID No. 4725 Seq. ID No. 4726 2260c Seq. ID No. 4729 Seq. ID No. 4730 2262 Seq. ID No. 4731 Seq. ID No. 4732 2263 Seq. ID No. 4733 Seq. ID No. 4734 2267 Seq. ID No. 4739 Seq. ID No. 4740 2269 Seq. ID No. 4743 Seq. ID No. 4744 2270 Seq. ID No. 4745 Seq. ID No. 4746 2272 Seq. ID No. 4747 Seq. ID No. 4748 2273 Seq. ID No. 4749 Seq. ID No. 4750 2274 Seq. ID No. 4751 Seq. ID No. 4752 2275c Seq. ID No. 4757 Seq. ID No. 4758 2276d Seq. ID No. 4765 Seq. ID No. 4766 2277b Seq. ID No. 4769 Seq. ID No. 4770 2278d Seq. ID No. 4777 Seq. ID No. 4778 2280 Seq. ID No. 4779 Seq. ID No. 4780 2284 Seq. ID No. 4781 Seq. ID No. 4782 2286b Seq. ID No. 4787 Seq. ID No. 4788 2288 Seq. ID No. 4789 Seq. ID No. 4790 2290 Seq. ID No. 4791 Seq. ID No. 4792 2291c Seq. ID No. 4797 Seq. ID No. 4798 2292c Seq. ID No. 4803 Seq. ID No. 4804 2297 Seq. ID No. 4807 Seq. ID No. 4808 2298 Seq. ID No. 4809 Seq. ID No. 4810 2299 Seq. ID No. 4811 Seq. ID No. 4812 2300 Seq. ID No. 4813 Seq. ID No. 4814 2301 Seq. ID No. 4815 Seq. ID No. 4816 2304 Seq. ID No. 4821 Seq. ID No. 4822 2306c Seq. ID No. 4823 Seq. ID No. 4824 2307 Seq. ID No. 4825 Seq. ID No. 4826 2308 Seq. ID No. 4827 Seq. ID No. 4828 2309c Seq. ID No. 4833 Seq. ID No. 4834 2310 Seq. ID No. 4835 Seq. ID No. 4836 2311 Seq. ID No. 4837 Seq. ID No. 4838 2312c Seq. ID No. 4843 Seq. ID No. 4844 2314 Seq. ID No. 4845 Seq. ID No. 4846 2315 Seq. ID No. 4847 Seq. ID No. 4848 2316 Seq. ID No. 4849 Seq. ID No. 4850 2321c Seq. ID No. 4859 Seq. ID No. 4860 2322 Seq. ID No. 4861 Seq. ID No. 4862 2327 Seq. ID No. 4865 Seq. ID No. 4866 2328 Seq. ID No. 4867 Seq. ID No. 4868 2329d Seq. ID No. 4875 Seq. ID No. 4876 2330 Seq. ID No. 4877 Seq. ID No. 4878 2331 Seq. ID No. 4879 Seq. ID No. 4880 2333 Seq. ID No. 4881 Seq. ID No. 4882 2335 Seq. ID No. 4883 Seq. ID No. 4884 2336 Seq. ID No. 4885 Seq. ID No. 4886 2337b Seq. ID No. 4887 Seq. ID No. 4888 2338c Seq. ID No. 4893 Seq. ID No. 4894 2342c Seq. ID No. 4899 Seq. ID No. 4900 2344 Seq. ID No. 4901 Seq. ID No. 4902 2345 Seq. ID No. 4903 Seq. ID No. 4904 2347 Seq. ID No. 4905 Seq. ID No. 4906 2348 Seq. ID No. 4907 Seq. ID No. 4908 2349b Seq. ID No. 4911 Seq. ID No. 4912 2353 Seq. ID No. 4915 Seq. ID No. 4916 2354 Seq. ID No. 4917 Seq. ID No. 4918 2357 Seq. ID No. 4919 Seq. ID No. 4920 2358 Seq. ID No. 4921 Seq. ID No. 4922 2361b Seq. ID No. 4927 Seq. ID No. 4928 2363b Seq. ID No. 4931 Seq. ID No. 4932 2365b Seq. ID No. 4935 Seq. ID No. 4936 2366b Seq. ID No. 4939 Seq. ID No. 4940 2367 Seq. ID No. 4941 Seq. ID No. 4942 2368 Seq. ID No. 4943 Seq. ID No. 4944 2369 Seq. ID No. 4945 Seq. ID No. 4946 2370 Seq. ID No. 4947 Seq. ID No. 4948 2373 Seq. ID No. 4953 Seq. ID No. 4954 2374b Seq. ID No. 4957 Seq. ID No. 4958 2376 Seq. ID No. 4959 Seq. ID No. 4960 2377b Seq. ID No. 4963 Seq. ID No. 4964 2378 Seq. ID No. 4965 Seq. ID No. 4966 2379b Seq. ID No. 4969 Seq. ID No. 4970 2380 Seq. ID No. 4971 Seq. ID No. 4972 2381 Seq. ID No. 4973 Seq. ID No. 4974 2384b Seq. ID No. 4979 Seq. ID No. 4980 2387 Seq. ID No. 4985 Seq. ID No. 4986 2391 Seq. ID No. 4989 Seq. ID No. 4990 2392 Seq. ID No. 4991 Seq. ID No. 4992 2395 Seq. ID No. 4995 Seq. ID No. 4996 2396 Seq. ID No. 4997 Seq. ID No. 4998 2398 Seq. ID No. 5001 Seq. ID No. 5002 2399c Seq. ID No. 5007 Seq. 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ID No. 5220 2500c Seq. ID No. 5227 Seq. ID No. 5228 2501b Seq. ID No. 5231 Seq. ID No. 5232 2504b Seq. ID No. 5235 Seq. ID No. 5236 2505 Seq. ID No. 5237 Seq. ID No. 5238 2506 Seq. ID No. 5239 Seq. ID No. 5240 2507c Seq. ID No. 5243 Seq. ID No. 5244 2510 Seq. ID No. 5245 Seq. ID No. 5246 2512c Seq. ID No. 5247 Seq. ID No. 5248 2513c Seq. ID No. 5253 Seq. ID No. 5254 2514 Seq. ID No. 5255 Seq. ID No. 5256 2515 Seq. ID No. 5257 Seq. ID No. 5258 2516b Seq. ID No. 5261 Seq. ID No. 5262 2517a Seq. ID No. 5263 Seq. ID No. 5264 2519b Seq. ID No. 5271 Seq. ID No. 5272 2520b Seq. ID No. 5275 Seq. ID No. 5276 2523 Seq. ID No. 5283 Seq. ID No. 5284 2527b Seq. ID No. 5291 Seq. ID No. 5292 2528d Seq. ID No. 5299 Seq. ID No. 5300 2534 Seq. ID No. 5305 Seq. ID No. 5306 2535b Seq. ID No. 5309 Seq. ID No. 5310 2538 Seq. ID No. 5311 Seq. ID No. 5312 2541 Seq. ID No. 5313 Seq. ID No. 5314 2542c Seq. ID No. 5319 Seq. ID No. 5320 2544 Seq. ID No. 5323 Seq. ID No. 5324 2545 Seq. ID No. 5325 Seq. 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ID No. 5860 2786c Seq. ID No. 5865 Seq. ID No. 5866 2787c Seq. ID No. 5871 Seq. ID No. 5872 2789 Seq. ID No. 5875 Seq. ID No. 5876 2790 Seq. ID No. 5877 Seq. ID No. 5878 2793 Seq. ID No. 5881 Seq. ID No. 5882 2798 Seq. ID No. 5887 Seq. ID No. 5888 2799b Seq. ID No. 5891 Seq. ID No. 5892 2801b Seq. ID No. 5895 Seq. ID No. 5896 2804 Seq. ID No. 5897 Seq. ID No. 5898 2805b Seq. ID No. 5901 Seq. ID No. 5902 2809 Seq. ID No. 5903 Seq. ID No. 5904 2810d Seq. ID No. 5911 Seq. ID No. 5912 2812 Seq. ID No. 5913 Seq. ID No. 5914 2814 Seq. ID No. 5915 Seq. ID No. 5916 2815 Seq. ID No. 5917 Seq. ID No. 5918 2816 Seq. ID No. 5919 Seq. ID No. 5920 2818e Seq. ID No. 5929 Seq. ID No. 5930 2819 Seq. ID No. 5931 Seq. ID No. 5932 2820 Seq. ID No. 5933 Seq. ID No. 5934 2821b Seq. ID No. 5937 Seq. ID No. 5938 2822b Seq. ID No. 5941 Seq. ID No. 5942 2823 Seq. ID No. 5943 Seq. ID No. 5944 2824b Seq. ID No. 5947 Seq. ID No. 5948 2829b Seq. ID No. 5951 Seq. ID No. 5952 2831b Seq. ID No. 5953 Seq. ID No. 5954 2832 Seq. ID No. 5955 Seq. ID No. 5956 2833 Seq. ID No. 5957 Seq. ID No. 5958 2834b Seq. ID No. 5961 Seq. ID No. 5962 2842b Seq. ID No. 5969 Seq. ID No. 5970 2843b Seq. ID No. 5973 Seq. ID No. 5974 2846b Seq. ID No. 5979 Seq. ID No. 5980 2848 Seq. ID No. 5981 Seq. ID No. 5982 2851 Seq. ID No. 5985 Seq. ID No. 5986 2853 Seq. ID No. 5989 Seq. ID No. 5990 2854b Seq. ID No. 5993 Seq. ID No. 5994 2856c Seq. ID No. 6001 Seq. ID No. 6002 2857 Seq. ID No. 6003 Seq. ID No. 6004 2860c Seq. ID No. 6011 Seq. ID No. 6012 2863 Seq. ID No. 6015 Seq. ID No. 6016 2864 Seq. ID No. 6017 Seq. ID No. 6018 2868b Seq. ID No. 6021 Seq. ID No. 6022 2869c Seq. ID No. 6027 Seq. ID No. 6028 2871 Seq. ID No. 6029 Seq. ID No. 6030 2875 Seq. ID No. 6033 Seq. ID No. 6034 2877 Seq. ID No. 6035 Seq. ID No. 6036 2879c Seq. ID No. 6041 Seq. ID No. 6042 2881 Seq. ID No. 6043 Seq. ID No. 6044 2883d Seq. ID No. 6053 Seq. ID No. 6054 2886b Seq. ID No. 6057 Seq. ID No. 6058 2890 Seq. ID No. 6065 Seq. ID No. 6066 2891c Seq. ID No. 6071 Seq. ID No. 6072 2894c Seq. ID No. 6079 Seq. ID No. 6080 2897b Seq. ID No. 6085 Seq. ID No. 6086 2900b Seq. ID No. 6089 Seq. ID No. 6090 2902 Seq. ID No. 6095 Seq. ID No. 6096 2904 Seq. ID No. 6097 Seq. ID No. 6098 2905b Seq. ID No. 6101 Seq. ID No. 6102 2906 Seq. ID No. 6103 Seq. ID No. 6104 2909d Seq. ID No. 6111 Seq. ID No. 6112 2912 Seq. ID No. 6113 Seq. ID No. 6114 2913b Seq. ID No. 6117 Seq. ID No. 6118 2915c Seq. ID No. 6123 Seq. ID No. 6124 2916 Seq. ID No. 6125 Seq. ID No. 6126 2918 Seq. ID No. 6129 Seq. ID No. 6130 2920 Seq. ID No. 6131 Seq. ID No. 6132 2921 Seq. ID No. 6133 Seq. ID No. 6134 2923c Seq. ID No. 6141 Seq. ID No. 6142 2925b Seq. ID No. 6145 Seq. ID No. 6146 2926b Seq. ID No. 6149 Seq. ID No. 6150 2928c Seq. ID No. 6157 Seq. ID No. 6158 2931c Seq. ID No. 6165 Seq. ID No. 6166 2933b Seq. ID No. 6169 Seq. ID No. 6170 2934 Seq. ID No. 6171 Seq. ID No. 6172 2935b Seq. ID No. 6175 Seq. ID No. 6176 2936 Seq. ID No. 6177 Seq. ID No. 6178 2939b Seq. ID No. 6181 Seq. ID No. 6182 2941c Seq. ID No. 6187 Seq. ID No. 6188 2943d Seq. ID No. 6195 Seq. ID No. 6196 2947 Seq. ID No. 6201 Seq. ID No. 6202 2948d Seq. ID No. 6209 Seq. ID No. 6210 2950b Seq. ID No. 6213 Seq. ID No. 6214 2951 Seq. ID No. 6215 Seq. ID No. 6216 2954 Seq. ID No. 6219 Seq. ID No. 6220 2955g Seq. ID No. 6233 Seq. ID No. 6234 2957 Seq. ID No. 6235 Seq. ID No. 6236 2959 Seq. ID No. 6243 Seq. ID No. 6244 2962b Seq. ID No. 6249 Seq. ID No. 6250 2963 Seq. ID No. 6251 Seq. ID No. 6252 2965c Seq. ID No. 6257 Seq. ID No. 6258 2967 Seq. ID No. 6261 Seq. ID No. 6262 2969 Seq. ID No. 6263 Seq. ID No. 6264 2971b Seq. ID No. 6271 Seq. ID No. 6272 2974b Seq. ID No. 6275 Seq. ID No. 6276 2975 Seq. ID No. 6277 Seq. ID No. 6278 2977b Seq. ID No. 6281 Seq. ID No. 6282 2979 Seq. ID No. 6287 Seq. ID No. 6288 2980e Seq. ID No. 6297 Seq. ID No. 6298 2984 Seq. ID No. 6299 Seq. ID No. 6300 2986c Seq. ID No. 6305 Seq. ID No. 6306 2988c Seq. ID No. 6311 Seq. ID No. 6312 2990 Seq. ID No. 6315 Seq. ID No. 6316 2991c Seq. ID No. 6321 Seq. ID No. 6322 2992 Seq. ID No. 6323 Seq. ID No. 6324 2993b Seq. ID No. 6327 Seq. ID No. 6328 2995b Seq. ID No. 6331 Seq. ID No. 6332 2997 Seq. ID No. 6333 Seq. ID No. 6334 2998b Seq. ID No. 6337 Seq. ID No. 6338 2999 Seq. ID No. 6339 Seq. ID No. 6340 3001 Seq. ID No. 6341 Seq. ID No. 6342 3003 Seq. ID No. 6343 Seq. ID No. 6344 3005 Seq. ID No. 6345 Seq. ID No. 6346 3008d Seq. ID No. 6353 Seq. ID No. 6354 3010b Seq. ID No. 6357 Seq. ID No. 6358 3012 Seq. ID No. 6359 Seq. ID No. 6360 3015 Seq. ID No. 6361 Seq. ID No. 6362 3016c Seq. ID No. 6367 Seq. ID No. 6368 3017 Seq. ID No. 6369 Seq. ID No. 6370 3018b Seq. ID No. 6373 Seq. ID No. 6374 3020 Seq. ID No. 6375 Seq. ID No. 6376 3021 Seq. ID No. 6377 Seq. ID No. 6378 3022 Seq. ID No. 6379 Seq. ID No. 6380 3026b Seq. ID No. 6389 Seq. ID No. 6390 3028c Seq. ID No. 6395 Seq. ID No. 6396 3029b Seq. ID No. 6399 Seq. ID No. 6400 3031b Seq. ID No. 6403 Seq. ID No. 6404 3032b Seq. ID No. 6407 Seq. ID No. 6408 3033b Seq. ID No. 6411 Seq. ID No. 6412 3035 Seq. ID No. 6413 Seq. ID No. 6414 3037b Seq. ID No. 6417 Seq. ID No. 6418 3040b Seq. ID No. 6423 Seq. ID No. 6424 3044 Seq. ID No. 6433 Seq. ID No. 6434 3045b Seq. ID No. 6437 Seq. ID No. 6438 3048a Seq. ID No. 6439 Seq. ID No. 6440 3049c Seq. ID No. 6445 Seq. ID No. 6446 3051b Seq. ID No. 6449 Seq. ID No. 6450 3052 Seq. ID No. 6451 Seq. ID No. 6452 3055b Seq. ID No. 6457 Seq. ID No. 6458 3057 Seq. ID No. 6459 Seq. ID No. 6460 3059 Seq. ID No. 6461 Seq. ID No. 6462 3060 Seq. ID No. 6463 Seq. ID No. 6464 3065b Seq. ID No. 6477 Seq. ID No. 6478 3067 Seq. ID No. 6481 Seq. ID No. 6482 3068 Seq. ID No. 6483 Seq. ID No. 6484 3071 Seq. ID No. 6487 Seq. ID No. 6488 3072a Seq. ID No. 6489 Seq. ID No. 6490 3073 Seq. ID No. 6491 Seq. ID No. 6492 3074 Seq. ID No. 6493 Seq. ID No. 6494 3075 Seq. ID No. 6495 Seq. ID No. 6496 3077c Seq. ID No. 6503 Seq. ID No. 6504 3078 Seq. ID No. 6505 Seq. ID No. 6506 3081b Seq. ID No. 6511 Seq. ID No. 6512 3083d Seq. ID No. 6515 Seq. ID No. 6516 3086 Seq. ID No. 6519 Seq. ID No. 6520 3087c Seq. ID No. 6523 Seq. ID No. 6524 3088 Seq. ID No. 6525 Seq. ID No. 6526 3089b Seq. ID No. 6529 Seq. ID No. 6530 3090 Seq. ID No. 6531 Seq. ID No. 6532 3091 Seq. ID No. 6533 Seq. ID No. 6534 3092b Seq. ID No. 6537 Seq. ID No. 6538 3097 Seq. ID No. 6545 Seq. ID No. 6546 3098c Seq. ID No. 6551 Seq. ID No. 6552 3099 Seq. ID No. 6553 Seq. ID No. 6554 3101 Seq. ID No. 6559 Seq. ID No. 6560 3103b Seq. ID No. 6563 Seq. ID No. 6564 3105 Seq. ID No. 6567 Seq. ID No. 6568 3108b Seq. ID No. 6577 Seq. ID No. 6578 3109 Seq. ID No. 6579 Seq. ID No. 6580 3110b Seq. ID No. 6583 Seq. ID No. 6584 3113 Seq. ID No. 6585 Seq. ID No. 6586 3116 Seq. ID No. 6587 Seq. ID No. 6588 3118a Seq. ID No. 6589 Seq. ID No. 6590 3119f Seq. ID No. 6603 Seq. ID No. 6604 3121 Seq. ID No. 6605 Seq. ID No. 6606 3122b Seq. ID No. 6609 Seq. ID No. 6610 3123b Seq. ID No. 6613 Seq. ID No. 6614 3124 Seq. ID No. 6615 Seq. ID No. 6616 3126 Seq. ID No. 6617 Seq. ID No. 6618 3129b Seq. ID No. 6621 Seq. ID No. 6622 3131 Seq. ID No. 6623 Seq. ID No. 6624 3134b Seq. ID No. 6627 Seq. ID No. 6628 3138 Seq. ID No. 6629 Seq. ID No. 6630 3141 Seq. ID No. 6633 Seq. ID No. 6634 3145c Seq. ID No. 6639 Seq. ID No. 6640

Listed in Table 19 are the 1534 ORFs detected by the GeneMark™ ORF finder program trained on Bacillus subtilis published ORFs. TABLE 19 GENEMARK ™ ORFs ORF Number DNA SEQ ID Number Protein SEQ ID Number 1 Seq. ID No. 1 Seq. ID No. 2 2a Seq. ID No. 3 Seq. ID No. 4 4c Seq. ID No. 11 Seq. ID No. 12 5 Seq. ID No. 13 Seq. ID No. 14 7 Seq. ID No. 15 Seq. ID No. 16 10 Seq. ID No. 17 Seq. ID No. 18 17 Seq. ID No. 25 Seq. ID No. 26 18 Seq. ID No. 27 Seq. ID No. 28 20 Seq. ID No. 29 Seq. ID No. 30 23b Seq. ID No. 35 Seq. ID No. 36 24 Seq. ID No. 37 Seq. ID No. 38 32 Seq. ID No. 39 Seq. ID No. 40 36 Seq. ID No. 41 Seq. ID No. 42 37 Seq. ID No. 43 Seq. ID No. 44 38a Seq. ID No. 45 Seq. ID No. 46 39a Seq. ID No. 49 Seq. ID No. 50 40 Seq. ID No. 53 Seq. ID No. 54 41b Seq. ID No. 57 Seq. ID No. 58 43b Seq. ID No. 61 Seq. ID No. 62 45 Seq. ID No. 69 Seq. ID No. 70 46a Seq. ID No. 71 Seq. ID No. 72 47 Seq. ID No. 75 Seq. ID No. 76 48c Seq. ID No. 81 Seq. ID No. 82 50 Seq. ID No. 83 Seq. ID No. 84 51c Seq. ID No. 89 Seq. ID No. 90 57a Seq. ID No. 95 Seq. ID No. 96 60a Seq. ID No. 101 Seq. ID No. 102 62c Seq. ID No. 111 Seq. ID No. 112 65b Seq. ID No. 119 Seq. ID No. 120 67 Seq. ID No. 125 Seq. ID No. 126 71 Seq. ID No. 129 Seq. ID No. 130 74 Seq. ID No. 135 Seq. ID No. 136 77 Seq. ID No. 137 Seq. ID No. 138 80a Seq. ID No. 141 Seq. ID No. 142 81a Seq. ID No. 147 Seq. ID No. 148 83 Seq. ID No. 151 Seq. ID No. 152 85b Seq. ID No. 155 Seq. ID No. 156 88 Seq. ID No. 167 Seq. ID No. 168 91a Seq. ID No. 171 Seq. ID No. 172 93b Seq. ID No. 181 Seq. ID No. 182 94 Seq. ID No. 185 Seq. ID No. 186 95b Seq. ID No. 187 Seq. ID No. 188 97b Seq. ID No. 189 Seq. ID No. 190 99 Seq. ID No. 191 Seq. ID No. 192 102 Seq. ID No. 195 Seq. ID No. 196 104b Seq. ID No. 199 Seq. ID No. 200 106 Seq. ID No. 207 Seq. ID No. 208 109c Seq. ID No. 213 Seq. ID No. 214 111b Seq. ID No. 219 Seq. ID No. 220 112a Seq. ID No. 221 Seq. ID No. 222 114 Seq. ID No. 225 Seq. ID No. 226 115 Seq. ID No. 227 Seq. ID No. 228 119a Seq. ID No. 229 Seq. ID No. 230 121 Seq. ID No. 233 Seq. ID No. 234 124c Seq. ID No. 239 Seq. ID No. 240 125 Seq. ID No. 241 Seq. ID No. 242 127a Seq. ID No. 243 Seq. ID No. 244 129c Seq. ID No. 253 Seq. ID No. 254 134 Seq. ID No. 261 Seq. ID No. 262 135a Seq. ID No. 263 Seq. ID No. 264 137a Seq. ID No. 267 Seq. ID No. 268 138b Seq. ID No. 273 Seq. ID No. 274 142 Seq. ID No. 275 Seq. ID No. 276 143 Seq. ID No. 277 Seq. ID No. 278 144a Seq. ID No. 279 Seq. ID No. 280 145d Seq. ID No. 291 Seq. ID No. 292 147 Seq. ID No. 293 Seq. ID No. 294 151a Seq. ID No. 295 Seq. ID No. 296 152a Seq. ID No. 299 Seq. ID No. 300 153a Seq. ID No. 303 Seq. ID No. 304 154 Seq. ID No. 309 Seq. ID No. 310 155a Seq. ID No. 311 Seq. ID No. 312 157a Seq. ID No. 315 Seq. ID No. 316 158a Seq. ID No. 319 Seq. ID No. 320 160a Seq. ID No. 323 Seq. ID No. 324 162c Seq. ID No. 331 Seq. ID No. 332 165a Seq. ID No. 341 Seq. ID No. 342 167 Seq. ID No. 345 Seq. ID No. 346 171a Seq. ID No. 351 Seq. ID No. 352 172 Seq. ID No. 355 Seq. ID No. 356 175 Seq. ID No. 361 Seq. ID No. 362 176 Seq. ID No. 363 Seq. ID No. 364 177a Seq. ID No. 365 Seq. ID No. 366 180b Seq. ID No. 375 Seq. ID No. 376 184 Seq. ID No. 379 Seq. ID No. 380 185 Seq. ID No. 381 Seq. ID No. 382 186 Seq. ID No. 383 Seq. ID No. 384 188 Seq. ID No. 389 Seq. ID No. 390 189b Seq. ID No. 391 Seq. ID No. 392 192a Seq. ID No. 395 Seq. ID No. 396 193 Seq. ID No. 399 Seq. ID No. 400 195 Seq. ID No. 405 Seq. ID No. 406 197a Seq. ID No. 409 Seq. ID No. 410 198a Seq. ID No. 413 Seq. ID No. 414 200 Seq. ID No. 417 Seq. ID No. 418 202 Seq. ID No. 421 Seq. ID No. 422 203 Seq. ID No. 423 Seq. ID No. 424 204 Seq. ID No. 425 Seq. ID No. 426 205 Seq. ID No. 427 Seq. ID No. 428 206 Seq. ID No. 429 Seq. ID No. 430 208b Seq. ID No. 435 Seq. ID No. 436 210 Seq. ID No. 437 Seq. ID No. 438 211 Seq. ID No. 439 Seq. ID No. 440 213 Seq. ID No. 441 Seq. ID No. 442 215a Seq. ID No. 443 Seq. ID No. 444 218 Seq. ID No. 445 Seq. ID No. 446 219 Seq. ID No. 447 Seq. ID No. 448 220a Seq. ID No. 449 Seq. ID No. 450 226a Seq. ID No. 459 Seq. ID No. 460 228a Seq. ID No. 465 Seq. ID No. 466 236c Seq. ID No. 485 Seq. ID No. 486 245c Seq. ID No. 501 Seq. ID No. 502 246b Seq. ID No. 505 Seq. ID No. 506 248b Seq. ID No. 511 Seq. ID No. 512 249a Seq. ID No. 513 Seq. ID No. 514 251 Seq. ID No. 517 Seq. ID No. 518 253a Seq. ID No. 519 Seq. ID No. 520 254 Seq. ID No. 523 Seq. ID No. 524 255c Seq. ID No. 529 Seq. ID No. 530 258 Seq. ID No. 533 Seq. ID No. 534 259a Seq. ID No. 535 Seq. ID No. 536 260 Seq. ID No. 541 Seq. ID No. 542 262 Seq. ID No. 543 Seq. ID No. 544 265 Seq. ID No. 551 Seq. ID No. 552 267b Seq. ID No. 553 Seq. ID No. 554 269a Seq. ID No. 559 Seq. ID No. 560 271a Seq. ID No. 563 Seq. ID No. 564 273b Seq. ID No. 569 Seq. ID No. 570 277c Seq. ID No. 575 Seq. ID No. 576 279b Seq. ID No. 579 Seq. ID No. 580 280b Seq. ID No. 583 Seq. ID No. 584 283a Seq. ID No. 591 Seq. ID No. 592 284a Seq. ID No. 595 Seq. ID No. 596 286a Seq. ID No. 601 Seq. ID No. 602 287 Seq. ID No. 605 Seq. ID No. 606 290a Seq. ID No. 607 Seq. ID No. 608 293 Seq. ID No. 611 Seq. ID No. 612 294 Seq. ID No. 613 Seq. ID No. 614 296 Seq. ID No. 615 Seq. ID No. 616 301a Seq. ID No. 621 Seq. ID No. 622 304b Seq. ID No. 627 Seq. ID No. 628 307 Seq. ID No. 629 Seq. ID No. 630 309 Seq. ID No. 633 Seq. ID No. 634 310 Seq. ID No. 635 Seq. ID No. 636 311 Seq. ID No. 637 Seq. ID No. 638 313c Seq. ID No. 643 Seq. ID No. 644 315 Seq. ID No. 649 Seq. ID No. 650 316a Seq. ID No. 651 Seq. ID No. 652 317b Seq. ID No. 655 Seq. ID No. 656 318a Seq. ID No. 657 Seq. ID No. 658 321 Seq. ID No. 669 Seq. ID No. 670 323a Seq. ID No. 671 Seq. ID No. 672 324 Seq. ID No. 675 Seq. ID No. 676 327c Seq. ID No. 681 Seq. ID No. 682 329 Seq. ID No. 683 Seq. ID No. 684 330a Seq. ID No. 685 Seq. ID No. 686 332 Seq. ID No. 693 Seq. ID No. 694 337 Seq. ID No. 703 Seq. ID No. 704 338a Seq. ID No. 705 Seq. ID No. 706 341a Seq. ID No. 711 Seq. ID No. 712 342f Seq. ID No. 725 Seq. ID No. 726 344a Seq. ID No. 731 Seq. ID No. 732 345 Seq. ID No. 735 Seq. ID No. 736 346a Seq. ID No. 737 Seq. ID No. 738 347 Seq. ID No. 741 Seq. ID No. 742 349a Seq. ID No. 743 Seq. ID No. 744 350a Seq. ID No. 749 Seq. ID No. 750 351 Seq. ID No. 753 Seq. ID No. 754 352c Seq. ID No. 759 Seq. ID No. 760 356c Seq. ID No. 773 Seq. ID No. 774 358c Seq. ID No. 781 Seq. ID No. 782 362 Seq. ID No. 783 Seq. ID No. 784 365a Seq. ID No. 785 Seq. ID No. 786 366b Seq. ID No. 789 Seq. ID No. 790 367a Seq. ID No. 793 Seq. ID No. 794 371a Seq. ID No. 797 Seq. ID NO. 798 372b Seq. ID No. 803 Seq. ID No. 804 378a Seq. ID No. 815 Seq. ID No. 816 382b Seq. ID No. 819 Seq. ID No. 820 383a Seq. ID No. 821 Seq. ID No. 822 384b Seq. ID No. 827 Seq. ID No. 828 385b Seq. ID No. 831 Seq. ID No. 832 386 Seq. ID No. 833 Seq. ID No. 834 387 Seq. ID No. 835 Seq. ID No. 836 390 Seq. ID No. 837 Seq. ID No. 838 393b Seq. ID No. 841 Seq. ID No. 842 395a Seq. ID No. 843 Seq. ID No. 844 396 Seq. ID No. 849 Seq. ID No. 850 398 Seq. ID No. 851 Seq. ID No. 852 400a Seq. ID No. 853 Seq. ID No. 854 401a Seq. ID No. 857 Seq. ID No. 858 403c Seq. ID No. 865 Seq. ID No. 866 406a Seq. ID No. 869 Seq. ID No. 870 409a Seq. ID No. 873 Seq. ID No. 874 410a Seq. ID No. 877 Seq. ID No. 878 413a Seq. ID No. 883 Seq. ID No. 884 416a Seq. ID No. 887 Seq. ID No. 888 417 Seq. ID No. 891 Seq. ID No. 892 418b Seq. ID No. 895 Seq. ID No. 896 419c Seq. ID No. 901 Seq. ID No. 902 421 Seq. ID No. 907 Seq. ID No. 908 424a Seq. ID No. 911 Seq. ID No. 912 426a Seq. ID No. 917 Seq. ID No. 918 427a Seq. ID No. 921 Seq. ID No. 922 429a Seq. ID No. 927 Seq. ID No. 928 431 Seq. ID No. 935 Seq. ID No. 936 435 Seq. ID No. 939 Seq. ID No. 940 438a Seq. ID No. 945 Seq. ID No. 946 440 Seq. ID No. 951 Seq. ID No. 952 441a Seq. ID No. 953 Seq. ID No. 954 444a Seq. ID No. 959 Seq. ID No. 960 445a Seq. ID No. 963 Seq. ID No. 964 448 Seq. ID No. 967 Seq. ID No. 968 450a Seq. ID No. 969 Seq. ID No. 970 452a Seq. ID No. 977 Seq. ID No. 978 455a Seq. ID No. 989 Seq. ID No. 990 458a Seq. ID No. 995 Seq. ID No. 996 460a Seq. ID No. 999 Seq. ID No. 1000 462 Seq. ID No. 1005 Seq. ID No. 1006 463a Seq. ID No. 1007 Seq. ID No. 1008 464c Seq. ID No. 1015 Seq. ID No. 1016 467a Seq. ID No. 1021 Seq. ID No. 1022 472d Seq. ID No. 1035 Seq. ID No. 1036 473 Seq. ID No. 1041 Seq. ID No. 1042 474 Seq. ID No. 1043 Seq. ID No. 1044 478a Seq. ID No. 1049 Seq. ID No. 1050 479 Seq. ID No. 1053 Seq. ID No. 1054 480b Seq. ID No. 1057 Seq. ID No. 1058 481a Seq. ID No. 1059 Seq. ID No. 1060 482a Seq. ID No. 1063 Seq. ID No. 1064 483 Seq. ID No. 1067 Seq. ID No. 1068 490 Seq. ID No. 1069 Seq. ID No. 1070 491a Seq. ID No. 1071 Seq. ID No. 1072 492 Seq. ID No. 1075 Seq. ID No. 1076 495c Seq. ID No. 1083 Seq. ID No. 1084 498a Seq. ID No. 1085 Seq. ID No. 1086 499a Seq. ID No. 1089 Seq. ID No. 1090 500 Seq. ID No. 1093 Seq. ID No. 1094 502c Seq. ID No. 1097 Seq. ID No. 1098 504 Seq. ID No. 1099 Seq. ID No. 1100 505a Seq. ID No. 1101 Seq. ID No. 1102 509 Seq. ID No. 1109 Seq. ID No. 1110 512a Seq. ID No. 1113 Seq. ID No. 1114 514 Seq. ID No. 1117 Seq. ID No. 1118 515b Seq. ID No. 1121 Seq. ID No. 1122 518c Seq. ID No. 1129 Seq. ID No. 1130 523 Seq. ID No. 1133 Seq. ID No. 1134 524b Seq. ID No. 1137 Seq. ID No. 1138 527a Seq. ID No. 1141 Seq. ID No. 1142 528a Seq. ID No. 1145 Seq. ID No. 1146 529 Seq. ID No. 1149 Seq. ID No. 1150 533 Seq. ID No. 1155 Seq. ID No. 1156 535 Seq. ID No. 1157 Seq. ID No. 1158 536 Seq. ID No. 1159 Seq. ID No. 1160 539c Seq. ID No. 1163 Seq. ID No. 1164 541d Seq. ID No. 1171 Seq. ID No. 1172 542 Seq. ID No. 1173 Seq. ID No. 1174 543a Seq. ID No. 1175 Seq. ID No. 1176 544 Seq. ID No. 1181 Seq. ID No. 1182 545b Seq. ID No. 1185 Seq. ID No. 1186 546a Seq. ID No. 1189 Seq. ID No. 1190 548 Seq. ID No. 1199 Seq. ID No. 1200 551 Seq. ID No. 1205 Seq. ID No. 1206 554a Seq. ID No. 1209 Seq. ID No. 1210 557a Seq. ID No. 1215 Seq. ID No. 1216 560a Seq. ID No. 1219 Seq. 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ID No. 4546 2174 Seq. ID No. 4549 Seq. ID No. 4550 2176c Seq. ID No. 4557 Seq. ID No. 4558 2179a Seq. ID No. 4563 Seq. ID No. 4564 2180 Seq. ID No. 4567 Seq. ID No. 4568 2181a Seq. ID No. 4569 Seq. ID No. 4570 2183 Seq. ID No. 4575 Seq. ID No. 4576 2185 Seq. ID No. 4577 Seq. ID No. 4578 2186a Seq. ID No. 4579 Seq. ID No. 4580 2189a Seq. ID No. 4583 Seq. ID No. 4584 2193 Seq. ID No. 4591 Seq. ID No. 4592 2194a Seq. ID No. 4593 Seq. ID No. 4594 2196 Seq. ID No. 4597 Seq. ID No. 4598 2197b Seq. ID No. 4601 Seq. ID No. 4602 2201a Seq. ID No. 4605 Seq. ID No. 4606 2203 Seq. ID No. 4609 Seq. ID No. 4610 2204 Seq. ID No. 4611 Seq. ID No. 4612 2206a Seq. ID No. 4613 Seq. ID No. 4614 2209 Seq. ID No. 4623 Seq. ID No. 4624 2212a Seq. ID No. 4625 Seq. ID No. 4626 2215a Seq. ID No. 4629 Seq. ID No. 4630 2216a Seq. ID No. 4633 Seq. ID No. 4634 2218 Seq. ID No. 4637 Seq. ID No. 4638 2219b Seq. ID No. 4641 Seq. ID No. 4642 2220a Seq. ID No. 4645 Seq. ID No. 4646 2221 Seq. ID No. 4651 Seq. ID No. 4652 2222 Seq. ID No. 4653 Seq. ID No. 4654 2223a Seq. ID No. 4655 Seq. ID No. 4656 2226 Seq. ID No. 4661 Seq. ID No. 4662 2227 Seq. ID No. 4663 Seq. ID No. 4664 2228c Seq. ID No. 4669 Seq. ID No. 4670 2231 Seq. ID No. 4671 Seq. ID No. 4672 2232 Seq. ID No. 4673 Seq. ID No. 4674 2234a Seq. ID No. 4675 Seq. ID No. 4676 2238 Seq. ID No. 4685 Seq. ID No. 4686 2240a Seq. ID No. 4689 Seq. ID No. 4690 2244 Seq. ID No. 4697 Seq. ID No. 4698 2248 Seq. ID No. 4703 Seq. ID No. 4704 2249 Seq. ID No. 4705 Seq. ID No. 4706 2253d Seq. ID No. 4713 Seq. ID No. 4714 2255b Seq. ID No. 4717 Seq. ID No. 4718 2256 Seq. ID No. 4719 Seq. ID No. 4720 2259a Seq. ID No. 4723 Seq. ID No. 4724 2260c Seq. ID No. 4729 Seq. ID No. 4730 2262 Seq. ID No. 4731 Seq. ID No. 4732 2263 Seq. ID No. 4733 Seq. ID No. 4734 2267 Seq. ID No. 4739 Seq. ID No. 4740 2269 Seq. ID No. 4743 Seq. ID No. 4744 2270 Seq. ID No. 4745 Seq. ID No. 4746 2272 Seq. ID No. 4747 Seq. ID No. 4748 2273 Seq. ID No. 4749 Seq. ID No. 4750 2274 Seq. ID No. 4751 Seq. ID No. 4752 2275a Seq. ID No. 4753 Seq. ID No. 4754 2276b Seq. ID No. 4761 Seq. ID No. 4762 2277a Seq. ID No. 4767 Seq. ID No. 4768 2278a Seq. ID No. 4771 Seq. ID No. 4772 2280 Seq. ID No. 4779 Seq. ID No. 4780 2284 Seq. ID No. 4781 Seq. ID No. 4782 2285 Seq. ID No. 4783 Seq. ID No. 4784 2286a Seq. ID No. 4785 Seq. ID No. 4786 2288 Seq. ID No. 4789 Seq. ID No. 4790 2290 Seq. ID No. 4791 Seq. ID No. 4792 2291a Seq. ID No. 4793 Seq. ID No. 4794 2292a Seq. ID No. 4799 Seq. ID No. 4800 2297 Seq. ID No. 4807 Seq. ID No. 4808 2298 Seq. ID No. 4809 Seq. ID No. 4810 2299 Seq. ID No. 4811 Seq. ID No. 4812 2300 Seq. ID No. 4813 Seq. ID No. 4814 2301 Seq. ID No. 4815 Seq. ID No. 4816 2304 Seq. ID No. 4821 Seq. ID No. 4822 2307 Seq. ID No. 4825 Seq. ID No. 4826 2308 Seq. ID No. 4827 Seq. ID No. 4828 2309a Seq. ID No. 4829 Seq. ID No. 4830 2311 Seq. ID No. 4837 Seq. ID No. 4838 2312a Seq. ID No. 4839 Seq. ID No. 4840 2314 Seq. ID No. 4845 Seq. ID No. 4846 2315 Seq. ID No. 4847 Seq. ID No. 4848 2316 Seq. ID No. 4849 Seq. ID No. 4850 2321b Seq. ID No. 4857 Seq. ID No. 4858 2322 Seq. ID No. 4861 Seq. ID No. 4862 2327 Seq. ID No. 4865 Seq. ID No. 4866 2328 Seq. ID No. 4867 Seq. ID No. 4868 2329d Seq. ID No. 4875 Seq. ID No. 4876 2331 Seq. ID No. 4879 Seq. ID No. 4880 2333 Seq. ID No. 4881 Seq. ID No. 4882 2335 Seq. ID No. 4883 Seq. ID No. 4884 2336 Seq. ID No. 4885 Seq. ID No. 4886 2337b Seq. ID No. 4887 Seq. ID No. 4888 2338c Seq. ID No. 4893 Seq. ID No. 4894 2342c Seq. ID No. 4899 Seq. ID No. 4900 2344 Seq. ID No. 4901 Seq. ID No. 4902 2345 Seq. ID No. 4903 Seq. ID No. 4904 2347 Seq. ID No. 4905 Seq. ID No. 4906 2348 Seq. ID No. 4907 Seq. ID No. 4908 2349a Seq. ID No. 4909 Seq. ID No. 4910 2353 Seq. ID No. 4915 Seq. ID No. 4916 2354 Seq. ID No. 4917 Seq. ID No. 4918 2357 Seq. ID No. 4919 Seq. ID No. 4920 2358 Seq. ID No. 4921 Seq. ID No. 4922 2361a Seq. ID No. 4925 Seq. ID No. 4926 2363a Seq. ID No. 4929 Seq. ID No. 4930 2365a Seq. ID No. 4933 Seq. ID No. 4934 2366a Seq. ID No. 4937 Seq. ID No. 4938 2367 Seq. ID No. 4941 Seq. ID No. 4942 2368 Seq. ID No. 4943 Seq. ID No. 4944 2369 Seq. ID No. 4945 Seq. ID No. 4946 2370 Seq. ID No. 4947 Seq. ID No. 4948 2373 Seq. ID No. 4953 Seq. ID No. 4954 2374a Seq. ID No. 4955 Seq. ID No. 4956 2376 Seq. ID No. 4959 Seq. ID No. 4960 2377a Seq. ID No. 4961 Seq. ID No. 4962 2378 Seq. ID No. 4965 Seq. ID No. 4966 2379a Seq. ID No. 4967 Seq. ID No. 4968 2380 Seq. ID No. 4971 Seq. ID No. 4972 2381 Seq. ID No. 4973 Seq. ID No. 4974 2384a Seq. ID No. 4977 Seq. ID No. 4978 2387 Seq. ID No. 4985 Seq. ID No. 4986 2391 Seq. ID No. 4989 Seq. ID No. 4990 2392 Seq. ID No. 4991 Seq. ID No. 4992 2395 Seq. ID No. 4995 Seq. ID No. 4996 2396 Seq. ID No. 4997 Seq. ID No. 4998 2399b Seq. ID No. 5005 Seq. ID No. 5006 2401 Seq. ID No. 5009 Seq. ID No. 5010 2403a Seq. ID No. 5015 Seq. ID No. 5016 2404a Seq. ID No. 5019 Seq. ID No. 5020 2409a Seq. ID No. 5025 Seq. ID No. 5026 2410 Seq. ID No. 5029 Seq. ID No. 5030 2415a Seq. ID No. 5037 Seq. ID No. 5038 2417a Seq. ID No. 5045 Seq. ID No. 5046 2418a Seq. ID No. 5049 Seq. ID No. 5050 2420 Seq. ID No. 5053 Seq. ID No. 5054 2421 Seq. ID No. 5055 Seq. ID No. 5056 2422c Seq. ID No. 5059 Seq. ID No. 5060 2423a Seq. ID No. 5061 Seq. ID No. 5062 2424a Seq. ID No. 5065 Seq. ID No. 5066 2426 Seq. ID No. 5071 Seq. ID No. 5072 2428a Seq. ID No. 5073 Seq. ID No. 5074 2429 Seq. ID No. 5079 Seq. ID No. 5080 2432 Seq. ID No. 5081 Seq. ID No. 5082 2433 Seq. ID No. 5083 Seq. ID No. 5084 2440 Seq. ID No. 5087 Seq. ID No. 5088 2442a Seq. ID No. 5089 Seq. ID No. 5090 2443 Seq. ID No. 5093 Seq. ID No. 5094 2444a Seq. ID No. 5095 Seq. ID No. 5096 2445 Seq. ID No. 5103 Seq. ID No. 5104 2448b Seq. ID No. 5105 Seq. ID No. 5106 2449a Seq. ID No. 5107 Seq. ID No. 5108 2451 Seq. ID No. 5111 Seq. ID No. 5112 2452 Seq. ID No. 5113 Seq. ID No. 5114 2453 Seq. ID No. 5115 Seq. ID No. 5116 2455 Seq. ID No. 5117 Seq. ID No. 5118 2456a Seq. ID No. 5119 Seq. ID No. 5120 2458g Seq. ID No. 5141 Seq. ID No. 5142 2461a Seq. ID No. 5143 Seq. ID No. 5144 2462a Seq. ID No. 5147 Seq. ID No. 5148 2464 Seq. ID No. 5153 Seq. ID No. 5154 2465a Seq. ID No. 5155 Seq. ID No. 5156 2469a Seq. ID No. 5163 Seq. ID No. 5164 2471 Seq. ID No. 5169 Seq. ID No. 5170 2473 Seq. ID No. 5171 Seq. ID No. 5172 2474a Seq. ID No. 5173 Seq. ID No. 5174 2475a Seq. ID No. 5179 Seq. ID No. 5180 2477 Seq. ID No. 5185 Seq. ID No. 5186 2480 Seq. ID No. 5187 Seq. ID No. 5188 2482 Seq. ID No. 5193 Seq. ID No. 5194 2483 Seq. ID No. 5195 Seq. ID No. 5196 2485 Seq. ID No. 5201 Seq. ID No. 5202 2489 Seq. ID No. 5203 Seq. ID No. 5204 2490 Seq. ID No. 5205 Seq. ID No. 5206 2492b Seq. ID No. 5209 Seq. ID No. 5210 2494 Seq. ID No. 5211 Seq. ID No. 5212 2495a Seq. ID No. 5213 Seq. ID No. 5214 2497a Seq. ID No. 5217 Seq. ID No. 5218 2500b Seq. ID No. 5225 Seq. ID No. 5226 2501b Seq. ID No. 5231 Seq. ID No. 5232 2504a Seq. ID No. 5233 Seq. ID No. 5234 2505 Seq. ID No. 5237 Seq. ID No. 5238 2506 Seq. ID No. 5239 Seq. ID No. 5240 2510 Seq. ID No. 5245 Seq. ID No. 5246 2512c Seq. ID No. 5247 Seq. ID No. 5248 2513a Seq. ID No. 5249 Seq. ID No. 5250 2514 Seq. ID No. 5255 Seq. ID No. 5256 2515 Seq. ID No. 5257 Seq. ID No. 5258 2516a Seq. ID No. 5259 Seq. ID No. 5260 2517a Seq. ID No. 5263 Seq. ID No. 5264 2519a Seq. ID No. 5269 Seq. ID No. 5270 2520a Seq. ID No. 5273 Seq. ID No. 5274 2523 Seq. ID No. 5283 Seq. ID No. 5284 2527a Seq. ID No. 5289 Seq. ID No. 5290 2528a Seq. ID No. 5293 Seq. ID No. 5294 2535a Seq. ID No. 5307 Seq. ID No. 5308 2538 Seq. ID No. 5311 Seq. ID No. 5312 2541 Seq. ID No. 5313 Seq. ID No. 5314 2542a Seq. ID No. 5315 Seq. ID No. 5316 2544 Seq. ID No. 5323 Seq. ID No. 5324 2545 Seq. ID No. 5325 Seq. ID No. 5326 2548b Seq. ID No. 5335 Seq. ID No. 5336 2549 Seq. ID No. 5337 Seq. ID No. 5338 2550b Seq. ID No. 5339 Seq. ID No. 5340 2552 Seq. ID No. 5345 Seq. ID No. 5346 2553 Seq. ID No. 5347 Seq. ID No. 5348 2554a Seq. ID No. 5349 Seq. ID No. 5350 2555a Seq. ID No. 5353 Seq. ID No. 5354 2558a Seq. ID No. 5361 Seq. ID No. 5362 2559 Seq. ID No. 5365 Seq. ID No. 5366 2561 Seq. ID No. 5367 Seq. ID No. 5368 2562a Seq. ID No. 5369 Seq. ID No. 5370 2563 Seq. ID No. 5373 Seq. ID No. 5374 2564a Seq. ID No. 5375 Seq. ID No. 5376 2567b Seq. ID No. 5387 Seq. ID No. 5388 2568 Seq. ID No. 5389 Seq. ID No. 5390 2572 Seq. ID No. 5391 Seq. ID No. 5392 2573 Seq. ID No. 5393 Seq. ID No. 5394 2575 Seq. ID No. 5395 Seq. ID No. 5396 2576 Seq. ID No. 5397 Seq. ID No. 5398 2578 Seq. ID No. 5399 Seq. ID No. 5400 2579b Seq. ID No. 5401 Seq. ID No. 5402 2581 Seq. ID No. 5403 Seq. ID No. 5404 2582a Seq. ID No. 5405 Seq. ID No. 5406 2585 Seq. ID No. 5411 Seq. ID No. 5412 2587b Seq. ID No. 5415 Seq. ID No. 5416 2588 Seq. ID No. 5417 Seq. ID No. 5418 2589 Seq. ID No. 5419 Seq. ID No. 5420 2591 Seq. ID No. 5421 Seq. ID No. 5422 2592 Seq. ID No. 5423 Seq. ID No. 5424 2594a Seq. ID No. 5429 Seq. ID No. 5430 2596 Seq. ID No. 5433 Seq. ID No. 5434 2598 Seq. ID No. 5441 Seq. ID No. 5442 2602 Seq. ID No. 5443 Seq. ID No. 5444 2605a Seq. ID No. 5445 Seq. ID No. 5446 2606 Seq. ID No. 5449 Seq. ID No. 5450 2608 Seq. ID No. 5451 Seq. ID No. 5452 2610 Seq. ID No. 5453 Seq. ID No. 5454 2611 Seq. ID No. 5455 Seq. ID No. 5456 2613 Seq. ID No. 5457 Seq. ID No. 5458 2616f Seq. ID No. 5469 Seq. ID No. 5470 2617a Seq. ID No. 5475 Seq. ID No. 5476 2619 Seq. ID No. 5483 Seq. ID No. 5484 2620 Seq. ID No. 5485 Seq. ID No. 5486 2623a Seq. ID No. 5489 Seq. ID No. 5490 2624a Seq. ID No. 5493 Seq. ID No. 5494 2625b Seq. ID No. 5499 Seq. ID No. 5500 2626a Seq. ID No. 5501 Seq. ID No. 5502 2627a Seq. ID No. 5505 Seq. ID No. 5506 2628 Seq. ID No. 5509 Seq. ID No. 5510 2629a Seq. ID No. 5511 Seq. ID No. 5512 2633c Seq. ID No. 5523 Seq. ID No. 5524 2637a Seq. ID No. 5529 Seq. ID No. 5530 2643a Seq. ID No. 5535 Seq. ID No. 5536 2645 Seq. ID No. 5539 Seq. ID No. 5540 2647 Seq. ID No. 5541 Seq. ID No. 5542 2649 Seq. ID No. 5547 Seq. ID No. 5548 2652a Seq. ID No. 5551 Seq. ID No. 5552 2655a Seq. ID No. 5555 Seq. ID No. 5556 2656 Seq. ID No. 5559 Seq. ID No. 5560 2658a Seq. ID No. 5561 Seq. ID No. 5562 2659a Seq. ID No. 5565 Seq. ID No. 5566 2662 Seq. ID No. 5571 Seq. ID No. 5572 2664a Seq. ID No. 5573 Seq. ID No. 5574 2666a Seq. ID No. 5579 Seq. ID No. 5580 2667a Seq. ID No. 5583 Seq. ID No. 5584 2669b Seq. ID No. 5589 Seq. ID No. 5590 2674b Seq. ID No. 5599 Seq. ID No. 5600 2676 Seq. ID No. 5601 Seq. ID No. 5602 2677a Seq. ID No. 5603 Seq. ID No. 5604 2679c Seq. ID No. 5613 Seq. ID No. 5614 2680c Seq. ID No. 5621 Seq. ID No. 5622 2684a Seq. ID No. 5627 Seq. ID No. 5628 2686 Seq. ID No. 5631 Seq. ID No. 5632 2688b Seq. ID No. 5635 Seq. ID No. 5636 2690b Seq. ID No. 5645 Seq. ID No. 5646 2693 Seq. ID No. 5651 Seq. ID No. 5652 2694a Seq. ID No. 5653 Seq. ID No. 5654 2695 Seq. ID No. 5657 Seq. ID No. 5658 2696b Seq. ID No. 5661 Seq. ID No. 5662 2705 Seq. ID No. 5663 Seq. ID No. 5664 2709 Seq. ID No. 5665 Seq. ID No. 5666 2712 Seq. ID No. 5669 Seq. ID No. 5670 2713 Seq. ID No. 5671 Seq. ID No. 5672 2714 Seq. ID No. 5673 Seq. ID No. 5674 2716a Seq. ID No. 5675 Seq. ID No. 5676 2718a Seq. ID No. 5681 Seq. ID No. 5682 2721b Seq. ID No. 5693 Seq. ID No. 5694 2722a Seq. ID No. 5695 Seq. ID No. 5696 2723 Seq. ID No. 5699 Seq. ID No. 5700 2724 Seq. ID No. 5701 Seq. ID No. 5702 2726 Seq. ID No. 5707 Seq. ID No. 5708 2731a Seq. ID No. 5713 Seq. ID No. 5714 2732 Seq. ID No. 5717 Seq. ID No. 5718 2734c Seq. ID No. 5723 Seq. ID No. 5724 2735a Seq. ID No. 5725 Seq. ID No. 5726 2738b Seq. ID No. 5731 Seq. ID No. 5732 2742a Seq. ID No. 5737 Seq. ID No. 5738 2745a Seq. ID No. 5747 Seq. ID No. 5748 2746 Seq. ID No. 5751 Seq. ID No. 5752 2747b Seq. ID No. 5755 Seq. ID No. 5756 2748b Seq. ID No. 5759 Seq. ID No. 5760 2749e Seq. ID No. 5771 Seq. ID No. 5772 2750a Seq. ID No. 5773 Seq. ID No. 5774 2752 Seq. ID No. 5777 Seq. ID No. 5778 2753 Seq. ID No. 5779 Seq. ID No. 5780 2757a Seq. ID No. 5781 Seq. ID No. 5782 2758a Seq. ID No. 5785 Seq. ID No. 5786 2759a Seq. ID No. 5793 Seq. ID No. 5794 2760b Seq. ID No. 5799 Seq. ID No. 5800 2763a Seq. ID No. 5805 Seq. ID No. 5806 2764 Seq. ID No. 5811 Seq. ID No. 5812 2765c Seq. ID No. 5815 Seq. ID No. 5816 2766a Seq. ID No. 5817 Seq. ID No. 5818 2768b Seq. ID No. 5823 Seq. ID No. 5824 2771a Seq. ID No. 5831 Seq. ID No. 5832 2773 Seq. ID No. 5835 Seq. ID No. 5836 2774b Seq. ID No. 5839 Seq. ID No. 5840 2776a Seq. ID No. 5843 Seq. ID No. 5844 2777 Seq. ID No. 5847 Seq. ID No. 5848 2778 Seq. ID No. 5849 Seq. ID No. 5850 2779 Seq. ID No. 5851 Seq. ID No. 5852 2780 Seq. ID No. 5853 Seq. ID No. 5854 2784 Seq. ID No. 5855 Seq. ID No. 5856 2785a Seq. ID No. 5857 Seq. ID No. 5858 2786a Seq. ID No. 5861 Seq. ID No. 5862 2787a Seq. ID No. 5867 Seq. ID No. 5868 2789 Seq. ID No. 5875 Seq. ID No. 5876 2790 Seq. ID No. 5877 Seq. ID No. 5878 2793 Seq. ID No. 5881 Seq. ID No. 5882 2799a Seq. ID No. 5889 Seq. ID No. 5890 2801b Seq. ID No. 5895 Seq. ID No. 5896 2804 Seq. ID No. 5897 Seq. ID No. 5898 2805b Seq. ID No. 5901 Seq. ID No. 5902 2809 Seq. ID No. 5903 Seq. ID No. 5904 2810b Seq. ID No. 5907 Seq. ID No. 5908 2812 Seq. ID No. 5913 Seq. ID No. 5914 2814 Seq. ID No. 5915 Seq. ID No. 5916 2815 Seq. ID No. 5917 Seq. ID No. 5918 2816 Seq. ID No. 5919 Seq. ID No. 5920 2818c Seq. ID No. 5925 Seq. ID No. 5926 2819 Seq. ID No. 5931 Seq. ID No. 5932 2820 Seq. ID No. 5933 Seq. ID No. 5934 2821a Seq. ID No. 5935 Seq. ID No. 5936 2822b Seq. ID No. 5941 Seq. ID No. 5942 2823 Seq. ID No. 5943 Seq. ID No. 5944 2824a Seq. ID No. 5945 Seq. ID No. 5946 2829a Seq. ID No. 5949 Seq. ID No. 5950 2832 Seq. ID No. 5955 Seq. ID No. 5956 2833 Seq. ID No. 5957 Seq. ID No. 5958 2834a Seq. ID No. 5959 Seq. ID No. 5960 2842a Seq. ID No. 5967 Seq. ID No. 5968 2843a Seq. ID No. 5971 Seq. ID No. 5972 2845 Seq. ID No. 5975 Seq. ID No. 5976 2846a Seq. ID No. 5977 Seq. ID No. 5978 2848 Seq. ID No. 5981 Seq. ID No. 5982 2850 Seq. ID No. 5983 Seq. ID No. 5984 2851 Seq. ID No. 5985 Seq. ID No. 5986 2853 Seq. ID No. 5989 Seq. ID No. 5990 2854a Seq. ID No. 5991 Seq. ID No. 5992 2855 Seq. ID No. 5995 Seq. ID No. 5996 2856a Seq. ID No. 5997 Seq. ID No. 5998 2857 Seq. ID No. 6003 Seq. ID No. 6004 2859 Seq. ID No. 6005 Seq. ID No. 6006 2860a Seq. ID No. 6007 Seq. ID No. 6008 2863 Seq. ID No. 6015 Seq. ID No. 6016 2864 Seq. ID No. 6017 Seq. ID No. 6018 2868a Seq. ID No. 6019 Seq. ID No. 6020 2869a Seq. ID No. 6023 Seq. ID No. 6024 2871 Seq. ID No. 6029 Seq. ID No. 6030 2875 Seq. ID No. 6033 Seq. ID No. 6034 2877 Seq. ID No. 6035 Seq. ID No. 6036 2879a Seq. ID No. 6037 Seq. ID No. 6038 2881 Seq. ID No. 6043 Seq. ID No. 6044 2883b Seq. ID No. 6049 Seq. ID No. 6050 2886a Seq. ID No. 6055 Seq. ID No. 6056 2890 Seq. ID No. 6065 Seq. ID No. 6066 2891b Seq. ID No. 6069 Seq. ID No. 6070 2894a Seq. ID No. 6075 Seq. ID No. 6076 2895 Seq. ID No. 6081 Seq. ID No. 6082 2897a Seq. ID No. 6083 Seq. ID No. 6084 2900a Seq. ID No. 6087 Seq. ID No. 6088 2902 Seq. ID No. 6095 Seq. ID No. 6096 2904 Seq. ID No. 6097 Seq. ID No. 6098 2905a Seq. ID No. 6099 Seq. ID No. 6100 2906 Seq. ID No. 6103 Seq. ID No. 6104 2909a Seq. ID No. 6105 Seq. ID No. 6106 2912 Seq. ID No. 6113 Seq. ID No. 6114 2913a Seq. ID No. 6115 Seq. ID No. 6116 2915a Seq. ID No. 6119 Seq. ID No. 6120 2916 Seq. ID No. 6125 Seq. ID No. 6126 2917 Seq. ID No. 6127 Seq. ID No. 6128 2918 Seq. ID No. 6129 Seq. ID No. 6130 2920 Seq. ID No. 6131 Seq. ID No. 6132 2921 Seq. ID No. 6133 Seq. ID No. 6134 2923c Seq. ID No. 6141 Seq. ID No. 6142 2925a Seq. ID No. 6143 Seq. ID No. 6144 2926a Seq. ID No. 6147 Seq. ID No. 6148 2928a Seq. ID No. 6153 Seq. ID No. 6154 2931c Seq. ID No. 6165 Seq. ID No. 6166 2933b Seq. ID No. 6169 Seq. ID No. 6170 2934 Seq. ID No. 6171 Seq. ID No. 6172 2935a Seq. ID No. 6173 Seq. ID No. 6174 2936 Seq. ID No. 6177 Seq. ID No. 6178 2939a Seq. ID No. 6179 Seq. ID No. 6180 2941c Seq. ID No. 6187 Seq. ID No. 6188 2943c Seq. ID No. 6193 Seq. ID No. 6194 2947 Seq. ID No. 6201 Seq. ID No. 6202 2948c Seq. ID No. 6207 Seq. ID No. 6208 2950a Seq. ID No. 6211 Seq. ID No. 6212 2951 Seq. ID No. 6215 Seq. ID No. 6216 2954 Seq. ID No. 6219 Seq. ID No. 6220 2955f Seq. ID No. 6231 Seq. ID No. 6232 2957 Seq. ID No. 6235 Seq. ID No. 6236 2959 Seq. ID No. 6243 Seq. ID No. 6244 2962a Seq. ID No. 6247 Seq. ID No. 6248 2963 Seq. ID No. 6251 Seq. ID No. 6252 2965b Seq. ID No. 6255 Seq. ID No. 6256 2967 Seq. ID No. 6261 Seq. ID No. 6262 2969 Seq. ID No. 6263 Seq. ID No. 6264 2971a Seq. ID No. 6269 Seq. ID No. 6270 2974b Seq. ID No. 6275 Seq. ID No. 6276 2975 Seq. ID No. 6277 Seq. ID No. 6278 2977a Seq. ID No. 6279 Seq. ID No. 6280 2979 Seq. ID No. 6287 Seq. ID No. 6288 2980b Seq. ID No. 6291 Seq. ID No. 6292 2984 Seq. ID No. 6299 Seq. ID No. 6300 2986c Seq. ID No. 6305 Seq. ID No. 6306 2988a Seq. ID No. 6307 Seq. ID No. 6308 2989 Seq. ID No. 6313 Seq. ID No. 6314 2990 Seq. ID No. 6315 Seq. ID No. 6316 2991c Seq. ID No. 6321 Seq. ID No. 6322 2992 Seq. ID No. 6323 Seq. ID No. 6324 2993a Seq. ID No. 6325 Seq. ID No. 6326 2995b Seq. ID No. 6331 Seq. ID No. 6332 2998a Seq. ID No. 6335 Seq. ID No. 6336 2999 Seq. ID No. 6339 Seq. ID No. 6340 3001 Seq. ID No. 6341 Seq. ID No. 6342 3003 Seq. ID No. 6343 Seq. ID No. 6344 3005 Seq. ID No. 6345 Seq. ID No. 6346 3008a Seq. ID No. 6347 Seq. ID No. 6348 3010a Seq. ID No. 6355 Seq. ID No. 6356 3012 Seq. ID No. 6359 Seq. ID No. 6360 3015 Seq. ID No. 6361 Seq. ID No. 6362 3016b Seq. ID No. 6365 Seq. ID No. 6366 3017 Seq. ID No. 6369 Seq. ID No. 6370 3018a Seq. ID No. 6371 Seq. ID No. 6372 3020 Seq. ID No. 6375 Seq. ID No. 6376 3021 Seq. ID No. 6377 Seq. ID No. 6378 3022 Seq. ID No. 6379 Seq. ID No. 6380 3026a Seq. ID No. 6387 Seq. ID No. 6388 3028a Seq. ID No. 6391 Seq. ID No. 6392 3029a Seq. ID No. 6397 Seq. ID No. 6398 3031a Seq. ID No. 6401 Seq. ID No. 6402 3032a Seq. ID No. 6405 Seq. ID No. 6406 3033a Seq. ID No. 6409 Seq. ID No. 6410 3035 Seq. ID No. 6413 Seq. ID No. 6414 3037b Seq. ID No. 6417 Seq. ID No. 6418 3038 Seq. ID No. 6419 Seq. ID No. 6420 3040b Seq. ID No. 6423 Seq. ID No. 6424 3043a Seq. ID No. 6429 Seq. ID No. 6430 3044 Seq. ID No. 6433 Seq. ID No. 6434 3045a Seq. ID No. 6435 Seq. ID No. 6436 3048a Seq. ID No. 6439 Seq. ID No. 6440 3049c Seq. ID No. 6445 Seq. ID No. 6446 3051a Seq. ID No. 6447 Seq. ID No. 6448 3052 Seq. ID No. 6451 Seq. ID No. 6452 3055a Seq. ID No. 6455 Seq. ID No. 6456 3057 Seq. ID No. 6459 Seq. ID No. 6460 3059 Seq. ID No. 6461 Seq. ID No. 6462 3060 Seq. ID No. 6463 Seq. ID No. 6464 3065a Seq. ID No. 6475 Seq. ID No. 6476 3067 Seq. ID No. 6481 Seq. ID No. 6482 3068 Seq. ID No. 6483 Seq. ID No. 6484 3069 Seq. ID No. 6485 Seq. ID No. 6486 3071 Seq. ID No. 6487 Seq. ID No. 6488 3072a Seq. ID No. 6489 Seq. ID No. 6490 3073 Seq. ID No. 6491 Seq. ID No. 6492 3074 Seq. ID No. 6493 Seq. ID No. 6494 3075 Seq. ID No. 6495 Seq. ID No. 6496 3077a Seq. ID No. 6499 Seq. ID No. 6500 3078 Seq. ID No. 6505 Seq. ID No. 6506 3081a Seq. ID No. 6509 Seq. ID No. 6510 3083c Seq. ID No. 6513 Seq. ID No. 6514 3086 Seq. ID No. 6519 Seq. ID No. 6520 3087a Seq. ID No. 6521 Seq. ID No. 6522 3088 Seq. ID No. 6525 Seq. ID No. 6526 3089a Seq. ID No. 6527 Seq. ID No. 6528 3090 Seq. ID No. 6531 Seq. ID No. 6532 3091 Seq. ID No. 6533 Seq. ID No. 6534 3092a Seq. ID No. 6535 Seq. ID No. 6536 3097 Seq. ID No. 6545 Seq. ID No. 6546 3098c Seq. ID No. 6551 Seq. ID No. 6552 3099 Seq. ID No. 6553 Seq. ID No. 6554 3101 Seq. ID No. 6559 Seq. ID No. 6560 3102 Seq. ID No. 6561 Seq. ID No. 6562 3103b Seq. ID No. 6563 Seq. ID No. 6564 3104 Seq. ID No. 6565 Seq. ID No. 6566 3105 Seq. ID No. 6567 Seq. ID No. 6568 3106 Seq. ID No. 6569 Seq. ID No. 6570 3108a Seq. ID No. 6575 Seq. ID No. 6576 3109 Seq. ID No. 6579 Seq. ID No. 6580 3110b Seq. ID No. 6583 Seq. ID No. 6584 3113 Seq. ID No. 6585 Seq. ID No. 6586 3118b Seq. ID No. 6591 Seq. ID No. 6592 3119b Seq. ID No. 6595 Seq. ID No. 6596 3121 Seq. ID No. 6605 Seq. ID No. 6606 3122a Seq. ID No. 6607 Seq. ID No. 6608 3123a Seq. ID No. 6611 Seq. ID No. 6612 3124 Seq. ID No. 6615 Seq. ID No. 6616 3126 Seq. ID No. 6617 Seq. ID No. 6618 3129a Seq. ID No. 6619 Seq. ID No. 6620 3131 Seq. ID No. 6623 Seq. ID No. 6624 3134a Seq. ID No. 6625 Seq. ID No. 6626 3138 Seq. ID No. 6629 Seq. ID No. 6630 3141 Seq. ID No. 6633 Seq. ID No. 6634 3145a Seq. ID No. 6635 Seq. ID No. 6636 3147a Seq. ID No. 6641 Seq. ID No. 6642 3149a Seq. ID No. 6647 Seq. ID No. 6648

Listed in Table 20 are 2343 ORFs detected by the ORF finder program of Applicant's assignee that searches for one of the three potential Start codons between a Stop-Stop region. It first looks for a ‘ATG’ Start codon but will accept either a ‘GTG’ or ‘TTG’ Start codon if found first. TABLE 20 WYETH ORFs ORF Number DNA SEQ ID Number Protein SEQ ID Number 1 Seq. ID No. 1 Seq. ID No. 2 2b Seq. ID No. 5 Seq. ID No. 6 4c Seq. ID No. 11 Seq. ID No. 12 5 Seq. ID No. 13 Seq. ID No. 14 7 Seq. ID No. 15 Seq. ID No. 16 10 Seq. ID No. 17 Seq. ID No. 18 11 Seq. ID No. 19 Seq. ID No. 20 13a Seq. ID No. 21 Seq. ID No. 22 16 Seq. ID No. 23 Seq. ID No. 24 18 Seq. ID No. 27 Seq. ID No. 28 20 Seq. ID No. 29 Seq. ID No. 30 21b Seq. ID No. 31 Seq. ID No. 32 23b Seq. ID No. 35 Seq. ID No. 36 24 Seq. ID No. 37 Seq. ID No. 38 36 Seq. ID No. 41 Seq. ID No. 42 37 Seq. ID No. 43 Seq. ID No. 44 38a Seq. ID No. 45 Seq. ID No. 46 38b Seq. ID No. 47 Seq. ID No. 48 39a Seq. ID No. 49 Seq. ID No. 50 39b Seq. ID No. 51 Seq. ID No. 52 40 Seq. ID No. 53 Seq. ID No. 54 41a Seq. ID No. 55 Seq. ID No. 56 41b Seq. ID No. 57 Seq. ID No. 58 41c Seq. ID No. 59 Seq. ID No. 60 44a Seq. ID No. 65 Seq. ID No. 66 44b Seq. ID No. 67 Seq. ID No. 68 47 Seq. ID No. 75 Seq. ID No. 76 48a Seq. ID No. 77 Seq. ID No. 78 48b Seq. ID No. 79 Seq. ID No. 80 48c Seq. ID No. 81 Seq. ID No. 82 50 Seq. ID No. 83 Seq. ID No. 84 51c Seq. ID No. 89 Seq. ID No. 90 55 Seq. ID No. 91 Seq. ID No. 92 56b Seq. ID No. 93 Seq. ID No. 94 57b Seq. ID No. 97 Seq. ID No. 98 58 Seq. ID No. 99 Seq. ID No. 100 60b Seq. ID No. 103 Seq. ID No. 104 61 Seq. ID No. 105 Seq. ID No. 106 62a Seq. ID No. 107 Seq. ID No. 108 62b Seq. ID No. 109 Seq. ID No. 110 62c Seq. ID No. 111 Seq. ID No. 112 63a Seq. ID No. 113 Seq. ID No. 114 63b Seq. ID No. 115 Seq. ID No. 116 65a Seq. ID No. 117 Seq. ID No. 118 65b Seq. ID No. 119 Seq. ID No. 120 65c Seq. ID No. 121 Seq. ID No. 122 69 Seq. ID No. 127 Seq. ID No. 128 71 Seq. ID No. 129 Seq. ID No. 130 73a Seq. ID No. 131 Seq. ID No. 132 73b Seq. ID No. 133 Seq. ID No. 134 74 Seq. ID No. 135 Seq. ID No. 136 77 Seq. ID No. 137 Seq. ID No. 138 79 Seq. ID No. 139 Seq. ID No. 140 80b Seq. ID No. 143 Seq. ID No. 144 80c Seq. ID No. 145 Seq. ID No. 146 81a Seq. ID No. 147 Seq. ID No. 148 81b Seq. ID No. 149 Seq. ID No. 150 85a Seq. ID No. 153 Seq. ID No. 154 85b Seq. ID No. 155 Seq. ID No. 156 85c Seq. ID No. 157 Seq. ID No. 158 86 Seq. ID No. 159 Seq. ID No. 160 87a Seq. ID No. 161 Seq. ID No. 162 87b Seq. ID No. 163 Seq. ID No. 164 87c Seq. ID No. 165 Seq. ID No. 166 88 Seq. ID No. 167 Seq. ID No. 168 89 Seq. ID No. 169 Seq. ID No. 170 91a Seq. ID No. 171 Seq. ID No. 172 91c Seq. ID No. 175 Seq. ID No. 176 91d Seq. ID No. 177 Seq. ID No. 178 93a Seq. ID No. 179 Seq. ID No. 180 93b Seq. ID No. 181 Seq. ID No. 182 93c Seq. ID No. 183 Seq. ID No. 184 95b Seq. ID No. 187 Seq. ID No. 188 99 Seq. ID No. 191 Seq. ID No. 192 101 Seq. ID No. 193 Seq. ID No. 194 102 Seq. ID No. 195 Seq. ID No. 196 104c Seq. ID No. 201 Seq. ID No. 202 105b Seq. ID No. 205 Seq. ID No. 206 106 Seq. ID No. 207 Seq. ID No. 208 109d Seq. ID No. 215 Seq. ID No. 216 111b Seq. ID No. 219 Seq. ID No. 220 112a Seq. ID No. 221 Seq. ID No. 222 112b Seq. ID No. 223 Seq. ID No. 224 114 Seq. ID No. 225 Seq. ID No. 226 115 Seq. ID No. 227 Seq. ID No. 228 119b Seq. ID No. 231 Seq. ID No. 232 121 Seq. ID No. 233 Seq. ID No. 234 124c Seq. ID No. 239 Seq. ID No. 240 127a Seq. ID No. 243 Seq. ID No. 244 127b Seq. ID No. 245 Seq. ID No. 246 127c Seq. ID No. 247 Seq. ID No. 248 129c Seq. ID No. 253 Seq. ID No. 254 132b Seq. ID No. 257 Seq. ID No. 258 132c Seq. ID No. 259 Seq. ID No. 260 134 Seq. ID No. 261 Seq. ID No. 262 135a Seq. ID No. 263 Seq. ID No. 264 135b Seq. ID No. 265 Seq. ID No. 266 137a Seq. ID No. 267 Seq. ID No. 268 137b Seq. ID No. 269 Seq. ID No. 270 138b Seq. ID No. 273 Seq. ID No. 274 143 Seq. ID No. 277 Seq. ID No. 278 144a Seq. ID No. 279 Seq. ID No. 280 144b Seq. ID No. 281 Seq. ID No. 282 144c Seq. ID No. 283 Seq. ID No. 284 145d Seq. ID No. 291 Seq. ID No. 292 147 Seq. ID No. 293 Seq. ID No. 294 151b Seq. ID No. 297 Seq. ID No. 298 152b Seq. ID No. 301 Seq. ID No. 302 153b Seq. ID No. 305 Seq. ID No. 306 153c Seq. ID No. 307 Seq. ID No. 308 154 Seq. ID No. 309 Seq. ID No. 310 155b Seq. ID No. 313 Seq. ID No. 314 157b Seq. ID No. 317 Seq. ID No. 318 158b Seq. ID No. 321 Seq. ID No. 322 160a Seq. ID No. 323 Seq. ID No. 324 160b Seq. ID No. 325 Seq. ID No. 326 162c Seq. ID No. 331 Seq. ID No. 332 162d Seq. ID No. 333 Seq. ID No. 334 162e Seq. ID No. 335 Seq. ID No. 336 163 Seq. ID No. 337 Seq. ID No. 338 164 Seq. ID No. 339 Seq. ID No. 340 165b Seq. ID No. 343 Seq. ID No. 344 167 Seq. ID No. 345 Seq. ID No. 346 169 Seq. ID No. 347 Seq. ID No. 348 170 Seq. ID No. 349 Seq. ID No. 350 171b Seq. ID No. 353 Seq. ID No. 354 172 Seq. ID No. 355 Seq. ID No. 356 173 Seq. ID No. 357 Seq. ID No. 358 174 Seq. ID No. 359 Seq. ID No. 360 175 Seq. ID No. 361 Seq. ID No. 362 176 Seq. ID No. 363 Seq. ID No. 364 177a Seq. ID No. 365 Seq. ID No. 366 177b Seq. ID No. 367 Seq. ID No. 368 179a Seq. ID No. 369 Seq. ID No. 370 179b Seq. ID No. 371 Seq. ID No. 372 180b Seq. ID No. 375 Seq. ID No. 376 183a Seq. ID No. 377 Seq. ID No. 378 184 Seq. ID No. 379 Seq. ID No. 380 186 Seq. ID No. 383 Seq. ID No. 384 187a Seq. ID No. 385 Seq. ID No. 386 187b Seq. ID No. 387 Seq. ID No. 388 188 Seq. ID No. 389 Seq. ID No. 390 189b Seq. ID No. 391 Seq. ID No. 392 191b Seq. ID No. 393 Seq. ID No. 394 192b Seq. ID No. 397 Seq. ID No. 398 194a Seq. ID No. 401 Seq. ID No. 402 194b Seq. ID No. 403 Seq. ID No. 404 195 Seq. ID No. 405 Seq. ID No. 406 196 Seq. ID No. 407 Seq. ID No. 408 197a Seq. ID No. 409 Seq. ID No. 410 198b Seq. ID No. 415 Seq. ID No. 416 203 Seq. ID No. 423 Seq. ID No. 424 204 Seq. ID No. 425 Seq. ID No. 426 205 Seq. ID No. 427 Seq. ID No. 428 206 Seq. ID No. 429 Seq. ID No. 430 207 Seq. ID No. 431 Seq. ID No. 432 208a Seq. ID No. 433 Seq. ID No. 434 208b Seq. ID No. 435 Seq. ID No. 436 210 Seq. ID No. 437 Seq. ID No. 438 211 Seq. ID No. 439 Seq. ID No. 440 213 Seq. ID No. 441 Seq. ID No. 442 215a Seq. ID No. 443 Seq. ID No. 444 218 Seq. ID No. 445 Seq. ID No. 446 219 Seq. ID No. 447 Seq. ID No. 448 220b Seq. ID No. 451 Seq. ID No. 452 220c Seq. ID No. 453 Seq. ID No. 454 223a Seq. ID No. 455 Seq. ID No. 456 223b Seq. ID No. 457 Seq. ID No. 458 226b Seq. ID No. 461 Seq. ID No. 462 227 Seq. ID No. 463 Seq. ID No. 464 228b Seq. ID No. 467 Seq. ID No. 468 228c Seq. ID No. 469 Seq. ID No. 470 228d Seq. ID No. 471 Seq. ID No. 472 232a Seq. ID No. 473 Seq. ID No. 474 232b Seq. ID No. 475 Seq. ID No. 476 235a Seq. ID No. 477 Seq. ID No. 478 235b Seq. ID No. 479 Seq. ID No. 480 236a Seq. ID No. 481 Seq. ID No. 482 236b Seq. ID No. 483 Seq. ID No. 484 236c Seq. ID No. 485 Seq. ID No. 486 239b Seq. ID No. 489 Seq. ID No. 490 239c Seq. ID No. 491 Seq. ID No. 492 240 Seq. ID No. 493 Seq. ID No. 494 241 Seq. ID No. 495 Seq. ID No. 496 245c Seq. ID No. 501 Seq. ID No. 502 246b Seq. ID No. 505 Seq. ID No. 506 247 Seq. ID No. 507 Seq. ID No. 508 248b Seq. ID No. 511 Seq. ID No. 512 249b Seq. ID No. 515 Seq. ID No. 516 251 Seq. ID No. 517 Seq. ID No. 518 254 Seq. ID No. 523 Seq. ID No. 524 255c Seq. ID No. 529 Seq. ID No. 530 255d Seq. ID No. 531 Seq. ID No. 532 258 Seq. ID No. 533 Seq. ID No. 534 259b Seq. ID No. 537 Seq. ID No. 538 259c Seq. ID No. 539 Seq. ID No. 540 262 Seq. ID No. 543 Seq. ID No. 544 263b Seq. ID No. 547 Seq. ID No. 548 264b Seq. ID No. 549 Seq. ID No. 550 265 Seq. ID No. 551 Seq. ID No. 552 267b Seq. ID No. 553 Seq. ID No. 554 267c Seq. ID No. 555 Seq. ID No. 556 268 Seq. ID No. 557 Seq. ID No. 558 269a Seq. ID No. 559 Seq. ID No. 560 269b Seq. ID No. 561 Seq. ID No. 562 271b Seq. ID No. 565 Seq. ID No. 566 273b Seq. ID No. 569 Seq. ID No. 570 277a Seq. ID No. 571 Seq. ID No. 572 277b Seq. ID No. 573 Seq. ID No. 574 277c Seq. ID No. 575 Seq. ID No. 576 279b Seq. ID No. 579 Seq. ID No. 580 280a Seq. ID No. 581 Seq. ID No. 582 280c Seq. ID No. 585 Seq. ID No. 586 280d Seq. ID No. 587 Seq. ID No. 588 282 Seq. ID No. 589 Seq. ID No. 590 283a Seq. ID No. 591 Seq. ID No. 592 283b Seq. ID No. 593 Seq. ID No. 594 284a Seq. ID No. 595 Seq. ID No. 596 284b Seq. ID No. 597 Seq. ID No. 598 285b Seq. ID No. 599 Seq. ID No. 600 286a Seq. ID No. 601 Seq. ID No. 602 286b Seq. ID No. 603 Seq. ID No. 604 287 Seq. ID No. 605 Seq. ID No. 606 290b Seq. ID No. 609 Seq. ID No. 610 294 Seq. ID No. 613 Seq. ID No. 614 296 Seq. ID No. 615 Seq. ID No. 616 297 Seq. ID No. 617 Seq. ID No. 618 300b Seq. ID No. 619 Seq. ID No. 620 301a Seq. ID No. 621 Seq. ID No. 622 301b Seq. ID No. 623 Seq. ID No. 624 304a Seq. ID No. 625 Seq. ID No. 626 304b Seq. ID No. 627 Seq. ID No. 628 310 Seq. ID No. 635 Seq. ID No. 636 311 Seq. ID No. 637 Seq. ID No. 638 313c Seq. ID No. 643 Seq. ID No. 644 313d Seq. ID No. 645 Seq. ID No. 646 313e Seq. ID No. 647 Seq. ID No. 648 315 Seq. ID No. 649 Seq. ID No. 650 317b Seq. ID No. 655 Seq. ID No. 656 318d Seq. ID No. 663 Seq. ID No. 664 318e Seq. ID No. 665 Seq. ID No. 666 320 Seq. ID No. 667 Seq. ID No. 668 321 Seq. ID No. 669 Seq. ID No. 670 324 Seq. ID No. 675 Seq. ID No. 676 327c Seq. ID No. 681 Seq. ID No. 682 329 Seq. ID No. 683 Seq. ID No. 684 330b Seq. ID No. 687 Seq. ID No. 688 330c Seq. ID No. 689 Seq. ID No. 690 331 Seq. ID No. 691 Seq. ID No. 692 333 Seq. ID No. 695 Seq. ID No. 696 334 Seq. ID No. 697 Seq. ID No. 698 335a Seq. ID No. 699 Seq. ID No. 700 335b Seq. ID No. 701 Seq. ID No. 702 337 Seq. ID No. 703 Seq. ID No. 704 338a Seq. ID No. 705 Seq. ID No. 706 338b Seq. ID No. 707 Seq. ID No. 708 338c Seq. ID No. 709 Seq. ID No. 710 341b Seq. ID No. 713 Seq. ID No. 714 342f Seq. ID No. 725 Seq. ID No. 726 342g Seq. ID No. 727 Seq. ID No. 728 342h Seq. ID No. 729 Seq. ID No. 730 344a Seq. ID No. 731 Seq. ID No. 732 344b Seq. ID No. 733 Seq. ID No. 734 345 Seq. ID No. 735 Seq. ID No. 736 346b Seq. ID No. 739 Seq. ID No. 740 347 Seq. ID No. 741 Seq. ID No. 742 349b Seq. ID No. 745 Seq. ID No. 746 349c Seq. ID No. 747 Seq. ID No. 748 350a Seq. ID No. 749 Seq. ID No. 750 350b Seq. ID No. 751 Seq. ID No. 752 351 Seq. ID No. 753 Seq. ID No. 754 352c Seq. ID No. 759 Seq. ID No. 760 354b Seq. ID No. 763 Seq. ID No. 764 354c Seq. ID No. 765 Seq. ID No. 766 356c Seq. ID No. 773 Seq. ID No. 774 356d Seq. ID No. 775 Seq. ID No. 776 358c Seq. ID No. 781 Seq. ID No. 782 362 Seq. ID No. 783 Seq. ID No. 784 365b Seq. ID No. 787 Seq. ID No. 788 367a Seq. ID No. 793 Seq. ID No. 794 367b Seq. ID No. 795 Seq. ID No. 796 371b Seq. ID No. 799 Seq. ID No. 800 372a Seq. ID No. 801 Seq. ID No. 802 372c Seq. ID No. 805 Seq. ID No. 806 372d Seq. ID No. 807 Seq. ID No. 808 374 Seq. ID No. 809 Seq. ID No. 810 377a Seq. ID No. 811 Seq. ID No. 812 377b Seq. ID No. 813 Seq. ID No. 814 378a Seq. ID No. 815 Seq. ID No. 816 378b Seq. ID No. 817 Seq. ID No. 818 382b Seq. ID No. 819 Seq. ID No. 820 383a Seq. ID No. 821 Seq. ID No. 822 383b Seq. ID No. 823 Seq. ID No. 824 384b Seq. ID No. 827 Seq. ID No. 828 385a Seq. ID No. 829 Seq. ID No. 830 385b Seq. ID No. 831 Seq. ID No. 832 387 Seq. ID No. 835 Seq. ID No. 836 390 Seq. ID No. 837 Seq. ID No. 838 391 Seq. ID No. 839 Seq. ID No. 840 395a Seq. ID No. 843 Seq. ID No. 844 395b Seq. ID No. 845 Seq. ID No. 846 395c Seq. ID No. 847 Seq. ID No. 848 400b Seq. ID No. 855 Seq. ID No. 856 401b Seq. ID No. 859 Seq. ID No. 860 403a Seq. ID No. 861 Seq. ID No. 862 403c Seq. ID No. 865 Seq. ID No. 866 403d Seq. ID No. 867 Seq. ID No. 868 406b Seq. ID No. 871 Seq. ID No. 872 409a Seq. ID No. 873 Seq. ID No. 874 409b Seq. ID No. 875 Seq. ID No. 876 410a Seq. ID No. 877 Seq. ID No. 878 410b Seq. ID No. 879 Seq. ID No. 880 410c Seq. ID No. 881 Seq. ID No. 882 413b Seq. ID No. 885 Seq. ID No. 886 418b Seq. ID No. 895 Seq. ID No. 896 419a Seq. ID No. 897 Seq. ID No. 898 419b Seq. ID No. 899 Seq. ID No. 900 419c Seq. ID No. 901 Seq. ID No. 902 420a Seq. 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ID No. 1047 Seq. ID No. 1048 478a Seq. ID No. 1049 Seq. ID No. 1050 478b Seq. ID No. 1051 Seq. ID No. 1052 480b Seq. ID No. 1057 Seq. ID No. 1058 481a Seq. ID No. 1059 Seq. ID No. 1060 481b Seq. ID No. 1061 Seq. ID No. 1062 482b Seq. ID No. 1065 Seq. ID No. 1066 490 Seq. ID No. 1069 Seq. ID No. 1070 492 Seq. ID No. 1075 Seq. ID No. 1076 494a Seq. ID No. 1077 Seq. ID No. 1078 495a Seq. ID No. 1079 Seq. ID No. 1080 495b Seq. ID No. 1081 Seq. ID No. 1082 495c Seq. ID No. 1083 Seq. ID No. 1084 498a Seq. ID No. 1085 Seq. ID No. 1086 498b Seq. ID No. 1087 Seq. ID No. 1088 499b Seq. ID No. 1091 Seq. ID No. 1092 500 Seq. ID No. 1093 Seq. ID No. 1094 502b Seq. ID No. 1095 Seq. ID No. 1096 502c Seq. ID No. 1097 Seq. ID No. 1098 504 Seq. ID No. 1099 Seq. ID No. 1100 505a Seq. ID No. 1101 Seq. ID No. 1102 505b Seq. ID No. 1103 Seq. ID No. 1104 507b Seq. ID No. 1107 Seq. ID No. 1108 509 Seq. ID No. 1109 Seq. ID No. 1110 510 Seq. ID No. 1111 Seq. ID No. 1112 512a Seq. ID No. 1113 Seq. 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ID No. 1179 Seq. ID No. 1180 544 Seq. ID No. 1181 Seq. ID No. 1182 545c Seq. ID No. 1187 Seq. ID No. 1188 546b Seq. ID No. 1191 Seq. ID No. 1192 546c Seq. ID No. 1193 Seq. ID No. 1194 547a Seq. ID No. 1195 Seq. ID No. 1196 547b Seq. ID No. 1197 Seq. ID No. 1198 549b Seq. ID No. 1201 Seq. ID No. 1202 550a Seq. ID No. 1203 Seq. ID No. 1204 551 Seq. ID No. 1205 Seq. ID No. 1206 553c Seq. ID No. 1207 Seq. ID No. 1208 554b Seq. ID No. 1211 Seq. ID No. 1212 556 Seq. ID No. 1213 Seq. ID No. 1214 557a Seq. ID No. 1215 Seq. ID No. 1216 557b Seq. ID No. 1217 Seq. ID No. 1218 560b Seq. ID No. 1221 Seq. ID No. 1222 561 Seq. ID No. 1223 Seq. ID No. 1224 563 Seq. ID No. 1225 Seq. ID No. 1226 564c Seq. ID No. 1231 Seq. ID No. 1232 569 Seq. ID No. 1233 Seq. ID No. 1234 570b Seq. ID No. 1237 Seq. ID No. 1238 571 Seq. ID No. 1239 Seq. ID No. 1240 573 Seq. ID No. 1241 Seq. ID No. 1242 576b Seq. ID No. 1245 Seq. ID No. 1246 578a Seq. ID No. 1247 Seq. ID No. 1248 578b Seq. ID No. 1249 Seq. ID No. 1250 580a Seq. ID No. 1251 Seq. ID No. 1252 580b Seq. ID No. 1253 Seq. ID No. 1254 583a Seq. ID No. 1255 Seq. ID No. 1256 583b Seq. ID No. 1257 Seq. ID No. 1258 585b Seq. ID No. 1259 Seq. ID No. 1260 586a Seq. ID No. 1261 Seq. ID No. 1262 586b Seq. ID No. 1263 Seq. ID No. 1264 587d Seq. ID No. 1271 Seq. ID No. 1272 588a Seq. ID No. 1273 Seq. ID No. 1274 588b Seq. ID No. 1275 Seq. ID No. 1276 589a Seq. ID No. 1277 Seq. ID No. 1278 589b Seq. ID No. 1279 Seq. ID No. 1280 595b Seq. ID No. 1285 Seq. ID No. 1286 596b Seq. ID No. 1289 Seq. ID No. 1290 596c Seq. ID No. 1291 Seq. ID No. 1292 597 Seq. ID No. 1293 Seq. ID No. 1294 598a Seq. ID No. 1295 Seq. ID No. 1296 598b Seq. ID No. 1297 Seq. ID No. 1298 599a Seq. ID No. 1299 Seq. ID No. 1300 599b Seq. ID No. 1301 Seq. ID No. 1302 600a Seq. ID No. 1303 Seq. ID No. 1304 600b Seq. ID No. 1305 Seq. ID No. 1306 603a Seq. ID No. 1307 Seq. ID No. 1308 606 Seq. ID No. 1309 Seq. ID No. 1310 607a Seq. ID No. 1311 Seq. ID No. 1312 607b Seq. ID No. 1313 Seq. ID No. 1314 609b Seq. ID No. 1317 Seq. ID No. 1318 610a Seq. ID No. 1319 Seq. ID No. 1320 610b Seq. ID No. 1321 Seq. ID No. 1322 613d Seq. ID No. 1331 Seq. ID No. 1332 614a Seq. ID No. 1333 Seq. ID No. 1334 614b Seq. ID No. 1335 Seq. ID No. 1336 615b Seq. ID No. 1337 Seq. ID No. 1338 618 Seq. ID No. 1339 Seq. ID No. 1340 619b Seq. ID No. 1343 Seq. ID No. 1344 620 Seq. ID No. 1345 Seq. ID No. 1346 623 Seq. ID No. 1347 Seq. ID No. 1348 624a Seq. ID No. 1349 Seq. ID No. 1350 624b Seq. ID No. 1351 Seq. ID No. 1352 626b Seq. ID No. 1359 Seq. ID No. 1360 626c Seq. ID No. 1361 Seq. ID No. 1362 631a Seq. ID No. 1363 Seq. ID No. 1364 631b Seq. ID No. 1365 Seq. ID No. 1366 631d Seq. ID No. 1369 Seq. ID No. 1370 632b Seq. ID No. 1371 Seq. ID No. 1372 633b Seq. ID No. 1375 Seq. ID No. 1376 633c Seq. ID No. 1377 Seq. ID No. 1378 636 Seq. ID No. 1381 Seq. ID No. 1382 637a Seq. ID No. 1383 Seq. ID No. 1384 637b Seq. ID No. 1385 Seq. ID No. 1386 637c Seq. ID No. 1387 Seq. ID No. 1388 640 Seq. ID No. 1389 Seq. ID No. 1390 641a Seq. ID No. 1391 Seq. ID No. 1392 641b Seq. ID No. 1393 Seq. ID No. 1394 645 Seq. ID No. 1401 Seq. ID No. 1402 650 Seq. ID No. 1403 Seq. ID No. 1404 653a Seq. ID No. 1407 Seq. ID No. 1408 653b Seq. ID No. 1409 Seq. ID No. 1410 653c Seq. ID No. 1411 Seq. ID No. 1412 656 Seq. ID No. 1413 Seq. ID No. 1414 657c Seq. ID No. 1415 Seq. ID No. 1416 658b Seq. ID No. 1419 Seq. ID No. 1420 659a Seq. ID No. 1421 Seq. ID No. 1422 659b Seq. ID No. 1423 Seq. ID No. 1424 661 Seq. ID No. 1425 Seq. ID No. 1426 663 Seq. ID No. 1427 Seq. ID No. 1428 665 Seq. ID No. 1429 Seq. ID No. 1430 670 Seq. ID No. 1433 Seq. ID No. 1434 674b Seq. ID No. 1437 Seq. ID No. 1438 677a Seq. ID No. 1441 Seq. ID No. 1442 677b Seq. ID No. 1443 Seq. ID No. 1444 679b Seq. ID No. 1447 Seq. ID No. 1448 680 Seq. ID No. 1449 Seq. ID No. 1450 681 Seq. ID No. 1451 Seq. ID No. 1452 683b Seq. ID No. 1455 Seq. ID No. 1456 687 Seq. ID No. 1459 Seq. ID No. 1460 688b Seq. ID No. 1463 Seq. ID No. 1464 690 Seq. ID No. 1465 Seq. ID No. 1466 691a Seq. ID No. 1467 Seq. ID No. 1468 691b Seq. ID No. 1469 Seq. ID No. 1470 692 Seq. ID No. 1471 Seq. ID No. 1472 694 Seq. ID No. 1473 Seq. ID No. 1474 696 Seq. ID No. 1475 Seq. ID No. 1476 698 Seq. ID No. 1477 Seq. ID No. 1478 699b Seq. ID No. 1479 Seq. ID No. 1480 700b Seq. ID No. 1483 Seq. ID No. 1484 700c Seq. ID No. 1485 Seq. ID No. 1486 703 Seq. ID No. 1487 Seq. ID No. 1488 705b Seq. ID No. 1491 Seq. ID No. 1492 707 Seq. ID No. 1493 Seq. ID No. 1494 709 Seq. ID No. 1495 Seq. ID No. 1496 710 Seq. ID No. 1497 Seq. ID No. 1498 712a Seq. ID No. 1499 Seq. ID No. 1500 712b Seq. ID No. 1501 Seq. ID No. 1502 715b Seq. ID No. 1505 Seq. ID No. 1506 717 Seq. ID No. 1507 Seq. ID No. 1508 721 Seq. ID No. 1511 Seq. ID No. 1512 722c Seq. ID No. 1517 Seq. ID No. 1518 724a Seq. ID No. 1519 Seq. ID No. 1520 724c Seq. ID No. 1523 Seq. ID No. 1524 724d Seq. ID No. 1525 Seq. ID No. 1526 726 Seq. ID No. 1527 Seq. ID No. 1528 728b Seq. ID No. 1531 Seq. ID No. 1532 730d Seq. ID No. 1539 Seq. ID No. 1540 732 Seq. ID No. 1543 Seq. ID No. 1544 738c Seq. ID No. 1549 Seq. ID No. 1550 739 Seq. ID No. 1551 Seq. ID No. 1552 740 Seq. ID No. 1553 Seq. ID No. 1554 741a Seq. ID No. 1555 Seq. ID No. 1556 741b Seq. ID No. 1557 Seq. ID No. 1558 743b Seq. ID No. 1561 Seq. ID No. 1562 744 Seq. ID No. 1563 Seq. ID No. 1564 745a Seq. ID No. 1565 Seq. ID No. 1566 745b Seq. ID No. 1567 Seq. ID No. 1568 746b Seq. ID No. 1571 Seq. ID No. 1572 747 Seq. ID No. 1573 Seq. ID No. 1574 748a Seq. ID No. 1575 Seq. ID No. 1576 748b Seq. ID No. 1577 Seq. ID No. 1578 749 Seq. ID No. 1579 Seq. ID No. 1580 751 Seq. ID No. 1581 Seq. ID No. 1582 754d Seq. ID No. 1589 Seq. ID No. 1590 756b Seq. ID No. 1593 Seq. ID No. 1594 758 Seq. ID No. 1595 Seq. ID No. 1596 760 Seq. ID No. 1597 Seq. ID No. 1598 762a Seq. ID No. 1599 Seq. ID No. 1600 762b Seq. ID No. 1601 Seq. ID No. 1602 763b Seq. ID No. 1607 Seq. ID No. 1608 766 Seq. ID No. 1611 Seq. ID No. 1612 767 Seq. ID No. 1613 Seq. ID No. 1614 770a Seq. ID No. 1615 Seq. ID No. 1616 770b Seq. ID No. 1617 Seq. ID No. 1618 770c Seq. ID No. 1619 Seq. ID No. 1620 772b Seq. ID No. 1623 Seq. ID No. 1624 774 Seq. ID No. 1625 Seq. ID No. 1626 775 Seq. ID No. 1627 Seq. ID No. 1628 779 Seq. ID No. 1633 Seq. ID No. 1634 780b Seq. ID No. 1637 Seq. ID No. 1638 782b Seq. ID No. 1639 Seq. ID No. 1640 785 Seq. ID No. 1641 Seq. ID No. 1642 786b Seq. ID No. 1643 Seq. ID No. 1644 788b Seq. ID No. 1647 Seq. ID No. 1648 789b Seq. ID No. 1651 Seq. ID No. 1652 789c Seq. ID No. 1653 Seq. ID No. 1654 791 Seq. ID No. 1655 Seq. ID No. 1656 792 Seq. ID No. 1657 Seq. ID No. 1658 794b Seq. ID No. 1661 Seq. ID No. 1662 794c Seq. ID No. 1663 Seq. ID No. 1664 794d Seq. ID No. 1665 Seq. ID No. 1666 797 Seq. ID No. 1669 Seq. ID No. 1670 799c Seq. ID No. 1675 Seq. ID No. 1676 799e Seq. ID No. 1679 Seq. ID No. 1680 799f Seq. ID No. 1681 Seq. ID No. 1682 803b Seq. ID No. 1685 Seq. 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ID No. 1890 939c Seq. ID No. 1895 Seq. ID No. 1896 944b Seq. ID No. 1903 Seq. ID No. 1904 946 Seq. ID No. 1905 Seq. ID No. 1906 949a Seq. ID No. 1907 Seq. ID No. 1908 949c Seq. ID No. 1911 Seq. ID No. 1912 949d Seq. ID No. 1913 Seq. ID No. 1914 950 Seq. ID No. 1915 Seq. ID No. 1916 951b Seq. ID No. 1919 Seq. ID No. 1920 952b Seq. ID No. 1923 Seq. ID No. 1924 954 Seq. ID No. 1925 Seq. ID No. 1926 955a Seq. ID No. 1927 Seq. ID No. 1928 955b Seq. ID No. 1929 Seq. ID No. 1930 956 Seq. ID No. 1931 Seq. ID No. 1932 958b Seq. ID No. 1935 Seq. ID No. 1936 961b Seq. ID No. 1941 Seq. ID No. 1942 961c Seq. ID No. 1943 Seq. ID No. 1944 963 Seq. ID No. 1945 Seq. ID No. 1946 965a Seq. ID No. 1947 Seq. ID No. 1948 965b Seq. ID No. 1949 Seq. ID No. 1950 966a Seq. ID No. 1951 Seq. ID No. 1952 966b Seq. ID No. 1953 Seq. ID No. 1954 968 Seq. ID No. 1959 Seq. ID No. 1960 969 Seq. ID No. 1961 Seq. ID No. 1962 972a Seq. ID No. 1963 Seq. ID No. 1964 972b Seq. ID No. 1965 Seq. ID No. 1966 976 Seq. ID No. 1967 Seq. ID No. 1968 977a Seq. ID No. 1969 Seq. ID No. 1970 977b Seq. ID No. 1971 Seq. ID No. 1972 980 Seq. ID No. 1979 Seq. ID No. 1980 982 Seq. ID No. 1983 Seq. ID No. 1984 984a Seq. ID No. 1985 Seq. ID No. 1986 984b Seq. ID No. 1987 Seq. ID No. 1988 986 Seq. ID No. 1989 Seq. ID No. 1990 987 Seq. ID No. 1991 Seq. ID No. 1992 988b Seq. ID No. 1995 Seq. ID No. 1996 988c Seq. ID No. 1997 Seq. ID No. 1998 988d Seq. ID No. 1999 Seq. ID No. 2000 991 Seq. ID No. 2001 Seq. ID No. 2002 992 Seq. ID No. 2003 Seq. ID No. 2004 993 Seq. ID No. 2005 Seq. ID No. 2006 994 Seq. ID No. 2007 Seq. ID No. 2008 998b Seq. ID No. 2015 Seq. ID No. 2016 999b Seq. ID No. 2019 Seq. ID No. 2020 1000 Seq. ID No. 2021 Seq. ID No. 2022 1003a Seq. ID No. 2025 Seq. ID No. 2026 1003b Seq. ID No. 2027 Seq. ID No. 2028 1004a Seq. ID No. 2029 Seq. ID No. 2030 1004b Seq. ID No. 2031 Seq. ID No. 2032 1006b Seq. ID No. 2035 Seq. ID No. 2036 1007 Seq. ID No. 2037 Seq. ID No. 2038 1013a Seq. ID No. 2041 Seq. 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ID No. 2916 1429b Seq. ID No. 2917 Seq. ID No. 2918 1431 Seq. ID No. 2919 Seq. ID No. 2920 1432 Seq. ID No. 2921 Seq. ID No. 2922 1433 Seq. ID No. 2923 Seq. ID No. 2924 1434b Seq. ID No. 2927 Seq. ID No. 2928 1437b Seq. ID No. 2931 Seq. ID No. 2932 1437c Seq. ID No. 2933 Seq. ID No. 2934 1438 Seq. ID No. 2935 Seq. ID No. 2936 1439d Seq. ID No. 2943 Seq. ID No. 2944 1439e Seq. ID No. 2945 Seq. ID No. 2946 1440c Seq. ID No. 2951 Seq. ID No. 2952 1440d Seq. ID No. 2953 Seq. ID No. 2954 1442b Seq. ID No. 2957 Seq. ID No. 2958 1445a Seq. ID No. 2959 Seq. ID No. 2960 1445b Seq. ID No. 2961 Seq. ID No. 2962 1445c Seq. ID No. 2963 Seq. ID No. 2964 1446a Seq. ID No. 2965 Seq. ID No. 2966 1446b Seq. ID No. 2967 Seq. ID No. 2968 1447b Seq. ID No. 2971 Seq. ID No. 2972 1448 Seq. ID No. 2973 Seq. ID No. 2974 1449a Seq. ID No. 2975 Seq. ID No. 2976 1449b Seq. ID No. 2977 Seq. ID No. 2978 1451 Seq. ID No. 2979 Seq. ID No. 2980 1452b Seq. ID No. 2983 Seq. ID No. 2984 1453 Seq. ID No. 2985 Seq. ID No. 2986 1454 Seq. ID No. 2987 Seq. ID No. 2988 1455b Seq. ID No. 2991 Seq. ID No. 2992 1456 Seq. ID No. 2993 Seq. ID No. 2994 1457c Seq. ID No. 2999 Seq. ID No. 3000 1459 Seq. ID No. 3001 Seq. ID No. 3002 1462b Seq. ID No. 3005 Seq. ID No. 3006 1463b Seq. ID No. 3009 Seq. ID No. 3010 1463c Seq. ID No. 3011 Seq. ID No. 3012 1466b Seq. ID No. 3015 Seq. ID No. 3016 1466c Seq. ID No. 3017 Seq. ID No. 3018 1466d Seq. ID No. 3019 Seq. ID No. 3020 1467 Seq. ID No. 3021 Seq. ID No. 3022 1469c Seq. ID No. 3027 Seq. ID No. 3028 1470c Seq. ID No. 3033 Seq. ID No. 3034 1471 Seq. ID No. 3035 Seq. ID No. 3036 1472b Seq. ID No. 3037 Seq. ID No. 3038 1472c Seq. ID No. 3039 Seq. ID No. 3040 1475 Seq. ID No. 3043 Seq. ID No. 3044 1476 Seq. ID No. 3045 Seq. ID No. 3046 1477a Seq. ID No. 3047 Seq. ID No. 3048 1477b Seq. ID No. 3049 Seq. ID No. 3050 1479a Seq. ID No. 3051 Seq. ID No. 3052 1479b Seq. ID No. 3053 Seq. ID No. 3054 1479c Seq. ID No. 3055 Seq. ID No. 3056 1482a Seq. ID No. 3057 Seq. ID No. 3058 1482b Seq. ID No. 3059 Seq. ID No. 3060 1484c Seq. ID No. 3067 Seq. ID No. 3068 1486 Seq. ID No. 3069 Seq. ID No. 3070 1487 Seq. ID No. 3071 Seq. ID No. 3072 1488d Seq. ID No. 3079 Seq. ID No. 3080 1488f Seq. ID No. 3083 Seq. ID No. 3084 1488g Seq. ID No. 3085 Seq. ID No. 3086 1489 Seq. ID No. 3087 Seq. ID No. 3088 1494 Seq. ID No. 3091 Seq. ID No. 3092 1497 Seq. ID No. 3093 Seq. ID No. 3094 1498c Seq. ID No. 3099 Seq. ID No. 3100 1498d Seq. ID No. 3101 Seq. ID No. 3102 1499 Seq. ID No. 3103 Seq. ID No. 3104 1503a Seq. ID No. 3109 Seq. ID No. 3110 1503b Seq. ID No. 3111 Seq. ID No. 3112 1506b Seq. ID No. 3115 Seq. ID No. 3116 1506c Seq. ID No. 3117 Seq. ID No. 3118 1507a Seq. ID No. 3119 Seq. ID No. 3120 1507b Seq. ID No. 3121 Seq. ID No. 3122 1507c Seq. ID No. 3123 Seq. ID No. 3124 1508 Seq. ID No. 3125 Seq. ID No. 3126 1510b Seq. ID No. 3129 Seq. ID No. 3130 1510c Seq. ID No. 3131 Seq. ID No. 3132 1510d Seq. ID No. 3133 Seq. ID No. 3134 1511 Seq. ID No. 3135 Seq. ID No. 3136 1512 Seq. ID No. 3137 Seq. ID No. 3138 1513a Seq. ID No. 3139 Seq. ID No. 3140 1513b Seq. ID No. 3141 Seq. ID No. 3142 1516 Seq. ID No. 3143 Seq. ID No. 3144 1517b Seq. ID No. 3147 Seq. ID No. 3148 1517c Seq. ID No. 3149 Seq. ID No. 3150 1518a Seq. ID No. 3151 Seq. ID No. 3152 1518b Seq. ID No. 3153 Seq. ID No. 3154 1520 Seq. ID No. 3155 Seq. ID No. 3156 1522 Seq. ID No. 3157 Seq. ID No. 3158 1523 Seq. ID No. 3159 Seq. ID No. 3160 1528 Seq. ID No. 3161 Seq. ID No. 3162 1530b Seq. ID No. 3165 Seq. ID No. 3166 1533a Seq. ID No. 3167 Seq. ID No. 3168 1534a Seq. ID No. 3169 Seq. ID No. 3170 1534b Seq. ID No. 3171 Seq. ID No. 3172 1535a Seq. ID No. 3173 Seq. ID No. 3174 1537 Seq. ID No. 3179 Seq. ID No. 3180 1542 Seq. ID No. 3181 Seq. ID No. 3182 1543 Seq. ID No. 3183 Seq. ID No. 3184 1544 Seq. ID No. 3185 Seq. ID No. 3186 1547a Seq. ID No. 3187 Seq. ID No. 3188 1547b Seq. ID No. 3189 Seq. ID No. 3190 1548 Seq. ID No. 3191 Seq. ID No. 3192 1552 Seq. ID No. 3193 Seq. ID No. 3194 1553a Seq. ID No. 3195 Seq. ID No. 3196 1553b Seq. ID No. 3197 Seq. ID No. 3198 1554c Seq. ID No. 3203 Seq. ID No. 3204 1555 Seq. ID No. 3205 Seq. ID No. 3206 1556a Seq. ID No. 3207 Seq. ID No. 3208 1556b Seq. ID No. 3209 Seq. ID No. 3210 1556c Seq. ID No. 3211 Seq. ID No. 3212 1557c Seq. ID No. 3217 Seq. ID No. 3218 1563 Seq. ID No. 3223 Seq. ID No. 3224 1564a Seq. ID No. 3225 Seq. ID No. 3226 1564b Seq. ID No. 3227 Seq. ID No. 3228 1565 Seq. ID No. 3229 Seq. ID No. 3230 1569 Seq. ID No. 3235 Seq. ID No. 3236 1572e Seq. ID No. 3249 Seq. ID No. 3250 1573 Seq. ID No. 3251 Seq. ID No. 3252 1576 Seq. ID No. 3253 Seq. ID No. 3254 1577a Seq. ID No. 3255 Seq. ID No. 3256 1577b Seq. ID No. 3257 Seq. ID No. 3258 1578 Seq. ID No. 3259 Seq. ID No. 3260 1580b Seq. ID No. 3263 Seq. ID No. 3264 1581 Seq. ID No. 3265 Seq. ID No. 3266 1582b Seq. ID No. 3269 Seq. ID No. 3270 1582c Seq. ID No. 3271 Seq. ID No. 3272 1584 Seq. ID No. 3273 Seq. ID No. 3274 1585b Seq. ID No. 3277 Seq. ID No. 3278 1587b Seq. ID No. 3281 Seq. ID No. 3282 1587c Seq. ID No. 3283 Seq. ID No. 3284 1588 Seq. ID No. 3285 Seq. ID No. 3286 1591 Seq. ID No. 3289 Seq. ID No. 3290 1592a Seq. ID No. 3291 Seq. ID No. 3292 159 b Seq. ID No. 3293 Seq. ID No. 3294 1594b Seq. ID No. 3299 Seq. ID No. 3300 1595a Seq. ID No. 3301 Seq. ID No. 3302 1595b Seq. ID No. 3303 Seq. ID No. 3304 1598a Seq. ID No. 3305 Seq. ID No. 3306 1598b Seq. ID No. 3307 Seq. ID No. 3308 1600a Seq. ID No. 3309 Seq. ID No. 3310 1600b Seq. ID No. 3311 Seq. ID No. 3312 1600c Seq. ID No. 3313 Seq. ID No. 3314 1602 Seq. ID No. 3315 Seq. ID No. 3316 1606b Seq. ID No. 3319 Seq. ID No. 3320 1607a Seq. ID No. 3321 Seq. ID No. 3322 1607b Seq. ID No. 3323 Seq. ID No. 3324 1608 Seq. ID No. 3325 Seq. ID No. 3326 1612 Seq. ID No. 3331 Seq. ID No. 3332 1616b Seq. ID No. 3335 Seq. ID No. 3336 1619 Seq. ID No. 3337 Seq. ID No. 3338 1621 Seq. ID No. 3339 Seq. ID No. 3340 1622a Seq. ID No. 3341 Seq. ID No. 3342 1623b Seq. ID No. 3345 Seq. ID No. 3346 1623c Seq. ID No. 3347 Seq. ID No. 3348 1624 Seq. ID No. 3349 Seq. ID No. 3350 1625b Seq. ID No. 3353 Seq. ID No. 3354 1625c Seq. ID No. 3355 Seq. ID No. 3356 1626b Seq. ID No. 3359 Seq. ID No. 3360 1628a Seq. ID No. 3361 Seq. ID No. 3362 1628b Seq. ID No. 3363 Seq. ID No. 3364 1632a Seq. ID No. 3365 Seq. ID No. 3366 1632b Seq. ID No. 3367 Seq. ID No. 3368 1633a Seq. ID No. 3369 Seq. ID No. 3370 1633b Seq. ID No. 3371 Seq. ID No. 3372 1634a Seq. ID No. 3373 Seq. ID No. 3374 1634b Seq. ID No. 3375 Seq. ID No. 3376 1634c Seq. ID No. 3377 Seq. ID No. 3378 1639b Seq. ID No. 3379 Seq. ID No. 3380 1642a Seq. ID No. 3381 Seq. ID No. 3382 1642b Seq. ID No. 3383 Seq. ID No. 3384 1646e Seq. ID No. 3397 Seq. ID No. 3398 1646f Seq. ID No. 3399 Seq. ID No. 3400 1647 Seq. ID No. 3401 Seq. ID No. 3402 1649b Seq. ID No. 3407 Seq. ID No. 3408 1649c Seq. ID No. 3409 Seq. ID No. 3410 1652b Seq. ID No. 3413 Seq. ID No. 3414 1654 Seq. ID No. 3415 Seq. ID No. 3416 1657 Seq. ID No. 3419 Seq. ID No. 3420 1659c Seq. ID No. 3425 Seq. ID No. 3426 1660b Seq. ID No. 3427 Seq. ID No. 3428 1662b Seq. ID No. 3431 Seq. ID No. 3432 1663 Seq. ID No. 3433 Seq. ID No. 3434 1664 Seq. ID No. 3435 Seq. ID No. 3436 1668 Seq. ID No. 3439 Seq. ID No. 3440 1669 Seq. ID No. 3441 Seq. ID No. 3442 1670a Seq. ID No. 3443 Seq. ID No. 3444 1670b Seq. ID No. 3445 Seq. ID No. 3446 1670c Seq. ID No. 3447 Seq. ID No. 3448 1673d Seq. ID No. 3455 Seq. ID No. 3456 1673e Seq. ID No. 3457 Seq. ID No. 3458 1673f Seq. ID No. 3459 Seq. ID No. 3460 1674 Seq. ID No. 3461 Seq. ID No. 3462 1675b Seq. ID No. 3465 Seq. ID No. 3466 1675c Seq. ID No. 3467 Seq. ID No. 3468 1677 Seq. ID No. 3471 Seq. ID No. 3472 1679 Seq. ID No. 3473 Seq. ID No. 3474 1680 Seq. ID No. 3475 Seq. ID No. 3476 1682b Seq. ID No. 3479 Seq. ID No. 3480 1683b Seq. ID No. 3483 Seq. ID No. 3484 1684 Seq. ID No. 3485 Seq. ID No. 3486 1685 Seq. ID No. 3487 Seq. ID No. 3488 1687 Seq. ID No. 3489 Seq. ID No. 3490 1688c Seq. ID No. 3495 Seq. ID No. 3496 1689a Seq. ID No. 3497 Seq. ID No. 3498 1689b Seq. ID No. 3499 Seq. ID No. 3500 1689c Seq. ID No. 3501 Seq. ID No. 3502 1690b Seq. ID No. 3505 Seq. ID No. 3506 1691 Seq. ID No. 3507 Seq. ID No. 3508 1692 Seq. ID No. 3509 Seq. ID No. 3510 1693 Seq. ID No. 3511 Seq. ID No. 3512 1694a Seq. ID No. 3513 Seq. ID No. 3514 1694c Seq. ID No. 3517 Seq. ID No. 3518 1694d Seq. ID No. 3519 Seq. ID No. 3520 1696 Seq. ID No. 3521 Seq. ID No. 3522 1697b Seq. ID No. 3525 Seq. ID No. 3526 1699b Seq. ID No. 3529 Seq. ID No. 3530 1700a Seq. ID No. 3531 Seq. ID No. 3532 1700b Seq. ID No. 3533 Seq. ID No. 3534 1701a Seq. ID No. 3535 Seq. ID No. 3536 1701b Seq. ID No. 3537 Seq. ID No. 3538 1703b Seq. ID No. 3539 Seq. ID No. 3540 1704a Seq. ID No. 3541 Seq. ID No. 3542 1704b Seq. ID No. 3543 Seq. ID No. 3544 1705a Seq. ID No. 3545 Seq. ID No. 3546 1705b Seq. ID No. 3547 Seq. ID No. 3548 1706 Seq. ID No. 3549 Seq. ID No. 3550 1707a Seq. ID No. 3551 Seq. ID No. 3552 1707b Seq. ID No. 3553 Seq. ID No. 3554 1708 Seq. ID No. 3555 Seq. ID No. 3556 1709 Seq. ID No. 3557 Seq. ID No. 3558 1710a Seq. ID No. 3559 Seq. ID No. 3560 1710b Seq. ID No. 3561 Seq. ID No. 3562 1712a Seq. ID No. 3563 Seq. ID No. 3564 1712b Seq. ID No. 3565 Seq. ID No. 3566 1715a Seq. ID No. 3567 Seq. ID No. 3568 1715b Seq. ID No. 3569 Seq. ID No. 3570 1718a Seq. ID No. 3571 Seq. ID No. 3572 1718b Seq. ID No. 3573 Seq. ID No. 3574 1722 Seq. ID No. 3575 Seq. ID No. 3576 1723b Seq. ID No. 3579 Seq. ID No. 3580 1724 Seq. ID No. 3581 Seq. ID No. 3582 1727 Seq. ID No. 3583 Seq. ID No. 3584 1731 Seq. ID No. 3587 Seq. ID No. 3588 1733 Seq. ID No. 3589 Seq. ID No. 3590 1735b Seq. ID No. 3595 Seq. ID No. 3596 1 737a Seq. ID No. 3597 Seq. ID No. 3598 1737b Seq. ID No. 3599 Seq. ID No. 3600 1738b Seq. ID No. 3603 Seq. ID No. 3604 1738c Seq. ID No. 3605 Seq. ID No. 3606 1739 Seq. ID No. 3607 Seq. ID No. 3608 1741 Seq. ID No. 3609 Seq. ID No. 3610 1743 Seq. ID No. 3611 Seq. ID No. 3612 1744a Seq. ID No. 3613 Seq. ID No. 3614 1744b Seq. ID No. 3615 Seq. ID No. 3616 1745 Seq. ID No. 3617 Seq. ID No. 3618 1747 Seq. ID No. 3619 Seq. ID No. 3620 1749a Seq. ID No. 3621 Seq. ID No. 3622 1749b Seq. ID No. 3623 Seq. ID No. 3624 1752a Seq. ID No. 3627 Seq. ID No. 3628 1752b Seq. ID No. 3629 Seq. ID No. 3630 1756b Seq. ID No. 3635 Seq. ID No. 3636 1757a Seq. ID No. 3637 Seq. ID No. 3638 1757b Seq. ID No. 3639 Seq. ID No. 3640 1759 Seq. ID No. 3641 Seq. ID No. 3642 1762 Seq. ID No. 3645 Seq. ID No. 3646 1764a Seq. ID No. 3647 Seq. ID No. 3648 1764b Seq. ID No. 3649 Seq. ID No. 3650 1764c Seq. ID No. 3651 Seq. ID No. 3652 1765 Seq. ID No. 3653 Seq. ID No. 3654 1767a Seq. ID No. 3657 Seq. ID No. 3658 1767b Seq. ID No. 3659 Seq. ID No. 3660 1769b Seq. ID No. 3663 Seq. ID No. 3664 1771 Seq. ID No. 3665 Seq. ID No. 3666 1773 Seq. ID No. 3667 Seq. ID No. 3668 1775a Seq. ID No. 3671 Seq. ID No. 3672 1775b Seq. ID No. 3673 Seq. ID No. 3674 1775c Seq. ID No. 3675 Seq. ID No. 3676 1778a Seq. ID No. 3677 Seq. ID No. 3678 1778b Seq. ID No. 3679 Seq. ID No. 3680 1780 Seq. ID No. 3681 Seq. ID No. 3682 1783a Seq. ID No. 3683 Seq. ID No. 3684 1783b Seq. ID No. 3685 Seq. ID No. 3686 1784a Seq. ID No. 3687 Seq. ID No. 3688 1784b Seq. ID No. 3689 Seq. ID No. 3690 1788a Seq. ID No. 3691 Seq. ID No. 3692 1788b Seq. ID No. 3693 Seq. ID No. 3694 1788c Seq. ID No. 3695 Seq. ID No. 3696 1789b Seq. ID No. 3699 Seq. ID No. 3700 1790a Seq. ID No. 3701 Seq. ID No. 3702 1790b Seq. ID No. 3703 Seq. ID No. 3704 1792a Seq. ID No. 3705 Seq. ID No. 3706 1792b Seq. ID No. 3707 Seq. ID No. 3708 1792c Seq. ID No. 3709 Seq. ID No. 3710 1793b Seq. ID No. 3713 Seq. ID No. 3714 1793c Seq. ID No. 3715 Seq. ID No. 3716 1794a Seq. ID No. 3717 Seq. ID No. 3718 1798c Seq. ID No. 3727 Seq. ID No. 3728 1800 Seq. ID No. 3729 Seq. ID No. 3730 1802b Seq. ID No. 3733 Seq. ID No. 3734 1804a Seq. ID No. 3737 Seq. ID No. 3738 1804b Seq. ID No. 3739 Seq. ID No. 3740 1805 Seq. ID No. 3741 Seq. ID No. 3742 1806b Seq. ID No. 3745 Seq. ID No. 3746 1806c Seq. ID No. 3747 Seq. ID No. 3748 1808d Seq. ID No. 3759 Seq. ID No. 3760 1809d Seq. ID No. 3767 Seq. ID No. 3768 1809e Seq. ID No. 3769 Seq. ID No. 3770 1809f Seq. ID No. 3771 Seq. ID No. 3772 1811b Seq. ID No. 3779 Seq. ID No. 3780 1812b Seq. ID No. 3783 Seq. ID No. 3784 1813 Seq. ID No. 3785 Seq. ID No. 3786 1815b Seq. ID No. 3789 Seq. ID No. 3790 1815c Seq. ID No. 3791 Seq. ID No. 3792 1816b Seq. ID No. 3795 Seq. ID No. 3796 1816c Seq. ID No. 3797 Seq. ID No. 3798 1819b Seq. ID No. 3803 Seq. ID No. 3804 1821 Seq. ID No. 3805 Seq. ID No. 3806 1822 Seq. ID No. 3807 Seq. ID No. 3808 1823a Seq. ID No. 3809 Seq. ID No. 3810 1823b Seq. ID No. 3811 Seq. ID No. 3812 1825 Seq. ID No. 3813 Seq. ID No. 3814 1826a Seq. ID No. 3815 Seq. ID No. 3816 1826b Seq. ID No. 3817 Seq. ID No. 3818 1828 Seq. ID No. 3819 Seq. ID No. 3820 1830b Seq. ID No. 3823 Seq. ID No. 3824 1833 Seq. ID No. 3825 Seq. ID No. 3826 1836a Seq. ID No. 3831 Seq. ID No. 3832 1836b Seq. ID No. 3833 Seq. ID No. 3834 1837 Seq. ID No. 3835 Seq. ID No. 3836 1838c Seq. ID No. 3841 Seq. ID No. 3842 1838d Seq. ID No. 3843 Seq. ID No. 3844 1839b Seq. ID No. 3847 Seq. ID No. 3848 1842d Seq. ID No. 3855 Seq. ID No. 3856 1843 Seq. ID No. 3857 Seq. ID No. 3858 1845c Seq. ID No. 3863 Seq. ID No. 3864 1848b Seq. ID No. 3867 Seq. ID No. 3868 1850b Seq. ID No. 3871 Seq. ID No. 3872 1850c Seq. ID No. 3873 Seq. ID No. 3874 1853a Seq. ID No. 3875 Seq. ID No. 3876 1853b Seq. ID No. 3877 Seq. ID No. 3878 1854b Seq. ID No. 3881 Seq. ID No. 3882 1855 Seq. ID No. 3883 Seq. ID No. 3884 1856 Seq. ID No. 3885 Seq. ID No. 3886 1857d Seq. ID No. 3893 Seq. ID No. 3894 1858 Seq. ID No. 3895 Seq. ID No. 3896 1861a Seq. ID No. 3899 Seq. ID No. 3900 1861b Seq. ID No. 3901 Seq. ID No. 3902 1863a Seq. ID No. 3905 Seq. ID No. 3906 1863b Seq. ID No. 3907 Seq. ID No. 3908 1865a Seq. ID No. 3911 Seq. ID No. 3912 1865b Seq. ID No. 3913 Seq. ID No. 3914 1868 Seq. ID No. 3915 Seq. ID No. 3916 1870 Seq. ID No. 3919 Seq. ID No. 3920 1873a Seq. ID No. 3921 Seq. ID No. 3922 1873b Seq. ID No. 3923 Seq. ID No. 3924 1873c Seq. ID No. 3925 Seq. ID No. 3926 1875b Seq. ID No. 3927 Seq. ID No. 3928 1875c Seq. ID No. 3929 Seq. ID No. 3930 1877a Seq. ID No. 3931 Seq. ID No. 3932 1877b Seq. ID No. 3933 Seq. ID No. 3934 1878 Seq. ID No. 3935 Seq. ID No. 3936 1882 Seq. ID No. 3939 Seq. ID No. 3940 1884 Seq. ID No. 3941 Seq. ID No. 3942 1886 Seq. ID No. 3943 Seq. ID No. 3944 1887 Seq. ID No. 3945 Seq. ID No. 3946 1888a Seq. ID No. 3947 Seq. ID No. 3948 1888b Seq. ID No. 3949 Seq. ID No. 3950 1890 Seq. ID No. 3951 Seq. ID No. 3952 1891a Seq. ID No. 3953 Seq. ID No. 3954 1891b Seq. ID No. 3955 Seq. ID No. 3956 1893 Seq. ID No. 3957 Seq. ID No. 3958 1894c Seq. ID No. 3959 Seq. ID No. 3960 1895 Seq. ID No. 3961 Seq. ID No. 3962 1896b Seq. ID No. 3965 Seq. ID No. 3966 1897a Seq. ID No. 3967 Seq. ID No. 3968 1897b Seq. ID No. 3969 Seq. ID No. 3970 1897c Seq. ID No. 3971 Seq. ID No. 3972 1898b Seq. ID No. 3975 Seq. ID No. 3976 1900 Seq. ID No. 3979 Seq. ID No. 3980 1902a Seq. ID No. 3981 Seq. ID No. 3982 1902b Seq. ID No. 3983 Seq. ID No. 3984 1907 Seq. ID No. 3985 Seq. ID No. 3986 1912 Seq. ID No. 3987 Seq. ID No. 3988 1915b Seq. ID No. 3991 Seq. ID No. 3992 1917a Seq. ID No. 3995 Seq. ID No. 3996 1917b Seq. ID No. 3997 Seq. ID No. 3998 1918b Seq. ID No. 3999 Seq. ID No. 4000 1918d Seq. ID No. 4003 Seq. ID No. 4004 1919b Seq. ID No. 4007 Seq. ID No. 4008 1919c Seq. ID No. 4009 Seq. ID No. 4010 1925 Seq. ID No. 4015 Seq. ID No. 4016 1926 Seq. ID No. 4017 Seq. ID No. 4018 1927b Seq. ID No. 4021 Seq. ID No. 4022 1930 Seq. ID No. 4023 Seq. ID No. 4024 1931c Seq. ID No. 4029 Seq. ID No. 4030 1933b Seq. ID No. 4035 Seq. ID No. 4036 1934 Seq. ID No. 4037 Seq. ID No. 4038 1936 Seq. ID No. 4039 Seq. ID No. 4040 1937e Seq. ID No. 4049 Seq. ID No. 4050 1939a Seq. ID No. 4051 Seq. ID No. 4052 1939b Seq. ID No. 4053 Seq. ID No. 4054 1939c Seq. ID No. 4055 Seq. ID No. 4056 1940 Seq. ID No. 4057 Seq. ID No. 4058 1941b Seq. ID No. 4061 Seq. ID No. 4062 1946c Seq. ID No. 4075 Seq. ID No. 4076 1950 Seq. ID No. 4079 Seq. ID No. 4080 1951c Seq. ID No. 4085 Seq. ID No. 4086 1951d Seq. ID No. 4087 Seq. ID No. 4088 1953 Seq. ID No. 4089 Seq. ID No. 4090 1954a Seq. ID No. 4091 Seq. ID No. 4092 1954b Seq. ID No. 4093 Seq. ID No. 4094 1954c Seq. ID No. 4095 Seq. ID No. 4096 1957 Seq. ID No. 4099 Seq. ID No. 4100 1958c Seq. ID No. 4105 Seq. ID No. 4106 1960a Seq. ID No. 4107 Seq. ID No. 4108 1960b Seq. ID No. 4109 Seq. ID No. 4110 1960c Seq. ID No. 4111 Seq. ID No. 4112 1961 Seq. ID No. 4113 Seq. ID No. 4114 1962b Seq. ID No. 4117 Seq. ID No. 4118 1965a Seq. ID No. 4119 Seq. ID No. 4120 1965b Seq. ID No. 4121 Seq. ID No. 4122 1966 Seq. ID No. 4123 Seq. ID No. 4124 1967 Seq. ID No. 4125 Seq. ID No. 4126 1968 Seq. ID No. 4127 Seq. ID No. 4128 1969 Seq. ID No. 4129 Seq. ID No. 4130 1970a Seq. ID No. 4131 Seq. ID No. 4132 1970b Seq. ID No. 4133 Seq. ID No. 4134 1972 Seq. ID No. 4135 Seq. ID No. 4136 1973 Seq. ID No. 4137 Seq. ID No. 4138 1976 Seq. ID No. 4139 Seq. ID No. 4140 1977a Seq. ID No. 4141 Seq. ID No. 4142 1977b Seq. ID No. 4143 Seq. ID No. 4144 1977c Seq. ID No. 4145 Seq. ID No. 4146 1979b Seq. ID No. 4149 Seq. ID No. 4150 1980b Seq. ID No. 4153 Seq. ID No. 4154 1981 Seq. ID No. 4155 Seq. ID No. 4156 1982 Seq. ID No. 4157 Seq. ID No. 4158 1985b Seq. ID No. 4161 Seq. ID No. 4162 1986 Seq. ID No. 4163 Seq. ID No. 4164 1987b Seq. ID No. 4167 Seq. ID No. 4168 1989b Seq. ID No. 4171 Seq. ID No. 4172 1989c Seq. ID No. 4173 Seq. ID No. 4174 1990a Seq. ID No. 4175 Seq. ID No. 4176 1990b Seq. ID No. 4177 Seq. ID No. 4178 1990c Seq. ID No. 4179 Seq. ID No. 4180 1991 Seq. ID No. 4181 Seq. ID No. 4182 1992b Seq. ID No. 4185 Seq. ID No. 4186 1993a Seq. ID No. 4187 Seq. ID No. 4188 1993b Seq. ID No. 4189 Seq. ID No. 4190 1993c Seq. ID No. 4191 Seq. ID No. 4192 1996 Seq. ID No. 4193 Seq. ID No. 4194 2000 Seq. ID No. 4195 Seq. ID No. 4196 2001 Seq. ID No. 4197 Seq. ID No. 4198 2003 Seq. ID No. 4199 Seq. ID No. 4200 2008 Seq. ID No. 4203 Seq. ID No. 4204 2010 Seq. ID No. 4205 Seq. ID No. 4206 2011a Seq. ID No. 4207 Seq. ID No. 4208 2011b Seq. ID No. 4209 Seq. ID No. 4210 2011c Seq. ID No. 4211 Seq. ID No. 4212 2015 Seq. ID No. 4219 Seq. ID No. 4220 2016e Seq. ID No. 4229 Seq. ID No. 4230 2016g Seq. ID No. 4233 Seq. ID No. 4234 2016h Seq. ID No. 4235 Seq. ID No. 4236 2020 Seq. ID No. 4237 Seq. ID No. 4238 2021 Seq. ID No. 4239 Seq. ID No. 4240 2023b Seq. ID No. 4243 Seq. ID No. 4244 2024c Seq. ID No. 4249 Seq. ID No. 4250 2024d Seq. ID No. 4251 Seq. ID No. 4252 2025 Seq. ID No. 4253 Seq. ID No. 4254 2027 Seq. ID No. 4255 Seq. ID No. 4256 2030b Seq. ID No. 4259 Seq. ID No. 4260 2030d Seq. ID No. 4263 Seq. ID No. 4264 2032c Seq. ID No. 4265 Seq. ID No. 4266 2033 Seq. ID No. 4267 Seq. ID No. 4268 2035b Seq. ID No. 4269 Seq. ID No. 4270 2036 Seq. ID No. 4271 Seq. ID No. 4272 2037 Seq. ID No. 4273 Seq. ID No. 4274 2038a Seq. ID No. 4275 Seq. ID No. 4276 2043b Seq. ID No. 4281 Seq. ID No. 4282 2044 Seq. ID No. 4283 Seq. ID No. 4284 2045a Seq. ID No. 4285 Seq. ID No. 4286 2045b Seq. ID No. 4287 Seq. ID No. 4288 2046a Seq. ID No. 4289 Seq. ID No. 4290 2046b Seq. ID No. 4291 Seq. ID No. 4292 2047a Seq. ID No. 4293 Seq. ID No. 4294 2047b Seq. ID No. 4295 Seq. ID No. 4296 2049c Seq. ID No. 4297 Seq. ID No. 4298 2050 Seq. ID No. 4299 Seq. ID No. 4300 2053 Seq. ID No. 4301 Seq. ID No. 4302 2054 Seq. ID No. 4303 Seq. ID No. 4304 2056 Seq. ID No. 4307 Seq. ID No. 4308 2057 Seq. ID No. 4309 Seq. ID No. 4310 2059b Seq. ID No. 4313 Seq. ID No. 4314 2060a Seq. ID No. 4315 Seq. ID No. 4316 2060b Seq. ID No. 4317 Seq. ID No. 4318 2062a Seq. ID No. 4319 Seq. ID No. 4320 2062b Seq. ID No. 4321 Seq. ID No. 4322 2062c Seq. ID No. 4323 Seq. ID No. 4324 2064 Seq. ID No. 4325 Seq. ID No. 4326 2065b Seq. ID No. 4329 Seq. ID No. 4330 2066 Seq. ID No. 4331 Seq. ID No. 4332 2068 Seq. ID No. 4333 Seq. ID No. 4334 2069a Seq. ID No. 4335 Seq. 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ID No. 4460 2129a #N/A #N/A 2129b #N/A #N/A 2133 Seq. ID No. 4461 Seq. ID No. 4462 2138b Seq. ID No. 4465 Seq. ID No. 4466 2138c Seq. ID No. 4467 Seq. ID No. 4468 2140b Seq. ID No. 4471 Seq. ID No. 4472 2142b Seq. ID No. 4475 Seq. ID No. 4476 2144a Seq. ID No. 4477 Seq. ID No. 4478 2144b Seq. ID No. 4479 Seq. ID No. 4480 2146 Seq. ID No. 4481 Seq. ID No. 4482 2147b Seq. ID No. 4485 Seq. ID No. 4486 2147c Seq. ID No. 4487 Seq. ID No. 4488 2149a Seq. ID No. 4489 Seq. ID No. 4490 2149b Seq. ID No. 4491 Seq. ID No. 4492 2150a Seq. ID No. 4493 Seq. ID No. 4494 2150b Seq. ID No. 4495 Seq. ID No. 4496 2150c Seq. ID No. 4497 Seq. ID No. 4498 2153 Seq. ID No. 4501 Seq. ID No. 4502 2155a Seq. ID No. 4503 Seq. ID No. 4504 2155b Seq. ID No. 4505 Seq. ID No. 4506 2156a Seq. ID No. 4507 Seq. ID No. 4508 2156b Seq. ID No. 4509 Seq. ID No. 4510 2156c Seq. ID No. 4511 Seq. ID No. 4512 2159a Seq. ID No. 4513 Seq. ID No. 4514 2159b Seq. ID No. 4515 Seq. ID No. 4516 2160b Seq. ID No. 4519 Seq. 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ID No. 4654 2225 Seq. ID No. 4659 Seq. ID No. 4660 2226 Seq. ID No. 4661 Seq. ID No. 4662 2227 Seq. ID No. 4663 Seq. ID No. 4664 2228a Seq. ID No. 4665 Seq. ID No. 4666 2228b Seq. ID No. 4667 Seq. ID No. 4668 2228c Seq. ID No. 4669 Seq. ID No. 4670 2231 Seq. ID No. 4671 Seq. ID No. 4672 2232 Seq. ID No. 4673 Seq. ID No. 4674 2234a Seq. ID No. 4675 Seq. ID No. 4676 2234b Seq. ID No. 4677 Seq. ID No. 4678 2234c Seq. ID No. 4679 Seq. ID No. 4680 2236b Seq. ID No. 4683 Seq. ID No. 4684 2238 Seq. ID No. 4685 Seq. ID No. 4686 2239b Seq. ID No. 4687 Seq. ID No. 4688 2240b Seq. ID No. 4691 Seq. ID No. 4692 2240c Seq. ID No. 4693 Seq. ID No. 4694 2243a Seq. ID No. 4695 Seq. ID No. 4696 2245 Seq. ID No. 4699 Seq. ID No. 4700 2246 Seq. ID No. 4701 Seq. ID No. 4702 2248 Seq. ID No. 4703 Seq. ID No. 4704 2249 Seq. ID No. 4705 Seq. ID No. 4706 2253d Seq. ID No. 4713 Seq. ID No. 4714 2255b Seq. ID No. 4717 Seq. ID No. 4718 2256 Seq. ID No. 4719 Seq. ID No. 4720 2257 Seq. ID No. 4721 Seq. 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ID No. 4792 2291a Seq. ID No. 4793 Seq. ID No. 4794 2291b Seq. ID No. 4795 Seq. ID No. 4796 2291c Seq. ID No. 4797 Seq. ID No. 4798 2292b Seq. ID No. 4801 Seq. ID No. 4802 2292c Seq. ID No. 4803 Seq. ID No. 4804 2294 Seq. ID No. 4805 Seq. ID No. 4806 2298 Seq. ID No. 4809 Seq. ID No. 4810 2299 Seq. ID No. 4811 Seq. ID No. 4812 2300 Seq. ID No. 4813 Seq. ID No. 4814 2301 Seq. ID No. 4815 Seq. ID No. 4816 2302 Seq. ID No. 4817 Seq. ID No. 4818 2303 Seq. ID No. 4819 Seq. ID No. 4820 2307 Seq. ID No. 4825 Seq. ID No. 4826 2308 Seq. ID No. 4827 Seq. ID No. 4828 2309a Seq. ID No. 4829 Seq. ID No. 4830 2309b Seq. ID No. 4831 Seq. ID No. 4832 2309c Seq. ID No. 4833 Seq. ID No. 4834 2311 Seq. ID No. 4837 Seq. ID No. 4838 2312a Seq. ID No. 4839 Seq. ID No. 4840 2312b Seq. ID No. 4841 Seq. ID No. 4842 2312c Seq. ID No. 4843 Seq. ID No. 4844 2314 Seq. ID No. 4845 Seq. ID No. 4846 2316 Seq. ID No. 4849 Seq. ID No. 4850 2317 Seq. ID No. 4851 Seq. ID No. 4852 2320 Seq. ID No. 4853 Seq. ID No. 4854 2321a Seq. ID No. 4855 Seq. ID No. 4856 2322 Seq. ID No. 4861 Seq. ID No. 4862 2324 Seq. ID No. 4863 Seq. ID No. 4864 2328 Seq. ID No. 4867 Seq. ID No. 4868 2329d Seq. ID No. 4875 Seq. ID No. 4876 2330 Seq. ID No. 4877 Seq. ID No. 4878 2331 Seq. ID No. 4879 Seq. ID No. 4880 2333 Seq. ID No. 4881 Seq. ID No. 4882 2335 Seq. ID No. 4883 Seq. ID No. 4884 2338a Seq. ID No. 4889 Seq. ID No. 4890 2338b Seq. ID No. 4891 Seq. ID No. 4892 2338c Seq. ID No. 4893 Seq. ID No. 4894 2342a Seq. ID No. 4895 Seq. ID No. 4896 2342b Seq. ID No. 4897 Seq. ID No. 4898 2342c Seq. ID No. 4899 Seq. ID No. 4900 2344 Seq. ID No. 4901 Seq. ID No. 4902 2345 Seq. ID No. 4903 Seq. ID No. 4904 2347 Seq. ID No. 4905 Seq. ID No. 4906 2348 Seq. ID No. 4907 Seq. ID No. 4908 2349a Seq. ID No. 4909 Seq. ID No. 4910 2349b Seq. ID No. 4911 Seq. ID No. 4912 2350a Seq. ID No. 4913 Seq. ID No. 4914 2353 Seq. ID No. 4915 Seq. ID No. 4916 2354 Seq. ID No. 4917 Seq. ID No. 4918 2357 Seq. ID No. 4919 Seq. ID No. 4920 2358 Seq. ID No. 4921 Seq. ID No. 4922 2360 Seq. ID No. 4923 Seq. ID No. 4924 2361b Seq. ID No. 4927 Seq. ID No. 4928 2363b Seq. ID No. 4931 Seq. ID No. 4932 2365b Seq. ID No. 4935 Seq. ID No. 4936 2366a Seq. ID No. 4937 Seq. ID No. 4938 2366b Seq. ID No. 4939 Seq. ID No. 4940 2367 Seq. ID No. 4941 Seq. ID No. 4942 2368 Seq. ID No. 4943 Seq. ID No. 4944 2369 Seq. ID No. 4945 Seq. ID No. 4946 2370 Seq. ID No. 4947 Seq. ID No. 4948 2371a Seq. ID No. 4949 Seq. ID No. 4950 2372 Seq. ID No. 4951 Seq. ID No. 4952 2373 Seq. ID No. 4953 Seq. ID No. 4954 2374b Seq. ID No. 4957 Seq. ID No. 4958 2376 Seq. ID No. 4959 Seq. ID No. 4960 2377a Seq. ID No. 4961 Seq. ID No. 4962 2377b Seq. ID No. 4963 Seq. ID No. 4964 2381 Seq. ID No. 4973 Seq. ID No. 4974 2382c Seq. ID No. 4975 Seq. ID No. 4976 2384a Seq. ID No. 4977 Seq. ID No. 4978 2384b Seq. ID No. 4979 Seq. ID No. 4980 2386b Seq. ID No. 4981 Seq. ID No. 4982 2386c Seq. ID No. 4983 Seq. ID No. 4984 2387 Seq. ID No. 4985 Seq. ID No. 4986 2390 Seq. ID No. 4987 Seq. ID No. 4988 2391 Seq. ID No. 4989 Seq. ID No. 4990 2392 Seq. ID No. 4991 Seq. ID No. 4992 2394 Seq. ID No. 4993 Seq. ID No. 4994 2395 Seq. ID No. 4995 Seq. ID No. 4996 2396 Seq. ID No. 4997 Seq. ID No. 4998 2397 Seq. ID No. 4999 Seq. ID No. 5000 2399a Seq. ID No. 5003 Seq. ID No. 5004 2399b Seq. ID No. 5005 Seq. ID No. 5006 2399c Seq. ID No. 5007 Seq. ID No. 5008 2401 Seq. ID No. 5009 Seq. ID No. 5010 2402a Seq. ID No. 5011 Seq. ID No. 5012 2402b Seq. ID No. 5013 Seq. ID No. 5014 2403b Seq. ID No. 5017 Seq. ID No. 5018 2404a Seq. ID No. 5019 Seq. ID No. 5020 2404b Seq. ID No. 5021 Seq. ID No. 5022 2407a Seq. ID No. 5023 Seq. ID No. 5024 2409a Seq. ID No. 5025 Seq. ID No. 5026 2410 Seq. ID No. 5029 Seq. ID No. 5030 2412 Seq. ID No. 5031 Seq. ID No. 5032 2413a Seq. ID No. 5033 Seq. ID No. 5034 2413b Seq. ID No. 5035 Seq. ID No. 5036 2416b Seq. ID No. 5041 Seq. ID No. 5042 2416c Seq. ID No. 5043 Seq. ID No. 5044 2417a Seq. ID No. 5045 Seq. ID No. 5046 2417b Seq. ID No. 5047 Seq. ID No. 5048 2422b Seq. ID No. 5057 Seq. ID No. 5058 2422c Seq. ID No. 5059 Seq. ID No. 5060 2423b Seq. ID No. 5063 Seq. ID No. 5064 2424a Seq. ID No. 5065 Seq. ID No. 5066 2424b Seq. ID No. 5067 Seq. ID No. 5068 2424c Seq. ID No. 5069 Seq. ID No. 5070 2428b Seq. ID No. 5075 Seq. ID No. 5076 2428c Seq. ID No. 5077 Seq. ID No. 5078 2429 Seq. ID No. 5079 Seq. ID No. 5080 2432 Seq. ID No. 5081 Seq. ID No. 5082 2433 Seq. ID No. 5083 Seq. ID No. 5084 2434 Seq. ID No. 5085 Seq. ID No. 5086 2440 Seq. ID No. 5087 Seq. ID No. 5088 2442b Seq. ID No. 5091 Seq. ID No. 5092 2444c Seq. ID No. 5099 Seq. ID No. 5100 2444d Seq. ID No. 5101 Seq. ID No. 5102 2445 Seq. ID No. 5103 Seq. ID No. 5104 2449b Seq. ID No. 5109 Seq. ID No. 5110 2451 Seq. ID No. 5111 Seq. ID No. 5112 2452 Seq. ID No. 5113 Seq. ID No. 5114 2453 Seq. ID No. 5115 Seq. ID No. 5116 2455 Seq. ID No. 5117 Seq. ID No. 5118 2456b Seq. ID No. 5121 Seq. ID No. 5122 2456d Seq. ID No. 5125 Seq. ID No. 5126 2456e Seq. ID No. 5127 Seq. ID No. 5128 2458c Seq. ID No. 5133 Seq. ID No. 5134 2458f Seq. ID No. 5139 Seq. ID No. 5140 2458g Seq. ID No. 5141 Seq. ID No. 5142 2461b Seq. ID No. 5145 Seq. ID No. 5146 2462a Seq. ID No. 5147 Seq. ID No. 5148 2462b Seq. ID No. 5149 Seq. ID No. 5150 2463a Seq. ID No. 5151 Seq. ID No. 5152 2465a Seq. ID No. 5155 Seq. ID No. 5156 2465b Seq. ID No. 5157 Seq. ID No. 5158 2468a Seq. ID No. 5159 Seq. ID No. 5160 2468b Seq. ID No. 5161 Seq. ID No. 5162 2469b Seq. ID No. 5165 Seq. ID No. 5166 2470 Seq. ID No. 5167 Seq. ID No. 5168 2471 Seq. ID No. 5169 Seq. ID No. 5170 2474c Seq. ID No. 5177 Seq. ID No. 5178 2475b Seq. ID No. 5181 Seq. ID No. 5182 2475c Seq. ID No. 5183 Seq. ID No. 5184 2477 Seq. ID No. 5185 Seq. ID No. 5186 2480 Seq. ID No. 5187 Seq. ID No. 5188 2481a Seq. ID No. 5189 Seq. ID No. 5190 2481b Seq. ID No. 5191 Seq. ID No. 5192 2482 Seq. ID No. 5193 Seq. ID No. 5194 2483 Seq. ID No. 5195 Seq. ID No. 5196 2484a Seq. ID No. 5197 Seq. ID No. 5198 2484b Seq. ID No. 5199 Seq. ID No. 5200 2485 Seq. ID No. 5201 Seq. ID No. 5202 2489 Seq. ID No. 5203 Seq. ID No. 5204 2490 Seq. ID No. 5205 Seq. ID No. 5206 2492b Seq. ID No. 5209 Seq. ID No. 5210 2494 Seq. ID No. 5211 Seq. ID No. 5212 2495b Seq. ID No. 5215 Seq. ID No. 5216 2497b Seq. ID No. 5219 Seq. ID No. 5220 2498b Seq. ID No. 5221 Seq. ID No. 5222 2501a Seq. ID No. 5229 Seq. ID No. 5230 2501b Seq. ID No. 5231 Seq. ID No. 5232 2506 Seq. ID No. 5239 Seq. ID No. 5240 2507b Seq. ID No. 5241 Seq. ID No. 5242 2507c Seq. ID No. 5243 Seq. ID No. 5244 2510 Seq. ID No. 5245 Seq. ID No. 5246 2513b Seq. ID No. 5251 Seq. ID No. 5252 2513c Seq. ID No. 5253 Seq. ID No. 5254 2514 Seq. ID No. 5255 Seq. ID No. 5256 2516b Seq. ID No. 5261 Seq. ID No. 5262 2517a Seq. ID No. 5263 Seq. ID No. 5264 2517b Seq. ID No. 5265 Seq. ID No. 5266 2518a Seq. ID No. 5267 Seq. ID No. 5268 2520c Seq. ID No. 5277 Seq. ID No. 5278 2520d Seq. ID No. 5279 Seq. ID No. 5280 2521 Seq. ID No. 5281 Seq. ID No. 5282 2525a Seq. ID No. 5285 Seq. ID No. 5286 2525b Seq. ID No. 5287 Seq. ID No. 5288 2527b Seq. ID No. 5291 Seq. ID No. 5292 2528b Seq. ID No. 5295 Seq. ID No. 5296 2528c Seq. ID No. 5297 Seq. ID No. 5298 2528d Seq. ID No. 5299 Seq. ID No. 5300 2532b Seq. ID No. 5301 Seq. ID No. 5302 2532c Seq. ID No. 5303 Seq. ID No. 5304 2534 Seq. ID No. 5305 Seq. ID No. 5306 2535a Seq. ID No. 5307 Seq. ID No. 5308 2535b Seq. ID No. 5309 Seq. ID No. 5310 2538 Seq. ID No. 5311 Seq. ID No. 5312 2541 Seq. ID No. 5313 Seq. ID No. 5314 2542b Seq. ID No. 5317 Seq. ID No. 5318 2542c Seq. ID No. 5319 Seq. ID No. 5320 2543 Seq. ID No. 5321 Seq. ID No. 5322 2544 Seq. ID No. 5323 Seq. ID No. 5324 2546 Seq. ID No. 5327 Seq. ID No. 5328 2547b Seq. ID No. 5329 Seq. ID No. 5330 2547c Seq. ID No. 5331 Seq. ID No. 5332 2548a Seq. ID No. 5333 Seq. ID No. 5334 2548b Seq. ID No. 5335 Seq. ID No. 5336 2549 Seq. ID No. 5337 Seq. ID No. 5338 2550e Seq. ID No. 5343 Seq. ID No. 5344 2552 Seq. ID No. 5345 Seq. ID No. 5346 2554a Seq. ID No. 5349 Seq. ID No. 5350 2554b Seq. ID No. 5351 Seq. ID No. 5352 2555c Seq. ID No. 5357 Seq. ID No. 5358 2555d Seq. ID No. 5359 Seq. ID No. 5360 2559 Seq. ID No. 5365 Seq. ID No. 5366 2561 Seq. ID No. 5367 Seq. ID No. 5368 2563 Seq. ID No. 5373 Seq. ID No. 5374 2564b Seq. ID No. 5377 Seq. ID No. 5378 2564c Seq. ID No. 5379 Seq. ID No. 5380 2564d Seq. ID No. 5381 Seq. ID No. 5382 2566 Seq. ID No. 5383 Seq. ID No. 5384 2567b Seq. ID No. 5387 Seq. ID No. 5388 2568 Seq. ID No. 5389 Seq. ID No. 5390 2572 Seq. ID No. 5391 Seq. ID No. 5392 2573 Seq. ID No. 5393 Seq. ID No. 5394 2576 Seq. ID No. 5397 Seq. ID No. 5398 2578 Seq. ID No. 5399 Seq. ID No. 5400 2579b Seq. ID No. 5401 Seq. ID No. 5402 2581 Seq. ID No. 5403 Seq. ID No. 5404 2582a Seq. ID No. 5405 Seq. ID No. 5406 2582b Seq. ID No. 5407 Seq. ID No. 5408 2582c Seq. ID No. 5409 Seq. ID No. 5410 2585 Seq. ID No. 5411 Seq. ID No. 5412 2587b Seq. ID No. 5415 Seq. ID No. 5416 2588 Seq. ID No. 5417 Seq. ID No. 5418 2589 Seq. ID No. 5419 Seq. ID No. 5420 2591 Seq. ID No. 5421 Seq. ID No. 5422 2592 Seq. ID No. 5423 Seq. ID No. 5424 2593a Seq. ID No. 5425 Seq. ID No. 5426 2593b Seq. ID No. 5427 Seq. ID No. 5428 2594b Seq. ID No. 5431 Seq. ID No. 5432 2596 Seq. ID No. 5433 Seq. ID No. 5434 2597a Seq. ID No. 5435 Seq. ID No. 5436 2597b Seq. ID No. 5437 Seq. ID No. 5438 2597c Seq. ID No. 5439 Seq. ID No. 5440 2598 Seq. ID No. 5441 Seq. ID No. 5442 2602 Seq. ID No. 5443 Seq. ID No. 5444 2605b Seq. ID No. 5447 Seq. ID No. 5448 2606 Seq. ID No. 5449 Seq. ID No. 5450 2608 Seq. ID No. 5451 Seq. ID No. 5452 2610 Seq. ID No. 5453 Seq. ID No. 5454 2611 Seq. ID No. 5455 Seq. ID No. 5456 2613 Seq. ID No. 5457 Seq. ID No. 5458 2616e Seq. ID No. 5467 Seq. ID No. 5468 2616g Seq. ID No. 5471 Seq. ID No. 5472 2616h Seq. ID No. 5473 Seq. ID No. 5474 2617b Seq. ID No. 5477 Seq. ID No. 5478 2618a Seq. ID No. 5479 Seq. ID No. 5480 2618b Seq. ID No. 5481 Seq. ID No. 5482 2623b Seq. ID No. 5491 Seq. ID No. 5492 2624a Seq. ID No. 5493 Seq. ID No. 5494 2624b Seq. ID No. 5495 Seq. ID No. 5496 2625b Seq. ID No. 5499 Seq. ID No. 5500 2626b Seq. ID No. 5503 Seq. ID No. 5504 2628 Seq. ID No. 5509 Seq. ID No. 5510 2629b Seq. ID No. 5513 Seq. ID No. 5514 2631 Seq. ID No. 5515 Seq. ID No. 5516 2632 Seq. ID No. 5517 Seq. ID No. 5518 2633a Seq. ID No. 5519 Seq. ID No. 5520 2633b Seq. ID No. 5521 Seq. ID No. 5522 2633e Seq. ID No. 5527 Seq. ID No. 5528 2637a Seq. ID No. 5529 Seq. ID No. 5530 2637b Seq. ID No. 5531 Seq. ID No. 5532 2642 Seq. ID No. 5533 Seq. ID No. 5534 2643b Seq. ID No. 5537 Seq. ID No. 5538 2645 Seq. ID No. 5539 Seq. ID No. 5540 2647 Seq. ID No. 5541 Seq. ID No. 5542 2648a Seq. ID No. 5543 Seq. ID No. 5544 2648b Seq. ID No. 5545 Seq. ID No. 5546 2649 Seq. ID No. 5547 Seq. ID No. 5548 2650 Seq. ID No. 5549 Seq. ID No. 5550 2652a Seq. ID No. 5551 Seq. ID No. 5552 2652b Seq. ID No. 5553 Seq. ID No. 5554 2655b Seq. ID No. 5557 Seq. ID No. 5558 2656 Seq. ID No. 5559 Seq. ID No. 5560 2658b Seq. ID No. 5563 Seq. ID No. 5564 2659b Seq. ID No. 5567 Seq. ID No. 5568 2660 Seq. ID No. 5569 Seq. ID No. 5570 2664b Seq. ID No. 5575 Seq. ID No. 5576 2665 Seq. ID No. 5577 Seq. ID No. 5578 2666b Seq. ID No. 5581 Seq. ID No. 5582 2667a Seq. ID No. 5583 Seq. ID No. 5584 2667b Seq. ID No. 5585 Seq. ID No. 5586 2669b Seq. ID No. 5589 Seq. ID No. 5590 2669c Seq. ID No. 5591 Seq. ID No. 5592 2672 Seq. ID No. 5593 Seq. ID No. 5594 2673 Seq. ID No. 5595 Seq. ID No. 5596 2674b Seq. ID No. 5599 Seq. ID No. 5600 2676 Seq. ID No. 5601 Seq. ID No. 5602 2677c Seq. ID No. 5607 Seq. ID No. 5608 2679c Seq. ID No. 5613 Seq. ID No. 5614 2679d Seq. ID No. 5615 Seq. ID No. 5616 2680a Seq. ID No. 5617 Seq. ID No. 5618 2680b Seq. ID No. 5619 Seq. ID No. 5620 2680c Seq. ID No. 5621 Seq. ID No. 5622 2683b Seq. ID No. 5625 Seq. ID No. 5626 2684a Seq. ID No. 5627 Seq. ID No. 5628 2684b Seq. ID No. 5629 Seq. ID No. 5630 2686 Seq. ID No. 5631 Seq. ID No. 5632 2688c Seq. ID No. 5637 Seq. ID No. 5638 2689a Seq. ID No. 5639 Seq. ID No. 5640 2689b Seq. ID No. 5641 Seq. ID No. 5642 2690b Seq. ID No. 5645 Seq. ID No. 5646 2690c Seq. ID No. 5647 Seq. ID No. 5648 2692b Seq. ID No. 5649 Seq. ID No. 5650 2693 Seq. ID No. 5651 Seq. ID No. 5652 2694b Seq. ID No. 5655 Seq. ID No. 5656 2695 Seq. ID No. 5657 Seq. ID No. 5658 2696b Seq. ID No. 5661 Seq. ID No. 5662 2709 Seq. ID No. 5665 Seq. ID No. 5666 2710c Seq. ID No. 5667 Seq. ID No. 5668 2712 Seq. ID No. 5669 Seq. ID No. 5670 2716b Seq. ID No. 5677 Seq. ID No. 5678 2716c Seq. ID No. 5679 Seq. ID No. 5680 2718b Seq. ID No. 5683 Seq. ID No. 5684 2718c Seq. ID No. 5685 Seq. ID No. 5686 2719a Seq. ID No. 5687 Seq. ID No. 5688 2719b Seq. ID No. 5689 Seq. ID No. 5690 2721a Seq. ID No. 5691 Seq. ID No. 5692 2721b Seq. ID No. 5693 Seq. ID No. 5694 2722b Seq. ID No. 5697 Seq. ID No. 5698 2723 Seq. ID No. 5699 Seq. ID No. 5700 2724 Seq. ID No. 5701 Seq. ID No. 5702 2725a Seq. ID No. 5703 Seq. ID No. 5704 2725b Seq. ID No. 5705 Seq. ID No. 5706 2726 Seq. ID No. 5707 Seq. ID No. 5708 2728b Seq. ID No. 5711 Seq. ID No. 5712 2731a Seq. ID No. 5713 Seq. ID No. 5714 2731b Seq. ID No. 5715 Seq. ID No. 5716 2732 Seq. ID No. 5717 Seq. ID No. 5718 2734a Seq. ID No. 5719 Seq. ID No. 5720 2734b Seq. ID No. 5721 Seq. ID No. 5722 2734c Seq. ID No. 5723 Seq. ID No. 5724 2735a Seq. ID No. 5725 Seq. ID No. 5726 2735b Seq. ID No. 5727 Seq. ID No. 5728 2738d Seq. ID No. 5735 Seq. ID No. 5736 2742b Seq. ID No. 5739 Seq. ID No. 5740 2743a Seq. ID No. 5741 Seq. ID No. 5742 2743b Seq. ID No. 5743 Seq. ID No. 5744 2744 Seq. ID No. 5745 Seq. ID No. 5746 2745a Seq. ID No. 5747 Seq. ID No. 5748 2745b Seq. ID No. 5749 Seq. ID No. 5750 2746 Seq. ID No. 5751 Seq. ID No. 5752 2747a Seq. ID No. 5753 Seq. ID No. 5754 2747b Seq. ID No. 5755 Seq. ID No. 5756 2748a Seq. ID No. 5757 Seq. ID No. 5758 2748b Seq. ID No. 5759 Seq. ID No. 5760 2748c Seq. ID No. 5761 Seq. ID No. 5762 2749d Seq. ID No. 5769 Seq. ID No. 5770 2749e Seq. ID No. 5771 Seq. ID No. 5772 2752 Seq. ID No. 5777 Seq. ID No. 5778 2753 Seq. ID No. 5779 Seq. ID No. 5780 2757b Seq. ID No. 5783 Seq. ID No. 5784 2758b Seq. ID No. 5787 Seq. ID No. 5788 2758d Seq. ID No. 5791 Seq. ID No. 5792 2759b Seq. ID No. 5795 Seq. ID No. 5796 2760b Seq. ID No. 5799 Seq. ID No. 5800 2760c Seq. ID No. 5801 Seq. ID No. 5802 2763b Seq. ID No. 5807 Seq. ID No. 5808 2763c Seq. ID No. 5809 Seq. ID No. 5810 2765b Seq. ID No. 5813 Seq. ID No. 5814 2765c Seq. ID No. 5815 Seq. ID No. 5816 2766b Seq. ID No. 5819 Seq. ID No. 5820 2768a Seq. ID No. 5821 Seq. ID No. 5822 2768b Seq. ID No. 5823 Seq. ID No. 5824 2768c Seq. ID No. 5825 Seq. ID No. 5826 2769a Seq. ID No. 5827 Seq. ID No. 5828 2770 Seq. ID No. 5829 Seq. ID No. 5830 2771a Seq. ID No. 5831 Seq. ID No. 5832 2771b Seq. ID No. 5833 Seq. ID No. 5834 2773 Seq. ID No. 5835 Seq. ID No. 5836 2774a Seq. ID No. 5837 Seq. ID No. 5838 2774b Seq. ID No. 5839 Seq. ID No. 5840 2774c Seq. ID No. 5841 Seq. ID No. 5842 2776b Seq. ID No. 5845 Seq. ID No. 5846 2777 Seq. ID No. 5847 Seq. ID No. 5848 2778 Seq. ID No. 5849 Seq. ID No. 5850 2779 Seq. ID No. 5851 Seq. ID No. 5852 2784 Seq. ID No. 5855 Seq. ID No. 5856 2785a Seq. ID No. 5857 Seq. ID No. 5858 2785b Seq. ID No. 5859 Seq. ID No. 5860 2786a Seq. ID No. 5861 Seq. ID No. 5862 2786b Seq. ID No. 5863 Seq. ID No. 5864 2786c Seq. ID No. 5865 Seq. ID No. 5866 2787b Seq. ID No. 5869 Seq. ID No. 5870 2787c Seq. ID No. 5871 Seq. ID No. 5872 2788b Seq. ID No. 5873 Seq. ID No. 5874 2789 Seq. ID No. 5875 Seq. ID No. 5876 2791 Seq. ID No. 5879 Seq. ID No. 5880 2793 Seq. ID No. 5881 Seq. ID No. 5882 2794 Seq. ID No. 5883 Seq. ID No. 5884 2799a Seq. ID No. 5889 Seq. ID No. 5890 2801b Seq. ID No. 5895 Seq. ID No. 5896 2804 Seq. ID No. 5897 Seq. ID No. 5898 2805b Seq. ID No. 5901 Seq. ID No. 5902 2809 Seq. ID No. 5903 Seq. ID No. 5904 2810d Seq. ID No. 5911 Seq. ID No. 5912 2812 Seq. ID No. 5913 Seq. ID No. 5914 2814 Seq. ID No. 5915 Seq. ID No. 5916 2815 Seq. ID No. 5917 Seq. ID No. 5918 2816 Seq. ID No. 5919 Seq. ID No. 5920 2818d Seq. ID No. 5927 Seq. ID No. 5928 2818e Seq. ID No. 5929 Seq. ID No. 5930 2820 Seq. ID No. 5933 Seq. ID No. 5934 2821a Seq. ID No. 5935 Seq. ID No. 5936 2821b Seq. ID No. 5937 Seq. ID No. 5938 2822b Seq. ID No. 5941 Seq. ID No. 5942 2824a Seq. ID No. 5945 Seq. ID No. 5946 2824b Seq. ID No. 5947 Seq. ID No. 5948 2829b Seq. ID No. 5951 Seq. ID No. 5952 2834a Seq. ID No. 5959 Seq. ID No. 5960 2834b Seq. ID No. 5961 Seq. ID No. 5962 2837a Seq. ID No. 5963 Seq. ID No. 5964 2837b Seq. ID No. 5965 Seq. ID No. 5966 2842a Seq. ID No. 5967 Seq. ID No. 5968 2842b Seq. ID No. 5969 Seq. ID No. 5970 2843a Seq. ID No. 5971 Seq. ID No. 5972 2843b Seq. ID No. 5973 Seq. ID No. 5974 2846a Seq. ID No. 5977 Seq. ID No. 5978 2846b Seq. ID No. 5979 Seq. ID No. 5980 2848 Seq. ID No. 5981 Seq. ID No. 5982 2851 Seq. ID No. 5985 Seq. ID No. 5986 2852 Seq. ID No. 5987 Seq. ID No. 5988 2853 Seq. ID No. 5989 Seq. ID No. 5990 2854a Seq. ID No. 5991 Seq. ID No. 5992 2854b Seq. ID No. 5993 Seq. ID No. 5994 2855 Seq. ID No. 5995 Seq. ID No. 5996 2856b Seq. ID No. 5999 Seq. ID No. 6000 2856c Seq. ID No. 6001 Seq. ID No. 6002 2857 Seq. ID No. 6003 Seq. ID No. 6004 2860b Seq. ID No. 6009 Seq. ID No. 6010 2860c Seq. ID No. 6011 Seq. ID No. 6012 2862 Seq. ID No. 6013 Seq. ID No. 6014 2863 Seq. ID No. 6015 Seq. ID No. 6016 2864 Seq. ID No. 6017 Seq. ID No. 6018 2869b Seq. ID No. 6025 Seq. ID No. 6026 2869c Seq. ID No. 6027 Seq. ID No. 6028 2871 Seq. ID No. 6029 Seq. ID No. 6030 2872 Seq. ID No. 6031 Seq. ID No. 6032 2875 Seq. ID No. 6033 Seq. ID No. 6034 2877 Seq. ID No. 6035 Seq. ID No. 6036 2879b Seq. ID No. 6039 Seq. ID No. 6040 2879c Seq. ID No. 6041 Seq. ID No. 6042 2881 Seq. ID No. 6043 Seq. ID No. 6044 2882 Seq. ID No. 6045 Seq. ID No. 6046 2883b Seq. ID No. 6049 Seq. ID No. 6050 2883c Seq. ID No. 6051 Seq. ID No. 6052 2883d Seq. ID No. 6053 Seq. ID No. 6054 2886a Seq. ID No. 6055 Seq. ID No. 6056 2886b Seq. ID No. 6057 Seq. ID No. 6058 2887b Seq. ID No. 6061 Seq. ID No. 6062 2888 Seq. ID No. 6063 Seq. ID No. 6064 2890 Seq. ID No. 6065 Seq. ID No. 6066 2891b Seq. ID No. 6069 Seq. ID No. 6070 2891c Seq. ID No. 6071 Seq. ID No. 6072 2893b Seq. ID No. 6073 Seq. ID No. 6074 2894b Seq. ID No. 6077 Seq. ID No. 6078 2894c Seq. ID No. 6079 Seq. ID No. 6080 2897b Seq. ID No. 6085 Seq. ID No. 6086 2900a Seq. ID No. 6087 Seq. ID No. 6088 2900b Seq. ID No. 6089 Seq. ID No. 6090 2901b Seq. ID No. 6093 Seq. ID No. 6094 2902 Seq. ID No. 6095 Seq. ID No. 6096 2905b Seq. ID No. 6101 Seq. ID No. 6102 2906 Seq. ID No. 6103 Seq. ID No. 6104 2909c Seq. ID No. 6109 Seq. ID No. 6110 2909d Seq. ID No. 6111 Seq. ID No. 6112 2913b Seq. ID No. 6117 Seq. ID No. 6118 2915b Seq. ID No. 6121 Seq. ID No. 6122 2915c Seq. ID No. 6123 Seq. ID No. 6124 2918 Seq. ID No. 6129 Seq. ID No. 6130 2920 Seq. ID No. 6131 Seq. ID No. 6132 2921 Seq. ID No. 6133 Seq. ID No. 6134 2922b Seq. ID No. 6135 Seq. ID No. 6136 2923a Seq. ID No. 6137 Seq. ID No. 6138 2923b Seq. ID No. 6139 Seq. ID No. 6140 2923c Seq. ID No. 6141 Seq. ID No. 6142 2925b Seq. ID No. 6145 Seq. ID No. 6146 2926c Seq. ID No. 6151 Seq. ID No. 6152 2928b Seq. ID No. 6155 Seq. ID No. 6156 2928c Seq. ID No. 6157 Seq. ID No. 6158 2929b Seq. ID No. 6159 Seq. ID No. 6160 2931c Seq. ID No. 6165 Seq. ID No. 6166 2933a Seq. ID No. 6167 Seq. ID No. 6168 2933b Seq. ID No. 6169 Seq. ID No. 6170 2934 Seq. ID No. 6171 Seq. ID No. 6172 2935b Seq. ID No. 6175 Seq. ID No. 6176 2936 Seq. ID No. 6177 Seq. ID No. 6178 2939b Seq. ID No. 6181 Seq. ID No. 6182 2941c Seq. ID No. 6187 Seq. ID No. 6188 2943c Seq. ID No. 6193 Seq. ID No. 6194 2943d Seq. ID No. 6195 Seq. ID No. 6196 2944b Seq. ID No. 6197 Seq. ID No. 6198 2945b Seq. ID No. 6199 Seq. ID No. 6200 2947 Seq. ID No. 6201 Seq. ID No. 6202 2948d Seq. ID No. 6209 Seq. ID No. 6210 2950b Seq. ID No. 6213 Seq. ID No. 6214 2951 Seq. ID No. 6215 Seq. ID No. 6216 2952 Seq. ID No. 6217 Seq. ID No. 6218 2954 Seq. ID No. 6219 Seq. ID No. 6220 2955f Seq. ID No. 6231 Seq. ID No. 6232 2955g Seq. ID No. 6233 Seq. ID No. 6234 2957 Seq. ID No. 6235 Seq. ID No. 6236 2958b Seq. ID No. 6239 Seq. ID No. 6240 2958c Seq. ID No. 6241 Seq. ID No. 6242 2959 Seq. ID No. 6243 Seq. ID No. 6244 2962b Seq. ID No. 6249 Seq. ID No. 6250 2965c Seq. ID No. 6257 Seq. ID No. 6258 2966 Seq. ID No. 6259 Seq. ID No. 6260 2967 Seq. ID No. 6261 Seq. ID No. 6262 2969 Seq. ID No. 6263 Seq. ID No. 6264 2970b Seq. ID No. 6267 Seq. ID No. 6268 2971a Seq. ID No. 6269 Seq. ID No. 6270 2971b Seq. ID No. 6271 Seq. ID No. 6272 2974b Seq. ID No. 6275 Seq. ID No. 6276 2975 Seq. ID No. 6277 Seq. ID No. 6278 2977a Seq. ID No. 6279 Seq. ID No. 6280 2977b Seq. ID No. 6281 Seq. ID No. 6282 2978a Seq. ID No. 6283 Seq. ID No. 6284 2978b Seq. ID No. 6285 Seq. ID No. 6286 2979 Seq. ID No. 6287 Seq. ID No. 6288 2980c Seq. ID No. 6293 Seq. ID No. 6294 2980d Seq. ID No. 6295 Seq. ID No. 6296 2980e Seq. ID No. 6297 Seq. ID No. 6298 2984 Seq. ID No. 6299 Seq. ID No. 6300 2986c Seq. ID No. 6305 Seq. ID No. 6306 2988b Seq. ID No. 6309 Seq. ID No. 6310 2988c Seq. ID No. 6311 Seq. ID No. 6312 2990 Seq. ID No. 6315 Seq. ID No. 6316 2991a Seq. ID No. 6317 Seq. ID No. 6318 2991b Seq. ID No. 6319 Seq. ID No. 6320 2991c Seq. ID No. 6321 Seq. ID No. 6322 2992 Seq. ID No. 6323 Seq. ID No. 6324 2993a Seq. ID No. 6325 Seq. ID No. 6326 2993b Seq. ID No. 6327 Seq. ID No. 6328 2995a Seq. ID No. 6329 Seq. ID No. 6330 2995b Seq. ID No. 6331 Seq. ID No. 6332 2998a Seq. ID No. 6335 Seq. ID No. 6336 2998b Seq. ID No. 6337 Seq. ID No. 6338 3001 Seq. ID No. 6341 Seq. ID No. 6342 3005 Seq. ID No. 6345 Seq. ID No. 6346 3008b Seq. ID No. 6349 Seq. ID No. 6350 3008c Seq. ID No. 6351 Seq. ID No. 6352 3008d Seq. ID No. 6353 Seq. ID No. 6354 3012 Seq. ID No. 6359 Seq. ID No. 6360 3015 Seq. ID No. 6361 Seq. ID No. 6362 3016c Seq. ID No. 6367 Seq. ID No. 6368 3017 Seq. ID No. 6369 Seq. ID No. 6370 3018a Seq. ID No. 6371 Seq. ID No. 6372 3018b Seq. ID No. 6373 Seq. ID No. 6374 3020 Seq. ID No. 6375 Seq. ID No. 6376 3021 Seq. ID No. 6377 Seq. ID No. 6378 3022 Seq. ID No. 6379 Seq. ID No. 6380 3023 Seq. ID No. 6381 Seq. ID No. 6382 3024b Seq. ID No. 6385 Seq. ID No. 6386 3026b Seq. ID No. 6389 Seq. ID No. 6390 3028b Seq. ID No. 6393 Seq. ID No. 6394 3028c Seq. ID No. 6395 Seq. ID No. 6396 3029b Seq. ID No. 6399 Seq. ID No. 6400 3033a Seq. ID No. 6409 Seq. ID No. 6410 3033b Seq. ID No. 6411 Seq. ID No. 6412 3035 Seq. ID No. 6413 Seq. ID No. 6414 3037b Seq. ID No. 6417 Seq. ID No. 6418 3040a Seq. ID No. 6421 Seq. ID No. 6422 3040b Seq. ID No. 6423 Seq. ID No. 6424 3042a Seq. ID No. 6425 Seq. ID No. 6426 3042b Seq. ID No. 6427 Seq. ID No. 6428 3043a Seq. ID No. 6429 Seq. ID No. 6430 3043b Seq. ID No. 6431 Seq. ID No. 6432 3049a Seq. ID No. 6441 Seq. ID No. 6442 3049b Seq. ID No. 6443 Seq. ID No. 6444 3049c Seq. ID No. 6445 Seq. ID No. 6446 3052 Seq. ID No. 6451 Seq. ID No. 6452 3054 Seq. ID No. 6453 Seq. ID No. 6454 3057 Seq. ID No. 6459 Seq. ID No. 6460 3059 Seq. ID No. 6461 Seq. ID No. 6462 3060 Seq. ID No. 6463 Seq. ID No. 6464 3061 Seq. ID No. 6465 Seq. ID No. 6466 3062 Seq. ID No. 6467 Seq. ID No. 6468 3063a Seq. ID No. 6469 Seq. ID No. 6470 3063b Seq. ID No. 6471 Seq. ID No. 6472 3064b Seq. ID No. 6473 Seq. ID No. 6474 3066 Seq. ID No. 6479 Seq. ID No. 6480 3068 Seq. ID No. 6483 Seq. ID No. 6484 3074 Seq. ID No. 6493 Seq. ID No. 6494 3075 Seq. ID No. 6495 Seq. ID No. 6496 3076 Seq. ID No. 6497 Seq. ID No. 6498 3077b Seq. ID No. 6501 Seq. ID No. 6502 3077c Seq. ID No. 6503 Seq. ID No. 6504 3078 Seq. ID No. 6505 Seq. ID No. 6506 3079 Seq. ID No. 6507 Seq. ID No. 6508 3081b Seq. ID No. 6511 Seq. ID No. 6512 3085 Seq. ID No. 6517 Seq. ID No. 6518 3087c Seq. ID No. 6523 Seq. ID No. 6524 3088 Seq. ID No. 6525 Seq. ID No. 6526 3092a Seq. ID No. 6535 Seq. ID No. 6536 3092b Seq. ID No. 6537 Seq. ID No. 6538 3095 Seq. ID No. 6539 Seq. ID No. 6540 3096a Seq. ID No. 6541 Seq. ID No. 6542 3096b Seq. ID No. 6543 Seq. ID No. 6544 3097 Seq. ID No. 6545 Seq. ID No. 6546 3098a Seq. ID No. 6547 Seq. ID No. 6548 3098b Seq. ID No. 6549 Seq. ID No. 6550 3098c Seq. ID No. 6551 Seq. ID No. 6552 3099 Seq. ID No. 6553 Seq. ID No. 6554 3100a Seq. ID No. 6555 Seq. ID No. 6556 3100b Seq. ID No. 6557 Seq. ID No. 6558 3101 Seq. ID No. 6559 Seq. ID No. 6560 3103b Seq. ID No. 6563 Seq. ID No. 6564 3107b Seq. ID No. 6573 Seq. ID No. 6574 3108a Seq. ID No. 6575 Seq. ID No. 6576 3108b Seq. ID No. 6577 Seq. ID No. 6578 3109 Seq. ID No. 6579 Seq. ID No. 6580 3110b Seq. ID No. 6583 Seq. ID No. 6584 3113 Seq. ID No. 6585 Seq. ID No. 6586 3116 Seq. ID No. 6587 Seq. ID No. 6588 3118b Seq. ID No. 6591 Seq. ID No. 6592 3119c Seq. ID No. 6597 Seq. ID No. 6598 3119e Seq. ID No. 6601 Seq. ID No. 6602 3119f Seq. ID No. 6603 Seq. ID No. 6604 3121 Seq. ID No. 6605 Seq. ID No. 6606 3122b Seq. ID No. 6609 Seq. ID No. 6610 3123a Seq. ID No. 6611 Seq. ID No. 6612 3123b Seq. ID No. 6613 Seq. ID No. 6614 3124 Seq. ID No. 6615 Seq. ID No. 6616 3126 Seq. ID No. 6617 Seq. ID No. 6618 3129a Seq. ID No. 6619 Seq. ID No. 6620 3129b Seq. ID No. 6621 Seq. ID No. 6622 3131 Seq. ID No. 6623 Seq. ID No. 6624 3134b Seq. ID No. 6627 Seq. ID No. 6628 3138 Seq. ID No. 6629 Seq. ID No. 6630 3140 Seq. ID No. 6631 Seq. ID No. 6632 3141 Seq. ID No. 6633 Seq. ID No. 6634 3145b Seq. ID No. 6637 Seq. ID No. 6638 3145c Seq. ID No. 6639 Seq. ID No. 6640 3147b Seq. ID No. 6643 Seq. ID No. 6644 3147c Seq. ID No. 6645 Seq. ID No. 6646 3150a Seq. ID No. 6649 Seq. ID No. 6650

Listed in Table 21, are 615 ORFs detected by another ORF finder program (Signal Search) of Applicant's assignee that searches for transmembrane regions between two Stop codons and a Start codon immediately upstream of the transmembrane region. TABLE 21 SIGNAL SEARCH ORFS ORF Number DNA SEQ ID Number Protein SEQ ID Number   4a Seq. ID No. 7 Seq. ID No. 8   4b Seq. ID No. 9 Seq. ID No. 10  23a Seq. ID No. 33 Seq. ID No. 34  38b Seq. ID No. 47 Seq. ID No. 48  44b Seq. ID No. 67 Seq. ID No. 68  51a Seq. ID No. 85 Seq. ID No. 86  51b Seq. ID No. 87 Seq. ID No. 88  66a Seq. ID No. 123 Seq. ID No. 124  73b Seq. ID No. 133 Seq. ID No. 134  80a Seq. ID No. 141 Seq. ID No. 142  86 Seq. ID No. 159 Seq. ID No. 160  87b Seq. ID No. 163 Seq. ID No. 164  99 Seq. ID No. 191 Seq. ID No. 192  109a Seq. ID No. 209 Seq. ID No. 210  109b Seq. ID No. 211 Seq. ID No. 212  109d Seq. ID No. 215 Seq. ID No. 216  111a Seq. ID No. 217 Seq. ID No. 218  114 Seq. ID No. 225 Seq. ID No. 226  124a Seq. ID No. 235 Seq. ID No. 236  124b Seq. ID No. 237 Seq. ID No. 238  129a Seq. ID No. 249 Seq. ID No. 250  129b Seq. ID No. 251 Seq. ID No. 252  132a Seq. ID No. 255 Seq. ID No. 256  138a Seq. ID No. 271 Seq. ID No. 272  143 Seq. ID No. 277 Seq. ID No. 278  145a Seq. ID No. 285 Seq. ID No. 286  145b Seq. ID No. 287 Seq. ID No. 288  145c Seq. ID No. 289 Seq. ID No. 290  162a Seq. ID No. 327 Seq. ID No. 328  162b Seq. ID No. 329 Seq. ID No. 330  180a Seq. ID No. 373 Seq. ID No. 374  180b Seq. ID No. 375 Seq. ID No. 376  201a Seq. ID No. 419 Seq. ID No. 420  239a Seq. ID No. 487 Seq. ID No. 488  245a Seq. ID No. 497 Seq. ID No. 498  245b Seq. ID No. 499 Seq. ID No. 500  246a Seq. ID No. 503 Seq. ID No. 504  246b Seq. ID No. 505 Seq. ID No. 506  248a Seq. ID No. 509 Seq. ID No. 510  248b Seq. ID No. 511 Seq. ID No. 512  249b Seq. ID No. 515 Seq. ID No. 516  255a Seq. ID No. 525 Seq. ID No. 526  255b Seq. ID No. 527 Seq. ID No. 528  263a Seq. ID No. 545 Seq. ID No. 546  273a Seq. ID No. 567 Seq. ID No. 568  273b Seq. ID No. 569 Seq. ID No. 570  277c Seq. ID No. 575 Seq. ID No. 576  279a Seq. ID No. 577 Seq. ID No. 578  279b Seq. ID No. 579 Seq. ID No. 580  283b Seq. ID No. 593 Seq. ID No. 594  297 Seq. ID No. 617 Seq. ID No. 618  311 Seq. ID No. 637 Seq. ID No. 638  313a Seq. ID No. 639 Seq. ID No. 640  313b Seq. ID No. 641 Seq. ID No. 642  313d Seq. ID No. 645 Seq. ID No. 646  317a Seq. ID No. 653 Seq. ID No. 654  317b Seq. ID No. 655 Seq. ID No. 656  318b Seq. ID No. 659 Seq. ID No. 660  321 Seq. ID No. 669 Seq. ID No. 670  324 Seq. ID No. 675 Seq. ID No. 676  327a Seq. ID No. 677 Seq. ID No. 678  327b Seq. ID No. 679 Seq. ID No. 680  342a Seq. ID No. 715 Seq. ID No. 716  342b Seq. ID No. 717 Seq. ID No. 718  342c Seq. ID No. 719 Seq. ID No. 720  342d Seq. ID No. 721 Seq. ID No. 722  342e Seq. ID No. 723 Seq. ID No. 724  349c Seq. ID No. 747 Seq. ID No. 748  350b Seq. ID No. 751 Seq. ID No. 752  352a Seq. ID No. 755 Seq. ID No. 756  352b Seq. ID No. 757 Seq. ID No. 758  352c Seq. ID No. 759 Seq. ID No. 760  354a Seq. ID No. 761 Seq. ID No. 762  354b Seq. ID No. 763 Seq. ID No. 764  356a Seq. ID No. 769 Seq. ID No. 770  358a Seq. ID No. 777 Seq. ID No. 778  358b Seq. ID No. 779 Seq. ID No. 780  372d Seq. ID No. 807 Seq. ID No. 808  374 Seq. ID No. 809 Seq. ID No. 810  382b Seq. ID No. 819 Seq. ID No. 820  384a Seq. ID No. 825 Seq. ID No. 826  403b Seq. ID No. 863 Seq. ID No. 864  418a Seq. ID No. 893 Seq. ID No. 894  419c Seq. ID No. 901 Seq. ID No. 902  431 Seq. ID No. 935 Seq. ID No. 936  437c Seq. ID No. 943 Seq. ID No. 944  441b Seq. ID No. 955 Seq. ID No. 956  448 Seq. ID No. 967 Seq. ID No. 968  452b Seq. ID No. 979 Seq. ID No. 980  462 Seq. ID No. 1005 Seq. ID No. 1006  463b Seq. ID No. 1009 Seq. ID No. 1010  464a Seq. ID No. 1011 Seq. ID No. 1012  464b Seq. ID No. 1013 Seq. ID No. 1014  464c Seq. ID No. 1015 Seq. ID No. 1016  465b Seq. ID No. 1019 Seq. ID No. 1020  472a Seq. ID No. 1029 Seq. ID No. 1030  472b Seq. ID No. 1031 Seq. ID No. 1032  472c Seq. ID No. 1033 Seq. ID No. 1034  472e Seq. ID No. 1037 Seq. ID No. 1038  472f Seq. ID No. 1039 Seq. ID No. 1040  476 Seq. ID No. 1045 Seq. ID No. 1046  480a Seq. ID No. 1055 Seq. ID No. 1056  492 Seq. ID No. 1075 Seq. ID No. 1076  507a Seq. ID No. 1105 Seq. ID No. 1106  521b Seq. ID No. 1131 Seq. ID No. 1132  524a Seq. ID No. 1135 Seq. ID No. 1136  524b Seq. ID No. 1137 Seq. ID No. 1138  541a Seq. ID No. 1165 Seq. ID No. 1166  541b Seq. ID No. 1167 Seq. ID No. 1168  541c Seq. ID No. 1169 Seq. ID No. 1170  545a Seq. ID No. 1183 Seq. ID No. 1184  546c Seq. ID No. 1193 Seq. ID No. 1194  547b Seq. ID No. 1197 Seq. ID No. 1198  556 Seq. ID No. 1213 Seq. ID No. 1214  561 Seq. ID No. 1223 Seq. ID No. 1224  564a Seq. ID No. 1227 Seq. ID No. 1228  564b Seq. ID No. 1229 Seq. ID No. 1230  570b Seq. ID No. 1237 Seq. ID No. 1238  576a Seq. ID No. 1243 Seq. ID No. 1244  587a Seq. ID No. 1265 Seq. ID No. 1266  587b Seq. ID No. 1267 Seq. ID No. 1268  587c Seq. ID No. 1269 Seq. ID No. 1270  587d Seq. ID No. 1271 Seq. ID No. 1272  595a Seq. ID No. 1283 Seq. ID No. 1284  596a Seq. ID No. 1287 Seq. ID No. 1288  596c Seq. ID No. 1291 Seq. ID No. 1292  598b Seq. ID No. 1297 Seq. ID No. 1298  600b Seq. ID No. 1305 Seq. ID No. 1306  609a Seq. ID No. 1315 Seq. ID No. 1316  613a Seq. ID No. 1325 Seq. ID No. 1326  613b Seq. ID No. 1327 Seq. ID No. 1328  613c Seq. ID No. 1329 Seq. ID No. 1330  613d Seq. ID No. 1331 Seq. ID No. 1332  619a Seq. ID No. 1341 Seq. ID No. 1342  624c Seq. ID No. 1353 Seq. ID No. 1354  631c Seq. ID No. 1367 Seq. ID No. 1368  645 Seq. ID No. 1401 Seq. ID No. 1402  665 Seq. ID No. 1429 Seq. ID No. 1430  674a Seq. ID No. 1435 Seq. ID No. 1436  679a Seq. ID No. 1445 Seq. ID No. 1446  700a Seq. ID No. 1481 Seq. ID No. 1482  722a Seq. ID No. 1513 Seq. ID No. 1514  722b Seq. ID No. 1515 Seq. ID No. 1516  722c Seq. ID No. 1517 Seq. ID No. 1518  728a Seq. ID No. 1529 Seq. ID No. 1530  730a Seq. ID No. 1533 Seq. ID No. 1534  730b Seq. ID No. 1535 Seq. ID No. 1536  738a Seq. ID No. 1545 Seq. ID No. 1546  738b Seq. ID No. 1547 Seq. ID No. 1548  739 Seq. ID No. 1551 Seq. ID No. 1552  743a Seq. ID No. 1559 Seq. ID No. 1560  744 Seq. ID No. 1563 Seq. ID No. 1564  746b Seq. ID No. 1571 Seq. ID No. 1572  749 Seq. ID No. 1579 Seq. ID No. 1580  754a Seq. ID No. 1583 Seq. ID No. 1584  754b Seq. ID No. 1585 Seq. ID No. 1586  772a Seq. ID No. 1621 Seq. ID No. 1622  779 Seq. ID No. 1633 Seq. ID No. 1634  786b Seq. ID No. 1643 Seq. ID No. 1644  788a Seq. ID No. 1645 Seq. ID No. 1646  788b Seq. ID No. 1647 Seq. ID No. 1648  789a Seq. ID No. 1649 Seq. ID No. 1650  789c Seq. ID No. 1653 Seq. ID No. 1654  799a Seq. ID No. 1671 Seq. ID No. 1672  799b Seq. ID No. 1673 Seq. ID No. 1674  799d Seq. ID No. 1677 Seq. ID No. 1678  799f Seq. ID No. 1681 Seq. ID No. 1682  826 Seq. ID No. 1707 Seq. ID No. 1708  837a Seq. ID No. 1731 Seq. ID No. 1732  837b Seq. ID No. 1733 Seq. ID No. 1734  843 Seq. ID No. 1737 Seq. ID No. 1738  853a Seq. ID No. 1753 Seq. ID No. 1754  853c Seq. ID No. 1757 Seq. ID No. 1758  859a Seq. ID No. 1765 Seq. ID No. 1766  859b Seq. ID No. 1767 Seq. ID No. 1768  868a Seq. ID No. 1787 Seq. ID No. 1788  870 Seq. ID No. 1791 Seq. ID No. 1792  873c Seq. ID No. 1797 Seq. ID No. 1798  876 Seq. ID No. 1805 Seq. ID No. 1806  885 Seq. ID No. 1819 Seq. ID No. 1820  886 Seq. ID No. 1821 Seq. ID No. 1822  887 Seq. ID No. 1823 Seq. ID No. 1824  908a Seq. ID No. 1839 Seq. ID No. 1840  929a Seq. ID No. 1869 Seq. ID No. 1870  931 Seq. ID No. 1875 Seq. ID No. 1876  939a Seq. ID No. 1891 Seq. ID No. 1892  939b Seq. ID No. 1893 Seq. ID No. 1894  939c Seq. ID No. 1895 Seq. ID No. 1896  952b Seq. ID No. 1923 Seq. ID No. 1924  955a Seq. ID No. 1927 Seq. ID No. 1928  977a Seq. ID No. 1969 Seq. ID No. 1970  981a Seq. ID No. 1981 Seq. ID No. 1982  987 Seq. ID No. 1991 Seq. ID No. 1992  988a Seq. ID No. 1993 Seq. ID No. 1994  998a Seq. ID No. 2013 Seq. ID No. 2014  999a Seq. ID No. 2017 Seq. ID No. 2018 1003b Seq. ID No. 2027 Seq. ID No. 2028 1006a Seq. ID No. 2033 Seq. ID No. 2034 1013a Seq. ID No. 2041 Seq. ID No. 2042 1017a Seq. ID No. 2049 Seq. ID No. 2050 1017c Seq. ID No. 2053 Seq. ID No. 2054 1036a Seq. ID No. 2087 Seq. ID No. 2088 1036b Seq. ID No. 2089 Seq. ID No. 2090 1044a Seq. ID No. 2105 Seq. ID No. 2106 1047b Seq. ID No. 2115 Seq. ID No. 2116 1050a Seq. ID No. 2121 Seq. ID No. 2122 1050d Seq. ID No. 2127 Seq. ID No. 2128 1065b Seq. ID No. 2151 Seq. ID No. 2152 1067 Seq. ID No. 2159 Seq. ID No. 2160 1077a Seq. ID No. 2171 Seq. ID No. 2172 1077b Seq. ID No. 2173 Seq. ID No. 2174 1077d Seq. ID No. 2177 Seq. ID No. 2178 1081a Seq. ID No. 2187 Seq. ID No. 2188 1111a Seq. ID No. 2237 Seq. ID No. 2238 1111b Seq. ID No. 2239 Seq. ID No. 2240 1125 Seq. ID No. 2245 Seq. ID No. 2246 1126b Seq. ID No. 2249 Seq. ID No. 2250 1140a Seq. ID No. 2271 Seq. ID No. 2272 1144a Seq. ID No. 2283 Seq. ID No. 2284 1146a Seq. ID No. 2289 Seq. ID No. 2290 1146b Seq. ID No. 2291 Seq. ID No. 2292 1146c Seq. ID No. 2293 Seq. 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ID No. 2428 1197 Seq. ID No. 2429 Seq. ID No. 2430 1199a Seq. ID No. 2433 Seq. ID No. 2434 1207 Seq. ID No. 2449 Seq. ID No. 2450 1212 Seq. ID No. 2459 Seq. ID No. 2460 1224b Seq. ID No. 2489 Seq. ID No. 2490 1228a Seq. ID No. 2497 Seq. ID No. 2498 1229c Seq. ID No. 2503 Seq. ID No. 2504 1231 Seq. ID No. 2507 Seq. ID No. 2508 1234a Seq. ID No. 2515 Seq. ID No. 2516 1236a Seq. ID No. 2523 Seq. ID No. 2524 1237 Seq. ID No. 2525 Seq. ID No. 2526 1241a Seq. ID No. 2531 Seq. ID No. 2532 1241c Seq. ID No. 2535 Seq. ID No. 2536 1243 Seq. ID No. 2537 Seq. ID No. 2538 1245a Seq. ID No. 2541 Seq. ID No. 2542 1245b Seq. ID No. 2543 Seq. ID No. 2544 1245c Seq. ID No. 2545 Seq. ID No. 2546 1250a Seq. ID No. 2555 Seq. ID No. 2556 1250b Seq. ID No. 2557 Seq. ID No. 2558 1253a Seq. ID No. 2569 Seq. ID No. 2570 1253b Seq. ID No. 2571 Seq. ID No. 2572 1258a Seq. ID No. 2583 Seq. ID No. 2584 1260 Seq. ID No. 2591 Seq. ID No. 2592 1266a Seq. ID No. 2597 Seq. ID No. 2598 1266b Seq. ID No. 2599 Seq. ID No. 2600 1267a Seq. ID No. 2601 Seq. ID No. 2602 1268b Seq. ID No. 2607 Seq. ID No. 2608 1270 Seq. ID No. 2611 Seq. ID No. 2612 1275a Seq. ID No. 2621 Seq. ID No. 2622 1278b Seq. ID No. 2629 Seq. ID No. 2630 1288 Seq. ID No. 2651 Seq. ID No. 2652 1308a Seq. ID No. 2679 Seq. ID No. 2680 1315 Seq. ID No. 2693 Seq. ID No. 2694 1319a Seq. ID No. 2701 Seq. ID No. 2702 1319b Seq. ID No. 2703 Seq. ID No. 2704 1320a Seq. ID No. 2705 Seq. ID No. 2706 1320b Seq. ID No. 2707 Seq. ID No. 2708 1334b Seq. ID No. 2731 Seq. ID No. 2732 1335a Seq. ID No. 2733 Seq. ID No. 2734 1365b Seq. ID No. 2783 Seq. ID No. 2784 1366a Seq. ID No. 2785 Seq. ID No. 2786 1381b Seq. ID No. 2813 Seq. ID No. 2814 1382 Seq. ID No. 2815 Seq. ID No. 2816 1384c Seq. ID No. 2823 Seq. ID No. 2824 1393a Seq. ID No. 2835 Seq. ID No. 2836 1393b Seq. ID No. 2837 Seq. ID No. 2838 1393d Seq. ID No. 2841 Seq. ID No. 2842 1399a Seq. ID No. 2853 Seq. ID No. 2854 1411a Seq. ID No. 2873 Seq. ID No. 2874 1411b Seq. ID No. 2875 Seq. 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ID No. 3044 1479c Seq. ID No. 3055 Seq. ID No. 3056 1484a Seq. ID No. 3063 Seq. ID No. 3064 1487 Seq. ID No. 3071 Seq. ID No. 3072 1488a Seq. ID No. 3073 Seq. ID No. 3074 1488b Seq. ID No. 3075 Seq. ID No. 3076 1488c Seq. ID No. 3077 Seq. ID No. 3078 1507c Seq. ID No. 3123 Seq. ID No. 3124 1517a Seq. ID No. 3145 Seq. ID No. 3146 1520 Seq. ID No. 3155 Seq. ID No. 3156 1522 Seq. ID No. 3157 Seq. ID No. 3158 1530a Seq. ID No. 3163 Seq. ID No. 3164 1543 Seq. ID No. 3183 Seq. ID No. 3184 1552 Seq. ID No. 3193 Seq. ID No. 3194 1554b Seq. ID No. 3201 Seq. ID No. 3202 1557a Seq. ID No. 3213 Seq. ID No. 3214 1557b Seq. ID No. 3215 Seq. ID No. 3216 1557c Seq. ID No. 3217 Seq. ID No. 3218 1559a Seq. ID No. 3219 Seq. ID No. 3220 1572a Seq. ID No. 3241 Seq. ID No. 3242 1572b Seq. ID No. 3243 Seq. ID No. 3244 1572c Seq. ID No. 3245 Seq. ID No. 3246 1572e Seq. ID No. 3249 Seq. ID No. 3250 1577b Seq. ID No. 3257 Seq. ID No. 3258 1580a Seq. ID No. 3261 Seq. ID No. 3262 1582b Seq. ID No. 3269 Seq. ID No. 3270 1585a Seq. ID No. 3275 Seq. ID No. 3276 1594a Seq. ID No. 3297 Seq. ID No. 3298 1606a Seq. ID No. 3317 Seq. ID No. 3318 1607b Seq. ID No. 3323 Seq. ID No. 3324 1619 Seq. ID No. 3337 Seq. ID No. 3338 1621 Seq. ID No. 3339 Seq. ID No. 3340 1624 Seq. ID No. 3349 Seq. ID No. 3350 1625a Seq. ID No. 3351 Seq. ID No. 3352 1625b Seq. ID No. 3353 Seq. ID No. 3354 1626a Seq. ID No. 3357 Seq. ID No. 3358 1626b Seq. ID No. 3359 Seq. ID No. 3360 1634c Seq. ID No. 3377 Seq. ID No. 3378 1646a Seq. ID No. 3389 Seq. ID No. 3390 1646b Seq. ID No. 3391 Seq. ID No. 3392 1646d Seq. ID No. 3395 Seq. ID No. 3396 1649a Seq. ID No. 3405 Seq. ID No. 3406 1659a Seq. ID No. 3421 Seq. ID No. 3422 1659c Seq. ID No. 3425 Seq. ID No. 3426 1673a Seq. ID No. 3449 Seq. ID No. 3450 1673b Seq. ID No. 3451 Seq. ID No. 3452 1673c Seq. ID No. 3453 Seq. ID No. 3454 1673d Seq. ID No. 3455 Seq. ID No. 3456 1673e Seq. ID No. 3457 Seq. ID No. 3458 1675a Seq. ID No. 3463 Seq. ID No. 3464 1683a Seq. ID No. 3481 Seq. 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ID No. 4738 2276a Seq. ID No. 4759 Seq. ID No. 4760 2300 Seq. ID No. 4813 Seq. ID No. 4814 2308 Seq. ID No. 4827 Seq. ID No. 4828 2329a Seq. ID No. 4869 Seq. ID No. 4870 2329b Seq. ID No. 4871 Seq. ID No. 4872 2329c Seq. ID No. 4873 Seq. ID No. 4874 2329d Seq. ID No. 4875 Seq. ID No. 4876 2357 Seq. ID No. 4919 Seq. ID No. 4920 2363b Seq. ID No. 4931 Seq. ID No. 4932 2371a Seq. ID No. 4949 Seq. ID No. 4950 2372 Seq. ID No. 4951 Seq. ID No. 4952 2390 Seq. ID No. 4987 Seq. ID No. 4988 2412 Seq. ID No. 5031 Seq. ID No. 5032 2423a Seq. ID No. 5061 Seq. ID No. 5062 2434 Seq. ID No. 5085 Seq. ID No. 5086 2445 Seq. ID No. 5103 Seq. ID No. 5104 2456c Seq. ID No. 5123 Seq. ID No. 5124 2458a Seq. ID No. 5129 Seq. ID No. 5130 2458b Seq. ID No. 5131 Seq. ID No. 5132 2458d Seq. ID No. 5135 Seq. ID No. 5136 2458e Seq. ID No. 5137 Seq. ID No. 5138 2458g Seq. ID No. 5141 Seq. ID No. 5142 2469b Seq. ID No. 5165 Seq. ID No. 5166 2474b Seq. ID No. 5175 Seq. ID No. 5176 2484b Seq. ID No. 5199 Seq. ID No. 5200 2490 Seq. ID No. 5205 Seq. ID No. 5206 2492a Seq. ID No. 5207 Seq. ID No. 5208 2495a Seq. ID No. 5213 Seq. ID No. 5214 2497b Seq. ID No. 5219 Seq. ID No. 5220 2500a Seq. ID No. 5223 Seq. ID No. 5224 2518a Seq. ID No. 5267 Seq. ID No. 5268 2521 Seq. ID No. 5281 Seq. ID No. 5282 2567a Seq. ID No. 5385 Seq. ID No. 5386 2567b Seq. ID No. 5387 Seq. ID No. 5388 2587a Seq. ID No. 5413 Seq. ID No. 5414 2587b Seq. ID No. 5415 Seq. ID No. 5416 2596 Seq. ID No. 5433 Seq. ID No. 5434 2610 Seq. ID No. 5453 Seq. ID No. 5454 2616a Seq. ID No. 5459 Seq. ID No. 5460 2616b Seq. ID No. 5461 Seq. ID No. 5462 2616c Seq. ID No. 5463 Seq. ID No. 5464 2616d Seq. ID No. 5465 Seq. ID No. 5466 2623b Seq. ID No. 5491 Seq. ID No. 5492 2625a Seq. ID No. 5497 Seq. ID No. 5498 2628 Seq. ID No. 5509 Seq. ID No. 5510 2629b Seq. ID No. 5513 Seq. ID No. 5514 2633d Seq. ID No. 5525 Seq. ID No. 5526 2637b Seq. ID No. 5531 Seq. ID No. 5532 2660 Seq. ID No. 5569 Seq. ID No. 5570 2669a Seq. ID No. 5587 Seq. ID No. 5588 2673 Seq. ID No. 5595 Seq. ID No. 5596 2674a Seq. ID No. 5597 Seq. ID No. 5598 2679a Seq. ID No. 5609 Seq. ID No. 5610 2679b Seq. ID No. 5611 Seq. ID No. 5612 2680c Seq. ID No. 5621 Seq. ID No. 5622 2683a Seq. ID No. 5623 Seq. ID No. 5624 2688a Seq. ID No. 5633 Seq. ID No. 5634 2688c Seq. ID No. 5637 Seq. ID No. 5638 2690a Seq. ID No. 5643 Seq. ID No. 5644 2692b Seq. ID No. 5649 Seq. ID No. 5650 2696a Seq. ID No. 5659 Seq. ID No. 5660 2718b Seq. ID No. 5683 Seq. ID No. 5684 2718c Seq. ID No. 5685 Seq. ID No. 5686 2723 Seq. ID No. 5699 Seq. ID No. 5700 2725b Seq. ID No. 5705 Seq. ID No. 5706 2728a Seq. ID No. 5709 Seq. ID No. 5710 2738a Seq. ID No. 5729 Seq. ID No. 5730 2738c Seq. ID No. 5733 Seq. ID No. 5734 2749a Seq. ID No. 5763 Seq. ID No. 5764 2749b Seq. ID No. 5765 Seq. ID No. 5766 2749c Seq. ID No. 5767 Seq. ID No. 5768 2749e Seq. ID No. 5771 Seq. ID No. 5772 2757b Seq. ID No. 5783 Seq. ID No. 5784 2758d Seq. ID No. 5791 Seq. ID No. 5792 2760a Seq. ID No. 5797 Seq. ID No. 5798 2796a Seq. ID No. 5885 Seq. ID No. 5886 2799a Seq. ID No. 5889 Seq. ID No. 5890 2801a Seq. ID No. 5893 Seq. ID No. 5894 2801b Seq. ID No. 5895 Seq. ID No. 5896 2805a Seq. ID No. 5899 Seq. ID No. 5900 2805b Seq. ID No. 5901 Seq. ID No. 5902 2810a Seq. ID No. 5905 Seq. ID No. 5906 2810c Seq. ID No. 5909 Seq. ID No. 5910 2818a Seq. ID No. 5921 Seq. ID No. 5922 2818b Seq. ID No. 5923 Seq. ID No. 5924 2818d Seq. ID No. 5927 Seq. ID No. 5928 2822a Seq. ID No. 5939 Seq. ID No. 5940 2869c Seq. ID No. 6027 Seq. ID No. 6028 2881 Seq. ID No. 6043 Seq. ID No. 6044 2883a Seq. ID No. 6047 Seq. ID No. 6048 2887a Seq. ID No. 6059 Seq. ID No. 6060 2891a Seq. ID No. 6067 Seq. ID No. 6068 2900b Seq. ID No. 6089 Seq. ID No. 6090 2901a Seq. ID No. 6091 Seq. ID No. 6092 2909b Seq. ID No. 6107 Seq. ID No. 6108 2909d Seq. ID No. 6111 Seq. ID No. 6112 2913b Seq. ID No. 6117 Seq. ID No. 6118 2931a Seq. ID No. 6161 Seq. ID No. 6162 2931b Seq. ID No. 6163 Seq. ID No. 6164 2931c Seq. ID No. 6165 Seq. ID No. 6166 2933b Seq. ID No. 6169 Seq. ID No. 6170 2941a Seq. ID No. 6183 Seq. ID No. 6184 2941b Seq. ID No. 6185 Seq. ID No. 6186 2943a Seq. ID No. 6189 Seq. ID No. 6190 2943b Seq. ID No. 6191 Seq. ID No. 6192 2944b Seq. ID No. 6197 Seq. ID No. 6198 2948a Seq. ID No. 6203 Seq. ID No. 6204 2948b Seq. ID No. 6205 Seq. ID No. 6206 2948d Seq. ID No. 6209 Seq. ID No. 6210 2955a Seq. ID No. 6221 Seq. ID No. 6222 2955b Seq. ID No. 6223 Seq. ID No. 6224 2955c Seq. ID No. 6225 Seq. ID No. 6226 2955d Seq. ID No. 6227 Seq. ID No. 6228 2955e Seq. ID No. 6229 Seq. ID No. 6230 2957 Seq. ID No. 6235 Seq. ID No. 6236 2958a Seq. ID No. 6237 Seq. ID No. 6238 2959 Seq. ID No. 6243 Seq. ID No. 6244 2960a Seq. ID No. 6245 Seq. ID No. 6246 2962b Seq. ID No. 6249 Seq. ID No. 6250 2965a Seq. ID No. 6253 Seq. ID No. 6254 2969 Seq. ID No. 6263 Seq. ID No. 6264 2970a Seq. ID No. 6265 Seq. ID No. 6266 2974a Seq. ID No. 6273 Seq. ID No. 6274 2974b Seq. ID No. 6275 Seq. ID No. 6276 2978b Seq. ID No. 6285 Seq. ID No. 6286 2980a Seq. ID No. 6289 Seq. ID No. 6290 2986a Seq. ID No. 6301 Seq. ID No. 6302 2986b Seq. ID No. 6303 Seq. ID No. 6304 3016a Seq. ID No. 6363 Seq. ID No. 6364 3021 Seq. ID No. 6377 Seq. ID No. 6378 3023 Seq. ID No. 6381 Seq. ID No. 6382 3024a Seq. ID No. 6383 Seq. ID No. 6384 3037a Seq. ID No. 6415 Seq. ID No. 6416 3042b Seq. ID No. 6427 Seq. ID No. 6428 3043b Seq. ID No. 6431 Seq. ID No. 6432 3064b Seq. ID No. 6473 Seq. ID No. 6474 3076 Seq. ID No. 6497 Seq. ID No. 6498 3107a Seq. ID No. 6571 Seq. ID No. 6572 3110a Seq. ID No. 6581 Seq. ID No. 6582 3119a Seq. ID No. 6593 Seq. ID No. 6594 3119d Seq. ID No. 6599 Seq. ID No. 6600 3140 Seq. ID No. 6631 Seq. ID No. 6632 3145c Seq. ID No. 6639 Seq. ID No. 6640

B. ALLOIOCOCCUS OTITIDIS ORF POLYNUCLEOTIDES ENCODING SURFACE EXPOSED POLYPEPTIDES

Isolated and purified Alloiococcus otitidis ORF polynucleotides of the present invention are contemplated for use in the production of Alloiococcus otitidis polypeptides. More specifically, in certain embodiments, the ORFs encode Alloiococcus otitidis surface exposed polypeptides, particularly antigenic polypeptides. Thus, in one aspect, the present invention provides isolated and purified polynucleotides (ORFS) that encode Alloiococcus otitidis surface exposed polypeptides. In particular embodiments, a polynucleotide of the present invention is a DNA molecule, wherein the DNA may be genomic DNA, plasmid DNA or cDNA. In a preferred embodiment, a polynucleotide of the present invention is a recombinant polynucleotide, which encodes an Alloiococcus otitidis polypeptide comprising an amino acid sequence that has at least 70% identity to an amino acid sequence of one of the even numbered sequences set forth in SEQ ID NO: 2 through SEQ ID NO: 6650 or a fragment thereof. In another embodiment, an isolated and purified ORF polynucleotide comprises a nucleotide sequence that has at least 70% identity to one of the ORF polynucleotide nucleotide sequences of odd numbered sequences set forth in SEQ ID NO: 1 through SEQ ID NO: 6649, a degenerate variant thereof, or a complement thereof. In yet another embodiment, an ORF polynucleotide of one of the odd numbered sequences set forth in SEQ ID NO: 1 through SEQ ID NO: 6649 is comprised in a plasmid vector and expressed in a host cell. In a preferred embodiment, the host cell is a prokaryotic host cell.

As used herein, the term “polynucleotide” means a sequence of nucleotides connected by phosphodiester linkages. It is well understood that in all prokaryotes studied to date, including Alloiococcus otitidis , most or all cellular genetic material is contained within a single circular chromosome. The single circular chromosome is usually comprised of double stranded DNA, wherein the ORFs encoding polypeptides may be represented on either strand of the bacterial chromosome in a head to tail or a head to head orientation. Polynucleotides are presented herein from the 5′ to the 3′ direction. A polynucleotide of the present invention can comprise from about 10 nucleotides to about several hundred thousand nucleotides. Preferably, a polynucleotide comprises from about 10 to about 3,000 nucleotides. Preferred lengths of particular polynucleotide are set forth hereinafter.

A polynucleotide of the present invention can be a deoxyribonucleic acid (DNA) molecule, a ribonucleic acid (RNA) molecule, or analogs of the DNA or RNA generated using nucleotide analogs. The nucleic acid molecule can be single-stranded or double-stranded, but preferably is double-stranded DNA. Where a polynucleotide is a DNA molecule, that molecule can be a gene, a cDNA molecule or a genomic DNA molecule. Nucleotide bases are indicated herein by a single letter code: adenine (A), guanine (G), thymine (T) and cytosine (C).

“Isolated” means altered “by the hand of man” from the natural state. An “isolated” composition or substance is one that has been changed or removed from its original environment, or both. For example, a polynucleotide or a polypeptide naturally present in a living animal is not “isolated,” but the same polynucleotide or polypeptide separated from the coexisting materials of its natural state is “isolated,” as the term is employed herein.

Preferably, an “isolated” polynucleotide is free of sequences, which naturally flank the nucleic acid (ie., sequences located at the 5′ and 3′ ends of the nucleic acid) in the genomic DNA of the organism from which the nucleic acid is derived. For example, in various embodiments, the isolated Alloiococcus otitidis nucleic acid molecule can contain less than about 5 kb, 4 kb, 3 kb, 2 kb, 1 kb, 0.5 kb or 0.1 kb of nucleotide sequences which naturally flank the nucleic acid molecule in genomic DNA of the cell from which the nucleic acid is derived (e.g., neuronal or placenta). However, the Alloiococcus otitidis nucleic acid molecule can be fused to heterologous protein encoding or regulatory sequences and still be considered isolated.

ORF polynucleotides of the present invention are obtained using standard cloning and screening techniques from a cDNA library derived from mRNA. Polynucleotides of the invention are also obtained from natural sources such as genomic DNA libraries (e.g., an Alloiococcus otitidis library) or are synthesized using well known and commercially available techniques. As contemplated in the present invention, ORF polynucleotides are obtained using Alloiococcus otitidis chromosomal DNA as the template.

The invention further encompasses nucleic acid molecules that differ from the nucleotide sequences shown in one of the odd numbered sequences set forth in SEQ ID NO: 1 through SEQ ID NO: 6649 (and fragments thereof) due to degeneracy of the genetic code, and thus encode the same Alloiococcus otitidis polypeptide as that encoded by the nucleotide sequence shown in one of the odd numbered sequences set forth in SEQ ID NO:1 through SEQ ID NO: 6649.

Orthologs and allelic variants of the Alloiococcus otitidis polynucleotides are readily identified using methods well known in the art. Allelic variants and orthologs of the polynucleotides comprise a nucleotide sequence that is typically at least about 70-75%, more typically at least about 80-85%, and most typically at least about 90-95% or more homologous to a nucleotide sequence shown in one of the odd numbered sequences set forth in SEQ ID NO:1 through SEQ ID NO: 6649, or a fragment of these nucleotide sequences. Such nucleic acid molecules are readily identified as being able to hybridize, preferably under stringent conditions, to a nucleotide sequence shown in one of the odd numbered sequences set forth in SEQ ID NO:1 through SEQ ID NO: 6649, or a fragment of these nucleotide sequences.

Moreover, the polynucleotides of the invention also comprise only a fragment of the coding region of an Alloiococcus otitidis polynucleotide or gene, such as a fragment of and one of the odd numbered sequences set forth in SEQ ID NO:1 through SEQ ID NO: 6649. Preferably, such fragments encode polypeptides, which are immunogenic fragments.

When the ORF polynucleotides of the invention are used for the recombinant production of Alloiococcus otitidis polypeptides of the present invention, the polynucleotide may include the coding sequence for the mature polypeptide, by itself, or the coding sequence for the mature polypeptide in reading frame with other coding sequences, such as those encoding a leader or secretory sequence, a pre-, or pro- or prepro-protein sequence, or other fusion peptide portions. For example, a marker sequence, which facilitates purification of the fused polypeptide, can be linked to the coding sequence (see Gentz et al., 1989, incorporated herein by reference). Thus, contemplated in the present invention is the preparation of polynucleotides encoding fusion polypeptides permitting His-tag purification of expression products. The polynucleotide may also contain non-coding 5′ and 3′ sequences, such as transcribed, non-translated sequences, splicing and polyadenylation signals.

Thus, a polynucleotide encoding a polypeptide of the present invention, including homologs and orthologs from species other than Alloiococcus otitidis , is obtained by a process which comprises the steps of screening an appropriate library under stringent hybridization conditions (discussed below) with a labeled probe having the sequence of one of the odd numbered sequences set forth in one of SEQ ID NO:1 through SEQ ID NO: 6649 or a fragment thereof; and isolating full-length cDNA and genomic clones containing the polynucleotide sequence. Such hybridization techniques are well known to the skilled artisan. The skilled artisan will appreciate that, in many cases, an isolated cDNA sequence will be incomplete, in that the region coding for the polypeptide is cut short at the 5′ end of the cDNA. This is a consequence of reverse transcriptase, an enzyme with inherently low “processivity” (a measure of the ability of the enzyme to remain attached to the template during the polymerization reaction), failing to complete a DNA copy of the mRNA template during 1st strand cDNA synthesis.

Thus, in certain embodiments, the polynucleotide sequence information provided by the present invention allows for the preparation of relatively short DNA (or RNA) oligonucleotide sequences having the ability to specifically hybridize to gene sequences of the selected polynucleotides disclosed herein. The term “oligonucleotide” as used herein is defined as a molecule comprised of two or more deoxyribonucleotides or ribonucleotides, usually more than three (3), and typically more than ten (10) and up to one hundred (100) or more (although preferably between twenty and thirty). The exact size will depend on many factors, which in turn depends on the ultimate function or use of the oligonucleotide. Thus, in particular embodiments of the invention, nucleic acid probes of an appropriate length are prepared based on a consideration of a selected nucleotide sequence, e.g., a sequence such as that shown in one of odd numbered sequences set forth in SEQ ID NO:1 through SEQ ID NO: 6649. The ability of such nucleic acid probes to specifically hybridize to a polynucleotide encoding an Alloiococcus otitidis polypeptide lends them particular utility in a variety of embodiments. Most importantly, the probes are used in a variety of assays for detecting the presence of complementary sequences in a given sample.

In certain embodiments, it is advantageous to use oligonucleotide primers. These primers may be generated in any manner, including chemical synthesis, DNA replication, reverse transcription, or a combination thereof. The sequence of such primers is designed using a polynucleotide of the present invention for use in detecting, amplifying or mutating a defined segment of an ORF polynucleotide that encodes an Alloiococcus otitidis polypeptide from prokaryotic cells using polymerase chain reaction (PCR) technology.

In certain embodiments, it is advantageous to employ a polynucleotide of the present invention in combination with an appropriate label for detecting hybrid formation. A wide variety of appropriate labels are known in the art, including radioactive, enzymatic or other ligands, such as avidin/biotin, which are capable of giving a detectable signal.

Polynucleotides which are identical or sufficiently identical to a nucleotide sequence contained in one of odd numbered sequences set forth in SEQ ID NO:1 through SEQ ID NO: 6649, or a fragment thereof, may be used as hybridization probes for cDNA and genomic DNA or as primers for a nucleic acid amplification (PCR) reaction, to isolate full-length cDNAs and genomic clones encoding polypeptides of the present invention and to isolate cDNA and genomic clones of other genes (including genes encoding homologs and orthologs from species other than Alloiococcus otitidis ) that have a high sequence similarity to polynucleotide sequences set forth in one of the odd numbered sequences set forth in SEQ ID NO:1 through SEQ ID NO:6649, or a fragment thereof. Typically these nucleotide sequences are from at least 70% identical to at least about 70% identical to that of the reference polynucleotide sequence. The probes or primers will generally comprise at least 15 nucleotides, preferably, at least 30 nucleotides and may have at least 50 nucleotides. Particularly preferred probes will have between 30 and 50 nucleotides.

There are several methods available and well known to those skilled in the art to obtain full-length cDNAs, or extend short cDNAs, for example those based on the method of Rapid Amplification of cDNA ends (RACE) (see, Frohman et al., 1988). Recent modifications of the technique, exemplified by the Marathon™ technology (BD Biosciences Clontech, Palo Alto, Calif.) for example, have significantly simplified the search for longer cDNAs. In the Marathon™ technology, cDNAs have been prepared from mRNA extracted from a chosen tissue and an “adaptor” sequence ligated onto each end. Nucleic acid amplification (PCR) is then carried out to amplify the “rhissing” 5′ end of the cDNA using a combination of gene specific and adaptor specific oligonucleotide primers. The PCR reaction is then repeated using “nested” primers, that is, primers designed to anneal within the amplified product (typically an adaptor specific primer that anneals further 3′ in the adaptor sequence and a gene specific primer that anneals further 5′ in the known gene sequence). The products of this reaction are then analyzed by DNA sequencing and a full-length cDNA constructed either by joining the product directly to the existing cDNA to give a complete sequence, or carrying out a separate full-length PCR using the new sequence information for the design of the 5′ primer.

To provide certain of the advantages in accordance with the present invention, a preferred nucleic acid sequence employed for hybridization studies or assays includes probe molecules that are complementary to at least a 10 to about 70 long nucleotide stretch of a polynucleotide that encodes an Alloiococcus otitidis polypeptide, such as that shown in one of the even numbered sequences set forth in SEQ ID NO: 2 through SEQ ID NO: 6650. A size of at least 10 nucleotides in length helps to ensure that the fragment will be of sufficient length to form a duplex molecule that is both stable and selective. Molecules having complementary sequences over stretches greater than 10 bases in length are generally preferred in order to increase stability and selectivity of the hybrid, and thereby improve the quality and degree of specific hybrid molecules obtained. It is generally preferred to design nucleic acid molecules with gene-complementary stretches of 25 to 40 nucleotides, 55 to 70 nucleotides, or even longer where desired. For example, such fragments are readily prepared by directly synthesizing the fragment by chemical means, by application of nucleic acid reproduction technology, such as the PCR technology (U.S. Pat. No. 4,683,202, incorporated herein by reference), or by excising selected DNA fragments from recombinant plasmids containing appropriate inserts and suitable restriction enzyme sites.

In another aspect, the present invention contemplates an isolated and purified polynucleotide comprising a nucleotide sequence that is identical or complementary to a segment of at least 10 contiguous bases of one of the odd numbered sequences set forth in SEQ ID NO: 1 through SEQ ID NO: 6649, wherein the polynucleotide hybridizes to a polynucleotide that encodes an Alloiococcus otitidis polypeptide. Preferably, the isolated and purified polynucleotide comprises a base sequence that is identical or complementary to a segment of at least 25 to 70 contiguous bases of one of the odd numbered sequences set forth in SEQ ID NO: 1 through SEQ ID NO: 6649. For example, the polynucleotide of the invention can comprise a segment of bases identical or complementary to from 40 to 55 contiguous bases of the disclosed nucleotide sequences.

Accordingly, a polynucleotide probe molecule of the invention is used for its ability to selectively form duplex molecules with complementary stretches of the gene. Depending on the application envisioned, one will desire to employ varying conditions of hybridization stringency to achieve varying degree of selectivity of the probe toward the target sequence (see Table 22 below). For applications requiring a high degree of selectivity, one will typically desire to employ relatively stringent conditions to form the hybrids. For some applications, for example, where one desires to prepare mutants employing a mutant primer strand hybridized to an underlying template or where one seeks to isolate an Alloiococcus otitidis homologous polypeptide coding sequence from other cells, functional equivalents, or the like, less stringent hybridization conditions are typically needed to allow formation of the heteroduplex (see Table 22). Cross-hydridizing species can thereby be readily identified as positively hybridizing signals with respect to control hybridizations. In any case, it is generally appreciated that conditions can be rendered more stringent by the addition of increasing amounts of formamide, which serves to destabilize the hybrid duplex in the same manner as increased temperature. Thus, hybridization conditions can be readily manipulated, and thus will generally be a method of choice depending on the desired results.

The present invention also includes polynucleotides capable of hybridizing under reduced stringency conditions, more preferably stringent conditions, and most preferably highly, stringent conditions, to polynucleotides described herein. Examples of stringency conditions are shown in the Table 22 below: highly stringent conditions are those that are at least as stringent as, for example, conditions A-F; stringent conditions are at least as stringent as, for example, conditions G-L; and reduced stringency conditions are at least as stringent as, for example, conditions M-R. TABLE 22 HYBRIDIZATION STRINGENCY CONDITIONS Hybridization Stringency Polynucleotide Hybrid Temperature Wash Temperature Condition Hybrid Length (bp)¹ and Buffer^(H) and Buffer^(H) A DNA:DNA >50 65° C.; 1 × SSC -or- 65° C.; 0.3 × SSC 42° C.; 1 × SSC, 50% formamide B DNA:DNA <50 T_(B); 1 × SSC T_(B); 1 × SSC C DNA:RNA >50 67° C.; 1 × SSC - 67° C.; 0.3 × SSC or- 45° C.; 1 × SSC, 50% formamide D DNA:RNA <50 T_(D); 1 × SSC T_(D); 1 × SSC E RNA:RNA >50 70° C.; 1 × SSC - 70° C.; 0.3 × SSC or- 50° C.; 1 × SSC, 50% formamide F RNA:RNA <50 T_(F); 1 × SSC T_(F); 1 × SSC G DNA:DNA >50 65° C.; 4 × SSC - 65 0; 1 × SSC or- 42° C.; 4 × SSC, 50% formamide H DNA:DNA <50 T_(H); 4 × SSC T_(H); 4 × SSC I DNA:RNA >50 67° C.; 4 × SSC - 67° C.; 1 × SSC or- 45° C.; 4 × SSC, 50% formamide J DNA:RNA <50 T_(J); 4 × SSC T_(J); 4 × SSC K RNA:RNA >50 70° C.; 4 × SSC - 67° C.; 1 × SSC or- 50° C.; 4 × SSC, 50% formamide L RNA:RNA <50 T_(L); 2 × SSC T_(L); 2 × SSC M DNA:DNA >50 50° C.; 4 × SSC - 50° C.; 2 × SSC or- 40° C.; 6 × SSC, 50% formamide N DNA:DNA <50 T_(N); 6 × SSC T_(N); 6 × SSC O DNA:RNA >50 55° C.; 4 × SSC - 55° C.; 2 × SSC or- 42° C.; 6 × SSC, 50% formamide P DNA:RNA <50 T_(P); 6 × SSC T_(P); 6 × SSC Q RNA:RNA >50 60° C.; 4 × SSC - 60° C.; 2 × SSC or- 45° C.; 6 × SSC, 50% formamide R RNA:RNA <50 T_(R); 4 × SSC T_(R); 4 × SSC (bp)¹: The hybrid length is that anticipated for the hybridized region(s) of the hybridizing polynucleotides. When hybridizing a polynucleotide to a target polynucleotide of unknown sequence, the hybrid length is assumed to be that of the hybridizing polynucleotide. When polynucleotides of known sequence are hybridized, the hybrid # length is determined by aligning the sequences of the polynucleotides and identifying the region or regions of optimal sequence complementarity. Buffer^(H): SSPE (1 × SSPE is 0.15 M NaCl, 10 mM NaH₂PO₄, and 1.25 mM EDTA, pH 7.4), can be substituted for SSC (1 × SSC is 0.15 M NaCl and 15 mM sodium citrate) in the hybridization and wash buffers; washes are performed for 15 minutes after hybridization is complete. T_(B) through T_(R): The hybridization temperature for hybrids anticipated to be less than 50 base pairs in length should be 5-10° C. less than the melting temperature (T_(m)) of the hybrid, where T_(m) is determined according to the following equations. For hybrids less than 18 base pairs in length, T_(m)(° C.) = 2(# of A + T bases) + 4(# of G + C bases). # For hybrids between 18 and 49 base pairs in length, T_(m)(° C.) = 81.5 + 16.6(log₁₀[Na⁺]) + 0.41 (% G + C) − (600/N), where N is the number of bases in the hybrid, and [Na⁺] is the concentration of sodium ions in the hybridization buffer ([Na⁺] for 1 × SSC = 0.165 M).

Additional examples of stringency conditions for polynucleotide hybridization are provided in Sambrook et al., 1.989, Molecular Cloning: A Laboratory Manual, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y., chapters 9 and 11, and Ausubel et al., 1995, Current Protocols in Molecular Biology, Eds., John Wiley & Sons, Inc., sections 2.10 and 6.3-6.4, incorporated herein by reference.

In addition to the nucleic acid molecules encoding Alloiococcus otitidis polypeptides described above, another aspect of the invention pertains to isolated nucleic acid molecules that are antisense thereto. An “antisense” nucleic acid comprises a nucleotide sequence that is complementary to a “sense” nucleic acid encoding a protein, e.g., complementary to the coding strand of a double-stranded cDNA molecule or complementary to an mRNA sequence. Accordingly, an antisense nucleic acid can hydrogen bond to a sense nucleic acid. The antisense nucleic acid can be complementary to an entire Alloiococcus otitidis coding strand, or to only a fragment thereof. In one embodiment, an antisense nucleic acid molecule is antisense to a “coding region” of the coding strand of a nucleotide sequence encoding an Alloiococcus otitidis polypeptide.

The term “coding region” refers to the region of the nucleotide sequence comprising codons which are translated into amino acid residues, e.g., the entire coding region of each of odd numbered sequences set forth in SEQ ID NO: 1 through SEQ ID NO: 6649. In another embodiment, the antsense nucleic acid molecule is antisense to a “noncoding region” of the coding strand of a nucleofide sequence encoding an Alloiococcus otitidis polypeptide. The term “noncoding region” refers to 5′ and 3′ sequences that flank the coding region that are not translated into amino acids (i.e., also referred to as 5′ and 3′ untranslated regions).

Given the coding strand sequence encoding the Alloiococcus otitidis polypeptides disclosed herein antisense nucleic acids of the invention can be designed according to the rules of Watson and Crick base pairing. The antisense nucleic acid molecule can be complementary to the entire coding region of Alloiococcus otitidis mRNA, but more preferably is an oligonucleotide which is antisense to only a fragment of the coding or noncoding region of Alloiococcus otitidis mRNA. For example, the antisense oligonucleotide can be complementary to the region surrounding the translation start site of Alloiococcus otitidis mRNA.

An antisense oligonucleotide can be, for example, about 5, 10, 15,20, 25, 30, 35, 40, 45 or 50 nucleotides in length. An antisense nucleic acid of the invention can be constructed using chemical synthesis and enzymatic ligation reactions using procedures known in the art. For example, an antisense nucleic acid (e.g., an antisense oligonucleotide) can be chemically synthesized using naturally occurring nucleotides or variously modified nucleotides designed to increase the biological stability of the molecules or to increase the physical stability of the duplex formed between the antisense and sense nucleic acids, e.g., phosphorothioate derivatives and acridine substituted nucleotides can be used. Examples of modified nucleotides which can be used to generate the antisense nucleic acid include 5-fluorouracil, 5-bromouracil, 5-chlorouracil, 5-iodouracil, hypoxanthine, xanthine, 4-acetylcytosine, 5-(carboxyhydroxylmethyl)uracil, 5-carboxymethylaminomethyl-2-thiouridine, 5-carboxymethylaminomethyluracil, dihydrouracil, beta-D-galactosylqueosine, inosine, N6-isopentenyladenine, 1-methylguanine, 1-methylinosine, 2,2-dimethylguanine, 2-methyladenine, 2-methylguanine, 3-methylcytosine, 5-methylcytosine, N6-adenine, 7-methylguanine, 5-methylaminomethyluracil, 5-methoxyaminomethyl-2-thiouracil, beta-D-mannosylqueosine, 5′-methoxycarboxymethyluracil, 5-methoxyuracil, 2-methylthio-N6-isopentenyladenine, uracil-5-oxyacetic acid (v), wybutoxosine, pseudouracil, queosine, 2-thiocytosine, 5-methyl-2-thiouracil, 2-thiouracil, 4-thiouracil, 5-methyluracil, uracil-5-oxyacetic acid methylester, uracil-5-oxyacetic acid (v), 5-methyl-2-thiouracil, 3-(3-amino-3-N-2-carboxypropyl) uracil, (acp3)w, and 2,6-diaminopurine.

Alternatively, the antisense nucleic acid can be produced biologically using an expression vector into which a nucleic acid has been subcloned in an antisense orientation (i.e., RNA transcribed from the inserted nucleic acid will be of an antisense orientation to a target nucleic acid of interest, described further in the following subsection).

The antisense nucleic acid molecules of the invention are typically administered to a subject or generated in situ such that they hybridize with or bind to cellular mRNA and/or genomic DNA encoding an Alloiococcus otitidis polypeptide to thereby inhibit expression of the polypeptide, e.g., by inhibiting transcription and/or translation. The hybridization can be by conventional nucleotide complementarity to form a stable duplex, or, for example, in the case of an antisense nucleic acid molecule which binds to DNA duplexes, through specific interactions in the major groove of the double helix. An example of a route of administration of an antisense nucleic acid molecule of the invention includes direct injection at a tissue site. Alternatively, an antisense nucleic acid molecule can be modified to target selected cells and then administered systemically. For example, for systemic administration, an antisense molecule can be modified such that it specifically binds to a receptor or an antigen expressed on a selected cell surface, e.g., by linking the antisense nucleic acid molecule to a peptide or an antibody which binds to a cell surface receptor or antigen. The antisense nucleic acid molecule can also be delivered to cells using the vectors described herein.

In yet another embodiment, the antisense nucleic acid molecule of the invention is an α-anomeric nucleic acid molecule. An α-anomeric nucleic acid molecule forms specific double-stranded hybrids with complementary RNA in which, contrary to the usual γ-units, the strands run parallel to each other (Gaultier et al., 1987). The antisense nucleic acid molecule can also comprise a 2′-o-methylribonucleotide (Inoue et al., 1987a) or a chimeric RNA-DNA analogue (Inoue et al., 1987b).

In still another embodiment, an antisense nucleic acid of the invention is a ribozyme. Ribozymes are catalytic RNA molecules with ribonuclease activity that are capable of cleaving a single-stranded nucleic acid, such as a mRNA, to which they have a complementary region. Thus, ribozymes (e.g., hammerhead ribozymes described in Haselhoff and Gerlach, 1988) can be used to catalytically cleave Alloiococcus otitidis mRNA transcripts to thereby inhibit translation of Alloiococcus otitidis mRNA. A ribozyme having specificity for an Alloiococcus otitidis-encoding nucleic acid can be designed based upon the nucleotide sequence of an Alloiococcus otitidis cDNA disclosed herein. For example, a derivative of a Tetrahymena L-19 IVS RNA can be constructed in which the nucleotide sequence of the active site is complementary to the nucleotide sequence to be cleaved in an Alloiococcus otitidis-encoding mRNA. See, e.g., Cech et al. U.S. Pat. No. 4,987,071 and Cech et al. U.S. Pat. No. 5,116,742 both incorporated herein in their entirety by reference. Altematively, Alloiococcus otitidis mRNA can be used to select a catalytic RNA having a specific ribonuclease activity from a pool of RNA molecules. See, e.g., Bartel and Szostak, 1993.

Alternatively Alloiococcus otitidis gene expression is inhibited by targeting nucleotide sequences complementary to the regulatory region of the Alloiococcus otitidis gene (e.g., the Alloiococcus otitidis gene promoter and/or enhancers) to form triple helical structures that prevent transcription of the Alloiococcus otitidis gene in target cells. (See generally, Helene, 1991; Helene et al., 1992; and Maher, 1992).

Alloiococcus otitidis gene expression is also inhibited using RNA interference (RNAi). This is a technique for post-transcriptional gene silencing (PTGS), in which target gene activity is specifically abolished with cognate double-stranded RNA (dsRNA). RNAi resembles in many aspects PTGS in plants and has been detected in many invertebrates including trypanosome, hydra, planaria, nematode and fruit fly (Drosophila melangnoste). It may be involved in the modulation of transposable element mobilization and antiviral state formation. RNAi in mammalian systems is disclosed in WO 00/63364, which is incorporated by reference herein in its entirety. Basically, dsRNA of at least about 600 nucleotides, homologous to the target is introduced into the cell and a sequence specific reduction in gene activity is observed.

C. ALLOIOCOCCUS OTITIDIS POLYPEPTIDES

In particular embodiments, the present invention provides isolated and purified Alloiococcus otitidis polypeptides. Preferably, an Alloiococcus otitidis polypeptide of the invention is a recombinant polypeptide. In certain embodiments, an Alloiococcus otitidis polypeptide of the present invention comprises the amino acid sequence that has at least 70% identity to the amino acid sequence of one of even numbered sequences set forth in SEQ ID NO: 2 through SEQ ID NO: 6650, a biological equivalent thereof, or a fragment thereof.

An Alloiococcus otitidis polypeptide according to the present invention encompasses a polypeptide that comprises: 1) the amino acid sequence shown in one of the even numbered sequences set forth in SEQ ID NO: 2 through SEQ ID NO: 6650); (2) functional and non-functional naturally occurring variants or biological equivalents of Alloiococcus otitidis polypeptides of in one of the even numbered sequences set forth in SEQ ID NO: 2 through SEQ ID NO: 6650; (3) recombinantly produced variants or biological equivalents of Alloiococcus otitidis polypeptides set out in one of the even numbered sequences set forth in SEQ ID NO: 2 through SEQ ID NO: 6650; (4) polypeptides isolated from organisms other than Alloiococcus otitidis (orthologs of Alloiococcus otitidis polypeptides).

A biological equivalent or variant of an Alloiococcus otitidis polypeptide according to the present invention encompasses 1) a polypeptide isolated from Alloiococcus otitidis, and 2) a polypeptide that contains substantial homology to an Alloiococcus otitidis polypeptide.

Biological equivalents or variants of Alloiococcus otitidis include both functional and non-functional Alloiococcus otitidis polypeptides. Functional biological equivalents or variants are naturally occurring amino acid sequence variants of an Alloiococcus otitidis polypeptide that maintain the ability to elicit an immunological or antigenic response in a subject. Functional variants will typically contain only conservative substitutions of one or more amino acids in one of the even numbered sequences set forth in SEQ ID NO: 2 through SEQ ID NO: 6650 or substitution, deletion or insertion of non-critical residues in non-critical regions of the polypeptide (e.g., not in regions containing antigenic determinants or protective epitopes).

The present invention further provides non-Alloiococcus otitidis orthologs of Alloiococcus otitidis polypeptides. Orthologs of Alloiococcus otitidis polypeptides are polypeptides that are isolated from non-Alloiococcus otitidis organisms and possess antigenic capabilities of the Alloiococcus otitidis polypeptide. Orthologs of an Alloiococcus otitidis polypeptide can readily be identified as comprising an amino acid sequence that is substantially homologous to one of the even numbered sequences set forth in set forth in SEQ ID NO: 2 through SEQ ID NO: 6650.

Modifications and changes can be made in the structure of a polypeptide of the present invention and still obtain a molecule having Alloiococcus otitidis antigenicity. For example, certain amino acids can be substituted for other amino acids in a sequence without appreciable loss of antigenicity. Because it is the interactive capacity and nature of a polypeptide that defines that polypeptide's biological functional activity, certain amino acid sequence substitutions can be made in a polypeptide sequence (or, of course, its underlying DNA coding sequence) and nevertheless obtain a polypeptide with like properties.

In making such changes, the hydropathic index of amino acids can be considered. The importance of the hydropathic amino acid index in conferring interactive biologic function on a polypeptide is generally understood in the art (Kyte & Doolittle, 1982). It is known that certain amino acids can be substituted for other amino acids having a similar hydropathic index or score and still result in a polypeptide with similar biological activity. Each amino acid has been assigned a hydropathic index on the basis of its hydrophobicity and charge characteristics. Those indices are: isoleucine (+4.5); valine (+4.2); leucine (+3.8); phenylalanine (+2.8); cysteine/cystine (+2.5); methionine (+1.9); alanine (+1.8); glycine (−0.4); threonine (−0.7); serine (−0.8); tryptophan (−0.9); tyrosine (−1.3); proline (−1.6); histidine (−3.2); glutamate (−3.5); glutamine (−3.5); aspartate (−3.5); asparagine (−3.5); lysine (−3.9); and arginine (−4.5).

It is believed that the relative hydropathic character of the amino acid residue determines the secondary and tertiary structure of the resultant polypeptide, which in turn defines the interaction of the polypeptide with other molecules, such as enzymes, substrates, receptors, antibodies, antigens, and the like. It is known in the art that an amino acid can be substituted by another amino acid having a similar hydropathic index and still obtain a functionally equivalent polypeptide. In such changes, the substitution of amino acids whose hydropathic indices are within ±2 is preferred, those within ±1 are particularly preferred, and those within ±0.5 are even more particularly preferred.

Substitution of like amino acids can also be made on the basis of hydrophilicity, particularly where the biologically functional equivalent polypeptide or peptide thereby created is intended for use in immunological embodiments. U.S. Pat. No. 4,554,101, incorporated herein by reference, states that the greatest local average hydrophilicity of a polypeptide, as governed by the hydrophilicity of its adjacent amino acids, correlates with its immunogenicity and antigenicity, i.e. with a biological property of the polypeptide.

As detailed in U.S. Pat. No. 4,554,101, the following hydrophilicity values have been assigned to amino acid residues: arginine (+3.0); lysine (+3.0); aspartate (+3.0±1); glutamate (+3.0±1); serine (+0.3); asparagine (+0.2); glutamine (+0.2); glycine (0); proline (−0.5±1); threonine (−0.4); alanine (−0.5); histidine (−0.5); cysteine (−1.0); methionine (−1.3); valine (−1.5); leucine (−1.8); isoleucine (−1.8); tyrosine (−2.3); phenylalanine (−2.5); tryptophan (−3.4). It is understood that an amino acid can be substituted for another having a similar hydrophilicity value and still obtain a biologically equivalent, and in particular, an immunologically equivalent polypeptide. In such changes, the substitution of amino acids whose hydrophilicity values are within ±2 is preferred, those that are within ±1 are particularly preferred, and those within ±0.5 are even more particularly preferred.

As outlined above, amino acid substitutions are generally therefore based on the relative similarity of the amino acid side-chain substituents, for example, their hydrophobicity, hydrophilicity, charge, size, and the like. Exemplary substitutions which take various of the foregoing characteristics into consideration are well known to those of skill in the art and include: arginine and lysine; glutamate and aspartate; serine and threonine; glutamine and asparagine; and valine, leucine and isoleucine (see Table 23, below). The present invention thus contemplates functional or biological equivalents of an Alloiococcus otitidis polypeptide as set forth above. TABLE 23 AMINO ACID SUBSTITUTIONS Original Exemplary Residue Residue Substitution Ala Gly; Ser Arg Lys Asn Gln; His Asp Glu Cys Ser Gln Asn Glu Asp Gly Ala His Asn; Gln Ile Leu; Val Leu Ile; Val Lys Arg Met Met; Leu; Tyr Ser Thr Thr Ser Trp Tyr Tyr Trp; Phe Val Ile; Leu

Biological or functional equivalents of a polypeptide are also prepared using site-specific mutagenesis. Site-specific mutagenesis is a technique useful in the preparation of second generation polypeptides, or biologically functional equivalent polypeptides or peptides, derived from the sequences thereof, through specific mutagenesis of the underlying DNA. As noted above, such changes can be desirable where amino acid substitutions are desirable. The technique further provides a capacity to prepare and test sequence variants, for example, incorporating one or more of the foregoing considerations, by introducing one or more nucleotide sequence changes into the DNA. Site-specific mutagenesis allows the production of mutants through the use of specific oligonucleotide sequences which encode the DNA sequence of the desired mutation, as well as a sufficient number of adjacent nucleotides, to provide a primer sequence of sufficient size and sequence complexity to form a stable duplex on both sides of the deletion junction being traversed. Typically, a primer of about 17 to 25 nucleotides in length is preferred, with about 5 to 10 residues on both sides of the site of the alteration of the sequence.

In general, the technique of site-specific mutagenesis is well known in the art. As will be appreciated, the technique typically employs a phage vector that can exist in both a single stranded and double stranded form. Typically, site-directed mutagenesis in accordance herewith is performed by first obtaining a single-stranded vector which includes within its sequence a DNA sequence which encodes all or a portion of the Alloiococcus otitidis polypeptide sequence selected. An oligonucleotide primer bearing the desired mutated sequence is prepared (e.g., synthetically). This primer is then annealed to the singled-stranded vector, and extended by the use of enzymes such as Escherichia coli polymerase I Klenow fragment, in order to complete the synthesis of the mutation-bearing strand. Thus, a heteroduplex is formed wherein one strand encodes the original non-mutated sequence and the second strand bears the desired mutation. This heteroduplex vector is then used to transform appropriate cells such as Escherichia coli cells and clones are selected which include recombinant vectors bearing the mutation. Commercially available kits come with all the reagents necessary, except the oligonucleotide primers.

An Alloiococcus otitidis polypeptide or polypeptide antigen of the present invention is understood to mean any Alloiococcus otitidis polypeptide comprising substantial sequence similarity, structural similarity and/or functional similarity to an Alloiococcus otitidis polypeptide comprising the amino acid sequence of one of the even numbered sequences set forth in SEQ ID NO: 2 through SEQ ID NO: 6650. In addition, an Alloiococcus otitidis polypeptide or polypeptide antigen of the invention is not limited to a particular source. Thus, the invention provides for the general detection and isolation of the polypeptides from a variety of sources.

It is contemplated in the present invention, that an Alloiococcus otitidis polypeptide may advantageously be cleaved into fragments for use in further structural or functional analysis, or in the generation of reagents such as Alloiococcus otitidis-related polypeptides and Alloiococcus otitidis-specific antibodies. This can be accomplished by treating purified or unpurified Alloiococcus otitidis polypeptides with a peptidase such as endoproteinase glu-C (Roche Diagnostics Corporation, Indianapolis, Ind.). Treatment with CNBr is another method by which peptide fragments may be produced from natural Alloiococcus otitidis polypeptides. Recombinant techniques also can be used to produce specific fragments of an Alloiococcus otitidis polypeptide.

In addition, the Applicants also contemplate that compounds sterically similar to a particular Alloiococcus otitidis polypeptide antigen, called peptidomimetics, may be formulated to mimic the key portions of the peptide structure. Peptidemimetics are peptide-containing molecules that mimic elements of protein secondary structure. (See, for example, Johnson et al., 1993.) The underlying rationale behind the use of peptide mimetics is that the peptide backbone of proteins exists chiefly to orient amino acid side chains in such a way as to facilitate molecular interactions, such as those of receptor and ligand.

Successful applications of the peptide mimetic concept have thus far focused on mimetics of β-turns within proteins. Likely β-turn structures within Alloiococcus otitidis proteins can be predicted by computer-based algorithms as discussed above. Once the component amino acids of the turn are determined, mimetics can be constructed to achieve a similar spatial orientation of the essential elements of the amino acid side chains, as discussed in Johnson et al., 1993.

Fragments of the Alloiococcus otitidis polypeptides are also included in the invention. A fragment is a polypeptide having an amino acid sequence that entirely is the same as a part, but not all, of the amino acid sequence. The fragment can comprise, for example, at least 7 or more (e.g., 8, 10 12, 14,16, 18, 20 or more) contiguous amino acids of an one of amino acid sequence selected from one of the even numbered sequences set forth in SEQ ID NO.: 2 through SEQ ID NO.: 6650. Fragments may be “freestanding” or comprised within a larger polypeptide of which they form a part or region, most preferably as a single, continuous region. In one embodiment, the fragments include at least one epitope of the mature polypeptide sequence. “Fusion protein” refers to a protein encoded by two, often unrelated, fused genes or fragments thereof. For example, fusion proteins comprising various portions of constant region of immunoglobulin molecules together with another human protein or part thereof have been described. In many cases, employing an immunoglobulin Fc region as a part of a fusion protein is advantageous for use in therapy and diagnosis resulting in, for example, improved pharmacokinetic properties (see, e.g., EP-A 0232 2621). On the other hand, for some uses it would be desirable to be able to delete the Fc part after the fusion protein has been expressed, detected and purified.

D. ALLOIOCOCCUS OTITIDIS POLYNUCLEOTIDE AND POLYPEPTIDE VARIANTS

“Variant” as the term is used herein, is a polynucleotide or polypeptide that differs from a reference polynucleotide or polypeptide respectively, but retains essential properties. A typical variant of a polynucleotide differs in nucleotide sequence from another, reference polynucleotide. Changes in the nucleotide sequence of the variant may or may not alter the amino acid sequence of a polypeptide encoded by the reference polynucleotide. Nucleotide changes may result in amino acid substitutions, additions, deletions, fusions and truncations in the polypeptide encoded by the reference sequence, as discussed below. A typical variant of a polypeptide differs in amino acid sequence from another, reference polypeptide. Generally, differences are limited so that the sequences of the reference polypeptide and the variant are closely similar overall and, in many regions, identical. A variant and reference polypeptide may differ in amino acid sequence by one or more substitutions, additions and deletions in any combination. A substituted or inserted amino acid residue may or may not be one encoded by the genetic code. A variant of a polynucleotide or polypeptide may be a naturally occurring such as an allelic variant, or it may be a variant that is not known to occur naturally. Non-naturally occurring variants of polynucleotides and polypeptides may be made by mutagenesis techniques or by direct synthesis.

“Identity,” as known in the art, is a relationship between two or more polypeptide sequences or two or more polynucleotide sequences, as determined by comparing the sequences. In the art, “identity” also means the degree of sequence relatedness between polypeptide or polynucleotide sequences, as the case may be, as determined by the match between strings of such sequences. “Identity” can be readily calculated by known methods, including but not limited to those described in (Computational Molecular Biology, Lesk, A. M., ed., Oxford University Press, New York, 1988; Biocomputing: Informatics and Genome Projects, Smith, D. W., ed., Academic Press, New York, 1993; Computer Analysis of Sequence Data, Part I, Griffin, A. M., and Griffin, H. G., eds., Humana Press, New Jersey, 1994; Sequence Analysis in Molecular Biology, von Heinje, G., Academic Press, 1987; and Sequence Analysis Primer, Gribskov, M. and Devereux, J., eds., M Stockton Press, New York, 1991; and Carillo, H., and Lipman, D., SIAM J. Applied Math., 48: 1073 (1988). Preferred methods to determine identity are designed to give the largest match between the sequences tested. Methods to determine identity are codified in publicly available computer programs. Preferred computer program methods to determine identity between two sequences include, but are not limited to, the GCG program package (Devereux, J., et al 1984), BLASTP, BLASTN, and FASTA (Altschul, S. F., et al., 1990. The BLASTX program is publicly available from NCBI and other sources (BLAST Manual, Altschul, S., et al., NCBI NLM NIH Bethesda, Md. 20894; Altschul, S., et al., 1990). The well-known Smith-Waterman algorithm may also be used to determine identity. (Smith, T. L. and Waterman, M. S., 1981).

By way of example, a polynucleotide sequence of the present invention may be identical to the reference sequence of one of the odd numbered sequences set forth in SEQ ID NO:1 through SEQ ID NO: 6649, that is be 100% identical, or it may include up to a certain integer number of nucleotide alterations as compared to the reference sequence. Such alterations are selected from the group consisting of at least one nucleotide deletion, substitution, including transition and transversion, or insertion, and wherein said alterations may occur at the 5′ or 3′ terminal positions of the reference nucleotide sequence or anywhere between those terminal positions, interspersed either individually among the nucleotides in the reference sequence or in one or more contiguous groups within the reference sequence. The number of nucleotide alterations is determined by multiplying the total number of nucleotides in one of the odd numbered sequences set forth in SEQ ID NO: 1 through SEQ ID NO: 6649 by the numerical percent of the respective percent identity (divided by 100) and subtracting that product from said total number of nucleotides in one of the odd numbered sequences set forth in SEQ ID NO: 1 through SEQ ID NO: 6649.

For example, the alterations in an isolated Alloiococcus otitidis polynucleotide comprising a polynucleotide sequence that has at least 70% identity to the nucleic acid sequence of one of the odd numbered sequences set forth in SEQ ID NO: 1 through SEQ ID NO: 6649; a degenerate variant thereof or a fragment thereof, wherein the polynucleotide sequence may include up to n_(n) nucleic acid alterations over the entire polynucleotide region of the nucleic acid sequence of one of the odd numbered sequences set forth in SEQ ID NO: 1 through SEQ ID NO: 6649, wherein n_(n) is the maximum number of alterations and is calculated by the formula: n _(n) ≦x _(n)−(x _(n) ·y), in which x_(n) is the total number of nucleic acids of one of the odd numbered sequences set forth in SEQ ID NO:1 through SEQ ID NO:6649 and y has a value of 0.70, wherein any non-integer product of x_(n) and y is rounded down to the nearest integer prior to subtracting such product from x_(n). Furthermore, y may also have a value of 0.80 for 80%, 0.85 for 85%, 0.90 for 90% 0.95 for 95%, etc.

Similarly, a polypeptide sequence of the present invention may be identical to the reference sequence of one of the even numbered sequences set forth in SEQ ID NO: 2 through SEQ ID NO: 6650, that is 100% identical, or it may include up to a certain integer number of amino acid alterations as compared to the reference sequence such that the percentage identity is less than 100%. Such alterations are selected from the group consisting of at least one amino acid deletion, substitution, including conservative and non-conservative substitution, or insertion, and wherein said alterations may occur at the amino- or carboxy-terminal positions of the reference polypeptide sequence or anywhere between those terminal positions, interspersed either individually among the amino acids in the reference sequence or in one or more contiguous groups within the reference sequence. The number of amino acid alterations for a given % identity is determined by multiplying the total number of amino acids in one of the even numbered sequences set forth in SEQ ID NO: 2 through SEQ ID NO: 6650 by the numerical percent of the respective percent identity (divided by 100) and then subtracting that product from said total number of amino acids in one of the even numbered sequences set forth in SEQ ID NO: 2 through SEQ ID NO: 6650, or: n _(a) ≦x _(a)−(x _(a) ·y), wherein n_(a) is the number of amino acid alterations, x_(a) is the total number of amino acids in one of the even numbered sequences set forth in SEQ ID NO: 2 through SEQ ID NO: 6650, and y is, for instance 0.70 for 70%, 0.80 for 80%, 0.85 for 85% etc., and wherein any non-integer product of x_(a) and y is rounded down to the nearest integer prior to subtracting it from x_(a). E. VECTORS, HOST CELLS AND RECOMBINANT ALLOIOCOCCUS OTITIDIS POLYPEPTIDES

In a preferred embodiment, the present invention provides expression vectors comprising ORF polynucleotides that encode Alloiococcus otitidis polypeptides. Preferably, the expression vectors of the present invention comprise ORF polynucleotides that encode Alloiococcus otitidis polypeptides comprising the amino acid residue sequence of one of the even numbered sequences set forth in SEQ ID NO: 2 through SEQ ID NO: 6650. More preferably, the expression vectors of the present invention comprise a polynucleotide comprising the nucleotide base sequence of one of the odd numbered sequences set forth in SEQ ID NO: 1 through SEQ ID NO: 6649. Even more preferably, the expression vectors of the invention comprise a polynucleotide operatively linked to a promoter. Still more preferably, the expression vectors of the invention comprise a polynucleotide operatively linked to a prokaryotic promoter. Alternatively, the expression vectors of the present invention comprise a polynucleotide operatively linked to an enhancer-promoter, that is, an eukaryotic promoter. The expression vectors further comprise a polyadenylation signal that is positioned 3′ of the codon encoding the carboxy-terminal amino acid and within a transcriptional unit of the encoded polypeptide.

Expression of proteins in prokaryotes is most often carried out in Escherichia coil with vectors containing constitutive or inducible promoters directing the expression of either fusion or non-fusion proteins. Fusion vectors add a number of amino acids to a protein encoded therein, usually to the amino terminus of the recombinant protein. Such fusion vectors typically serve three purposes: 1) to increase expression of recombinant protein; 2) to increase the solubility of the recombinant protein; and 3) to aid in the purification of the recombinant protein by acting as a ligand in affinity purification. Often, in fusion expression vectors, a proteolytic cleavage site is introduced at the junction of the fusion moiety and the recombinant protein to enable separation of the recombinant protein from the fusion moiety subsequent to purification of the fusion protein. Such enzymes, and their cognate recognition sequences, include Factor Xa, thrombin and enterokinase.

Typical fusion expression vectors include pGEX (Pharmacia Biotech Inc;), pMAL (New England Biolabs, Beverly; Mass.) and pRIT5 (Pharmacia, Piscataway, N.J.) which fuse glutathione S-transferase (GST), maltose E binding protein, or protein A, respectively, to the target recombinant protein.

In one embodiment, the coding sequence of the Alloiococcus otitidis polynucleotide is cloned into a pGEX expression vector to create a vector encoding a fusion protein comprising, from the N-terminus to the C-terminus, GST-thrombin cleavage site-Alloiococcus otitidis polypeptide. The fusion protein is purified by affinity chromatography using glutathione-agarose resin. Recombinant Alloiococcus otitidis polypeptide unfused to GST is recovered by cleavage of the fusion protein with thrombin.

Examples of suitable inducible non-fusion Escherichia coli expression vectors include pTrc (Amann et al., 1988) and pET I I d (Studier et al., 1990). Target gene expression from the pTrc vector relies on host RNA polymerase transcription from a hybrid trp-lac fusion promoter. Target gene expression from the pET II vector relies on transcription from a T7 gene1 lac fusion promoter mediated by a coexpressed viral RNA polymerase T7 genel. This viral polymerase is supplied by host strains BL21 (DE3) or HMS I 74(DE3) from a resident prophage harboring a T7 gene1 gene under the transcriptional control of the lacUV 5 promoter.

One strategy to maximize recombinant protein expression in Escherichia coli is to express the protein in a host bacterium with an impaired capacity to proteolytically cleave the recombinant protein. Another strategy is to alter the nucleic acid sequence of the nucleic acid to be inserted into an expression vector so that the individual codons for each amino acid are those preferentially utilized in Escherichia coli. Such alteration of nucleic acid sequences of the invention can be carried out by standard DNA mutagenesis or synthesis techniques.

In another embodiment, the Alloiococcus otitidis polynucleotide expression vector is a yeast expression vector. Examples of vectors for expression in a yeast such as S. cerevisiae include pYepSec I (Baldari, et al., 1987), pMFa (Kurjan and Herskowitz, 1982), pJRY88 (Schultz et al., 1987), and pYES2 (Invitrogen Corporation, San Diego, Calif.).

Alternatively, an Alloiococcus otitidis polynucleotide is expressed in insect cells using, for example, baculovirus expression vectors. Baculovirus vectors available for expression of proteins in cultured insect cells (e.g., Sf 9 or Sf 21 cells) include the pAc series (Smith et al., 1983) and the pVL series (Lucklow and Summers, 1989).

In yet another embodiment, a nucleic acid of the invention is expressed in mammalian cells using a mammalian expression vector. Examples of mammalian expression vectors include pCDM8 (Seed, 1987) and pMT2PC (Kaufman et al., 1987). When used in mammalian cells, the expression vector's control functions are often provided by viral regulatory elements.

For example, commonly used promoters are derived from polyoma, Adenovirus 2, cytomegalovirus (CMV) and Simian Virus 40 (SV40). For other suitable expression systems for both prokaryotic and eukaryotic cells see chapters 16 and 17 of Sambrook et al., “Molecular Cloning: A Laboratory Manual” 2nd, ed, Cold Spring Harbor Laboratory, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y., 1989, incorporated herein by reference.

In another embodiment, the recombinant mammalian expression vector is capable of directing expression of the nucleic acid preferentially in a particular cell type (e.g., tissue-specific regulatory elements are used to express the nucleic acid). Tissue-specific regulatory elements are known in the art. Non-limiting examples of suitable tissue-specific promoters include the albumin promoter (liver-specific; Pinkert et al., 1987), lymphoid-specific promoters (Calame and Eaton, 1988), in particular promoters of T cell receptors (Winoto and Baltimore, 1989) and immunoglobulins (Banerli et al., (1983); and Queen and Baltimore (1983)), neuron-specific promoters (e.g., the neurofilament promoter; Byrne and Ruddle, 1989), pancreas-specific promoters (Edlund et al., 1985), and mammary gland-specific promoters (e.g., milk whey promoter; U.S. Pat. No. 4, 873,316 and EP 264,166). Developmentally-regulated promoters are also encompassed, for example the murine hox promoters (Kessel and Gruss, 1990) and the α-fetoprotein promoter (Campes and Tilghman, 1989).

The invention further provides a recombinant expression vector comprising a DNA molecule encoding an Alloiococcus otitidis polypeptide cloned into the expression vector in an antisense orientation. That is, the DNA molecule is operatively linked to a regulatory sequence in a manner which allows for expression (by transcription of the DNA molecule) of an RNA molecule which is antisense to Alloiococcus otitidis mRNA. Regulatory sequences operatively linked to a nucleic acid cloned in the antisense orientation can be chosen which direct the continuous expression of the antisense RNA molecule in a variety of cell types, for instance viral promoters and/or enhancers, or regulatory sequences can be chosen which direct constitutive, tissue specific or cell type specific expression of antisense RNA. The antisense expression vector cari be in the form of a recombinant plasmid, phagemid or attenuated virus in which antisense nucleic acids are produced under the control of a high efficiency regulatory region, the activity of which can be determined by the cell type into which the vector is introduced.

Another aspect of the invention pertains to host cells into which a recombinant expression vector of the invention has been introduced. The terms “host cell” and “recombinant host cell” are used interchangeably herein. It is understood that such terms refer not only to the particular subject cell but also to the progeny or potential progeny of such a cell. Because certain modifications may occur in succeeding generations due to either mutation or environmental influences, such progeny may not, in fact, be identical to the parent cell, but are still included within the scope of the term as used herein. A host cell can be any prokaryotic or eukaryotic cell. For example, an Alloiococcus otitidis polypeptide can be expressed in bacterial cells such as Escherichia coli, insect cells, yeast or mammalian cells (such as Chinese hamster ovary cells (CHO), NIH3T3, PER C6, NSO or COS cells). Other suitable host cells are known to those skilled in the art.

Vector DNA can be introduced into prokaryotc or eukaryotic cells via conventional transformation, infection or transfection techniques. As used herein, the terms “transformation” and “transfection” are intended to refer to a variety of art-recongnized techniques for introducing foreign nucleic acid (e.g., DNA) into a host cell, including calcium phosphate or calcium chloride co-precipitation, DEAE-dextran-mediated transfection, lipofection, protoplast fusion, direct microinfection. Another recognized technique for introducing DNA into a host cell is “infection”, such as by adenovirus infection or electroporation. Suitable methods for transforming, infecting or transfecting host cells can be found in Sambrook, et al. (“Molecular Cloning: A Laboratory Manual” 2nd ed, Cold Spring Harbor Laboratory, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y., 1989), and other laboratory manuals.

The most widely used method is transfection mediated by either calcium phosphate or DEAE-dextran. Although the mechanism remains unclear, it is believed that the transfected DNA enters the cytoplasm of the cell by endocytosis and is transported to the nucleus. Depending on the cell type, up to 90% of a population of cultured cells can be transfected at any one time. Because of its high efficiency, transfection mediated by calcium phosphate or DEAE-dextran is the method of choice for experiments that require transient expression of the foreign DNA in large numbers of cells. Calcium phosphate-mediated transfection is also used to establish cell lines that integrate copies of the foreign DNA, which are usually arranged in head-to-tail tandem arrays into the host cell genome.

In the protoplast fusion method, protoplasts derived from bacteria carrying high numbers of copies of plasmid of interest are mixed directly with cultured mammalian cells. After fusion of the cell membranes (usually with polyethylene glycol), the contents of the bacteria are delivered into the cytoplasm of the mammalian cells and the plasmid DNA is transported to the nucleus. Protoplast fusion is not as efficient as transfection for many of the cell lines that are commonly used for transient expression assays, but it is useful for cell lines in which endocytosis of DNA occurs inefficiently. Protoplast fusion frequently yields multiple copies of the plasmid DNA tandemly integrated into the host chormosome.

The application of brief, high-voltage electric pulses (electroporation) to a variety of mammalian and plant cells leads to the formation of nanometer-sized pores in the plasma membrane. DNA is taken directly into the cell cytoplasm either through these pores or as a consequence of the redistribution of membrane components that accompanies closure of the pores. Electroporation can be extremely efficient and can be used both for transient expression of cloned genes and for establishment of cell lines that carry integrated copies of the gene of interest. Electroporation, in contrast to calcium phosphate-mediated transfection and protoplast fusion, frequently gives rise to cell lines that carry one, or at most a few, integrated copies of the foreign DNA.

Liposome transfection involves encapsulation of DNA and RNA within liposomes, followed by fusion of the liposomes with the cell membrane. The mechanism of how DNA is delivered into the cell is unclear, but transfection efficiencies can be as high as 90%.

Direct microinjection of a DNA molecule into nuclei has the advantage of not exposing DNA to cellular compartments such as low-pH endosomes. Microinjection therefore used primarily as a method to establish lines of cells that carry integrated copies of the DNA of interest.

The use of adenovirus as a vector for cell transfection is well known in the art. Adenovirus vector-mediated cell transfection has been reported for various cells (Stratford-Perricaudet, et al. 1992).

A host cell of the invention, such as a prokaryotic or eukaryotic host cell in culture, is used to produce (ie., express) one or more Alloiococcus otitidis polypeptides. Accordingly, the invention further provides methods for producing an Alloiococcus otitidis polypeptide using the host cells of the invention. In one embodiment, the method comprises culturing the host cell of invention (into which a recombinant expression vector encoding an Alloiococcus otitidis polypeptide has been introduced) in a suitable medium until the Alloiococcus otitidis polypeptide is produced. In another embodiment, the method further comprises isolating the Alloiococcus otitidis polypeptide from the medium or the host cell.

As used herein, a promoter is a region of a DNA molecule typically within about 100 nucleotide pairs in front of (upstream of) the point at which transcription begins (i.e., a transcription start site). That region typically contains several types of DNA sequence elements that are located in similar relative positions in different genes. As used herein, the term “promoter” includes what is referred to in the art as an upstream promoter region, a promoter region or a promoter of a generalized eukaryotic RNA Polymerase II transcription unit.

Another type of discrete transcription regulatory sequence element is an enhancer. An enhancer provides specificity of time, location and expression level for a particular encoding region (e.g., gene). A major function of an enhancer is to increase the level of transcription of a coding sequence in a cell that contains one or more transcription factors that bind to that enhancer. Unlike a promoter, an enhancer can function when located at variable distances from transcription start sites so long as a promoter is present.

As used herein, the phrase “enhancer-promoter” means a composite unit that contains both enhancer and promoter elements. An enhancer-promoter is operatively linked to a coding sequence that encodes at least one gene product. As used herein, the phrase “operatively linked” means that an enhancer-promoter is connected to a coding sequence in such a way that the transcription of that coding sequence is controlled and regulated by that enhancer-promoter. Means for operatively linking an enhancer-promoter to a coding sequence are well known in the art. As is also well known in the art, the precise orientation and location relative to a coding sequence whose transcription is controlled, is dependent inter alia upon the specific nature of the enhancer-promoter. Thus, a TATA box minimal promoter is typically located from about 25 to about 30 base pairs upstream of a transcription initiation site and an upstream promoter element is typically located from about 100 to about 200 base pairs upstream of a transcription initiation site. In contrast, an enhancer can be located downstream from the initiation site and can be at a considerable distance from that site.

An enhancer-promoter used in a vector construct of the present invention can be any enhancer-promoter that drives expression in a cell to be transfected. By employing an enhancer-promoter with well-known properties, the level and pattern of gene product expression can be optimized.

A coding sequence of an expression vector is operatively linked to a transcription termination region. RNA polymerase transcribes an encoding DNA sequence through a site where polyadenylation occurs. Typically, DNA sequences located a few hundred base pairs downstream of the polyadenylation site serve to terminate transcription. Those DNA sequences are referred to herein as transcription-termination regions. Those regions are required for efficient polyadenylation of transcribed messenger RNA (mRNA). Transcription-terminating regions are well known in the art. A preferred transcription-terminating region used in a vector construct of the present invention comprises a polyadenylation signal of SV40 or the protamine gene. The bGH polyadenylation signal is also suitable for use.

An expression vector comprises a polynucleotide that encodes an Alloiococcus otitidis polypeptide. Such a polypeptide is meant to include a sequence of nucleotide bases encoding an Alloiococcus otitidis polypeptide sufficient in length to distinguish the segment from a polynucleotide segment encoding a non-Alloiococcus otitidis polypeptide. A polypeptide of the invention can also encode biologically functional polypeptides or peptides, which have variant amino acid sequences, such as with changes selected, based on considerations such as the relative hydropathic score of the amino acids being exchanged. These variant sequences are those isolated from natural sources or induced in the sequences disclosed herein using a mutagenic procedure such as site-directed mutagenesis.

Preferably, an expression vector of the present invention comprises a polynucleotide that encodes a polypeptide comprising the amino acid residue sequence of one of even numbered sequences set forth in SEQ ID NO: 2 through SEQ ID NO:.6650 An expression vector can include an Alloiococcus otitidis polypeptide coding region itself of any of the Alloiococcus otitidis polypeptides noted above or it can contain coding regions bearing selected alterations or modifications in the basic coding region of such an Alloiococcus otitidis polypeptide. Alternatively, such vectors or fragments can encode larger polypeptides or polypeptides which nevertheless include the basic coding region. In any event, it should be appreciated that due to codon redundancy as well as biological functional equivalence, this aspect of the invention is not limited to the particular DNA molecules corresponding to the polypeptide sequences noted above.

Exemplary vectors include the mammalian expression vectors of the pCMV family including pCMV6b and pCMV6c (Chiron Corp., Emeryville Calif.). In certain cases, and specifically in the case of these individual mammalian expression vectors, the resulting constructs can require co-transfection with a vector containing a selectable marker such as pSV2neo. Via co-transfection into a dihydrofolate reductase-deficient Chinese hamster ovary cell line, such as DG44, clones expressing Alloiococcus otitidis polypeptides by virtue of DNA incorporated into such expression vectors can be detected.

A DNA molecule of the present invention can be incorporated into a vector by a number of techniques that are well known in the art. For instance, the vector pUC18 has been demonstrated to be of particular value in cloning and expression of genes. Likewise, the related vectors M13mp18 and M13mp19 can also be used in certain embodiments of the invention, in particular, in performing dideoxy sequencing.

An expression vector of the present invention is useful both as a means for preparing quantities of the Alloiococcus otitidis polypeptide-encoding DNA itself, and as a means for preparing the encoded polypeptide and peptides. It is contemplated that where Alloiococcus otitidis polypeptides of the invention are made by recombinant means, one can employ either prokaryotic or eukaryotic expression vectors as shuttle systems. In another aspect, the recombinant host cells of the present invention are prokaryotic host cells. Preferably, the recombinant host cells of the invention are bacterial cells of the DH5α strain of Escherichia coli. In general, prokaryotes are preferred for the initial cloning of DNA sequences and constructing the vectors useful in the invention. For example, Escherichia coli K12 strains can be particularly useful. Other microbial strains that can be used include Escherichia coli B, Escherichia coli W3110 (ATCC No. 273325) and Escherichia. coli _(x)1976 (ATCC No. 31537). Bacilli such as Bacillus subtilis, or other enterobacteriaceae such as Salmonella typhimurium or Serratia marcesans, and various Pseudomonas species can be used. These examples are, of course, intended to be illustrative rather than limiting.

In general, plasmid vectors containing replicon and control sequences that are derived from species compatible with the host cell are used in connection with these hosts. The vector ordinarily carries a replication site, as well as marking sequences that are capable of providing phenotypic selection in transformed cells. For example, Escherichia coli is transformed using pBR322, a plasmid derived from an Escherichia coli species (Bolivar, et al. 1977). pBR322 contains genes for ampicillin and tetracycline resistance and thus provides an easy means for identifying transformed cells. The pBR322 plasmid, or other microbial plasmid or phage, must also contain, or be modified to contain, promoters, which can be used by the microbial organism for expression of its own polypeptides.

Those promoters most commonly used in recombinant DNA construction include the β-lactamase (penicillinase) and lactose promoter systems (Chang, et al. 1978; Itakura, et al. 1977, Goeddel, et al. 1979; Goeddel, et al. 1980) and a tryptophan (TRP) promoter system (EP 0036776; Siebwenlist et al. 1980). While these are the most commonly used, other microbial promoters have been discovered and utilized, and details concerning their nucleotide sequences have been published, enabling a skilled worker to introduce functional promoters into plasmid vectors (Siebwenlist, et al. 1980).

In addition to prokaryotes, eukaryotic microbes such as yeast can also be used. Saccharomyces cerevisiase or common baker's yeast is the most commonly used among eukaryotic microorganisms, although a number of other strains are commonly available. For expression in Saccharomyces, the plasmid YRp7, for example, is commonly used (Stinchcomb, et al. 1979; Kingsman, et al. 1979; Tschemper, et al. 1980). This plasmid already contains the trpl gene that provides a selection marker for a mutant strain of yeast lacking the ability to grow in tryptophan, for example ATCC No. 44076 or PEP4-1 (Jones, 1977). The presence of the trpl lesion as a characteristic of the yeast host cell genome then provides an effective environment for detecting transformation by growth in the absence of tryptophan.

Suitable promoter sequences in yeast vectors include the promoters for 3-phosphoglycerate kinase (PGK) (Hitzeman, et al. 1980) or other glycolytic enzymes such as enolase, glyceraldehyde-3-phosphate dehydrogenase, hexokinase, pyruvate decarboxylase, phosphofructokinase, glucose-6-phosphate isomerase, 3-phosphoglycerate mutase, pyruvate kinase, triosephosphate isomerase, phosphoglucose isomerase, and glucokinase. In constructing suitable expression plasmids, the termination sequences associated with these genes are also introduced into the expression vector downstream from the sequences to be expressed to provide polyadenylation of the mRNA and termination. Other promoters, which have the additional advantage of transcription controlled by growth conditions are the promoter region for alcohol dehydrogenase 2, isocytochrome C, acid phosphatase, degradative enzymes associated with nitrogen metabolism, and the aforementioned glyceraldehyde-3-phosphate dehydrogenase, and enzymes responsible for maltose and galactose utilization. Any plasmid vector containing a yeast-compatible promoter, origin of replication, and termination sequences is suitable.

In addition to microorganisms, cultures of cells derived from multicellular organisms can also be used as hosts. In principle, any such cell culture is workable, whether from vertebrate or invertebrate culture. However, interest has been greatest in vertebrate cells, and propagation of vertebrate cells in culture (tissue culture) has become a routine procedure in recent years. Examples of such useful host cell lines are AtT-20, VERO, HeLa, NSO, PER C6, Chinese hamster ovary (CHO) cell lines, W138, BHK, COSM6, COS-7, 293 and MDCK cell lines. Expression vectors for such cells ordinarily include (if necessary) an origin of replication, a promoter located upstream of the gene to be expressed, along with any necessary ribosome binding sites, RNA splice sites, polyadenylation site, and transcriptional terminator sequences.

Where expression of recombinant Alloiococcus otitidis polypeptides is desired and a eukaryotic host is contemplated, it is most desirable to employ a vector, such as a plasmid, that incorporates a eukaryotic origin of replication. Additionally, for the purposes of expression in eukaryotic systems, one desires to position the Alloiococcus otitidis encoding sequence adjacent to and under the control of an effective eukaryotic promoter such as promoters used in combination with Chinese hamster ovary cells (CHO). To bring a coding sequence under control of a promoter, whether it is eukaryotic or prokaryotic, what is generally needed is to position the 5′ end of the translation initiation site of the proper translational reading frame of the polypeptide between about 1 and about 50 nucleotides 3′ of (downstream) the promoter chosen. Furthermore, where eukaryotic expression is anticipated, one would typically desire to incorporate an appropriate polyadenylation site into the transcriptional unit that includes the Alloiococcus otitidis polypeptide.

A transfected cell can be prokaryotic or eukaryotc. Preferably, the host cells of the invention are prokaryotic host cells. Where it is of interest to produce an Alloiococcus otitidis polypeptide, cultured prokaryotic host cells are of particular interest.

In yet another embodiment, the present invention contemplates a process or method of preparing Alloiococcus otitidis polypeptides comprising transfecting, transforming or infecting cells with a polynucleotide that encodes an Alloiococcus otitidis polypeptide to produce transformed host cells; and maintaining the transformed host cells under biological conditions sufficient for expression of the polypeptide. Preferably, the transformed host cells are prokaryotic cells. Alternatively, the host cells are eukaryotic cells. More preferably, the prokaryotic cells are bacterial cells of the DH5α strain of Escherichia coli. Even more preferably, the polynucleotide transfected into the transformed cells comprises the nucleic acid sequence of one of the odd numbered sequences set forth in SEQ ID NO: 1 through SEQ ID NO: 6649. Additionally, transfection is accomplished using an expression vector disclosed above. A host cell used in the process is capable of expressing a functional, recombinant Alloiococcus otitidis polypeptide.

Following transfection, the cell is maintained under culture conditions for a period of time sufficient for expression of an Alloiococcus otitidis polypeptide. Culture conditions are well known in the art and include ionic composition and concentration, temperature, pH and the like. Typically, transfected cells are maintained under culture conditions in a culture medium. Suitable media for various cell types are well known in the art. in a preferred embodiment, temperature is from about 20° C. to about 50° C., more preferably from about 30° C. to about 40° C. and, even more preferably about 37° C.

The pH is preferably from about a value of 6.0 to a value of about 8.0, more preferably from about a value of about 6.8 to a value of about 7.8 and, most preferably about 7.4. Osmolality is preferably from about 200 milliosmols per liter (mosm/L) to about 400 mosm/l and, more preferably from about 290 mosm/L to about 310 mosm/L. Other biological conditions needed for transfection and expression of an encoded protein are well known in the art.

Transfected cells are maintained for a period of time sufficient for expression of an Alloiococcus otitidis polypeptide. A suitable time depends inter alla upon the cell type used and is readily determinable by a skilled artisan. Typically, maintenance time is from about 2 to about 14 days.

Recombinant Alloiococcus otitidis polypeptide is recovered or collected either from the transfected cells or the medium in which those cells are cultured. Recovery comprises isolating and purifying the Alloiococcus otitidis polypeptide. Isolation and purification techniques for polypeptides are well known in the art and include such procedures as precipitation, filtration, chromatography, electrophoresis and the like.

F. ANTIBODIES IMMUNOREACTIVE WITH ALLOIOCOCCUS OTITIDIS POLYPEPTIDES

In still another embodiment, the present invention provides antibodies immunoreactive with Alloiococcus otitidis polypeptides. Preferably, the antibodies of the invention are monoclonal antibodies. Additionally, the Alloiococcus otitidis polypeptides comprise the amino acid residue sequence of one of the even numbered sequences set forth in SEQ ID NO: 2 through SEQ ID NO: 6650. Means for preparing and characterizing antibodies are well known in the art (see, e.g., Antibodies “A Laboratory. Manual”, E. Howell and D. Lane, Cold Spring Harbor Laboratory, 1988). Polyclonal antisera is obtained by bleeding an immunized animal into a glass or plastic container, incubating the blood at 25° C. for one hour, followed by incubating at 4° C. for 2-18 hours. The serum is then recovered by centrifugation.

Briefly, a polyclonal antibody is prepared by immunizing the animal with an immunogen comprising a polypeptide or polynucleotide of the present invention, and collecting antisera from that immunized animal. A wide range of animal species can be used for the production of antisera. Typically an animal used for production of anti-antisera is a rabbit, a mouse, a rat, a hamster or a guinea pig. Because of the relatively large blood volume of rabbits, a rabbit is a preferred choice for production of polyclonal antibodies.

As is well known in the art, a given polypeptide or polynucleotide may vary in its immunogenicity. It is often necessary therefore to couple the immunogen (e.g., a polypeptide or polynucleotide) of the present invention with a carrier. Exemplary and preferred carriers are keyhole limpet hemocyanin (KLH) and bovine serum albumin (BSA). Other albumins such as ovalbumin, mouse serum albumin or rabbit serum albumin can also be used as carriers.

Means for conjugating a polypeptide or a polynucleotide to a carrier protein are well known in the art and include glutaraldehyde, m-maleimidobencoyl-N-hydroxysuccinimide ester, carbodiimide and bis-biazotized benzidine.

The amount of immunogen used for the production of polyclonal antibodies varies inter alia, upon the nature of the immunogen as well as the animal used for immunization. A variety of routes can be used to administer the immunogen (subcutaneous, intramuscular, intradermal, intravenous and intraperitoneal). The production of polyclonal antibodies is monitored by sampling blood from the immunized animal at various points following immunization. When a desired level of immunogenicity is obtained, the immunized animal can be bled and the serum isolated and stored.

In another aspect, the present invention contemplates a process of producing an antibody immunoreactive with an Alloiococcus otitidis polypeptide comprising the steps of (a) transfecting recombinant host cells with a polynucleotide that encodes an Alloiococcus otitidis polypeptide; (b) culturing the host cells under conditions sufficient for expression of the polypeptide; (c) recovering the polypeptides; and (d) preparing the antibodies to the polypeptides. Preferably, the host cell is transfected with the polynucleotide of one of the odd numbered sequences set forth in SEQ ID NO: 1 through SEQ ID NO: 6649. Even more preferably, the present invention provides antibodies prepared according to the process described above.

A monoclonal antibody of the present invention is readily prepared through use of well-known techniques such as those exemplified in U.S. Pat. No. 4,196,265, herein incorporated by reference. Typically, the technique involves first immunizing a suitable animal with a selected antigen (e.g., a polypeptide or polynucleotide of the present invention) in a manner sufficient to provide an immune response. Rodents such as mice and rats are preferred animals. Spleen cells from the immunized animal are then fused with cells of an immortal myeloma cell. Where the immunized animal is a mouse, a preferred myeloma cell is a murine NS-1 myeloma cell.

The fused spleen/myeloma cells are cultured in a selective medium to select fused spleen/myeloma cells from the parental cells. Fused cells are separated from the mixture of non-fused parental cells, e.g., by the addition of agents that block the de novo synthesis of nucleotides in the tissue culture media. Exemplary and preferred agents are aminopterin, methotrexate, and azaserine. Aminopterin and methotrexate block de novo synthesis of both purines and pyrimidines, whereas azaserine blocks only purine synthesis. Where aminopterin or methotrexate is used, the media is supplemented with hypoxanthine and thymidine as a source of nucleotides. Where azaserine is used, the media is supplemented with hypoxanthine.

This culturing provides a population of hybridomas from which specific hybridomas are selected. Typically, selection of hybridomas is performed by culturing the cells by single-clone dilution in microtiter plates, followed by testing the individual clonal supernatants for reactivity with an antigen-polypeptide. The selected clones are then propagated indefinitely to provide the monoclonal antibody.

By way of specific example, to produce an antibody of the present invention, mice are injected intraperitoneally with between about 1-200 μg of an antigen comprising a polypeptide of the present invention. B lymphocyte cells are stimulated to grow by injecting the antigen in association with an adjuvant such as complete Freund's adjuvant (CFA; a non-specific stimulator of the immune response containing killed Mycobacterium tuberculosis). At some time (e.g., at least two weeks) after the first injection, mice are boosted by injection with a second dose of the antigen mixed with incomplete Freund's adjuvant (IFA; lacks the killed mycobacterium of CFA).

A few weeks after the second injection, mice are tail bled and the sera titered by immunoprecipitation against radiolabeled antigen. Preferably, the process of boosting and titering is repeated until a suitable titer is achieved. The spleen of the mouse with the highest titer is removed and the spleen lymphocytes are obtained by homogenizing the spleen with a syringe. Typically, a spleen from an immunized mouse contains approximately 5×10⁷ to 2×10⁸ lymphocytes.

Mutant lymphocyte cells known as myeloma cells are obtained from laboratory animals in which such cells have been induced to grow by a variety of well-known methods. Myeloma cells lack the salvage pathway of nucleotide biosynthesis. Because myeloma cells are tumor cells, they can be propagated indefinitely in tissue culture, and are thus denominated immortal. Numerous cultured cell lines of myeloma cells from mice and rats, such as murine NS-1 myeloma cells, have been established.

Myeloma cells are combined under conditions appropriate to foster fusion with the normal antibody-producing cells from the spleen of the mouse or rat injected with the antigen/polypeptide of the present invention. Fusion conditions include, for example, the presence of polyethylene glycol. The resulting fused cells are hybridoma cells. Like myeloma cells, hybridoma cells grow indefinitely in culture.

Hybridoma cells are separated from unfused myeloma cells by culturing in a selection medium such as HAT media (hypoxanthine, aminopterin, thymidine). Unfused myeloma cells lack the enzymes necessary to synthesize nucleotides from the salvage pathway because they are killed in the presence of aminopterin, methotrexate, or azaserine. Unfused lymphocytes also do not continue to grow in tissue culture. Thus, only cells that have successfully fused (hybridoma cells) can grow in the selection media.

Each of the surviving hybridoma cells produces a single antibody. These cells are then screened for the production of the specific antibody immunoreactive with an antigen/polypeptide of the present invention. Single cell hybridomas are isolated by limiting dilutions of the hybridomas. The hybridomas are serially diluted many times and, after the dilutions are allowed to grow, the supematant is tested for the presence of the monoclonal antibody. The clones producing that antibody are then cultured in large amounts to produce an antibody of the present invention in convenient quantity.

By use of a monoclonal antibody of the present invention, specific polypeptides and polynucleotide of the invention are identified as antigens. Once identified, those polypeptides and polynucleotide are isolated and purified by techniques such as antibody-affinity chromatography. In antibody-affinity chromatography, a monoclonal antibody is bound to a solid substrate and exposed to a solution containing the desired antigen. The antigen is removed from the solution through an immunospecific reaction with the bound antibody. The polypeptide or polynucleotide is then easily removed from the substrate and purified.

Additionally, examples of methods and reagents particularly amenable for use in generating and screening an antibody display library can be found in, for example, U.S. Pat. No. 5,223,409; WO 92/18619; WO 91/17271; WO 92/20791; WO 92/15679; WO 93/01288; WO 92/01047; WO 92/09690; WO 90/02809, which are incorporated herein in their entirety by reference.

Additionally, recombinant anti-Alloiococcus otitidis antibodies, such as chimeric and humanized monoclonal antibodies, comprising both human and non-human fragments, which are made using standard recombinant DNA techniques, are within the scope of the invention. Such chimeric and humanized monoclonal antibodies are produced by recombinant DNA techniques known in the art, for example using methods described in PCT/US86/02269; EP 184,187; EP 171,496; EP 173,494; WO 86/01533; U.S. Pat. No. 4,816,567; and EP 125,023.

An anti-Alloiococcus otitidis antibody (e.g., monoclonal antibody) is used to isolate Alloiococcus otitidis polypeptides by standard techniques, such as affinity chromatography or immunoprecipitation. An anti-Alloiococcus otitidis antibody facilitates the purification of a natural Alloiococcus otitidis polypeptide from cells and recombinantly produced Alloiococcus otitidis polypeptides expressed in host cells. Moreover, an anti-Alloiococcus otitidis antibody is used to detect Alloiococcus otitidis polypeptide (e.g., in a cellular lysate or cell supernatant) in order to evaluate the abundance of the Alloiococcus otitidis polypeptide. The detection of circulating fragments of an Alloiococcus otitidis polypeptide is used to identify Alloiococcus otitidis polypeptide turnover in a subject. Anti-Alloiococcus otitidis antibodies are used diagnostically to monitor protein levels in issue as part of a clinical testing procedure, e.g., to, for example, determine the efficacy of a given treatment regimen. Detection is facilitated by coupling (i.e., physically linking) the antibody to a detectable substance. Examples of detectable substances include various enzymes, prosthetic groups, fluorescent materials, luminescent materials, bioluminescent materials, and radioactive materials. Examples of suitable enzymes include horseradish peroxidase, alkaline phosphatase, P-galactosidase, or acetylcholinesterase; examples of suitable prosthetic group complexes include streptavidin/biotin and avidin/biotin; examples of suitable fluorescent materials include umbelliferone, fluorescein, fluorescein isothiocyanate, rhodamine, dichlorotriazinylarnine fluorescein, dansyl chloride or phycoerythrin; an example of a luminescent material includes luminol; examples of bioluminescent materials include luciferase, luciferin, and acquorin, and examples of suitable radioactive material include ¹²⁵I, ¹³¹I, ¹⁵S or ³H.

G. PHARMACEUTICAL AND IMMUNOGENIC COMPOSITIONS

In certain embodiments, the present invention provides pharmaceutical and immunogenic compositions comprising Alloiococcus otitidis polypeptides, and physiologically acceptable carriers. More preferably, the pharmaceutical and immunogenic compositions comprise Alloiococcus otitidis polypeptides comprising the amino acid residue sequence of one or more of the even numbered sequences set forth in SEQ ID NO: 2 through SEQ ID NO: 6650. In other embodiments, the pharmaceutical and immunogenic compositions of the invention comprise polynucleotides that encode Alloiococcus otitidis polypeptides, such as the polynucleotides comprising the nucleotide sequence of one of odd numbered sequences set forth in SEQ ID NO: 1 through SEQ ID NO: 6649, and physiologically acceptable carriers. Various tests may be used to assess the in vitro immunogenicity of the polypeptides of the invention. For example, an in vitro opsonic assay is conducted by incubating together a mixture of Alloiococcus otitidis cells, heat inactivated human serum containing specific antibodies to the polypeptide in question, and an exogenous complement source. Opsonophagocytosis proceeds during incubation of freshly isolated human polymorphonuclear cells (PMN) and the antibody/complement/Alloiococcal cell mixture. Bacterial cells that are coated with antibody and complement are killed upon opsonophagocytosis. Colony forming units (cfu) of surviving bacteria that escape from opsonophagocytosis are determined by plating the assay mixture. Titers are reported as the reciprocal of the highest dilution that gives ≧50% bacterial killing, as determined comparison to assay controls. The method described above is a modification of Gray's method (Gray, B. M., 1990).

A whole Alloiococcus otitidis cell ELISA assay is also used to assess in vitro immunogenicity and surface exposure of the polypeptide antigen, wherein the bacterial strain of interest (Alloiococcus otitidis) is coated onto a plate, such as 96 well plate, and test sera from an immunized animal is reacted with bacterial cells. If any antibody, specific for the test polypeptide antigen, is reactive with surface exposed epitope of the polypeptide antigen, it can be detected by standard methods known to one of skill in the art.

Any polypeptide demonstrating the desired in vitro activity is then tested in an in vivo animal challenge model. In certain embodiments, immunogenic compositions are used in the immunization of an animal (e.g., a mouse) by methods and routes of immunization known to those of skill in the art (e.g., intranasal, parenteral, intraperitoneal, intravenous, subcutaneous, etc.). Following immunization of the animal with a particular Alloiococcus otitidis immunogenic composition, the animal is challenged with Alloiococcus otitidis and assayed for resistance to Alloiococcus otitidis infection.

The Alloiococcus otitidis polynucleotides and polypeptides, and modulators of Alloiococcus otitidis polynucleotides and polypeptides, and anti-Alloiococcus otitidis antibodies (also referred to herein as “active compounds”) of the invention can be incorporated into pharmaceutical and immunogenic compositions suitable for administration to a subject, e.g., a human. Such compositions typically comprise the nucleic acid molecule, protein, modulator, or antibody and a pharmaceutically acceptable carrier. As used herein the language “pharmaceutically acceptable carrier” is intended to include any and all solvents, dispersion media, coatings, antibacterial and antifungal agents, isotonic and absorption delaying agents, and the like, compatible with pharmaceutical administration. The use of such media and agents for pharmaceutically active substances is well known in the art. Except insofar as any conventional media or agent is incompatible with the active compound, such media can be used in the compositions of the invention. Supplementary active compounds can also be incorporated into the compositions.

A pharmaceutical or immunogenic composition of the invention is formulated to be compatible with its intended route of administration. Examples of routes of administration include parenteral, (e.g., intravenous, intradermal, subcutaneous, intramuscular, and intraperitoneal), mucosal (e.g., oral, rectal, buccal, vaginal, intranasal, inhalation), and transdermal (topical). Solutions or suspensions used for parenteral, intradermal, or subcutaneous application can include the following components: a sterile diluents such as water for injection, saline solution, fixed oils, polyethylene glycols, glycerine, propylene glycol or other synthetic solvents; antibacterial agents such as benzyl alcohol or methyl parabens; antioxidants such as ascorbic acid or sodium bisulfite; chelating agents such as ethylenediaminetetraacetic acid; buffers such as acetates, citrates or phosphates and agents for the adjustment of tonicity such as sodium chloride or dextrose. pH can be adjusted with acids or bases, such as hydrochloric acid or sodium hydroxide. The parenteral preparation can be enclosed in ampoules, disposable syringes or multiple dose vials made of glass or plastic.

Pharmaceutical compositions suitable for injectable use include sterile aqueous solutions (where water soluble) or dispersions and sterile powders for the extemporaneous preparation of sterile injectable solutions or dispersion. For intravenous administration, suitable carriers include physiological saline, bacteriostatic water, Cremophor EL™(BASF, Parsippany, N.J.) or phosphate buffered saline (PBS). In all cases, the composition must be sterile and should be fluid to the extent that easy syringability exists. It must be stable under the conditions of manufacture and storage and must be preserved against the contaminating action of microorganisms such as bacteria and fungi. The carrier is a solvent or dispersion medium containing, for example, water, ethanol, polyol (for example, glycerol, propylene glycol, and liquid polyetheylene glycol, and the like), and suitable mixtures thereof. The proper fluidity is maintained, for example, by the use of a coating such as lecithin, by the maintenance of the required particle size in the case of dispersion and by the use of surfactants. Prevention of the action of microorganisms is achieved by various antibacterial and antifungal agents, for example, parabens, chlorobutanol, phenol, ascorbic acid,. thimerosal, and the like. In many cases, it is preferable to include isotonic agents, for example, sugars, polyalcohols such as manitol, sorbitol, and sodium chloride in the composition. Prolonged absorption of the injectable compositions is brought about by including in the composition an agent which delays absorption, for example, aluminum monostearate and gelatin.

Sterile injectable solutions are prepared by incorporating the active compound (e.g., an Alloiococcus otitidis polypeptide or anti-Alloiococcus otitidis antibody) in the required amount in an appropriate solvent with one or a combination of ingredients enumerated above, as required, followed by filtered sterilization. Generally, dispersions are prepared by incorporating the active compound into a sterile vehicle which contains a basic dispersion medium and the required other ingredients from those enumerated above. In the case of sterile powders for the preparation of sterile injectable solutions, the preferred methods of preparation are vacuum drying and freeze-drying which yields a powder of the active ingredient plus any additional desired ingredient from a previously sterile-filtered solution thereof.

Oral compositions generally include an inert diluent or an edible carrier. They can be enclosed in gelatin capsules or compressed into tablets. For the purpose of oral therapeutic administration, the active compound is incorporated with excipients and used in the form of tablets, troches, or capsules. Oral compositions are also prepared using a fluid carrier for use as a mouthwash, wherein the compound in the fluid carrier is applied orally and swished and expectorated or swallowed. Pharmaceutically compatible binding agents, and/or adjuvant materials can be included as part of the composition. The tablets, pills, capsules, troches and the like can contain any of the following ingredients, or compounds of a similar nature: a binder such as microcrystalline cellulose, gum tragacanth or gelatin; an excipient such as starch or lactose, a disintegrating agent such as alginic acid, Primogel, or corn starch; a lubricant such as magnesium stearate or Sterotes; a glidant such as colloidal silicon dioxide; a sweetening agent such as sucrose or saccharin; or a flavoring agent such as peppermint, methyl salicylate, or orange flavoring.

For administration by inhalation, the compounds are delivered in the form of an aerosol spray from pressured container or dispenser that contains a suitable propellant, e.g., a gas such as carbon dioxide, or a nebulizer. Systemic administration can also be by mucosal or transdermal means. For mucosal or transdermal administration, penetrants appropriate to the barrier to be permeated are used in the formulation. Such penetrants are generally known in the art, and include, for example, for mucosal administration, detergents, bile salts, and fusidic acid derivatives. Mucosal administration is accomplished through the use of nasal sprays or suppositories. For transdermal administration, the active compounds are formulated into ointments, salves, gels, or creams as generally known in the art.

The compounds is also prepared in the form of suppositories (e.g., with conventional suppository bases such as cocoa butter and other glycerides) or retention enemas for rectal delivery.

In one embodiment, the active compounds are prepared with carriers that will protect the compound against rapid elimination from the body, such as a controlled release formulation, including implants and microencapsulated delivery systems.

Biodegradable, biocompatible polymers can be used, such as ethylene vinyl acetate, polyanhydrides, polyglycolic acid, collagen, polyorthoesters, and polylactic acid. Methods for preparation of such formulations will be apparent to those skilled in the art. The materials are also obtained commercially from Alza Corporation (Palo Alto, Calif.) and Nova Pharmaceuticals, Inc. (Clifton, N.J.) Liposomal suspensions (including liposomes targeted to infected cells with monoclonal antibodies to viral antigens) are also used as pharmaceutically acceptable carriers. These are prepared according to methods known to those skilled in the art, for example, as described in U.S. Pat. No. 4,522,811, which is incorporated herein by reference.

It is especially advantageous to formulate oral or parenteral compositions in dosage unit form for ease of administration and uniformity of dosage. Dosage unit form as used herein refers to physically discrete units suited as unitary dosages for the subject to be treated; each unit containing a predetermined quantity of active compound calculated to produce the desired therapeutic effect in association with the required pharmaceutical carrier. The specification for the dosage unit forms of the invention are dictated by and directly dependent on the unique characteristics of the active compound and the particular therapeutic effect to be achieved, and the limitations inherent in the art of compounding such an active compound for the treatment of individuals.

Combination immunogenic compositions are provided by including two or more of the polypeptides of this invention. Multivalent immunogenic compositions directed against various bacteria responsible for causing otitis media comprise one or more of the polypeptides of this invention together with one or more known nontypable Haemophilus influenzae polypeptides, including, but not limited to, the P2, P4, P5, P6 and PCP proteins, and/or one or more known Moraxella catarrhalis polypeptides, including, but not limited to, the UspA1, UspA2, B1, C/D, E and 74 kDa proteins, and/or one or more known Streptococcus pneumoniae polypeptides and polysaccharide-protein conjugates, including, but not limited to, the currently available 23-valent pneumococcal capsular polysaccharide vaccine and the 7-valent pneumococcal polysaccharide-protein conjugate vaccine. One particularly preferred multivalent immunogenic composition comprises one or more of Alloiococcus otitidis polypeptides of the invention together with P4, P6, and UspA2 polypeptides.

The nucleic acid molecules of the invention are inserted into a variety of vectors and expression systems. A great variety of expression systems are used. Such systems include, among others, chromosomal, episomal and virus-derived systems, e.g., vectors derived from bacterial plasmids, attenuated bacteria such as Salmonella (U.S. Pat. No. 4,837,151) from bacteriophage, from transposons, from yeast episomes, from insertion elements, from yeast chromosomal elements, from viruses such as vaccinia and other poxviruses, sindbis, adenovirus, baculoviruses, papova viruses, such as SV40, fowl pox viruses, pseudorabies viruses and retroviruses, alphaviruses such as Venezuelan equine encephalitis virus (U.S. Pat. No. 5,643,576), nonsegmented negative-stranded RNA viruses such as vesicular stomatitis virus (U.S. Pat. No. 6,168,943), and vectors derived from combinations thereof, such as those derived from plasmid and bacteriophage genetic elements, such as cosmids and phagemids. The expression systems should include control regions that regulate as well as engender expression, such as promoters and other regulatory elements (such as a polyadenylation signal). Generally, any system or vector suitable to maintain, propagate or express polynucleotides to produce a polypeptide in a host may be used. The appropriate nucleotide sequence may be inserted into an expression system by any of a variety of well-known and routine techniques, such as, for example, those set forth in Sambrook et al., “Molecular Cloning: A Laboratory Manual” 2nd, ed, Cold Spring Harbor Laboratory, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y., 1989.

The nucleic acid molecules of the invention inserted into vectors as described above are also used to deliver the nucleic acid molecules to a subject by, for example, intravenous injection, local administration (see U.S. Pat. No. 5,328,470) or by stereotactic injection (see e.g., Chen et al., 1994). The pharmaceutical preparation for the administration of the nucleic acid molecules of the invention include, in addition to the nucleic molecules in an appropriate vector, an acceptable diluent, or can comprise a slow release matrix in which the nucleic acid molecule is embedded. Alternatively, where the complete nucleic acid moleculer is produced intact from recombinant cells, e.g. retroviral vectors, the pharmaceutical preparation includes one or more cells which produce the gene delivery system. The pharmaceutical compositions are included in a container, pack, or dispenser together with instructions for administration.

A pharmaceutically acceptable vehicle is understood to designate a compound or a combination of compounds entering into a pharmaceutical or immunogenic composition which does not cause side effects and which makes it possible, for example, to facilitate the administration of the active compound, to increase its life and/or its efficacy in the body, to increase its solubility in solution or alternatively to enhance its preservation. These pharmaceutically acceptable vehicles are well known and will be adapted by persons skilled in the art according to the nature and the mode of administration of the active compound chosen.

Immunogenic compositions may comprise appropriate adjuvants to modulate, shift and/or boost the immune response of the recipient to the immunogen. Such adjuvants are known to persons skilled in the art, such as those described in section H below.

A composition of the present invention is typically administered parenterally in dosage unit formulations containing standard, well-known nontoxic physiologically acceptable carriers, adjuvants, and vehicles as desired. The term parenteral as used herein includes intravenous, intramuscular, subcutaneous, intradermal, intraarterial injection, or infusion techniques, as well as other conventional techniques or routes described above.

Injectable preparations, for example sterile injectable aqueous or oleaginous suspensions, are formulated according to the known art using suitable dispersing or wetting agents and suspending agents. The sterile injectable preparation can also be a sterile injectable solution or suspension in a nontoxic parenterally acceptable diluent or solvent, for example, as a solution in 1,3-butanediol.

Among the acceptable vehicles and solvents that may be employed are water, Ringer's solution, and isotonic sodium chloride solution. In addition, sterile, fixed oils are conventionally employed as a solvent or suspending medium. For this purpose any bland fixed oil is employed including synthetic mono- or di-glycerides. In addition, fatty acids such as oleic acid find use in the preparation of injectables.

Preferred carriers include neutral saline solutions buffered with phosphate, lactate, Tris, and the like. When administering viral vectors, the vector is purified sufficiently to render it essentially free of undesirable contaminants, such as defective interfering adenovirus particles or endotoxins and other pyrogens such that it does not cause any untoward reactions in the individual receiving the vector construct. A preferred means of purifying the vector involves the use of buoyant density gradients, such as cesium chloride gradient centrifugation.

A carrier can also be a liposome. Means for using liposomes as delivery vehicles are well known in the art (see, e.g. Gabizon et al., 1990; and Ranade, V. V., 1989).

The immunogenic compositions of this invention also comprise a polynucleotide sequence of this invention operatively associated with a regulatory sequence that controls gene expression. The polynucleotide sequence of interest is engineered into an expression vector, such as a plasmid, under the control of regulatory elements which will promote expression of the DNA, that is, promoter and/or enhancer elements. In a preferred embodiment, the human cytomegalovirus immediate-early promoter/enhancer is used (U.S. Pat. No. 5,168,062). The promoter may be cell specific and permit increased expression of the polynucleotide only in predetermined cells.

The polynucleotide is introduced directly into the host either as “naked” DNA (U.S. Pat. No. 5,580,859) or formulated in compositions with agents which facilitate immunization, such as bupivicaine and other local anesthetics (U.S. Pat. No. 6,127,170).

In this polynucleotide immunization procedure, the polypeptides of the invention are expressed on a transient basis in vivo; no genetic material is inserted or integrated into the chromosomes of the host. This procedure is to be distinguished from gene therapy, where the goal is to insert or integrate the genetic material of interest into the chromosome. An assay is used to confirm that the polynucleotides administered by immunization do not rise to a transformed phenotype in the host (U.S. Pat. No. 6,168,918).

H. USES AND METHODS OF THE INVENTION

The Alloiococcus otitidis polynucleotides, polypeptides, polypeptide homologues, modulators, adjuvants, and antibodies described in this invention are used in methods of treatment, diagnostic assays particularly in disease identification, drug screening assays and monitoring of effects during clinical trials. The isolated polynucleotides of the invention are used to express Alloiococcus otitidis polypeptides (e.g., via a recombinant expression vector in a host cell or in gene therapy applications) and to detect Alloiococcus otitidis mRNA (e.g., in a biological sample). Moreover, the ant-Alloiococcus otitidis antibodies of the invention are used to detect and isolate an Alloiococcus otitidis polypeptide, particularly fragments of an Alloiococcus otitidis polypeptides present in a biological sample, and to modulate Alloiococcus otitidis polypeptide activity.

The invention provides immunogenic compositions comprising polypeptides having an amino acid sequence chosen from one or more of the even numbered sequences set forth in SEQ ID NO: 2 through SEQ ID NO: 6650, a biological equivalent thereof or a fragment thereof. The immunogenic composition may further comprise a pharmaceutically acceptable carrier, as outlined in section G.

In certain preferred embodiments, the immunogenic composition will comprise one or more adjuvants. As defined herein, an “adjuvant” is a substance that serves to enhance the immunogenicity of an “antigen” or the immunogenic compositions comprising a polypeptide antigens having an amino acid sequence chosen from one or more of even numbered sequences set forth in SEQ ID NO: 2 through SEQ ID NO: 6650. Thus, adjuvants are often given to boost the immune response and are well known to the skilled artisan. Preferred adjuvants to enhance effectiveness of the composition include, but are not limited to: (1) aluminum salts (alum), such as aluminum hydroxide, aluminum phosphate, aluminum sulfate, etc; (2) oil-in-water emulsion formulations (with or without other specific immunostimulating agents such as muramyl peptides (see below) or bacterial cell wall components), such as for example (a) MF59 (PCT Publ. No. WO90/14837), containing 5% Squalene, 0.5% Tween 80, and 0.5% Span 85 (optionally containing various amounts of MTP-PE (see below, although not required) formulated into submicron particles using a microfluidizer such as Model 110Y microfluidizer (Microfluidics, Newton, Mass.), (b) SAF, containing 10% Squalane, 0.4% Tween 80, 5% pluronic-blocked polymer L121, and thr-MDP (see below) either microfluidized into a submicron emulsion or vortexed to generate a larger particle size emulsion, and (c) Ribi™ adjuvant system (RAS), (Corixa, Hamilton, Mont.) containing 2% Squalene, 0.2% Tween 80, and one or more bacterial cell wall components from the group consisting of 3-O-deacylated monophosphorylipid A (MPL™) described in U.S. Pat. No. 4,912,094 (Corixa), trehalose dimycolate (TDM), and cell wall skeleton (CWS), preferably MPL+CWS (Detox™), (3) saponin adjuvants, such as Quil A or STIMULON™ QS-21 (Antigenics, Framingham, Mass.) (U.S. Pat. No. 5,057,540) may be used or particles generated therefrom such as ISCOMs (immunostimulating complexes); (4) bacterial lipopolysaccharides, synthetic lipid A analogs such as aminoalkyl glucosamine phosphate compounds (AGP), or derivatives or analogs thereof, which are available from Corixa, and which are described in U.S. Pat. No. 6,113,918; one such AGP is 2-[(R)-3-Tetradecanoyloxytetradecanoylamino]ethyl 2-Deoxy-4-O-phosphono-3-O-[(R)-3-tetradecanoyoxytetradecanoyl]-2-[(R)-3-tetradecanoyoxytetradecanoylamino]-b-D-glucopyranoside, which is also known as 529 (formerly known as RC529), which is formulated as an aqueous form or as a stable emulsion, synthetic polynucleotides such as oligonucleotides containing CpG motif(s) (U.S. Pat. No. 6,207,646); (5) cytokines, such as interleukins (e.g., IL-1, IL-2, IL-4, IL-5, IL-6, IL-7, IL-12, IL-15, IL-18, etc.), interferons (e.g., gamma interferon), granulocyte macrophage colony stimulating factor (GM-CSF), macrophage colony stimulating factor (M-CSF), tumor necrosis factor (TNF), etc; (6) detoxified mutants of a bacterial ADP-ribosylating toxin such as a cholera toxin (CT) either in a wild-type or mutant form, for example, wherein the glutamic acid at amino acid position is replaced by another amino acid, preferably a histidine, in accordance with published International patent Application number WO 00/18434, a pertussis toxin (PT, or an E. coli heat-labile toxin (LT), particularly LT-K63, LT-R72, CT-S109, PT-K9/G129; see, e.g., WO 93/13302 and WO 92/19265; and (7) other substances that act as immunostimulating agents to enhance the effectiveness of the composition.

As mentioned above, muramyl peptides include, but are not limited to, N-acetyl-muramyl-L-threonyl-D-isoglutamine(thr-MDP), N-acetyl-normuramyl-L-alanine-2-(1′-2′dipalmitoyl-snglycero-3-huydroxyphosphoryloxy)-ethylamine (MTP-PE), etc.

In another embodiment, the invention provides immunogenic compositions comprising a polynucleotide having a nucleotide sequence chosen from one or more of the odd numbered sequences set forth in SEQ ID NO: 1 through SEQ ID NO: 6649, wherein the polynucleotide is comprised in a recombinant expression vector. Preferably the vector is plasmid DNA. The polynucleotide may further comprise heterologous nucleotides, e.g., the polynucleotide is operatively linked to one or more gene expression regulatory elements, and further comprise one or more adjuvants. In a preferred embodiment, the immunogenic polynucleotide composition directs the expression of a neutralizing epitope of Alloiococcus otitidis.

Provided also are methods for immunizing a host against Alloiococcus otitidis infection. In a preferred embodiment, the host is human. Thus, a host or subject is administered an immunogenic amount of an immunogenic composition comprising a polypeptide having an amino acid sequence chosen from one or more of the even numbered sequences set forth in SEQ ID NO: 2 through SEQ ID NO: 6650, a biological equivalent thereof or a fragment thereof and a pharmaceutically acceptable carrier. An immunogenic amount of an immunogenic composition is determined by doing a dose response study in which subjects are immunized with gradually increasing amounts of the immunogenic composition and the immune response analyzed to determine the optimal dosage. Starting points for the study is inferred from immunization data in animal models. The dosage amount can vary depending upon specific conditions of the individual. The amount can be determined in routine trials by means known to those skilled in the art.

An “immunologically effective amount” of the immunogenic composition in an appropriate number of doses is administered to the subject to elicit an immune response. “Immunologically effective amount”, as used herein, means the administration of that amount to a mammalian host (preferably human), either in a single dose or as part of a series of doses, sufficient to at least cause the immune system of the individual treated to generate a response that reduces the clinical impact of the bacterial infection. Protection may be conferred by a single dose of the immunogenic composition, or may require the administration of several doses, in addition to booster doses at later times to maintain protection. This may range from a minimal decrease in bacterial burden to prevention of the infection. Ideally, the treated individuals will not exhibit the more serious clinical manifestations of the Alloiococcus otitidis infection. The dosage amount can vary depending upon specific conditions of the individual, such as age and weight. The amount can be determined in routine trials by means known to those skilled in the art.

I. DIAGNOSTIC ASSAYS

The invention provides methods for detecting the presence of an Alloiococcus otitidis polypeptide or Alloiococcus otitidis polynucleotide, or fragment thereof, in a biological sample. The method involves contacting the biological sample with a compound or an agent capable of detecting an Alloiococcus otitidis polypeptide or mRNA such that the presence of the Alloiococcus otitidis polypeptide/encoding nucleic acid molecule is detected in the biological sample. A preferred agent for detecting Alloiococcus otitidis mRNA or DNA is a labeled or labelable oligonucleotide probe capable of hybridizing to Alloiococcus otitidis mRNA or DNA. The nucleic acid probe can be, for example, a full-length Alloiococcus otitidis polynucleotide of one of the odd numbered sequences set forth in SEQ ID NO: 1 through SEQ ID NO: 6649, a complement thereof, or a fragment thereof, such as an oligonucleotide of at least 15, 30, 50, 100, 250 or 500 nucleotides in length and sufficient to specifically hybridize under stringent conditions to Alloiococcus otitidis mRNA or DNA. Alternatively, the sample can be contacted with an oligonucleotide primer of an Alloiococcus otitidis polynucleotide of one of the odd numbered sequences set forth in SEQ ID NO: 1 through SEQ ID No: 6649, a complement thereof, or a fragment thereof, in the presence of nucleotides and a polymerase, under conditions permitting primer extension.

A preferred agent for detecting an Alloiococcus otitidis polypeptide is a labeled or labelable antibody capable of binding to an Alloiococcus otitidis polypeptide of one of the even numbered sequences set forth in SEQ. ID. NO.: 2 through SEQ. ID. NO. 6650. Antibodies can be polyclonal, or more preferably, monoclonal. An intact antibody, or a fragment thereof (e.g., Fab or F(ab′)₂) can be used. The term “labeled or labelable,” with regard to the probe or antibody, is intended to encompass direct labeling of the probe or antibody by coupling (i.e., physically linking) a detectable substance to the probe or antibody, as well as indirect labeling of the probe or antibody by reactivity with another reagent that is directly labeled. Examples of indirect labeling include detection of a primary antibody using a fluorescently labeled secondary antibody and end-labeling of a DNA probe with biotin such that it are detected with fluorescently labeled streptavidin. The term “biological sample” is intended to include tissues, cells and biological fluids isolated from a subject, as well as tissues, cells and fluids present within a subject. That is, the detection method of the invention can be used to detect Alloiococcus otitidis mRNA, DNA or protein in a biological sample in vitro as well as in vivo. For example, in vitro techniques for detection of Alloiococcus otitidis mRNA include Northern hybridizations and in situ hybridizations. In vitro techniques for detection of Alloiococcus otitidis polypeptide include enzyme linked immunosorbent assays (ELISAs), Western blots, immunoprecipitations and immunofluorescence. Alternatively, Alloiococcus otitidis polypeptides can be detected in vivo in a subject by introducing into the subject a labeled anti-Alloiococcus otitidis antibody. For example, the antibody can be labeled with a radioactive marker whose presence and location in a subject can be detected by standard imaging techniques.

The polynucleotides according to the invention may also be used in analytical DNA chips, which allow sequencing, the study of mutations and of the expression of genes, and which are currently of interest given their very small size and their high capacity in terms of number of analyses.

The principle of the operation of these chips is based on molecular probes, most often oligonucleotides, which are attached onto a miniaturized surface, generally of the order of a few square centimeters. During an analysis, a sample containing fragments of a target nucleic acid to be analyzed, for example DNA or RNA labeled, for example, after amplification, is deposited onto the DNA chip in which the support has been coated beforehand with probes. Bringing the labeled target sequences into contact with the probes leads to the formation, through hybridization, of a duplex according to the rule of pairing defined by J. D.Watson and F.Crick. After a washing step, analysis of the surface of the chip allows the effective hybridizations to be located by means of the signals emitted by the labels tagging the target. A hybridization fingerprint results from this analysis which, by appropriate computer processing, will make it possible to determine information such as the presence of specific fragments in the sample, the determination of sequences and the presence of mutations.

The chip consists of a multitude of molecular probes, precisely organized or arrayed on a solid support whose surface is miniaturized. It is at the center of a system where other elements (imaging system, microcomputer) allow the acquisition and interpretation of a hybridization fingerprint.

The hybridization supports are provided in the form of flat or porous surfaces (pierced with wells) composed of various materials. The choice of a support is determined by its physicochemical properties, or more precisely, by the relationship between the latter and the conditions under which the support will be placed during the synthesis or the attachment of the probes or during the use of the chip. It is therefore necessary, before considering the use of a particular support, to consider characteristics such as its stability to pH, its physical strength, its reactivity and its chemical stability as well as its capacity to nonspecifically bind nucleic acids. Materials such as glass, silicon and polymers are commonly used. Their surface is, in a first step, called “functionalization”, made reactive towards the groups which it is desired to attach thereon. After the functionalization, so-called spacer molecules are grafted onto the activated surface. Used as intermediates between the surface and the probe, these molecules of variable size render unimportant the surface properties of the supports, which often prove to be problematic for the synthesis or the attachment of the probes and for the hybridization.

Among the hybridization supports, there may be mentioned glass which is used, for example, in the method of in situ synthesis of oligonucleotides by photochemical addressing developed by the company Affymetrix (E. L. Sheldon, 1993), the glass surface being activated by silane. Genosensor Consortium (P. Mérel, 1994) also uses glass slides carrying wells 3 mm apart, this support being activated with epoxysilane.

The probes according to the invention may be synthesized directly in situ on the supports of the DNA chips. This in situ synthesis may be carried out by photochemical addressing (developed by the company Affymax (Amsterdam, Holland) and exploited industrially by its subsidiary Affymetrix (United States)) or based on the VLSIPS (very large scale immobilized polymer synthesis) technology (S. P. A. Fodor et al., 1991) which is based on a method of photochemically directed combinatory synthesis and the principle of which combines solid-phase chemistry, the use of photolabile protecting groups and photolithography.

The probes according to the invention may be attached to the DNA chips in various ways such as electrochemical addressing, automated addressing or the use of probe printers (T. Livache et al., 1994; G. Yershov et al., 1996; and J. Derisi et al., 1996)

The revealing of the hybridization between the probes of the invention, deposited or synthesized in situ on the supports of the DNA chips, and the sample to be analyzed, may be determined, for example, by measurement of fluorescent signals, by radioactive counting or by electronic detection.

The use of fluorescent molecules such as fluorescein constitutes the most common method of labeling the samples. It allows direct or indirect revealing of the hybridization and allows the use of various fluorochromes.

Affymetrix currently provides an apparatus or a scanner designed to read its Gene Chip™ chips. It makes it possible to detect the hybridizations by scanning the surface of the chip in confocal microscopy (R. J. Lipshutz et al., 1995).

The nucleotide sequences according to the invention are also used in DNA chips to carry out the analysis of the expression of the Alloiococcus otitidis genes. This analysis of the expression of Alloiococcus otitidis genes is based on the use of chips where probes of the invention, chosen for their specificity to characterize a given gene, are present (D. J. Lockhart et al., 1996; D. D. Shoemaker et al., 1996). For the methods of analysis of gene expression using the DNA chips, reference may, for example, be made to the methods described by D. J. Lockhart et al. (1996) and Sosnowsky et al. (1997) for the synthesis of probes in situ or for the addressing and the attachment of previously synthesized probes. The target sequences to be analyzed are labeled and in general fragmented into sequences of about 50 to 100 nucleotides before being hybridized onto the chip. After washing as described, for example, by D. J. Lockhart et al. (1996) and application of different electric fields (Sosnowsky et al., 1997), the labeled compounds are detected and quantified, the hybridizations being carried out at least in duplicate. Comparative analyses of the signal intensities obtained with respect to the same probe for different samples and/or for different probes with the same sample, determine the differential expression of RNA or of DNA derived from the sample.

The nucleotide sequences according to the invention are, in addition, used in DNA chips where other nucleotide probes specific for other microorganisms are also present, and allow the carrying out of a serial test allowing rapid identification of the presence of a microorganism in a sample.

Accordingly, the subject of the invention is also the nucleotide sequences according to the invention, characterized in that they are immobilized on a support of a DNA chip.

The DNA chips, characterized in that they contain at least one nucleotide sequence according to the invention, immobilized on the support of the said chip, also form part of the invention.

The chips preferably contain several probes or nucleotide sequences of the invention of different length and/or corresponding to different genes so as to identify, with greater certainty, the specificity of the target sequences or the desired mutation in the sample to be analyzed.

Accordingly, the analyses carried out by means of primers and/or probes according to the invention, immobilized on supports such as DNA chips, make it possible, for example, to identify, in samples, mutations linked to variations such as intraspecies variations. These variations may be correlated or associated with pathologies specific to the variant identified and make it possible to select the appropriate treatment.

The invention thus comprises a DNA chip according to the invention, characterized in that it contains, in addition, at least one nucleotide sequence of a microorganism different from Alloiococcus otitidis, immobilized on the support of the said chip; preferably, the different microorganism is chosen from an associated microorganism, a bacterium of the Streptococcus family, and a variant of the species Alloiococcus otitidis.

The principle of the DNA chip as explained above, is also used to produce protein “chips” on which the support has been coated with a polypeptide or an antibody according to the invention, or arrays thereof, in place of the DNA. These protein “chips” make it possible, for example, to analyze the biomolecular interactions (BIA) induced by the affinity capture of target analytes onto a support coated, for example, with proteins, by surface plasma resonance (SPR). Reference may be made, for example, to the techniques for coupling proteins onto a solid support which are described in EP 524 800 or to the methods describing the use of biosensor-type protein chips such as the BIAcore-type technique (Pharmacia) (Arlinghaus et al., 1997 and Krone et al., 1997). These polypeptides or antibodies according to the invention, capable of specifically binding antibodies or polypeptides derived from the sample to be analyzed, are thus used in protein chips for the detection and/or the identification of proteins in samples. The said protein chips may in particular be used for infectious diagnosis and preferably contain, per chip, several polypeptides and/or antibodies of the invention of different specificity, and/or polypeptides and/or antibodies capable of recognizing microorganisms different from Alloiococcus otitidis.

Accordingly, the present invention also encompasses polypeptides and the antibodies according to the invention, characterized in that they are immobilized on a support, in particular, on a protein chip.

The protein chips, characterized in that they contain at least one polypeptide or one antibody according to the invention immobilized on the support of the said chip, also form part of the invention.

The invention comprises, in addition, a protein chip according to the invention, characterized in that it contains, in addition, at least one polypeptide of a microorganism different from Alloiococcus otitidis or at least one antibody directed against a compound of a microorganism different from Alloiococcus otitidis, immobilized on the support of the chip.

The invention also relates to a kit or set for the detection and/or the identification of bacteria belonging to the species Alloiococcus otitidis or to an associated microorganism, or for the detection and/or the identification of a microorganism characterized in that it comprises a protein chip according to the invention.

The present invention also provides a method for the detection and/or the identification of bacteria belonging to the species Alloiococcus otitidis or to an associated microorganism in a biological sample, characterized in that it uses a nucleotide sequence according to the invention.

The invention also encompasses kits for detecting the presence of an Alloiococcus otitidis polypeptide in a biological sample. For example, the kit comprises reagents such as a labeled or labelable compound or agent capable of detecting Alloiococcus otitidis polypeptide or mRNA in a biological sample; means for determining the amount of Alloiococcus otitidis polypeptide in the sample; and means for comparing the amount of Alloiococcus otitidis polypeptide in the sample with a standard. The compound or agent is packaged in a suitable container. The kit further comprises instructions for using the kit to detect Alloiococcus otitidis mRNA or protein.

In certain embodiments, detection involves the use of a probe/primer in a polymerase chain reaction (PCR) (see, e.g. U.S. Pat. No. 4,683,195 and U.S. Pat. No. 4,683,202), such as anchor PCR or RACE PCR, or, alternatively, in a ligation chain reaction (LCR). This method includes the steps of collecting a sample of cells from a patient, isolating nucleic acid (e.g., genomic, mRNA or both) from the cells of the sample, contacting the nucleic acid sample with one or more primers which specifically hybridize to an Alloiococcus otitidis polynucleotide under conditions such that hybridization and amplification of the Alloiococcus otitidis-polynucleotide (if present) occurs, and detecting the presence or absence of an amplification product, or detecting the size of the amplification product and comparing the length to a control sample.

J. TRANSGENIC ANIMALS

It is contemplated that in some instances the genome of a transgenic animal of the present invention will have been altered through the stable introduction of one or more of the Alloiococcus otitidis polynucleotide compositions described herein, either native, synthetically modified or mutated. As described herein, a “transgenic animal” refers to any non-human animal, preferably a non-human mammal (e.g. mouse, rat, rabbit, squirrel, hamster, rabbits, guinea pigs, pigs, micro-pigs, prairie, baboons, squirrel monkeys and chimpanzees, etc), bird or an amphibian, in which one or more cells contain a heterologous nucleic acid sequence introduced by way of human intervention, such as by transgenic techniques well known in the art. The nucleic acid is introduced into the cell, directly or indirectly, by introduction into a precursor of the cell, by way of deliberate genetic manipulation, such as by microinjection or by infection with a recombinant virus. The term genetic manipulation does not include classical crossbreeding, or in vitro fertilization, but rather is directed to the introduction of a recombinant DNA molecule. This molecule may be integrated within a chromosome, or it may be extrachromosomally replicating DNA.

The host cells of the invention are also used to produce non-human transgenic animals. The non-human transgenic animals are used in screening assays designed to identify infections or compounds, e.g., drugs, pharmaceuticals, etc., which are capable of ameliorating Alloiococcus otitidis symptoms or infections. For example, in one embodiment, a host cell of the invention is a fertilized oocyte or an embryonic stem cell into which an Alloiococcus otitidis polypeptide-coding sequence has been introduced. Such host cells are then used to create non-human transgenic animals in which exogenous Alloiococcus otitidis gene sequences have been introduced into their genome or homologous recombinant animals in which endogenous Alloiococcus otitidis gene sequences have been altered. Such animals are useful for studying the effects of an Alloiococcus otitidis polypeptide and for identifying and/or evaluating modulators of Alloiococcus otitidis polypeptide infectivity.

A transgenic animal of the invention is created by introducing an Alloiococcus otitidis polypeptide-encoding nucleic acid sequence into the male pronuclei of a fertilized oocyte, e.g., by microinjection, retroviral infection, and allowing the oocyte to develop in a pseudopregnant female foster animal. The human Alloiococcus otitidis cDNA sequence of one or more of the odd numbered sequences set forth in SEQ ID NO:1 through SEQ ID NO: 6649 can be introduced as a transgene into the genome of a non-human animal.

Moreover, a non-Alloiococcus otitidis homologue of the Alloiococcus otitidis gene can be isolated based on hybridization to the Alloiococcus otitidis cDNA (described above) and used as a transgene. Intronic sequences and polyadenylation signals can also be included in the transgene to increase the efficiency of expression of the transgene. A tissue-specific regulatory sequence(s) can be operably linked to the. Alloiococcus otitidis transgene to direct expression of an Alloiococcus otitidis polypeptide to particular cells. Methods for generating transgenic animals via embryo manipulation S and microinjection, particularly animals such as mice, have become conventional in the art and are described, for example, in U.S. Pat. Nos. 4,736,866 and 4,870, 009, U.S. Pat. No. 4,873,191 and in Hogan, 1986. Similar methods are used for production of other transgenic animals. A transgenic founder animal can be identified based upon the presence of the Alloiococcus otitidis transgene in its genome and/or expression of Alloiococcus otitidis mRNA in tissues or cells of the animals. A transgenic founder animal can then be used to breed additional animals carrying the transgene. Moreover, transgenic animals carrying a transgene encoding an Alloiococcus otitidis polypeptide can further be bred to other transgenic animals carrying other transgenes.

In another embodiment, transgenic non-human animals can be produced which contain selected systems that allow for regulated expression of the transgene. One example of such a system is the cre/loxP recombinase system of bacteriophage PL. For a description of the cre/loxP recombinase system, see, e.g., Lakso et al., 1992. Another example of a recombinase system is the FLP recombinase system of Saccharomyces cerevisiae (O'Gon-nan et al., 1991). If a cre/loxP recombinase system is used to regulate expression of the transgene, animals containing transgenes encoding both the Cre recombinase and a selected protein are required. Such animals can be provided through the construction of “double” transgenic animals, e.g., by mating two transgenic animals, one containing a transgene encoding a selected protein and the other containing a transgene encoding a recombinase.

Clones of the non-human transgenic animals described herein can also be produced according to the methods described in Wilmut et al., 1997, and PCT International Publication Nos. WO 97/07668 and WO 97/07669. In brief, a cell, e.g., a somatic cell, from the transgenic animal can be isolated and induced to exit the growth cycle and enter G_(o) phase. The quiescent cell can then be fused, e.g., through the use of electrical pulses, to an enucleated oocyte from an animal of the same species from which the quiescent cell is isolated. The reconstructed oocyte is then cultured such that it develops to morula or blastocyst and then transferred to pseudopregnant female foster animal. The offspring borne of this female foster animal will be a clone of the animal from which the cell, e.g., the somatic cell, is isolated.

All patents and publications cited herein are hereby incorporated by reference.

K. EXAMPLES

The following examples are carried out using standard techniques, which are well known and routine to those of skill in the art, except where otherwise described in detail. The following examples are presented for illustrative purposes only, and should not be construed in any way limiting the scope of this invention.

Example 1 Confirmation of the Identity of the Alloiococcus Otitidis 1104-92 Isolate

An Alloiococcus otitidis isolate designated 1104-92 was obtained from Dr. Richard Facklam of the Centers for Disease Control and Prevention in Atlanta. It was isolated from the middle ear fluid of a child in the Atlanta, Ga. area. It was confirmed to be Alloiococcus otitidis by comparing it to the type strain, ATCC51267, obtained from the American Type Culture Collection (Aguirre, 1992 #1). Both the 1104-92 isolate and the type strain were characterized as Gram positive cocci. Both grow on Columbia agar supplemented with 5% yeast extract, 0.5% polysorbate 80 (Tween 80), and 0.7% phospatidyl choline when incubated at 37° C. On this medium, both strains form slow growing small white colonies that require nearly two days to be easily observed with the naked eye. Both are sensitive to lysis by hen egg white lysozyme and Streptococcus globisporus mutanolysin. Both grow in the presence of 2% sodium azide. Both are killed by incubation at 55° C. for 30 minutes. The 1104-92 isolate was subjected to polymerase chain reaction (PCR) identification based on its 16s rRNA gene. This was done using two of the primers specified by Aguirre and Collins (Aguirre, 1992 #2). The antisense primer used was ATCTTCCTGCTTGCAGGAAGAGG (Seq. ID No.: 6653) and the sense primer was ACGCTTCATCTCTGAAGCTAGC (Seq. ID No.6652). PCR confirmed that the 1104-92 isolate was a strain of Alloiococcus otitidis. Thus by multiple criteria, the 1104-92 strain was confirmed to be an isolate of Alloiococcus otitidis.

Example 2 Storage, Growth, and Harvest of Alloiococcus Otitidis 1104-92 Isolate for the Isolation of Dna

The Alloiococcus otitidis isolate 1104-92 was stored at −70° C. in Todd-Hewlett broth containing 40% glycerol. A small portion of the frozen stock was streaked onto the agar medium described in Example 1 and incubated at 37° C. for two days. The growth from the plate was swabbed into a 17×100 cm tube containing 6 ml of a serum-free broth medium. This broth medium was prepared with 30 g Todd-Hewlett medium, 5 g yeast extract, 10 ml polysorbate 80 (Tween 80), and 1 liter distilled water. This medium was sterilized by autoclaving for 35 minutes. The bacteria were incubated aerobically without shaking in an aerobic incubator at 37° C. for two days. The tube containing the growing bacteria was then shaken to resuspend the bacteria and added to a liter of the same medium in a Fernbach flask. This flask, in turn, was incubated aerobically for three days without shaking. The bacteria were harvested by first swirling the flask to suspend the bacteria and then low speed centrifugation at about 5,000×g for 30 minutes. The pellet of bacteria was washed by resuspending it in 10 to 15 mL of phosphate buffered saline (PBS), and centrifuging the suspension at about 8,000×g for 20 minutes. The pellet of bacteria was retained and stored frozen at −20° C. The yield of wet bacterial pellet was typically about 1 g per liter of broth.

Example 3 Preparation of Alloiococcus Otitidis Genomic Dan

To prepare genomic DNA, 0.95 g frozen pellet of bacteria was defrosted and suspended in 10 mL of PBS containing 1 mM MgCl₂. The bacteria were killed by incubating the suspension at 55° C. for 20 minutes. The suspension was allowed to cool before adding 25 μl of a 10 mg/mL stock of hen egg white lysozyme and 50 μL of a 25,000 unit/mL stock of Streptococcus globisporus mutanolysin to the suspension. It was then incubated for one hour at 37° C. Then 50 μl of a 10 mg/mL stock of RNase was added and the suspension incubated an additional hour at 37° C. After these incubations, sodium dodecylsulfate (SDS) was added to a final concentration of 0.3% (0.3 mL of a 10% stock). This was followed by the addition of 0.3 mL of a 1 mg/mL stock of proteinase K The suspension was then incubated for two hours at 37° C. After this time, an equal volume of water saturated phenol/chloroform/isopropyl (25:24:1) was added to the digested suspension and gently mixed. The upper aqueous layer was retained after a low speed centrifugation and 2.5 volumes of ethanol were added and the tube gently inverted to mix. The DNA was then spooled out on a glass rod and allowed to air dry.

The DNA at this stage still contained obvious impurities and needed further purification. The DNA dried on the glass rod was soaked in 70% ethanol to remove excess phenol and air-dried once again. It was then suspended in 2 ml of Tris-EDTA buffer to which 2 μl of RNase cocktail was added and incubated at room temperature for 75 minutes. Then 100 μl of protease, 100 μl SDS and 40 μl of 100 mM CaCl₂ were added and the suspension incubated for 3.5 hours. An equal volume of chloroform was added, gently mixed, and then centrifuged at a low speed. The aqueous layer was collected and re-extracted with the phenol, chloroform, and isopropyl alcohol reagent. In turn, the aqueous layer was extracted with chloroform. At this point, 3 M sodium acetate was added to the aqueous phase collected form the last extraction and then 3.75 ml of ethanol was added and gently mixed. The DNA was spooled out, soaked in 70% ethanol and allowed to air-dry. The DNA was finally suspended in 2 ml of Tris-EDTA buffer. Based on absorption at 260 nm, the final yield of DNA was 482 μg of DNA. The DNA was confirmed to be that of Alloiococcus otitidis by the PCR method described in example 1. This DNA was submitted for sequencing. The sequences of all the ORFs were obtained as described in Examples 4 and 5 below, and are set forth in odd numbered sequence listings, Seq. ID No. 1 through Seq. ID No. 6649. The sequence of the entire Alloiococcus otitidis genome is set forth in Seq. ID No: 6651.

Example 4 Cloning and Sequencing of the Alloiococcus Otitidis Genome

This invention provides nucleotide sequences of the genome of Alloiococcus otitidis, which thus comprises a DNA sequence library of Alloiococcus otitidis genomic DNA. The description that follows provides nucleotide sequences of Alloiococcus otitidis, and also describes how the sequences were obtained and how ORFs (Open Reading Frames) and protein-coding sequences were identified.

To construct a library, genomic DNA was hydrodynamically sheared in an HPLC and then separated on a standard 1% agarose gel. A fraction corresponding to 3000-3500 bp in length was excised from the gel and purified by the GeneClean™ procedure (BIO101, Inc.).

The purified DNA fragments were then blunt-ended using T4 DNA polymerase. The blunt-ended DNA was then ligated to unique BstX1-linker adapters. These linkers are complementary to the pGTC vector, while the overhang is not self-complementary. Therefore, the linkers will not concatermerize nor will the cut-vector religate itself easily. The liner-adapted inserts were separated from the unincorporated linkers on a 1% agarose gel and again purified using GeneClean. The linker-adapted inserts were then ligated to BstX1-cut vector to construct “shotgun” subclone libraries.

Only major modifications to the standard protocols are highlighted. Briefly, the library was transformed into DH10B competent cells (Gibco/BRL, DH5a transformation protocol). Transformed cells were detected by plating onto antibiotic plates containing ampicillin. The plates were incubated overnight at 37° C. Transformant clones were then selected for sequencing. The cultures were grown overnight at 37° C. DNA was purified using a silica bead DNA preparation (Egelstein, 1996) method. In this manner, 25 mg of DNA was obtained per clone.

These purified DNA samples were then sequenced using ABI dye-terminator chemistry. All subsequent steps were based on sequencing by automated DNA sequencing methods. The ABI dye terminator sequence reads were run on MegaBace™ 10000 (Amersham) machines and the data transferred to UNIX based computers. Base calls and quality scores were determined using the PHRED software program (Ewing et al., 1998, Genome Res. 8: 175-185; Ewing and Green, 1998, Genome Res. 8:685-734). Reads were assembled using PHRAP (P. Green, Abstracts of DOE Human Genome Program Contractor-Grantee Workshop V, Jan.1996, p 157) with default program parameters and quality scores.

To identify Alloiococcus otitidis genome encoded polypeptides, the complete genomic sequence of Alloiococcus otitidis was analyzed essentially as follows: First, all possible stop-to-stop open reading frames (ORFs) greater than or equal to 222 nucleotides in all three reading frames were translated into amino acid sequences.

Second, the identified ORFs were analyzed for homology to known protein sequences. Third, the coding potential of non-homologous sequences was evaluated with the GeneMark™ software program (Borodovsky and Mcininch, 1993, Comp. Chem. 17:123).

Example 5 Bioinformatics and Gene Mining of Alloiococcus Otitidis

The genomic sequence of Alloiococcus otitidis was examined for suitable open reading frames. ORFs were determined in the following manner. An ORF was defined as having one of three potential start site codons, ATG, GTG, or TTG and one of three potential stop codons, TAA, TAG, TGA. The Applicants used a unique set of three ORF finder algorithms: GLIMMER™ (Salzberg et al., 1998), GeneMark™ (Lukashin and Borodovsky, 1998) and Applicants' assignee's own program to enhance the efficiency for finding “all” ORFs. In order to evaluate the accuracy of the ORFs determined, a program developed by Applicants' assignee called DiCTion was employed that uses a discrete mathematical cosine function to assign a score for each ORF. An ORF with a DiCTion score >1.5 was considered to have a high probability of encoding a protein product. The minimum length of an ORF predicted by the three ORF finders was set to 225 nucleotides (including stop codon) which would encode a protein of 74 amino acids. An in-house graphical analysis program developed by Applicants' assignee also allowed the Applicants to see all six reading frames and the location of the predicted ORFs relative to the genomic sequence. This helped to eliminate those ORFs that have large overlaps with other ORFs, although there are known cases of ORFs being totally embedded within other ORFs (Loessner et al., 1999; Hernandez-Sanchez et al., 1998).

The initial annotation of the Alloiococcus otitidis ORFs was performed using the BLAST (v. 2.0) Gapped search algorithm, BlastP, to identify homologous sequences (Altschul et al., 1997). A cutoff ‘e’ value of anything <e⁻¹⁰ was considered significant. Other search algorithms such as FASTA or PSI-BLAST were used as needed. The non-redundant protein sequence database used for the homology searches consisted of GenBank, SWISS-PROT, PIR, and TREMBL database sequences. ORFs with a BlastP result of >e⁻¹⁰ were considered to be unique to Alloiococcus otitidis.

A keyword search of the entire BLAST results was carried out using known or suspected target genes (those that encode polypeptide candidates for inclusion in immunogenic compositions) as well as words that identified the location of a protein or function.

Several parameters are used to determine partitioning of the predicted proteins. Proteins destined for translocation across the cytoplasmic membrane encode a leader signal (also called signal sequence) composed of a central hydrophobic region flanked at the N-terminus by positively charged residues (Pugsley, 1993). A program called SignalP identifies signal peptides and their cleavage sites (Nielsen et al., 1997). To predict protein localization in bacteria, the software PSORT has been used (Nakai and Kanehisa, 1991). This program uses a neural net algorithm to predict localization of proteins to the ‘cytoplasm', ‘periplasm’, and ‘cytoplasmic membrane’ for Gram-positive bacteria as well as ‘outer membrane’ for Gram-negative bacteria. Transmembrane (TM) domains of proteins have been detected using the software program TopPred2 (Cserzo et al., 1997).

The Hidden Markov Model (HMM) Pfam database of multiple alignments of protein domains or conserved protein regions (Sonnhammer et al., 1997) was used to identify Alloiococcus otitidis proteins that may belong to an existing protein family. Keyword searching of this output was used to help identify additional candidate polypeptides that may have been missed by the BLAST search criteria. Additional HMM models were developed by Applicants' assignee. A computer algorithm, called HMM Lipo, was developed internally to predict lipoproteins using 131 biologically proven bacterial lipoproteins. This training set was generated from experimentally proven prokaryotic lipoproteins. The protein sequence from the start of the protein to the cysteine amino acid plus the next two additional amino acids was used to generate the HMM. Using approximately 70 known prokaryotic proteins containing the LPXTG cell wall sorting signal, a HMM (Eddy, 1996), was developed to predict cell wall proteins that are anchored to the peptidoglycan layer (Mazmanian et al., 1999; Navarre and Schneewind, 1999). The model used not only the LPXTG sequence, but also included two features of the downstream sequence, the hydrophobic transmembrane domain and the positively charged carboxy terminus. There are also a number of proteins that interact, non-covalently, with the peptidoglycan layer and are distinct from the LPXTG protein class described above. These proteins seem to have a consensus sequence at their carboxy terminus (Koebnik, 1995). The Applicants also have developed and used a HMM of this region to identify any Alloiococcus otitidis that may fall into this class of proteins.

The proteins encoded by Alloiococcus otitidis identified ORFs were also evaluated for other useful characteristics. A tandem repeat finder (Benson, 1999) identified ORFs containing repeated DNA sequences such as those found in MSCRAMMs (Foster and Hook, 1998) and phase variable surface proteins of Neisseria meningitidis (Parkhill et al., 2000). Proteins that contain the Arg-Gly-Asp (RGD) attachment motif, together with integrins that serve as their receptor, constitute a major recognition system for cell adhesion. RGD recognition is one mechanism used by microbes to gain entry into eukaryotic tissues (Stockbauer et al., 1999; lsberg and Tran Van Nhieu, 1994). However, not all RGD containing proteins mediate cell attachment. It has been shown that RGD-containing peptides with a proline at the carboxy end (RGDP) are inactive in cell attachment assays (Pierschbacher and Ruoslahti, 1987) and were excluded from consideration. The Geanfammer software was used to cluster proteins into homologous families (Park and Teichmann, 1998). Preliminary analysis of the family classes has provided novel ORFs within a polypeptide candidate cluster, as well as defining potential protein function.

Example 6 Proteomics

Two strategies for identifying surface exposed proteins on microorganisms are used to identify surface exposed proteins on Alloiococcus otitidis. The first involves digesting of the surface of live organisms with protease and analyzing the released proteins. The second involves the purification of cellular membrane in a way that preserves the interaction of proteins that normally associate with the membrane. Both techniques revolve around the use of mass spectroscopy to identify the proteins that are detected but otherwise differ substantially.

In the first strategy, cells are treated with proteolytic enzymes in isotonic solution without substantial cell lysis. Experimentally, the cells are washed and suspended in an isotonic glycerol solution of neutral pH. A reductant, dithiothreitol, is first added to cleave the protein disulfide linkages and then iodoacetamide is added to alkylate the exposed cysteine thiols. The objective of this step is to break up the secondary and tertiary structure of the surface proteins. Porcine trypsin is then added and the cells are incubated at 37° C. for 4 to 24 hours. The cells are then spun down and the supernatant containing the digest of surface exposed proteins is analyzed by mass spectroscopy (vide infra). At the end of the procedure, cell integrity is observed by Scanning Electron Microscopy (SEM). Cells, so treated, have a strikingly different morphology, as seen under the SEM, which is best described as a “clean shave”. That is, the normal spongy or furry appearance is replaced by a smooth spherical morphology. Maintaining cell integrity throughout this operation is important. The intact cell membrane protects all intracellular proteins from the proteolytic step required for identification. Any ruptured cells therefore spill intracellular proteins into the extracellular environment where they are digested and erroneously identified as surface exposed proteins.

In the second strategy, proteins with a natural tropism for membranes are copurified with membranes by simple centrifugation. In principle, this separates proteins into two classes; soluble and membrane bound. In this case, the class of interest is membrane bound because many of these are also surface exposed as well. Experimentally, cells are ruptured in the absence of detergent by sonication or shear and the lysate is subjected to differential centrifugation. The pellet from a high speed spin (20,000×g) consists of membranes and their associated proteins. This pellet is then dissolved in SDS load buffer and then separated by SDS PAGE. The gel, after staining, shows a large number of still intact proteins that share the quality of being membrane bound. The protein bands from this gel are then cut and exposed to trypsin for the obligate digestion before mass spectroscopic identification.

It should be pointed out that many of these proteins are actually on the inside (cytoplasmic) surface of the membrane and may well have no surface exposure at all. There are several advantages to this method, however, that offset this apparent lack of selectivity. Many proteins are not apprehended by the aforementioned technique of surface digestion are, however, captured by membrane enrichment. Surface digestion fails for proteins that are minimally exposed to the protease. This would be the case for proteins that are highly structured, membrane buried, or heavily glycosylated. In the final analysis both techniques have different merits and shortcomings and can be used in a complementary way.

In a typical example, a membrane preparation was dissolved in SDS load buffer and the proteins separated by SDS PAGE. After staining with colloidal Coomassie Blue stain, fifteen gel bands containing the entire sample lane were excised and the bands digested individually with trypsin. The tryptic peptides were analyzed using microcapillary reversed-phase liquid chromatography—nano-electrospray tandem mass spectrometry (LC-MS/MS) on a Finnigan LCQ Deca quadrupole ion trap mass spectrometer. Acquisition was performed using a “3 CADs experiment”. Using SEQUEST software, the uninterpreted tandem mass spectrometric information was used to search appropriate sequence databases to identify the proteins present in each gel band.

Example 7 Protein Identification

In order to identify the polypeptide components in the complex surface digest mixture, an analytical technique is used to separate and sequence multiple peptides with high sensitivity over a large concentration range. Tandem mass spectrometry (MS/MS) has been shown to be a powerful approach to analyze proteins from both gels and in solution. MS/MS first uses a mass analyzer to separate a peptide ion from a mixture of ions, then uses a second step or mass analyzer to activate and dissociate the ion of interest. This process, known as collision induced dissociation (CID) causes the peptide to fragment at the peptide bonds between the amino acids, and therefore, the fragmentation pattern of a peptide can be used to determine its amino acid sequence. In addition, the SEQUEST computer algorithm can be used to search the experimental fragmentation spectrum directly against protein or translated nucleic acid sequence databases. For peptides above roughly 800-900 Da in size, a single spectrum can uniquely identify a protein.

To sequence multiple peptides from a complex mixture, a reversed phase chromatography system is coupled to an electrospray ion trap mass spectrometer. In this system, it is known that high sensitivity (down to sub-femtomole levels) is attained by minimizing both flow rate and column diameter to concentrate the elution volume and direct as much of the column effluent as possible into the orifice of the mass spectrometer detector. Initial experiments separated peptides using a reversed phase gradient of 1% acetonitrile/minute. In order to increase chromatographic separation, longer gradients, down to 0.28% acetonitrile/minute, and slower flow rates (50 nL/min) will be employed. To maximize the coverage of proteins present in the sample, the data-dependent acquisition feature of the ion trap is employed. The instrument is programmed to acquire a single ms scan in the range of m/z 375-600, then to obtain ms/ms data on the top two ions in that range. It then acquires another ms scan in the range of m/z 600-1000, and obtains ms/ms data on the top two ions in that range. This results in better coverage of the larger peptides.

Dynamic exclusion is used to prevent reacquisition of tandem mass spectra of ions once a spectrum had been acquired for a particular m/z value. The isotopic exclusion function excludes the ion associated with the ¹³C isotope of peptides from the list of ions slated for MS/MS. A 3-μ mass width window is selected for this purpose. Using these data-dependent features dramatically increases the number of peptide ions that will be selected for CID analysis.

Example 8 Sequest Analysis

The LC-MS/MS data acquisition conditions described above typically results in fragmentation data for more than 2000 peptide ions for each run. Using the Sequest algorithm, this data is searched against a composite protein sequence database containing the translated ORFs from Alloiococcus otitidis combined with the non-redundant protein sequence database OWL. Sequest search conditions using a modified trypsin selectivity allows a differential search of +16 Da on methionine (to account for met oxidation). Candidate matches identified by Sequest are confirmed using the following manual procedure. Those matches with Xcorr values greater than 2.5 (a measure of the similarity of the experimental ms/ms data to that generated from the sequence database), and delCn values greater than 0.1 (delCn measures the normalized difference between the Xcorr values of the first and second matches), are chosen for further analysis. The fragmentation spectra from good matches are checked for reasonable signal/noise, and the list of matched ions are examined for reasonable continuity. Some matches that are not acceptable alone are only included if other confirmatory ms/ms data is generated by the same sample.

Example 9 Cloning and Protein Expression

Primer sets are designed for PCR amplification of desired ORFs such that the forward 5′ primer anneals at the start of the predicted mature protein. For lipoproteins, the 5′ forward primer is designed to anneal just after the codon encoding a cysteine residue of the mature protein to minimize disulfide bridging. Design of the opposing reverse 3′ primers independent upon the type of predicted protein. For those proteins that contain an LPXTG, the primer is designed such that it anneals at the beginning (5′ end) of the cell wall anchor region. For all other predicted proteins, primers are redesigned such that they anneal at the 3′ end of the ORF. Additionally, the 5′-forward primer is initially designed to allow an in-frame fusion to thioredoxin with the opposing 3′-reverse primer allowing read-through to include a downstream his-patch and V5 epitope (pBAD/thio-TOPO®, Invitrogen, Carlsbad, Calif.). In parallel, these same PCR products are cloned into pCR®T7TOPO® (Invitrogen, Carlsbad, Calif.). This allows for an N-terminal fusion to a Xpress epitope and a his-tag for purification.

All PCR reactions are performed using Alloiococcus otitidis chromosomal DNA as the template. PCR products are transformed into the E. coli host, TOP10, and plated on SOB containing 100 μg/mL ampicillin. Colonies are screened by PCR amplification using a vector specific 5′ primer and the specific 3′ reverse primer annealing to the gene insert. Colonies are seeded into wells of 96 well microtiter plates containing 50 μL 50% glycerol. Ten-12 colonies per gene are seeded in one row of the plate. In a second 96 well PCR plate, 50 μL reactions are set up specific to the gene of interest. One μL of the cells suspended in glycerol is used as template in the PCR reaction. Reactions that produce bands of the expected size are analyzed further. The cells that are seeded in 50% glycerol have SOB media added to them and incubated at 37° C. for 5-8 hours and frozen at −70° C.

PCR positive colonies are inoculated into 2 mL cultures for overnight growth. Part of the culture is used to prepare plasmid DNA that is then analyzed by restriction digestion to confirm the inserts while another part is used to seed 10 mL expression cultures (for pBAD plasmids) for expression. Mid-log phase cultures are induced with 0.5% L-arabinose for 2-3 hours. T7/NT plasmids are transformed into the expression strain BLR(DE3) pLysS before screening. T7/NT cultures are induced by the addition of 1 mM IPTG and incubated for 2 hours. Whole cell lysates of induced cultures are run on SDS-PAGE in duplicate. One gel is stained with Coomassie and the other transferred to nitrocellulose and probed with antibody to the relevant epitope tag.

Positive clones are grown in 1-2 L volumes and induced for large-scale purification. Solubility and expression level of the recombinant proteins are assessed by freeze-thaw lysis of the cells, followed by DNase/RNase digestion and centrifugation at 9,000×g for 15 minutes in a RC5B refrigerated centrifuge. The soluble fraction is removed from the insoluble material and both are then separated and evaluated for protein localization and expression by SDS-PAGE. Soluble fusion proteins are purified by passing the soluble fraction of lysed cells over Ni-NTA (Qiagen) resin and eluting the bound proteins with imidazole. Eluted proteins are buffer exchanged on PD-10 columns (Amersham Pharmacia Biotech, Piscataway, N.J.).

Insoluble recombinant proteins are washed using centrifugation 3 times in PBS, 0.1% Triton-X100. The inclusion bodies are then solubilized in PBS-4 M urea and buffer exchanged through a PD-10 column (Amersham Pharmacia) into PBS, 0.01% Triton-X100, 0.5 M NaCl. Proteins are quantitated by the Lowry assay (Lowry et al., 1951), and checked for purity and concentration by SDS-PAGE.

Example 10 Generation of Polyclonal Antisera and Monoclonal Antibodies

To generate monoclonal antibodies, female, eight week old Blab/c mice are inoculated intraperitoneally with the gene products three times in a four week period (week 0, 2, 4). The dosage of the protein gene product is between 5 and 50 go. Two different fusion procedures are performed. The first fusion is done after a three-month rest period and an intraperitoneal boost with the protein; the second fusion is done after a four-month rest period and a boost by the same route. During the immunization and rest period, mouse sera recollected and tested for antibody activity by ELISA using the protein as the coating antigen.

For both fusions, the spleens are excised from two immunized mice about 72 hours after the last injection and mixed with the nonsecreting X63Ag8.653 mouse (Balb/c) myeloma cells in a 5:1 ratio (splenocytes:myeloma). The cells are allowed to fuse for four minutes in 50% (wt/wt) polyethylene glycol 1500 and 10% dimethyl sulfoxide in Dulbecco's Modified Eagle medium (D-MEM). Multiple dilutions of the fused cells are then made into the selection medium, i.e., D-MEM supplemented with hypoxanthine, aminopterin, thymine, 10% fetal bovine serum, and 10% NCTC-109 medium supplement (Gibco-BRL). The reactivity in each dilution is evaluated by SDS-PAGE western blots, dot blots, and ELISA using the gene product protein and whole bacterial cells as. the, detection antigens. The positive reacting hybridomas are identified and saved. These hybridomas are then further subcloned by the limiting dilution procedure to isolate the individual antibody secreting cells. The selected hybridoma cells are then used to prepare the monoclonal antibodies. This is either performed by growing them in D-MEM and concentrating the supernatant by ammonium sulfate precipitation, or by injecting mice with the hybridoma cells and collecting the resulting ascites fluid.

Example 11 Elisa Titration of Mouse and Human Sera, Monoclonal Antibodies, and Mucosal Washings Against Gene Products and Whole Bacteria

The levels of antibodies elicited by the gene products cloned and expressed as per Example 10 toward themselves and whole bacterial cells are measured by Enzyme linked immunosorbent assay (ELISA). For the whole cell ELISA, the bacteria are grown overnight on agar medium and swabbed into PBS. The turbidity of the cells is adjusted to 0.10 at 600 nm and 100 μl added to the wells of a 96 ELISA plate. The cells are dried overnight at 37° C., sealed with a mylar plate sealer and stored at 4° C. until needed. On the day of the assay, the residual protein binding sites are blocked by adding 5% non-fat dry milk in PBS with 0.1% Tween 20 (BLOTTO) and incubating at 37° C. for one hour. The blocking solution is then removed and 100 μl of sera serially diluted in the wells with BLOTTO. The sera are allowed to incubate for 1 h at 37° C. The plate wells are soaked with 300 ml PBS containing 0.1% Tween 20 for 30 seconds and washed 3 times for 5 seconds with a SkanWasher 300 plate washer (Skatron Instruments AS, Norway) and then incubated 1 hr at 37° C. with goat anti-mouse IgG conjugated to alkaline phosphatase (BioSource International) diluted 1:1000 in BLOTTO. After washing, the plates are developed at room temperature with 100 μl per well of 1 mg/ml p-nitrophenyl phosphate dissolved in diethanolamine buffer. Development is stopped by adding 50 μl of 3N NaOH to each well. The absorbance of each well is read at 405 nm and titers calculated by linear regression. The titer is reported as the inverse of the dilution extrapolated to an absorption value of 0.10 units.

For the antigen specific ELISA's, the proteins are diluted to a concentration of 5 μg/ml in a 50 mM sodium carbonate buffer (pH 9.8) containing 0.02% sodium azide (Sigma Chemical Co.). One hundred micro liters is added to each well of a 96 well E.I.A./R.I.A medium binding ELISA plate (Costar Corp., Cambridge, Mass.) and incubated for 16 hours at 4° C. The plates are washed and subsequently treated the same as described for whole cell ELISA procedure except, in addition to dilutions of sera, mucosal washings and monoclonal antibody suspensions are tested as well.

Example 12 Immunogold Labeling of Alloiococcus Otitidis and low voltage Scanning Electron Microscopy

Surface exposure of proteins on Alloiococcus otitidis is assessed by immunogold labeling of whole bacteria and electron microscopy. Bacteria cells are labeled as previously described (Olmsted et al., 1993). Briefly, late-log phase bacterial cultures are washed twice, and resuspended to a concentration of 1×10⁸ cells/ml in 10 mM phosphate buffered saline (PBS) (pH 7.4) and placed on poly-L-lysine coated glass coverslips. Excess bacteria are gently washed from the coverslips and unlabeled samples are placed into fixative (2.0% glutaraldehyde, in a 0.1 M sodium cacodylate buffer containing 7.5% sucrose) for 30 min. Bacteria to be labeled with colloidal gold are washed with PBS containing 0.5% bovine serum albumin, and the pre-immune or hyper-immune mouse polyclonal antibody prepared above applied for 1 hour at room temperature. Bacteria are then gently washed, and a 1:6 dilution of goat anti-mouse conjugated to 18 nm colloidal gold particles (Jackson ImmunoResearch Laboratories, Inc., West Grove, Pa.) applied for 10 min at room temperature. Finally, all samples are washed gently with PBS, and placed into the fixative described above. The fixative is washed from samples twice for 10 min in 0.1 M sodium cacodylate buffer, and posffixed for 30 min in 0.1 M sodium cacodylate containing 1% osmium tetroxide. The samples are then washed twice with 0.1 M sodium cacodylate, dehydrated with successive concentrations of ethanol, critical point dried by the CO₂ method of Anderson (Anderson, 1951) using a Samdri-780A (Tousimis, Rockville, Md.), and coated with a 1-2 nm discontinuous layer of platinum. Alloiococcus otitidis cells are then viewed with a LEO 1550 field emission scanning electron microscope operated at low accelerating voltages (1-4.5 keV) using a secondary electron detector for conventional topographical imaging and a high-resolution Robinson backscatter detector to enhance the visualization of colloidal gold by atomic number contrast.

Example 13 Intranasal and Parenteral Immunization of Mice

Six-week old, pathogen-free mice are purchased from Jackson Laboratories (Bar Harbor, Maine) and housed in cages under standard temperature, humidity, and lighting conditions. The mice, at 10 animals per group, are immunized with an appropriate amount of the protein(s) to be tested. For parenteral immunization, the protein is mixed with 100 μg of monophosphoryl lipid A (MPL™) (Corixa, Hamilton, Mont.) per dose to a final volume of 200 μl in saline and then injected subcutaneously (SC) into mice. All groups receive a booster with the same dose and by the same route 3 and 5 weeks after the primary immunization. Control mice are injected with MPL™ alone. All mice are bled two weeks after the last boosting; sera is then isolated and stored at −20° C. For intranasal (IN) immunization, mice receive three IN immunizations one week apart. On each occasion, an appropriate dose of the protein to be tested is formulated with 0.1 μg of CT-E29H, a genetically modified cholera toxin that is reduced in enzymatic activity and toxicity (Tebbey et al., 2000), and slowly instilled into the nostril of each mouse in a 10 μl volume. Mice immunized with CT-E29H alone are used as controls. Serum samples are collected one week after the last immunization.

Example 14 In vitro Opsonphagocytosis Analysis

An in vitro opsonic reaction, that may mimic the in vivo reaction, is achieved when a mixture of Alloiococcus otitidis cells, heat inactivated human serum containing specific antibodies to the alloiococcal strain, and an exogenous complement source are incubated together. Opsonophagocytosis proceeds during incubation of freshly isolated human polymorphonuclear cells (PMN's) and the antibody/complement/alloiococcal cell mixture. Bacterial cells that are coated with antibody and complement are killed upon opsonophagocytosis. Colony forming units (cfu) of surviving bacteria that escape from opsonophagocytosis are determined by plating the assay mixture. Titers are reported as the reciprocal of the highest dilution that gives ≧50% bacterial killing, as determined by comparison to assay controls. Specimens, which demonstrate less than 50% killing at the lowest serum dilution tested (1:8) are reported as having an OPA titer of 4. The highest dilution tested is 1:2560. Samples with ≧50% killing at the highest dilution are repeated, beginning with a higher initial dilution.

The method described herein is a modification of Gray's method (Gray, B. M. 1990). The assay mixture is assembled in a 96-well microtiter tissue culture plate at room temperature. The assay mixture consists of 10 μL of test serum (a series of two-fold dilutions) heated to 56° C. for 30 minutes prior to testing, 10 μL of preclostral bovine serum (complement source) having no opsonic activity for the bacterial test strain, and 20 μL of buffer containing viable Alloiococcus otitidis organisms. This mixture is incubated at 37° C. without CO₂ for 30 minutes with shaking. Next, 40 μL of human PMNs, freshly prepared from heparinized peripheral blood by dextran sedimentation and Percoll density centrifugation, suspended in buffer at a concentration of 1×10⁶/mL is added. The assay plate(s) is then incubated at 37° C. for an additional 90 minutes with vigorous shaking. Aliquots from each well are dispensed onto the upper ¼ of a 15×100 mm blood agar plate. The blood agar plate is tilted while pipetting to allow the liquid suspension to “run” down the plate. Plates are incubated overnight in 5% CO₂ at 37° C. The viable cfu are counted the following morning. Negative control wells, lacking bacterial cells, test serum, complement and/or phagocytes in appropriate combination are included in each assay. A test serum control, which contains test serum plus bacterial cells and heat-inactivated complement, is included for each individual serum. This control is used to assess whether the presence of antibiotics or other serum components are capable of killing the bacterial strain directly (Le. in the absence of complement or PMN's). A human serum with known opsonic titer is used as a positive human serum control. The opsonic antibody titer for each unknown serum is calculated as the reciprocal of the initial dilution of serum giving 50% cfu reduction compared to the control without serum.

Example 15 Mouse Nasal Clearance Model

The gene products are evaluated in a mouse nasal clearance model. Groups of at least ten mice, of either the C3H/heJ or Balb/C strains, are immunized as described above. Approximately two weeks after the last immunization, the mice are anesthetized with 1.2 mg of ketamine HCl (Ft. Dodge Laboratories, Ft. Dodge, Iowa) by i.p. injection. The mice are then challenged intranasally by placing 10 μL of a suspension the 1104-92 isolate of Alloiococcus otitidis prepared to an A₅₅₀ of 0.5 in the nose and allowing the animal to inhale it. The 1104-92 isolate used for this challenge is passaged twice in mice by intranasal instillation to select for a variant with optimal colonization capacity. After five hours the mice are killed, their nasal turbinates removed, homogenized in 2 ml of sterile saline, appropriately diluted, and plated onto selective agar medium. The selective medium is a Columbia based agar supplemented with 0.5% Tween-80, 0.5% azide and 20 mg/L erythromycin. Owing to its slow growth, Alloiococcus otitidis requires 3 to 4 days before colonies a visible on this medium. The degree of clearance of the immunized mice is calculated as the percent decrease in colony forming units (CFUs) and statistically compared to a set of mice immunized with an unrelated protein such as CRM, Keyhole Limpet Hemocyanin (KLH) or other protein not derived from Alloiococcus otitidis.

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1. An isolated polynucleotide of an Alloiococcus otitidis genomic sequence, wherein the polynucleotide comprises a nucleotide sequence having at least about 70% identity to a nucleotide sequence chosen from one of odd numbered sequences from SEQ ID NO: 1 to SEQ ID NO: 6649, a complement thereof, a degenerate variant thereof, and a fragment thereof.
 2. The polynucleotide of claim 1, wherein the polynucleotide is a complement to a nucleotide sequence chosen from one of odd numbered sequences from SEQ ID NO: 1 to SEQ ID NO: 6649, a complement thereof, a degenerate variant thereof, and a fragment thereof.
 3. The polynucleotide of claim 2, wherein the polynucleotide is selected from the group consisting of genomic DNA, cDNA and RNA.
 4. The polynucleotide of claim 3, wherein the polynucleotide further comprises heterologous nucleotides.
 5. An isolated polynucleotide which hybridizes to a nucleotide sequence chosen from one of the odd numbered sequences from SEQ ID NO: 1 to SEQ ID NO: 6649, a complement thereof, a degenerate variant thereof, or a fragment thereof, under high stringency hybridization conditions.
 6. The polynucleotide of claim 5, wherein the polynucleotide hybridizes under intermediate stringency hybridization conditions.
 7. An isolated polynucleotide of an Alloiococcus otitidis genomic sequence, wherein the polynucleotide comprises a nucleotide sequence chosen from one of odd numbered sequences from SEQ ID NO: 1 to SEQ ID NO: 6649, a complement thereof, a fragment thereof, or a degenerate variant thereof, and encodes a polypeptide, a biological equivalent thereof, or a fragment thereof, and is selected from the group consisting of: (a) an Alloiococcus otitidis polypeptide predicted by SignalP algorithm analysis as having met all four criteria set out in the SignalP algorithm for a polypeptide having a signal peptide and predicted by HMM SignalP algorithm analysis as having a signal peptide; (b) an Alloiococcus otitidis polypeptide predicted by SignalP algorithm analysis as having met three of the four criteria set out in the SignalP algorithm for a polypeptide having a signal peptide and predicted by HMM SignalP algorithm analysis as having a signal peptide; (c) an Alloiococcus otitidis polypeptide predicted by HMM Signal P algorithm analysis as having a signal peptide; (d) an Alloiococcus otitidis polypeptide predicted by HMM Signal P algorithm analysis as being a non-secretory protein and by PSORT program to be localized to the cytoplasmic membrane; (e) an Alloiococcus otitidis polypeptide identified by BlastP analysis; (f) an Alloiococcus otitidis polypeptide identified by Pfam analysis; (g) an Alloiococcus otitidis polypeptide identified using proteomics methodology as sharing homology with surface exposed proteins of Streptococcus pneumoniae; (h) an Alloiococcus otitidis lipoprotein; (i) an Alloiococcus otitidis polypeptide having a LPXTG motif, wherein the polypeptide is covalently attached to the peptidoglycan layer; (j) an Alloiococcus otitidis polypeptide, wherein the polypeptide is non-covalently associated with the peptidoglycan layer; (k) an Alloiococcus otitidis polypeptide having an RGDX motif wherein X is not a proline residue; (l) an Alloiococcus otitidis polypeptide predicted by BlastP as being involved in capsule biosynthesis and transport; (m) an Alloiococcus otitidis polypeptide identified by BlastP as being localized within the capsule loci of the Alloiococcus otitidis genome; (n) an Alloiococcus otitidis polypeptide predicted by BlastP as being associated with sporulation; (o) an Alloiococcus otitidis polypeptide encoded by unique ORFs identified by BlastP analysis as having a BlastP ‘E Value’ of >e⁻¹⁰; (p) an Alloiococcus otitidis polypeptide identified by Glimmer™ ORF finder program; (q) an Alloiococcus otitidis polypeptide identified by GeneMark™ ORF finder program; (r) an Alloiococcus otitidis polypeptide identified by an ORF finder program that searches for an ATG, GTG or TTG Start codon between a Stop-Stop region; and (s) an Alloiococcus otitidis polypeptide identified by an ORF finder program that searches for a transmembrane domain between two Stop codons and a Start codon immediately upstream of this transmembrane region.
 8. The polynucleotide of claim 7, wherein the polynucleotide is a complement to a nucleotide sequence selected from one of the odd numbered sequences from SEQ ID NO: 1 to SEQ ID NO: 6649, a degenerate variant thereof, and a fragment thereof.
 9. The polynucleotide of claim 8, wherein the polynucleotide is selected from the group consisting of genomic DNA, cDNA and RNA.
 10. The polynucleotide of claim 9, wherein the polynucleotide further comprises heterologous nucleotides.
 11. The polynucleotide of claim 10, wherein the polynucleotide encodes a fusion polypeptide.
 12. The polynucleotide of claim 7 wherein the polynucleotide encodes a polypeptide, which is predicted by SignalP algorithm analysis as having met all four criteria set out in the SignalP algorithm for a polypeptide having a signal peptide, and which is predicted by HMM SignalP algorithm analysis as having a signal peptide, and the polynucleotide is selected from one of Seq. ID No. 89, Seq. ID No. 127, Seq. ID No. 131, Seq. ID No. 133, Seq. ID No. 161, Seq. ID No. 163, Seq. ID No. 213, Seq. ID No. 215, Seq. ID No. 225, Seq. ID No. 249, Seq. ID No. 251, Seq. ID No. 287, Seq. ID No. 289, Seq. ID No. 369, Seq. ID No. 371, Seq. ID No. 375, Seq. ID No. 377, Seq. ID No. 497, Seq. ID No. 503, Seq. ID No. 505, Seq. ID No. 527, Seq. ID No. 549, Seq. ID No. 575, Seq. ID No. 617, Seq. ID No. 657, Seq. ID No. 659, Seq. ID No. 661, Seq. ID No. 675, Seq. ID No. 715, Seq. ID No. 717, Seq. ID No. 745, Seq. ID No. 747, Seq. ID No. 755, Seq. ID No. 757, Seq. ID No. 759, Seq. ID No. 761, Seq. ID No. 773, Seq. ID No. 807, Seq. ID No. 967, Seq. ID No. 973, Seq. ID No. 975, Seq. ID No. 1013, Seq. ID No. 1025, Seq. ID No. 1027, Seq. ID No. 1039, Seq. ID No. 1075, Seq. ID No. 1089, Seq. ID No. 1195, Seq. ID No. 1197, Seq. ID No. 1207, Seq. ID No. 1239, Seq. ID No. 1243, Seq. ID No. 1245, Seq. ID No. 1269, Seq. ID No. 1315, Seq. ID No. 1317, Seq. ID No. 1331, Seq. ID No. 1365, Seq. ID No. 1367, Seq. ID No. 1369, Seq. ID No. 1445, Seq. ID No. 1447, Seq. ID No. 1513, Seq. ID No. 1517, Seq. ID No. 1545, Seq. ID No. 1549, Seq. ID No. 1561, Seq. ID No. 1569, Seq. ID No. 1571, Seq. ID No. 1585, Seq. ID No. 1643, Seq. ID No. 1653, Seq. ID No. 1661, Seq. ID No. 1663, Seq. ID No. 1707, Seq. ID No. 1733, Seq. ID No. 1737, Seq. ID No. 1755, Seq. ID No. 1765, Seq. ID No. 1767, Seq. ID No. 1775, Seq. ID No. 1791, Seq. ID No. 1805, Seq. ID No. 1875, Seq. ID No. 1969, Seq. ID No. 1981, Seq. ID No. 2053, Seq. ID No. 2055, Seq. ID No. 2087, Seq. ID No. 2089, Seq. ID No. 2091, Seq. ID No. 2105, Seq. ID No. 2115, Seq. ID No. 2149, Seq. ID No. 2151, Seq. ID No. 2159, Seq. ID No. 2177, Seq. ID No. 2277, Seq. ID No. 2293, Seq. ID No. 2321, Seq. ID No. 2347, Seq. ID No. 2351, Seq. ID No. 2353, Seq. ID No. 2365, Seq. ID No. 2395, Seq. ID No. 2421, Seq. ID No. 2425, Seq. ID No. 2427, Seq. ID No. 2429, Seq. ID No. 2449, Seq. ID No. 2459, Seq. ID No. 2525, Seq. ID No. 2531, Seq. ID No. 2607, Seq. ID No. 2651, Seq. ID No. 2679, Seq. ID No. 2693, Seq. ID No. 2699, Seq. ID No. 2703, Seq. ID No. 2753, Seq. ID No. 2785, Seq. ID No. 2813, Seq. ID No. 2829, Seq. ID No. 2835, Seq. ID No 2841, Seq. ID No. 2879, Seq. ID No. 2881, Seq. ID No. 2935, Seq. ID No. 2937, Seq. ID No. 2949, Seq. ID No. 2965, Seq. ID No. 2967, Seq. ID No. 2973, Seq. ID No. 3007, Seq. ID No. 3009, Seq. ID No. 3011, Seq. ID No. 3029, Seq. ID No. 3031, Seq. ID No. 3109, Seq. ID No. 3111, Seq. ID No. 3219, Seq. ID No. 3223, Seq. ID No. 3273, Seq. ID No. 3297, Seq. ID No. 3331, Seq. ID No. 3335, Seq. ID No. 3341, Seq. ID No. 3349, Seq. ID No. 3353, Seq. ID No. 3355, Seq. ID No. 3377, Seq. ID No. 3391, Seq. ID No. 3425, Seq. ID No. 3449, Seq. ID No. 3493, Seq. ID No. 3573, Seq. ID No. 3611, Seq. ID No. 3619, Seq. ID No. 3689, Seq. ID No. 3753, Seq. ID No. 3755, Seq. ID No. 3765, Seq. ID No. 3781, Seq. ID No. 3783, Seq. ID No. 3851, Seq. ID No. 3903, Seq. ID No. 4005, Seq. ID No. 4007, Seq. ID No. 4027, Seq. ID No. 4073, Seq. ID No. 4137, Seq. ID No. 4141, Seq. ID No. 4143, Seq. ID No. 4145, Seq. ID No. 4225, Seq. ID No. 4343, Seq. ID No. 4385, Seq. ID No. 4399, Seq. ID No. 4469, Seq. ID No. 4483, Seq. ID No 4493, Seq. ID No. 4495, Seq. ID No. 4533, Seq. ID No. 4699, Seq. ID No. 4709, Seq. ID No. 4711, Seq. ID No. 4735, Seq. ID No. 4827, Seq. ID No. 4871, Seq. ID No. 4873, Seq. ID No. 4879, Seq. ID No. 4921, Seq. ID No. 4981, Seq. ID No. 5115, Seq. ID No. 5267, Seq. ID No. 5341, Seq. ID No. 5387, Seq. ID No. 5465, Seq. ID No. 5467, Seq. ID No. 5479, Seq. ID No. 5497, Seq. ID No. 5513, Seq. ID No. 5543, Seq. ID No. 5545, Seq. ID No. 5567, Seq. ID No. 5587, Seq. ID No. 5589, Seq. ID No. 5591, Seq. ID No. 5611, Seq. ID No. 5621, Seq. ID No. 5641, Seq. ID No. 5681, Seq. ID No. 5719, Seq. ID No. 5771, Seq. ID No. 5783, Seq. ID No. 5895, Seq. ID No. 5899, Seq. ID No. 5901, Seq. ID No. 5927, Seq. ID No. 5929, Seq. ID No. 5939, Seq. ID No. 5987, Seq. ID No. 6013, Seq. ID No. 6087, Seq. ID No. 6089, Seq. ID No. 6091, Seq. ID No. 6093, Seq. ID No. 6095, Seq. ID No. 6103, Seq. ID No. 6169, Seq. ID No. 6185, Seq. ID No. 6187, Seq. ID No. 6195, Seq. ID No. 6197, Seq. ID No. 6203, Seq. ID No. 6205, Seq. ID No. 6221, Seq. ID No. 6223, Seq. ID No. 6229, Seq. ID No. 6291, Seq. ID No. 6415, Seq. ID No. 6417, Seq. ID No. 6473, Seq. ID No. 6507, Seq. ID No. 6543, Seq. ID No. 6595, Seq. ID No. 6597, Seq. ID No. 6599, Seq. ID No. 6601 and Seq. ID No.
 6603. 13. The polynucleotide of claim 7 wherein the polynucleotide encodes a polypeptide, which is predicted by SignalP algorithm analysis as having met three of the four criteria set out in the SignalP algorithm for a polypeptide having a signal peptide and which is predicted by HMM SignalP algorithm analysis as having a signal peptide, and the polynucleotide is selected from one of Seq. ID No. 7, Seq. ID No. 11, Seq. ID No. 23, Seq. ID No. 45, Seq. ID No. 47, Seq. ID No. 53, Seq. ID No. 59, Seq. ID No. 65, Seq. ID No. 67, Seq. ID No. 87, Seq. ID No. 91, Seq. ID No. 139, Seq. ID No. 151, Seq. ID No. 159, Seq. ID No. 165, Seq. ID No. 169, Seq. ID No. 185, Seq. ID No. 211, Seq. ID No. 217, Seq. ID No. 235, Seq. ID No. 237, Seq. ID No. 239, Seq. ID No. 271, Seq. ID No. 285, Seq. ID No. 291, Seq. ID No. 327, Seq. ID No. 349, Seq. ID No. 385, Seq. ID No. 387, Seq. ID No. 407, Seq. ID No. 427, Seq. ID No. 431, Seq. ID No. 455, Seq. ID No. 457, Seq. ID No. 495, Seq. ID No. 499, Seq. ID No. 511, Seq. ID No. 513, Seq. ID No. 515, Seq. ID No. 525, Seq. ID No. 545, Seq. ID No. 547, Seq. ID No. 557, Seq. ID No. 569, Seq. ID No. 589, Seq. ID No. 591, Seq. ID No. 593, Seq. ID No. 595, Seq. ID No. 609, Seq. ID No. 637, Seq. ID No. 639, Seq. ID No. 641, Seq. ID No. 653, Seq. ID No. 669, Seq. ID No. 679, Seq. ID No. 719, Seq. ID No. 723, Seq. ID No. 739, Seq. ID No. 749, Seq. ID No. 751, Seq. ID No. 763, Seq. ID No. 765, Seq. ID No. 769, Seq. ID No. 777, Seq. ID No. 779, Seq. ID No. 781, Seq. ID No. 819, Seq. ID No. 895, Seq. ID No. 903, Seq. ID No. 905, Seq. ID No. 909, Seq. ID No. 935, Seq. ID No. 937, Seq. ID No. 951, Seq. ID No. 955, Seq. ID No. 979, Seq. ID No. 981, Seq. ID No. 983, Seq. ID No. 985, Seq. ID No. 1005, Seq. ID No. 1007, Seq. ID No. 1009, Seq. ID No. 1015, Seq. ID No. 1019, Seq. ID No. 1029, Seq. ID No. 1031, Seq. ID No. 1047, Seq. ID No. 1091, Seq. ID No. 1111, Seq. ID No. 1137, Seq. ID No. 1151, Seq. ID No. 1153, Seq. ID No. 1169, Seq. ID No. 1173, Seq. ID No. 1183, Seq. ID No. 1191, Seq. ID No. 1193, Seq. ID No. 1213, Seq. ID No. 1223, Seq. ID No. 1229, Seq. ID No. 1247, Seq. ID No. 1259, Seq. ID No. 1283, Seq. ID No. 1307, Seq. ID No. 1319, Seq. ID No. 1321, Seq. ID No. 1327, Seq. ID No. 1341, Seq. ID No. 1343, Seq. ID No. 1347, Seq. ID No. 1389, Seq. ID No. 1401, Seq. ID No. 1429, Seq. ID No. 1479, Seq. ID No. 1551, Seq. ID No. 1559, Seq. ID No. 1579, Seq. ID No. 1587, Seq. ID No. 1621, Seq. ID No. 1627, Seq. ID No. 1633, Seq. ID No. 1645, Seq. ID No. 1647, Seq. ID No. 1649, Seq. ID No. 1655, Seq. ID No. 1665, Seq. ID No. 1667, Seq. ID No. 1671, Seq. ID No. 1677, Seq. ID No. 1679, Seq. ID No. 1681, Seq. ID No. 1695, Seq. ID No. 1703, Seq. ID No. 1705, Seq. ID No. 1731, Seq. ID No. 1753, Seq. ID No. 1759, Seq. ID No. 1763, Seq. ID No. 1787, Seq. ID No. 1797, Seq. ID No. 1821, Seq. ID No. 1823, Seq. ID No. 1833, Seq. ID No. 1839, Seq. ID No. 1841, Seq. ID No. 1843, Seq. ID No. 1893, Seq. ID No. 1917, Seq. ID No. 1919, Seq. ID No. 1971, Seq. ID No. 1991, Seq. ID No. 2013, Seq. ID No. 2015, Seq. ID No. 2017, Seq. ID No. 2019, Seq. ID No. 2033, Seq. ID No. 2035, Seq. ID No. 2049, Seq. ID No. 2081, Seq. ID No. 2083, Seq. ID No. 2085, Seq. ID No. 2111, Seq. ID No. 2113, Seq. ID No. 2123, Seq. ID No. 2125, Seq. ID No. 2127, Seq. ID No. 2131, Seq. ID No. 2133, Seq. ID No. 2153, Seq. ID No. 2161, Seq. ID No. 2171, Seq. ID No. 2175, Seq. ID No. 2179, Seq. ID No. 2187, Seq. ID No. 2201, Seq. ID No. 2203, Seq. ID No. 2221, Seq. ID No. 2237, Seq. ID No. 2249, Seq. ID No. 2251, Seq. ID No. 2255, Seq. ID No. 2261, Seq. ID No. 2263, Seq. ID No. 2271, Seq. ID No. 2279, Seq. ID No. 2283, Seq. ID No. 2285, Seq. ID No. 2289, Seq. ID No. 2295, Seq. ID No. 2305, Seq. ID No. 2307, Seq. ID No. 2317, Seq. ID No. 2319, Seq. ID No. 2323, Seq. ID No. 2325, Seq. ID No. 2343, Seq. ID No. 2349, Seq. ID No. 2385, Seq. ID No. 2393, Seq. ID No. 2423, Seq. ID No. 2453, Seq. ID No. 2491, Seq. ID No. 2497, Seq. ID No. 2499, Seq. ID No. 2507, Seq. ID No. 2515, Seq. ID No. 2517, Seq. ID No. 2521, Seq. ID No. 2523, Seq. ID No. 2527, Seq. ID No. 2533, Seq. ID No. 2535, Seq. ID No. 2541, Seq. ID No. 2543, Seq. ID No. 2547, Seq. ID No. 2549, Seq. ID No. 2557, Seq. ID No. 2573, Seq. ID No. 2583, Seq. ID No. 2601, Seq. ID No. 2603, Seq. ID No. 2621, Seq. ID No. 2653, Seq. ID No. 2681, Seq. ID No. 2691, Seq. ID No. 2701, Seq. ID No. 2733, Seq. ID No. 2739, Seq. ID No. 2801, Seq. ID No. 2807, Seq. ID No. 2815, Seq. ID No. 2819, Seq. ID No. 2821, Seq. ID No. 2823, Seq. ID No. 2833, Seq. ID No. 2837, Seq. ID No. 2839, Seq. ID No. 2845, Seq. ID No. 2853, Seq. ID No. 2861, Seq. ID No. 2865, Seq. ID No. 2873, Seq. ID No. 2875, Seq. ID No. 2877, Seq. ID No. 2883, Seq. ID No. 2895, Seq. ID No. 2905, Seq. ID No. 2939, Seq. ID No. 2941, Seq. ID No. 2947, Seq. ID No. 2981, Seq. ID No. 2983, Seq. ID No. 2987, Seq. ID No. 2991, Seq. ID No. 2995, Seq. ID No. 3001, Seq. ID No. 3005, Seq. ID No. 3021, Seq. ID No. 3025, Seq. ID No. 3043, Seq. ID No. 3045, Seq. ID No. 3073, Seq. ID No. 3075, Seq. ID No. 3155, Seq. ID No. 3163, Seq. ID No. 3165, Seq. ID No. 3167, Seq. ID No. 3183, Seq. ID No. 3213, Seq. ID No. 3215, Seq. ID No. 3235, Seq. ID No. 3245, Seq. ID No. 3261, Seq. ID No. 3263, Seq. ID No. 3265, Seq. ID No. 3269, Seq. ID No. 3271, Seq. ID No. 3275, Seq. ID No. 3277, Seq. ID No. 3317, Seq. ID No. 3325, Seq. ID No. 3337, Seq. ID No. 3351, Seq. ID No. 3389, Seq. ID No. 3405, Seq. ID No. 3419, Seq. ID No. 3421, Seq. ID No. 3423, Seq. ID No. 3451, Seq. ID No. 3453, Seq. ID No. 3455, Seq. ID No. 3491, Seq. ID No. 3495, Seq. ID No. 3503, Seq. ID No. 3505, Seq. ID No. 3517, Seq. ID No. 3519, Seq. ID No. 3545, Seq. ID No. 3547, Seq. ID No. 3571, Seq. ID No. 3593, Seq. ID No. 3617, Seq. ID No. 3621, Seq. ID No. 3629, Seq. ID No. 3663, Seq. ID No. 3701, Seq. ID No. 3703, Seq. ID No. 3723, Seq. ID No. 3737, Seq. ID No. 3741, Seq. ID No. 3745, Seq. ID No. 3747, Seq. ID No. 3759, Seq. ID No. 3763, Seq. ID No. 3767, Seq. ID No. 3769, Seq. ID No. 3771, Seq. ID No. 3785, Seq. ID No. 3793, Seq. ID No. 3813, Seq. ID No. 3837, Seq. ID No. 3839, Seq. ID No. 3861, Seq. ID No. 3865, Seq. ID No. 3889, Seq. ID No. 3891, Seq. ID No. 3895, Seq. ID No. 3915, Seq. ID No. 3923, Seq. ID No. 3925, Seq. ID No. 3929, Seq. ID No. 3965, Seq. ID No. 3975, Seq. ID No. 3979, Seq. ID No. 3995, Seq. ID No. 3997, Seq. ID No. 4009, Seq. ID No. 4039, Seq. ID No. 4041, Seq. ID No. 4061, Seq. ID No. 4079, Seq. ID No. 4081, Seq. ID No. 4111, Seq. ID No. 4113, Seq. ID No. 4135, Seq. ID No. 4139, Seq. ID No. 4155, Seq. ID No. 4181, Seq. ID No. 4203, Seq. ID No. 4221, Seq. ID No. 4247, Seq. ID No. 4253, Seq. ID No. 4257, Seq. ID No. 4259, Seq. ID No. 4261, Seq. ID No. 4263, Seq. ID No. 4269, Seq. ID No. 4311, Seq. ID No. 4379, Seq. ID No. 4389, Seq. ID No. 4391, Seq. ID No. 4471, Seq. ID No. 4473, Seq. ID No. 4481, Seq. ID No. 4525, Seq. ID No. 4551, Seq. ID No. 4561, Seq. ID No. 4573, Seq. ID No. 4617, Seq. ID No. 4639, Seq. ID No. 4659, Seq. ID No. 4681, Seq. ID No. 4701, Seq. ID No. 4705, Seq. ID No. 4713, Seq. ID No. 4717, Seq. ID No. 4721, Seq. ID No. 4737, Seq. ID No. 4741, Seq. ID No. 4813, Seq. ID No. 4817, Seq. ID No. 4819, Seq. ID No. 4829, Seq. ID No. 4831, Seq. ID No. 4851, Seq. ID No. 4869, Seq. ID No. 4875, Seq. ID No. 4913, Seq. ID No. 4919, Seq. ID No. 4929, Seq. ID No. 4931, Seq. ID No. 4983, Seq. ID No. 4993, Seq. ID No. 5011, Seq. ID No. 5023, Seq. ID No. 5031, Seq. ID No. 5033, Seq. ID No. 5035, Seq. ID No. 5043, Seq. ID No. 5061, Seq. ID No. 5063, Seq. ID No. 5069, Seq. ID No. 5103, Seq. ID No. 5121, Seq. ID No. 5123, Seq. ID No. 5131, Seq. ID No. 5133, Seq. ID No. 5135, Seq. ID No. 5137, Seq. ID No. 5139, Seq. ID No. 5141, Seq. ID No. 5151, Seq. ID No. 5159, Seq. ID No. 5161, Seq. ID No. 5165, Seq. ID No. 5167, Seq. ID No. 5175, Seq. ID No. 5177, Seq. ID No. 5205, Seq. ID No. 5207, Seq. ID No. 5211, Seq. ID No. 5215, Seq. ID No. 5219, Seq. ID No. 5223, Seq. ID No. 5285, Seq. ID No. 5287, Seq. ID No. 5329, Seq. ID No. 5331, Seq. ID No. 5377, Seq. ID No. 5379, Seq. ID No. 5381, Seq. ID No. 5385, Seq. ID No. 5405, Seq. ID No. 5407, Seq. ID No. 5453, Seq. ID No. 5459, Seq. ID No. 5461, Seq. ID No. 5463, Seq. ID No. 5481, Seq. ID No. 5509, Seq. ID No. 5529, Seq. ID No. 5531, Seq. ID No. 5557, Seq. ID No. 5569, Seq. ID No. 5577, Seq. ID No. 5623, Seq. ID No. 5625, Seq. ID No. 5643, Seq. ID No. 5659, Seq. ID No. 5661, Seq. ID No. 5683, Seq. ID No. 5685, Seq. ID No. 5709, Seq. ID No. 5711, Seq. ID No. 5733, Seq. ID No. 5739, Seq. ID No. 5765, Seq. ID No. 5797, Seq. ID No. 5827, Seq. ID No. 5889, Seq. ID No. 5893, Seq. ID No. 5905, Seq. ID No. 5909, Seq. ID No. 5911, Seq. ID No. 5923, Seq. ID No. 5963, Seq. ID No. 5965, Seq. ID No. 6025, Seq. ID No. 6027, Seq. ID No. 6031, Seq. ID No. 6043, Seq. ID No. 6045, Seq. ID No. 6047, Seq. ID No. 6053, Seq. ID No. 6059, Seq. ID No. 6109, Seq. ID No. 6111, Seq. ID No. 6115, Seq. ID No. 6117, Seq. ID No. 6127, Seq. ID No. 6131, Seq. ID No. 6135, Seq. ID No. 6137, Seq. ID No. 6161, Seq. ID No. 6165, Seq. ID No. 6183, Seq. ID No. 6189, Seq. ID No. 6191, Seq. ID No. 6193, Seq. ID No. 6207, Seq. ID No. 6209, Seq. ID No. 6217, Seq. ID No. 6225, Seq. ID No. 6235, Seq. ID No. 6243, Seq. ID No. 6249, Seq. ID No. 6253, Seq. ID No. 6259, Seq. ID No. 6265, Seq. ID No. 6267, Seq. ID No. 6275, Seq. ID No. 6283, Seq. ID No. 6285, Seq. ID No. 6303, Seq. ID No. 6325, Seq. ID No. 6327, Seq. ID No. 6363, Seq. ID No. 6365, Seq. ID No. 6367, Seq. ID No. 6385, Seq. ID No. 6425, Seq. ID No. 6427, Seq. ID No. 6429, Seq. ID No. 6431, Seq. ID No. 6453, Seq. ID No. 6465, Seq. ID No. 6469, Seq. ID No. 6471, Seq. ID No. 6479, Seq. ID No. 6539, Seq. ID No. 6541, Seq. ID No. 6571, Seq. ID No. 6573, Seq. ID No. 6639, Seq. ID No. 6643, and Seq. ID No.
 6645. 14. The polynucleotide of claim 7 wherein the polynucleotide encodes a polypeptide, which is predicted by HMM Signal P algorithm analysis as having a signal peptide, and the polynucleotide is selected from one of Seq. ID No. 3, Seq. ID No. 7, Seq. ID No. 9, Seq. ID No. 19, Seq. ID No. 21, Seq. ID No. 31, Seq. ID No. 33, Seq. ID No. 45, Seq. ID No. 47, Seq. ID No. 49, Seq. ID No. 53, Seq. ID No. 65, Seq. ID No. 67, Seq. ID No. 85, Seq. ID No. 87, Seq. ID No. 105, Seq. ID No. 111, Seq. ID No. 123, Seq. ID No. 131, Seq. ID No. 133, Seq. ID No. 141, Seq. ID No. 159, Seq. ID No. 161, Seq. ID No. 163, Seq. ID No. 171, Seq. ID No. 191, Seq. ID No. 209, Seq. ID No. 211, Seq. ID No. 213, Seq. ID No. 215, Seq. ID No. 217, Seq. ID No. 225, Seq. ID No. 235, Seq. ID No. 237, Seq. ID No. 249, Seq. ID No. 251, Seq. ID No. 255, Seq. ID No. 257, Seq. ID No. 259, Seq. ID No. 271, Seq. ID No. 273, Seq. ID No. 277, Seq. ID No. 285, Seq. ID No. 287, Seq. ID No. 289, Seq. ID No. 327, Seq. ID No. 329, Seq. ID No. 357, Seq. ID No. 359, Seq. ID No. 373, Seq. ID No. 375, Seq. ID No. 393, Seq. ID No. 401, Seq. ID No. 403, Seq. ID No. 455, Seq. ID No. 457, Seq. ID No. 477, Seq. ID No. 487, Seq. ID No. 489, Seq. ID No. 491, Seq. ID No. 493, Seq. ID No. 495, Seq. ID No. 497, Seq. ID No. 499, Seq. ID No. 503, Seq. ID No. 505, Seq. ID No. 509, Seq. ID No. 511, Seq. ID No. 513, Seq. ID No. 515, Seq. ID No. 525, Seq. ID No. 527, Seq. ID No. 545, Seq. ID No. 547, Seq. ID No. 549, Seq. ID No. 557, Seq. ID No. 567, Seq. ID No. 569, Seq. ID No. 575, Seq. ID No. 577, Seq. ID No. 579, Seq. ID No. 591, Seq. ID No. 593, Seq. ID No. 599, Seq. ID No. 617, Seq. ID No. 637, Seq. ID No. 639, Seq. ID No. 641, Seq. ID No. 643, Seq. ID No. 645, Seq. ID No. 647, Seq. ID No. 653, Seq. ID No. 655, Seq. ID No. 657, Seq. ID No. 659, Seq. ID No. 661, Seq. ID No. 667, Seq. ID No. 669, Seq. ID No. 675, Seq. ID No. 677, Seq. ID No. 679, Seq. ID No. 715, Seq. ID No. 717, Seq. ID No. 719, Seq. ID No. 721, Seq. ID No. 723, Seq. ID No. 725, Seq. ID No. 745, Seq. ID No. 747, Seq. ID No. 749, Seq. ID No. 751, Seq. ID No. 755, Seq. ID No. 757, Seq. ID No. 759, Seq. ID No. 761, Seq. ID No. 763, Seq. ID No. 765, Seq. ID No. 769, Seq. ID No. 777, Seq. ID No. 779, Seq. ID No. 781, Seq. ID No. 807, Seq. ID No. 809, Seq. ID No. 819, Seq. ID No. 825, Seq. ID No. 863, Seq. ID No. 893, Seq. ID No. 901, Seq. ID No. 935, Seq. ID No. 937, Seq. ID No. 941, Seq. ID No. 943, Seq. ID No. 955, Seq. ID No. 957, Seq. ID No. 967, Seq. ID No. 979, Seq. ID No. 981, Seq. ID No. 983, Seq. ID No. 985, Seq. ID No. 1001, Seq. ID No. 1003, Seq. ID No. 1005, Seq. ID No. 1007, Seq. ID No. 1009, Seq. ID No. 1011, Seq. ID No. 1013, Seq. ID No. 1015, Seq. ID No. 1019, Seq. ID No. 1029, Seq. ID No. 1031, Seq. ID No. 1033, Seq. ID No. 1035, Seq. ID No. 1037, Seq. ID No. 1039, Seq. ID No. 1045, Seq. ID No. 1055, Seq. ID No. 1075, Seq. ID No. 1077, Seq. ID No. 1105, Seq. ID No. 1107, Seq. ID No. 1131, Seq. ID No. 1135, Seq. ID No. 1137, Seq. ID No. 1139, Seq. ID No. 1151, Seq. ID No. 1165, Seq. ID No. 1167, Seq. ID No. 1169, Seq. ID No. 1173, Seq. ID No. 1183, Seq. ID No. 1195, Seq. ID No. 1197, Seq. ID No. 1203, Seq. ID No. 1213, Seq. ID No. 1223, Seq. ID No. 1227, Seq. ID No. 1229, Seq. ID No. 1237, Seq. ID No. 1243, Seq. ID No. 1245, Seq. ID No. 1259, Seq. ID No. 1265, Seq. ID No. 1267, Seq. ID No. 1269, Seq. ID No. 1271, Seq. ID No. 1283, Seq. ID No. 1287, Seq. ID No. 1289, Seq. ID No. 1291, Seq. ID No. 1295, Seq. ID No. 1297, Seq. ID No. 1303, Seq. ID No. 1305, Seq. ID No. 1315, Seq. ID No. 1317, Seq. ID No. 1319, Seq. ID No. 1325, Seq. ID No. 1327, Seq. ID No. 1329, Seq. ID No. 1331, Seq. ID No. 1337, Seq. ID No. 1341, Seq. ID No. 1343, Seq. ID No. 1347, Seq. ID No. 1349, Seq. ID No. 1351, Seq. ID No. 1353, Seq. ID No. 1365, Seq. ID No. 1367, Seq. ID No. 1369, Seq. ID No. 1371, Seq. ID No. 1381, Seq. ID No. 1401, Seq. ID No. 1429, Seq. ID No. 1435, Seq. ID No. 1445, Seq. ID No. 1447, Seq. ID No. 1481, Seq. ID No. 1513, Seq. ID No. 1515, Seq. ID No. 1517, Seq. ID No. 1529, Seq. ID No. 1533, Seq. ID No. 1535, Seq. ID No. 1545, Seq. ID No. 1547, Seq. ID No. 1551, Seq. ID No. 1553, Seq. ID No. 1559, Seq. ID No. 1561, Seq. ID No. 1563, Seq. ID No. 1571, Seq. ID No. 1579, Seq. ID No. 1583, Seq. ID No. 1585, Seq. ID No. 1621, Seq. ID No. 1633, Seq. ID No. 1639, Seq. ID No. 1643, Seq. ID No. 1645, Seq. ID No. 1647, Seq. ID No. 1649, Seq. ID No. 1653, Seq. ID No. 1661, Seq. ID No. 1663, Seq. ID No. 1665, Seq. ID No. 1671, Seq. ID No. 1673, Seq. ID No. 1677, Seq. ID No. 1679, Seq. ID No. 1681, Seq. ID No. 1693, Seq. ID No. 1707, Seq. ID No. 1711, Seq. ID No. 1731, Seq. ID No. 1733, Seq. ID No. 1737, Seq. ID No. 1753, Seq. ID No. 1755, Seq. ID No. 1757, Seq. ID No. 1765, Seq. ID No. 1767, Seq. ID No. 1771, Seq. ID No. 1781, Seq. ID No. 1787, Seq. ID No. 1791, Seq. ID No. 1797, Seq. ID No. 1805, Seq. ID No. 1819, Seq. ID No. 1821, Seq. ID No. 1823, Seq. ID No. 1839, Seq. ID No. 1857, Seq. ID No. 1869, Seq. ID No. 1875, Seq. ID No. 1891, Seq. ID No. 1893, Seq. ID No. 1895, Seq. ID No. 1915, Seq. ID No. 1917, Seq. ID No. 1919, Seq. ID No. 1923, Seq. ID No. 1927, Seq. ID No. 1929, Seq. ID No. 1969, Seq. ID No. 1981, Seq. ID No. 1991, Seq. ID No. 1993, Seq. ID No. 2005, Seq. ID No. 2013, Seq. ID No. 2017, Seq. ID No. 2019, Seq. ID No. 2025, Seq. ID No. 2027, Seq. ID No. 2033, Seq. ID No. 2035, Seq. ID No. 2041, Seq. ID No. 2049, Seq. ID No. 2053, Seq. ID No. 2055, Seq. ID No. 2087, Seq. ID No. 2089, Seq. ID No. 2091, Seq. ID No. 2105, Seq. ID No. 2107, Seq. ID No. 2109, Seq. ID No. 2113, Seq. ID No. 2115, Seq. ID No. 2121, Seq. ID No. 2123, Seq. ID No. 2125, Seq. ID No. 2127, Seq. ID No. 2149, Seq. ID No. 2151, Seq. ID No. 2155, Seq. ID No. 2157, Seq. ID No. 2159, Seq. ID No. 2171, Seq. ID No. 2173, Seq. ID No. 2177, Seq. ID No. 2187, Seq. ID No. 2191, Seq. ID No. 2205, Seq. ID No. 2237, Seq. ID No. 2239, Seq. ID No. 2245, Seq. ID No. 2249, Seq. ID No. 2251, Seq. ID No. 2255, Seq. ID No. 2259, Seq. ID No. 2271, Seq. ID No. 2283, Seq. ID No. 2289, Seq. ID No. 2291, Seq. ID No. 2293, Seq. ID No. 2295, Seq. ID No. 2303, Seq. ID No. 2305, Seq. ID No. 2307, Seq. ID No. 2317, Seq. ID No. 2319, Seq. ID No. 2321, Seq. ID No. 2323, Seq. ID No. 2325, Seq. ID No. 2327, Seq. ID No. 2329, Seq. ID No. 2333, Seq. ID No. 2343, Seq. ID No. 2347, Seq. ID No. 2349, Seq. ID No. 2351, Seq. ID No. 2353, Seq. ID No. 2355, Seq. ID No. 2357, Seq. ID No. 2365, Seq. ID No. 2367, Seq. ID No. 2371, Seq. ID No. 2375, Seq. ID No. 2387, Seq. ID No. 2389, Seq. ID No. 2391, Seq. ID No. 2393, Seq. ID No. 2407, Seq. ID No. 2419, Seq. ID No. 2421, Seq. ID No. 2425, Seq. ID No. 2427, Seq. ID No. 2429, Seq. ID No. 2433, Seq. ID No. 2449, Seq. ID No. 2459, Seq. ID No. 2487, Seq. ID No. 2489, Seq. ID No. 2491, Seq. ID No. 2493, Seq. ID No. 2497, Seq. ID No. 2499, Seq. ID No. 2501, Seq. ID No. 2503, Seq. ID No. 2507, Seq. ID No. 2515, Seq. ID No. 2517, Seq. ID No. 2523, Seq. ID No. 2525, Seq. ID No. 2527, Seq. ID No. 2531, Seq. ID No. 2533, Seq. ID No. 2535, Seq. ID No. 2537, Seq. ID No. 2541, Seq. ID No. 2543, Seq. ID No. 2545, Seq. ID No. 2555, Seq. ID No. 2557, Seq. ID No. 2565, Seq. ID No. 2569, Seq. ID No. 2571, Seq. ID No. 2583, Seq. ID No. 2591, Seq. ID No. 2597, Seq. ID No. 2599, Seq. ID No. 2601, Seq. ID No. 2607, Seq. ID No. 2611, Seq. ID No. 2621, Seq. ID No. 2627, Seq. ID No. 2629, Seq. ID No. 2651, Seq. ID No. 2679, Seq. ID No. 2681, Seq. ID No. 2683, Seq. ID No. 2691, Seq. ID No. 2693, Seq. ID No. 2695, Seq. ID No. 2697, Seq. ID No. 2699, Seq. ID No. 2701, Seq. ID No. 2703, Seq. ID No. 2705, Seq. ID No. 2707, Seq. ID No. 2717, Seq. ID No. 2729, Seq. ID No. 2731, Seq. ID No. 2733, Seq. ID No. 2783, Seq. ID No. 2785, Seq. ID No. 2801, Seq. ID No. 2809, Seq. ID No. 2813, Seq. ID No. 2815, Seq. ID No. 2819, Seq. ID No. 2821, Seq. ID No. 2823, Seq. ID No. 2831, Seq. ID No. 2833, Seq. ID No. 2835, Seq. ID No. 2837, Seq. ID No. 2839, Seq. ID No. 2841, Seq. ID No. 2845, Seq. ID No. 2853, Seq. ID No. 2855, Seq. ID No. 2859, Seq. ID No. 2861, Seq. ID No. 2873, Seq. ID No. 2881, Seq. ID No. 2893, Seq. ID No. 2905, Seq. ID No. 2935, Seq. ID No. 2937, Seq. ID No. 2939, Seq. ID No. 2941, Seq. ID No. 2947, Seq. ID No. 2949, Seq. ID No. 2951, Seq. ID No. 2969, Seq. ID No. 2973, Seq. ID No. 2975, Seq. ID No. 2977, Seq. ID No. 2981, Seq. ID No. 2983, Seq. ID No. 2987, Seq. ID No. 2991, Seq. ID No. 2995, Seq. ID No. 2997, Seq. ID No. 3005, Seq. ID No. 3007, Seq. ID No. 3009, Seq. ID No. 3011, Seq. ID No. 3013, Seq. ID No. 3023, Seq. ID No. 3025, Seq. ID No. 3027, Seq. ID No. 3029, Seq. ID No. 3031, Seq. ID No. 3043, Seq. ID No. 3055, Seq. ID No. 3063, Seq. ID No. 3071, Seq. ID No. 3073, Seq. ID No. 3075, Seq. ID No. 3077, Seq. ID No. 3119, Seq. ID No. 3121, Seq. ID No. 3123, Seq. ID No. 3145, Seq. ID No. 3155, Seq. ID No. 3157, Seq. ID No. 3163, Seq. ID No. 3165, Seq. ID No. 3173, Seq. ID No. 3183, Seq. ID No. 3193, Seq. ID No. 3201, Seq. ID No. 3213, Seq. ID No. 3215, Seq. ID No. 3217, Seq. ID No. 3219, Seq. ID No. 3241, Seq. ID No. 3243, Seq. ID No. 3245, Seq. ID No. 3249, Seq. ID No. 3255, Seq. ID No. 3257, Seq. ID No. 3261, Seq. ID No. 3263, Seq. ID No. 3269, Seq. ID No. 3275, Seq. ID No. 3277, Seq. ID No. 3297, Seq. ID No. 3317, Seq. ID No. 3323, Seq. ID No. 3325, Seq. ID No. 3331, Seq. ID No. 3335, Seq. ID No. 3337, Seq. ID No. 3339, Seq. ID No. 3349, Seq. ID No. 3351, Seq. ID No. 3353, Seq. ID No. 3355, Seq. ID No. 3357, Seq. ID No. 3359, Seq. ID No. 3375, Seq. ID No. 3377, Seq. ID No. 3389, Seq. ID No. 3391, Seq. ID No. 3395, Seq. ID No. 3405, Seq. ID No. 3415, Seq. ID No. 3421, Seq. ID No. 3425, Seq. ID No. 3427, Seq. ID No. 3433, Seq. ID No. 3441, Seq. ID No. 3449, Seq. ID No. 3451, Seq. ID No. 3453, Seq. ID No. 3455, Seq. ID No. 3457, Seq. ID No. 3463, Seq. ID No. 3481, Seq. ID No. 3491, Seq. ID No. 3493, Seq. ID No. 3503, Seq. ID No. 3505, Seq. ID No. 3517, Seq. ID No. 3519, Seq. ID No. 3527, Seq. ID No. 3531, Seq. ID No. 3539, Seq. ID No. 3561, Seq. ID No. 3573, Seq. ID No. 3581, Seq. ID No. 3587, Seq. ID No. 3593, Seq. ID No. 3595, Seq. ID No. 3611, Seq. ID No. 3617, Seq. ID No. 3619, Seq. ID No. 3621, Seq. ID No. 3625, Seq. ID No. 3629, Seq. ID No. 3635, Seq. ID No. 3677, Seq. ID No. 3679, Seq. ID No. 3689, Seq. ID No. 3717, Seq. ID No. 3723, Seq. ID No. 3727, Seq. ID No. 3741, Seq. ID No. 3745, Seq. ID No. 3753, Seq. ID No. 3755, Seq. ID No. 3757, Seq. ID No. 3761, Seq. ID No. 3763, Seq. ID No. 3765, Seq. ID No. 3781, Seq. ID No. 3783, Seq. ID No. 3793, Seq. ID No. 3799, Seq. ID No. 3807, Seq. ID No. 3813, Seq. ID No. 3815, Seq. ID No. 3817, Seq. ID No. 3837, Seq. ID No. 3839, Seq. ID No. 3849, Seq. ID No. 3851, Seq. ID No. 3853, Seq. ID No. 3859, Seq. ID No. 3861, Seq. ID No. 3863, Seq. ID No. 3865, Seq. ID No. 3879, Seq. ID No. 3889, Seq. ID No. 3891, Seq. ID No. 3895, Seq. ID No. 3903, Seq. ID No. 3915, Seq. ID No. 3923, Seq. ID No. 3925, Seq. ID No. 3959, Seq. ID No. 3963, Seq. ID No. 3973, Seq. ID No. 3975, Seq. ID No. 3993, Seq. ID No. 3995, Seq. ID No. 3997, Seq. ID No. 4005, Seq. ID No. 4007, Seq. ID No. 4009, Seq. ID No. 4025, Seq. ID No. 4027, Seq. ID No. 4039, Seq. ID No. 4041, Seq. ID No. 4043, Seq. ID No. 4045, Seq. ID No. 4047, Seq. ID No. 4049, Seq. ID No. 4061, Seq. ID No. 4071, Seq. ID No. 4073, Seq. ID No. 4079, Seq. ID No. 4081, Seq. ID No. 4083, Seq. ID No. 4101, Seq. ID No. 4103, Seq. ID No. 4111, Seq. ID No. 4133, Seq. ID No. 4135, Seq. ID No. 4137, Seq. ID No. 4139, Seq. ID No. 4141, Seq. ID No. 4143, Seq. ID No. 4145, Seq. ID No. 4151, Seq. ID No. 4153, Seq. ID No. 4181, Seq. ID No. 4221, Seq. ID No. 4223, Seq. ID No. 4225, Seq. ID No. 4227, Seq. ID No. 4231, Seq. ID No. 4233, Seq. ID No. 4241, Seq. ID No. 4247, Seq. ID No. 4253, Seq. ID No. 4257, Seq. ID No. 4259, Seq. ID No. 4261, Seq. ID No. 4263, Seq. ID No. 4265, Seq. ID No. 4269, Seq. ID No. 4275, Seq. ID No. 4285, Seq. ID No. 4287, Seq. ID No. 4297, Seq. ID No. 4307, Seq. ID No. 4311, Seq. ID No. 4313, Seq. ID No. 4343, Seq. ID No. 4379, Seq. ID No. 4385, Seq. ID No. 4389, Seq. ID No. 4391, Seq. ID No. 4399, Seq. ID No. 4403, Seq. ID No. 4437, Seq. ID No. 4439, Seq. ID No. 4441, Seq. ID No. 4469, Seq. ID No. 4473, Seq. ID No. 4481, Seq. ID No. 4483, Seq. ID No. 4485, Seq. ID No. 4493, Seq. ID No. 4495, Seq. ID No. 4497, Seq. ID No. 4513, Seq. ID No. 4515, Seq. ID No. 4527, Seq. ID No. 4529, Seq. ID No. 4533, Seq. ID No. 4587, Seq. ID No. 4589, Seq. ID No. 4639, Seq. ID No. 4641, Seq. ID No. 4643, Seq. ID No. 4659, Seq. ID No. 4681, Seq. ID No. 4687, Seq. ID No. 4695, Seq. ID No. 4705, Seq. ID No. 4707, Seq. ID No. 4709, Seq. ID No. 4711, Seq. ID No. 4715, Seq. ID No. 4717, Seq. ID No. 4737, Seq. ID No. 4759, Seq. ID No. 4813, Seq. ID No. 4827, Seq. ID No. 4853, Seq. ID No. 4863, Seq. ID No. 4869, Seq. ID No. 4871, Seq. ID No. 4873, Seq. ID No. 4875, Seq. ID No. 4919, Seq. ID No. 4921, Seq. ID No. 4923, Seq. ID No. 4929, Seq. ID No. 4931, Seq. ID No. 4949, Seq. ID No. 4951, Seq. ID No. 4975, Seq. ID No. 4987, Seq. ID No. 4999, Seq. ID No. 5013, Seq. ID No. 5031, Seq. ID No. 5061, Seq. ID No. 5063, Seq. ID No. 5069, Seq. ID No. 5085, Seq. ID No. 5103, Seq. ID No. 5115, Seq. ID No. 5123, Seq. ID No. 5125, Seq. ID No. 5129, Seq. ID No. 5131, Seq. ID No. 5133, Seq. ID No. 5135, Seq. ID No. 5137, Seq. ID No. 5139, Seq. ID No. 5141, Seq. ID No. 5159, Seq. ID No. 5165, Seq. ID No. 5175, Seq. ID No. 5197, Seq. ID No. 5199, Seq. ID No. 5205, Seq. ID No. 5207, Seq. ID No. 5213, Seq. ID No. 5219, Seq. ID No. 5223, Seq. ID No. 5267, Seq. ID No. 5273, Seq. ID No. 5275, Seq. ID No. 5277, Seq. ID No. 5279, Seq. ID No. 5281, Seq. ID No. 5285, Seq. ID No. 5327, Seq. ID No. 5329, Seq. ID No. 5331, Seq. ID No. 5341, Seq. ID No. 5377, Seq. ID No. 5379, Seq. ID No. 5385, Seq. ID No. 5387, Seq. ID No. 5405, Seq. ID No. 5413, Seq. ID No. 5415, Seq. ID No. 5433, Seq. ID No. 5453, Seq. ID No. 5459, Seq. ID No. 5461, Seq. ID No. 5463, Seq. ID No. 5465, Seq. ID No. 5491, Seq. ID No. 5497, Seq. ID No. 5509, Seq. ID No. 5513, Seq. ID No. 5515, Seq. ID No. 5517, Seq. ID No. 5525, Seq. ID No. 5529, Seq. ID No. 5531, Seq. ID No. 5533, Seq. ID No. 5543, Seq. ID No. 5545, Seq. ID No. 5569, Seq. ID No. 5587, Seq. ID No. 5589, Seq. ID No. 5591, Seq. ID No. 5593, Seq. ID No. 5595, Seq. ID No. 5597, Seq. ID No. 5609, Seq. ID No. 5611, Seq. ID No. 5621, Seq. ID No. 5623, Seq. ID No. 5625, Seq. ID No. 5633, Seq. ID No. 5637, Seq. ID No. 5639, Seq. ID No. 5641, Seq. ID No. 5643, Seq. ID No. 5649, Seq. ID No. 5659, Seq. ID No. 5667, Seq. ID No. 5681, Seq. ID No. 5683, Seq. ID No. 5685, Seq. ID No. 5687, Seq. ID No. 5689, Seq. ID No. 5699, Seq. ID No. 5703, Seq. ID No. 5705, Seq. ID No. 5709, Seq. ID No. 5711, Seq. ID No. 5719, Seq. ID No. 5729, Seq. ID No. 5733, Seq. ID No. 5735, Seq. ID No. 5739, Seq. ID No. 5763, Seq. ID No. 5765, Seq. ID No. 5767, Seq. ID No. 5771, Seq. ID No. 5783, Seq. ID No. 5785, Seq. ID No. 5791, Seq. ID No. 5797, Seq. ID No. 5829, Seq. ID No. 5879, Seq. ID No. 5883, Seq. ID No. 5885, Seq. ID No. 5889, Seq. ID No. 5893, Seq. ID No. 5895, Seq. ID No. 5899, Seq. ID No. 5901, Seq. ID No. 5905, Seq. ID No. 5909, Seq. ID No. 5921, Seq. ID No. 5923, Seq. ID No. 5927, Seq. ID No. 5929, Seq. ID No. 5939, Seq. ID No. 6023, Seq. ID No. 6025, Seq. ID No. 6027, Seq. ID No. 6043, Seq. ID No. 6047, Seq. ID No. 6053, Seq. ID No. 6059, Seq. ID No. 6063, Seq. ID No. 6067, Seq. ID No. 6087, Seq. ID No. 6089, Seq. ID No. 6091, Seq. ID No. 6095, Seq. ID No. 6103, Seq. ID No. 6107, Seq. ID No. 6109, Seq. ID No. 6111, Seq. ID No. 6115, Seq. ID No. 6117, Seq. ID No. 6135, Seq. ID No. 6137, Seq. ID No. 6159, Seq. ID No. 6161, Seq. ID No. 6163, Seq. ID No. 6165, Seq. ID No. 6169, Seq. ID No. 6183, Seq. ID No. 6185, Seq. ID No. 6187, Seq. ID No. 6189, Seq. ID No. 6191, Seq. ID No. 6197, Seq. ID No. 6203, Seq. ID No. 6205, Seq. ID No. 6209, Seq. ID No. 6217, Seq. ID No. 6221, Seq. ID No. 6223, Seq. ID No. 6225, Seq. ID No. 6227, Seq. ID No. 6229, Seq. ID No. 6235, Seq. ID No. 6237, Seq. ID No. 6241, Seq. ID No. 6243, Seq. ID No. 6245, Seq. ID No. 6249, Seq. ID No. 6253, Seq. ID No. 6259, Seq. ID No. 6263, Seq. ID No. 6265, Seq. ID No. 6267, Seq. ID No. 6273, Seq. ID No. 6275, Seq. ID No. 6283, Seq. ID No. 6285, Seq. ID No. 6289, Seq. ID No. 6301, Seq. ID No. 6303, Seq. ID No. 6325, Seq. ID No. 6327, Seq. ID No. 6363, Seq. ID No. 6365, Seq. ID No. 6377, Seq. ID No. 6381, Seq. ID No. 6383, Seq. ID No. 6415, Seq. ID No. 6425, Seq. ID No. 6427, Seq. ID No. 6429, Seq. ID No. 6431, Seq. ID No. 6473, Seq. ID No. 6479, Seq. ID No. 6497, Seq. ID No. 6517, Seq. ID No. 6541, Seq. ID No. 6543, Seq. ID No. 6555, Seq. ID No. 6557, Seq. ID No. 6571, Seq. ID No. 6573, Seq. ID No. 6581, Seq. ID No. 6593, Seq. ID No. 6595, Seq. ID No. 6597, Seq. ID No. 6599, Seq. ID No. 6601, Seq. ID No. 6603, Seq. ID No. 6631, Seq. ID No. 6637, Seq. ID No. 6639, Seq. ID No. 6643, Seq. ID No. 6645, and Seq. ID No.
 6649. 15. The polynucleotide of claim 7, wherein the polynucleotide encodes a polypeptide, which is predicted by HMM Signal P algorithm analysis as being a non-secretory protein, and the polynucleotide is selected from one of Seq. ID No. 1, Seq. ID No. 5, Seq. ID No. 11, Seq. ID No. 13, Seq. ID No. 15, Seq. ID No. 17, Seq. ID No. 23, Seq. ID No. 25, Seq. ID No. 27, Seq. ID No. 29, Seq. ID No. 35, Seq. ID No. 37, Seq. ID No. 39, Seq. ID No. 41, Seq. ID No. 43, Seq. ID No. 51, Seq. ID No. 55, Seq. ID No. 57, Seq. ID No. 59, Seq. ID No. 61, Seq. ID No. 63, Seq. ID No. 69, Seq. ID No. 71, Seq. ID No. 73, Seq. ID No. 75, Seq. ID No. 77, Seq. ID No. 79, Seq. ID No. 81, Seq. ID No. 83, Seq. ID No. 89, Seq. ID No. 91, Seq. ID No. 93, Seq. ID No. 95, Seq. ID No. 97, Seq. ID No. 99, Seq. ID No. 101, Seq. ID No. 103, Seq. ID No. 107, Seq. ID No. 109, Seq. ID No. 113, Seq. ID No. 115, Seq. ID No. 117, Seq. ID No. 119, Seq. ID No. 121, Seq. ID No. 125, Seq. ID No. 127, Seq. ID No. 129, Seq. ID No. 135, Seq. ID No. 137, Seq. ID No. 139, Seq. ID No. 143, Seq. ID No. 145, Seq. ID No. 147, Seq. ID No. 149, Seq. ID No. 151, Seq. ID No. 153, Seq. ID No. 155, Seq. ID No. 157, Seq. ID No. 165, Seq. ID No. 167, Seq. ID No. 169, Seq. ID No. 173, Seq. ID No. 175, Seq. ID No. 177, Seq. ID No. 179, Seq. ID No. 181, Seq. ID No. 183, Seq. ID No. 185, Seq. ID No. 187, Seq. ID No. 189, Seq. ID No. 193, Seq. ID No. 195, Seq. ID No. 197, Seq. ID No. 199, Seq. ID No. 201, Seq. ID No. 203, Seq. ID No. 205, Seq. ID No. 207, Seq. ID No. 219, Seq. ID No. 221, Seq. ID No. 223, Seq. ID No. 227, Seq. ID No. 229, Seq. ID No. 231, Seq. ID No. 233, Seq. ID No. 239, Seq. ID No. 241, Seq. ID No. 243, Seq. ID No. 245, Seq. ID No. 247, Seq. ID No. 253, Seq. ID No. 261, Seq. ID No. 263, Seq. ID No. 265, Seq. ID No. 267, Seq. ID No. 269, Seq. ID No. 275, Seq. ID No. 279, Seq. ID No. 281, Seq. ID No. 283, Seq. ID No. 291, Seq. ID No. 293, Seq. ID No. 295, Seq. ID No. 297, Seq. ID No. 299, Seq. ID No. 301, Seq. ID No. 303, Seq. ID No. 305, Seq. ID No. 307, Seq. ID No. 309, Seq. ID No. 311, Seq. ID No. 313, Seq. ID No. 315, Seq. ID No. 317, Seq. ID No. 319, Seq. ID No. 321, Seq. ID No. 323, Seq. ID No. 325, Seq. ID No. 331, Seq. ID No. 333, Seq. ID No. 335, Seq. ID No. 337, Seq. ID No. 339, Seq. ID No. 341, Seq. ID No. 343, Seq. ID No. 345, Seq. ID No. 347, Seq. ID No. 349, Seq. ID No. 351, Seq. ID No. 353, Seq. ID No. 355, Seq. ID No. 361, Seq. ID No. 363, Seq. ID No. 365, Seq. ID No. 367, Seq. ID No. 369, Seq. ID No. 371, Seq. ID No. 377, Seq. ID No. 379, Seq. ID No. 381, Seq. ID No. 383, Seq. ID No. 385, Seq. ID No. 387, Seq. ID No. 389, Seq. ID No. 391, Seq. ID No. 395, Seq. ID No. 397, Seq. ID No. 399, Seq. ID No. 405, Seq. ID No. 407, Seq. ID No. 409, Seq. ID No. 411, Seq. ID No. 413, Seq. ID No. 415, Seq. ID No. 417, Seq. ID No. 419, Seq. ID No. 421, Seq. ID No. 423, Seq. ID No. 425, Seq. ID No. 427, Seq. ID No. 429, Seq. ID No. 431, Seq. ID No. 433, Seq. ID No. 435, Seq. ID No. 437, Seq. ID No. 439, Seq. ID No. 441, Seq. ID No. 443, Seq. ID No. 445, Seq. ID No. 447, Seq. ID No. 449, Seq. ID No. 451, Seq. ID No. 453, Seq. ID No. 459, Seq. ID No. 461, Seq. ID No. 463, Seq. ID No. 465, Seq. ID No. 467, Seq. ID No. 469, Seq. ID No. 471, Seq. ID No. 473, Seq. ID No. 475, Seq. ID No. 479, Seq. ID No. 481, Seq. ID No. 483, Seq. ID No. 485, Seq. ID No. 501, Seq. ID No. 507, Seq. ID No. 517, Seq. ID No. 519, Seq. ID No. 521, Seq. ID No. 523, Seq. ID No. 529, Seq. ID No. 531, Seq. ID No. 533, Seq. ID No. 535, Seq. ID No. 537, Seq. ID No. 539, Seq. ID No. 541, Seq. ID No. 543, Seq. ID No. 551, Seq. ID No. 553, Seq. ID No. 555, Seq. ID No. 559, Seq. ID No. 561, Seq. ID No. 563, Seq. ID No. 565, Seq. ID No. 571, Seq. ID No. 573, Seq. ID No. 581, Seq. ID No. 583, Seq. ID No. 585, Seq. ID No. 587, Seq. ID No. 589, Seq. ID No. 595, Seq. ID No. 597, Seq. ID No. 601, Seq. ID No. 603, Seq. ID No. 605, Seq. ID No. 607, Seq. ID No. 609, Seq. ID No. 611, Seq. ID No. 613, Seq. ID No. 615, Seq. ID No. 619, Seq. ID No. 621, Seq. ID No. 623, Seq. ID No. 625, Seq. ID No. 627, Seq. ID No. 629, Seq. ID No. 631, Seq. ID No. 633, Seq. ID No. 635, Seq. ID No. 649, Seq. ID No. 651, Seq. ID No. 663, Seq. ID No. 665, Seq. ID No. 671, Seq. ID No. 673, Seq. ID No. 681, Seq. ID No. 683, Seq. ID No. 685, Seq. ID No. 687, Seq. ID No. 689, Seq. ID No. 691, Seq. ID No. 693, Seq. ID No. 695, Seq. ID No. 697, Seq. ID No. 699, Seq. ID No. 701, Seq. ID No. 703, Seq. ID No. 705, Seq. ID No. 707, Seq. ID No. 709, Seq. ID No. 711, Seq. ID No. 713, Seq. ID No. 727, Seq. ID No. 729, Seq. ID No. 731, Seq. ID No. 733, Seq. ID No. 735, Seq. ID No. 737, Seq. ID No. 739, Seq. ID No. 741, Seq. ID No. 743, Seq. ID No. 753, Seq. ID No. 767, Seq. ID No. 771, Seq. ID No. 773, Seq. ID No. 775, Seq. ID No. 783, Seq. ID No. 785, Seq. ID No. 787, Seq. ID No. 789, Seq. ID No. 791, Seq. ID No. 793, Seq. ID No. 795, Seq. ID No. 797, Seq. ID No. 799, Seq. ID No. 801, Seq. ID No. 803, Seq. ID No. 805, Seq. ID No. 811, Seq. ID No. 813, Seq. ID No. 815, Seq. ID No. 817, Seq. ID No. 821, Seq. ID No. 823, Seq. ID No. 827, Seq. ID No. 829, Seq. ID No. 831, Seq. ID No. 833, Seq. ID No. 835, Seq. ID No. 837, Seq. ID No. 839, Seq. ID No. 841, Seq. ID No. 843, Seq. ID No. 845, Seq. ID No. 847, Seq. ID No. 849, Seq. ID No. 851, Seq. ID No. 853, Seq. ID No. 855, Seq. ID No. 857, Seq. ID No. 859, Seq. ID No. 861, Seq. ID No. 865, Seq. ID No. 867, Seq. ID No. 869, Seq. ID No. 871, Seq. ID No. 873, Seq. ID No. 875, Seq. ID No. 877, Seq. ID No. 879, Seq. ID No. 881, Seq. ID No. 883, Seq. ID No. 885, Seq. ID No. 887, Seq. ID No. 889, Seq. ID No. 891, Seq. ID No. 895, Seq. ID No. 897, Seq. ID No. 899, Seq. ID No. 903, Seq. ID No. 905, Seq. ID No. 907, Seq. ID No. 909, Seq. ID No. 911, Seq. ID No. 913,Seq. ID No. 915, Seq. ID No. 917, Seq. ID No. 919, Seq. ID No. 921, Seq. ID No. 923, Seq. ID No. 925, Seq. ID No. 927, Seq. ID No. 929, Seq. ID No. 931, Seq. ID No. 933, Seq. ID No. 939, Seq. ID No. 945, Seq. ID No. 947, Seq. ID No. 949, Seq. ID No. 951, Seq. ID No. 953, Seq. ID No. 959, Seq. ID No. 961, Seq. ID No. 963, Seq. ID No. 95, Seq. ID No. 969, Seq. ID No. 971, Seq. ID No. 973, Seq. ID No. 975, Seq. ID No. 977, Seq. ID No. 987, Seq. ID No. 989, Seq. ID No. 991, Seq. ID No. 993, Seq. ID No. 995, Seq. ID No. 997, Seq. ID No. 999, Seq. ID No. 1017, Seq. ID No. 1021, Seq. ID No. 1023, Seq. ID No. 1025, Seq. ID No. 1027, Seq. ID No. 1041, Seq. ID No. 1043, Seq. ID No. 1047, Seq. ID No. 1049, Seq. ID No. 1051, Seq. ID No. 1053, Seq. ID No. 1057, Seq. ID No. 1059, Seq. ID No. 1061, Seq. ID No. 1063, Seq. ID No. 1065, Seq. ID No. 1067, Seq. ID No. 1069, Seq. ID No. 1071, Seq. ID No. 1073, Seq. ID No. 1079, Seq. ID No. 1081, Seq. ID No. 1083, Seq. ID No. 1085, Seq. ID No. 1087, Seq. ID No. 1089, Seq. ID No. 1091, Seq. ID No. 1093, Seq. ID No. 1095, Seq. ID No. 1097, Seq. ID No. 1099, Seq. ID No. 1101, Seq. ID No. 1103, Seq. ID No. 1109, Seq. ID No. 1111, Seq. ID No. 1113, Seq. ID No. 1115, Seq. ID No. 1117, Seq. ID No. 1119, Seq. ID No. 1121, Seq. ID No. 1123, Seq. ID No. 1125, Seq. ID No. 1127, Seq. ID No. 1129, Seq. ID No. 1133, Seq. ID No. 1141, Seq. ID No. 1143, Seq. ID No. 1145, Seq. ID No. 1147, Seq. ID No. 1149, Seq. ID No. 1153, Seq. ID No. 1155, Seq. ID No. 1157, Seq. ID No. 1159, Seq. ID No. 1161, Seq. ID No. 1163, Seq. ID No. 1171, Seq. ID No. 1175, Seq. ID No. 1177, Seq. ID No. 1179, Seq. ID No. 1181, Seq. ID No. 1185, Seq. ID No. 1187, Seq. ID No. 1189, Seq. ID No. 1191, Seq. ID No. 1193, Seq. ID No. 1199, Seq. ID No. 1201, Seq. ID No. 1205, Seq. ID No. 1207, Seq. ID No. 1209, Seq. ID No. 1211, Seq. ID No. 1215, Seq. ID No. 1217, Seq. ID No. 1219, Seq. ID No. 1221, Seq. ID No. 1225, Seq. ID No. 1231, Seq. ID No. 1233, Seq. ID No. 1235, Seq. ID No. 1239, Seq. ID No. 1241, Seq. ID No. 1247, Seq. ID No. 1249, Seq. ID No. 1251, Seq. ID No. 1253, Seq. ID No. 1255, Seq. 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ID No. 1889, Seq. ID No. 1897, Seq. ID No. 1899, Seq. ID No. 1901, Seq. ID No. 1903, Seq. ID No. 1905, Seq. ID No. 1907, Seq. ID No. 1909, Seq. ID No. 1911, Seq. ID No. 1913, Seq. ID No. 1921, Seq. ID No. 1925, Seq. ID No. 1931, Seq. ID No. 1933, Seq. ID No. 1935, Seq. ID No. 1937, Seq. ID No. 1939, Seq. ID No. 1941, Seq. ID No. 1943, Seq. ID No. 1945, Seq. ID No. 1947, Seq. ID No. 1949, Seq. ID No. 1951, Seq. ID No. 1953, Seq. ID No. 1955, Seq. ID No. 1957, Seq. ID No. 1959, Seq. ID No. 1961, Seq. ID No. 1963, Seq. ID No. 1965, Seq. ID No. 1967, Seq. ID No. 1971, Seq. ID No. 1973, Seq. ID No. 1975, Seq. ID No. 1977, Seq. ID No. 1979, Seq. ID No. 1983, Seq. ID No. 1985, Seq. ID No. 1987, Seq. ID No. 1989, Seq. ID No. 1995, Seq. ID No. 1997, Seq. ID No. 1999, Seq. ID No. 2001, Seq. ID No. 2003, Seq. ID No. 2007, Seq. ID No. 2009, Seq. ID No. 2011, Seq. ID No. 2015, Seq. ID No. 2021, Seq. ID No. 2023, Seq. ID No. 2029, Seq. ID No. 2031, Seq. ID No. 2037, Seq. ID No. 2039, Seq. 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ID No. 2573, Seq. ID No. 2575, Seq. ID No. 2577, Seq. ID No. 2579, Seq. ID No. 2581, Seq. ID No. 2585, Seq. ID No. 2587, Seq. ID No. 2589, Seq. ID No. 2593, Seq. ID No. 2595, Seq. ID No. 2603, Seq. ID No. 2605, Seq. ID No. 2609, Seq. ID No. 2613, Seq. ID No. 2615, Seq. ID No. 2617, Seq. ID No. 2619, Seq. ID No. 2623, Seq. ID No. 2625, Seq. ID No. 2631, Seq. ID No. 2633, Seq. ID No, 2635, Seq. ID No. 2637, Seq. ID No. 2639, Seq. ID No. 2641, Seq. ID No. 2643, Seq. ID No. 2645, Seq. ID No. 2647, Seq. ID No. 2649, Seq. ID No. 2653, Seq. ID No. 2655, Seq. ID No. 2657, Seq. ID No. 2659, Seq. ID No. 2661, Seq. ID No. 2663, Seq. ID No. 2665, Seq. ID No. 2667, Seq. ID No. 2669, Seq. ID No. 2671, Seq. ID No. 2673, Seq. ID No. 2675, Seq. ID No. 2677, Seq. ID No. 2685, Seq. ID No. 2687, Seq. ID No. 2689, Seq. ID No. 2709, Seq. ID No. 2711, Seq. ID No. 2713, Seq. ID No. 2715, Seq. ID No. 2719, Seq. ID No. 2721, Seq. ID No. 2723, Seq. ID No. 2725, Seq. ID No. 2727, Seq. ID No. 2735, Seq. 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ID No. 5253, Seq. ID No. 5255, Seq. ID No. 5257, Seq. ID No. 5259, Seq. ID No. 5261, Seq. ID No. 5263, Seq. ID No. 5265, Seq. ID No. 5269, Seq. ID No. 5271, Seq. ID No. 5283, Seq. ID No. 5287, Seq. ID No. 5289, Seq. ID No. 5291, Seq. ID No. 5293, Seq. ID No. 5295, Seq. ID No. 5297, Seq. ID No. 5299, Seq. ID No. 5301, Seq. ID No. 5303, Seq. ID No. 5305, Seq. ID No. 5307, Seq. ID No. 5309, Seq. ID No. 5311, Seq. ID No. 5313, Seq. ID No. 5315, Seq. ID No. 5317, Seq. ID No. 5319, Seq. ID No. 5321, Seq. ID No. 5323, Seq. ID No. 5325, Seq. ID No. 5333, Seq. ID No. 5335, Seq. ID No. 5337, Seq. ID No. 5339, Seq. ID No. 5343, Seq. ID No. 5345, Seq. ID No. 5347, Seq. ID No. 5349, Seq. ID No. 5351, Seq. ID No. 5353, Seq. ID No. 5355, Seq. ID No. 5357, Seq. ID No. 5359, Seq. ID No. 5361, Seq. ID No. 5363, Seq. ID No. 5365, Seq. ID No. 5367, Seq. ID No. 5369, Seq. ID No. 5371, Seq. ID No. 5373, Seq. ID No. 5375, Seq. ID No. 5381, Seq. ID No. 5383, Seq. ID No. 5389, Seq. ID No. 5391, Seq. ID No. 5393, Seq. ID No. 5395, Seq. ID No. 5397, Seq. ID No. 5399, Seq. ID No. 5401, Seq. ID No. 5403, Seq. ID No. 5407, Seq. ID No. 5409, Seq. ID No. 5411, Seq. ID No. 5417, Seq. ID No. 5419, Seq. ID No. 5421, Seq. ID No. 5423, Seq. ID No. 5425, Seq. ID No. 5427, Seq. ID No. 5429, Seq. ID No. 5431, Seq. ID No. 5435, Seq. ID No. 5437, Seq. ID No. 5439, Seq. ID No. 5441, Seq. ID No. 5443, Seq. ID No. 5445, Seq. ID No. 5447, Seq. ID No. 5449, Seq. ID No. 5451, Seq. ID No. 5455, Seq. ID No. 5457, Seq. ID No. 5467, Seq. ID No. 5469, Seq. ID No. 5471, Seq. ID No. 5473, Seq. ID No. 5475, Seq. ID No. 5477, Seq. ID No. 5479, Seq. ID No. 5481, Seq. ID No. 5483, Seq. ID No. 5485, Seq. ID No. 5487, Seq. ID No. 5489, Seq. ID No. 5493, Seq. ID No. 5495, Seq. ID No. 5499, Seq. ID No. 5501, Seq. ID No. 5503, Seq. ID No. 5505, Seq. ID No. 5507, Seq. ID No. 5511, Seq. ID No. 5519, Seq. ID No. 5521, Seq. ID No. 5523, Seq. ID No. 5527, Seq. ID No. 5535, Seq. ID No. 5537, Seq. ID No. 5539, Seq. ID No. 5541, Seq. ID No. 5547, Seq. ID No. 5549, Seq. ID No. 5551, Seq. ID No. 5553, Seq. ID No. 5555, Seq. ID No. 5557, Seq. ID No. 5559, Seq. ID No. 5561, Seq. ID No. 5563, Seq. ID No. 5565, Seq. ID No. 5567, Seq. ID No. 5571, Seq. ID No. 5573, Seq. ID No. 5575, Seq. ID No. 5577, Seq. ID No. 5579, Seq. ID No. 5581, Seq. ID No. 5583, Seq. ID No. 5585, Seq. ID No. 5599, Seq. ID No. 5601, Seq. ID No. 5603, Seq. ID No. 5605, Seq. ID No. 5607, Seq. ID No. 5613, Seq. ID No. 5615, Seq. ID No. 5617, Seq. ID No. 5619, Seq. ID No. 5627, Seq. ID No. 5629, Seq. ID No. 5631, Seq. ID No. 5635, Seq. ID No. 5645, Seq. ID No. 5647, Seq. ID No. 5651, Seq. ID No. 5653, Seq. ID No. 5655, Seq. ID No. 5657, Seq. ID No. 5661, Seq. ID No. 5663, Seq. ID No. 5665, Seq. ID No. 5669, Seq. ID No. 5671, Seq. ID No. 5673, Seq. ID No. 5675, Seq. ID No. 5677, Seq. ID No. 5679, Seq. ID No. 5691, Seq. ID No. 5693, Seq. ID No. 5695, Seq. ID No. 5697, Seq. ID No. 5701, Seq. ID No. 5707, Seq. ID No. 5713, Seq. ID No. 5715, Seq. ID No. 5717, Seq. ID No. 5721, Seq. ID No. 5723, Seq. ID No. 5725, Seq. ID No. 5727, Seq. ID No. 5731, Seq. ID No. 5737, Seq. ID No. 5741, Seq. ID No. 5743, Seq. ID No. 5745, Seq. ID No. 5747, Seq. ID No. 5749, Seq. ID No. 5751, Seq. ID No. 5753, Seq. ID No. 5755, Seq. ID No. 5757, Seq. ID No. 5759, Seq. ID No. 5761, Seq. ID No. 5769, Seq. ID No. 5773, Seq. ID No. 5775, Seq. ID No. 5777, Seq. ID No. 5779, Seq. ID No. 5781, Seq. ID No. 5787, Seq. ID No. 5789, Seq. ID No. 5793, Seq. ID No. 5795, Seq. ID No. 5799, Seq. ID No. 5801, Seq. ID No. 5803, Seq. ID No. 5805, Seq. ID No. 5807, Seq. ID No. 5809, Seq. ID No. 5811, Seq. ID No. 5813, Seq. ID No. 5815, Seq. ID No. 5817, Seq. ID No. 5819, Seq. ID No. 5821, Seq. ID No. 5823, Seq. ID No. 5825, Seq. ID No. 5827, Seq. ID No. 5831, Seq. ID No. 5833, Seq. ID No. 5835, Seq. ID No. 5837, Seq. ID No. 5839, Seq. ID No. 5841, Seq. ID No. 5843, Seq. ID No. 5845, Seq. ID No. 5847, Seq. ID No. 5849, Seq. ID No. 5851, Seq. ID No. 5853, Seq. ID No. 5855, Seq. ID No. 5857, Seq. ID No. 5859, Seq. ID No. 5861, Seq. ID No. 5863, Seq. ID No. 5865, Seq. ID No. 5867, Seq. ID No. 5869, Seq. ID No. 5871, Seq. ID No. 5873, Seq. ID No. 5875, Seq. ID No. 5877, Seq. ID No. 5881, Seq. ID No. 5887, Seq. ID No. 5891, Seq. ID No. 5897, Seq. ID No. 5903, Seq. ID No. 5907, Seq. ID No. 5911, Seq. ID No. 5913, Seq. ID No. 5915, Seq. ID No. 5917, Seq. ID No. 5919, Seq. ID No. 5925, Seq. ID No. 5931, Seq. ID No. 5933, Seq. ID No. 5935, Seq. ID No. 5937, Seq. ID No. 5941, Seq. ID No. 5943, Seq. ID No. 5945, Seq. ID No. 5947, Seq. ID No. 5949, Seq. ID No. 5951, Seq. ID No. 5953, Seq. ID No. 5955, Seq. ID No. 5957, Seq. ID No. 5959, Seq. ID No. 5961, Seq. ID No. 5963, Seq. ID No. 5965, Seq. ID No. 5967, Seq. ID No. 5969, Seq. ID No. 5971, Seq. ID No. 5973, Seq. ID No. 5975, Seq. ID No. 5977, Seq. ID No. 5979, Seq. ID No. 5981, Seq. ID No. 5983, Seq. ID No. 5985, Seq. ID No. 5987, Seq. ID No. 5989, Seq. ID No. 5991, Seq. ID No. 5993, Seq. ID No. 5995, Seq. ID No. 5997, Seq. ID No. 5999, Seq. ID No. 6001, Seq. ID No. 6003, Seq. ID No. 6005, Seq. ID No. 6007, Seq. ID No. 6009, Seq. ID No. 6011, Seq. ID No. 6013, Seq. ID No. 6015, Seq. ID No. 6017, Seq. ID No. 6019, Seq. ID No. 6021, Seq. ID No. 6029, Seq. ID No. 6031, Seq. ID No. 6033, Seq. ID No. 6035, Seq. ID No. 6037, Seq. ID No. 6039, Seq. ID No. 6041, Seq. ID No. 6045, Seq. ID No. 6049, Seq. ID No. 6051, Seq. ID No. 6055, Seq. ID No. 6057, Seq. ID No. 6061, Seq. ID No. 6065, Seq. ID No. 6069, Seq. ID No. 6071, Seq. ID No. 6073, Seq. ID No. 6075, Seq. ID No. 6077, Seq. ID No. 6079, Seq. ID No. 6081, Seq. ID No. 6083, Seq. ID No. 6085, Seq. ID No. 6093, Seq. ID No. 6097, Seq. ID No. 6099, Seq. ID No. 6101, Seq. ID No. 6105, Seq. ID No. 6113, Seq. ID No. 6119, Seq. ID No. 6121, Seq. ID No. 6123, Seq. ID No. 6125, Seq. ID No. 6127, Seq. ID No. 6129, Seq. ID No. 6131, Seq. ID No. 6133, Seq. ID No. 6139, Seq. ID No. 6141, Seq. ID No. 6143, Seq. ID No. 6145, Seq. ID No. 6147, Seq. ID No. 6149, Seq. ID No. 6151, Seq. ID No. 6153, Seq. ID No. 6155, Seq. ID No. 6157, Seq. ID No. 6167, Seq. ID No. 6171, Seq. ID No. 6173, Seq. ID No. 6175, Seq. ID No. 6177, Seq. ID No. 6179, Seq. ID No. 6181, Seq. ID No. 6193, Seq. ID No. 6195, Seq. ID No. 6199, Seq. ID No. 6201, Seq. ID No. 6207, Seq. ID No. 6211, Seq. ID No. 6213, Seq. ID No. 6215, Seq. ID No. 6219, Seq. ID No. 6231, Seq. ID No. 6233, Seq. ID No. 6239, Seq. ID No. 6247, Seq. ID No. 6251, Seq. ID No. 6255, Seq. ID No. 6257, Seq. ID No. 6261, Seq. ID No. 6269, Seq. ID No. 6271, Seq. ID No. 6277, Seq. ID No. 6279, Seq. ID No. 6281, Seq. ID No. 6287, Seq. ID No. 6291, Seq. ID No. 6293, Seq. ID No. 6295, Seq. ID No. 6297, Seq. ID No. 6299, Seq. ID No. 6305, Seq. ID No. 6307, Seq. ID No. 6309, Seq. ID No. 6311, Seq. ID No. 6313, Seq. ID No. 6315, Seq. ID No. 6317, Seq. ID No. 6319, Seq. ID No. 6321, Seq. ID No. 6323, Seq. ID No. 6329, Seq. ID No. 6331, Seq. ID No. 6333, Seq. ID No. 6335, Seq. ID No. 6337, Seq. ID No. 6339, Seq. ID No. 6341, Seq. ID No. 6343, Seq. ID No. 6345, Seq. ID No. 6347, Seq. ID No. 6349, Seq. ID No. 6351, Seq. ID No. 6353, Seq. ID No. 6355, Seq. ID No. 6357, Seq. ID No. 6359, Seq. ID No. 6361, Seq. ID No. 6367, Seq. ID No. 6369, Seq. ID No. 6371, Seq. ID No. 6373, Seq. ID No. 6375, Seq. ID No. 6379, Seq. ID No. 6385, Seq. ID No. 6387, Seq. ID No. 6389, Seq. ID No. 6391, Seq. ID No. 6393, Seq. ID No. 6395, Seq. ID No. 6397, Seq. ID No. 6399, Seq. ID No. 6401, Seq. ID No. 6403, Seq. ID No. 6405, Seq. ID No. 6407, Seq. ID No. 6409, Seq. ID No. 6411, Seq. ID No. 6413, Seq. ID No. 6417, Seq. ID No. 6419, Seq. ID No. 6421, Seq. ID No. 6423, Seq. ID No. 6433, Seq. ID No. 6435, Seq. ID No. 6437, Seq. ID No. 6439, Seq. ID No. 6441, Seq. ID No. 6443, Seq. ID No. 6445, Seq. ID No. 6447, Seq. ID No. 6449, Seq. ID No. 6451, Seq. ID No. 6453, Seq. ID No. 6455, Seq. ID No. 6457, Seq. ID No. 6459, Seq. ID No. 6461, Seq. ID No. 6463, Seq. ID No. 6465, Seq. ID No. 467, Seq. ID No. 6469, Seq. ID No. 6471, Seq. ID No. 6475, Seq. ID No. 6477, Seq. ID No. 6481, Seq. ID No. 6483, Seq. ID No. 6485, Seq. ID No. 6487, Seq. ID No. 6489, Seq. ID No. 6491, Seq. ID No. 6493, Seq. ID No. 6495, Seq. ID No. 6499, Seq. ID No. 6501, Seq. ID No. 6503, Seq. ID No. 6505, Seq. ID No. 6507, Seq. ID No. 6509, Seq. ID No. 6511, Seq. ID No. 6513, Seq. ID No. 6515, Seq. ID No. 6519, Seq. ID No. 6521, Seq. ID No. 6523, Seq. ID No. 6525, Seq. ID No. 6527, Seq. ID No. 6529, Seq. ID No. 6531, Seq. ID No. 6533, Seq. ID No. 6535, Seq. ID No. 6537, Seq. ID No. 6539, Seq. ID No. 6545, Seq. ID No. 6547, Seq. ID No. 6549, Seq. ID No. 6551, Seq. ID No. 6553, Seq. ID No. 6559, Seq. ID No. 6561, Seq. ID No. 6563, Seq. ID No. 6565, Seq. ID No. 6567, Seq. ID No. 6569, Seq. ID No. 6575, Seq. ID No. 6577, Seq. ID No. 6579, Seq. ID No. 6583, Seq. ID No. 6585, Seq. ID No. 6587, Seq. ID No. 6589, Seq. ID No. 6591, Seq. ID No. 6605, Seq. ID No. 6607, Seq. ID No. 6609, Seq. ID No. 6611, Seq. ID No. 6613, Seq. ID No. 6615, Seq. ID No. 6617, Seq. ID No. 6619, Seq. ID No. 6621, Seq. ID No. 6623, Seq. ID No. 6625, Seq. ID No. 6627, Seq. ID No. 6629, Seq. ID No. 6633, Seq. ID No. 6635, Seq. ID No. 6641, and Seq. ID No.
 6647. 16. The polynucleotide of claim 7, wherein the polynucleotide encoding a polypeptide is identified by Pfam analysis, and the polynucleotide is selected from one of Seq. ID No. 89, Seq. ID No. 145, Seq. ID No. 155, Seq. ID No. 167, Seq. ID No. 173, Seq. ID No. 191, Seq. ID No. 215, Seq. ID No. 219, Seq. ID No. 221, Seq. ID No. 223, Seq. ID No. 225, Seq. ID No. 233, Seq. ID No. 239, Seq. ID No. 251, Seq. ID No. 253, Seq. ID No. 271, Seq. ID No. 291, Seq. ID No. 331, Seq. ID No. 341, Seq. ID No. 345, Seq. ID No. 375, Seq. ID No. 501, Seq. ID No. 505, Seq. ID No. 511, Seq. ID No. 529, Seq. ID No. 567, Seq. ID No. 569, Seq. ID No. 575, Seq. ID No. 593, Seq. ID No. 595, Seq. ID No. 601, Seq. ID No. 637, Seq. ID No. 649, Seq. ID No. 661, Seq. ID No. 669, Seq. ID No. 675, Seq. ID No. 681, Seq. ID No. 683, Seq. ID No. 729, Seq. ID No. 753, Seq. ID No. 779, Seq. ID No. 827, Seq. ID No. 839, Seq. ID No. 895, Seq. ID No. 939, Seq. ID No. 969, Seq. ID No. 985, Seq. ID No. 1015, Seq. ID No. 1039, Seq. ID No. 1075, Seq. ID No. 1137, Seq. ID No. 1155, Seq. ID No. 1163, Seq. ID No. 1175, Seq. ID No. 1223, Seq. ID No. 1231, Seq. ID No. 1237, Seq. ID No. 1241, Seq. ID No. 1261, Seq. ID No. 1331, Seq. ID No. 1339, Seq. ID No. 1369, Seq. ID No. 1477, Seq. ID No. 1517, Seq. ID No. 1531, Seq. ID No. 1539, Seq. ID No. 1549, Seq. ID No. 1563, Seq. ID No. 1567, Seq. ID No. 1571, Seq. ID No. 1573, Seq. ID No. 1589, Seq. ID No. 1595, Seq. ID No. 1647, Seq. ID No. 1657, Seq. ID No. 1771, Seq. ID No. 1785, Seq. ID No. 1789, Seq. ID No. 1819, Seq. ID No. 1821, Seq. ID No. 1969, Seq. ID No. 2015, Seq. ID No. 2047, Seq. ID No. 2087, Seq. ID No. 2089, Seq. ID No. 2093, Seq. ID No. 2115, Seq. ID No. 2117, Seq. ID No. 2127, Seq. ID No. 2141, Seq. ID No. 2179, Seq. ID No. 2207, Seq. ID No. 2223, Seq. ID No. 2253, Seq. ID No. 2275, Seq. ID No. 2301, Seq. ID No. 2315, Seq. ID No. 2329, Seq. ID No. 2343, Seq. ID No. 2349, Seq. ID No. 2363, Seq. ID No. 2381, Seq. ID No. 2391, Seq. ID No. 2417, Seq. ID No. 2421, Seq. ID No. 2423, Seq. ID No. 2429, Seq. ID No. 2481, Seq. ID No. 2487, Seq. ID No. 2489, Seq. ID No. 2491, Seq. ID No. 2509, Seq. ID No. 2519, Seq. ID No. 2525, Seq. ID No. 2547, Seq. ID No. 2553, Seq. ID No. 2563, Seq. ID No. 2587, Seq. ID No. 2599, Seq. ID No. 2607, Seq. ID No. 2613, Seq. ID No. 2651, Seq. ID No. 2675, Seq. ID No. 2681, Seq. ID No. 2687, Seq. ID No. 2693, Seq. ID No. 2699, Seq. ID No. 2703, Seq. ID No. 2709, Seq. ID No. 2711, Seq. ID No. 2727, Seq. ID No. 2753, Seq. ID No. 2819, Seq. ID No. 2821, Seq. ID No. 2823, Seq. ID No. 2867, Seq. ID No. 2871, Seq. ID No. 2907, Seq. ID No. 2919, Seq. ID No. 2957, Seq. ID No. 2971, Seq. ID No. 2979, Seq. ID No. 2999, Seq. ID No. 3005, Seq. ID No. 3019, Seq. ID No. 3035, Seq. ID No. 3065, Seq. ID No. 3085, Seq. ID No. 3149, Seq. ID No. 3165, Seq. ID No. 3183, Seq. ID No. 3203, Seq. ID No. 3211, Seq. ID No. 3251, Seq. ID No. 3259, Seq. ID No. 3319, Seq. ID No. 3323, Seq. ID No. 3335, Seq. ID No. 3337, Seq. ID No. 3347, Seq. ID No. 3359, Seq. ID No. 3377, Seq. ID No. 3379, Seq. ID No. 3399, Seq. ID No. 3425, Seq. ID No. 3483, Seq. ID No. 3495, Seq. ID No. 3497, Seq. ID No. 3519, Seq. ID No. 3529, Seq. ID No. 3599, Seq. ID No. 3611, Seq. ID No. 3615, Seq. ID No. 3619, Seq. ID No. 3663, Seq. ID No. 3739, Seq. ID No. 3759, Seq. ID No. 3771, Seq. ID No. 3797, Seq. ID No. 3825, Seq. ID No. 3841, Seq. ID No. 3855, Seq. ID No. 3863, Seq. ID No. 3901, Seq. ID No. 3929, Seq. ID No. 4015, Seq. ID No. 4017, Seq. ID No. 4055, Seq. ID No. 4075, Seq. ID No. 4085, Seq. ID No. 4089, Seq. ID No. 4099, Seq. ID No. 4105, Seq. ID No. 4129, Seq. ID No. 4203, Seq. ID No. 4243, Seq. ID No. 4251, Seq. ID No. 4343, Seq. ID No. 4383, Seq. ID No. 4475, Seq. ID No. 4481, Seq. ID No. 4487, Seq. ID No. 4491, Seq. ID No. 4533, Seq. ID No. 4627, Seq. ID No. 4705, Seq. ID No. 4713, Seq. ID No. 4717, Seq. ID No. 4719, Seq. ID No. 4729, Seq. ID No. 4789, Seq. ID No. 4791, Seq. ID No. 4793, Seq. ID No. 4803, Seq. ID No. 4813, Seq. ID No. 4815, Seq. ID No. 4825, Seq. ID No. 4833, Seq. ID No. 4837, Seq. ID No. 4875, Seq. ID No. 4879, Seq. ID No. 4919, Seq. ID No. 4931, Seq. ID No. 4947, Seq. ID No. 4985, Seq. ID No. 5077, Seq. ID No. 5115, Seq. ID No. 5117, Seq. ID No. 5127, Seq. ID No. 5141, Seq. ID No. 5193, Seq. ID No. 5215, Seq. ID No. 5219, Seq. ID No. 5275, Seq. ID No. 5381, Seq. ID No. 5389, Seq. ID No. 5409, Seq. ID No. 5411, Seq. ID No. 5475, Seq. ID No. 5491, Seq. ID No. 5513, Seq. ID No. 5519, Seq. ID No. 5525, Seq. ID No. 5529, Seq. ID No. 5537, Seq. ID No. 5557, Seq. ID No. 5581, Seq. ID No. 5599, Seq. ID No. 5637, Seq. ID No. 5685, Seq. ID No. 5723, Seq. ID No. 5755, Seq. ID No. 5761, Seq. ID No. 5895, Seq. ID No. 5901, Seq. ID No. 5903, Seq. ID No. 5911, Seq. ID No. 5913, Seq. ID No. 5919, Seq. ID No. 5923, Seq. ID No. 5929, Seq. ID No. 6001, Seq. ID No. 6043, Seq. ID No. 6053, Seq. ID No. 6055, Seq. ID No. 6089, Seq. ID No. 6095, Seq. ID No. 6111, Seq. ID No. 6117, Seq. ID No. 6165, Seq. ID No. 6169, Seq. ID No. 6187, Seq. ID No. 6195, Seq. ID No. 6219, Seq. ID No. 6233, Seq. ID No. 6269, Seq. ID No. 6275, Seq. ID No. 6279, Seq. ID No. 6287, Seq. ID No. 6297, Seq. ID No. 6299, Seq. ID No. 6305, Seq. ID No. 6311, Seq. ID No. 6369, Seq. ID No. 6379, Seq. ID No. 6587, and Seq. ID No. 6591
 17. The polynucleotide of claim 7, wherein the polynucleotide encoding a polypeptide is identified by BlastP analysis, and the polynucleotide is selected from one of Seq. ID No. 9, Seq. ID No. 17, Seq. ID No. 45, Seq. ID No. 49, Seq. ID No. 53, Seq. ID No. 59, Seq. ID No. 89, Seq. ID No. 145, Seq. ID No. 157, Seq. ID No. 167, Seq. ID No. 171, Seq. ID No. 191, Seq. ID No. 215, Seq. ID No. 217, Seq. ID No. 225, Seq. ID No. 239, Seq. ID No. 253, Seq. ID No. 273, Seq. ID No. 277, Seq. ID No. 289, Seq. ID. No. 329, Seq. ID No. 343, Seq. ID No. 345, Seq. ID No. 375, Seq. ID No. 501, Seq. ID No. 505, Seq. ID No. 511, Seq. ID No. 515, Seq. ID No. 529, Seq. ID No. 569, Seq. ID No. 575, Seq. ID No. 593, Seq. ID No. 595, Seq. ID No. 637, Seq. ID No. 659, Seq. ID No. 669, Seq. ID No. 675, Seq. ID No. 681, Seq. ID No. 729, Seq. ID No. 779, Seq. ID No. 819, Seq. ID No. 895, Seq. ID No. 921, Seq. ID No. 935, Seq. ID No. 955, Seq. ID No. 967, Seq. ID No. 985, Seq. ID No. 1017, Seq. ID No. 1039, Seq. ID No. 1075, Seq. ID No. 1089, Seq. ID No. 1137, Seq. ID No. 1223, Seq. ID No. 1241, Seq. ID No. 1315, Seq. ID No. 1331, Seq. ID No. 1369, Seq. ID No. 1459, Seq. ID No. 1517, Seq. ID No. 1561, Seq. ID No. 1563, Seq. ID No. 1567, Seq. ID No. 1571, Seq. ID No. 1573, Seq. ID No. 1601, Seq. ID No. 1607, Seq. ID No. 1613, Seq. ID No. 1619, Seq. ID No. 1641, Seq. ID No. 1647, Seq. ID No. 1653, Seq. ID No. 1657, Seq. ID No. 1665, Seq. ID No. 1699, Seq. ID No. 1713, Seq. ID No. 1751, Seq. ID No. 1771, Seq. ID No. 1785, Seq. ID No. 1789, Seq. ID No. 1791, Seq. ID No. 1797, Seq. ID No. 1811, Seq. ID No. 1817, Seq. ID No. 1819, Seq. ID No. 1821, Seq. ID No. 1871, Seq. ID No. 1895, Seq. ID No. 1905, Seq. ID No. 1913, Seq. ID No. 1919, Seq. ID No. 1923, Seq. ID No. 1965, Seq. ID No. 1971, Seq. ID No. 1999, Seq. ID No. 2047, Seq. ID No. 2055, Seq. ID No. 2091, Seq. ID No. 2093, Seq. ID No. 2115, Seq. ID No. 2119, Seq. ID No. 2127, Seq. ID No. 2165, Seq. ID No. 2179, Seq. ID No. 2207, Seq. ID No. 2223, Seq. ID No. 2227, Seq. ID No. 2241, Seq. ID No. 2253, Seq. ID No. 2263, Seq. ID No. 2269, Seq. ID No. 2275, Seq. ID No. 2301, Seq. ID No. 2315, Seq. ID No. 2329, Seq. ID No. 2333, Seq. ID No. 2343, Seq. ID No. 2345, Seq. ID No. 2363, Seq. ID No. 2373, Seq. ID No. 2391, Seq. ID No. 2417, Seq. ID No. 2429, Seq. ID No. 2465, Seq. ID No. 2475, Seq. ID No. 2483, Seq. ID No. 2513, Seq. ID No. 2525, Seq. ID No. 2589, Seq. ID No. 2613, Seq. ID No. 2651, Seq. ID No. 2669, Seq. ID No. 2677, Seq. ID No. 2687, Seq. ID No. 2689, Seq. ID No. 2693, Seq. ID No. 2703, Seq. ID No. 2709, Seq. ID No. 2715, Seq. ID No. 2751, Seq. ID No. 2753, Seq. ID No. 2767, Seq. ID No. 2787, Seq. ID No. 2791, Seq. ID No. 2803, Seq. ID No. 2867, Seq. ID No. 2871, Seq. ID No. 2907, Seq. ID No. 2919, Seq. ID No. 2921, Seq. ID No. 2923, Seq. ID No. 2927, Seq. ID No. 2933, Seq. ID No. 2957, Seq. ID No. 2979, Seq. ID No. 2999, Seq. ID No. 3005, Seq. ID No. 3019, Seq. ID No. 3031, Seq. ID No. 3035, Seq. ID No. 3055, Seq. ID No. 3067, Seq. ID No. 3085, Seq. ID No. 3165, Seq. ID No. 3183, Seq. ID No. 3189, Seq. ID No. 3197, Seq. ID No. 3211, Seq. ID No. 3251, Seq. ID No. 3257, Seq. ID No. 3259, Seq. ID No. 3297, Seq. ID No. 3319, Seq. ID No. 3323, Seq. ID No. 3335, Seq. ID No. 3337, Seq. ID No. 3355, Seq. ID No. 3359, Seq. ID No. 3377, Seq. ID No. 3397, Seq. ID No. 3405, Seq. ID No. 3415, Seq. ID No. 3425, Seq. ID No. 3427, Seq. ID No. 3461, Seq. ID No. 3463, Seq. ID No. 3487, Seq. ID No. 3493, Seq. ID No. 3497, Seq. ID No. 3507, Seq. ID No. 3519, Seq. ID No. 3521, Seq. ID No. 3529, Seq. ID No. 3535, Seq. ID No. 3629, Seq. ID No. 3635, Seq. ID No. 3727, Seq. ID No. 3759, Seq. ID No. 3771, Seq. ID No. 3793, Seq. ID No. 3839, Seq. ID No. 3851, Seq. ID No. 3863, Seq. ID No. 3865, Seq. ID No. 3883, Seq. ID No. 3891, Seq. ID No. 3913, Seq. ID No. 3925, Seq. ID No. 3929, Seq. ID No. 3975, Seq. ID No. 3981, Seq. ID No. 4027, Seq. ID No. 4039, Seq. ID No. 4061, Seq. ID No. 4073, Seq. ID No. 4081, Seq. ID No. 4103, Seq. ID No. 4111, Seq. ID No. 4137, Seq. ID No. 4225, Seq. ID No. 4247, Seq. ID No. 4343, Seq. ID No. 4379, Seq. ID No. 4389, Seq. ID No. 4469, Seq. ID No. 4473, Seq. ID No. 4481, Seq. ID No. 4485, Seq. ID No. 4493, Seq. ID No. 4529, Seq. ID No. 4643, Seq. ID No. 4705, Seq. ID No. 4713, Seq. ID No. 4717, Seq. ID No. 4813, Seq. ID No. 4815, Seq. ID No. 4825, Seq. ID No. 4827, Seq. ID No. 4833, Seq. ID No. 4837, Seq. ID No. 4851, Seq. ID No. 4863, Seq. ID No. 4875, Seq. ID No. 4879, Seq. ID No. 4893, Seq. ID No. 4901, Seq. ID No. 4919, Seq. ID No. 4931, Seq. ID No. 4959, Seq. ID No. 4963, Seq. ID No. 4985, Seq. ID No. 5113, Seq. ID No. 5115, Seq. ID No. 5117, Seq. ID No. 5125, Seq. ID No. 5141, Seq. ID No. 5183, Seq. ID No. 5201, Seq. ID No. 5205, Seq. ID No. 5213, Seq. ID No. 5219, Seq. ID No. 5279, Seq. ID No. 5285, Seq. ID No. 5331, Seq. ID No. 5381, Seq. ID No. 5389, Seq. ID No. 5405, Seq. ID No. 5411, Seq. ID No. 5419, Seq. ID No. 5433, Seq. ID No. 5463, Seq. ID No. 5477, Seq. ID No. 5491, Seq. ID No. 5509, Seq. ID No. 5513, Seq. ID No. 5525, Seq. ID No. 5529, Seq. ID No. 5537, Seq. ID No. 5567, Seq. ID No. 5599, Seq. ID No. 5621, Seq. ID No. 5637, Seq. ID No. 5699, Seq. ID No. 5723, Seq. ID No. 5733, Seq. ID No. 5761, Seq. ID No. 5791, Seq. ID No. 5895, Seq. ID No. 5901, Seq. ID No. 5903, Seq. ID No. 5909, Seq. ID No. 5913, Seq. ID No. 5919, Seq. ID No. 5929, Seq. ID No. 5939, Seq. ID No. 6001, Seq. ID No. 6043, Seq. ID No. 6053, Seq. ID No. 6057, Seq. ID No. 6089, Seq. ID No. 6095, Seq. ID No. 6103, Seq. ID No. 6111, Seq. ID No. 6117, Seq. ID No. 6165, Seq. ID No. 6169, Seq. ID No. 6185, Seq. ID No. 6191, Seq. ID No. 6209, Seq. ID No. 6229, Seq. ID No. 6257, Seq. ID No. 6263, Seq. ID No. 6271, Seq. ID No. 6275, Seq. ID No. 6289, Seq. ID No. 6303, Seq. ID No. 6365, Seq. ID No. 6369, Seq. ID No. 6383, and Seq. ID No.
 6415. 18. The polynucleotide of claim 7, wherein the polynucleotide has been identified using the proteomic methods used for studying surface exposed proteins of Streptococcus pneumoniae as encoding a polypeptide, and the polynucleotide is selected from one of Seq. ID No. 1, Seq. ID No. 5, Seq. ID No. 93, Seq. ID No. 95, Seq. ID No. 103, Seq. ID No. 107, Seq. ID No. 157, Seq. ID No. 223, Seq. ID No. 225, Seq. ID No. 233, Seq. ID No. 239, Seq. ID No. 253, Seq. ID No. 317, Seq. ID No. 321, Seq. ID No. 341, Seq. ID No. 345, Seq. ID No. 353, Seq. ID No. 361, Seq. ID No. 363, Seq. ID No. 365, Seq. ID No. 375, Seq. ID No. 379, Seq. ID No. 383, Seq. ID No. 389, Seq. ID No. 391, Seq. ID No. 397, Seq. ID No. 405, Seq. ID No. 409, Seq. ID No. 415, Seq. ID No. 423, Seq. ID No. 425, Seq. ID No. 427, Seq. ID No. 429, Seq. ID No. 435, Seq. ID No. 437, Seq. ID No. 439, Seq. ID No. 441, Seq. ID No. 443, Seq. ID No. 445, Seq. ID No. 447, Seq. ID No. 449, Seq. ID No. 461, Seq. ID No. 463, Seq. ID No. 465, Seq. ID No. 513, Seq. ID No. 543, Seq. ID No. 551, Seq. ID No. 553, Seq. ID No. 559, Seq. ID No. 595, Seq. ID No. 601, Seq. ID No. 637, Seq. ID No. 649, Seq. ID No. 657, Seq. ID No. 669, Seq. ID No. 675, Seq. ID No. 683, Seq. ID No. 753, Seq. ID No. 929, Seq. ID No. 969, Seq. ID No. 1041, Seq. ID No. 1043, Seq. ID No. 1085, Seq. ID No. 1089, Seq. ID No. 1093, Seq. ID No. 1097, Seq. ID No. 1099, Seq. ID No. 1101, Seq. ID No. 1175, Seq. ID No. 1205, Seq. ID No. 1237, Seq. ID No. 1459, Seq. ID No. 1495, Seq. ID No. 1497, Seq. ID No. 1503, Seq. ID No. 1517, Seq. ID No. 1527, Seq. ID No. 1531, Seq. ID No. 1539, Seq. ID No. 1543, Seq. ID No. 1549, Seq. ID No. 1573, Seq. ID No. 1657, Seq. ID No. 1709, Seq. ID No. 1767, Seq. ID No. 1785, Seq. ID No. 1821, Seq. ID No. 1889, Seq. ID No. 1925, Seq. ID No. 1969, Seq. ID No. 2003, Seq. ID No. 2047, Seq. ID No. 2075, Seq. ID No. 2089, Seq. ID No. 2093, Seq. ID No. 2117, Seq. ID No. 2137, Seq. ID No. 2143, Seq. ID No. 2205, Seq. ID No. 2235, Seq. ID No. 2257, Seq. ID No. 2301, Seq. ID No. 2363, Seq. ID No. 2423, Seq. ID No. 2445, Seq. ID No. 2451, Seq. ID No. 2481, Seq. ID No. 2495, Seq. ID No. 2505, Seq. ID No. 2577, Seq. ID No. 2587, Seq. ID No. 2613, Seq. ID No. 2633, Seq. ID No. 2651, Seq. ID No. 2665, Seq. ID No. 2669, Seq. ID No. 2677, Seq. ID No. 2687, Seq. ID No. 2693, Seq. ID No. 2699, Seq. ID No. 2711, Seq. ID No. 2715, Seq. ID No. 2757, Seq. ID No. 2791, Seq. ID No. 2793, Seq. ID No. 2803, Seq. ID No. 2867, Seq. ID No. 2919, Seq. ID No. 2929, Seq. ID No. 3005, Seq. ID No. 3019, Seq. ID No. 3125, Seq. ID No. 3137, Seq. ID No. 3161, Seq. ID No. 3179, Seq. ID No. 3251, Seq. ID No. 3259, Seq. ID No. 3285, Seq. ID No. 3309, Seq. ID No. 3317, Seq. ID No. 3337, Seq. ID No. 3345, Seq. ID No. 3359, Seq. ID No. 3475, Seq. ID No. 3515, Seq. ID No. 3521, Seq. ID No. 3641, Seq. ID No. 3695, Seq. ID No. 3793, Seq. ID No. 3901, Seq. ID No. 3927, Seq. ID No. 3987, Seq. ID No. 4001, Seq. ID No. 4057, Seq. ID No. 4081, Seq. ID No. 4111, Seq. ID No. 4125, Seq. ID No. 4193, Seq. ID No. 4195, Seq. ID No. 4237, Seq. ID No. 4247, Seq. ID No. 4383, Seq. ID No. 4393, Seq. ID No. 4397, Seq. ID No. 4401, Seq. ID No. 4435, Seq. ID No. 4449, Seq. ID No. 4471, Seq. ID No. 4491, Seq. ID No. 4511, Seq. ID No. 4519, Seq. ID No. 4531, Seq. ID No. 4549, Seq. ID No. 4577, Seq. ID No. 4581, Seq. ID No. 4585, Seq. ID No. 4609, Seq. ID No. 4611, Seq. ID No. 4613, Seq. ID No. 4675, Seq. ID No. 4685, Seq. ID No. 4719, Seq. ID No. 4729, Seq. ID No. 4743, Seq. ID No. 4755, Seq. ID No. 4781, Seq. ID No. 4787, Seq. ID No. 4837, Seq. ID No. 4841, Seq. ID No. 4849, Seq. ID No. 4855, Seq. ID No. 4889, Seq. ID No. 4901, Seq. ID No. 4915, Seq. ID No. 4917, Seq. ID No. 4931, Seq. ID No. 4935, Seq. ID No. 4977, Seq. ID No. 5025, Seq. ID No. 5029, Seq. ID No. 5109, Seq. ID No. 5115, Seq. ID No. 5117, Seq. ID No. 5155, Seq. ID No. 5185, Seq. ID No. 5201, Seq. ID No. 5203, Seq. ID No. 5219, Seq. ID No. 5261, Seq. ID No. 5289, Seq. ID No. 5295, Seq. ID No. 5377, Seq. ID No. 5389, Seq. ID No. 5399, Seq. ID No. 5411, Seq. ID No. 5537, Seq. ID No. 5621, Seq. ID No. 5627, Seq. ID No. 5657, Seq. ID No. 5675, Seq. ID No. 5717, Seq. ID No. 5777, Seq. ID No. 5859, Seq. ID No. 5901, Seq. ID No. 5913, Seq. ID No. 5919, Seq. ID No. 5925, Seq. ID No. 5933, Seq. ID No. 6055, Seq. ID No. 6129, Seq. ID No. 6133, Seq. ID No. 6187, Seq. ID No. 6193, Seq. ID No. 6219, Seq. ID No. 6271, Seq. ID No. 6277, Seq. ID No. 6369, Seq. ID No. 6375, Seq. ID No. 6379, Seq. ID No. 6389, Seq. ID No. 6591, and Seq. ID No.
 6605. 19. The polynucleotide of claim 7, wherein the polypeptide encoded by the polynucleotide was identified using HMM LPXTG motif finder as having a LPXTG motif and wherein the polypeptide is covalently attached to the peptidoglycan layer, and the polynucleotide is selected from one of Seq. ID No. 503, Seq. ID No. 505, Seq. ID No. 1315, Seq. ID No. 1317, Seq. ID No. 1363, Seq. ID No. 1365, Seq. ID No. 1367, Seq. ID No. 1369, Seq. ID No. 1559, Seq. ID No. 1561, Seq. ID No. 1581, Seq. ID No. 1739, Seq. ID No. 1741, Seq. ID No. 2811, Seq. ID No. 2813, Seq. ID No. 3619, Seq. ID No. 5587, Seq. ID No. 5589, Seq. ID No. 5591, Seq. ID No. 5781, Seq. ID No. 5783, and Seq. ID No.
 6103. 20. The polynucleotide of claim 7, wherein the polynucleotide encodes a lipoprotein as predicted by HMM Lipo software program, and the polynucleotide is selected from one of Seq. ID No. 45, Seq. ID No. 47, Seq. ID No. 171, Seq. ID No. 225, Seq. ID No. 419, Seq. ID No. 513, Seq. ID No. 575, Seq. ID No. 591, Seq. ID No. 593, Seq. ID No. 657, Seq. ID No. 659, Seq. ID No. 669, Seq. ID No. 675, Seq. ID No. 745, Seq. ID No. 747, Seq. ID No. 935, Seq. ID No. 1045, Seq. ID No. 1075, Seq. ID No. 1137, Seq. ID No. 1173, Seq. ID No. 1191, Seq. ID No. 1193, Seq. ID No. 1195, Seq. ID No. 1563, Seq. ID No. 1661, Seq. ID No. 1663, Seq. ID No. 1665, Seq. ID No. 1791, Seq. ID No. 1797, Seq. ID No. 1917, Seq. ID No. 1969, Seq. ID No. 2115, Seq. ID No. 2159, Seq. ID No. 2429, Seq. ID No. 2527, Seq. ID No. 2699, Seq. ID No. 2815, Seq. ID No. 2875, Seq. ID No. 2975, Seq. ID No. 2977, Seq. ID No. 2991, Seq. ID No. 3043, Seq. ID No. 3323, Seq. ID No. 3337, Seq. ID No. 4133, Seq. ID No. 4137, Seq. ID No. 4481, Seq. ID No. 4705, Seq. ID No. 4827, Seq. ID No. 4869, Seq. ID No. 5115, Seq. ID No. 5377, Seq. ID No. 5379, Seq. ID No. 5491, Seq. ID No. 5509, Seq. ID No. 5513, Seq. ID No. 5525, Seq. ID No. 5529, Seq. ID No. 5531, Seq. ID No. 5889, Seq. ID No. 5909, Seq. ID No. 6025, Seq. ID No. 6027, Seq. ID No. 6087, Seq. ID No. 6089, Seq. ID No. 6325, Seq. ID No. 6327, Seq. ID No. 6415, Seq. ID No. 6637, Seq. ID No. 6639, and Seq. ID No.
 6645. 21. The polynucleotide of claim 7, wherein the polypeptide encoded by the polynucleotide is predicted by HMM program to be non-covalently bound to the peptidoglycan layer, and the polynucleotide is selected from one of Seq. ID No. 3589, Seq. ID No. 3987, Seq. ID No. 5219, and Seq. ID No.
 5337. 22. The polynucleotide of claim 7, wherein the polynucleotide encodes a polypeptide having a RGDX motif wherein X is not a proline, and the polynucleotide is selected from one of Seq. ID No. 37, Seq. ID No. 99, Seq. ID No. 107, Seq. ID No. 109, Seq. ID No. 111, Seq. ID No. 351, Seq. ID No. 353, Seq. ID No. 465, Seq. ID No. 467, Seq. ID No. 469, Seq. ID No. 471, Seq. ID No. 683, Seq. ID No. 821, Seq. ID No. 823, Seq. ID No. 1021, Seq. ID No. 1023, Seq. ID No. 1157, Seq. ID No. 1159, Seq. ID No. 1233, Seq. ID No. 1333, Seq. ID No. 1335, Seq. ID No. 1449, Seq. ID No. 1559, Seq. ID No. 1561, Seq. ID No. 1563, Seq. ID No. 1625, Seq. ID No. 1777, Seq. ID No. 1827, Seq. ID No. 1829, Seq. ID No. 1871, Seq. ID No. 1925, Seq. ID No. 2135, Seq. ID No. 2145, Seq. ID No. 2173, Seq. ID No. 2175, Seq. ID No. 2177, Seq. ID No. 2179, Seq. ID No. 2259, Seq. ID No. 2317, Seq. ID No. 2319, Seq. ID No. 2321, Seq. ID No. 2323, Seq. ID No. 2325, Seq. ID No. 2327, Seq. ID No. 2329, Seq. ID No. 2401, Seq. ID No. 2671, Seq. ID No. 2863, Seq. ID No. 2869, Seq. ID No. 2919, Seq. ID No. 2921, Seq. ID No. 2993, Seq. ID No. 3087, Seq. ID No. 3137, Seq. ID No. 3279, Seq. ID No. 3281, Seq. ID No. 3283, Seq. ID No. 3333, Seq. ID No. 3335, Seq. ID No. 3497, Seq. ID No. 3499, Seq. ID No. 3501, Seq. ID No. 3533, Seq. ID No. 3671, Seq. ID No. 3673, Seq. ID No. 3675, Seq. ID No. 3837, Seq. ID No. 3839, Seq. ID No. 3841, Seq. ID No. 3843, Seq. ID No. 3929, Seq. ID No. 3961, Seq. ID No. 4037, Seq. ID No. 4193, Seq. ID No. 4239, Seq. ID No. 4327, Seq. ID No. 4329, Seq. ID No. 4333, Seq. ID No. 4393, Seq. ID No. 4463, Seq. ID No. 4465, Seq. ID No. 4467, Seq. ID No. 4597, Seq. ID No. 4629, Seq. ID No. 4631, Seq. ID No. 4675, Seq. ID No. 4677, Seq. ID No. 4679, Seq. ID No. 4689, Seq. ID No. 4691, Seq. ID No. 4693, Seq. ID No. 4781, Seq. ID No. 4799, Seq. ID No. 4801, Seq. ID No. 4803, Seq. ID No. 4861, Seq. ID No. 5009, Seq. ID No. 5143, Seq. ID No. 5145, Seq. ID No. 5179, Seq. ID No. 5181, Seq. ID No. 5183, Seq. ID No. 5249, Seq. ID No. 5251, Seq. ID No. 5253, Seq. ID No. 5259, Seq. ID No. 5261, Seq. ID No. 5293, Seq. ID No. 5295, Seq. ID No. 5297, Seq. ID No. 5299, Seq. ID No. 5307, Seq. ID No. 5309, Seq. ID No. 5411, Seq. ID No. 5535, Seq. ID No. 5537, Seq. ID No. 5745, Seq. ID No. 5821, Seq. ID No. 5823, Seq. ID No. 5825, Seq. ID No. 6029, Seq. ID No. 6171, Seq. ID No. 6307, Seq. ID No. 6309, and Seq. ID No.
 6311. 23. The polynucleotide of claim 7, wherein the polynucleotide encodes a polypeptide that is predicted by BlastP analysis as being involved in capsule biosynthesis and transport, and the polynucleotide is selected from one of Seq. ID No. 49, Seq. ID No. 51, Seq. ID No. 53, Seq. ID No. 59, Seq. ID No. 195, Seq. ID No. 689, Seq. ID No. 703, Seq. ID No. 925, Seq. ID No. 1597, Seq. ID No. 1601, Seq. ID No. 1607, Seq. ID No. 1611, Seq. ID No. 1613, Seq. ID No. 1713, Seq. ID No. 2029, Seq. ID No. 2263, Seq. ID No. 2269, Seq. ID No. 2373, Seq. ID No. 2437, Seq. ID No. 2651, Seq. ID No. 2767, Seq. ID No. 2907, Seq. ID No. 3397, Seq. ID No. 3399, Seq. ID No. 3479, Seq. ID No. 3487, Seq. ID No. 3491, Seq. ID No. 3493, Seq. ID No. 3495, Seq. ID No. 3497, Seq. ID No. 3519, Seq. ID No. 3521, Seq. ID No. 3529, Seq. ID No. 3535, Seq. ID No. 3561, Seq. ID No. 3883, Seq. ID No. 3891, Seq. ID No. 3981, and Seq. ID No.
 4087. 24. The polynucleotide of claim 7, wherein the polynucleotide encodes a polypeptide identified by BlastP analysis as being localized within the capsular loci of the Alloiococcus otitidis genome, and the polynucleotide is selected from one of Seq. ID No. 45, Seq. ID No. 47, Seq. ID No. 51, Seq. ID No. 53, Seq. ID No. 55, Seq. ID No. 57, Seq. ID No. 59, Seq. ID No. 683, Seq. ID No. 685, Seq. ID No. 687, Seq. ID No. 689, Seq. ID No. 691, Seq. ID No. 693, Seq. ID No. 695, Seq. ID No. 697, Seq. ID No. 699, Seq. ID No. 701, Seq. ID N. 703, Seq. ID No. 705, Seq. ID No. 707, Seq. ID No. 709, Seq. ID No. 711, Seq. ID No. 713, Seq. ID No. 715, Seq. ID No. 717, Seq. ID No. 719, Seq. ID No. 721, Seq. ID No. 723, Seq. ID No. 725, Seq. ID No. 727, Seq. ID No. 729, Seq. ID No. 731, Seq. ID No. 733, Seq. ID No. 735, Seq. ID No. 737, Seq. ID No. 739, Seq. ID No. 741, Seq. ID No. 743, Seq. ID No. 745, Seq. ID No. 747, Seq. ID No. 749, Seq. ID No. 751, Seq. ID No. 753, Seq. ID No. 3389, Seq. ID No. 3391, Seq. ID No. 3393, Seq. ID No. 3395, Seq. ID No. 3397, Seq. ID No. 3399, Seq. ID No. 3401, Seq. ID No. 3403, Seq. ID No. 3405, Seq. ID No. 3407, Seq. ID No. 3409, Seq. ID No. 3411, Seq. ID No. 3413, Seq. ID No. 3415, Seq. ID No. 3417, Seq. ID No. 3419, Seq. ID No. 3421, Seq. ID No. 3423, Seq. ID No. 3425, Seq. ID No. 3427, Seq. ID No. 3429, Seq. ID No. 3431, Seq. ID No. 3433, Seq. ID No. 3435, Seq. ID No. 3437, Seq. ID No. 3439, Seq. ID No. 3441, Seq. ID No. 3443, Seq. ID No. 3445, Seq. ID No. 3447, Seq. ID No. 3449, Seq. ID No. 3451, Seq. ID No. 3453, Seq. ID No. 3455, Seq. ID No. 3457, Seq. ID No. 3459, Seq. ID No. 3461, Seq. ID No. 3463, Seq. ID No. 3465, Seq. ID No. 3467, Seq. ID No. 3469, Seq. ID No. 3471, Seq. ID No. 3473, Seq. ID No. 3475, Seq. ID No. 3477, Seq. ID No. 3479, Seq. ID No. 3481, Seq. ID No. 3483, Seq. ID No. 3485, Seq. ID No. 3487, Seq. ID No. 3489, Seq. ID No. 3491, Seq. ID No. 3493, Seq. ID No. 3495, Seq. ID No. 3497, Seq. ID No. 3499, Seq. ID No. 3501, Seq. ID No. 3503, Seq. ID No. 3505, Seq. ID No. 3507, Seq. ID No. 3509, Seq. ID No. 3511, Seq. ID No. 3513, Seq. ID No. 3515, Seq. ID No. 3517, Seq. ID No. 3519, Seq. ID No. 3521, Seq. ID No. 3523, Seq. ID No. 3525, Seq. ID No. 3527, Seq. ID No. 3529, Seq. ID No. 3531, Seq. ID No. 3533, Seq. ID No. 3535, Seq. ID No. 3537, Seq. ID No. 3539, Seq. ID No. 3541, Seq. ID No. 3543, Seq. ID No. 3545, Seq. ID No. 3547, Seq. ID No. 3549, Seq. ID No. 3551, Seq. ID No. 3553, Seq. ID No. 3555, Seq. ID No. 3557, Seq. ID No. 3559, and Seq. ID No.
 3561. 25. The polynucleotide of claim 7, wherein the polynucleotide encodes a polypeptide identified by BlastP analysis as being associated with sporulation, and the polynucleotide is selected from one of Seq. ID No. 1137, Seq. ID No. 1455, Seq. ID No. 2137, Seq. ID No. 2141, Seq. ID No. 2165, Seq. ID No. 2179, Seq. ID No. 2301, Seq. ID No. 2753, Seq. ID No. 4211, Seq. ID No. 4251, Seq. ID No. 4327, Seq. ID No. 4569, Seq. ID No. 4719, and Seq. ID No.
 4729. 26. The polynucleotide of claim 7, wherein the polynucleotide is a unique ORF identified by BlastP analysis as having a BlastP ‘E’ value of >e⁻¹⁰, and the polynucleotide is selected from one of Seq. ID No. 7, Seq. ID No. 19, Seq. ID No. 21, Seq. ID No. 23, Seq. ID No. 31, Seq. ID No. 39, Seq. ID No. 65, Seq. ID No. 67, Seq. ID No. 69, Seq. ID No. 91, Seq. ID No. 99, Seq. ID No. 105, Seq. ID No. 113, Seq. ID No. 115, Seq. ID No. 123, Seq. ID No. 125, Seq. ID No. 127, Seq. ID No. 131, Seq. ID No. 133, Seq. ID No. 139, Seq. ID No. 151, Seq. ID No. 159, Seq. ID No. 161, Seq. ID No. 163, Seq. ID No. 165, Seq. ID No. 169, Seq. ID No. 185, Seq. ID No. 189, Seq. ID No. 193, Seq. ID No. 229, Seq. ID No. 231, Seq. ID No. 255, Seq. ID No. 257, Seq. ID No. 259, Seq. ID No. 275, Seq. ID No. 337, Seq. ID No. 339, Seq. ID No. 347, Seq. ID No. 349, Seq. ID No. 357, Seq. ID No. 359, Seq. ID No. 369, Seq. ID No. 371, Seq. ID No. 377, Seq. ID No. 385, Seq. ID No. 387, Seq. ID No. 393, Seq. ID No. 399, Seq. ID No. 401, Seq. ID No. 403, Seq. ID No. 407, Seq. ID No. 419, Seq. ID No. 431, Seq. ID No. 477, Seq. ID No. 495, Seq. ID No. 507, Seq. ID No. 519, Seq. ID No. 541, Seq. ID No. 545, Seq. ID No. 547, Seq. ID No. 549, Seq. ID No. 557, Seq. ID No. 589, Seq. ID No. 617, Seq. ID No. 619, Seq. ID No. 633, Seq. ID No. 639, Seq. ID No. 641, Seq. ID No. 643, Seq. ID No. 645, Seq. ID No. 647, Seq. ID No. 651, Seq. ID No. 653, Seq. ID No. 655, Seq. ID No. 667, Seq. ID No. 691, Seq. ID No. 693, Seq. ID No. 695, Seq. ID No. 697, Seq. ID No. 715, Seq. ID No. 717, Seq. ID No. 719, Seq. ID No. 731, Seq. ID No. 733, Seq. ID No. 741, Seq. ID No. 743, Seq. ID No. 745, Seq. ID No. 747, Seq. ID No. 749, Seq. ID No. 751, Seq. ID No. 755, Seq. ID No: 757, Seq. ID No. 759, Seq. ID No. 761, Seq. ID No. 763, Seq. ID No. 765, Seq. ID No. 767, Seq. ID No. 801, Seq. ID No. 803, Seq. ID No. 805, Seq. ID No. 807, Seq. ID No. 809, Seq. ID No. 811, Seq. ID No. 813, Seq. ID No. 833, Seq. ID No. 841, Seq. ID No. 849, Seq. ID No. 851, Seq. ID No. 853, Seq. ID No. 855, Seq. ID No. 887, Seq. ID No. 889, Seq. ID No. 891, Seq. ID No. 903, Seq. ID No. 905, Seq. ID No. 909, Seq. ID No. 937, Seq. ID No. 941, Seq. ID No. 943, Seq. ID No. 951, Seq. ID No. 957, Seq. ID No. 973, Seq. ID No. 975, Seq. ID No. 987, Seq. ID No. 1005, Seq. ID No. 1007, Seq. ID No. 1009, Seq. ID No. 1011, Seq. ID No. 1019, Seq. ID No. 1025, Seq. ID No. 1027, Seq. ID No. 1045, Seq. ID No. 1047, Seq. ID No. 1071, Seq. ID No. 1073, Seq. ID No. 1077, Seq. ID No. 1105, Seq. ID No. 1107, Seq. ID No. 1111, Seq. ID No. 1131, Seq. ID No. 1135, Seq. ID No. 1139, Seq. ID No. 1151, Seq. ID No. 1153, Seq. ID No. 1165, Seq. ID No. 1167, Seq. ID No. 1169, Seq. ID No. 1171, Seq. ID No. 1173, Seq. ID No. 1181, Seq. ID No. 1183, Seq. ID No. 1185, Seq. ID No. 1187, Seq. ID No. 1189, Seq. ID No. 1191, Seq. ID No. 1193, Seq. ID No. 1195, Seq. ID No. 1197, Seq. ID No. 1199, Seq. ID No. 1201, Seq. ID No. 1203, Seq. ID No. 1207, Seq. ID No. 1213, Seq. ID No. 1227, Seq. ID No. 1229, Seq. ID No. 1239, Seq. ID No. 1243, Seq. ID No. 1245, Seq. ID No. 1247, Seq. ID No. 1249, Seq. ID No. 1259, Seq. ID No. 1265, Seq. ID No. 1267, Seq. ID No. 1269, Seq. ID No. 1271, Seq. ID No. 1273, Seq. ID No. 1275, Seq. ID No. 1277, Seq. ID No. 1279, Seq. ID No. 1281, Seq. ID No. 1283, Seq. ID No. 1285, Seq. ID No. 1287, Seq. ID No. 1289, Seq. ID No. 1291, Seq. ID No. 1293, Seq. ID No. 1295, Seq. ID No. 1297, Seq. ID No. 1299, Seq. ID No. 1301, Seq. ID No. 1303, Seq. ID No. 1305, Seq. ID No. 1307, Seq. ID No. 1309, Seq. ID No. 1311, Seq. ID No. 1313, Seq. ID No. 1319, Seq. ID No. 1321, Seq. ID No. 1323, Seq. ID No. 1325, Seq. ID No. 1327, Seq. ID No. 1337, Seq. ID No. 1341, Seq. ID No. 1343, Seq. ID No. 1347, Seq. ID No. 1349, Seq. ID No. 1351, Seq. ID No. 1353, Seq. ID No. 1355, Seq. ID No. 1371, Seq. ID No. 1379, Seq. ID No. 1381, Seq. ID No. 1389, Seq. ID No. 1397, Seq. ID No. 1399, Seq. ID No. 1401, Seq. ID No. 1417, Seq. ID No. 1419, Seq. ID No. 1421, Seq. ID No. 1423, Seq. ID No. 1439, Seq. ID No. 1445, Seq. ID No. 1447, Seq. ID No. 1457, Seq. ID No. 1465, Seq. ID No. 1479, Seq. ID No. 1511, Seq. ID No. 1551, Seq. ID No. 1553, Seq. ID No. 1555, Seq. ID No. 1557, Seq. ID No. 1579, Seq. ID No. 1609, Seq. ID No. 1621, Seq. ID No. 1623, Seq. ID No. 1625, Seq. ID No. 1627, Seq. ID No. 1629, Seq. ID No. 1631, Seq. ID No. 1633, Seq. ID No. 1639, Seq. ID No. 1643, Seq. ID No. 1655, Seq. ID No. 1667, Seq. ID No. 1671, Seq. ID No. 1693, Seq. ID No. 1695, Seq. ID No. 1701, Seq. ID No. 1703, Seq. ID No. 1705, Seq. ID No. 1721, Seq. ID No. 1723, Seq. ID No. 1731, Seq. ID No. 1737, Seq. ID No. 1743, Seq. ID No. 1759, Seq. ID No. 1763, Seq. ID No. 1773, Seq. ID No. 1775, Seq. ID No. 1777, Seq. ID No. 1779, Seq. ID No. 1781, Seq. ID No. 1799, Seq. ID No. 1801, Seq. ID No. 1803, Seq. ID No. 1807, Seq. ID No. 1823, Seq. ID No. 1831, Seq. ID No. 1851, Seq. ID No. 1857, Seq. ID No. 1875, Seq. ID No. 1899, Seq. ID No. 1915, Seq. ID No. 1927, Seq. ID No. 1929, Seq. ID No. 1973, Seq. ID No. 1977, Seq. ID No. 1981, Seq. ID No. 2005, Seq. ID No. 2007, Seq. ID No. 2009, Seq. ID No. 2011, Seq. ID No. 2017, Seq. ID No. 2019, Seq. ID No. 2023, Seq. ID No. 2025, Seq. ID No. 2027, Seq. ID No. 2039, Seq. ID No. 2041, Seq. ID No. 2043, Seq. ID No. 2045, Seq. ID No. 2049, Seq. ID No. 2081, Seq. ID No. 2083, Seq. ID No. 2085, Seq. ID No. 2105, Seq. ID No. 2107, Seq. ID No. 2109, Seq. ID No. 2111, Seq. ID No. 2129, Seq. ID No. 2131, Seq. ID No. 2133, Seq. ID No. 2145, Seq. ID No. 2155, Seq. ID No. 2157, Seq. ID No. 2159, Seq. ID No. 2161, Seq. ID No. 2171, Seq. ID No. 2187, Seq. ID No. 2189, Seq. ID No. 2201, Seq. ID No. 2203, Seq. ID No. 2209, Seq. ID No. 2211, Seq. ID No. 2219, Seq. ID No. 2225, Seq. ID No. 2243, Seq. ID No. 2245, Seq. ID No. 2247, Seq. ID No. 2249, Seq. ID No. 2251, Seq. ID No. 2255, Seq. ID No. 2277, Seq. ID No. 2279, Seq. ID No. 2341, Seq. ID No. 2351, Seq. ID No. 2353, Seq. ID No. 2355, Seq. ID No. 2357, Seq. ID No. 2359, Seq. ID No. 2365, Seq. ID No. 2367, Seq. ID No. 2371, Seq. ID No. 2375, Seq. ID No. 2393, Seq. ID No. 2395, Seq. ID No. 2425, Seq. ID No. 2427, Seq. ID No. 2431, Seq. ID No. 2439, Seq. ID No. 2441, Seq. ID No. 2443, Seq. ID No. 2447, Seq. ID No. 2459, Seq. ID No. 2479, Seq. ID No. 2493, Seq. ID No. 2501, Seq. ID No. 2503, Seq. ID No. 2521, Seq. ID No. 2523, Seq. ID No. 2527, Seq. ID No. 2591, Seq. ID No. 2601, Seq. ID No. 2603, Seq. ID No. 2611, Seq. ID No. 2627, Seq. ID No. 2629, Seq. ID No. 2653, Seq. ID No. 2661, Seq. ID No. 2691, Seq. ID No. 2695, Seq. ID No. 2697, Seq. ID No. 2717, Seq. ID No. 2729, Seq. ID No. 2731, Seq. ID No. 2733, Seq. ID No. 2735, Seq. ID No. 2739, Seq. ID No. 2741, Seq. ID No. 2743, Seq. ID No. 2777, Seq. ID No. 2779, Seq. ID No. 2781, Seq. ID No. 2783, Seq. ID No. 2801, Seq. ID No. 2805, Seq. ID No. 2807, Seq. ID No. 2809, Seq. ID No. 2811, Seq. ID No. 2813, Seq. ID No. 2815, Seq. ID No. 2817, Seq. ID No. 2819, Seq. ID No. 2829, Seq. ID No. 2831, Seq. ID No. 2833, Seq. ID No. 2835, Seq. ID No. 2837, Seq. ID No. 2839, Seq. ID No. 2841, Seq. ID No. 2845, Seq. ID No. 2849, Seq. ID No. 2851, Seq. ID No. 2853, Seq. ID No. 2855, Seq. ID No. 2857, Seq. ID No. 2859, Seq. ID No. 2861, Seq. ID No. 2865, Seq. ID No. 2873, Seq. ID No. 2875, Seq. ID No. 2877, Seq. ID No. 2883, Seq. ID No. 2885, Seq. ID No. 2887, Seq. ID No. 2889, Seq. ID No. 2893, Seq. ID No. 2895, Seq. ID No. 2903, Seq. ID No. 2909, Seq. ID No. 2935, Seq. ID No. 2937, Seq. ID No. 2939, Seq. ID No. 2941, Seq. ID No. 2943, Seq. ID No. 2945, Seq. ID No. 2947, Seq. ID No. 2949, Seq. ID No. 2951, Seq. ID No. 2953, Seq. ID No. 2965, Seq. ID No. 2967, Seq. ID No. 2973, Seq. ID No. 2975, Seq. ID No. 2977, Seq. ID No. 2981, Seq. ID No. 2983, Seq. ID No. 2985, Seq. ID No. 2987, Seq. ID No. 2989, Seq. ID No. 2991, Seq. ID No. 3001, Seq. ID No. 3007, Seq. ID No. 3009, Seq. ID No. 3011, Seq. ID No. 3021, Seq. ID No. 3023, Seq. ID No. 3041, Seq. ID No. 3045, Seq. ID No. 3071, Seq. ID No. 3087, Seq. ID No. 3105, Seq. ID No. 3107, Seq. ID No. 3119, Seq. ID No. 3121, Seq. ID No. 3123, Seq. ID No. 3151, Seq. ID No. 3153, Seq. ID No. 3167, Seq. ID No. 3173, Seq. ID No. 3175, Seq. ID No. 3177, Seq. ID No. 3181, Seq. ID No. 3193, Seq. ID No. 3213, Seq. ID No. 3215, Seq. ID No. 3217, Seq. ID No. 3219, Seq. ID No. 3221, Seq. ID No. 3223, Seq. ID No. 3231, Seq. ID No. 3233, Seq. ID No. 3235, Seq. ID No. 3237, Seq. ID No. 3239, Seq. ID No. 3241, Seq. ID No. 3243, Seq. ID No. 3245, Seq. ID No. 3247, Seq. ID No. 3249, Seq. ID No. 3261, Seq. ID No. 3263, Seq. ID No. 3265, Seq. ID No. 3267, Seq. ID No. 3269, Seq. ID No. 3271, Seq. ID No. 3273, Seq. ID No. 3275, Seq. ID No. 3277, Seq. ID No. 3325, Seq. ID No. 3331, Seq. ID No. 3339, Seq. ID No. 3341, Seq. ID No. 3349, Seq. ID No. 3361, Seq. ID No. 3363, Seq. ID No. 3369, Seq. ID No. 3371, Seq. ID No. 3389, Seq. ID No. 3403, Seq. ID No. 3417, Seq. ID No. 3419, Seq. ID No. 3421, Seq. ID No. 3433, Seq. ID No. 3437, Seq. ID No. 3441, Seq. ID No. 3443, Seq. ID No. 3445, Seq. ID No. 3447, Seq. ID No. 3473, Seq. ID No. 3481, Seq. ID No. 3483, Seq. ID No. 3489, Seq. ID No. 3503, Seq. ID No. 3505, Seq. ID No. 3509, Seq. ID No. 3511, Seq. ID No. 3523, Seq. ID No. 3525, Seq. ID No. 3531, Seq. ID No. 3533, Seq. ID No. 3539, Seq. ID No. 3541, Seq. ID No. 3543, Seq. ID No. 3545, Seq. ID No. 3547, Seq. ID No. 3555, Seq. ID No. 3557, Seq. ID No. 3563, Seq. ID No. 3565, Seq. ID No. 3571, Seq. ID No. 3573, Seq. ID No. 3581, Seq. ID No. 3587, Seq. ID No. 3591, Seq. ID No. 3593, Seq. ID No. 3595, Seq. ID No. 3611, Seq. ID No. 3613, Seq. ID No. 3617, Seq. ID No. 3619, Seq. ID No. 3621, Seq. ID No. 3623, Seq. ID No. 3625, Seq. ID No. 3631, Seq. ID No. 3637, Seq. ID No. 3639, Seq. ID No. 3655, Seq. ID No. 3657, Seq. ID No. 3659, Seq. ID No. 3661, Seq. ID No. 3677, Seq. ID No. 3679, Seq. ID No. 3683, Seq. ID No. 3685, Seq. ID No. 3701, Seq. ID No. 3703, Seq. ID No. 3717, Seq. ID No. 3719, Seq. ID No. 3721, Seq. ID No. 3723, Seq. ID No. 3729, Seq. ID No. 3731, Seq. ID No. 3733, Seq. ID No. 3735, Seq. ID No. 3737, Seq. ID No. 3739, Seq. ID No. 3741, Seq. ID No. 3749, Seq. ID No. 3751, Seq. ID No. 3753, Seq. ID No. 3755, Seq. ID No. 3761, Seq. ID No. 3781, Seq. ID No. 3783, Seq. ID No. 3785, Seq. ID No. 3787, Seq. ID No. 3789, Seq. ID No. 3791, Seq. ID No. 3799, Seq. ID No. 3807, Seq. ID No. 3809, Seq. ID No. 3811, Seq. ID No. 3813, Seq. ID No. 3815, Seq. ID No. 3817, Seq. ID No. 3827, Seq. ID No. 3829, Seq. ID No. 3831, Seq. ID No. 3833, Seq. ID No. 3835, Seq. ID No. 3849, Seq. ID No. 3879, Seq. ID No. 3881, Seq. ID No. 3895, Seq. ID No. 3903, Seq. ID No. 3909, Seq. ID No. 3915, Seq. ID No. 3939, Seq. ID No. 3959, Seq. ID No. 3961, Seq. ID No. 3963, Seq. ID No. 3965, Seq. ID No. 3973, Seq. ID No. 3977, Seq. ID No. 3979, Seq. ID No. 3993, Seq. ID No. 3995, Seq. ID No. 3997, Seq. ID No. 4005, Seq. ID No. 4007, Seq. ID No. 4009, Seq. ID No. 4041, Seq. ID No. 4043, Seq. ID No. 4045, Seq. ID No. 4069, Seq. ID No. 4077, Seq. ID No. 4097, Seq. ID No. 4113, Seq. ID No. 4123, Seq. ID No. 4131, Seq. ID No. 4133, Seq. ID No. 4135, Seq. ID No. 4139, Seq. ID No. 4151, Seq. ID No. 4153, Seq. ID No. 4155, Seq. ID No. 4181, Seq. ID No. 4221, Seq. ID No. 4241, Seq. ID No. 4253, Seq. ID No. 4257, Seq. ID No. 4259, Seq. ID No. 4261, Seq. ID No. 4263, Seq. ID No. 4265, Seq. ID No. 4269, Seq. ID No. 4275, Seq. ID No. 4277, Seq. ID No. 4279, Seq. ID No. 4281, Seq. ID No. 4285, Seq. ID No. 4287, Seq. ID No. 4297, Seq. ID No. 4305, Seq. ID No. 4307, Seq. ID No. 4363, Seq. ID No. 4365, Seq. ID No. 4371, Seq. ID No. 4373, Seq. ID No. 4395, Seq. ID No. 4399, Seq. ID No. 4403, Seq. ID No. 4425, Seq. ID No. 4437, Seq. ID No. 4439, Seq. ID No. 4441, Seq. ID No. 4453, Seq. ID No. 4455, Seq. ID No. 4513, Seq. ID No. 4515, Seq. ID No. 4551, Seq. ID No. 4561, Seq. ID No. 4573, Seq. ID No. 4575, Seq. ID No. 4587, Seq. ID No. 4589, Seq. ID No. 4591, Seq. ID No. 4593, Seq. ID No. 4595, Seq. ID No. 4617, Seq. ID No. 4619, Seq. ID No. 4621, Seq. ID No. 4625, Seq. ID No. 4627, Seq. ID No. 4633, Seq. ID No. 4635, Seq. ID No. 4637, Seq. ID No. 4639, Seq. ID No. 4659, Seq. ID No. 4681, Seq. ID No. 4687, Seq. ID No. 4695, Seq. ID No. 4699, Seq. ID No. 4701, Seq. ID No. 4721, Seq. ID No. 4735, Seq. ID No. 4737, Seq. ID No. 4741, Seq. ID No. 4783, Seq. ID No. 4789, Seq. ID No. 4805, Seq. ID No. 4811, Seq. ID No. 4817, Seq. ID No. 4819, Seq. ID No. 4821, Seq. ID No. 4823, Seq. ID No. 4835, Seq. ID No. 4853, Seq. ID No. 4885, Seq. ID No. 4913, Seq. ID No. 4923, Seq. ID No. 4949, Seq. ID No. 4951, Seq. ID No. 4975, Seq. ID No. 4981, Seq. ID No. 4983, Seq. ID No. 4987, Seq. ID No. 4993, Seq. ID No. 4999, Seq. ID No. 5001, Seq. ID No. 5011, Seq. ID No. 5013, Seq. ID No. 5023, Seq. ID No. 5031, Seq. ID No. 5033, Seq. ID No. 5035, Seq. ID No. 5037, Seq. ID No. 5041, Seq. ID No. 5043, Seq. ID No. 5053, Seq. ID No. 5061, Seq. ID No. 5063, Seq. ID No. 5085, Seq. ID No. 5093, Seq. ID No. 5151, Seq. ID No. 5153, Seq. ID No. 5159, Seq. ID No. 5161, Seq. ID No. 5167, Seq. ID No. 5173, Seq. ID No. 5175, Seq. ID No. 5177, Seq. ID No. 5189, Seq. ID No. 5191, Seq. ID No. 5193, Seq. ID No. 5197, Seq. ID No. 5199, Seq. ID No. 5221, Seq. ID No. 5223, Seq. ID No. 5225, Seq. ID No. 5227, Seq. ID No. 5237, Seq. ID No. 5267, Seq. ID No. 5269, Seq. ID No. 5271, Seq. ID No. 5281, Seq. ID No. 5301, Seq. ID No. 5303, Seq. ID No. 5315, Seq. ID No. 5321, Seq. ID No. 5327, Seq. ID No. 5347, Seq. ID No. 5385, Seq. ID No. 5445, Seq. ID No. 5447, Seq. ID No. 5459, Seq. ID No. 5465, Seq. ID No. 5467, Seq. ID No. 5479, Seq. ID No. 5481, Seq. ID No. 5485, Seq. ID No. 5487, Seq. ID No. 5515, Seq. ID No. 5517, Seq. ID No. 5533, Seq. ID No. 5543, Seq. ID No. 5545, Seq. ID No. 5549, Seq. ID No. 5569, Seq. ID No. 5577, Seq. ID No. 5593, Seq. ID No. 5595, Seq. ID No. 5609, Seq. ID No. 5623, Seq. ID No. 5625, Seq. ID No. 5639, Seq. ID No. 5641, Seq. ID No. 5643, Seq. ID No. 5649, Seq. ID No. 5659, Seq. ID No. 5661, Seq. ID No. 5663, Seq. ID No. 5667, Seq. ID No. 5671, Seq. ID No. 5687, Seq. ID No. 5689, Seq. ID No. 5703, Seq. ID No. 5705, Seq. ID No. 5709, Seq. ID No. 5711, Seq. ID No. 5737, Seq. ID No. 5739, Seq. ID No. 5745, Seq. ID No. 5751, Seq. ID No. 5763, Seq. ID No. 5797, Seq. ID No. 5811, Seq. ID No. 5813, Seq. ID No. 5815, Seq. ID No. 5827, Seq. ID No. 5829, Seq. ID No. 5843, Seq. ID No. 5845, Seq. ID No. 5873, Seq. ID No. 5879, Seq. ID No. 5883, Seq. ID No. 5885, Seq. ID No. 5887, Seq. ID No. 5889, Seq. ID No. 5891, Seq. ID No. 5931, Seq. ID No. 5955, Seq. ID No. 5963, Seq. ID No. 5965, Seq. ID No. 5975, Seq. ID No. 5983, Seq. ID No. 5985, Seq. ID No. 5987, Seq. ID No. 5989, Seq. ID No. 6005, Seq. ID No. 6013, Seq. ID No. 6031, Seq. ID No. 6035, Seq. ID No. 6045, Seq. ID No. 6059, Seq. ID No. 6061, Seq. ID No. 6063, Seq. ID No. 6073, Seq. ID No. 6081, Seq. ID No. 6091, Seq. ID No. 6093, Seq. ID No. 6127, Seq. ID No. 6159, Seq. ID No. 6197, Seq. ID No. 6199, Seq. ID No. 6203, Seq. ID No. 6217, Seq. ID No. 6221, Seq. ID No. 6223, Seq. ID No. 6237, Seq. ID No. 6239, Seq. ID No. 6241, Seq. ID No. 6245, Seq. ID No. 6247, Seq. ID No. 6249, Seq. ID No. 6259, Seq. ID No. 6265, Seq. ID No. 6267, Seq. ID No. 6273, Seq. ID No. 6283, Seq. ID No. 6285, Seq. ID No. 6323, Seq. ID No. 6325, Seq. ID No. 6327, Seq. ID No. 6361, Seq. ID No. 6363, Seq. ID No. 6377, Seq. ID No. 6381, Seq. ID No. 6401, Seq. ID No. 6403, Seq. ID No. 6419, Seq. ID No. 6425, Seq. ID No. 6427, Seq. ID No. 6429, Seq. ID No. 6431, Seq. ID No. 6433, Seq. ID No. 6435, Seq. ID No. 6437, Seq. ID No. 6439, Seq. ID No. 6447, Seq. ID No. 6449, Seq. ID No. 6451, Seq. ID No. 6453, Seq. ID No. 6455, Seq. ID No. 6457, Seq. ID No. 6465, Seq. ID No. 6467, Seq. ID No. 6469, Seq. ID No. 6471, Seq. ID No. 6473, Seq. ID No. 6475, Seq. ID No. 6477, Seq. ID No. 6479, Seq. ID No. 6481, Seq. ID No. 6483, Seq. ID No. 6485, Seq. ID No. 6487, Seq. ID No. 6489, Seq. ID No. 6491, Seq. ID No. 6495, Seq. ID No. 6497, Seq. ID No. 6507, Seq. ID No. 6517, Seq. ID No. 6519, Seq. ID No. 6521, Seq. ID No. 6523, Seq. ID No. 6525, Seq. ID No. 6527, Seq. ID No. 6529, Seq. ID No. 6533, Seq. ID No. 6539, Seq. ID No. 6541, Seq. ID No. 6543, Seq. ID No. 6555, Seq. ID No. 6557, Seq. ID No. 6561, Seq. ID No. 6563, Seq. ID No. 6565, Seq. ID No. 6567, Seq. ID No. 6569, Seq. ID No. 6571, Seq. ID No. 6573, Seq. ID No. 6581, Seq. ID No. 6583, Seq. ID No. 6631, Seq. ID No. 6635, Seq. ID No. 6637, Seq. ID No. 6639, Seq. ID No. 6643, Seq. ID No. 6645, Seq. ID No. 6647, and Seq. ID No.
 6649. 27. The polynucleotide of claim 7, wherein the polypeptide encoded by the polynucleotide is identified by GLIMMER™ ORF finder program, and the polynucleotide is selected from one of Seq. ID No. 1, Seq. ID No. 5, Seq. ID No. 11, Seq. ID No. 13, Seq. ID No. 15, Seq. ID No. 17, Seq. ID No. 25, Seq. ID No. 27, Seq. ID No. 29, Seq. ID No. 35, Seq. ID No. 37, Seq. ID No. 41, Seq. ID No. 43, Seq. ID No. 47, Seq. ID No. 51, Seq. ID No. 53, Seq. ID No. 59, Seq. ID No. 63, Seq. ID No. 69, Seq. ID No. 73, Seq. ID No. 75, Seq. ID No. 81, Seq. ID No. 83, Seq. ID No. 89, Seq. ID No. 93, Seq. ID No. 97, Seq. ID No. 103, Seq. ID No. 111, Seq. ID No. 121, Seq. ID No. 125, Seq. ID No. 129, Seq. ID No. 135, Seq. ID No. 137, Seq. ID No. 145, Seq. ID No. 149, Seq. ID No. 157, Seq. ID No. 167, Seq. ID No. 173, Seq. ID No. 183, Seq. ID No. 187, Seq. ID No. 189, Seq. ID No. 191, Seq. ID No. 195, Seq. ID No. 197, Seq. ID No. 203, Seq. ID No. 207, Seq. ID No. 215, Seq. ID No. 219, Seq. ID No. 223, Seq. ID No. 225, Seq. ID No. 227, Seq. ID No. 231, Seq. ID No. 233, Seq. ID No. 239, Seq. ID No. 241, Seq. ID No. 247, Seq. ID No. 253, Seq. ID No. 261, Seq. ID No. 265, Seq. ID No. 269, Seq. ID No. 273, Seq. ID No. 275, Seq. ID No. 277, Seq. ID No. 283, Seq. ID No. 291, Seq. ID No. 293, Seq. ID No. 297, Seq. ID No. 301, Seq. ID No. 307, Seq. ID No. 309, Seq. ID No. 313, Seq. ID No. 317, Seq. ID No. 321, Seq. ID No. 325, Seq. ID No. 335, Seq. ID No. 343, Seq. ID No. 345, Seq. ID No. 353, Seq. ID No. 355, Seq. ID No. 361, Seq. ID No. 363, Seq. ID No. 367, Seq. ID No. 375, Seq. ID No. 379, Seq. ID No. 383, Seq. ID No. 389, Seq. ID No. 391, Seq. ID No. 397, Seq. ID No. 405, Seq. ID No. 411, Seq. ID No. 415, Seq. ID No. 417, Seq. ID No. 423, Seq. ID No. 425, Seq. ID No. 427, Seq. ID No. 429, Seq. ID No. 435, Seq. ID No. 437, Seq. ID No. 439, Seq. ID No. 441, Seq. ID No. 445, Seq. ID No. 447, Seq. ID No. 453, Seq. ID No. 461, Seq. ID No. 463, Seq. ID No. 471, Seq. ID No. 485, Seq. ID No. 501, Seq. ID No. 505, Seq. ID No. 511, Seq. ID No. 515, Seq. ID No. 517, Seq. ID No. 521, Seq. ID No. 523, Seq. ID No. 531, Seq. ID No. 533, Seq. ID No. 539, Seq. ID No. 541, Seq. ID No. 543, Seq. ID No. 551, Seq. ID No. 555, Seq. ID No. 561, Seq. ID No. 565, Seq. ID No. 569, Seq. ID No. 575, Seq. ID No. 579, Seq. ID No. 587, Seq. ID No. 593, Seq. ID No. 597, Seq. ID No. 603, Seq. ID No. 605, Seq. ID No. 609, Seq. ID No. 611, Seq. ID No. 613, Seq. ID No. 615, Seq. ID No. 623, Seq. ID No. 627, Seq. ID No. 629, Seq. ID No. 631, Seq. ID No. 635, Seq. ID No. 637, Seq. ID No. 647, Seq. ID No. 649, Seq. ID No. 661, Seq. ID No. 669, Seq. ID No. 673, Seq. ID No. 675, Seq. ID No. 681, Seq. ID No. 683, Seq. ID No. 689, Seq. ID No. 701, Seq. ID No. 703, Seq. ID No. 709, Seq. ID No. 713, Seq. ID No. 729, Seq. ID No. 733, Seq. ID No. 735, Seq. ID No. 737, Seq. ID No. 741, Seq. ID No. 747, Seq. ID No. 751, Seq. ID No. 753, Seq. ID No. 759, Seq. ID No. 765, Seq. ID No. 767, Seq. ID No. 771, Seq. ID No. 781, Seq. ID No. 783, Seq. ID No. 787, Seq. ID No. 791, Seq. ID No. 795, Seq. ID No. 799, Seq. ID No. 807, Seq. ID No. 817, Seq. ID No. 819, Seq. ID No. 823, Seq. ID No. 827, Seq. ID No. 831, Seq. ID No. 835, Seq. ID No. 837, Seq. ID No. 839, Seq. ID No. 847, Seq. ID No. 851, Seq. ID No. 855, Seq. ID No. 859, Seq. ID No. 867, Seq. ID No. 871, Seq. ID No. 875, Seq. ID No. 881, Seq. ID No. 885, Seq. ID No. 889, Seq. ID No. 891, Seq. ID No. 895, Seq. ID No. 901, Seq. ID No. 907, Seq. ID No. 915, Seq. ID No. 919,Seq. ID No. 925, Seq. ID No. 929, Seq. ID No. 935, Seq. ID No. 939, Seq. ID No. 949, Seq. ID No. 951, Seq. ID No. 955, Seq. ID No. 961, Seq. ID No. 965, Seq. ID No. 967, Seq. ID No. 971, Seq. ID No. 985, Seq. ID No. 993, Seq. ID No. 997, Seq. ID No. 1003, Seq. ID No. 1005, Seq. ID No. 1009, Seq. ID No. 1017, Seq. ID No. 1023, Seq. ID No. 1039, Seq. ID No. 1041, Seq. ID No. 1043, Seq. ID No. 1051, Seq. ID No. 1053, Seq. ID No. 1057, Seq. ID No. 1061, Seq. ID No. 1065, Seq. ID No. 1067, Seq. ID No. 1069, Seq. ID No. 1073, Seq. ID No. 1075, Seq. ID No. 1083, Seq. ID No. 1087, Seq. ID No. 1091, Seq. ID No. 1093, Seq. ID No. 1097, Seq. ID No. 1099, Seq. ID No. 1103, Seq. ID No. 1109, Seq. ID No. 1115, Seq. ID No.1117, Seq. ID No. 1123, Seq. ID No. 1129, Seq. ID No. 1133, Seq. ID No. 1137, Seq. ID No. 1143, Seq. ID No. 1147, Seq. ID No. 1149, Seq. ID No. 1155, Seq. ID No. 1157, Seq. ID No. 1159, Seq. ID No. 1163, Seq. ID No. 1171, Seq. ID No. 1179, Seq. ID No. 1181, Seq. ID No. 1187, Seq. ID No. 1193, Seq. ID No. 1199, Seq. ID No. 1205, Seq. ID No. 1211, Seq. ID No. 1217, Seq. ID No. 1221, Seq. ID No. 1223, Seq. ID No. 1225, Seq. ID No. 1231, Seq. ID No. 1233, Seq. ID No. 1237, Seq. ID No. 1241, Seq. ID No. 1253, Seq. ID No. 1257, Seq. ID No. 1263, Seq. ID No. 1271, Seq. ID No. 1281, Seq. ID No. 1317, Seq. ID No. 1323, Seq. ID No. 1331, Seq. ID No. 1335, Seq. ID No. 1339, Seq. ID No. 1345, Seq. ID No. 1347, Seq. ID No. 1361, Seq. ID No. 1369, Seq. ID No. 1377, Seq. ID No. 1379, Seq. ID No. 1387, Seq. ID No. 1393, Seq. ID No. 1395, Seq. ID No. 1399, Seq. ID No. 1403, Seq. ID No. 1405, Seq. ID No. 1411, Seq. ID No. 1413, Seq. ID No. 1415, Seq. ID No. 1419, Seq. ID No. 1425, Seq. ID No. 1427, Seq. ID No. 1429, Seq. ID No. 1431, Seq. ID No. 1433, Seq. ID No. 1437, Seq. ID No. 1443, Seq. ID No. 1449, Seq. ID No. 1451, Seq. ID No. 1455, Seq. ID No. 1457, Seq. ID No. 1459, Seq. ID No. 1463, Seq. ID No. 1465, Seq. ID No. 1469, Seq. ID No. 1471, Seq. ID No. 1473, Seq. ID No. 1475, Seq. ID No. 1477, Seq. ID No. 1485, Seq. ID No. 1487, Seq. ID No. 1491, Seq. ID No. 1493, Seq. ID No. 1495, Seq. ID No. 1497, Seq. ID No. 1501, Seq. ID No. 1505, Seq. ID No. 1507, Seq. ID No. 1509, Seq. ID No. 1517, Seq. ID No. 1525, Seq. ID No. 1527, Seq. ID No. 1531, Seq. ID No. 1539, Seq. ID No. 1541, Seq. ID No. 1543, Seq. ID No. 1549, Seq. ID No. 1561, Seq. ID No. 1563, Seq. ID No. 1567, Seq. ID No. 1571, Seq. ID No. 1573, Seq. ID No. 1577, Seq. ID No. 1581, Seq. ID No. 1589, Seq. ID No. 1593, Seq. ID No. 1595, Seq. ID No. 1597, Seq. ID No. 1603, Seq. ID No. 1607, Seq. ID No. 1611, Seq. ID No. 1613, Seq. ID No. 1619, Seq. ID No. 1623, Seq. ID No. 1627, Seq. ID No. 1631, Seq. ID No. 1637, Seq. ID No. 1639, Seq. ID No. 1641, Seq. ID No. 1647, Seq. ID No. 1653, Seq. ID No. 1657, Seq. ID No. 1665, Seq. ID No. 1669, Seq. ID No. 1681, Seq. ID No. 1685, Seq. ID No. 1689, Seq. ID No. 1691, Seq. ID No. 1697, Seq. ID No. 1699, Seq. ID No. 1707, Seq. ID No. 1711, Seq. ID No. 1713, Seq. ID No. 1719, Seq. ID No. 1723, Seq. ID No. 1729, Seq. ID No. 1735, Seq. ID No. 1737, Seq. ID No. 1741, Seq. ID No. 1747, Seq. ID No. 1751, Seq. ID No. 1757, Seq. ID No. 1759, Seq. ID No. 1761, Seq. ID No. 1771, Seq. ID No. 1777, Seq. ID No. 1785, Seq. ID No. 1789, Seq. ID No. 1791, Seq. ID No. 1797, Seq. ID No. 1801, Seq. ID No. 1803, Seq. ID No. 1805, Seq. ID No. 1811, Seq. ID No. 1817, Seq. ID No. 1819, Seq. ID No. 1821, Seq. ID No. 1825, Seq. ID No. 1829, Seq. ID No. 1837, Seq. ID No. 1843, Seq. ID No. 1845, Seq. ID No. 1847, Seq. ID No. 1849, Seq. ID No. 1851, Seq. ID No. 1855, Seq. ID No. 1859, Seq. ID No. 1863, Seq. ID No. 1865, Seq. ID No. 1867, Seq. ID No. 1871, Seq. ID No. 1873, Seq. ID No. 1877, Seq. ID No. 1885, Seq. ID No. 1887, Seq. ID No. 1889, Seq. ID No. 1895, Seq. ID No. 1897, Seq. ID No. 1899, Seq. ID No. 1903, Seq. ID No. 1905, Seq. ID No. 1913, Seq. ID No. 1919, Seq. ID No. 1923, Seq. ID No. 1925, Seq. ID No. 1931, Seq. ID No. 1935, Seq. ID No. 1937, Seq. ID No. 1943, Seq. ID No. 1945, Seq. ID No. 1949, Seq. ID No. 1953, Seq. ID No. 1957, Seq. ID No. 1959, Seq. ID No. 1961, Seq. ID No. 1965, Seq. ID No. 1967, Seq. ID No. 1971, Seq. ID No. 1975, Seq. ID No. 1979, Seq. ID No. 1983, Seq. ID No. 1987, Seq. ID No. 1989, Seq. ID No. 1991, Seq. ID No. 1999, Seq. ID No. 2001, Seq. ID No. 2003, Seq. ID No. 2009, Seq. ID No. 2015, Seq. ID No. 2019, Seq. ID No. 2021, Seq. ID No. 2031, Seq. 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ID No. 4867, Seq. ID No. 4875, Seq. ID No. 4877, Seq. ID No. 4879, Seq. ID No. 4881, Seq. ID No. 4883, Seq. ID No. 4885, Seq. ID No. 4887, Seq. ID No. 4893, Seq. ID No. 4899, Seq. ID No. 4901, Seq. ID No. 4903, Seq. ID No. 4905, Seq. ID No. 4907, Seq. ID No. 4911, Seq. ID No. 4915, Seq. ID No. 4917, Seq. ID No. 4919, Seq. ID No. 4921, Seq. ID No. 4927, Seq. ID No. 4931, Seq. ID No. 4935, Seq. ID No. 4939, Seq. ID No. 4941, Seq. ID No. 4943, Seq. ID No. 4945, Seq. ID No. 4947, Seq. ID No. 4953, Seq. ID No. 4957, Seq. ID No. 4959, Seq. ID No. 4963, Seq. ID No. 4965, Seq. ID No. 4969, Seq. ID No. 4971, Seq. ID No. 4973, Seq. ID No. 4979, Seq. ID No. 4985, Seq. ID No. 4989, Seq. ID No. 4991, Seq. ID No. 4995, Seq. ID No. 4997, Seq. ID No. 5001, Seq. ID No. 5007, Seq. ID No. 5009, Seq. ID No. 5017, Seq. ID No. 5021, Seq. ID No. 5027, Seq. ID No. 5029, Seq. ID No. 5039, Seq. ID No. 5047, Seq. ID No. 5051, Seq. ID No. 5053, Seq. ID No. 5055, Seq. ID No. 5059, Seq. ID No. 5061, Seq. ID No. 5069, Seq. ID No. 5077, Seq. ID No. 5079, Seq. ID No. 5081, Seq. ID No. 5083, Seq. ID No. 5087, Seq. ID No. 5091, Seq. ID No. 5093, Seq. ID No. 5097, Seq. ID No. 5103, Seq. ID No. 5105, Seq. ID No. 5109, Seq. ID No. 5111, Seq. ID No. 5113, Seq. ID No. 5115, Seq. ID No. 5117, Seq. ID No. 5127, Seq. ID No. 5141, Seq. ID No. 5145, Seq. ID No. 5149, Seq. ID No. 5153, Seq. ID No. 5157, Seq. ID No. 5165, Seq. ID No. 5169, Seq. ID No. 5171, Seq. ID No. 5177, Seq. ID No. 5183, Seq. ID No. 5185, Seq. ID No. 5187, Seq. ID No. 5193, Seq. ID No. 5195, Seq. ID No. 5201, Seq. ID No. 5203, Seq. ID No. 5205, Seq. ID No. 5209, Seq. ID No. 5211, Seq. ID No. 5215, Seq. ID No. 5219, Seq. ID No. 5227, Seq. ID No. 5231, Seq. ID No. 5235, Seq. ID No. 5237, Seq. ID No. 5239, Seq. ID No. 5243, Seq. ID No. 5245, Seq. ID No. 5247, Seq. ID No. 5253, Seq. ID No. 5255, Seq. ID No. 5257, Seq. ID No. 5261, Seq. ID No. 5263, Seq. ID No. 5271, Seq. ID No. 5275, Seq. ID No. 5283, Seq. ID No. 5291, Seq. ID No. 5299, Seq. ID No. 5305, Seq. ID No. 5309, Seq. ID No. 5311, Seq. ID No. 5313, Seq. ID No. 5319, Seq. ID No. 5323, Seq. ID No. 5325, Seq. ID No. 5335, Seq. ID No. 5337, Seq. ID No. 5341, Seq. ID No. 5345, Seq. ID No. 5351, Seq. ID No. 5355, Seq. ID No. 5363, Seq. ID No. 5365, Seq. ID No. 5367, Seq. ID No. 5371, Seq. ID No. 5373, Seq. ID No. 5381, Seq. ID No. 5383, Seq. ID No. 5387, Seq. ID No. 5389, Seq. ID No. 5391, Seq. ID No. 5393, Seq. ID No. 5395, Seq. ID No. 5397, Seq. ID No. 5399, Seq. ID No. 5401, Seq. ID No. 5403, Seq. ID No. 5409, Seq. ID No. 5411, Seq. ID No. 5415, Seq. ID No. 5417, Seq. ID No. 5419, Seq. ID No. 5421, Seq. ID No. 5423, Seq. ID No. 5427, Seq. ID No. 5431, Seq. ID No. 5433, Seq. ID No. 5439, Seq. ID No. 5441, Seq. ID No. 5443, Seq. ID No. 5447, Seq. ID No. 5449, Seq. ID No. 5451, Seq. ID No. 5453, Seq. ID No. 5455, Seq. ID No. 5457, Seq. ID No. 5473, Seq. ID No. 5477, Seq. ID No. 5483, Seq. ID No. 5487, Seq. ID No. 5491, Seq. ID No. 5495, Seq. ID No. 5499, Seq. ID No. 5503, Seq. ID No. 5507, Seq. ID No. 5509, Seq. ID No. 5513, Seq. ID No. 5527, Seq. ID No. 5531, Seq. ID No. 5537, Seq. ID No. 5539, Seq. ID No. 5541, Seq. ID No. 5547, Seq. ID No. 5553, Seq. ID No. 5557, Seq. ID No. 5559, Seq. ID No. 5563, Seq. ID No. 5567, Seq. ID No. 5571, Seq. ID No. 5575, Seq. ID No. 5581, Seq. ID No. 5585, Seq. ID No. 5591, Seq. ID No. 5599, Seq. ID No. 5601, Seq. ID No. 5605, Seq. ID No. 5615, Seq. ID No. 5621, Seq. ID No. 5629, Seq. ID No. 5631, Seq. ID No. 5637, Seq. ID No. 5647, Seq. ID No. 5651, Seq. ID No. 5655, Seq. ID No. 5657, Seq. ID No. 5661, Seq. ID No. 5665, Seq. ID No. 5669, Seq. ID No. 5671, Seq. ID No. 5673, Seq. ID No. 5679, Seq. ID No. 5685, Seq. ID No. 5693, Seq. ID No. 5697, Seq. ID No. 5699, Seq. ID No. 5701, Seq. ID No. 5707, Seq. ID No. 5715, Seq. ID No. 5717, Seq. ID No. 5723, Seq. ID No. 5727, Seq. ID No. 5735, Seq. ID No. 5739, Seq. ID No. 5749, Seq. ID No. 5751, Seq. ID No. 5755, Seq. ID No. 5761, Seq. ID No. 5771, Seq. ID No. 5775, Seq. ID No. 5777, Seq. ID No. 5779, Seq. ID No. 5783, Seq. ID No. 5789, Seq. ID No. 5795, Seq. ID No. 5801, Seq. ID No. 5803, Seq. ID No. 5809, Seq. ID No. 5815, Seq. ID No. 5819, Seq. ID No. 5825, Seq. ID No. 5833, Seq. ID No. 5835, Seq. ID No. 5841, Seq. ID No. 5845, Seq. ID No. 5847, Seq. ID No. 5849, Seq. ID No. 5851; Seq. ID No. 5853, Seq. ID No. 5855, Seq. ID No. 5859, Seq. ID No. 5865, Seq. ID No. 5871, Seq. ID No. 5875, Seq. ID No. 5877, Seq. ID No. 5881, Seq. ID No. 5887, Seq. ID No. 5891, Seq. ID No. 5895, Seq. ID No. 5897, Seq. ID No. 5901, Seq. ID No. 5903, Seq. ID No. 5911, Seq. ID No. 5913, Seq. ID No. 5915, Seq. ID No. 5917, Seq. ID No. 5919, Seq. ID No. 5929, Seq. ID No. 5931, Seq. ID No. 5933, Seq. ID No. 5937, Seq. ID No. 5941, Seq. ID No. 5943, Seq. ID No. 5947, Seq. ID No. 5951, Seq. ID No. 5953, Seq. ID No. 5955, Seq. ID No. 5957, Seq. ID No. 5961, Seq. ID No. 5969, Seq. ID No. 5973, Seq. ID No. 5979, Seq. ID No. 5981, Seq. ID No. 5985, Seq. ID No. 5989, Seq. ID No. 5993, Seq. ID No. 6001, Seq. ID No. 6003, Seq. ID No. 6011, Seq. ID No. 6015, Seq. ID No. 6017, Seq. ID No. 6021, Seq. ID No. 6027, Seq. ID No. 6029, Seq. ID No. 6033, Seq. ID No. 6035, Seq. ID No. 6041, Seq. ID No. 6043, Seq. ID No. 6053, Seq. ID No. 6057, Seq. ID No. 6065, Seq. ID No. 6071, Seq. ID No. 6079, Seq. ID No. 6085, Seq. ID No. 6089, Seq. ID No. 6095, Seq. ID No. 6097, Seq. ID No. 6101, Seq. ID No. 6103, Seq. ID No. 6111, Seq. ID No. 6113, Seq. ID No. 6117, Seq. ID No. 6123, Seq. ID No. 6125, Seq. ID No. 6129, Seq. ID No. 6131, Seq. ID No. 6133, Seq. ID No. 6141, Seq. ID No. 6145, Seq. ID No. 6149, Seq. ID No. 6157, Seq. ID No. 6165, Seq. ID No. 6169, Seq. ID No. 6171, Seq. ID No. 6175, Seq. ID No. 6177, Seq. ID No. 6181, Seq. ID No. 6187, Seq. ID No. 6195, Seq. ID No. 6201, Seq. ID No. 6209, Seq. ID No. 6213, Seq. ID No. 6215, Seq. ID No. 6219, Seq. ID No. 6233, Seq. ID No. 6235, Seq. ID No. 6243, Seq. ID No. 6249, Seq. ID No. 6251, Seq. ID No. 6257, Seq. ID No. 6261, Seq. ID No. 6263, Seq. ID No. 6271, Seq. ID No. 6275, Seq. ID No. 6277, Seq. ID No. 6281, Seq. ID No. 6287, Seq. ID No. 6297, Seq. ID No. 6299, Seq. ID No. 6305, Seq. ID No. 6311, Seq. ID No. 6315, Seq. ID No. 6321, Seq. ID No. 6323, Seq. ID No. 6327, Seq. ID No. 6331, Seq. ID No. 6333, Seq. ID No. 6337, Seq. ID No. 6339, Seq. ID No. 6341, Seq. ID No. 6343, Seq. ID No. 6345, Seq. ID No. 6353, Seq. ID No. 6357, Seq. ID No. 6359, Seq. ID No. 6361, Seq. ID No. 6367, Seq. ID No. 6369, Seq. ID No. 6373, Seq. ID No. 6375, Seq. ID No. 6377, Seq. ID No. 6379, Seq. ID No. 6389, Seq. ID No. 6395, Seq. ID No. 6399, Seq. ID No. 6403, Seq. ID No. 6407, Seq. ID No. 6411, Seq. ID No. 6413, Seq. ID No. 6417, Seq. ID No. 6423, Seq. ID No. 6433, Seq. ID No. 6437, Seq. ID No. 6439, Seq. ID No. 6445, Seq. ID No. 6449, Seq. ID No. 6451, Seq. ID No. 6457, Seq. ID No. 6459, Seq. ID No. 6461, Seq. ID No. 6463, Seq. ID No. 6477, Seq. ID No. 6481, Seq. ID No. 6483, Seq. ID No. 6487, Seq. ID No. 6489, Seq. ID No. 6491, Seq. ID No. 6493, Seq. ID No. 6495, Seq. ID No. 6503, Seq. ID No. 6505, Seq. ID No. 6511, Seq. ID No. 6515, Seq. ID No. 6519, Seq. ID No. 6523, Seq. ID No. 6525, Seq. ID No. 6529, Seq. ID No. 6531, Seq. ID No. 6533, Seq. ID No. 6537, Seq. ID No. 6545, Seq. ID No. 6551, Seq. ID No. 6553, Seq. ID No. 6559, Seq. ID No. 6563, Seq. ID No. 6567, Seq. ID No. 6577, Seq. ID No. 6579, Seq. ID No. 6583, Seq. ID No. 6585, Seq. ID No. 6587, Seq. ID No. 6589, Seq. ID No. 6603, Seq. ID No. 6605, Seq. ID No. 6609, Seq. ID No. 6613, Seq. ID No. 6615, Seq. ID No. 6617, Seq. ID No. 6621, Seq. ID No. 6623, Seq. ID No. 6627, Seq. ID No. 6629, Seq. ID No. 6633, and Seq. ID No.
 6639. 28. The polynucleotide of claim 7, wherein the polynucleotide encoded by the polynucleotide is identified by GeneMark™ ORF finder program, and the polynucleotide is selected from one of Seq. ID No. 1, Seq. ID No. 3, Seq. ID No. 11, Seq. ID No. 13, Seq. ID No. 15, Seq. ID No. 17, Seq. ID No. 25, Seq. ID No. 27, Seq. ID No. 29, Seq. ID No. 35, Seq. ID No. 37, Seq. ID No. 39, Seq. ID No. 41, Seq. ID No. 43, Seq. ID No. 45, Seq. ID No. 49, Seq. ID No. 53, Seq. ID No. 57, Seq. ID No. 61, Seq. ID No. 69, Seq. ID No. 71, Seq. ID No. 75, Seq. ID No. 81, Seq. ID No. 83, Seq. ID No. 89, Seq. ID No. 95, Seq. ID No. 101, Seq. ID No. 111, Seq. ID No. 119, Seq. ID No. 125, Seq. ID No. 129, Seq. ID No. 135, Seq. ID No. 137, Seq. ID No. 141, Seq. ID No. 147, Seq. ID No. 151, Seq. ID No. 155, Seq. ID No. 167, Seq. ID No. 171, Seq. ID No. 181, Seq. ID No. 185, Seq. ID No. 187, Seq. ID No. 189, Seq. ID No. 191, Seq. ID No. 195, Seq. ID No. 199, Seq. ID No. 207, Seq. ID No. 213, Seq. ID No. 219, Seq. ID No. 221, Seq. ID No. 225, Seq. ID No. 227, Seq. ID No. 229, Seq. ID No. 233, Seq. ID No. 239, Seq. ID No. 241, Seq. ID No. 243, Seq. ID No. 253, Seq. ID No. 261, Seq. ID No. 263, Seq. ID No. 267, Seq. ID No. 273, Seq. ID No. 275, Seq. ID No. 277, Seq. ID No. 279, Seq. ID No. 291, Seq. ID No. 293, Seq. ID No. 295, Seq. ID No. 299, Seq. ID No. 303, Seq. ID No. 309, Seq. ID No. 311, Seq. ID No. 315, Seq. ID No. 319, Seq. ID No. 323, Seq. ID No. 331, Seq. ID No. 341, Seq. ID No. 345, Seq. ID No. 351, Seq. ID No. 355, Seq. ID No. 361, Seq. ID No. 363, Seq. ID No. 365, Seq. ID No. 375, Seq. ID No. 379, Seq. ID No. 381, Seq. ID No. 383, Seq. ID No. 389, Seq. ID No. 391, Seq. ID No. 395, Seq. ID No. 399, Seq. ID No. 405, Seq. ID No. 409, Seq. ID No. 413, Seq. ID No. 417, Seq. ID No. 421, Seq. ID No. 423, Seq. ID No. 425, Seq. ID No. 427, Seq. ID No. 429, Seq. ID No. 435, Seq. ID No. 437, Seq. ID No. 439, Seq. ID No. 441, Seq. ID No. 443, Seq. ID No. 445, Seq. ID No. 447, Seq. ID No. 449, Seq. ID No. 459, Seq. ID No. 465, Seq. ID No. 485, Seq. ID No. 501, Seq. ID No. 505, Seq. ID No. 511, Seq. ID No. 513, Seq. ID No. 517, Seq. ID No. 519, Seq. ID No. 523, Seq. ID No. 529, Seq. ID No. 533, Seq. ID No. 535, Seq. ID No. 541, Seq. ID No. 543, Seq. ID No. 551, Seq. ID No. 553, Seq. ID No. 559, Seq. ID No. 563, Seq. ID No. 569, Seq. ID No. 575, Seq. ID No. 579, Seq. ID No. 583, Seq. ID No. 591, Seq. ID No. 595, Seq. ID No. 601, Seq. ID No. 605, Seq. ID No. 607, Seq. ID No. 611, Seq. ID No. 613, Seq. ID No. 615, Seq. ID No. 621, Seq. ID No. 627, Seq. ID No. 629, Seq. ID No. 633, Seq. ID No. 635, Seq. ID No. 637, Seq. ID No. 643, Seq. ID No. 649, Seq. ID No. 651, Seq. ID No. 655, Seq. ID No. 657, Seq. ID No. 669, Seq. ID No. 671, Seq. ID No. 675, Seq. ID No. 681, Seq. ID No. 683, Seq. ID No. 685, Seq. ID No. 693, Seq. ID No. 703, Seq. ID No. 705, Seq. ID No. 711, Seq. ID No. 725, Seq. ID No. 731, Seq. ID No. 735, Seq. ID No. 737, Seq. ID No. 741, Seq. ID No. 743, Seq. ID No. 749, Seq. ID No. 753, Seq. ID No. 759, Seq. ID No. 773, Seq. ID No. 781, Seq. ID No. 783, Seq. ID No. 785, Seq. ID No. 789, Seq. ID No. 793, Seq. ID No. 797, Seq. ID No. 803, Seq. ID No. 815, Seq. ID No. 819, Seq. ID No. 821, Seq. ID No. 827, Seq. ID No. 831, Seq. ID No. 833, Seq. ID No. 835, Seq. ID No. 837, Seq. ID No. 841, Seq. ID No. 843, Seq. ID No. 849, Seq. ID No. 851, Seq. ID No. 853, Seq. ID No. 857, Seq. ID No. 865, Seq. ID No. 869, Seq. ID No. 873, Seq. ID No. 877, Seq. ID No. 883, Seq. ID No. 887, Seq. ID No. 891, Seq. ID No. 895, Seq. ID No. 901, Seq. ID No. 907, Seq. ID No. 911, Seq. ID No. 917, Seq. ID No. 921, Seq. ID No. 927, Seq. ID No. 935, Seq. ID No. 939, Seq. ID No. 945, Seq. ID No. 951, Seq. ID No. 953, Seq. ID No. 959, Seq. ID No. 963, Seq. ID No. 967, Seq. ID No. 969, Seq. ID No. 977, Seq. ID No. 989, Seq. ID No. 995, Seq. ID No. 999, Seq. ID No. 1005, Seq. ID No. 1007, Seq. ID No. 1015, Seq. ID No. 1021, Seq. ID No. 1035, Seq. ID No. 1041, Seq. ID No. 1043, Seq. ID No. 1049, Seq. ID No. 1053, Seq. ID No. 1057, Seq. ID No. 1059, Seq. ID No. 1063, Seq. ID No. 1067, Seq. ID No. 1069, Seq. ID No. 1071, Seq. ID No. 1075, Seq. ID No. 1083, Seq. ID No. 1085, Seq. ID No. 1089, Seq. ID No. 1093, Seq. ID No. 1097, Seq. ID No. 1099, Seq. ID No. 1101, Seq. ID No. 1109, Seq. ID No. 1113, Seq. ID No. 1117, Seq. ID No. 1121, Seq. ID No. 1129, Seq. ID No. 1133, Seq. ID No. 1137, Seq. ID No. 1141, Seq. ID No. 1145, Seq. ID No. 1149, Seq. ID No. 1155, Seq. ID No. 1157, Seq. ID No. 1159, Seq. ID No. 1163, Seq. ID No. 1171, Seq. ID No. 1173, Seq. ID No. 1175, Seq. ID No. 1181, Seq. ID No. 1185, Seq. ID No. 1189, Seq. ID No. 1199, Seq. ID No. 1205, Seq. ID No. 1209, Seq. ID No. 1215, Seq. ID No. 1219, Seq. ID No. 1223, Seq. ID No. 1225, Seq. ID No. 1233, Seq. ID No. 1235, Seq. ID No. 1241, Seq. ID No. 1251, Seq. ID No. 1255, Seq. ID No. 1261, Seq. ID No. 1271, Seq. ID No. 1281, Seq. ID No. 1315, Seq. ID No. 1323, Seq. ID No. 1331, Seq. ID No. 1333, Seq. ID No. 1339, Seq. ID No. 1345, Seq. ID No. 1347, Seq. ID No. 1355, Seq. ID No. 1357, Seq. ID No. 1369, Seq. ID No. 1373, Seq. ID No. 1387, Seq. ID No. 1391, Seq. ID No. 1395, Seq. ID No. 1397, Seq. ID No. 1403, Seq. ID No. 1405, Seq. ID No. 1407, Seq. ID No. 1413, Seq. ID No. 1415, Seq. ID No. 1417, Seq. ID No. 1425, Seq. ID No. 1427, Seq. ID No. 1429, Seq. ID No. 1431, Seq. ID No. 1433, Seq. ID No. 1435, Seq. ID No. 1439, Seq. ID No. 1441, Seq. ID No. 1451, Seq. ID No. 1453, Seq. ID No. 1459, Seq. ID No. 1461, Seq. ID No. 1469, Seq. ID No. 1471, Seq. ID No. 1473, Seq. ID No. 1475, Seq. ID No. 1477, Seq. ID No. 1483, Seq. ID No. 1487, Seq. ID No. 1489, Seq. ID No. 1493, Seq. ID No. 1495, Seq. ID No. 1497, Seq. ID No. 1501, Seq. ID No. 1503, Seq. ID No. 1507, Seq. ID No. 1509, Seq. ID No. 1517, Seq. ID No. 1521, Seq. ID No. 1527, Seq. ID No. 1531, Seq. ID No. 1537, Seq. ID No. 1541, Seq. ID No. 1543, Seq. ID No. 1549, Seq. ID No. 1561, Seq. ID No. 1563, Seq. ID No. 1565, Seq. ID No. 1569, Seq. ID No. 1573, Seq. ID No. 1575, Seq. ID No. 1581, Seq. ID No. 1587, Seq. ID No. 1591, Seq. ID No. 1595, Seq. ID No. 1597, Seq. ID No. 1605, Seq. ID No. 1609, Seq. ID No. 1613, Seq. ID No. 1619, Seq. ID No. 1623, Seq. ID No. 1627, Seq. ID No. 1629, Seq. ID No. 1635, Seq. ID No. 1641, Seq. ID No. 1647, Seq. ID No. 1651, Seq. ID No. 1657, Seq. ID No. 1659, Seq. ID No. 1667, Seq. ID No. 1669, Seq. ID No. 1679, Seq. ID No. 1683, Seq. ID No. 1687, Seq. ID No. 1691, Seq. ID No. 1697, Seq. ID No. 1699, Seq. ID No. 1701, Seq. ID No. 1707, Seq. ID No. 1709, Seq. ID No. 1713, Seq. ID No. 1717, Seq. ID No. 1721, Seq. ID No. 1725, Seq. ID No. 1735, Seq. ID No. 1737, Seq. ID No. 1739, Seq. ID No. 1743, Seq. ID No. 1745, Seq. ID No. 1749, Seq. ID No. 1755, Seq. ID No. 1769, Seq. ID No. 1773, Seq. ID No. 1777, Seq. ID No. 1785, Seq. ID No. 1789, Seq. ID No. 1791, Seq. ID No. 1797, Seq. ID No. 1799, Seq. ID No. 1803, Seq. ID No. 1805, Seq. ID No. 1807, Seq. ID No. 1817, Seq. ID No. 1819, Seq. ID No. 1821, Seq. ID No. 1825, Seq. ID No. 1827, Seq. ID No. 1831, Seq. ID No. 1835, Seq. ID No. 1841, Seq. ID No. 1845, Seq. ID No. 1847, Seq. ID No. 1849, Seq. ID No. 1851, Seq. ID No. 1855, Seq. ID No. 1859, Seq. ID No. 1861, Seq. ID No. 1865, Seq. ID No. 1867, Seq. ID No. 1871, Seq. ID No. 1873, Seq. ID No. 1877, Seq. ID No. 1879, Seq. ID No. 1887, Seq. ID No. 1889, Seq. ID No. 1895, Seq. ID No. 1897, Seq. ID No. 1899, Seq. ID No. 1901, Seq. ID No. 1905, Seq. ID No. 1909, Seq. ID No. 1917, Seq. ID No. 1921, Seq. ID No. 1925, Seq. ID No. 1931, Seq. ID No. 1933, Seq. ID No. 1937, Seq. ID No. 1939, Seq. ID No. 1945, Seq. ID No. 1947, Seq. ID No. 1951, Seq. ID No. 1955, Seq. ID No. 1959, Seq. ID No. 1961, Seq. ID No. 1965, Seq. ID No. 1967, Seq. ID No. 1969, Seq. ID No. 1973, Seq. ID No. 1977, Seq. ID No. 1979, Seq. ID No. 1983, Seq. ID No. 1989, Seq. ID No. 1991, Seq. ID No. 1997, Seq. ID No. 2001, Seq. 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ID No. 4875, Seq. ID No. 4879, Seq. ID No. 4881, Seq. ID No. 4883, Seq. ID No. 4885, Seq. ID No. 4887, Seq. ID No. 4893, Seq. ID No. 4899, Seq. ID No. 4901, Seq. ID No. 4903, Seq. ID No. 4905, Seq. ID No. 4907, Seq. ID No. 4909, Seq. ID No. 4915, Seq. ID No. 4917, Seq. ID No. 4919, Seq. ID No. 4921, Seq. ID No. 4925, Seq. ID No. 4929, Seq. ID No. 4933, Seq. ID No. 4937, Seq. ID No. 4941, Seq. ID No. 4943, Seq. ID No. 4945, Seq. ID No. 4947, Seq. ID No. 4953, Seq. ID No. 4955, Seq. ID No. 4959, Seq. ID No. 4961, Seq. ID No. 4965, Seq. ID No. 4967, Seq. ID No. 4971, Seq. ID No. 4973, Seq. ID No. 4977, Seq. ID No. 4985, Seq. ID No. 4989, Seq. ID No. 4991, Seq. ID No. 4995, Seq. ID No. 4997, Seq. ID No. 5005, Seq. ID No. 5009, Seq. ID No. 5015, Seq. ID No. 5019, Seq. ID No. 5025, Seq. ID No. 5029, Seq. ID No. 5037, Seq. ID No. 5045, Seq. ID No. 5049, Seq. ID No. 5053, Seq. ID No. 5055, Seq. ID No. 5059, Seq. ID No. 5061, Seq. ID No. 5065, Seq. ID No. 5071, Seq. ID No. 5073, Seq. ID No. 5079, Seq. ID No. 5081, Seq. ID No. 5083, Seq. ID No. 5087, Seq. ID No. 5089, Seq. ID No. 5093, Seq. ID No. 5095, Seq. ID No. 5103, Seq. ID No. 5105, Seq. ID No. 5107, Seq. ID No. 5111, Seq. ID No. 5113, Seq. ID No. 5115, Seq. ID No. 5117, Seq. ID No. 5119, Seq. ID No. 5141, Seq. ID No. 5143, Seq. ID No. 5147, Seq. ID No. 5153, Seq. ID No. 5155, Seq. ID No. 5163, Seq. ID No. 5169, Seq. ID No. 5171, Seq. ID No. 5173, Seq. ID No. 5179, Seq. ID-No. 5185, Seq. ID No. 5187, Seq. ID No. 5193, Seq. ID No. 5195, Seq. ID No. 5201, Seq. ID No. 5203, Seq. ID No. 5205, Seq. ID No. 5209, Seq. ID No. 5211, Seq. ID No. 5213, Seq. ID No. 5217, Seq. ID No. 5225, Seq. ID No. 5231, Seq. ID No. 5233, Seq. ID No. 5237, Seq. ID No. 5239, Seq. ID No. 5245, Seq. ID No. 5247, Seq. ID No. 5249, Seq. ID No. 5255, Seq. ID No. 5257, Seq. ID No. 5259, Seq. ID No. 5263, Seq. ID No. 5269, Seq. ID No. 5273, Seq. ID No. 5283, Seq. ID No. 5289, Seq. ID No. 5293, Seq. ID No. 5307, Seq. ID No. 5311, Seq. ID No. 5313, Seq. ID No. 5315, Seq. ID No. 5323, Seq. ID No. 5325, Seq. ID No. 5335, Seq. ID No. 5337, Seq. ID No. 5339, Seq. ID No. 5345, Seq. ID No. 5347, Seq. ID No. 5349, Seq. ID No. 5353, Seq. ID No. 5361, Seq. ID No. 5365, Seq. ID No. 5367, Seq. ID No. 5369, Seq. ID No. 5373, Seq. ID No. 5375, Seq. ID No. 5387, Seq. ID No. 5389, Seq. ID No. 5391, Seq. ID No. 5393, Seq. ID No. 5395, Seq. ID No. 5397, Seq. ID No. 5399, Seq. ID No. 5401, Seq. ID No. 5403, Seq. ID No. 5405, Seq. ID No. 5411, Seq. ID No. 5415, Seq. ID No. 5417, Seq. ID No. 5419, Seq. ID No. 5421, Seq. ID No. 5423, Seq. ID No. 5429, Seq. ID No. 5433, Seq. ID No. 5441, Seq. ID No. 5443, Seq. ID No. 5445, Seq. ID No. 5449, Seq. ID No. 5451, Seq. ID No. 5453, Seq. ID No. 5455, Seq. ID No. 5457, Seq. ID No. 5469, Seq. ID No. 5475, Seq. ID No. 5483, Seq. ID No. 5485, Seq. ID No. 5489, Seq. ID No. 5493, Seq. ID No. 5499, Seq. ID No. 5501, Seq. ID No. 5505, Seq. ID No. 5509, Seq. ID No. 5511, Seq. ID No. 5523, Seq. ID No. 5529, Seq. ID No. 5535, Seq. ID No. 5539, Seq. ID No. 5541, Seq. ID No. 5547, Seq. ID No. 5551, Seq. ID No. 5555, Seq. ID No. 5559, Seq. ID No. 5561, Seq. ID No. 5565, Seq. ID No. 5571, Seq. ID No. 5573, Seq. ID No. 5579, Seq. ID No. 5583, Seq. ID No. 5589, Seq. ID No. 5599, Seq. ID No. 5601, Seq. ID No. 5603, Seq. ID No. 5613, Seq. ID No. 5621, Seq. ID No. 5627, Seq. ID No. 5631, Seq. ID No. 5635, Seq. ID No. 5645, Seq. ID No. 5651, Seq. ID No. 5653, Seq. ID No. 5657, Seq. ID No. 5661, Seq. ID No. 5663, Seq. ID No. 5665, Seq. ID No. 5669, Seq. ID No. 5671, Seq. ID No. 5673, Seq. ID No. 5675, Seq. ID No. 5681, Seq. ID No. 5693, Seq. ID No. 5695, Seq. ID No. 5699, Seq. ID No. 5701, Seq. ID No. 5707, Seq. ID No. 5713, Seq. ID No. 5717, Seq. ID No. 5723, Seq. ID No. 5725, Seq. ID No. 5731, Seq. ID No. 5737, Seq. ID No. 5747, Seq. ID No. 5751, Seq. ID No. 5755, Seq. ID No. 5759, Seq. ID No. 5771, Seq. ID No. 5773, Seq. ID No. 5777, Seq. ID No. 5779, Seq. ID No. 5781, Seq. ID No. 5785, Seq. ID No. 5793, Seq. ID No. 5799, Seq. ID No. 5805, Seq. ID No. 5811, Seq. ID No. 5815, Seq. ID No. 5817, Seq. ID No. 5823, Seq. ID No. 5831, Seq. ID No. 5835, Seq. ID No. 5839, Seq. ID No. 5843, Seq. ID No. 5847, Seq. ID No. 5849, Seq. ID No. 5851, Seq. ID No. 5853, Seq. ID No. 5855, Seq. ID No. 5857, Seq. ID No. 5861, Seq. ID No. 5867, Seq. ID No. 5875, Seq. ID No. 5877, Seq. ID No. 5881, Seq. ID No. 5889, Seq. ID No. 5895, Seq. ID No. 5897, Seq. ID No. 5901, Seq. ID No. 5903, Seq. ID No. 5907, Seq. ID No. 5913, Seq. ID No. 5915, Seq. ID No. 5917, Seq. ID No. 5919, Seq. ID No. 5925, Seq. ID No. 5931, Seq. ID No. 5933, Seq. ID No. 5935, Seq. ID No. 5941, Seq. ID No. 5943, Seq. ID No. 5945, Seq. ID No. 5949, Seq. ID No. 5955, Seq. ID No. 5957, Seq. ID No. 5959, Seq. ID No. 5967, Seq. ID No. 5971, Seq. ID No. 5975, Seq. ID No. 5977, Seq. ID No. 5981, Seq. ID No. 5983, Seq. ID No. 5985, Seq. ID No. 5989, Seq. ID No. 5991, Seq. ID No. 5995, Seq. ID No. 5997, Seq. ID No. 6003, Seq. ID No. 6005, Seq. ID No. 6007, Seq. ID No. 6015, Seq. ID No. 6017, Seq. ID No. 6019, Seq. ID No. 6023, Seq. ID No. 6029, Seq. ID No. 6033, Seq. ID No. 6035, Seq. ID No. 6037, Seq. ID No. 6043, Seq. ID No. 6049, Seq. ID No. 6055, Seq. ID No. 6065, Seq. ID No. 6069, Seq. ID No. 6075, Seq. ID No. 6081, Seq. ID No. 6083, Seq. ID No. 6087, Seq. ID No. 6095, Seq. ID No. 6097, Seq. ID No. 6099, Seq. ID No. 6103, Seq. ID No. 6105, Seq. ID No. 6113, Seq. ID No. 6115, Seq. ID No. 6119, Seq. ID No. 6125, Seq. ID No. 6127, Seq. ID No. 6129, Seq. ID No. 6131, Seq. ID No. 6133, Seq. ID No. 6141, Seq. ID No. 6143, Seq. ID No. 6147, Seq. ID No. 6153, Seq. ID No. 6165, Seq. ID No. 6169, Seq. ID No. 6171, Seq. ID No. 6173, Seq. ID No. 6177, Seq. ID No. 6179, Seq. ID No. 6187, Seq. ID No. 6193, Seq. ID No. 6201, Seq. ID No. 6207, Seq. ID No. 6211, Seq. ID No. 6215, Seq. ID No. 6219, Seq. ID No. 6231, Seq. ID No. 6235, Seq. ID No. 6243, Seq. ID No. 6247, Seq. ID No. 6251, Seq. ID No. 6255, Seq. ID No. 6261, Seq. ID No. 6263, Seq. ID No. 6269, Seq. ID No. 6275, Seq. ID No. 6277, Seq. ID No. 6279, Seq. ID No. 6287, Seq. ID No. 6291, Seq. ID No. 6299, Seq. ID No. 6305, Seq. ID No. 6307, Seq. ID No. 6313, Seq. ID No. 6315, Seq. ID No. 6321, Seq. ID No. 6323, Seq. ID No. 6325, Seq. ID No. 6331, Seq. ID No. 6335, Seq. ID No. 6339, Seq. ID No. 6341, Seq. ID No. 6343, Seq. ID No. 6345, Seq. ID No. 6347, Seq. ID No. 6355, Seq. ID No. 6359, Seq. ID No. 6361, Seq. ID No. 6365, Seq. ID No. 6369, Seq. ID No. 6371, Seq. ID No. 6375, Seq. ID No. 6377, Seq. ID No. 6379, Seq. ID No. 6387, Seq. ID No. 6391, Seq. ID No. 6397, Seq. ID No. 6401, Seq. ID No. 6405, Seq. ID No. 6409, Seq. ID No. 6413, Seq. ID No. 6417, Seq. ID No. 6419, Seq. ID No. 6423, Seq. ID No. 6429, Seq. ID No. 6433, Seq. ID No. 6435, Seq. ID No. 6439, Seq. ID No. 6445, Seq. ID No. 6447, Seq. ID No. 6451, Seq. ID No. 6455, Seq. ID No. 6459, Seq. ID No. 6461, Seq. ID No. 6463, Seq. ID No. 6475, Seq. ID No. 6481, Seq. ID No. 6483, Seq. ID No. 6485, Seq. ID No. 6487, Seq. ID No. 6489, Seq. ID No. 6491, Seq. ID No. 6493, Seq. ID No. 6495, Seq. ID No. 6499, Seq. ID No. 6505, Seq. ID No. 6509, Seq. ID No. 6513, Seq. ID No. 6519, Seq. ID No. 6521, Seq. ID No. 6525, Seq. ID No. 6527, Seq. ID No. 6531, Seq. ID No. 6533, Seq. ID No. 6535, Seq. ID No. 6545, Seq. ID No. 6551, Seq. ID No. 6553, Seq. ID No. 6559, Seq. ID No. 6561, Seq. ID No. 6563, Seq. ID No. 6565, Seq. ID No. 6567, Seq. ID No. 6569, Seq. ID No. 6575, Seq. ID No. 6579, Seq. ID No. 6583, Seq. ID No. 6585, Seq. ID No. 6591, Seq. ID No. 6595, Seq. ID No. 6605, Seq. ID No. 6607, Seq. ID No. 6611, Seq. ID No. 6615, Seq. ID No. 6617, Seq. ID No. 6619, Seq. ID No. 6623, Seq. ID No. 6625, Seq. ID No. 6629, Seq. ID No. 6633, Seq. ID No. 6635, Seq. ID No. 6641, and Seq. ID No.
 6647. 29. The polynucleotide of claim 7, wherein the polynucleotide that encodes a polypeptide is identified using an ORF finder program that searches for an ATG, GTG or TTG Start codon between a Stop-Stop region, and the polynucleotide is selected from one of Seq. ID No. 1, Seq. ID No. 5, Seq. ID No. 11, Seq. ID No. 13, Seq. ID No. 15, Seq. ID No. 17, Seq. ID No. 19, Seq. ID No. 21, Seq. ID No. 23, Seq. ID No. 27, Seq. ID No. 29, Seq. ID No. 31, Seq. ID No. 35, Seq. ID No. 37, Seq. ID No. 41, Seq. ID No. 43, Seq. ID No. 45, Seq. ID No. 47, Seq. ID No. 49, Seq. ID No. 51, Seq. ID No. 53, Seq. ID No. 55, Seq. ID No. 57, Seq. ID No. 59, Seq. ID No. 65, Seq. ID No. 67, Seq. ID No. 75, Seq. ID No. 77, Seq. ID No. 79, Seq. ID No. 81, Seq. ID No. 83, Seq. ID No. 89, Seq. ID No. 91, Seq. ID No. 93, Seq. ID No. 97, Seq. ID No. 99, Seq. ID No. 103, Seq. ID No. 105, Seq. ID No. 107, Seq. ID No. 109, Seq. ID No. 111, Seq. ID No. 113, Seq. ID No. 115, Seq. ID No. 117, Seq. ID No. 119, Seq. ID No. 121, Seq. ID No. 127, Seq. ID No. 129, Seq. ID No. 131, Seq. ID No. 133, Seq. ID No. 135, Seq. ID No. 137, Seq. ID No. 139, Seq. ID No. 143, Seq. ID No. 145, Seq. ID No. 147, Seq. ID No. 149, Seq. ID No. 153, Seq. ID No. 155, Seq. ID No. 157, Seq. ID No. 159, Seq. ID No. 161, Seq. ID No. 163, Seq. ID No. 165, Seq. ID No. 167, Seq. ID No. 169, Seq. ID No. 171, Seq. ID No. 175, Seq. ID No. 177, Seq. ID No. 179, Seq. ID No. 181, Seq. ID No. 183, Seq. ID No. 187, Seq. ID No. 191, Seq. ID No. 193, Seq. ID No. 195, Seq. ID No. 201, Seq. ID No. 205, Seq. ID No. 207, Seq. ID No. 215, Seq. ID No. 219, Seq. ID No. 221, Seq. ID No. 223, Seq. ID No. 225, Seq. ID No. 227, Seq. ID No. 231, Seq. ID No. 233, Seq. ID No. 239, Seq. ID No. 243, Seq. ID No. 245, Seq. ID No. 247, Seq. ID No. 253, Seq. ID No. 257, Seq. ID No. 259, Seq. ID No. 261, Seq. ID No. 263, Seq. ID No. 265, Seq. ID No. 267, Seq. ID No. 269, Seq. ID No. 273, Seq. ID No. 277, Seq. ID No. 279, Seq. ID No. 281, Seq. ID No. 283, Seq. ID No. 291, Seq. ID No. 293, Seq. ID No. 297, Seq. ID No. 301, Seq. ID No. 305, Seq. ID No. 307, Seq. ID No. 309, Seq. ID No. 313, Seq. ID No. 317, Seq. ID No. 321, Seq. ID No. 323, Seq. ID No. 325, Seq. ID No. 331, Seq. ID No. 333, Seq. ID No. 335, Seq. ID No. 337, Seq. ID No. 339, Seq. ID No. 343, Seq. ID No. 345, Seq. ID No. 347, Seq. ID No. 349, Seq. ID No. 353, Seq. ID No. 355, Seq. ID No. 357, Seq. ID No. 359, Seq. ID No. 361, Seq. ID No. 363, Seq. ID No. 365, Seq. ID No. 367, Seq. ID No. 369, Seq. ID No. 371, Seq. ID No. 375, Seq. ID No. 377, Seq. ID No. 379, Seq. ID No. 383, Seq. ID No. 385, Seq. ID No. 387, Seq. ID No. 389, Seq. ID No. 391, Seq. ID No. 393, Seq. ID No. 397, Seq. ID No. 401, Seq. ID No. 403, Seq. ID No. 405, Seq. ID No. 407, Seq. ID No. 409, Seq. ID No. 415, Seq. ID No. 423, Seq. ID No. 425, Seq. ID No. 427, Seq. ID No. 429, Seq. ID No. 431, Seq. ID No. 433, Seq. ID No. 435, Seq. ID No. 437, Seq. ID No. 439, Seq. ID No. 441, Seq. ID No. 443, Seq. ID No. 445, Seq. ID No. 447, Seq. ID No. 451, Seq. ID No. 453, Seq. ID No. 455, Seq. ID No. 457, Seq. ID No. 461, Seq. ID No. 463, Seq. ID No. 467, Seq. ID No. 469, Seq. ID No. 471, Seq. ID No. 473, Seq. ID No. 475, Seq. ID No. 477, Seq. ID No. 479, Seq. ID No. 481, Seq. ID No. 483, Seq. ID No. 485, Seq. ID No. 489, Seq. ID No. 491, Seq. ID No. 493, Seq. ID No. 495, Seq. ID No. 501, Seq. ID No. 505, Seq. ID No. 507, Seq. ID No. 511, Seq. ID No. 515, Seq. ID No. 517, Seq. ID No. 523, Seq. ID No. 529, Seq. ID No. 531, Seq. ID No. 533, Seq. ID No. 537, Seq. ID No. 539, Seq. ID No. 543, Seq. ID No. 547, Seq. ID No. 549, Seq. ID No. 551, Seq. ID No. 553, Seq. ID No. 555, Seq. ID No. 557, Seq. ID No. 559, Seq. ID No. 561, Seq. ID No. 565, Seq. ID No. 569, Seq. ID No. 571, Seq. ID No. 573, Seq. ID No. 575, Seq. ID No. 579, Seq. ID No. 581, Seq. ID No. 585, Seq. ID No. 587, Seq. ID No. 589, Seq. ID No. 591, Seq. ID No. 593, Seq. ID No. 595, Seq. ID No. 597, Seq. ID No. 599, Seq. ID No. 601, Seq. ID No. 603, Seq. ID No. 605, Seq. ID No. 609, Seq. ID No. 613, Seq. ID No. 615, Seq. ID No. 617, Seq. ID No. 619, Seq. ID No. 621, Seq. ID No. 623, Seq. ID No. 625, Seq. ID No. 627, Seq. ID No. 635, Seq. ID No. 637, Seq. ID No. 643, Seq. ID No. 645, Seq. ID No. 647, Seq. ID No. 649, Seq. ID No. 655, Seq. ID No. 663, Seq. ID No. 665, Seq. ID No. 667, Seq. ID No. 669, Seq. ID No. 675, Seq. ID No. 681, Seq. ID No. 683, Seq. ID No. 687, Seq. ID No. 689, Seq. ID No. 691, Seq. ID No. 695, Seq. ID No. 697, Seq. ID No. 699, Seq. ID No. 701, Seq. ID No. 703, Seq. ID No. 705, Seq. ID No. 707, Seq. ID No. 709, Seq. ID No. 713, Seq. ID No. 725, Seq. ID No. 727, Seq. ID No. 729, Seq. ID No. 731, Seq. ID No. 733, Seq. ID No. 735, Seq. ID No. 739, Seq. ID No. 741, Seq. ID No. 745, Seq. ID No. 747, Seq. ID No. 749, Seq. ID No. 751, Seq. ID No. 753, Seq. ID No. 759, Seq. ID No. 763, Seq. ID No. 765, Seq. ID No. 773, Seq. ID No. 775, Seq. ID No. 781, Seq. ID No. 783, Seq. ID No. 787, Seq. ID No. 793, Seq. ID No. 795, Seq. ID No. 799, Seq. ID No. 801, Seq. ID No. 805, Seq. ID No. 807, Seq. ID No. 809, Seq. ID No. 811, Seq. ID No. 813, Seq. ID No. 815, Seq. ID No. 817, Seq. ID No. 819, Seq. ID No. 821, Seq. ID No. 823, Seq. ID No. 827, Seq. ID No. 829, Seq. ID No. 831, Seq. ID No. 835, Seq. ID No. 837, Seq. ID No. 839, Seq. ID No. 843, Seq. ID No. 845, Seq. ID No. 847, Seq. ID No. 855, Seq. ID No. 859, Seq. ID No. 861, Seq. ID No. 865, Seq. ID No. 867, Seq:ID No. 871, Seq. ID No. 873, Seq. ID No. 875, Seq. ID No. 877, Seq. ID No. 879, Seq. ID No. 881, Seq. ID No. 885, Seq. ID No. 895, Seq. ID No. 897, Seq. ID No. 899, Seq. ID No. 901, Seq. ID No. 903, Seq. ID No. 905, Seq. ID No. 907, Seq. ID No. 909, Seq. ID No. 913, Seq. ID No. 915, Seq. ID No. 921, Seq. ID No. 923, Seq. ID No. 925, Seq. ID No. 931, Seq. ID No. 933, Seq. ID No. 935, Seq. ID No. 937, Seq. ID No. 939, Seq. ID No. 941, Seq. ID No. 943, Seq. ID No. 947, Seq. ID No. 949, Seq. ID No. 951, Seq. ID No. 953, Seq. ID No. 955, Seq. ID No. 957, Seq. ID No. 961, Seq. ID No. 963, Seq. ID No. 965, Seq. ID No. 967, Seq. ID No. 969, Seq. ID No. 971, Seq. ID No. 973, Seq. ID No. 975, Seq. ID No. 981, Seq. ID No. 983, Seq. ID No. 985, Seq. ID No. 987, Seq. ID No. 989, Seq. ID No. 991, Seq. ID No. 993, Seq. ID No. 995, Seq. ID No. 997, Seq. ID No. 1001, Seq. ID No. 1003, Seq. ID No. 1005, Seq. ID No. 1007, Seq. ID No. 1009, Seq. ID No. 1017, Seq. ID No. 1019, Seq. ID No. 1023, Seq. ID No. 1025, Seq. ID No. 1027, Seq. ID No. 1039, Seq. ID No. 1041, Seq. ID No. 1043, Seq. ID No. 1045, Seq. ID No. 1047, Seq. ID No. 1049, Seq. ID No. 1051, Seq. ID No. 1057, Seq. ID No. 1059, Seq. ID No. 1061, Seq. ID No. 1065, Seq. ID No. 1069, Seq. ID No. 1075, Seq. ID No. 1077, Seq. ID No. 1079, Seq. ID No. 1081, Seq. ID No. 1083, Seq. ID No. 1085, Seq. ID No. 1087, Seq. ID No. 1091, Seq. ID No. 1093, Seq. ID No. 1095, Seq. ID No. 1097, Seq. ID No. 1099, Seq. ID No. 1101, Seq. ID No. 1103, Seq. ID No. 1107, Seq. ID No. 1109, Seq. ID No. 1111, Seq. ID No. 1113, Seq. ID No. 1115, Seq. ID No. 1119, Seq. ID No. 1121, Seq. ID No. 1123, Seq. ID No. 1125, Seq. ID No. 1127, Seq. ID No. 1129, Seq. ID No. 1131, Seq. ID No. 1137, Seq. ID No. 1139, Seq. ID No. 1141, Seq. ID No. 1143, Seq. ID No. 1145, Seq. ID No. 1147, Seq. ID No. 1149, Seq. ID No. 1151, Seq. ID No. 1153, Seq. ID No. 1155, Seq. ID No. 1157, Seq. ID No. 1159, Seq. ID No. 1161, Seq. ID No. 1163, Seq. ID No. 1171, Seq. ID No. 1175, Seq. ID No. 1177, Seq. ID No. 1179, Seq. ID No. 1181, Seq. ID No. 1187, Seq. ID No. 1191, Seq. ID No. 1193, Seq. ID No. 1195, Seq. ID No. 1197, Seq. ID No. 1201, Seq. ID No. 1203, Seq. ID No. 1205, Seq. ID No. 1207, Seq. ID No. 1211, Seq. ID No. 1213, Seq. ID No. 1215, Seq. ID No. 1217, Seq. ID No. 1221, Seq. ID No. 1223, Seq. ID No. 1225, Seq. ID No. 1231, Seq. ID No. 1233, Seq. ID No. 1237, Seq. ID No. 1239, Seq. ID No. 1241, Seq. ID No. 1245, Seq. 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ID No. 2021, Seq. ID No. 2025, Seq. ID No. 2027, Seq. ID No. 2029, Seq. ID No. 2031, Seq. ID No. 2035, Seq. ID No. 2037, Seq. ID No. 2041, Seq. ID No. 2043, Seq. ID No. 2045, Seq. ID No. 2047, Seq. ID No. 2053, Seq. ID No. 2055, Seq. ID No. 2059, Seq. ID No. 2063, Seq. ID No. 2065, Seq. ID No. 2067, Seq. ID No. 2069, Seq. ID No. 2071, Seq. ID No. 2073, Seq. ID No. 2075, Seq. ID No. 2077, Seq. ID No. 2079, Seq. ID No. 2081, Seq. ID No. 2083, Seq. ID No. 2085, Seq. ID No. 2089, Seq. ID No. 2091, Seq. ID No. 2093, Seq. ID No. 2097, Seq. ID No. 2099, Seq. ID No. 2101, Seq. ID No. 2103, Seq. ID No. 2107, Seq. ID No. 2109, Seq. ID No. 2111, Seq. ID No. 2115, Seq. ID No. 2117, Seq. ID No. 2119, Seq. ID No. 2125, Seq. ID No. 2127, Seq. ID No. 2129, Seq. ID No. 2131, Seq. ID No. 2133, Seq. ID No. 2135, Seq. ID No. 2137, Seq. ID No. 2141, Seq. ID No. 2143, Seq. ID No. 2145, Seq. ID No. 2149, Seq. ID No. 2151, Seq. ID No. 2153, Seq. ID No. 2155, Seq. ID No. 2157, Seq. ID No. 2159, Seq. 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ID No. 2351, Seq. ID No. 2357, Seq. ID No. 2363, Seq. ID No. 2365, Seq. ID No. 2367, Seq. ID No. 2369, Seq. ID No. 2371, Seq. ID No. 2373, Seq. ID No. 2375, Seq. ID No. 2379, Seq. ID No. 2381, Seq. ID No. 2385, Seq. ID No. 2387, Seq. ID No. 2391, Seq. ID No. 2393, Seq. ID No. 2395, Seq. ID No. 2397, Seq. ID No. 2399, Seq. ID No. 2401, Seq. ID No. 2405, Seq. ID No. 2409, Seq. ID No. 2413, Seq. ID No. 2415, Seq. ID No. 2417, Seq. ID No. 2421, Seq. ID No. 2423, Seq. ID No. 2425, Seq. ID No. 2427, Seq. ID No. 2429, Seq. ID No. 2435, Seq. ID No. 2437, Seq. ID No. 2445, Seq. ID No. 2447, Seq. ID No. 2449, Seq. ID No. 2451, Seq. ID No. 2453, Seq. ID No. 2455, Seq. ID No. 2457, Seq. ID No. 2459, Seq. ID No. 2461, Seq. ID No. 2463, Seq. ID No. 2465, Seq. ID No. 2469, Seq. ID No. 2471, Seq. ID No. 2475, Seq. ID No. 2481, Seq. ID No. 2483, Seq. ID No. 2485, Seq. ID No. 2491, Seq. ID No. 2493, Seq. ID No. 2495, Seq. ID No. 2499, Seq. ID No. 2501, Seq. ID No. 2503, Seq. ID No. 2505, Seq. ID No. 2507, Seq. ID No. 2511, Seq. ID No. 2513, Seq. ID No. 2517, Seq. ID No. 2519, Seq. ID No. 2521, Seq. ID No. 2525, Seq. ID No. 2529, Seq. ID No. 2533, Seq. ID No. 2535, Seq. ID No. 2537, Seq. ID No. 2539, Seq. ID No. 2547, Seq. ID No. 2549, Seq. ID No. 2551, Seq. ID No. 2553, Seq. ID No. 2559, Seq. ID No. 2561, Seq. ID No. 2563, Seq. ID No. 2565, Seq. ID No. 2573, Seq. ID No. 2575, Seq. ID No. 2577, Seq. ID No. 2579, Seq. ID No. 2581, Seq. ID No. 2587, Seq. ID No. 2589, Seq. ID No. 2591, Seq. ID No. 2593, Seq. ID No. 2595, Seq. ID No. 2599, Seq. ID No. 2603, Seq. ID No. 2605, Seq. ID No. 2607, Seq. ID No. 2609, Seq. ID No. 2611, Seq. ID No. 2613, Seq. ID No. 2617, Seq. ID No. 2619, Seq. ID No. 2623, Seq. ID No. 2625, Seq. ID No. 2627, Seq. ID No. 2629, Seq. ID No. 2631, Seq. ID No. 2633, Seq. ID No. 2635, Seq. ID No. 2637, Seq. ID No. 2639, Seq. ID No. 2641, Seq. ID No. 2643, Seq. ID No. 2645, Seq. ID No. 2647, Seq. ID No. 2649, Seq. ID No. 2651, Seq. ID No. 2653, Seq. ID No. 2655, Seq. ID No. 2659, Seq. ID No. 2663, Seq. ID No. 2667, Seq. ID No. 2669, Seq. ID No. 2671, Seq. ID No. 2675, Seq. ID No. 2677, Seq. ID No. 2683, Seq. ID No. 2685, Seq. ID No. 2687, Seq. ID No. 2689, Seq. ID No. 2691, Seq. ID No. 2693, Seq. ID No. 2695, Seq. ID No. 2697, Seq. ID No. 2699, Seq. ID No. 2703, Seq. ID No. 2709, Seq. ID No. 2711, Seq. ID No. 2715, Seq. ID No. 2717, Seq. ID No. 2719, Seq. ID No. 2723, Seq. ID No. 2725, Seq. ID No. 2727, Seq. ID No. 2729, Seq. ID No. 2731, Seq. ID No. 2735, Seq. ID No. 2737, Seq. ID No. 2739, Seq. ID No. 2749, Seq. ID No. 2751, Seq. ID No. 2753, Seq. ID No. 2755, Seq. ID No. 2759, Seq. ID No. 2765, Seq. ID No. 2767, Seq. ID No. 2769, Seq. ID No. 2771, Seq. ID No. 2773, Seq. ID No. 2775, Seq. ID No. 2779, Seq. ID No. 2781, Seq. ID No. 2783, Seq. ID No. 2787, Seq. ID No. 2789, Seq. ID No. 2791, Seq. ID No. 2793, Seq. ID No. 2795, Seq. ID No. 2797, Seq. ID No. 2799, Seq. ID No. 2801, Seq. ID No. 2803, Seq. ID No. 2807, Seq. ID No. 2809, Seq. ID No. 2813, Seq. ID No. 2815, Seq. ID No. 2821, Seq. ID No. 2823, Seq. ID No. 2827, Seq. ID No. 2829, Seq. ID No. 2831, Seq. ID No. 2833, Seq. ID No. 2839, Seq. ID No. 2841, Seq. ID No. 2843, Seq. ID No. 2845, Seq. ID No. 2847, Seq. ID No. 2855, Seq. ID No. 2861, Seq. ID No. 2863, Seq. ID No. 2865, Seq. ID No. 2867, Seq. ID No. 2869, Seq. ID No. 2871, Seq. ID No. 2877, Seq. ID No. 2881, Seq. ID No. 2883, Seq. ID No. 2885, Seq. ID No. 2887, Seq. ID No. 2891, Seq. ID No. 2893, Seq. ID No. 2895, Seq. ID No. 2899, Seq. ID No. 2901, Seq. ID No. 2907, Seq. ID No. 2915, Seq. ID No. 2917, Seq. ID No. 2919, Seq. ID No. 2921, Seq. ID No. 2923, Seq. ID No. 2927, Seq. ID No. 2931, Seq. ID No. 2933, Seq. ID No. 2935, Seq. ID No. 2943, Seq. ID No. 2945, Seq. ID No. 2951, Seq. ID No. 2953, Seq. ID No. 2957, Seq. ID No. 2959, Seq. ID No. 2961, Seq. ID No. 2963, Seq. ID No. 2965, Seq. ID No. 2967, Seq. ID No. 2971, Seq. ID No. 2973, Seq. ID No. 2975, Seq. ID No. 2977, Seq. ID No. 2979, Seq. ID No. 2983, Seq. ID No. 2985, Seq. ID No. 2987, Seq. ID No. 2991, Seq. ID No. 2993, Seq. ID No. 2999, Seq. ID No. 3001, Seq. ID No. 3005, Seq. ID No. 3009, Seq. ID No. 3011, Seq. ID No. 3015, Seq. ID No. 3017, Seq. ID No. 3019, Seq. ID No. 3021, Seq. ID No. 3027, Seq. ID No. 3033, Seq. ID No. 3035, Seq. ID No. 3037, Seq. ID No. 3039, Seq. ID No. 3043, Seq. ID No. 3045, Seq. ID No. 3047, Seq. ID No. 3049, Seq. ID No. 3051, Seq. ID No. 3053, Seq. ID No. 3055, Seq. ID No. 3057, Seq. ID No. 3059, Seq. ID No. 3067, Seq. ID No. 3069, Seq. ID No. 3071, Seq. ID No. 3079, Seq. ID No. 3083, Seq. ID No. 3085, Seq. ID No. 3087, Seq. ID No. 3091, Seq. ID No. 3093, Seq. ID No. 3099, Seq. ID No. 3101, Seq. ID No. 3103, Seq. ID No. 3109, Seq. ID No. 3111, Seq. ID No. 3115, Seq. ID No. 3117, Seq. ID No. 3119, Seq. ID No. 3121, Seq. ID No. 3123, Seq. ID No. 3125, Seq. ID No. 3129, Seq. ID No. 3131, Seq. ID No. 3133, Seq. ID No. 3135, Seq. ID No. 3137, Seq. ID No. 3139, Seq. 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ID No. 5279, Seq. ID No. 5281, Seq. ID No. 5285, Seq. ID No. 5287, Seq. ID No. 5291, Seq. ID No. 5295, Seq. ID No. 5297, Seq. ID No. 5299, Seq. ID No. 5301, Seq. ID No. 5303, Seq. ID No. 5305, Seq. ID No. 5307, Seq. ID No. 5309, Seq. ID No. 5311, Seq. ID No. 5313, Seq. ID No. 5317, Seq. ID No. 5319, Seq. ID No. 5321, Seq. ID No. 5323, Seq. ID No. 5327, Seq. ID No. 5329, Seq. ID No. 5331, Seq. ID No. 5333, Seq. ID No. 5335, Seq. ID No. 5337, Seq. ID No. 5343, Seq. ID No. 5345, Seq. ID No. 5349, Seq. ID No. 5351, Seq. ID No. 5357, Seq. ID No. 5359, Seq. ID No. 5365, Seq. ID No. 5367, Seq. ID No. 5373, Seq. ID No. 5377, Seq. ID No. 5379, Seq. ID No. 5381, Seq. ID No. 5383, Seq. ID No. 5387, Seq. ID No. 5389, Seq. ID No. 5391, Seq. ID No. 5393, Seq. ID No. 5397, Seq. ID No. 5399, Seq. ID No. 5401, Seq. ID No. 5403, Seq. ID No. 5405, Seq. ID No. 5407, Seq. ID No. 5409, Seq. ID No. 5411, Seq. ID No. 5415, Seq. ID No. 5417, Seq. ID No. 5419, Seq. ID No. 5421, Seq. ID No. 5423, Seq. ID No. 5425, Seq. ID No. 5427, Seq. ID No. 5431, Seq. ID No. 5433, Seq. ID No. 5435, Seq. ID No. 5437, Seq. ID No. 5439, Seq. ID No. 5441, Seq. ID No. 5443, Seq. ID No. 5447, Seq. ID No. 5449, Seq. ID No. 5451, Seq. ID No. 5453, Seq. ID No. 5455, Seq. ID No. 5457, Seq. ID No. 5467, Seq. ID No. 5471, Seq. ID No. 5473, Seq. ID No. 5477, Seq. ID No. 5479, Seq: ID No. 5481, Seq. ID No. 5491, Seq. ID No. 5493, Seq. ID No. 5495, Seq. ID No. 5499, Seq. ID No. 5503, Seq. ID No. 5509, Seq. ID No. 5513, Seq. ID No. 5515, Seq. ID No. 5517, Seq. ID No. 5519, Seq. ID No. 5521, Seq. ID No. 5527, Seq. ID No. 5529, Seq. ID No. 5531, Seq. ID No. 5533, Seq. ID No. 5537, Seq. ID No. 5539, Seq. ID No. 5541, Seq. ID No. 5543, Seq. ID No. 5545, Seq. ID No. 5547, Seq. ID No. 5549, Seq. ID No. 5551, Seq. ID No. 5553, Seq. ID No. 5557, Seq. ID No. 5559, Seq. ID No. 5563, Seq. ID No. 5567, Seq. ID No. 5569, Seq. ID No. 5575, Seq. ID No. 5577, Seq. ID No. 5581, Seq. ID No. 5583, Seq. ID No. 5585, Seq. ID No. 5589, Seq. ID No. 5591, Seq. ID No. 5593, Seq. ID No. 5595, Seq. ID No. 5599, Seq. ID No. 5601, Seq. ID No. 5607, Seq. ID No. 5613, Seq. ID No. 5615, Seq. ID No. 5617, Seq. ID No. 5619, Seq. ID No. 5621, Seq. ID No. 5625, Seq. ID No. 5627, Seq. ID No. 5629, Seq. ID No. 5631, Seq. ID No. 5637, Seq. ID No. 5639, Seq. ID No. 5641, Seq. ID No. 5645, Seq. ID No. 5647, Seq. ID No. 5649, Seq. ID No. 5651, Seq. ID No. 5655 Seq. ID No. 5657, Seq. ID No. 5661, Seq. ID No. 5665, Seq. ID No. 5667, Seq. ID No. 5669, Seq. ID No. 5677, Seq. ID No. 5679, Seq. ID No. 5683, Seq. ID No. 5685, Seq. ID No. 5687, Seq. ID No. 5689, Seq. ID No. 5691, Seq. ID No. 5693, Seq. ID No. 5697, Seq. ID No. 5699, Seq. ID No. 5701, Seq. ID No. 5703, Seq. ID No. 5705, Seq. ID No. 5707, Seq. ID No. 5711, Seq. ID No. 5713, Seq. ID No. 5715, Seq. ID No. 5717, Seq. ID No. 5719, Seq. ID No. 5721, Seq. ID No. 5723, Seq. ID No. 5725, Seq. ID No. 5727, Seq. ID No. 5735, Seq. ID No. 5739, Seq. ID No. 5741, Seq. ID No. 5743, Seq. ID No. 5745, Seq. ID No. 5747, Seq. ID No. 5749, Seq. ID No. 5751, Seq. ID No. 5753, Seq. ID No. 5755, Seq. ID No. 5757, Seq. ID No. 5759, Seq. ID No. 5761, Seq. ID No. 5769, Seq. ID No. 5771, Seq. ID No. 5777, Seq. ID No. 5779, Seq. ID No. 5783, Seq. ID No. 5787, Seq. ID No. 5791, Seq. ID No. 5795, Seq. ID No. 5799, Seq. ID No. 5801, Seq. ID No. 5807, Seq. ID No. 5809, Seq. ID No. 5813, Seq. ID No. 5815, Seq. ID No. 5819, Seq. ID No. 5821, Seq. ID No. 5823, Seq. ID No. 5825, Seq. ID No. 5827, Seq. ID No. 5829, Seq. ID No. 5831, Seq. ID No. 5833, Seq. ID No. 5835, Seq. ID No. 5837, Seq. ID No. 5839, Seq. ID No. 5841, Seq. ID No. 5845, Seq. ID No. 5847, Seq. ID No. 5849, Seq. ID No. 5851, Seq. ID No. 5855, Seq. ID No. 5857, Seq. ID No. 5859, Seq. ID No. 5861, Seq. ID No. 5863, Seq. ID No. 5865, Seq. ID No. 5869, Seq. ID No. 5871, Seq. ID No. 5873, Seq. ID No. 5875, Seq. ID No. 5879, Seq. ID No. 5881, Seq. ID No. 5883, Seq. ID No. 5889, Seq. ID No. 5895, Seq. ID No. 5897, Seq. ID No. 5901, Seq. ID No. 5903, Seq. ID No. 5911, Seq. ID No. 5913, Seq. ID No. 5915, Seq. ID No. 5917, Seq. ID No. 5919, Seq. ID No. 5927, Seq. ID No. 5929, Seq. ID No. 5933, Seq. ID No. 5935, Seq. ID No. 5937, Seq. ID No. 5941, Seq. ID No. 5945, Seq. ID No. 5947, Seq. ID No. 5951, Seq. ID No. 5959, Seq. ID No. 5961, Seq. ID No. 5963, Seq. ID No. 5965, Seq. ID No. 5967, Seq. ID No. 5969, Seq. ID No. 5971, Seq. ID No. 5973, Seq. ID No. 5977, Seq. ID No. 5979, Seq. ID No. 5981, Seq. ID No. 5985, Seq. ID No. 5987, Seq. ID No. 5989, Seq. ID No. 5991, Seq. ID No. 5993, Seq. ID No. 5995, Seq. ID No. 5999, Seq. ID No. 6001, Seq. ID No. 6003, Seq. ID No. 6009, Seq. ID No. 6011, Seq. ID No. 6013, Seq. ID No. 6015, Seq. ID No. 6017, Seq. ID No. 6025, Seq. ID No. 6027, Seq. ID No. 6029, Seq. ID No. 6031, Seq. ID No. 6033, Seq. ID No. 6035, Seq. ID No. 6039, Seq. ID No. 6041, Seq. ID No. 6043, Seq. ID No. 6045, Seq. ID No. 6049, Seq. ID No. 6051, Seq. ID No. 6053, Seq. ID No. 6055, Seq. ID No. 6057, Seq. ID No. 6061, Seq. ID No. 6063, Seq. ID No. 6065, Seq. ID No. 6069, Seq. ID No. 6071, Seq. ID No. 6073, Seq. ID No. 6077, Seq. ID No. 6079, Seq. ID No. 6085, Seq. ID No. 6087, Seq. ID No. 6089, Seq. ID No. 6093, Seq. ID No. 6095, Seq. ID No. 6101, Seq. ID No. 6103, Seq. ID No. 6109, Seq. ID No. 6111, Seq. ID No. 6117, Seq. ID No. 6121, Seq. ID No. 6123, Seq. ID No. 6129, Seq. ID No. 6131, Seq. ID No. 6133, Seq. ID No. 6135, Seq. ID No. 6137, Seq. ID No. 6139, Seq. ID No. 6141, Seq. ID No. 6145, Seq. ID No. 6151, Seq. ID No. 6155, Seq. ID No. 6157, Seq. ID No. 6159, Seq. ID No. 6165, Seq. ID No. 6167, Seq. ID No. 6169, Seq. ID No. 6171, Seq. ID No. 6175, Seq. ID No. 6177, Seq. ID No. 6181, Seq. ID No. 6187, Seq. ID No. 6193, Seq. ID No. 6195, Seq. ID No. 6197, Seq. ID No. 6199, Seq. ID No. 6201, Seq. ID No. 6209, Seq. ID No. 6213, Seq. ID No. 6215, Seq. ID No. 6217, Seq. ID No. 6219, Seq. ID No. 6231, Seq. ID No. 6233, Seq. ID No. 6235, Seq. ID No. 6239, Seq. ID No. 6241, Seq. ID No. 6243, Seq. ID No. 6249, Seq. ID No. 6257, Seq. ID No. 6259, Seq. ID No. 6261, Seq. ID No. 6263, Seq. ID No. 6267, Seq. ID No. 6269, Seq. ID No. 6271, Seq. ID No. 6275, Seq. ID No. 6277, Seq. ID No. 6279, Seq. ID No. 6281, Seq. ID No. 6283, Seq. ID No. 6285, Seq. ID No. 6287, Seq. ID No. 6293, Seq. ID No. 6295, Seq. ID No. 6297, Seq. ID No. 6299, Seq. ID No. 6305, Seq. ID No. 6309, Seq. ID No. 6311, Seq. ID No. 6315, Seq. ID No. 6317, Seq. ID No. 6319, Seq. ID No. 6321, Seq. ID No. 6323, Seq. ID No. 6325, Seq. ID No. 6327, Seq. ID No. 6329, Seq. ID No. 6331, Seq. ID No. 6335, Seq. ID No. 6337, Seq. ID No. 6341, Seq. ID No. 6345, Seq. ID No. 6349, Seq. ID No. 6351, Seq. ID No. 6353, Seq. ID No. 6359, Seq. ID No. 6361, Seq. ID No. 6367, Seq. ID No; 6369, Seq. ID No. 6371, Seq. ID No. 6373, Seq. ID No. 6375, Seq. ID No. 6377, Seq. ID No. 6379, Seq. ID No. 6381, Seq. ID No. 6385, Seq. ID No. 6389, Seq. ID No. 6393, Seq. ID No. 6395, Seq. ID No. 6399, Seq. ID No. 6409, Seq. ID No. 6411, Seq. ID No. 6413, Seq. ID No. 6417, Seq. ID No. 6421, Seq. ID No. 6423, Seq. ID No. 6425, Seq. ID No. 6427, Seq. ID No. 6429, Seq. ID No. 6431, Seq. ID No. 6441, Seq. ID No. 6443, Seq. ID No. 6445, Seq. ID No. 6451, Seq. ID No. 6453, Seq. ID No. 6459, Seq. ID No. 6461, Seq. ID No. 6463, Seq. ID No. 6465, Seq. ID No. 6467, Seq. ID No. 6469, Seq. ID No. 6471, Seq. ID No. 6473, Seq. ID No. 6479, Seq. ID No. 6483, Seq. ID No. 6493, Seq. ID No. 6495, Seq. ID No. 6497, Seq. ID No. 6501, Seq. ID No. 6503, Seq. ID No. 6505, Seq. ID No. 6507, Seq. ID No. 6511, Seq. ID No. 6517, Seq. ID No. 6523, Seq. ID No. 6525, Seq. ID No. 6535, Seq. ID No. 6537, Seq. ID No. 6539, Seq. ID No. 6541, Seq. ID No. 6543, Seq. ID No. 6545, Seq. ID No. 6547, Seq. ID No. 6549, Seq. ID No. 6551, Seq. ID No. 6553, Seq. ID No. 6555, Seq. ID No. 6557, Seq. ID No. 6559, Seq. ID No. 6563, Seq. ID No. 6573, Seq. ID No. 6575, Seq. ID No. 6577, Seq. ID No. 6579, Seq. ID No. 6583, Seq. ID No. 6585, Seq. ID No. 6587, Seq. ID No. 6591, Seq. ID No. 6597, Seq. ID No. 6601, Seq. ID No. 6603, Seq. ID No. 6605, Seq. ID No. 6609, Seq. ID No. 6611, Seq. ID No. 6613, Seq. ID No. 6615, Seq. ID No. 6617, Seq. ID No. 6619, Seq. ID No. 6621, Seq. ID No. 6623, Seq. ID No. 6627, Seq. ID No. 6629, Seq. ID No. 6631, Seq. ID No. 6633, Seq. ID No. 6637, Seq. ID No. 6639, Seq. ID No. 6643, Seq. ID No. 6645, and Seq. ID No.
 6649. 30. The polynucleotide of claim 7 wherein the polynucleotide encodes a polypeptide that is identified by an ORF finder program, which searches for a transmembrane domain between two Stop codons and a Start codon immediately upstream of this transmembrane region, and the polynucleotide is selected from one of Seq. ID No. 7, Seq. ID No. 9, Seq. ID No. 33, Seq. ID No. 47, Seq. ID No. 67, Seq. ID No. 85, Seq. ID No. 87, Seq. ID No. 123, Seq. ID No. 133, Seq. ID No. 141, Seq. ID No. 159, Seq. ID No. 163, Seq. ID No. 191, Seq. ID No. 209, Seq. ID No. 211, Seq. ID No. 215, Seq. ID No. 217, Seq. ID No. 225, Seq. ID No. 235, Seq. ID No. 237, Seq. ID No. 249, Seq. ID No. 251, Seq. ID No. 255, Seq. ID No. 271, Seq. ID No. 277., Seq. ID No. 285, Seq. ID No. 287, Seq. ID No. 289, Seq. ID No. 327, Seq. ID No. 329, Seq. ID No. 373, Seq. ID No. 375, Seq. ID No. 419, Seq. ID No. 487, Seq. ID No. 497, Seq. ID No. 499, Seq. ID No. 503, Seq. ID No. 505, Seq. ID No. 509, Seq. ID No. 511, Seq. ID No. 515, Seq. ID No. 525, Seq. ID No. 527, Seq. ID No. 545, Seq. ID No. 567, Seq. ID No. 569, Seq. ID No. 575, Seq. ID No. 577, Seq. ID No. 579, Seq. ID No. 593, Seq. ID No. 617, Seq. ID No. 637, Seq. ID No. 639, Seq. ID No. 641, Seq. ID No. 645, Seq. ID No. 653, Seq. ID No. 655, Seq. ID No. 659, Seq. ID No. 669, Seq. ID No. 675, Seq. ID No. 677, Seq. ID No. 679, Seq. ID No. 715, Seq. ID No. 717, Seq. ID No. 719, Seq. ID No. 721, Seq. ID No. 723, Seq. ID No. 747, Seq. ID No. 751, Seq. ID No. 755, Seq. ID No. 757, Seq. ID No. 759, Seq. ID No. 761, Seq. ID No. 763, Seq. ID No. 769, Seq. ID No. 777, Seq. ID No. 779, Seq. ID No. 807, Seq. ID No. 809, Seq. ID No. 819, Seq. ID No. 825, Seq. ID No. 863, Seq. ID No. 893, Seq. ID No. 901, Seq. ID No. 935, Seq. ID No. 943, Seq. ID No. 955, Seq. ID No. 967, Seq. ID No. 979, Seq. ID No. 1005, Seq. ID No. 1009, Seq. ID No. 1011, Seq. ID No. 1013, Seq. ID No. 1015, Seq. ID No. 1019, Seq. ID No. 1029, Seq. ID No. 1031, Seq. ID No. 1033, Seq. ID No. 1037, Seq. ID No. 1039, Seq. ID No. 1045, Seq. ID No. 1055, Seq. ID No. 1075, Seq. ID No. 1105, Seq. ID No. 1131, Seq. ID No. 1135, Seq. ID No. 1137, Seq. ID No. 1165, Seq. ID No. 1167, Seq. ID No. 1169, Seq. ID No. 1183, Seq. ID No. 1193, Seq. ID No. 1197, Seq. ID No. 1213, Seq. ID No. 1223, Seq. ID No. 1227, Seq. ID No. 1229, Seq. ID No. 1237, Seq. ID No. 1243, Seq. ID No. 1265, Seq. ID No. 1267, Seq. ID No. 1269, Seq. ID No. 1271, Seq. ID No. 1283, Seq. ID No. 1287, Seq. ID No. 1291, Seq. ID No. 1297, Seq. ID No. 1305, Seq. ID No. 1315, Seq. ID No. 1325, Seq. ID No. 1327, Seq. ID No. 1329, Seq. ID No. 1331, Seq. ID No. 1341, Seq. ID No. 1353, Seq. ID No. 1367, Seq. ID No. 1401, Seq. ID No. 1429, Seq. ID No. 1435, Seq. ID No. 1445, Seq. ID No. 1481, Seq. ID No. 1513, Seq. ID No. 1515, Seq. ID No. 1517, Seq. ID No. 1529, Seq. ID No. 1533, Seq. ID No. 1535, Seq. ID No. 1545, Seq. ID No. 1547, Seq. ID No. 1551, Seq. ID No. 1559, Seq. ID No. 1563, Seq. ID No. 1571, Seq. ID No. 1579, Seq. ID No. 1583, Seq. ID No. 1585, Seq. ID No. 1621, Seq. ID No. 1633, Seq. ID No. 1643, Seq. ID No. 1645, Seq. ID No. 1647, Seq. ID No. 1649, Seq. ID No. 1653, Seq. ID No. 1671, Seq. ID No. 1673, Seq. ID No. 1677, Seq. ID No. 1681, Seq. ID No. 1707, Seq. ID No. 1731, Seq. ID No. 1733, Seq. ID No. 1737, Seq. ID No. 1753, Seq. ID No. 1757, Seq. ID No. 1765, Seq. ID No. 1767, Seq. ID No. 1787, Seq. ID No. 1791, Seq. ID No. 1797, Seq. ID No. 1805, Seq. ID No. 1819, Seq. ID No. 1821, Seq. ID No. 1823, Seq. ID No. 1839, Seq. ID No. 1869, Seq. ID No. 1875, Seq. ID No. 1891, Seq. ID No. 1893, Seq. ID No. 1895, Seq. ID No. 1923, Seq. ID No. 1927, Seq. ID No. 1969, Seq. ID No. 1981, Seq. ID No. 1991, Seq. ID No. 1993, Seq. ID No. 2013, Seq. ID No. 2017, Seq. ID No. 2027, Seq. ID No. 2033, Seq. ID No. 2041, Seq. ID No. 2049, Seq. ID No. 2053, Seq. ID No. 2087, Seq. ID No. 2089, Seq. ID No. 2105, Seq. ID No. 2115, Seq. ID No. 2121, Seq. ID No. 2127, Seq. ID No. 2151, Seq. ID No. 2159, Seq. ID No. 2171, Seq. ID No. 2173, Seq. ID No. 2177, Seq. ID No. 2187, Seq. ID No. 2237, Seq. ID No. 2239, Seq. ID No. 2245, Seq. ID No. 2249, Seq. ID No. 2271, Seq. ID No. 2283, Seq. ID No. 2289, Seq. ID No. 2291, Seq. ID No. 2293, Seq. ID No. 2295, Seq. ID No. 2303, Seq. ID No. 2305, Seq. ID No. 2307, Seq. ID No. 2317, Seq. ID No. 2319, Seq. ID No. 2321, Seq. ID No. 2323, Seq. ID No. 2325, Seq. ID No. 2327, Seq. ID No. 2333, Seq. ID No. 2343, Seq. ID No. 2347, Seq. ID No. 2349, Seq. ID No. 2351, Seq. ID No. 2353, Seq. ID No. 2355, Seq. ID No. 2357, Seq. ID No. 2365, Seq. ID No. 2389, Seq. ID No. 2391, Seq. ID No. 2407, Seq. ID No. 2419, Seq. ID No. 2421, Seq. ID No. 2427, Seq. ID No. 2429, Seq. ID No. 2433, Seq. ID No. 2449, Seq. ID No. 2459, Seq. ID No. 2489, Seq. ID No. 2497, Seq. ID No. 2503, Seq. ID No. 2507, Seq. ID No. 2515, Seq. ID No. 2523, Seq. ID No. 2525, Seq. ID No. 2531, Seq. ID No. 2535, Seq. ID No. 2537, Seq. ID No. 2541, Seq. ID No. 2543, Seq. ID No. 2545, Seq. ID No. 2555, Seq. ID No. 2557, Seq. ID No. 2569, Seq. ID No. 2571, Seq. ID No. 2583, Seq. ID No. 2591, Seq. ID No. 2597, Seq. ID No. 2599, Seq. ID No. 2601, Seq. ID No. 2607, Seq. ID No. 2611, Seq. ID No. 2621, Seq. ID No. 2629, Seq. ID No. 2651, Seq. ID No. 2679, Seq. ID No. 2693, Seq. ID No. 2701, Seq. ID No. 2703, Seq. ID No. 2705, Seq. ID No. 2707, Seq. ID No. 2731, Seq. ID No. 2733, Seq. ID No. 2783, Seq. ID No. 2785, Seq. ID No. 2813, Seq. ID No. 2815, Seq. ID No. 2823, Seq. ID No. 2835, Seq. ID No. 2837, Seq. ID No. 2841, Seq. ID No. 2853, Seq. ID No. 2873, Seq. ID No. 2875, Seq. ID No. 2881, Seq. ID No. 2905, Seq. ID No. 2935, Seq. ID No. 2937, Seq. ID No. 2939, Seq. ID No. 2941, Seq. ID No. 2947, Seq. ID No. 2949, Seq. ID No. 2969, Seq. ID No. 2973, Seq. ID No. 2977, Seq. ID No. 2981, Seq. ID No. 2987, Seq. ID No. 2991, Seq. ID No. 2995, Seq. ID No. 2997, Seq. ID No. 3005, Seq. ID No. 3007, Seq. ID No. 3013, Seq. ID No. 3023, Seq. ID No. 3025, Seq. ID No. 3027, Seq. ID No. 3029, Seq. ID No. 3031, Seq. ID No. 3043, Seq. ID No. 3055, Seq. ID No. 3063, Seq. ID No. 3071, Seq. ID No. 3073, Seq. ID No. 3075, Seq. ID No. 3077, Seq. ID No. 3123, Seq. ID No. 3145, Seq. ID No. 3155, Seq. ID No. 3157, Seq. ID No. 3163, Seq. ID No. 3183, Seq. ID No. 3193, Seq. ID No. 3201, Seq. ID No. 3213, Seq. ID No. 3215, Seq. ID No. 3217, Seq. ID No. 3219, Seq. ID No. 3241, Seq. ID No. 3243, Seq. ID No. 3245, Seq. ID No. 3249, Seq. ID No. 3257, Seq. ID No. 3261, Seq. ID No. 3269, Seq. ID No. 3275, Seq. ID No. 3297, Seq. ID No. 3317, Seq. ID No. 3323, Seq. ID No. 3337, Seq. ID No. 3339, Seq. ID No. 3349, Seq. ID No. 3351, Seq. ID No. 3353, Seq. ID No. 3357, Seq. ID No. 3359, Seq. ID No. 3377, Seq. ID No. 3389, Seq. ID No. 3391, Seq. ID No. 3395, Seq. ID No. 3405, Seq. ID No. 3421, Seq. ID No. 3425, Seq. ID No. 3449, Seq. ID No. 3451, Seq. ID No. 3453, Seq. ID No. 3455, Seq. ID No. 3457, Seq. ID No. 3463, Seq. ID No. 3481, Seq. ID No. 3491, Seq. ID No. 3493, Seq. ID No. 3503, Seq. ID No. 3505, Seq. ID No. 3527, Seq. ID No. 3593, Seq. ID No. 3595, Seq. ID No. 3621, Seq. ID No. 3625, Seq. ID No. 3635, Seq. ID No. 3679, Seq. ID No. 3723, Seq. ID No. 3727, Seq. ID No. 3745, Seq. ID No. 3753, Seq. ID No. 3755, Seq. ID No. 3757, Seq. ID No. 3761, Seq. ID No. 3763, Seq. ID No. 3765, Seq. ID No. 3783, Seq. ID No. 3793, Seq. ID No. 3799, Seq. ID No. 3813, Seq. ID No. 3837, Seq. ID No. 3839, Seq. ID No. 3849, Seq. ID No. 3851, Seq. ID No. 3853, Seq. ID No. 3859, Seq. ID No. 3861, Seq. ID No. 3863, Seq. ID No. 3865, Seq. ID No. 3879, Seq. ID No. 3889, Seq. ID No. 3891, Seq. ID No. 3903, Seq. ID No. 3925, Seq. ID No. 3963, Seq. ID No. 3973, Seq. ID No. 3975, Seq. ID No. 4005, Seq. ID No. 4025, Seq. ID No. 4027, Seq. ID No. 4039, Seq. ID No. 4041, Seq. ID No. 4043, Seq. ID No. 4045, Seq. ID No. 4047, Seq. ID No. 4061, Seq. ID No. 4071, Seq. ID No. 4073, Seq. ID No. 4079, Seq. ID No. 4081, Seq. ID No. 4083, Seq. ID No. 4101, Seq. ID No. 4103, Seq. ID No. 4111, Seq. ID No. 4133, Seq. ID No. 4137, Seq. ID No. 4139, Seq. ID No. 4145, Seq. ID No. 4151, Seq. ID No. 4221, Seq. ID No. 4223, Seq. ID No. 4225, Seq. ID No. 4227, Seq. ID No. 4231, Seq. ID No. 4241, Seq. ID No. 4247, Seq. ID No. 4253, Seq. ID No. 4257, Seq. ID No. 4261, Seq. ID No. 4307, Seq. ID No. 4311, Seq. ID No. 4313, Seq. ID No. 4343, Seq. ID No. 4379, Seq. ID No. 4385, Seq. ID No. 4389, Seq. ID No. 4439, Seq. ID No. 4469, Seq. ID No. 4473, Seq. ID No. 4481, Seq. ID No. 4483, Seq. ID No. 4485, Seq. ID No. 4497, Seq. ID No. 4515, Seq. ID No. 4533, Seq. ID No. 4587, Seq. ID No. 4639, Seq. ID No. 4643, Seq. ID No. 4681, Seq. ID No. 4705, Seq. ID No. 4707, Seq. ID No. 4709, Seq. ID No. 4711, Seq. ID No. 4715, Seq. ID No. 4717, Seq. ID No. 4737, Seq. ID No. 4759, Seq. ID No. 4813, Seq. ID No. 4827, Seq. ID No. 4869, Seq. ID No. 4871, Seq. ID No. 4873, Seq. ID No. 4875, Seq. ID No. 4919, Seq. ID No. 4931, Seq. ID No. 4949, Seq. ID No. 4951, Seq. ID No. 4987, Seq. ID No. 5031, Seq. ID No. 5061, Seq. ID No. 5085, Seq. ID No. 5103, Seq. ID No. 5123, Seq. ID No. 5129, Seq. ID No. 5131, Seq. ID No. 5135, Seq. ID No. 5137, Seq. ID No. 5141, Seq. ID No. 5165, Seq. ID No. 5175, Seq. ID No. 5199, Seq. ID No. 5205, Seq. ID No. 5207, Seq. ID No. 5213, Seq. ID No. 5219, Seq. ID No. 5223, Seq. ID No. 5267, Seq. ID No. 5281, Seq. ID No. 5385, Seq. ID No. 5387, Seq. ID No. 5413, Seq. ID No. 5415, Seq. ID No. 5433, Seq. ID No. 5453, Seq. ID No. 5459, Seq. ID No. 5461, Seq. ID No. 5463, Seq. ID No. 5465, Seq. ID No. 5491, Seq. ID No. 5497, Seq. ID No. 5509, Seq. ID No. 5513, Seq. ID No. 5525, Seq. ID No. 5531, Seq. ID No. 5569, Seq. ID No. 5587, Seq. ID No. 5595, Seq. ID No. 5597, Seq. ID No. 5609, Seq. ID No. 5611, Seq. ID No. 5621, Seq. ID No. 5623, Seq. ID No. 5633, Seq. ID No. 5637, Seq. ID No. 5643, Seq. ID No. 5649, Seq. ID No. 5659, Seq. ID No. 5683, Seq. ID No. 5685, Seq. ID No. 5699, Seq. ID No. 5705, Seq. ID No. 5709, Seq. ID No. 5729, Seq. ID No. 5733, Seq. ID No. 5763, Seq. ID No. 5765, Seq. ID No. 5767, Seq. ID No. 5771, Seq. ID No. 5783, Seq. ID No. 5791, Seq. ID No. 5797, Seq. ID No. 5885, Seq. ID No. 5889, Seq. ID No. 5893, Seq. ID No. 5895, Seq. ID No. 5899, Seq. ID No. 5901, Seq. ID No. 5905, Seq. ID No. 5909, Seq. ID No. 5921, Seq. ID No. 5923, Seq. ID No. 5927, Seq. ID No. 5939, Seq. ID No. 6027, Seq. ID No. 6043, Seq. ID No. 6047, Seq. ID No. 6059, Seq. ID No. 6067, Seq. ID No. 6089, Seq. ID No. 6091, Seq. ID No. 6107, Seq. ID No. 6111, Seq. ID No. 6117, Seq. ID No. 6161, Seq. ID No. 6163, Seq. ID No. 6165, Seq. ID No. 6169, Seq. ID No. 6183, Seq. ID No. 6185, Seq. ID No. 6189, Seq. ID No. 6191, Seq. ID No. 6197, Seq. ID No. 6203, Seq. ID No. 6205, Seq. ID No. 6209, Seq. ID No. 6221, Seq. ID No. 6223, Seq. ID No. 6225, Seq. ID No. 6227, Seq. ID No. 6229, Seq. ID No. 6235, Seq. ID No. 6237, Seq. ID No. 6243, Seq. ID No. 6245, Seq. ID No. 6249, Seq. ID No. 6253, Seq. ID No. 6263, Seq. ID No. 6265, Seq. ID No. 6273, Seq. ID No. 6275, Seq. ID No. 6285, Seq. ID No. 6289, Seq. ID No. 6301, Seq. ID No. 6303, Seq. ID No. 6363, Seq. ID No. 6377, Seq. ID No. 6381, Seq. ID No. 6383, Seq. ID No. 6415, Seq. ID No. 6427, Seq. ID No. 6431, Seq. ID No. 6473, Seq. ID No. 6497, Seq. ID No. 6571, Seq. ID No. 6581, Seq. ID No. 6593, Seq. ID No. 6599, Seq. ID No. 6631, and Seq. ID No.
 6639. 31. An isolated polynucleotide of an Alloiococcus otitidis genomic sequence, wherein the polynucleotide comprises a nucleotide sequence having at least about 70% identity to a nucleotide sequence contained within SEQ ID NO: 6651, a complement thereof, a degenerate variant thereof, and a fragment thereof.
 32. An isolated polypeptide encoded by a polynucleotide comprising a nucleotide sequence having at least about 70% identity to a nucleotide sequence selected from one of odd numbered sequences from SEQ ID NO: 1 to SEQ ID NO: 6649, a degenerate variant thereof, and a fragment thereof.
 33. The polypeptide of claim 32, wherein the polypeptide comprises an amino acid sequence having at least about 70% identity to an amino acid sequence chosen from one of the even-numbered sequences from SEQ ID NO: 2 to SEQ ID NO: 6650, a biological equivalent thereof, and a fragment thereof.
 34. The polypeptide of claim 32, wherein the polypeptide is a fusion polypeptide.
 35. The polypeptide of claim 32, which immunoreacts with seropositive serum of an individual infected with Alloiococcus otitidis.
 36. The polypeptide of claim 32, further defined as: (a) an Alloiococcus otitidis polypeptide predicted by SignalP algorithm analysis as having met all four criteria set out in the SignalP algorithm for a polypeptide having a signal peptide and predicted by HMM Signal P algorithm analysis as having a signal peptide; (b) an Alloiococcus otitidis polypeptide predicted by SignalP algorithm analysis as having met three of the four criteria set out in the SignalP algorithm for a polypeptide having a signal peptide and predicted by HMM SignalP algorithm analysis as having a signal peptide; (c) an Alloiococcus otitidis polypeptide predicted by HMM Signal P algorithm analysis as having a signal peptide; (d) an Alloiococcus otitidis polypeptide predicted by HMM SignalP algorithm analysis as being a non-secretory protein; (e) an Alloiococcus otitidis polypeptide identified by BlastP analysis; (f) an Alloiococcus otitidis polypeptide identified by Pfam analysis; (g) an Alloiococcus otitidis polypeptide identified using proteomics methodology as sharing homology with surface exposed proteins of Streptococcus pneumoniae; (h) an Alloiococcus otitidis lipoprotein; (i) an Alloiococcus otitidis polypeptide having a LPXTG motif, wherein the polypeptide is covalently attached to the peptidoglycan layer; (j) an Alloiococcus otitidis polypeptide, wherein the polypeptide is non-covalently associated with the peptidoglycan layer; (k) an Alloiococcus otitidis polypeptide having an RGDX motif wherein X is not a proline residue; (l) an Alloiococcus otitidis polypeptide predicted by BlastP as being involved in capsule biosynthesis and transport; (m) an Alloiococcus otitidis polypeptide identified by BlastP as being localized within the capsule loci of the Alloiococcus otitidis genome; (n) an Alloiococcus otitidis polypeptide predicted by BlastP as being associated with sporulation; (o) an Alloiococcus otitidis polypeptide encoded by unique ORFs identified by BlastP analysis as having a BlastP ‘E Value’ of >e⁻¹⁰; (p) an Alloiococcus otitidis polypeptide identified by Glimmer™ ORF finder program; (q) an Alloiococcus otitidis polypeptide identified by GeneMark™ ORF finder program; (r) an Alloiococcus otitidis polypeptide identified by an ORF finder program that searches for an ATG, GTG or TTG Start codon between a Stop-Stop region; and (s) an Alloiococcus otitidis polypeptide identified by an ORF finder program that searches for a transmembrane domain between two Stop codon and a Start codon immediately upstream of this transmembrane region.
 37. The Alloiococcus otitidis polypeptide of claim 36, wherein the polypeptide is predicted by SignalP algorithm analysis as having met all four criteria set out in the SignalP algorithm for a polypeptide having a signal peptide and predicted by HMM Signal P algorithm analysis as having a signal peptide; and is selected from one of Seq. ID No. 90, Seq. ID No. 128, Seq. ID No. 132, Seq. ID No. 134, Seq. ID No. 162, Seq. ID No. 164, Seq. ID No. 214, Seq. ID No. 216, Seq. ID No. 226, Seq. ID No. 250, Seq. ID No. 252, Seq. ID No. 288, Seq. ID No. 290, Seq. ID No. 370, Seq. ID No. 372, Seq. ID No. 376, Seq. ID No. 378, Seq. ID No. 498, Seq. ID No. 504, Seq. ID No. 506, Seq. ID No. 528, Seq. ID No. 550, Seq. ID No. 576, Seq. ID No. 618, Seq. ID No. 658, Seq. ID No. 660, Seq. ID No. 662, Seq. ID No. 676, Seq. ID No. 716, Seq. ID No. 718, Seq. ID No. 746, Seq. ID No. 748, Seq. ID No. 756, Seq. ID No. 758, Seq. ID No. 760, Seq. ID No. 762, Seq. ID No. 774, Seq. ID No. 808, Seq. ID No. 968, Seq. ID No. 974, Seq. ID No. 976, Seq. ID No. 1014, Seq. ID No. 1026, Seq. ID No. 1028, Seq. ID No. 1040, Seq. ID No. 1076, Seq. ID No. 1090, Seq. ID No. 1196, Seq. ID No. 1198, Seq. ID No. 1208, Seq. ID No. 1240, Seq. ID No. 1244, Seq. ID No. 1246, Seq. ID No. 1270, Seq. ID No. 1316, Seq. ID No. 1318, Seq. ID No. 1332, Seq. ID No. 1366, Seq. ID No. 1368, Seq. ID No. 1370, Seq. ID No. 1446, Seq. ID No. 1448, Seq. ID No. 1514, Seq. ID No. 1518, Seq. ID No. 1546, Seq. ID No. 1550, Seq. ID No. 1562, Seq. ID No. 1570, Seq. ID No. 1572, Seq. ID No. 1586, Seq. ID No. 1644, Seq. ID No. 1654, Seq. ID No. 1662, Seq. ID No. 1664, Seq. ID No. 1708, Seq. ID No. 1734, Seq. ID No. 1738, Seq. ID No. 1756, Seq. ID No. 1766, Seq. ID No. 1768, Seq. ID No. 1776, Seq. ID No. 1792, Seq. ID No. 1806, Seq. ID No. 1876, Seq. ID No. 1970, Seq. ID No. 1982, Seq. ID No. 2054, Seq. ID No. 2056, Seq. ID No. 2088, Seq. ID No. 2090, Seq. ID No. 2092, Seq. ID No. 2106, Seq. ID No. 2116, Seq. ID No. 2150, Seq. ID No. 2152, Seq. ID No. 2160, Seq. ID No. 2178, Seq. ID No. 2278, Seq. ID No. 2294, Seq. ID No. 2322, Seq. ID No. 2348, Seq. ID No. 2352, Seq. ID No. 2354, Seq. ID No. 2366, Seq. ID No. 2396, Seq. ID No. 2422, Seq. ID No. 2426, Seq. ID No. 2428, Seq. ID No. 2430, Seq. ID No. 2450, Seq. ID No. 2460, Seq. ID No. 2526, Seq. ID No. 2532, Seq. ID No. 2608, Seq. ID No. 2652, Seq. ID No. 2680, Seq. ID No. 2694, Seq. ID No. 2700, Seq. ID No. 2704, Seq. ID No. 2754, Seq. ID No. 2786, Seq. ID No. 2814, Seq. ID No. 2830, Seq. ID No. 2836, Seq. ID No. 2842, Seq. ID No. 2880, Seq. ID No. 2882, Seq. ID No. 2936, Seq. ID No. 2938, Seq. ID No. 2950,.Seq. ID No. 2966, Seq. ID No. 2968, Seq. ID No. 2974, Seq. ID No. 3008, Seq. ID No. 3010, Seq. ID No. 3012, Seq. ID No. 3030, Seq. ID No. 3032, Seq. ID No. 3110, Seq. ID No. 3112, Seq. ID No. 3220, Seq. ID No. 3224, Seq. ID No. 3274, Seq. ID No. 3298, Seq. ID No. 3332, Seq. ID No. 3336, Seq. ID No. 3342, Seq. ID No. 3350, Seq. ID No. 3354, Seq. ID No. 3356, Seq. ID No. 3378, Seq. ID No. 3392, Seq. ID No. 3426, Seq. ID No. 3450, Seq. ID No. 3494, Seq. ID No. 3574, Seq. ID No. 3612, Seq. ID No. 3620, Seq. ID No. 3690, Seq. ID No. 3754, Seq. ID No. 3756, Seq. ID No. 3766, Seq. ID No. 3782, Seq. ID No. 3784, Seq. ID No. 3852, Seq. ID No. 3904, Seq. ID No. 4006, Seq. ID No. 4008, Seq. ID No. 4028, Seq. ID No. 4074, Seq. ID No. 4138, Seq. ID No. 4142, Seq. ID No. 4144, Seq. ID No. 4146, Seq. ID No. 4226, Seq. ID No. 4344, Seq. ID No. 4386, Seq. ID No. 4400, Seq. ID No. 4470, Seq. ID No. 4484, Seq. ID No. 4494, Seq. ID No. 4496, Seq. ID No. 4534, Seq. ID No. 4700, Seq. ID No. 4710, Seq. ID No. 4712, Seq. ID No. 4736, Seq. ID No. 4828, Seq. ID No. 4872, Seq. ID No. 4874, Seq. ID No. 4880, Seq. ID No. 4922, Seq. ID No. 4982, Seq. ID No. 5116, Seq. ID No. 5268, Seq. ID No. 5342, Seq. ID No. 5388, Seq. ID No. 5466, Seq. ID No. 5468, Seq. ID No. 5480, Seq. ID No. 5498, Seq. ID No. 5514, Seq. ID No. 5544, Seq. ID No. 5546, Seq. ID No. 5568, Seq. ID No. 5588, Seq. ID No. 5590, Seq. ID No. 5592, Seq. ID No. 5612, Seq. ID No. 5622, Seq. ID No. 5642, Seq. ID No. 5682, Seq. ID No. 5720, Seq. ID No. 5772, Seq. ID No. 5784, Seq. ID No. 5896, Seq. ID No. 5900, Seq. ID No. 5902, Seq. ID No. 5928, Seq. ID No. 5930, Seq. ID No. 5940, Seq. ID No. 5988, Seq. ID No. 6014, Seq. ID No. 6088, Seq. ID No. 6090, Seq. ID No. 6092, Seq. ID No. 6094, Seq. ID No. 6096, Seq. ID No. 6104, Seq. ID No. 6170, Seq. ID No. 6186, Seq. ID No. 6188, Seq. ID No. 6196, Seq. ID No. 6198, Seq. ID No. 6204, Seq. ID No. 6206, Seq. ID No. 6222, Seq. ID No. 6224, Seq. ID No. 6230, Seq. ID No. 6292, Seq. ID No. 6416, Seq. ID No. 6418, Seq. ID No. 6474, Seq. ID No. 6508, Seq. ID No. 6544, Seq. ID No. 6596, Seq. ID No. 6598, Seq. ID No. 6600, Seq. ID No. 6602, and Seq. ID No.
 6604. 38. The Alloiococcus otitidis polypeptide of claim 36, wherein the polypeptide is predicted by SignalP algorithm analysis as having met three of the four criteria set out in the SignalP algorithm for a polypeptide having a signal peptide and predicted by HMM SignalP algorithm analysis as having a signal peptide; and is selected from one of Seq. ID No. 8, Seq. ID No. 12, Seq. ID No. 24, Seq. ID No. 46, Seq. ID No. 48, Seq. ID No. 54, Seq. ID No. 60, Seq. ID No. 66, Seq. ID No. 68, Seq. ID No. 88, Seq. ID No. 92, Seq. ID No. 140, Seq. ID No. 152, Seq. ID No. 160, Seq. ID No. 166, Seq. ID No. 170, Seq. ID No. 186, Seq. ID No. 212, Seq. ID No. 218, Seq. ID No. 236, Seq. ID No. 238, Seq. ID No. 240, Seq. ID No. 272, Seq. ID No. 286, Seq. ID No. 292, Seq. ID No. 328, Seq. ID No. 350, Seq. ID No. 386, Seq. ID No. 388, Seq. ID No. 408, Seq. ID No. 428, Seq. ID No. 432, Seq. ID No. 456, Seq. ID No. 458, Seq. ID No. 496, Seq. ID No. 500, Seq. ID No. 512, Seq. ID No. 514, Seq. ID No. 516, Seq. ID No. 526, Seq. ID No. 546, Seq. ID No. 548, Seq. ID No. 558, Seq. ID No. 570, Seq. ID No. 590, Seq. ID No. 592, Seq. ID No. 594, Seq. ID No. 596, Seq. ID No. 610, Seq. ID No. 638, Seq. ID No. 640, Seq. ID No. 642, Seq. ID No. 654, Seq. ID No. 670, Seq. ID No. 680, Seq. ID No. 720, Seq. ID No. 724, Seq. ID No. 740, Seq. ID No. 750, Seq. ID No. 752, Seq. ID No. 764, Seq. ID No. 766, Seq. ID No. 770, Seq. ID No. 778, Seq. ID No. 780, Seq. ID No. 782, Seq. ID No. 820, Seq. ID No. 896, Seq. ID No. 904, Seq. ID No. 906, Seq. ID No. 910, Seq. ID No. 936, Seq. ID No. 938, Seq. ID No. 952, Seq. ID No. 956, Seq. ID No. 980, Seq. ID No. 982, Seq. ID No. 984, Seq. ID No. 986, Seq. ID No. 1006, Seq. ID No. 1008, Seq. ID No. 1010, Seq. ID No. 1016, Seq. ID No. 1020, Seq. ID No. 1030, Seq. ID No. 1032, Seq. ID No. 1048, Seq. ID No. 1092, Seq. ID No. 1112, Seq. ID No. 1138, Seq. ID No. 1152, Seq. ID No. 1154, Seq. ID No. 1170, Seq. ID No. 1174, Seq. ID No. 1184, Seq. ID No. 1192, Seq. ID No. 1194, Seq. ID No. 1214, Seq. ID No. 1224, Seq. ID No. 1230, Seq. ID No. 1248, Seq. ID No. 1260, Seq. ID No. 1284, Seq. ID No. 1308, Seq. ID No. 1320, Seq. ID No. 1322, Seq. ID No. 1328, Seq. ID No. 1342, Seq. ID No. 1344, Seq. ID No. 1348, Seq. ID No. 1390, Seq. ID No. 1402, Seq. ID No. 1430, Seq. ID No. 1480, Seq. ID No. 1552, Seq. ID No. 1560, Seq. ID No. 1580, Seq. ID No. 1588, Seq. ID No. 1622, Seq. ID No. 1628, Seq. ID No. 1634, Seq. ID No. 1646, Seq. ID No. 1648, Seq. ID No. 1650, Seq. ID No. 1656, Seq. ID No. 1666, Seq. ID No. 1668, Seq. ID No. 1672, Seq. ID No. 1678, Seq. ID No. 1680, Seq. ID No. 1682, Seq. ID No. 1696, Seq. ID No. 1704, Seq. ID No. 1706, Seq. ID No. 1732, Seq. ID No. 1754, Seq. ID No. 1760, Seq. ID No. 1764, Seq. ID No. 1788, Seq. ID No. 1798, Seq. ID No. 1822, Seq. ID No. 1824, Seq. ID No. 1834, Seq. ID No. 1840, Seq. ID No. 1842, Seq. ID No. 1844, Seq. ID No. 1894, Seq. ID No. 1918, Seq. ID No. 1920, Seq. ID No. 1972, Seq. ID No. 1992, Seq. ID No. 2014, Seq. ID No. 2016, Seq. ID No. 2018, Seq. ID No. 2020, Seq. ID No. 2034, Seq. ID No. 2036, Seq. ID No. 2050, Seq. ID No. 2082, Seq. ID No. 2084, Seq. ID No. 2086, Seq. ID No. 2112, Seq. ID No. 2114, Seq. ID No. 2124, Seq. ID No. 2126, Seq. ID No. 2128, Seq. ID No. 2132, Seq. ID No. 2134, Seq. ID No. 2154, Seq. ID No. 2162, Seq. ID No. 2172, Seq. ID No. 2176, Seq. ID No. 2180, Seq. ID No. 2188, Seq. ID No. 2202, Seq. ID No. 2204, Seq. ID No. 2222, Seq. ID No. 2238, Seq. ID No. 2250, Seq. ID No. 2252, Seq. ID No. 2256, Seq. ID No. 2262, Seq. ID No. 2264, Seq. ID No. 2272, Seq. ID No. 2280, Seq. ID No. 2284, Seq. ID No. 2286, Seq. ID No. 2290, Seq. ID No. 2296, Seq. ID No. 2306, Seq. ID No. 2308, Seq. ID No. 2318, Seq. ID No. 2320, Seq. ID No. 2324, Seq. ID No. 2326, Seq. ID No. 2344, Seq. ID No. 2350, Seq. ID No. 2386, Seq. ID No. 2394, Seq. ID No. 2424, Seq. ID No. 2454, Seq. ID No. 2492, Seq. ID No. 2498, Seq. ID No. 2500, Seq. ID No. 2508, Seq. ID No. 2516, Seq. ID No. 2518, Seq. ID No. 2522, Seq. ID No. 2524, Seq. ID No. 2528, Seq. ID No. 2534, Seq. ID No. 2536, Seq. ID No. 2542, Seq. ID No. 2544, Seq. ID No. 2548, Seq. ID No. 2550, Seq. ID No. 2558, Seq. ID No. 2574, Seq. ID No. 2584, Seq. ID No. 2602, Seq. ID No. 2604, Seq. ID No. 2622, Seq. ID No. 2654, Seq. ID No. 2682, Seq. ID No. 2692, Seq. ID No. 2702, Seq. ID No. 2734, Seq. ID No. 2740, Seq. ID No. 2802, Seq. ID No. 2808, Seq. ID No. 2816, Seq. ID No. 2820, Seq. ID No. 2822, Seq. ID No. 2824, Seq. ID No. 2834, Seq. ID No. 2838, Seq. ID No. 2840, Seq. ID No. 2846, Seq. ID No. 2854, Seq. ID No. 2862, Seq. ID No. 2866, Seq. ID No. 2874, Seq. ID No. 2876, Seq. ID No. 2878, Seq. ID No. 2884, Seq. ID No. 2896, Seq. ID No. 2906, Seq. ID No. 2940, Seq. ID No. 2942, Seq. ID No. 2948, Seq. ID No. 2982, Seq. ID No. 2984, Seq. ID No. 2988, Seq. ID No. 2992, Seq. ID No. 2996, Seq. ID No. 3002, Seq. ID No. 3006, Seq. ID No. 3022, Seq. ID No. 3026, Seq. ID No. 3044, Seq. ID No. 3046, Seq. ID No. 3074, Seq. ID No. 3076, Seq. ID No. 3156, Seq. ID No. 3164, Seq. ID No. 3166, Seq. ID No. 3168, Seq. ID No. 3184, Seq. ID No. 3214, Seq. ID No. 3216, Seq. ID No. 3236, Seq. ID No. 3246, Seq. ID No. 3262, Seq. ID No. 3264, Seq. ID No. 3266, Seq. ID No. 3270, Seq. ID No. 3272, Seq. ID No. 3276, Seq. ID No. 3278, Seq. ID No. 3318, Seq. ID No. 3326, Seq. ID No. 3338, Seq. ID No. 3352, Seq. ID No. 3390, Seq. ID No. 3406, Seq. ID No. 3420, Seq. ID No. 3422, Seq. ID No. 3424, Seq. ID No. 3452, Seq. ID No. 3454, Seq. ID No. 3456, Seq. ID No. 3492, Seq. ID No. 3496, Seq. ID No. 3504, Seq. ID No. 3506, Seq. ID No. 3518, Seq. ID No. 3520, Seq. ID No. 3546, Seq. ID No. 3548, Seq. ID No. 3572, Seq. ID No. 3594, Seq. ID No. 3618, Seq. ID No. 3622, Seq. ID No. 3630, Seq. ID No. 3664, Seq. ID No. 3702, Seq. ID No. 3704, Seq. ID No. 3724, Seq. ID No. 3738, Seq. ID No. 3742, Seq. ID No. 3746, Seq. ID No. 3748, Seq. ID No. 3760, Seq. ID No. 3764, Seq. ID No. 3768, Seq. ID No. 3770, Seq. ID No. 3772, Seq. ID No. 3786, Seq. ID No. 3794, Seq. ID No. 3814, Seq. ID No. 3838, Seq. ID No. 3840, Seq. ID No. 3862, Seq. ID No. 3866, Seq. ID No. 3890, Seq. ID No. 3892, Seq. ID No. 3896, Seq. ID No. 3916, Seq. ID No. 3924, Seq. ID No. 3926, Seq. ID No. 3930, Seq. ID No. 3966, Seq. ID No. 3976, Seq. ID No. 3980, Seq. ID No. 3996, Seq. ID No. 3998, Seq. ID No. 4010, Seq. ID No. 4040, Seq. ID No. 4042, Seq. ID No. 4062, Seq. ID No. 4080, Seq. ID No. 4082, Seq. ID No. 4112, Seq. ID No. 4114, Seq. ID No. 4136, Seq. ID No. 4140, Seq. ID No. 4156, Seq. ID No. 4182, Seq. ID No. 4204, Seq. ID No. 4222, Seq. ID No. 4248, Seq. ID No. 4254, Seq. ID No. 4258, Seq. ID No. 4260, Seq. ID No. 4262, Seq. ID No. 4264, Seq. ID No. 4270, Seq. ID No. 4312, Seq. ID No. 4380, Seq. ID No. 4390, Seq. ID No. 4392, Seq. ID No. 4472, Seq. ID No. 4474, Seq. ID No. 4482, Seq. ID No. 4526, Seq. ID No. 4552, Seq. ID No. 4562, Seq. ID No. 4574, Seq. ID No. 4618, Seq. ID No. 4640, Seq. ID No. 4660, Seq. ID No. 4682, Seq. ID No. 4702, Seq. ID No. 4706, Seq. ID No. 4714, Seq. ID No. 4718, Seq. ID No. 4722, Seq. ID No. 4738, Seq. ID No. 4742, Seq. ID No. 4814, Seq. ID No. 4818, Seq. ID No. 4820, Seq. ID No. 4830, Seq. ID No. 4832, Seq. ID No. 4852, Seq. ID No. 4870, Seq. ID No. 4876, Seq. ID No. 4914, Seq. ID No. 4920, Seq. ID No. 4930, Seq. ID No. 4932, Seq. ID No. 4984, Seq. ID No. 4994, Seq. ID No. 5012, Seq. ID No. 5024, Seq. ID No. 5032, Seq. ID No. 5034, Seq. ID No. 5036, Seq. ID No. 5044, Seq. ID No. 5062, Seq. ID No. 5064, Seq. ID No. 5070, Seq. ID No. 5104, Seq. ID No. 5122, Seq. ID No. 5124, Seq. ID No. 5132, Seq. ID No. 5134, Seq. ID No. 5136, Seq. ID No. 5138, Seq. ID No. 5140, Seq. ID No. 5142, Seq. ID No. 5152, Seq. ID No. 5160, Seq. ID No. 5162, Seq. ID No. 5166, Seq. ID No. 5168, Seq. ID No. 5176, Seq. ID No. 5178, Seq. ID No. 5206, Seq. ID No. 5208, Seq. ID No. 5212, Seq. ID No. 5216, Seq. ID No. 5220, Seq. ID No. 5224, Seq. ID No. 5286, Seq. ID No. 5288, Seq. ID No. 5330, Seq. ID No. 5332, Seq. ID No. 5378, Seq. ID No. 5380, Seq. ID No. 5382, Seq. ID No. 5386, Seq. ID No. 5406, Seq. ID No. 5408, Seq. ID No. 5454, Seq. ID No. 5460, Seq. ID No. 5462, Seq. ID No. 5464, Seq. ID No. 5482, Seq. ID No. 5510, Seq. ID No. 5530, Seq. ID No. 5532, Seq. ID No. 5558, Seq. ID No. 5570, Seq. ID No. 5578, Seq. ID No. 5624, Seq. ID No. 5626, Seq. ID No. 5644, Seq. ID No. 5660, Seq. ID No. 5662, Seq. ID No. 5684, Seq. ID No. 5686, Seq. ID No. 5710, Seq. ID No. 5712, Seq. ID No. 5734, Seq. ID No. 5740, Seq. ID No. 5766, Seq. ID No. 5798, Seq. ID No. 5828, Seq. ID No. 5890, Seq. ID No. 5894, Seq. ID No. 5906, Seq. ID No. 5910, Seq. ID No. 5912, Seq. ID No. 5924, Seq. ID No. 5964, Seq. ID No. 5966, Seq. ID No. 6026, Seq. ID No. 6028, Seq. ID No. 6032, Seq. ID No. 6044, Seq. ID No. 6046, Seq. ID No. 6048, Seq. ID No. 6054, Seq. ID No. 6060, Seq. ID No. 6110, Seq. ID No. 6112, Seq. ID No. 6116, Seq. ID No. 6118, Seq. ID No. 6128, Seq. ID No. 6132, Seq. ID No. 6136, Seq. ID No. 6138, Seq. ID No. 6162, Seq. ID No. 6166, Seq. ID No. 6184, Seq. ID No. 6190, Seq. ID No. 6192, Seq. ID No. 6194, Seq. ID No. 6208, Seq. ID No. 6210, Seq. ID No. 6218, Seq. ID No. 6226, Seq. ID No. 6236, Seq. ID No. 6244, Seq. ID No. 6250, Seq. ID No. 6254, Seq. ID No. 6260, Seq. ID No. 6266, Seq. ID No. 6268, Seq. ID No. 6276, Seq. ID No. 6284, Seq. ID No. 6286, Seq. ID No. 6304, Seq. ID No. 6326, Seq. ID No. 6328, Seq. ID No. 6364, Seq. ID No. 6366, Seq. ID No. 6368, Seq. ID No. 6386, Seq. ID No. 6426, Seq. ID No. 6428, Seq. ID No. 6430, Seq. ID No. 6432, Seq. ID No. 6454, Seq. ID No. 6466, Seq. ID No. 6470, Seq. ID No. 6472, Seq. ID No. 6480, Seq. ID No. 6540, Seq. ID No. 6542, Seq. ID No. 6572, Seq. ID No. 6574, Seq. ID No. 6640, Seq. ID No. 6644, and Seq. ID No.
 6646. 39. The Alloiococcus otitidis polypeptide of claim 36, wherein the polypeptide is predicted by HMM SignalP algorithm analysis as having a signal peptide, and is selected from one of Seq. ID No. 4, Seq. ID No. 8, Seq. ID No. 10, Seq. ID No. 20, Seq. ID No. 22, Seq. ID No. 32, Seq. ID No. 34, Seq. ID No. 46, Seq. ID No. 48, Seq. ID No. 50, Seq. ID No. 54, Seq. ID No. 66, Seq. ID No. 68, Seq. ID No. 86, Seq. ID No. 88, Seq. ID No. 106, Seq. ID No. 112, Seq. ID No. 124, Seq. ID No. 132, Seq. ID No. 134, Seq. ID No. 142, Seq. ID No. 160, Seq. ID No. 162, Seq. ID No. 164, Seq. ID No. 172, Seq. ID No. 192, Seq. ID No. 210, Seq. ID No. 212, Seq. ID No. 214, Seq. ID No. 216, Seq. ID No. 218, Seq. ID No. 226, Seq. ID No. 236, Seq. ID No. 238, Seq. ID No. 250, Seq. ID No. 252, Seq. ID No. 256, Seq. ID No. 258, Seq. ID No. 260, Seq. ID No. 272, Seq. ID No. 274, Seq. ID No. 278, Seq. ID No. 286, Seq. ID No. 288, Seq. ID No. 290, Seq. ID No. 328, Seq. ID No. 330, Seq. ID No. 358, Seq. ID No. 360, Seq. ID No. 374, Seq. ID No. 376, Seq. ID No. 394, Seq. ID No. 402, Seq. ID No. 404, Seq. ID No. 456, Seq. ID No. 458, Seq. ID No. 478, Seq. ID No. 488, Seq. ID No. 490, Seq. ID No. 492, Seq. ID No. 494, Seq. ID No. 496, Seq. ID No. 498, Seq. ID No. 500, Seq. ID No. 504, Seq. ID No. 506, Seq. ID No. 510, Seq. ID No. 512, Seq. ID No. 514, Seq. ID No. 516, Seq. ID No. 526, Seq. ID No. 528, Seq. ID No. 546, Seq. ID No. 548, Seq. ID No. 550, Seq. ID No. 558, Seq. ID No. 568, Seq. ID No. 570, Seq. ID No. 576, Seq. ID No. 578, Seq. ID No. 580, Seq. ID No. 592, Seq. ID No. 594, Seq. ID No. 600, Seq. ID No. 618, Seq. ID No. 638, Seq. ID No. 640, Seq. ID No. 642, Seq. ID No. 644, Seq. ID No. 646, Seq. ID No. 648, Seq. ID No. 654, Seq. ID No. 656, Seq. ID No. 658, Seq. ID No. 660, Seq. ID No. 662, Seq. ID No. 668, Seq. ID No. 670, Seq. ID No. 676, Seq. ID No. 678, Seq. ID No. 680, Seq. ID No. 716, Seq. ID No. 718, Seq. ID No. 720, Seq. ID No. 722, Seq. ID No. 724, Seq. ID No. 726, Seq. ID No. 746, Seq. ID No. 748, Seq. ID No. 750, Seq. ID No. 752, Seq. ID No. 756, Seq. ID No. 758, Seq. ID No. 760, Seq. ID No. 762, Seq. ID No. 764, Seq. ID No. 766, Seq. ID No. 770, Seq. ID No. 778, Seq. ID No. 780, Seq. ID No. 782, Seq. ID No. 808, Seq. ID No. 810, Seq. ID No. 820, Seq. ID No. 826, Seq. ID No. 864, Seq. ID No. 894, Seq. ID No. 902, Seq. ID No. 936, Seq. ID No. 938, Seq. ID No. 942, Seq. ID No. 944, Seq. ID No. 956, Seq. ID No. 958, Seq. ID No. 968, Seq. ID No. 980, Seq. ID No. 982, Seq. ID No. 984, Seq. ID No. 986, Seq. ID No. 1002, Seq. ID No. 1004, Seq. ID No. 1006, Seq. ID No. 1008, Seq. ID No. 1010, Seq. ID No. 1012, Seq. ID No. 1014, Seq. ID No. 1016, Seq. ID No. 1020, Seq. ID No. 1030, Seq. ID No. 1032, Seq. ID No. 1034, Seq. ID No. 1036, Seq. ID No. 1038, Seq. ID No. 1040, Seq. ID No. 1046, Seq. ID No. 1056, Seq. ID No. 1076, Seq. ID No. 1078, Seq. ID No. 1106, Seq. ID No. 1108, Seq. ID No. 1132, Seq. ID No. 1136, Seq. ID No. 1138, Seq. ID No. 1140, Seq. ID No. 1152, Seq. ID No. 1166, Seq. ID No. 1168, Seq. ID No. 1170, Seq. ID No. 1174, Seq. ID No. 1184, Seq. ID No. 1196, Seq. ID No. 1198, Seq. ID No. 1204, Seq. ID No. 1214, Seq. ID No. 1224, Seq. ID No. 1228, Seq. ID No. 1230, Seq. ID No. 1238, Seq. ID No. 1244, Seq. ID No. 1246, Seq. ID No. 1260, Seq. ID No. 1266, Seq. ID No. 1268, Seq. ID No. 1270, Seq. ID No. 1272, Seq. ID No. 1284, Seq. ID No. 1288, Seq. ID No. 1290, Seq. ID No. 1292, Seq. ID No. 1296, Seq. ID No. 1298, Seq. ID No. 1304, Seq. ID No. 1306, Seq. ID No. 1316, Seq. ID No. 1318, Seq. ID No. 1320, Seq. ID No. 1326, Seq. ID No. 1328, Seq. ID No. 1330, Seq. ID No. 1332, Seq. ID No. 1338, Seq. ID No. 1342, Seq. ID No. 1344, Seq. ID No. 1348, Seq. ID No. 1350, Seq. ID No. 1352, Seq. ID No. 1354, Seq ID No. 1366, Seq. ID No. 1368, Seq. ID No. 1370, Seq. ID No. 1372, Seq. ID No. 1382, Seq. ID No. 1402, Seq. ID No. 1430, Seq. ID No. 1436, Seq. ID No. 1446, Seq. ID No. 1448, Seq. ID No. 1482, Seq. ID No. 1514, Seq. ID No. 1516, Seq. ID No. 1518, Seq. ID No. 1530, Seq. ID No. 1534, Seq. ID No. 1536, Seq. ID No. 1546, Seq. ID No. 1548, Seq. ID No. 1552, Seq. ID No. 1554, Seq. ID No. 1560, Seq. ID No. 1562, Seq. ID No. 1564, Seq. ID No. 1572, Seq. ID No. 1580, Seq. ID No. 1584, Seq. ID No. 1586, Seq. ID No. 1622, Seq. ID No. 1634, Seq. ID No. 1640, Seq. ID No. 1644, Seq. ID No. 1646, Seq. ID No. 1648, Seq. ID No. 1650, Seq. ID No. 1654, Seq. ID No. 1662, Seq. ID No. 1664, Seq. ID No. 1666, Seq. ID No. 1672, Seq. ID No. 1674, Seq. ID No. 1678, Seq. ID No. 1680, Seq. ID No. 1682, Seq. ID No. 1694, Seq. ID No. 1708, Seq. ID No. 1712, Seq. ID No. 1732, Seq. ID No. 1734, Seq. ID No. 1738, Seq. ID No. 1754, Seq. ID No. 1756, Seq. ID No. 1758, Seq. ID No. 1766, Seq. ID No. 1768, Seq. ID No. 1772, Seq. ID No. 1782, Seq. ID No. 1788, Seq. ID No. 1792, Seq. ID No. 1798, Seq. ID No. 1806, Seq. ID No. 1820, Seq. ID No. 1822, Seq. ID No. 1824, Seq. ID No. 1840, Seq. ID No. 1858, Seq. ID No. 1870, Seq. ID No. 1876, Seq. ID No. 1892, Seq. ID No. 1894, Seq. ID No. 1896, Seq. ID No. 1916, Seq. ID No. 1918, Seq. ID No. 1920, Seq. ID No. 1924, Seq. ID No. 1928, Seq. ID No. 1930, Seq. ID No. 1970, Seq. ID No. 1982, Seq. ID No. 1992, Seq. ID No. 1994, Seq. ID No. 2006, Seq. ID No. 2014, Seq. ID No. 2018, Seq. ID No. 2020, Seq. ID No. 2026, Seq. ID No. 2028, Seq. ID No. 2034, Seq. ID No. 2036, Seq. ID No. 2042, Seq. ID No. 2050, Seq. ID No. 2054, Seq. ID No. 2056, Seq. ID No. 2088, Seq. ID No. 2090, Seq. ID No. 2092, Seq. ID No. 2106, Seq. ID No. 2108, Seq. ID No. 2110, Seq. ID No. 2114, Seq. ID No. 2116, Seq. ID No. 2122, Seq. ID No. 2124, Seq. ID No. 2126, Seq. ID No. 2128, Seq. ID No. 2150, Seq. ID No. 2152, Seq. ID No. 2156, Seq. ID No. 2158, Seq. ID No. 2160, Seq. ID No. 2172, Seq. ID No. 2174, Seq. ID No. 2178, Seq. ID No. 2188, Seq. ID No. 2192, Seq. ID No. 2206, Seq. ID No. 2238, Seq. ID No. 2240, Seq. ID No. 2246, Seq. ID No. 2250, Seq. ID No. 2252, Seq. ID No. 2256, Seq. ID No. 2260, Seq. ID No. 2272, Seq. ID No. 2284, Seq. ID No. 2290, Seq. ID No. 2292, Seq. ID No. 2294, Seq. ID No. 2296, Seq. ID No. 2304, Seq. ID No. 2306, Seq. ID No. 2308, Seq. ID No. 2318, Seq. ID No. 2320, Seq. ID No. 2322, Seq. ID No. 2324, Seq. ID No. 2326, Seq. ID No. 2328, Seq. ID No. 2330, Seq. ID No. 2334, Seq. ID No. 2344, Seq. ID No. 2348, Seq. ID No. 2350, Seq. ID No. 2352, Seq. ID No. 2354, Seq. ID No. 2356, Seq. ID No. 2358, Seq. ID No. 2366, Seq. ID No. 2368, Seq. ID No. 2372, Seq. ID No. 2376, Seq. ID No. 2388, Seq. ID No. 2390, Seq. ID No. 2392, Seq. ID No. 2394, Seq. ID No. 2408, Seq. ID No. 2420, Seq. ID No. 2422, Seq. ID No. 2426, Seq. ID No. 2428, Seq. ID No. 2430, Seq. ID No. 2434, Seq. ID No. 2450, Seq. ID No. 2460, Seq. ID No. 2488, Seq. ID No. 2490, Seq. ID No. 2492, Seq. ID No. 2494, Seq. ID No. 2498, Seq. ID No. 2500, Seq. ID No. 2502, Seq. ID No. 2504, Seq. ID No. 2508, Seq. ID No. 2516, Seq. ID No. 2518, Seq. ID No. 2524, Seq. ID No. 2526, Seq. ID No. 2528, Seq. ID No. 2532, Seq. ID No. 2534, Seq. ID No. 2536, Seq. ID No. 2538, Seq. ID No. 2542, Seq. ID No. 2544, Seq. ID No. 2546, Seq. ID No. 2556, Seq. ID No. 2558, Seq. ID No. 2566, Seq. ID No. 2570, Seq. ID No. 2572, Seq. ID No. 2584, Seq. ID No. 2592, Seq. ID No. 2598, Seq. ID No. 2600, Seq. ID No. 2602, Seq. ID No. 2608, Seq. ID No. 2612, Seq. ID No. 2622, Seq. ID No. 2628, Seq. ID No. 2630, Seq. ID No. 2652, Seq. ID No. 2680, Seq. ID No. 2682, Seq. ID No. 2684, Seq. ID No. 2692, Seq. ID No. 2694, Seq. ID No. 2696, Seq. ID No. 2698, Seq. ID No. 2700, Seq. ID No. 2702, Seq. ID No. 2704, Seq. ID No. 2706, Seq. ID No. 2708, Seq. ID No. 2718, Seq. ID No. 2730, Seq. ID No. 2732, Seq. ID No. 2734, Seq. ID No. 2784, Seq. ID No. 2786, Seq. ID No. 2802, Seq. ID No. 2810, Seq. ID No. 2814, Seq. ID No. 2816, Seq. ID No. 2820, Seq. ID No. 2822, Seq. ID No. 2824, Seq. ID No. 2832, Seq. ID No. 2834, Seq. ID No. 2836, Seq. ID No. 2838, Seq. ID No. 2840, Seq. ID No. 2842, Seq. ID No. 2846, Seq. ID No. 2854, Seq. ID No. 2856, Seq. ID No. 2860, Seq. ID No. 2862, Seq. ID No. 2874, Seq. ID No. 2882, Seq. ID No. 2894, Seq. ID No. 2906, Seq. ID No. 2936, Seq. ID No. 2938, Seq. ID No. 2940, Seq. ID No. 2942, Seq. ID No. 2948, Seq. ID No. 2950, Seq. ID No. 2952, Seq. ID No. 2970, Seq. ID No. 2974, Seq. ID No. 2976, Seq. ID No. 2978, Seq. ID No. 2982, Seq. ID No. 2984, Seq. ID No. 2988, Seq. ID No. 2992, Seq. ID No. 2996, Seq. ID No. 2998, Seq. ID No. 3006, Seq. ID No. 3008, Seq. ID No. 3010, Seq. ID No. 3012, Seq. ID No. 3014, Seq. ID No. 3024, Seq. ID No. 3026, Seq. ID No. 3028, Seq. ID No. 3030, Seq. ID No. 3032, Seq. ID No. 3044, Seq. ID No. 3056, Seq. ID No. 3064, Seq. ID No. 3072, Seq. ID No. 3074, Seq. ID No. 3076, Seq. ID No. 3078, Seq. ID No. 3120, Seq. ID No. 3122, Seq. ID No. 3124, Seq. ID No. 3146, Seq. ID No. 3156, Seq. ID No. 3158, Seq. ID No. 3164, Seq. ID No. 3166, Seq. ID No. 3174, Seq. ID No. 3184, Seq. ID No. 3194, Seq. ID No. 3202, Seq. ID No. 3214, Seq. ID No. 3216, Seq. ID No. 3218, Seq. ID No. 3220, Seq. ID No. 3242, Seq. ID No. 3244, Seq. ID No. 3246, Seq. ID No. 3250, Seq. ID No. 3256, Seq. ID No. 3258, Seq. ID No. 3262, Seq. ID No. 3264, Seq. ID No. 3270, Seq. ID No. 3276, Seq. ID No. 3278, Seq. ID No. 3298, Seq. ID No. 3318, Seq. ID No. 3324, Seq. ID No. 3326, Seq. ID No. 3332, Seq. ID No. 3336, Seq. ID No. 3338, Seq. ID No. 3340, Seq. ID No. 3350, Seq. ID No. 3352, Seq. ID No. 3354, Seq. ID No. 3356, Seq. ID No. 3358, Seq. ID No. 3360, Seq. ID No. 3376, Seq. ID No. 3378, Seq. ID No. 3390, Seq. ID No. 3392, Seq. ID No. 3396, Seq. ID No. 3406, Seq. ID No. 3416, Seq. ID No. 3422, Seq. ID No. 3426, Seq. ID No. 3428, Seq. ID No. 3434, Seq. ID No. 3442, Seq. ID No. 3450, Seq. ID No. 3452, Seq. ID No. 3454, Seq. ID No. 3456, Seq. ID No. 3458, Seq. ID No. 3464, Seq. ID No. 3482, Seq. ID No. 3492, Seq. ID No. 3494, Seq. ID No. 3504, Seq. ID No. 3506, Seq. ID No. 3518, Seq. ID No. 3520, Seq. ID No. 3528, Seq. ID No. 3532, Seq. ID No. 3540, Seq. ID No. 3562, Seq. ID No. 3574, Seq. ID No. 3582, Seq. ID No. 3588, Seq. ID No. 3594, Seq. ID No. 3596, Seq. ID No. 3612, Seq. ID No. 3618, Seq. ID No. 3620, Seq. ID No. 3622, Seq. ID No. 3626, Seq. ID No. 3630, Seq. ID No. 3636, Seq. ID No. 3678, Seq. ID No. 3680, Seq. ID No. 3690, Seq. ID No. 3718, Seq. ID No. 3724, Seq. ID No. 3728, Seq. ID No. 3742, Seq. ID No. 3746, Seq. ID No. 3754, Seq. ID No. 3756, Seq. ID No. 3758, Seq. ID No. 3762, Seq. ID No. 3764, Seq. ID No. 3766, Seq. ID No. 3782, Seq. ID No. 3784, Seq. ID No. 3794, Seq. ID No. 3800, Seq. ID No. 3808, Seq. ID No. 3814, Seq. ID No. 3816, Seq. ID No. 3818, Seq. ID No. 3838, Seq. ID No. 3840, Seq. ID No. 3850, Seq. ID No. 3852, Seq. ID No. 3854, Seq. ID No. 3860, Seq. ID No. 3862, Seq. ID No. 3864, Seq. ID No. 3866, Seq. ID No. 3880, Seq. ID No. 3890, Seq. ID No. 3892, Seq. ID No. 3896, Seq. ID No. 3904, Seq. ID No. 3916, Seq. ID No. 3924, Seq. ID No. 3926, Seq. ID No. 3960, Seq. ID No. 3964, Seq. ID No. 3974, Seq. ID No. 3976, Seq. ID No. 3994, Seq. ID No. 3996, Seq. ID No. 3998, Seq. ID No. 4006, Seq. ID No. 4008, Seq. ID No. 4010, Seq. ID No. 4026, Seq. ID No. 4028, Seq. ID No. 4040, Seq. ID No. 4042, Seq. ID No. 4044, Seq. ID No. 4046, Seq. ID No. 4048, Seq. ID No. 4050, Seq. ID No. 4062, Seq. ID No. 4072, Seq. ID No. 4074, Seq. ID No. 4080, Seq. ID No. 4082, Seq. ID No. 4084, Seq. ID No. 4102, Seq. ID No. 4104, Seq. ID No. 4112, Seq. ID No. 4134, Seq. ID No. 4136, Seq. ID No. 4138, Seq. ID No. 4140, Seq. ID No. 4142, Seq. ID No. 4144, Seq. ID No. 4146, Seq. ID No. 4152, Seq. ID No. 4154, Seq. ID No. 4182, Seq. ID No. 4222, Seq. ID No. 4224, Seq. ID No. 4226, Seq. ID No. 4228, Seq. ID No. 4232, Seq. ID No. 4234, Seq. ID No. 4242, Seq. ID No. 4248, Seq. ID No. 4254, Seq. ID No. 4258, Seq. ID No. 4260, Seq. ID No. 4262, Seq. ID No. 4264, Seq. ID No. 4266, Seq. ID No. 4270, Seq. ID No. 4276, Seq. ID No. 4286, Seq. ID No. 4288, Seq. ID No. 4298, Seq. ID No. 4308, Seq. ID No. 4312, Seq. ID No. 4314, Seq. ID No. 4344, Seq. ID No. 4380, Seq. ID No. 4386, Seq. ID No. 4390, Seq. ID No. 4392, Seq. ID No. 4400, Seq. ID No. 4404, Seq. ID No. 4438, Seq. ID No. 4440, Seq. ID No. 4442, Seq. ID No. 4470, Seq. ID No. 4474, Seq. ID No. 4482, Seq. ID No. 4484, Seq. ID No. 4486, Seq. ID No. 4494, Seq. ID No. 4496, Seq. ID No. 4498, Seq. ID No. 4514, Seq. ID No. 4516, Seq. ID No. 4528, Seq. ID No. 4530, Seq. ID No. 4534, Seq. ID No. 4588, Seq. ID No. 4590, Seq. ID No. 4640, Seq. ID No. 4642, Seq. ID No. 4644, Seq. ID No. 4660, Seq. ID No. 4682, Seq. ID No. 4688, Seq. ID No. 4696, Seq. ID No. 4706, Seq. ID No. 4708, Seq. ID No. 4710, Seq. ID No. 4712, Seq. ID No. 4716, Seq. ID No. 4718, Seq. ID No. 4738, Seq. ID No. 4760, Seq. ID No. 4814, Seq. ID No. 4828, Seq. ID No. 4854, Seq. ID No. 4864, Seq. ID No. 4870, Seq. ID No. 4872, Seq. ID No. 4874, Seq. ID No. 4876, Seq. ID No. 4920, Seq. ID No. 4922, Seq. ID No. 4924, Seq. ID No. 4930, Seq. ID No. 4932, Seq. ID No. 4950, Seq. ID No. 4952, Seq. ID No. 4976, Seq. ID No. 4988, Seq. ID No. 5000, Seq. ID No. 5014, Seq. ID No. 5032, Seq. ID No. 5062, Seq. ID No. 5064, Seq. ID No. 5070, Seq. ID No. 5086, Seq. ID No. 5104, Seq. ID No. 5116, Seq. ID No. 5124, Seq. ID No. 5126, Seq. ID No. 5130, Seq. ID No. 5132, Seq. ID No. 5134, Seq. ID No. 5136, Seq. ID No. 5138, Seq. ID No. 5140, Seq. ID No. 5142, Seq. ID No. 5160, Seq. ID No. 5166, Seq. ID No. 5176, Seq. ID No. 5198, Seq. ID No. 5200, Seq. ID No. 5206, Seq. ID No. 5208, Seq. ID No. 5214, Seq. ID No. 5220, Seq. ID No. 5224, Seq. ID No. 5268, Seq. ID No. 5274, Seq. ID No. 5276, Seq. ID No. 5278, Seq. ID No. 5280, Seq. ID No. 5282, Seq. ID No. 5286, Seq. ID No. 5328, Seq. ID No. 5330, Seq. ID No. 5332, Seq. ID No. 5342, Seq. ID No. 5378, Seq. ID No. 5380, Seq. ID No. 5386, Seq. ID No. 5388, Seq. ID No. 5406, Seq. ID No. 5414, Seq. ID No. 5416, Seq. ID No. 5434, Seq. ID No. 5454, Seq. ID No. 5460, Seq. ID No. 5462, Seq. ID No. 5464, Seq. ID No. 5466, Seq. ID No. 5492, Seq. ID No. 5498, Seq. ID No. 5510, Seq. ID No. 5514, Seq. ID No. 5516, Seq. ID No. 5518, Seq. ID No. 5526, Seq. ID No. 5530, Seq. ID No. 5532, Seq. ID No. 5534, Seq. ID No. 5544, Seq. ID No. 5546, Seq. ID No. 5570, Seq. ID No. 5588, Seq. ID No. 5590, Seq. ID No. 5592, Seq. ID No. 5594, Seq. ID No. 5596, Seq. ID No. 5598, Seq. ID No. 5610, Seq. ID No. 5612, Seq. ID No. 5622, Seq. ID No. 5624, Seq. ID No. 5626, Seq. ID No. 5634, Seq. ID No. 5638, Seq. ID No. 5640, Seq. ID No. 5642, Seq. ID No. 5644, Seq. ID No. 5650, Seq. ID No. 5660, Seq. ID No. 5668, Seq. ID No. 5682, Seq. ID No. 5684, Seq. ID No. 5686, Seq. ID No. 5688, Seq. ID No. 5690, Seq. ID No. 5700, Seq. ID No. 5704, Seq. ID No. 5706, Seq. ID No. 5710, Seq. ID No. 5712, Seq. ID No. 5720, Seq. ID No. 5730, Seq. ID No. 5734, Seq. ID No. 5736, Seq. ID No. 5740, Seq. ID No. 5764, Seq. ID No. 5766, Seq. ID No. 5768, Seq. ID No. 5772, Seq. ID No. 5784, Seq. ID No. 5786, Seq. ID No. 5792, Seq. ID No. 5798, Seq. ID No. 5830, Seq. ID No. 5880, Seq. ID No. 5884, Seq. ID No. 5886, Seq. ID No. 5890, Seq. ID No. 5894, Seq. ID No. 5896, Seq. ID No. 5900, Seq. ID No. 5902, Seq. ID No. 5906, Seq. ID No. 5910, Seq. ID No. 5922, Seq. ID No. 5924, Seq. ID No. 5928, Seq. ID No. 5930, Seq. ID No. 5940, Seq. ID No. 6024, Seq. ID No. 6026, Seq. ID No. 6028, Seq. ID No. 6044, Seq. ID No. 6048, Seq. ID No. 6054, Seq. ID No. 6060, Seq. ID No. 6064, Seq. ID No. 6068, Seq. ID No. 6088, Seq. ID No. 6090, Seq. ID No. 6092, Seq. ID No. 6096, Seq. ID No. 6104, Seq. ID No. 6108, Seq. ID No. 6110, Seq. ID No. 6112, Seq. ID No. 6116, Seq. ID No. 6118, Seq. ID No. 6136, Seq. ID No. 6138, Seq. ID No. 6160, Seq. ID No. 6162, Seq. ID No. 6164, Seq. ID No. 6166, Seq. ID No. 6170, Seq. ID No. 6184, Seq. ID No. 6186, Seq. ID No. 6188, Seq. ID No. 6190, Seq. ID No. 6192, Seq. ID No. 6198, Seq. ID No. 6204, Seq. ID No. 6206, Seq. ID No. 6210, Seq. ID No. 6218, Seq. ID No. 6222, Seq. ID No. 6224, Seq. ID No. 6226, Seq. ID No. 6228, Seq. ID No. 6230, Seq. ID No. 6236, Seq. ID No. 6238, Seq. ID No. 6242, Seq. ID No. 6244, Seq. ID No. 6246, Seq. ID No. 6250, Seq. ID No. 6254, Seq. ID No. 6260, Seq. ID No. 6264, Seq. ID No. 6266, Seq. ID No. 6268, Seq. ID No. 6274, Seq. ID No. 6276, Seq. ID No. 6284, Seq. ID No. 6286, Seq. ID No. 6290, Seq. ID No. 6302, Seq. ID No. 6304, Seq. ID No. 6326, Seq. ID No. 6328, Seq. ID No. 6364, Seq. ID No. 6366, Seq. ID No. 6378, Seq. ID No. 6382, Seq. ID No. 6384, Seq. ID No. 6416, Seq. ID No. 6426, Seq. ID No. 6428, Seq. ID No. 6430, Seq. ID No. 6432, Seq. ID No. 6474, Seq. ID No. 6480, Seq. ID No. 6498, Seq. ID No. 6518, Seq. ID No. 6542, Seq. ID No. 6544, Seq. ID No. 6556, Seq. ID No. 6558, Seq. ID No. 6572, Seq. ID No. 6574, Seq. ID No. 6582, Seq. ID No. 6594, Seq. ID No. 6596, Seq. ID No. 6598, Seq. ID No. 6600, Seq. ID No. 6602, Seq. ID No. 6604, Seq. ID No. 6632, Seq. ID No. 6638, Seq. ID No. 6640, Seq. ID No. 6644, Seq. ID No. 6646, and Seq. ID No.
 6650. 40. The Alloiococcus otitidis polypeptide of claim 36, wherein the polypeptide is predicted by HMM SignalP algorithm analysis as being a non-secretory protein, and is selected from one of Seq. ID No. 2, Seq. ID No. 6, Seq. ID No. 12, Seq. ID No. 14, Seq. ID No. 16, Seq. ID No. 18, Seq. ID No. 24, Seq. ID No. 26, Seq. ID No. 28, Seq. ID No. 30, Seq. ID No. 36, Seq. ID No. 38, Seq. ID No. 40, Seq. ID No. 42, Seq. ID No. 44, Seq. ID No. 52, Seq. ID No. 56, Seq. ID No. 58, Seq. ID No. 60, Seq. ID No. 62, Seq. ID No. 64, Seq. ID No. 70, Seq. ID No. 72, Seq. ID No. 74, Seq. ID No. 76, Seq. ID No. 78, Seq. ID No. 80, Seq. ID No. 82, Seq. ID No. 84, Seq. ID No. 90, Seq. ID No. 92, Seq. ID No. 94, Seq. ID No. 96, Seq. ID No. 98, Seq. ID No. 100, Seq. ID No. 102, Seq. ID No. 104, Seq. ID No. 108, Seq. ID No. 110, Seq. ID No. 114, Seq. ID No. 116, Seq. ID No. 118, Seq. ID No. 120, Seq. ID No. 122, Seq. ID No. 126, Seq. ID No. 128, Seq. ID No. 130, Seq. ID No. 136, Seq. ID No. 138, Seq. ID No. 140, Seq. ID No. 144, Seq. ID No. 146, Seq. ID No. 148, Seq. ID No. 150, Seq. ID No. 152, Seq. ID No. 154, Seq. ID No. 156, Seq. ID No. 158, Seq. ID No. 166, Seq. ID No. 168, Seq. ID No. 170, Seq. ID No. 174, Seq. ID No. 176, Seq. ID No. 178, Seq. ID No. 180, Seq. ID No. 182, Seq. ID No. 184, Seq. ID No. 186, Seq. ID No. 188, Seq. ID No. 190, Seq. ID No. 194, Seq. ID No. 196, Seq. ID No. 198, Seq. ID No. 200, Seq. ID No. 202, Seq. ID No. 204, Seq. ID No. 206, Seq. ID No. 208, Seq. ID No. 220, Seq. ID No. 222, Seq. ID No. 224, Seq. ID No. 228, Seq. ID No. 230, Seq. ID No. 232, Seq. ID No. 234, Seq. ID No. 240, Seq. ID No. 242, Seq. ID No. 244, Seq. ID No. 246, Seq. ID No. 248, Seq. ID No. 254, Seq. ID No. 262, Seq. ID No. 264, Seq. ID No. 266, Seq. ID No. 268, Seq. ID No. 270, Seq. ID No. 276, Seq. ID No. 280, Seq. ID No. 282, Seq. ID No. 284, Seq. ID No. 292, Seq. ID No. 294, Seq. ID No. 296, Seq. ID No. 298, Seq. ID No. 300, Seq. ID No. 302, Seq. ID No. 304, Seq. ID No. 306, Seq. ID No. 308, Seq. ID No. 310, Seq. ID No. 312, Seq. ID No. 314, Seq. ID No. 316, Seq. ID No. 318, Seq. ID No. 320, Seq. ID No. 322, Seq. ID No. 324, Seq. ID No. 326, Seq. ID No. 332, Seq. ID No. 334, Seq. ID No. 336, Seq. ID No. 338, Seq. ID No. 340, Seq. ID No. 342, Seq. ID No. 344, Seq. ID No. 346, Seq. ID No. 348, Seq. ID No. 350, Seq. ID No. 352, Seq. ID No. 354, Seq. ID No. 356, Seq. ID No. 362, Seq. ID No. 364, Seq. ID No. 366, Seq. ID No. 368, Seq. ID No. 370, Seq. ID No. 372, Seq. ID No. 378, Seq. ID No. 380, Seq. ID No. 382, Seq. ID No. 384, Seq. ID No. 386, Seq. ID No. 388, Seq. ID No. 390, Seq. ID No. 392, Seq. ID No. 396, Seq. ID No. 398, Seq. ID No. 400, Seq. ID No. 406, Seq. ID No. 408, Seq. ID No. 410, Seq. ID No. 412, Seq. ID No. 414, Seq. ID No. 416, Seq. ID No. 418, Seq. ID No. 420, Seq. ID No. 422, Seq. ID No. 424, Seq. ID No. 426, Seq. ID No. 428, Seq. ID No. 430, Seq. ID No. 432, Seq. ID No. 434, Seq. ID No. 436, Seq. ID No. 438, Seq. ID No. 440, Seq. ID No. 442, Seq. ID No. 444, Seq. ID No. 446, Seq. ID No. 448, Seq. ID No. 450, Seq. ID No. 452, Seq. ID No. 454, Seq. ID No. 460, Seq. ID No. 462, Seq. ID No. 464, Seq. ID No. 466, Seq. ID No. 468, Seq. ID No. 470, Seq. ID No. 472, Seq. ID No. 474, Seq. ID No. 476, Seq. ID No. 480, Seq. ID No. 482, Seq. ID No. 484, Seq. ID No. 486, Seq. ID No. 502, Seq. ID No. 508, Seq. ID No. 518, Seq. ID No. 520, Seq. ID No. 522, Seq. ID No. 524, Seq. ID No. 530, Seq. ID No. 532, Seq. ID No. 534, Seq. ID No. 536, Seq. ID No. 538, Seq. ID No. 540, Seq. ID No. 542, Seq. ID No. 544, Seq. ID No. 552, Seq. ID No. 554, Seq. ID No. 556, Seq. ID No. 560, Seq. ID No. 562, Seq. ID No. 564, Seq. ID No. 566, Seq. ID No. 572, Seq. ID No. 574, Seq. ID No. 582, Seq. ID No. 584, Seq. ID No. 586, Seq. ID No. 588, Seq. ID No. 590, Seq. ID No. 596, Seq. ID No. 598, Seq. ID No. 602, Seq. ID No. 604, Seq. ID No. 606, Seq. ID No. 608, Seq. ID No. 610, Seq. ID No. 612, Seq. ID No. 614, Seq. ID No. 616, Seq. ID No. 620, Seq. ID No. 622, Seq. ID No. 624, Seq. ID No. 626, Seq. ID No. 628, Seq. ID No. 630, Seq. ID No. 632, Seq. ID No. 634, Seq. ID No. 636, Seq. ID No. 650, Seq. ID No. 652, Seq. ID No. 664, Seq. ID No. 666, Seq. ID No. 672, Seq. ID No. 674, Seq. ID No. 682, Seq. ID No. 684, Seq. ID No. 686, Seq. ID No. 688, Seq. ID No. 690, Seq. ID No. 692, Seq. ID No. 694, Seq. ID No. 696, Seq. ID No. 698, Seq. ID No. 700, Seq. ID No. 702, Seq. ID No. 704, Seq. ID No. 706, Seq. ID No. 708, Seq. ID No. 710, Seq. ID No. 712, Seq. ID No. 714, Seq. ID No. 728, Seq. ID No. 730, Seq. ID No. 732, Seq. ID No. 734, Seq. ID No. 736, Seq. ID No. 738, Seq. ID No. 740, Seq. ID No. 742, Seq. ID No. 744, Seq. ID No. 754, Seq. ID No. 768, Seq. ID No. 772, Seq. ID No. 774, Seq. ID No. 776, Seq. ID No. 784, Seq. ID No. 786, Seq. ID No. 788, Seq. ID No. 790, Seq. ID No. 792, Seq. ID No. 794, Seq. ID No. 796, Seq. ID No. 798, Seq. ID No. 800, Seq. ID No. 802, Seq. ID No. 804, Seq. ID No. 806, Seq. ID No. 812, Seq. ID No. 814, Seq. ID No. 816, Seq. ID No. 818, Seq. ID No. 822, Seq. ID No. 824, Seq. ID No. 828, Seq. ID No. 830, Seq. ID No. 832, Seq. ID No. 834, Seq. ID No. 836, Seq. ID No. 838, Seq. ID No. 840, Seq. ID No. 842, Seq. ID No. 844, Seq. ID No. 846, Seq. ID No. 848, Seq. ID No. 850, Seq. ID No. 852, Seq. ID No. 854, Seq. ID No. 856, Seq. ID No. 858, Seq. ID No. 860, Seq. ID No. 862, Seq. ID No. 866, Seq. ID No. 868, Seq. ID No. 870, Seq. ID No. 872, Seq. ID No. 874, Seq. ID No. 876, Seq. ID No. 878, Seq. ID No. 880, Seq. ID No. 882, Seq. ID No. 884, Seq. ID No. 886, Seq. ID No. 888, Seq. ID No. 890, Seq. ID No. 892, Seq. ID No. 896, Seq. ID No. 898, Seq. ID No. 900, Seq. ID No. 904, Seq. ID No. 906, Seq. ID No. 908, Seq. ID No. 910, Seq. ID No. 912, Seq. ID No. 914, Seq. ID No. 916, Seq. ID No. 918, Seq. ID No. 920, Seq. ID No. 922, Seq. ID No. 924, Seq. ID No. 926, Seq. ID No. 928, Seq. ID No. 930, Seq. ID No. 932, Seq. ID No. 934, Seq. ID No. 940, Seq. ID No. 946, Seq. ID No. 948, Seq. ID No. 950, Seq. ID No. 952, Seq. ID No. 954, Seq. ID No. 960, Seq. ID No. 962, Seq. ID No. 964, Seq. ID No. 966, Seq. ID No. 970, Seq. ID No. 972, Seq. ID No. 974, Seq. ID No. 976, Seq. ID No. 978, Seq. ID No. 988, Seq. ID No. 990, Seq. ID No. 992, Seq. ID No. 994, Seq. ID No. 996, Seq. ID No. 998, Seq. ID No. 1000, Seq. ID No. 1018, Seq. ID No. 1022, Seq. ID No. 1024, Seq. ID No. 1026, Seq. ID No. 1028, Seq. ID No. 1042, Seq. ID No. 1044, Seq. ID No. 1048, Seq. ID No. 1050, Seq. ID No. 1052, Seq. ID No. 1054, Seq. ID No. 1058, Seq. ID No. 1060, Seq. ID No. 1062, Seq. ID No. 1064, Seq. ID No. 1066, Seq. ID No. 1068, Seq. ID No. 1070, Seq. ID No. 1072, Seq. ID No. 1074, Seq. ID No. 1080, Seq. ID No. 1082, Seq. ID No. 1084, Seq. ID No. 1086, Seq. ID No. 1088, Seq. ID No. 1090, Seq. ID No. 1092, Seq. ID No. 1094, Seq. ID No. 1096, Seq. ID No. 1098, Seq. ID No. 1100, Seq. ID No. 1102, Seq. ID No. 1104, Seq. ID No. 1110, Seq. ID No. 1112, Seq. ID No. 1114, Seq. ID No. 1116, Seq. ID No. 1118, Seq. ID No. 1120, Seq. ID No. 1122, Seq. ID No. 1124, Seq. ID No. 1126, Seq. ID No. 1128, Seq. ID No. 1130, Seq. ID No. 1134, Seq. ID No. 1142, Seq. ID No. 1144, Seq. ID No. 1146, Seq. ID No. 1148, Seq. ID No. 1150, Seq. ID No. 1154, Seq. ID No. 1156, Seq. ID No. 1158, Seq. ID No. 1160, Seq. ID No. 1162, Seq. ID No. 1164, Seq. ID No. 1172, Seq. ID No. 1176, Seq. ID No. 1178, Seq. ID No. 1180, Seq. ID No. 1182, Seq. ID No. 1186, Seq. ID No. 1188, Seq. ID No. 1190, Seq. ID No. 1192, Seq. ID No. 1194, Seq. ID No. 1200, Seq. ID No. 1202, Seq. ID No. 1206, Seq. ID No. 1208, Seq. ID No. 1210, Seq. ID No. 1212, Seq. ID No. 1216, Seq. ID No. 1218, Seq. ID No. 1220, Seq. ID No. 1222, Seq. ID No. 1226, Seq. ID No. 1232, Seq. ID No. 1234, Seq. ID No. 1236, Seq. ID No. 1240, Seq. ID No. 1242, Seq. ID No. 1248, Seq. ID No. 1250, Seq. ID No. 1252, Seq. ID No. 1254, Seq. ID No. 1256, Seq. ID No. 1258, Seq. ID No. 1262, Seq. ID No. 1264, Seq. ID No. 1274, Seq. ID No. 1276, Seq. ID No. 1278, Seq. ID No. 1280, Seq. ID No. 1282, Seq. ID No. 1286, Seq. ID No. 1294, Seq. ID No. 1300, Seq. ID No. 1302, Seq. ID No. 1308, Seq. ID No. 1310, Seq. ID No. 1312, Seq. ID No. 1314, Seq. ID No. 1322, Seq. ID No. 1324, Seq. ID No. 1334, Seq. ID No. 1336, Seq. ID No. 1340, Seq. ID No. 1346, Seq. ID No. 1356, Seq. ID No. 1358, Seq. ID No. 1360, Seq. ID No. 1362, Seq. ID No. 1364, Seq. ID No. 1374, Seq. ID No. 1376, Seq. ID No. 1378, Seq. ID No. 1380, Seq. ID No. 1384, Seq. ID No. 1386, Seq. ID No. 1388, Seq. ID No. 1390, Seq. ID No. 1392, Seq. ID No. 1394, Seq. ID No. 1396, Seq. ID No. 1398, Seq. ID No. 1400, Seq. ID No. 1404, Seq. ID No. 1406, Seq. ID No. 1408, Seq. ID No. 1410, Seq. ID No. 1412, Seq. ID No. 1414, Seq. ID No. 1416, Seq. ID No. 1418, Seq. ID No. 1420, Seq. ID No. 1422, Seq. ID No. 1424, Seq. ID No. 1426, Seq. ID No. 1428, Seq. ID No. 1432, Seq. ID No. 1434, Seq. ID No. 1438, Seq. ID No. 1440, Seq. ID No. 1442, Seq. ID No. 1444, Seq. ID No. 1450, Seq. ID No. 1452, Seq. ID No. 1454, Seq. ID No. 1456, Seq. ID No. 1458, Seq. ID No. 1460, Seq. ID No. 1462, Seq. ID No. 1464, Seq. ID No. 1466, Seq. ID No. 1468, Seq. ID No. 1470, Seq. ID No. 1472, Seq. ID No. 1474, Seq. ID No. 1476, Seq. ID No. 1478, Seq. ID No. 1480, Seq. ID No. 1484, Seq. ID No. 1486, Seq. ID No. 1488, Seq. ID No. 1490, Seq. ID No. 1492, Seq. ID No. 1494, Seq. ID No. 1496, Seq. ID No. 1498, Seq. ID No. 1500, Seq. ID No. 1502, Seq. ID No. 1504, Seq. ID No. 1506, Seq. ID No. 1508, Seq. ID No. 1510, Seq. ID No. 1512, Seq. ID No. 1520, Seq. ID No. 1522, Seq. ID No. 1524, Seq. ID No. 1526, Seq. ID No. 1528, Seq. ID No. 1532, Seq. ID No. 1538, Seq. ID No. 1540, Seq. ID No. 1542, Seq. ID No. 1544, Seq. ID No. 1550, Seq. ID No. 1556, Seq. ID No. 1558, Seq. ID No. 1566, Seq. ID No. 1568, Seq. ID No. 1570, Seq. ID No. 1574, Seq. ID No. 1576, Seq. ID No. 1578, Seq. ID No. 1582, Seq. ID No. 1588, Seq. ID No. 1590, Seq. ID No. 1592, Seq. ID No. 1594, Seq. ID No. 1596, Seq. ID No. 1598, Seq. ID No. 1602, Seq. ID No. 1604, Seq. ID No. 1606, Seq. ID No. 1608, Seq. ID No. 1610, Seq. ID No. 1612, Seq. ID No. 1614, Seq. ID No. 1616, Seq. ID No. 1618, Seq. ID No. 1620, Seq. ID No. 1624, Seq. ID No. 1626, Seq. ID No. 1628, Seq. ID No. 1630, Seq. ID No. 1632, Seq. ID No. 1636, Seq. ID No. 1638, Seq. ID No. 1642, Seq. ID No. 1652, Seq. ID No. 1656, Seq. ID No. 1658, Seq. ID No. 1660, Seq. ID No. 1668, Seq. ID No. 1670, Seq. ID No. 1676, Seq. ID No. 1684, Seq. ID No. 1686, Seq. ID No. 1688, Seq. ID No. 1690, Seq. ID No. 1692, Seq. ID No. 1696, Seq. ID No. 1698, Seq. ID No. 1700, Seq. ID No. 1702, Seq. ID No. 1704, Seq. ID No. 1706, Seq. ID No. 1710, Seq. ID No. 1714, Seq. ID No. 1716, Seq. ID No. 1718, Seq. ID No. 1720, Seq. ID No. 1722, Seq. ID No. 1724, Seq. ID No. 1726, Seq. ID No. 1728, Seq. ID No. 1730, Seq. ID No. 1736, Seq. ID No. 1740, Seq. ID No. 1742, Seq. ID No. 1744, Seq. ID No. 1746, Seq. ID No. 1748, Seq. ID No. 1750, Seq. ID No. 1752, Seq. ID No. 1760, Seq. ID No. 1762, Seq. ID No. 1764, Seq. ID No. 1770, Seq. ID No. 1774, Seq. ID No. 1776, Seq. ID No. 1778, Seq. ID No. 1780, Seq. ID No. 1784, Seq. ID No. 1786, Seq. ID No. 1790, Seq. ID No. 1794, Seq. ID No. 1796, Seq. ID No. 1800, Seq. ID No. 1802, Seq. ID No. 1804, Seq. ID No. 1808, Seq. ID No. 1810, Seq. ID No. 1812, Seq. ID No. 1814, Seq. ID No. 1816, Seq. ID No. 1818, Seq. ID No. 1826, Seq. ID No. 1828, Seq. ID No. 1830, Seq. ID No. 1832, Seq. ID No. 1834, Seq. ID No. 1836, Seq. ID No. 1838, Seq. ID No. 1842, Seq. ID No. 1844, Seq. ID No. 1846, Seq. ID No. 1848, Seq. ID No. 1850, Seq. ID No. 1852, Seq. ID No. 1854, Seq. ID No. 1856, Seq. ID No. 1860, Seq. ID No. 1862, Seq. ID No. 1864, Seq. ID No. 1866, Seq. ID No. 1868, Seq. ID No. 1872, Seq. ID No. 1874, Seq. ID No. 1878, Seq. ID No. 1880, Seq. ID No. 1882, Seq. ID No. 1884, Seq. ID No. 1886, Seq. ID No. 1888, Seq. ID No. 1890, Seq. ID No. 1898, Seq. ID No. 1900, Seq. ID No. 1902, Seq. ID No. 1904, Seq. ID No. 1906, Seq. ID No. 1908, Seq. ID No. 1910, Seq. ID No. 1912, Seq. ID No. 1914, Seq. ID No. 1922, Seq. ID No. 1926, Seq. ID No. 1932, Seq. ID No. 1934, Seq. ID No. 1936, Seq. ID No. 1938, Seq. ID No. 1940, Seq. ID No. 1942, Seq. ID No. 1944, Seq. ID No. 1946, Seq. ID No. 1948, Seq. ID No. 1950, Seq. ID No. 1952, Seq. ID No. 1954, Seq. ID No. 1956, Seq. ID No. 1958, Seq. ID No. 1960, Seq. ID No. 1962, Seq. ID No. 1964, Seq. ID No. 1966, Seq. ID No. 1968, Seq. ID No. 1972, Seq. ID No. 1974, Seq. ID No. 1976, Seq. ID No. 1978, Seq. ID No. 1980, Seq. ID No. 1984, Seq. ID No. 1986, Seq. ID No. 1988, Seq. ID No. 1990, Seq. ID No. 1996, Seq. ID No. 1998, Seq. ID No. 2000, Seq. ID No. 2002, Seq. ID No. 2004, Seq. ID No. 2008, Seq. ID No. 2010, Seq. ID No. 2012, Seq. ID No. 2016, Seq. ID No. 2022, Seq. ID No. 2024, Seq. ID No. 2030, Seq. ID No. 2032, Seq. ID No. 2038, Seq. ID No. 2040, Seq. ID No. 2044, Seq. ID No. 2046, Seq. ID No. 2048, Seq. ID No. 2052, Seq. ID No. 2058, Seq. ID No. 2060, Seq. ID No. 2062, Seq. ID No. 2064, Seq. ID No. 2066, Seq. ID No. 2068, Seq. ID No. 2070, Seq. ID No. 2072, Seq. ID No. 2074, Seq. ID No. 2076, Seq. ID No. 2078, Seq. ID No. 2080, Seq. ID No. 2082, Seq. ID No. 2084, Seq. ID No. 2086, Seq. ID No. 2094, Seq. ID No. 2096, Seq. ID No. 2098, Seq. ID No. 2100, Seq. ID No. 2102, Seq. ID No. 2104, Seq. ID No. 2112, Seq. ID No. 2118, Seq. ID No. 2120, Seq. ID No. 2130, Seq. ID No. 2132, Seq. ID No. 2134, Seq. ID No. 2136, Seq. ID No. 2138, Seq. ID No. 2140, Seq. ID No. 2142, Seq. ID No. 2144, Seq. ID No. 2146, Seq. ID No. 2148, Seq. ID No. 2154, Seq. ID No. 2162, Seq. ID No. 2164, Seq. ID No. 2166, Seq. ID No. 2168, Seq. ID No. 2170, Seq. ID No. 2176, Seq. ID No. 2180, Seq. ID No. 2182, Seq. ID No. 2184, Seq. ID No. 2186, Seq. ID No. 2190, Seq. ID No. 2194, Seq. ID No. 2196, Seq. ID No. 2198, Seq. ID No. 2200, Seq. ID No. 2202, Seq. ID No. 2204, Seq. ID No. 2208, Seq. ID No. 2210, Seq. ID No. 2212, Seq. ID No. 2214, Seq. ID No. 2216, Seq. ID No. 2218, Seq. ID No. 2220, Seq. ID No. 2222, Seq. ID No. 2224, Seq. ID No. 2226, Seq. ID No. 2228, Seq. ID No. 2230, Seq. ID No. 2232, Seq. ID No. 2234, Seq. ID No. 2236, Seq. ID No. 2242, Seq. ID No. 2244, Seq. ID No. 2248, Seq. ID No. 2254, Seq. ID No. 2258, Seq. ID No. 2262, Seq. ID No. 2264, Seq. ID No. 2266, Seq. ID No. 2268, Seq. ID No. 2270, Seq. ID No. 2274, Seq. ID No. 2276, Seq. ID No. 2278, Seq. ID No. 2280, Seq. ID No. 2282, Seq. ID No. 2286, Seq. ID No. 2288, Seq. ID No. 2298, Seq. ID No. 2300, Seq. ID No. 2302, Seq. ID No. 2310, Seq. ID No. 2312, Seq. ID No. 2314, Seq. ID No. 2316, Seq. ID No. 2332, Seq. ID No. 2336, Seq. ID No. 2338, Seq. ID No. 2340, Seq. ID No. 2342, Seq. ID No. 2346, Seq. ID No. 2360, Seq. ID No. 2362, Seq. ID No. 2364, Seq. ID No. 2370, Seq. ID No. 2374, Seq. ID No. 2378, Seq. ID No. 2380, Seq. ID No. 2382, Seq. ID No. 2384, Seq. ID No. 2386, Seq. ID No. 2396, Seq. ID No. 2398, Seq. ID No. 2400, Seq. ID No. 2402, Seq. ID No. 2404, Seq. ID No. 2406, Seq. ID No. 2410, Seq. ID No. 2412, Seq. ID No. 2414, Seq. ID No. 2416, Seq. ID No. 2418, Seq. ID No. 2424, Seq. ID No. 2432, Seq. ID No. 2436, Seq. ID No. 2438, Seq. ID No. 2440, Seq. ID No. 2442, Seq. ID No. 2444, Seq. ID No. 2446, Seq. ID No. 2448, Seq. ID No. 2452, Seq. ID No. 2454, Seq. ID No. 2456, Seq. ID No. 2458, Seq. ID No. 2462, Seq. ID No. 2464, Seq. ID No. 2466, Seq. ID No. 2468, Seq. ID No. 2470, Seq. ID No. 2472, Seq. ID No. 2474, Seq. ID No. 2476, Seq. ID No. 2478, Seq. ID No. 2480, Seq. ID No. 2482, Seq. ID No. 2484, Seq. ID No. 2486, Seq. ID No. 2496, Seq. ID No. 2506, Seq. ID No. 2510, Seq. ID No. 2512, Seq. ID No. 2514, Seq. ID No. 2520, Seq. ID No. 2522, Seq. ID No. 2530, Seq. ID No. 2540, Seq. ID No. 2548, Seq. ID No. 2550, Seq. ID No. 2552, Seq. ID No. 2554, Seq. ID No. 2560, Seq. ID No. 2562, Seq. ID No. 2564, Seq. ID No. 2568, Seq. ID No. 2574, Seq. ID No. 2576, Seq. ID No. 2578, Seq. ID No. 2580, Seq. ID No. 2582, Seq. ID No. 2586, Seq. ID No. 2588, Seq. ID No. 2590, Seq. ID No. 2594, Seq. ID No. 2596, Seq. ID No. 2604, Seq. ID No. 2606, Seq. ID No. 2610, Seq. ID No. 2614, Seq. ID No. 2616, Seq. ID No. 2618, Seq. ID No. 2620, Seq. ID No. 2624, Seq. ID No. 2626, Seq. ID No. 2632, Seq. ID No. 2634, Seq. ID No. 2636, Seq. ID No. 2638, Seq. ID No. 2640, Seq. ID No. 2642, Seq. ID No. 2644, Seq. ID No. 2646, Seq. ID No. 2648, Seq. ID No. 2650, Seq. ID No. 2654, Seq. ID No. 2656, Seq. ID No. 2658, Seq. ID No. 2660, Seq. ID No. 2662, Seq. ID No. 2664, Seq. ID No. 2666, Seq. ID No. 2668, Seq. ID No. 2670, Seq. ID No. 2672, Seq. ID No. 2674, Seq. ID No. 2676, Seq. ID No. 2678, Seq. ID No. 2686, Seq. ID No. 2688, Seq. ID No. 2690, Seq. ID No. 2710, Seq. ID No. 2712, Seq. ID No. 2714, Seq. ID No. 2716, Seq. ID No. 2720, Seq. ID No. 2722, Seq. ID No. 2724, Seq. ID No. 2726, Seq. ID No. 2728, Seq. ID No. 2736, Seq. ID No. 2738, Seq. ID No. 2740, Seq. ID No. 2742, Seq. ID No. 2744, Seq. ID No. 2746, Seq. ID No. 2748, Seq. ID No. 2750, Seq. ID No. 2752, Seq. ID No. 2754, Seq. ID No. 2756, Seq. ID No. 2758, Seq. ID No. 2760, Seq. ID No. 2762, Seq. ID No. 2764, Seq. ID No. 2766, Seq. ID No. 2768, Seq. ID No. 2770, Seq. ID No. 2772, Seq. ID No. 2774, Seq. ID No. 2776, Seq. ID No. 2778, Seq. ID No. 2780, Seq. ID No. 2782, Seq. ID No. 2788, Seq. ID No. 2790, Seq. ID No. 2792, Seq. ID No. 2794, Seq. ID No. 2796, Seq. ID No. 2798, Seq. ID No. 2800, Seq. ID No. 2804, Seq. ID No. 2806, Seq. ID No. 2808, Seq. ID No. 2812, Seq. ID No. 2818, Seq. ID No. 2826, Seq. ID No. 2828, Seq. ID No. 2830, Seq. ID No. 2844, Seq. ID No. 2848, Seq. ID No. 2850, Seq. ID No. 2852, Seq. ID No. 2858, Seq. ID No. 2864, Seq. ID No. 2866, Seq. ID No. 2868, Seq. ID No. 2870, Seq. ID No. 2872, Seq. ID No. 2876, Seq. ID No. 2878, Seq. ID No. 2880, Seq. ID No. 2884, Seq. ID No. 2886, Seq. ID No. 2888, Seq. ID No. 2890, Seq. ID No. 2892, Seq. ID No. 2896, Seq. 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ID No. 4980, Seq. ID No. 4982, Seq. ID No. 4984, Seq. ID No. 4986, Seq. ID No. 4990, Seq. ID No. 4992, Seq. ID No. 4994, Seq. ID No. 4996, Seq. ID No. 4998, Seq. ID No. 5002, Seq. ID No. 5004, Seq. ID No. 5006, Seq. ID No. 5008, Seq. ID No. 5010, Seq. ID No. 5012, Seq. ID No. 5016, Seq. ID No. 5018, Seq. ID No. 5020, Seq. ID No. 5022, Seq. ID No. 5024, Seq. ID No. 5026, Seq. ID No. 5028, Seq. ID No. 5030, Seq. ID No. 5034, Seq. ID No. 5036, Seq. ID No. 5038, Seq. ID No. 5040, Seq. ID No. 5042, Seq. ID No. 5044, Seq. ID No. 5046, Seq. ID No. 5048, Seq. ID No. 5050, Seq. ID No. 5052, Seq. ID No. 5054, Seq. ID No. 5056, Seq. ID No. 5058, Seq. ID No. 5060, Seq. ID No. 5066, Seq. ID No. 5068, Seq. ID No. 5072, Seq. ID No. 5074, Seq. ID No. 5076, Seq. ID No. 5078, Seq. ID No. 5080, Seq. ID No. 5082, Seq. ID No. 5084, Seq. ID No. 5088, Seq. ID No. 5090, Seq. ID No. 5092, Seq. ID No. 5094, Seq. ID No. 5096, Seq. ID No. 5098, Seq. ID No. 5100, Seq. ID No. 5102, Seq. ID No. 5106, Seq. ID No. 5108, Seq. ID No. 5110, Seq. ID No. 5112, Seq. ID No. 5114, Seq. ID No. 5118, Seq. ID No. 5120, Seq. ID No. 5122, Seq. ID No. 5128, Seq. ID No. 5144, Seq. ID No. 5146, Seq. ID No. 5148, Seq. ID No. 5150, Seq. ID No. 5152, Seq. ID No. 5154, Seq. ID No. 5156, Seq. ID No. 5158, Seq. ID No. 5162, Seq. ID No. 5164, Seq. ID No. 5168, Seq. ID No. 5170, Seq. ID No. 5172, Seq. ID No. 5174, Seq. ID No. 5178, Seq. ID No. 5180, Seq. ID No. 5182, Seq. ID No. 5184, Seq. ID No. 5186, Seq. ID No. 5188, Seq. ID No. 5190, Seq. ID No. 5192, Seq. ID No. 5194, Seq. ID No. 5196, Seq. ID No. 5202, Seq. ID No. 5204, Seq. ID No. 5210, Seq. ID No. 5212, Seq. ID No. 5216, Seq. ID No. 5218, Seq. ID No. 5222, Seq. ID No. 5226, Seq. ID No. 5228, Seq. ID No. 5230, Seq. ID No. 5232, Seq. ID No. 5234, Seq. ID No. 5236, Seq. ID No. 5238, Seq. ID No. 5240, Seq. ID No. 5242, Seq. ID No. 5244, Seq. ID No. 5246, Seq. ID No. 5248, Seq. ID No. 5250, Seq. ID No. 5252, Seq. ID No. 5254, Seq. ID No. 5256, Seq. ID No. 5258, Seq. ID No. 5260, Seq. ID No. 5262, Seq. ID No. 5264, Seq. ID No. 5266, Seq. ID No. 5270, Seq. ID No. 5272, Seq. ID No. 5284, Seq. ID No. 5288, Seq. ID No. 5290, Seq. ID No. 5292, Seq. ID No. 5294, Seq. ID No. 5296, Seq. ID No. 5298, Seq. ID No. 5300, Seq. ID No. 5302, Seq. ID No. 5304, Seq. ID No. 5306, Seq. ID No. 5308, Seq. ID No. 5310, Seq. ID No. 5312, Seq. ID No. 5314, Seq. ID No. 5316, Seq. ID No. 5318, Seq. ID No. 5320, Seq. ID No. 5322, Seq. ID No. 5324, Seq. ID No. 5326, Seq. ID No. 5334, Seq. ID No. 5336, Seq. ID No. 5338, Seq. ID No. 5340, Seq. ID No. 5344, Seq. ID No. 5346, Seq. ID No. 5348, Seq. ID No. 5350, Seq. ID No. 5352, Seq. ID No. 5354, Seq. ID No. 5356, Seq. ID No. 5358, Seq. ID No. 5360, Seq. ID No. 5362, Seq. ID No. 5364, Seq. ID No. 5366, Seq. ID No. 5368, Seq. ID No. 5370, Seq. ID No. 5372, Seq. ID No. 5374, Seq. ID No. 5376, Seq. ID No. 5382, Seq. ID No. 5384, Seq. ID No. 5390, Seq. ID No. 5392, Seq. ID No. 5394, Seq. ID No. 5396, Seq. ID No. 5398, Seq. ID No. 5400, Seq. ID No. 5402, Seq. ID No. 5404, Seq. ID No. 5408, Seq. ID No. 5410, Seq. ID No. 5412, Seq. ID No. 5418, Seq. ID No. 5420, Seq. ID No. 5422, Seq. ID No. 5424, Seq. ID No. 5426, Seq. ID No. 5428, Seq. ID No. 5430, Seq. ID No. 5432, Seq. ID No. 5436, Seq. ID No. 5438, Seq. ID No. 5440, Seq. ID No. 5442, Seq. ID No. 5444, Seq. ID No. 5446, Seq. ID No. 5448, Seq. ID No. 5450, Seq. ID No. 5452, Seq. ID No. 5456, Seq. ID No. 5458, Seq. ID No. 5468, Seq. ID No. 5470, Seq. ID No. 5472, Seq. ID No. 5474, Seq. ID No. 5476, Seq. ID No. 5478, Seq. ID No. 5480, Seq. ID No. 5482, Seq. ID No. 5484, Seq. ID No. 5486, Seq. ID No. 5488, Seq. ID No. 5490, Seq. ID No. 5494, Seq. ID No. 5496, Seq. ID No. 5500, Seq. ID No. 5502, Seq. ID No. 5504, Seq. ID No. 5506, Seq. ID No. 5508, Seq. ID No. 5512, Seq. ID No. 5520, Seq. ID No. 5522, Seq. ID No. 5524, Seq. ID No. 5528, Seq. ID No. 5536, Seq. ID No. 5538, Seq. ID No. 5540, Seq. ID No. 5542, Seq. ID No. 5548, Seq. ID No. 5550, Seq. ID No. 5552, Seq. ID No. 5554, Seq. ID No. 5556, Seq. ID No. 5558, Seq. ID No. 5560, Seq. ID No. 5562, Seq. ID No. 5564, Seq. ID No. 5566, Seq. ID No. 5568, Seq. ID No. 5572, Seq. ID No. 5574, Seq. ID No. 5576, Seq. ID No. 5578, Seq. ID No. 5580, Seq. ID No. 5582, Seq. ID No. 5584, Seq. ID No. 5586, Seq. ID No. 5600, Seq. ID No. 5602, Seq. ID No. 5604, Seq. ID No. 5606, Seq. ID No. 5608, Seq. ID No. 5614, Seq. ID No. 5616, Seq. ID No. 5618, Seq. ID No. 5620, Seq. ID No. 5628, Seq. ID No. 5630, Seq. ID No. 5632, Seq. ID No. 5636, Seq. ID No. 5646, Seq. ID No. 5648, Seq. ID No. 5652, Seq. ID No. 5654, Seq. ID No. 5656, Seq. ID No. 5658, Seq. ID No. 5662, Seq. ID No. 5664, Seq. ID No. 5666, Seq. ID No. 5670, Seq. ID No. 5672, Seq. ID No. 5674, Seq. ID No. 5676, Seq. ID No. 5678, Seq. ID No. 5680, Seq. ID No. 5692, Seq. ID No. 5694, Seq. ID No. 5696, Seq. ID No. 5698, Seq. ID No. 5702, Seq. ID No. 5708, Seq. ID No. 5714, Seq. ID No. 5716, Seq. ID No. 5718, Seq. ID No. 5722, Seq. ID No. 5724, Seq. ID No. 5726, Seq. ID No. 5728, Seq. ID No. 5732, Seq. ID No. 5738, Seq. ID No. 5742, Seq. ID No. 5744, Seq. ID No. 5746, Seq. ID No. 5748, Seq. ID No. 5750, Seq. ID No. 5752, Seq. ID No. 5754, Seq. ID No. 5756, Seq. ID No. 5758, Seq. ID No. 5760, Seq. ID No. 5762, Seq. ID No. 5770, Seq. ID No. 5774, Seq. ID No. 5776, Seq. ID No. 5778, Seq. ID No. 5780, Seq. ID No. 5782, Seq. ID No. 5788, Seq. ID No. 5790, Seq. ID No. 5794, Seq. ID No. 5796, Seq. ID No. 5800, Seq. ID No. 5802, Seq. ID No. 5804, Seq. ID No. 5806, Seq. ID No. 5808, Seq. ID No. 5810, Seq. ID No. 5812, Seq. ID No. 5814, Seq. ID No. 5816, Seq. ID No. 5818, Seq. ID No. 5820, Seq. ID No. 5822, Seq. ID No. 5824, Seq. ID No. 5826, Seq. ID No. 5828, Seq. ID No. 5832, Seq. ID No. 5834, Seq. ID No. 5836, Seq. ID No. 5838, Seq. ID No. 5840, Seq. ID No. 5842, Seq. ID No. 5844, Seq. ID No. 5846, Seq. ID No. 5848, Seq. ID No. 5850, Seq. ID No. 5852, Seq. ID No. 5854, Seq. ID No. 5856, Seq. ID No. 5858, Seq. ID No. 5860, Seq. ID No. 5862, Seq. ID No. 5864, Seq. ID No. 5866, Seq. ID No. 5868, Seq. ID No. 5870, Seq. ID No. 5872, Seq. ID No. 5874, Seq. ID No. 5876, Seq. ID No. 5878, Seq. ID No. 5882, Seq. ID No. 5888, Seq. ID No. 5892, Seq. ID No. 5898, Seq. ID No. 5904, Seq. ID No. 5908, Seq. ID No. 5912, Seq. ID No. 5914, Seq. ID No. 5916, Seq. ID No. 5918, Seq. ID No. 5920, Seq. ID No. 5926, Seq. ID No. 5932, Seq. ID No. 5934, Seq. ID No. 5936, Seq. ID No. 5938, Seq. ID No. 5942, Seq. ID No. 5944, Seq. ID No. 5946, Seq. ID No. 5948, Seq. ID No. 5950, Seq. ID No. 5952, Seq. ID No. 5954, Seq. ID No. 5956, Seq. ID No. 5958, Seq. ID No. 5960, Seq. ID No. 5962, Seq. ID No. 5964, Seq. ID No. 5966, Seq. ID No. 5968, Seq. ID No. 5970, Seq. ID No. 5972, Seq. ID No. 5974, Seq. ID No. 5976, Seq. ID No. 5978, Seq. ID No. 5980, Seq. ID No. 5982, Seq. ID No. 5984, Seq. ID No. 5986, Seq. ID No. 5988, Seq. ID No. 5990, Seq. ID No. 5992, Seq. ID No. 5994, Seq. ID No. 5996, Seq. ID No. 5998, Seq. ID No. 6000, Seq. ID No. 6002, Seq. ID No. 6004, Seq. ID No. 6006, Seq. ID No. 6008, Seq. ID No. 6010, Seq. ID No. 6012, Seq. ID No. 6014, Seq. ID No. 6016, Seq. ID No. 6018, Seq. ID No. 6020, Seq. ID No. 6022, Seq. ID No. 6030, Seq. ID No. 6032, Seq. ID No. 6034, Seq. ID No. 6036, Seq. ID No. 6038, Seq. ID No. 6040, Seq. ID No. 6042, Seq. ID No. 6046, Seq. ID No. 6050, Seq. ID No. 6052, Seq. ID No. 6056, Seq. ID No. 6058, Seq. ID No. 6062, Seq. ID No. 6066, Seq. ID No. 6070, Seq. ID No. 6072, Seq. ID No. 6074, Seq. ID No. 6076, Seq. ID No. 6078, Seq. ID No. 6080, Seq. ID No. 6082, Seq. ID No. 6084, Seq. ID No. 6086, Seq. ID No. 6094, Seq. ID No. 6098, Seq. ID No. 6100, Seq. ID No. 6102, Seq. ID No. 6106, Seq. ID No. 6114, Seq. ID No. 6120, Seq. ID No. 6122, Seq. ID No. 6124, Seq. ID No. 6126, Seq. ID No. 6128, Seq. ID No. 6130, Seq. ID No. 6132, Seq. ID No. 6134, Seq. ID No. 6140, Seq. ID No. 6142, Seq. ID No. 6144, Seq. ID No. 6146, Seq. ID No. 6148, Seq. ID No. 6150, Seq. ID No. 6152, Seq. ID No. 6154, Seq. ID No. 6156, Seq. ID No. 6158, Seq. ID No. 6168, Seq. ID No. 6172, Seq. ID No. 6174, Seq. ID No. 6176, Seq. ID No. 6178, Seq. ID No. 6180, Seq. ID No. 6182, Seq. ID No. 6194, Seq. ID No. 6196, Seq. ID No. 6200, Seq. ID No. 6202, Seq. ID No. 6208, Seq. ID No. 6212, Seq. ID No. 6214, Seq. ID No. 6216, Seq. ID No. 6220, Seq. ID No. 6232, Seq. ID No. 6234, Seq. ID No. 6240, Seq. ID No. 6248, Seq. ID No. 6252, Seq. ID No. 6256, Seq. ID No. 6258, Seq. ID No. 6262, Seq. ID No. 6270, Seq. ID No. 6272, Seq. ID No. 6278, Seq. ID No. 6280, Seq. ID No. 6282, Seq. ID No. 6288, Seq. ID No. 6292, Seq. ID No. 6294, Seq. ID No. 6296, Seq. ID No. 6298, Seq. ID No. 6300, Seq. ID No. 6306, Seq. ID No. 6308, Seq. ID No. 6310, Seq. ID No. 6312, Seq. ID No. 6314, Seq. ID No. 6316, Seq. ID No. 6318, Seq. ID No. 6320, Seq. ID No. 6322, Seq. ID No. 6324, Seq. ID No. 6330, Seq. ID No. 6332, Seq. ID No. 6334, Seq. ID No. 6336, Seq. ID No. 6338, Seq. ID No. 6340, Seq. ID No. 6342, Seq. ID No. 6344, Seq. ID No. 6346, Seq. ID No. 6348, Seq. ID No. 6350, Seq. ID No. 6352, Seq. ID No. 6354, Seq. ID No. 6356, Seq. ID No. 6358, Seq. ID No. 6360, Seq. ID No. 6362, Seq. ID No. 6368, Seq. ID No. 6370, Seq. ID No. 6372, Seq. ID No. 6374, Seq. ID No. 6376, Seq. ID No. 6380, Seq. ID No. 6386, Seq. ID No. 6388, Seq. ID No. 6390, Seq. ID No. 6392, Seq. ID No. 6394, Seq. ID No. 6396, Seq. ID No. 6398, Seq. ID No. 6400, Seq. ID No. 6402, Seq. ID No. 6404, Seq. ID No. 6406, Seq. ID No. 6408, Seq. ID No. 6410, Seq. ID No. 6412, Seq. ID No. 6414, Seq. ID No. 6418, Seq. ID No. 6420, Seq. ID No. 6422, Seq. ID No. 6424, Seq. ID No. 6434, Seq. ID No. 6436, Seq. ID No. 6438, Seq. ID No. 6440, Seq. ID No. 6442, Seq. ID No. 6444, Seq. ID No. 6446, Seq. ID No. 6448, Seq. ID No. 6450, Seq. ID No. 6452, Seq. ID No. 6454, Seq. ID No. 6456, Seq. ID No. 6458, Seq. ID No. 6460, Seq. ID No. 6462, Seq. ID No. 6464, Seq. ID No. 6466, Seq. ID No. 6468, Seq. ID No. 6470, Seq. ID No. 6472, Seq. ID No. 6476, Seq. ID No. 6478, Seq. ID No. 6482, Seq. ID No. 6484, Seq. ID No. 6486, Seq. ID No. 6488, Seq. ID No. 6490, Seq. ID No. 6492, Seq. ID No. 6494, Seq. ID No. 6496, Seq. ID No. 6500, Seq. ID No. 6502, Seq. ID No. 6504, Seq. ID No. 6506, Seq. ID No. 6508, Seq. ID No. 6510, Seq. ID No. 6512, Seq. ID No. 6514, Seq. ID No. 6516, Seq. ID No. 6520, Seq. ID No. 6522, Seq. ID No. 6524, Seq. ID No. 6526, Seq. ID No. 6528, Seq. ID No. 6530, Seq. ID No. 6532, Seq. ID No. 6534, Seq. ID No. 6536, Seq. ID No. 6538, Seq. ID No. 6540, Seq. ID No. 6546, Seq. ID No. 6548, Seq. ID No. 6550, Seq. ID No. 6552, Seq. ID No. 6554, Seq. ID No. 6560, Seq. ID No. 6562, Seq. ID No. 6564, Seq. ID No. 6566, Seq. ID No. 6568, Seq. ID No. 6570, Seq. ID No. 6576, Seq. ID No. 6578, Seq. ID No. 6580, Seq. ID No. 6584, Seq. ID No. 6586, Seq. ID No. 6588, Seq. ID No. 6590, Seq. ID No. 6592, Seq. ID No. 6606, Seq. ID No. 6608, Seq. ID No. 6610, Seq. ID No. 6612, Seq. ID No. 6614, Seq. ID No. 6616, Seq. ID No. 6618, Seq. ID No. 6620, Seq. ID No. 6622, Seq. ID No. 6624, Seq. ID No. 6626, Seq. ID No. 6628, Seq. ID No. 6630, Seq. ID No. 6634, Seq. ID No. 6636, Seq. ID No. 6642, and Seq. ID No.
 6648. 41. The Alloiococcus otitidis polypeptide of claim 36, wherein the polypeptide is identified by BlastP analysis, and is selected from one of Seq. ID No. 10, Seq. ID No. 18, Seq. ID No. 46, Seq. ID No. 50, Seq. ID No. 54, Seq. ID No. 60, Seq. ID No. 90, Seq. ID No. 146, Seq. ID No. 158, Seq. ID No. 168, Seq. ID No. 172, Seq. ID No. 192, Seq. ID No. 216, Seq. ID No. 218, Seq. ID No. 226, Seq. ID No. 240, Seq. ID No. 254, Seq. ID No. 274, Seq. ID No. 278, Seq. ID No. 290, Seq. ID No. 330, Seq. ID No. 344, Seq. ID No. 346, Seq. ID No. 376, Seq. ID No. 502, Seq. ID No. 506, Seq. ID No. 512, Seq. ID No. 516, Seq. ID No. 530, Seq. ID No. 570, Seq. ID No. 576, Seq. ID No. 594, Seq. ID No. 596, Seq. ID No. 638, Seq. ID No. 660, Seq. ID No. 670, Seq. ID No. 676, Seq. ID No. 682, Seq. ID No. 730, Seq. ID No. 780, Seq. ID No. 820, Seq. ID No. 896, Seq. ID No. 922, Seq. ID No. 936, Seq. ID No. 956, Seq. ID No. 968, Seq. ID No. 986, Seq. ID No. 1018, Seq. ID No. 1040, Seq. ID No. 1076, Seq. ID No. 1090, Seq. ID No. 1138, Seq. ID No. 1224, Seq. ID No. 1242, Seq. ID No. 1316, Seq. ID No. 1332, Seq. ID No. 1370, Seq. ID No. 1460, Seq. ID No. 1518, Seq. ID No. 1562, Seq. ID No. 1564, Seq. ID No. 1568, Seq. ID No. 1572, Seq. ID No. 1574, Seq. ID No. 1602, Seq. ID No. 1608, Seq. ID No. 1614, Seq. ID No. 1620, Seq. ID No. 1642, Seq. ID No. 1648, Seq. ID No. 1654, Seq. ID No. 1658, Seq. ID No. 1666, Seq. ID No. 1700, Seq. ID No. 1714, Seq. ID No. 1752, Seq. ID No. 1772, Seq. ID No. 1786, Seq. ID No. 1790, Seq. ID No. 1792, Seq. ID No. 1798, Seq. ID No. 1812, Seq. ID No. 1818, Seq. ID No. 1820, Seq. ID No. 1822, Seq. ID No. 1872, Seq. ID No. 1896, Seq. ID No. 1906, Seq. ID No. 1914, Seq. ID No. 1920, Seq. ID No. 1924, Seq. ID No. 1966, Seq. ID No. 1972, Seq. ID No. 2000, Seq. ID No. 2048, Seq. ID No. 2056, Seq. ID No. 2092, Seq. ID No. 2094, Seq. ID No. 2116, Seq. ID No. 2120, Seq. ID No. 2128, Seq. ID No. 2166, Seq. ID No. 2180, Seq. ID No. 2208, Seq. ID No. 2224, Seq. ID No. 2228, Seq. ID No. 2242, Seq. ID No. 2254, Seq. ID No. 2264, Seq. ID No. 2270, Seq. ID No. 2276, Seq. ID No. 2302, Seq. ID No. 2316, Seq. ID No. 2330, Seq. ID No. 2334, Seq. ID No. 2344, Seq. ID No. 2346, Seq. ID No. 2364, Seq. ID No. 2374, Seq. ID No. 2392, Seq. ID No. 2418, Seq. ID No. 2430, Seq. ID No. 2466, Seq. ID No. 2476, Seq. ID No. 2484, Seq. ID No. 2514, Seq. ID No. 2526, Seq. ID No. 2590, Seq. ID No. 2614, Seq. ID No. 2652, Seq. ID No. 2670, Seq. ID No. 2678, Seq. ID No. 2688, Seq. ID No. 2690, Seq. ID No. 2694, Seq. ID No. 2704, Seq. ID No. 2710, Seq. ID No. 2716, Seq. ID No. 2752, Seq. ID No. 2754, Seq. ID No. 2768, Seq. ID No. 2788, Seq. ID No. 2792, Seq. ID No. 2804, Seq. ID No. 2868, Seq. ID No. 2872, Seq. ID No. 2908, Seq. ID No. 2920, Seq. ID No. 2922, Seq. ID No. 2924, Seq. ID No. 2928, Seq. ID No. 2934, Seq. ID No. 2958, Seq. ID No. 2980, Seq. ID No. 3000, Seq. ID No. 3006, Seq. ID No. 3020, Seq. ID No. 3032, Seq. ID No. 3036, Seq. ID No. 3056, Seq. ID No. 3068, Seq. ID No. 3086, Seq. ID No. 3166, Seq. ID No. 3184, Seq. ID No. 3190, Seq. ID No. 3198, Seq. ID No. 3212, Seq. ID No. 3252, Seq. ID No. 3258, Seq. ID No. 3260, Seq. ID No. 3298, Seq. ID No. 3320, Seq. ID No. 3324, Seq. ID No. 3336, Seq. ID No. 3338, Seq. ID No. 3356, Seq. ID No. 3360, Seq. ID No. 3378, Seq. ID No. 3398, Seq. ID No. 3406, Seq. ID No. 3416, Seq. ID No. 3426, Seq. ID No. 3428, Seq. ID No. 3462, Seq. ID No. 3464, Seq. ID No. 3488, Seq. ID No. 3494, Seq. ID No. 3498, Seq. ID No. 3508, Seq. ID No. 3520, Seq. ID No. 3522, Seq. ID No. 3530, Seq. ID No. 3536, Seq. ID No. 3630, Seq. ID No. 3636, Seq. ID No. 3728, Seq. ID No. 3760, Seq. ID No. 3772, Seq. ID No. 3794, Seq. ID No. 3840, Seq. ID No. 3852, Seq. ID No. 3864, Seq. ID No. 3866, Seq. ID No. 3884, Seq. ID No. 3892, Seq. ID No. 3914, Seq. ID No. 3926, Seq. ID No. 3930, Seq. ID No. 3976, Seq. ID No. 3982, Seq. ID No. 4028, Seq. ID No. 4040, Seq. ID No. 4062, Seq. ID No. 4074, Seq. ID No. 4082, Seq. ID No. 4104, Seq. ID No. 4112, Seq. ID No. 4138, Seq. ID No. 4226, Seq. ID No. 4248, Seq. ID No. 4344, Seq. ID No. 4380, Seq. ID No. 4390, Seq. ID No. 4470, Seq. ID No. 4474, Seq. ID No. 4482, Seq. ID No. 4486, Seq. ID No. 4494, Seq. ID No. 4530, Seq. ID No. 4644, Seq. ID No. 4706, Seq. ID No. 4714, Seq. ID No. 4718, Seq. ID No. 4814, Seq. ID No. 4816, Seq. ID No. 4826, Seq. ID No. 4828, Seq. ID No. 4834, Seq. ID No. 4838, Seq. ID No. 4852, Seq. ID No. 4864, Seq. ID No. 4876, Seq. ID No. 4880, Seq. ID No. 4894, Seq. ID No. 4902, Seq. ID No. 4920, Seq. ID No. 4932, Seq. ID No. 4960, Seq. ID No. 4964, Seq. ID No. 4986, Seq. ID No. 5114, Seq. ID No. 5116, Seq. ID No. 5118, Seq. ID No. 5126, Seq. ID No. 5142, Seq. ID No. 5184, Seq. ID No. 5202, Seq. ID No. 5206, Seq. ID No. 5214, Seq. ID No. 5220, Seq. ID No. 5280, Seq. ID No. 5286, Seq. ID No. 5332, Seq. ID No. 5382, Seq. ID No. 5390, Seq. ID No. 5406, Seq. ID No. 5412, Seq. ID No. 5420, Seq. ID No. 5434, Seq. ID No. 5464, Seq. ID No. 5478, Seq. ID No. 5492, Seq. ID No. 5510, Seq. ID No. 5514, Seq. ID No. 5526, Seq. ID No. 5530, Seq. ID No. 5538, Seq. ID No. 5568, Seq. ID No. 5600, Seq. ID No. 5622, Seq. ID No. 5638, Seq. ID No. 5700, Seq. ID No. 5724, Seq. ID No. 5734, Seq. ID No. 5762, Seq. ID No. 5792, Seq. ID No. 5896, Seq. ID No. 5902, Seq. ID No. 5904, Seq. ID No. 5910, Seq. ID No. 5914, Seq. ID No. 5920, Seq. ID No. 5930, Seq. ID No. 5940, Seq. ID No. 6002, Seq. ID No. 6044, Seq. ID No. 6054, Seq. ID No. 6058, Seq. ID No. 6090, Seq. ID No. 6096, Seq. ID No. 6104, Seq. ID No. 6112, Seq. ID No. 6118, Seq. ID No. 6166, Seq. ID No. 6170, Seq. ID No. 6186, Seq. ID No. 6192, Seq. ID No. 6210, Seq. ID No. 6230, Seq. ID No. 6258, Seq. ID No. 6264, Seq. ID No. 6272, Seq. ID No. 6276, Seq. ID No. 6290, Seq. ID No. 6304, Seq. ID No. 6366, Seq. ID No. 6370, Seq. ID No. 6384, and Seq. ID No.
 6416. 42. The Alloiococcus otitidis polypeptide of claim 36, wherein the polypeptide is identified by Pfam analysis, and is selected from one of Seq. ID No. 90, Seq. ID No. 146, Seq. ID No. 156, Seq. ID No. 168, Seq. ID No. 174, Seq. ID No. 192, Seq. ID No. 216, Seq. ID No. 220, Seq. ID No. 222, Seq. ID No. 224, Seq. ID No. 226, Seq. ID No. 234, Seq. ID No. 240, Seq. ID No. 252, Seq. ID No. 254, Seq. ID No. 272, Seq. ID No. 292, Seq. ID No. 332, Seq. ID No. 342, Seq. ID No. 346, Seq. ID No. 376, Seq. ID No. 502, Seq. ID No. 506, Seq. ID No. 512, Seq. ID No. 530, Seq. ID No. 568, Seq. ID No. 570, Seq. ID No. 576, Seq. ID No. 594, Seq. ID No. 596, Seq. ID No. 602, Seq. ID No. 638, Seq. ID No. 650, Seq. ID No. 662, Seq. ID No. 670, Seq. ID No. 676, Seq. ID No. 682, Seq. ID No. 684, Seq. ID No. 730, Seq. ID No. 754, Seq. ID No. 780, Seq. ID No. 828, Seq. ID No. 840, Seq. ID No. 896, Seq. ID No. 940, Seq. ID No. 970, Seq. ID No. 986, Seq. ID No. 1016, Seq. ID No. 1040, Seq. ID No. 1076, Seq. ID No. 1138, Seq. ID No. 1156, Seq. ID No. 1164, Seq. ID No. 1176, Seq. ID No. 1224, Seq. ID No. 1232, Seq. ID No. 1238, Seq. ID No. 1242, Seq. ID No. 1262, Seq. ID No. 1332, Seq. ID No. 1340, Seq. ID No. 1370, Seq. ID No. 1478, Seq. ID No. 1518, Seq. ID No. 1532, Seq. ID No. 1540, Seq. ID No. 1550, Seq. ID No. 1564, Seq. ID No. 1568, Seq. ID No. 1572, Seq. ID No. 1574, Seq. ID No. 1590, Seq. ID No. 1596, Seq. ID No. 1648, Seq. ID No. 1658, Seq. ID No. 1772, Seq. ID No. 1786, Seq. ID No. 1790, Seq. ID No. 1820, Seq. ID No. 1822, Seq. ID No. 1970, Seq. ID No. 2016, Seq. ID No. 2048, Seq. ID No. 2088, Seq. ID No. 2090, Seq. ID No. 2094, Seq. ID No. 2116, Seq. ID No. 2118, Seq. ID No. 2128, Seq. ID No. 2142, Seq. ID No. 2180, Seq. ID No. 2208, Seq. ID No. 2224, Seq. ID No. 2254, Seq. ID No. 2276, Seq. ID No. 2302, Seq. ID No. 2316, Seq. ID No. 2330, Seq. ID No. 2344, Seq. ID No. 2350, Seq. ID No. 2364, Seq. ID No. 2382, Seq. ID No. 2392, Seq. ID No. 2418, Seq. ID No. 2422, Seq. ID No. 2424, Seq. ID No. 2430, Seq. ID No. 2482, Seq. ID No. 2488, Seq. ID No. 2490, Seq. ID No. 2492, Seq. ID No. 2510, Seq. ID No. 2520, Seq. ID No. 2526, Seq. ID No. 2548, Seq. ID No. 2554, Seq. ID No. 2564, Seq. ID No. 2588, Seq. ID No. 2600, Seq. ID No. 2608, Seq. ID No. 2614, Seq. ID No. 2652, Seq. ID No. 2676, Seq. ID No. 2682, Seq. ID No. 2688, Seq. ID No. 2694, Seq. ID No. 2700, Seq. ID No. 2704, Seq. ID No. 2710, Seq. ID No. 2712, Seq. ID No. 2728, Seq. ID No. 2754, Seq. ID No. 2820, Seq. ID No. 2822, Seq. ID No. 2824, Seq. ID No. 2868, Seq. ID No. 2872, Seq. ID No. 2908, Seq. ID No. 2920, Seq. ID No. 2958, Seq. ID No. 2972, Seq. ID No. 2980, Seq. ID No. 3000, Seq. ID No. 3006, Seq. ID No. 3020, Seq. ID No. 3036, Seq. ID No. 3066, Seq. ID No. 3086, Seq. ID No. 3150, Seq. ID No. 3166, Seq. ID No. 3184, Seq. ID No. 3204, Seq. ID No. 3212, Seq. ID No. 3252, Seq. ID No. 3260, Seq. ID No. 3320, Seq. ID No. 3324, Seq. ID No. 3336, Seq. ID No. 3338, Seq. ID No. 3348, Seq. ID No. 3360, Seq. ID No. 3378, Seq. ID No. 3380, Seq. ID No. 3400, Seq. ID No. 3426, Seq. ID No. 3484, Seq. ID No. 3496, Seq. ID No. 3498, Seq. ID No. 3520, Seq. ID No. 3530, Seq. ID No. 3600, Seq. ID No. 3612, Seq. ID No. 3616, Seq. ID No. 3620, Seq. ID No. 3664, Seq. ID No. 3740, Seq. ID No. 3760, Seq. ID No. 3772, Seq. ID No. 3798, Seq. ID No. 3826, Seq. ID No. 3842, Seq. ID No. 3856, Seq. ID No. 3864, Seq. ID No. 3902, Seq. ID No. 3930, Seq. ID No. 4016, Seq. ID No. 4018, Seq. ID No. 4056, Seq. ID No. 4076, Seq. ID No. 4086, Seq. ID No. 4090, Seq. ID No. 4100, Seq. ID No. 4106, Seq. ID No. 4130, Seq. ID No. 4204, Seq. ID No. 4244, Seq. ID No. 4252, Seq. ID No. 4344, Seq. ID No. 4384, Seq. ID No. 4476, Seq. ID No. 4482, Seq. ID No. 4488, Seq. ID No. 4492, Seq. ID No. 4534, Seq. ID No. 4628, Seq. ID No. 4706, Seq. ID No. 4714, Seq. ID No. 4718, Seq. ID No. 4720, Seq. ID No. 4730, Seq. ID No. 4790, Seq. ID No. 4792, Seq. ID No. 4794, Seq. ID No. 4804, Seq. ID No. 4814, Seq. ID No. 4816, Seq. ID No. 4826, Seq. ID No. 4834, Seq. ID No. 4838, Seq. ID No. 4876, Seq. ID No. 4880, Seq. ID No. 4920, Seq. ID No. 4932, Seq. ID No. 4948, Seq. ID No. 4986, Seq. ID No. 5078, Seq. ID No. 5116, Seq. ID No. 5118, Seq. ID No. 5128, Seq. ID No. 5142, Seq. ID No. 5194, Seq. ID No. 5216, Seq. ID No. 5220, Seq. ID No. 5276, Seq. ID No. 5382, Seq. ID No. 5390, Seq. ID No. 5410, Seq. ID No. 5412, Seq. ID No. 5476, Seq. ID No. 5492, Seq. ID No. 5514, Seq. ID No. 5520, Seq. ID No. 5526, Seq. ID No. 5530, Seq. ID No. 5538, Seq. ID No. 5558, Seq. ID No. 5582, Seq. ID No. 5600, Seq. ID No. 5638, Seq. ID No. 5686, Seq. ID No. 5724, Seq. ID No. 5756, Seq. ID No. 5762, Seq. ID No. 5896, Seq. ID No. 5902, Seq. ID No. 5904, Seq. ID No. 5912, Seq. ID No. 5914, Seq. ID No. 5920, Seq. ID No. 5924, Seq. ID No. 5930, Seq. ID No. 6002, Seq. ID No. 6044, Seq. ID No. 6054, Seq. ID No. 6056, Seq. ID No. 6090, Seq. ID No. 6096, Seq. ID No. 6112, Seq. ID No. 6118, Seq. ID No. 6166, Seq. ID No. 6170, Seq. ID No. 6188, Seq. ID No. 6196, Seq. ID No. 6220, Seq. ID No. 6234, Seq. ID No. 6270, Seq. ID No. 6276, Seq. ID No. 6280, Seq. ID No. 6288, Seq. ID No. 6298, Seq. ID No. 6300, Seq. ID No. 6306, Seq. ID No. 6312, Seq. ID No. 6370, Seq. ID No. 6380, Seq. ID No. 6588, and Seq. ID No.
 6592. 43. The Alloiococcus otitidis polypeptide of claim 36, wherein the polypeptide is identified using proteomics methodology as sharing homology with surface exposed proteins of Streptococcus pneumoniae, and is selected from one of Seq. ID No. 2, Seq. ID No. 6, Seq. ID No. 94, Seq. ID No. 96, Seq. ID No. 104, Seq. ID No. 108, Seq. ID No. 158, Seq. ID No. 224, Seq. ID No. 226, Seq. ID No. 234, Seq. ID No. 240, Seq. ID No. 254, Seq. ID No. 318, Seq. ID No. 322, Seq. ID No. 342, Seq. ID No. 346, Seq. ID No. 354, Seq. ID No. 362, Seq. ID No. 364, Seq. ID No. 366, Seq. ID No. 376, Seq. ID No. 380, Seq. ID No. 384, Seq. ID No. 390, Seq. ID No. 392, Seq. ID No. 398, Seq. ID No. 406, Seq. ID No. 410, Seq. ID No. 416, Seq. ID No. 424, Seq. ID No. 426, Seq. ID No. 428, Seq. ID No. 430, Seq. ID No. 436; Seq. ID No. 438, Seq. ID No. 440, Seq. ID No. 442, Seq. ID No. 444, Seq. ID No. 446, Seq. ID No. 448, Seq. ID No. 450, Seq. ID No. 462, Seq. ID No. 464, Seq. ID No. 466, Seq. ID No. 514, Seq. ID No. 544, Seq. ID No. 552, Seq. ID No. 554, Seq. ID No. 560, Seq. ID No. 596, Seq. ID No. 602, Seq. ID No. 638, Seq. ID No. 650, Seq. ID No. 658, Seq. ID No. 670, Seq. ID No. 676, Seq. ID No. 684, Seq. ID No. 754, Seq. ID No. 930, Seq. ID No. 970, Seq. ID No. 1042, Seq. ID No. 1044, Seq. ID No. 1086, Seq. ID No. 1090, Seq. ID No. 1094, Seq. ID No. 1098, Seq. ID No. 1100, Seq. ID No. 1102, Seq. ID No. 1176, Seq. ID No. 1206, Seq. ID No. 1238, Seq. ID No. 1460, Seq. ID No. 1496, Seq. ID No. 1498, Seq. ID No. 1504, Seq. ID No. 1518, Seq. ID No. 1528, Seq. ID No. 1532, Seq. ID No. 1540, Seq. ID No. 1544, Seq. ID No. 1550, Seq. ID No. 1574, Seq. ID No. 1658, Seq. ID No. 1710, Seq. ID No. 1768, Seq. ID No. 1786, Seq. ID No. 1822, Seq. ID No. 1890, Seq. ID No. 1926, Seq. ID No. 1970, Seq. ID No. 2004, Seq. ID No. 2048, Seq. ID No. 2076, Seq. ID No. 2090, Seq. ID No. 2094, Seq. ID No. 2118, Seq. ID No. 2138, Seq. ID No. 2144, Seq. ID No. 2206, Seq. ID No. 2236, Seq. ID No. 2258, Seq. ID No. 2302, Seq. ID No. 2364, Seq. ID No. 2424, Seq. ID No. 2446, Seq. ID No. 2452, Seq. ID No. 2482, Seq. ID No. 2496, Seq. ID No. 2506, Seq. ID No. 2578, Seq. ID No. 2588, Seq. ID No. 2614, Seq. ID No. 2634, Seq. ID No. 2652, Seq. ID No. 2666, Seq. ID No. 2670, Seq. ID No. 2678, Seq. ID No. 2688, Seq. ID No. 2694, Seq. ID No. 2700, Seq. ID No. 2712, Seq. ID No. 2716, Seq. ID No. 2758, Seq. ID No. 2792, Seq. ID No. 2794, Seq. ID No. 2804, Seq. ID No. 2868, Seq. ID No. 2920, Seq. ID No. 2930, Seq. ID No. 3006, Seq. ID No. 3020, Seq. ID No. 3126, Seq. ID No. 3138, Seq. ID No. 3162, Seq. ID No. 3180, Seq. ID No. 3252, Seq. ID No. 3260, Seq. ID No. 3286, Seq. ID No. 3310, Seq. ID No. 3318, Seq. ID No. 3338, Seq. ID No. 3346, Seq. ID No. 3360, Seq. ID No. 3476, Seq. ID No. 3516, Seq. ID No. 3522, Seq. ID No. 3642, Seq. ID No. 3696, Seq. ID No. 3794, Seq. ID No. 3902, Seq. ID No. 3928, Seq. ID No. 3988, Seq. ID No. 4002, Seq. ID No. 4058, Seq. ID No. 4082, Seq. ID No. 4112, Seq. ID No. 4126, Seq. ID No. 4194, Seq. ID No. 4196, Seq. ID No. 4238, Seq. ID No. 4248, Seq. ID No. 4384, Seq. ID No. 4394, Seq. ID No. 4398, Seq. ID No. 4402, Seq. ID No. 4436, Seq. ID No. 4450, Seq. ID No. 4472, Seq. ID No. 4492, Seq. ID No. 4512, Seq. ID No. 4520, Seq. ID No. 4532, Seq. ID No. 4550, Seq. ID No. 4578, Seq. ID No. 4582, Seq. ID No. 4586, Seq. ID No. 4610, Seq. ID No. 4612, Seq. ID No. 4614, Seq. ID No. 4676, Seq. ID No. 4686, Seq. ID No. 4720, Seq. ID No. 4730, Seq. ID No. 4744, Seq. ID No. 4756, Seq. ID No. 4782, Seq. ID No. 4788, Seq. ID No. 4838, Seq. ID No. 4842, Seq. ID No. 4850, Seq. ID No. 4856, Seq. ID No. 4890, Seq. ID No. 4902, Seq. ID No. 4916, Seq. ID No. 4918, Seq. ID No. 4932, Seq. ID No. 4936, Seq. ID No. 4978, Seq. ID No. 5026, Seq. ID No. 5030, Seq. ID No. 5110, Seq. ID No. 5116, Seq. ID No. 5118, Seq. ID No. 5156, Seq. ID No. 5186, Seq. ID No. 5202, Seq. ID No. 5204, Seq. ID No. 5220, Seq. ID No. 5262, Seq. ID No. 5290, Seq. ID No. 5296, Seq. ID No. 5378, Seq. ID No. 5390, Seq. ID No. 5400, Seq. ID No. 5412, Seq. ID No. 5538, Seq. ID No. 5622, Seq. ID No. 5628, Seq. ID No. 5658, Seq. ID No. 5676, Seq. ID No. 5718, Seq. ID No. 5778, Seq. ID No. 5860, Seq. ID No. 5902, Seq. ID No. 5914, Seq. ID No. 5920, Seq. ID No. 5926, Seq. ID No. 5934, Seq. ID No. 6056, Seq. ID No. 6130, Seq. ID No. 6134, Seq. ID No. 6188, Seq. ID No. 6194, Seq. ID No. 6220, Seq. ID No. 6272, Seq. ID No. 6278, Seq. ID No. 6370, Seq. ID No. 6376, Seq. ID No. 6380, Seq. ID No. 6390, Seq. ID No. 6592, and Seq. ID No.
 6606. 44. The Alloiococcus otitidis polypeptide of claim 36, wherein the polypeptide is identified as an Alloiococcus otitidis lipoprotein, and is selected from one Seq. ID No. 46, Seq. ID No. 48, Seq. ID No. 172, Seq. ID No. 226, Seq. ID No. 420, Seq. ID No. 514, Seq. ID No. 576, Seq. ID No. 592, Seq. ID No. 594, Seq. ID No. 658, Seq. ID No. 660, Seq. ID No. 670, Seq. ID No. 676, Seq. ID No. 746, Seq. ID No. 748, Seq. ID No. 936, Seq. ID No. 1046, Seq. ID No. 1076, Seq. ID No. 1138, Seq. ID No. 1174, Seq. ID No. 1192, Seq. ID No. 1194, Seq. ID No. 1196, Seq. ID No. 1564, Seq. ID No. 1662, Seq. ID No. 1664, Seq. ID No. 1666, Seq. ID No. 1792, Seq. ID No. 1798, Seq. ID No. 1918, Seq. ID No. 1970, Seq. ID No. 2116, Seq. ID No. 2160, Seq. ID No. 2430, Seq. ID No. 2528, Seq. ID No. 2700, Seq. ID No. 2816, Seq. ID No. 2876, Seq. ID No. 2976, Seq. ID No. 2978, Seq. ID No. 2992, Seq. ID No. 3044, Seq. ID No. 3324, Seq. ID No. 3338, Seq. ID No. 4134, Seq. ID No. 4138, Seq. ID No. 4482, Seq. ID No. 4706, Seq. ID No. 4828, Seq. ID No. 4870, Seq. ID No. 5116, Seq. ID No. 5378, Seq. ID No. 5380, Seq. ID No. 5492, Seq. ID No. 5510, Seq. ID No. 5514, Seq. ID No. 5526, Seq. ID No. 5530, Seq. ID No. 5532, Seq. ID No. 5890, Seq. ID No. 5910, Seq. ID No. 6026, Seq. ID No. 6028, Seq. ID No. 6088, Seq. ID No. 6090, Seq. ID No. 6326, Seq. ID No. 6328, Seq. ID No. 6416, Seq. ID No. 6638, Seq. ID No. 6640, and Seq. ID No.
 6646. 45. The Alloiococcus otitidis polypeptide of claim 36, wherein the polypeptide is identified as having a LPXTG motif and is covalently attached to the peptidoglycan layer, and is selected from one of Seq. ID No. 504, Seq. ID No. 506, Seq. ID No. 1316, Seq. ID No. 1318, Seq. ID No. 1364, Seq. ID No. 1366, Seq. ID No. 1368, Seq. ID No. 1370, Seq. ID No. 1560, Seq. ID No. 1562, Seq. ID No. 1582, Seq. ID No. 1740, Seq. ID No. 1742, Seq. ID No. 2812, Seq. ID No. 2814, Seq. ID No. 3620, Seq. ID No. 5588, Seq. ID No. 5590, Seq. ID No. 5592, Seq. ID No. 5782, Seq. ID No. 5784, and Seq. ID No.
 6104. 46. The Alloiococcus otitidis polypeptide of claim 36, wherein the polypeptide is identified as an Alloiococcus otitidis polypeptide, which is non-covalently associated with the peptidoglycan layer, and is selected from one of Seq. ID No. 3590, Seq. ID No. 3988, Seq. ID No. 5220, and Seq. ID No.
 5338. 47. The Alloiococcus otitidis polypeptide of claim 36, wherein the polypeptide is identified as an Alloiococcus otitidis polypeptide having an RGDX motif wherein X is not a proline residue and is selected from one of Seq. ID No. 38, Seq. ID No. 100, Seq. ID No. 108, Seq. ID No. 110, Seq. ID No. 112, Seq. ID No. 352, Seq. ID No. 354, Seq. ID No. 466, Seq. ID No. 468, Seq. ID No. 470, Seq. ID No. 472, Seq. ID No. 684, Seq. ID No. 822, Seq. ID No. 824, Seq. ID No. 1022, Seq. ID No. 1024, Seq. ID No. 1158, Seq. ID No. 1160, Seq. ID No. 1234, Seq. ID No. 1334, Seq. ID No. 1336, Seq. ID No. 1450, Seq. ID No. 1560, Seq. ID No. 1562, Seq. ID No. 1564, Seq. ID No. 1626, Seq. ID No. 1778, Seq. ID No. 1828, Seq. ID No. 1830, Seq. ID No. 1872, Seq. ID No. 1926, Seq. ID No. 2136, Seq. ID No. 2146, Seq. ID No. 2174, Seq. ID No. 2176, Seq. ID No. 2178, Seq. ID No. 2180, Seq. ID No. 2260, Seq. ID No. 2318, Seq. ID No. 2320, Seq. ID No. 2322, Seq. ID No. 2324, Seq. ID No. 2326, Seq. ID No. 2328, Seq. ID No. 2330, Seq. ID No. 2402, Seq. ID No. 2672, Seq. ID No. 2864, Seq. ID No. 2870, Seq. ID No. 2920, Seq. ID No. 2922, Seq. ID No. 2994, Seq. ID No. 3088, Seq. ID No. 3138, Seq. ID No. 3280, Seq. ID No. 3282, Seq. ID No. 3284, Seq. ID No. 3334, Seq. ID No. 3336, Seq. ID No. 3498, Seq. ID No. 3500, Seq. ID No. 3502, Seq. ID No. 3534, Seq. ID No. 3672, Seq. ID No. 3674, Seq. ID No. 3676, Seq. ID No. 3838, Seq. ID No. 3840, Seq. ID No. 3842, Seq. ID No. 3844, Seq. ID No. 3930, Seq. ID No. 3962, Seq. ID No. 4038, Seq. ID No. 4194, Seq. ID No. 4240, Seq. ID No. 4328, Seq. ID No. 4330, Seq. ID No. 4334, Seq. ID No. 4394, Seq. ID No. 4464, Seq. ID No. 4466, Seq. ID No. 4468, Seq. ID No. 4598, Seq. ID No. 4630, Seq. ID No. 4632, Seq. ID No. 4676, Seq. ID No. 4678, Seq. ID No. 4680, Seq. ID No. 4690, Seq. ID No. 4692, Seq. ID No. 4694, Seq. ID No. 4782, Seq. ID No. 4800, Seq. ID No. 4802, Seq. ID No. 4804, Seq. ID No. 4862, Seq. ID No. 5010, Seq. ID No. 5144, Seq; ID No. 5146, Seq. ID No. 5180, Seq. ID No. 5182, Seq. ID No. 5184, Seq. ID No. 5250, Seq. ID No. 5252, Seq. ID No. 5254, Seq. ID No. 5260, Seq. ID No. 5262, Seq. ID No. 5294, Seq. ID No. 5296, Seq. ID No. 5298, Seq. ID No. 5300, Seq. ID No. 5308, Seq. ID No. 5310, Seq. ID No. 5412, Seq. ID No. 5536, Seq. ID No. 5538, Seq. ID No. 5746, Seq. ID No. 5822, Seq. ID No. 5824, Seq. ID No. 5826, Seq. ID No. 6030, Seq. ID No. 6172, Seq. ID No. 6308, Seq. ID No. 6310, and Seq. ID No.
 6312. 48. The Alloiococcus otitidis polypeptide of claim 36, wherein the polypeptide is predicted by BlastP as being involved in capsule biosynthesis and transport, and is selected from one of Seq. ID No. 50, Seq. ID No. 52, Seq. ID No. 54, Seq. ID No. 60, Seq. ID No. 196, Seq. ID No. 690, Seq. ID No. 704, Seq. ID No. 926, Seq. ID No. 1598, Seq. ID No. 1602, Seq. ID No. 1608, Seq. ID No. 1612, Seq. ID No. 1614, Seq. ID No. 1714, Seq. ID No. 2030, Seq. ID No. 2264, Seq. ID No. 2270, Seq. ID No. 2374, Seq. ID No. 2438, Seq. ID No. 2652, Seq. ID No. 2768, Seq. ID No. 2908, Seq. ID No. 3398, Seq. ID No. 3400, Seq. ID No. 3480, Seq. ID No. 3488, Seq. ID No. 3492, Seq. ID No. 3494, Seq. ID No. 3496, Seq. ID No. 3498, Seq. ID No. 3520, Seq. ID No. 3522, Seq. ID No. 3530, Seq. ID No. 3536, Seq. ID No. 3562, Seq. ID No. 3884, Seq. ID No. 3892, Seq. ID No. 3982, and Seq. ID No.
 4088. 49. The Alloiococcus otitidis polypeptide of claim 36 wherein the polynucleotide encoding the polypeptide is predicted by BlastP as being localized in the capsule loci region of Alloiococcus otitidis, and is selected from one of Seq. ID No. 46, Seq. ID No. 48, Seq. ID No. 52, Seq. ID No. 54, Seq. ID No. 56, Seq. ID No. 58, Seq. ID No. 60, Seq. ID No. 684, Seq. ID No. 686, Seq. ID No. 688, Seq. ID No. 690, Seq. ID No. 692, Seq. ID No. 694, Seq. ID No. 696, Seq. ID No. 698, Seq. ID No. 700, Seq. ID No. 702, Seq. ID No. 704, Seq. ID No. 706, Seq. ID No. 708, Seq. ID No. 710, Seq. ID No. 712, Seq. ID No. 714, Seq. ID No. 716, Seq. ID No. 718, Seq. ID No. 720, Seq. ID No. 722, Seq. ID No. 724, Seq. ID No. 726, Seq. ID No. 728, Seq. ID No. 730, Seq. ID No. 732, Seq. ID No. 734, Seq. ID No. 736, Seq. ID No. 738, Seq. ID No. 740, Seq. ID No. 742, Seq. ID No. 744, Seq. ID No. 746, Seq. ID No. 748, Seq. ID No. 750, Seq. ID No. 752, Seq. ID No. 754, Seq. ID No. 3390, Seq. ID No. 3392, Seq. ID No. 3394, Seq. ID No. 3396, Seq. ID No. 3398, Seq. ID No. 3400, Seq. ID No. 3402, Seq. ID No. 3404, Seq. ID No. 3406, Seq. ID No. 3408, Seq. ID No. 3410, Seq. ID No. 3412, Seq. ID No. 3414, Seq. ID No. 3416, Seq. ID No. 3418, Seq. ID No. 3420, Seq. ID No. 3422, Seq. ID No. 3424, Seq. ID No. 3426, Seq. ID No. 3428, Seq. ID No. 3430, Seq. ID No. 3432, Seq. ID No. 3434, Seq. ID No. 3436, Seq. ID No. 3438, Seq. ID No. 3440, Seq. ID No. 3442, Seq. ID No. 3444, Seq. ID No. 3446, Seq. ID No. 3448, Seq. ID No. 3450, Seq. ID No. 3452, Seq. ID No. 3454, Seq. ID No. 3456, Seq. ID No. 3458, Seq. ID No. 3460, Seq. ID No. 3462, Seq. ID No. 3464, Seq. ID No. 3466, Seq. ID No. 3468, Seq. ID No. 3470, Seq. ID No. 3472, Seq. ID No. 3474, Seq. ID No. 3476, Seq. ID No. 3478, Seq. ID No. 3480, Seq. ID No. 3482, Seq. ID No. 3484, Seq. ID No. 3486, Seq. ID No. 3488, Seq. ID No. 3490, Seq. ID No. 3492, Seq. ID No. 3494, Seq. ID No. 3496, Seq. ID No. 3498, Seq. ID No. 3500, Seq. ID No. 3502, Seq. ID No. 3504, Seq. ID No. 3506, Seq. ID No. 3508, Seq. ID No. 3510, Seq. ID No. 3512, Seq. ID No. 3514, Seq. ID No. 3516, Seq. ID No. 3518, Seq. ID No. 3520, Seq. ID No. 3522, Seq. ID No. 3524, Seq. ID No. 3526, Seq. ID No. 3528, Seq. ID No. 3530, Seq. ID No. 3532, Seq. ID No. 3534, Seq. ID No. 3536, Seq. ID No. 3538, Seq. ID No. 3540, Seq. ID No. 3542, Seq. ID No. 3544, Seq. ID No. 3546, Seq. ID No. 3548, Seq. ID No. 3550, Seq. ID No. 3552, Seq. ID No. 3554, Seq. ID No. 3556, Seq. ID No. 3558, Seq. ID No. 3560, and Seq. ID No.
 3562. 50. The Alloiococcus otitidis polypeptide of claim 36, wherein the polypeptide is predicted by BlastP to be associated with sporulation, and is selected from one of Seq. ID No. 1138, Seq. ID No. 1456, Seq. ID No. 2138, Seq. ID No. 2142, Seq. ID No. 2166, Seq. ID No. 2180, Seq. ID No. 2302, Seq. ID No. 2754, Seq. ID No. 4212, Seq. ID No. 4252, Seq. ID No. 4328, Seq. ID No. 4570, Seq. ID No. 4720, and Seq. ID No.
 4730. 51. The Alloiococcus otitidis polypeptide of claim 36 wherein the polypeptide encoded by the polynucleotide is predicted by BlastP to be a unique polypeptide, and is selected from one of Seq. ID No. 8, Seq. ID No. 20, Seq. ID No. 22, Seq. ID No. 24, Seq. ID No. 32, Seq. ID No. 40, Seq. ID No. 66, Seq. ID No. 68, Seq. ID No. 70, Seq. ID No. 92, Seq. ID No. 100, Seq. ID No. 106, Seq. ID No. 114, Seq. ID No. 116, Seq. ID No. 124, Seq. ID No. 126, Seq. ID No. 128, Seq. ID No. 132, Seq. ID No. 134, Seq. ID No. 140, Seq. ID No. 152, Seq. ID No. 160, Seq. ID No. 162, Seq. ID No. 164, Seq. ID No. 166, Seq. ID No. 170, Seq. ID No. 186, Seq. ID No. 190, Seq. ID No. 194, Seq. ID No. 230, Seq. ID No. 232, Seq. ID No. 256, Seq. ID No. 258, Seq. ID No. 260, Seq. ID No. 276, Seq. ID No. 338, Seq. ID No. 340, Seq. ID No. 348, Seq. ID No. 350, Seq. ID No. 358, Seq. ID No. 360, Seq. ID No. 370, Seq. ID No. 372, Seq. ID No. 378, Seq. ID No. 386, Seq. ID No. 388, Seq. ID No. 394, Seq. ID No. 400, Seq. ID No. 402, Seq. ID No. 404, Seq. ID No. 408, Seq. ID No. 420, Seq. ID No. 432, Seq. ID No. 478, Seq. ID No. 496, Seq. ID No. 508, Seq. ID No. 520, Seq. ID No. 542, Seq. ID No. 546, Seq. ID No. 548, Seq. ID No. 550, Seq. ID No. 558, Seq. ID No. 590, Seq. ID No. 618, Seq. ID No. 620, Seq. ID No. 634, Seq. ID No. 640, Seq. ID No. 642, Seq. ID No. 644, Seq. ID No. 646, Seq. ID No. 648, Seq. ID No. 652, Seq. ID No. 654, Seq. ID No. 656, Seq. ID No. 668, Seq. ID No. 692, Seq. ID No. 694, Seq. ID No. 696, Seq. ID No. 698, Seq. ID No. 716, Seq. ID No. 718, Seq. ID No. 720, Seq. ID No. 732, Seq. ID No. 734, Seq. ID No. 742, Seq. ID No. 744, Seq. ID No. 746, Seq. ID No. 748, Seq. ID No. 750, Seq. ID No. 752, Seq. ID No. 756, Seq. ID No. 758, Seq. ID No. 760, Seq. ID No. 762, Seq. ID No. 764, Seq. ID No. 766, Seq. ID No. 768, Seq. ID No. 802, Seq. ID No. 804, Seq. ID No. 806, Seq. ID No. 808, Seq. ID No. 810, Seq. ID No. 812, Seq. ID No. 814, Seq. ID No. 834, Seq. ID No. 842, Seq. ID No. 850, Seq. ID No. 852, Seq. ID No. 854, Seq. ID No. 856, Seq. ID No. 888, Seq. ID No. 890, Seq. ID No. 892, Seq. ID No. 904, Seq. ID No. 906, Seq. ID No. 910, Seq. ID No. 938, Seq. ID No. 942, Seq. ID No. 944, Seq. ID No. 952, Seq. ID No. 958, Seq. ID No. 974, Seq. ID No. 976, Seq. ID No. 988, Seq. ID No. 1006, Seq. ID No. 1008, Seq. ID No. 1010, Seq: ID No. 1012, Seq. ID No. 1020, Seq. ID No. 1026, Seq. ID No. 1028, Seq. ID No. 1046, Seq. ID No. 1048, Seq. ID No. 1072, Seq. ID No. 1074, Seq. ID No. 1078, Seq. ID No. 1106, Seq. ID No. 1108, Seq. ID No. 1112, Seq. ID No. 1132, Seq. ID No. 1136, Seq. ID No. 1140, Seq. ID No. 1152, Seq. ID No. 1154, Seq. ID No. 1166, Seq. ID No. 1168, Seq. ID No. 1170, Seq. ID No. 1172, Seq. ID No. 1174, Seq. ID No. 1182, Seq. ID No. 1184, Seq. ID No. 1186, Seq. ID No. 1188, Seq. ID No. 1190, Seq. ID No. 1192, Seq. ID No. 1194, Seq. ID No. 1196, Seq. ID No. 1198, Seq. ID No. 1200, Seq. ID No. 1202, Seq. ID No. 1204, Seq. ID No. 1208, Seq. ID No. 1214, Seq. ID No. 1228, Seq. ID No. 1230, Seq. ID No. 1240, Seq. ID No. 1244, Seq. ID No. 1246, Seq. ID No. 1248, Seq. ID No. 1250, Seq. ID No. 1260, Seq. ID No. 1266, Seq. ID No. 1268, Seq. ID No. 1270, Seq. ID No. 1272, Seq. ID No. 1274, Seq. ID No. 1276, Seq. ID No. 1278, Seq. ID No. 1280, Seq. ID No. 1282, Seq. ID No. 1284, Seq. ID No. 1286, Seq. ID No. 1288, Seq. ID No. 1290, Seq. ID No. 1292, Seq. ID No. 1294, Seq. ID No. 1296, Seq. ID No. 1298, Seq. ID No. 1300, Seq. ID No. 1302, Seq. ID No. 1304, Seq. ID No. 1306, Seq. ID No. 1308, Seq. ID No. 1310, Seq. ID No. 1312, Seq. ID No. 1314, Seq. ID No. 1320, Seq. ID No. 1322, Seq. ID No. 1324, Seq. ID No. 1326, Seq. ID No. 1328, Seq. ID No. 1338, Seq. ID No. 1342, Seq. ID No. 1344, Seq. ID No. 1348, Seq. ID No. 1350, Seq. ID No. 1352, Seq. ID No. 1354, Seq. ID No. 1356, Seq. ID No. 1372, Seq. ID No. 1380, Seq. ID No. 1382, Seq. ID No. 1390, Seq. ID No. 1398, Seq. ID No. 1400, Seq. ID No. 1402, Seq. ID No. 1418, Seq. ID No. 1420, Seq. ID No. 1422, Seq. ID No. 1424, Seq. ID No. 1440, Seq. ID No. 1446, Seq. ID No. 1448, Seq. ID No. 1458, Seq. ID No. 1466, Seq. ID No. 1480, Seq. ID No. 1512, Seq. ID No. 1552, Seq. ID No. 1554, Seq. ID No. 1556, Seq. ID No. 1558, Seq. ID No. 1580, Seq. ID No. 1610, Seq. ID No. 1622, Seq. ID No. 1624, Seq. ID No. 1626, Seq. ID No. 1628, Seq. ID No. 1630, Seq. ID No. 1632, Seq. ID No. 1634, Seq. ID No. 1640, Seq. ID No. 1644, Seq. ID No. 1656, Seq. ID No. 1668, Seq. ID No. 1672, Seq. ID No. 1694, Seq. ID No. 1696, Seq. ID No. 1702, Seq. ID No. 1704, Seq. ID No. 1706, Seq. ID No. 1722, Seq. ID No. 1724, Seq. ID No. 1732, Seq. ID No. 1738, Seq. ID No. 1744, Seq. ID No. 1760, Seq. ID No. 1764, Seq. ID No. 1774, Seq. ID No. 1776, Seq. ID No. 1778, Seq. ID No. 1780, Seq. ID No. 1782, Seq. ID No. 1800, Seq. ID No. 1802, Seq. ID No. 1804, Seq. ID No. 1808, Seq. ID No. 1824, Seq. ID No. 1832, Seq. ID No. 1852, Seq. ID No. 1858, Seq. ID No. 1876, Seq. ID No. 1900, Seq. ID No. 1916, Seq. ID No. 1928, Seq. ID No. 1930, Seq. ID No. 1974, Seq. ID No. 1978, Seq. ID No. 1982, Seq. ID No. 2006, Seq. ID No. 2008, Seq. ID No. 2010, Seq. ID No. 2012, Seq. ID No. 2018, Seq. ID No. 2020, Seq. ID No. 2024, Seq. ID No. 2026, Seq. ID No. 2028, Seq. ID No. 2040, Seq. ID No. 2042, Seq. ID No. 2044, Seq. ID No. 2046, Seq. ID No. 2050, Seq. ID No. 2082, Seq. ID No. 2084, Seq. ID No. 2086, Seq. ID No. 2106, Seq. ID No. 2108, Seq. ID No. 2110, Seq. ID No. 2112, Seq. ID No. 2130, Seq. ID No. 2132, Seq. ID No. 2134, Seq. ID No. 2146, Seq. ID No. 2156, Seq. ID No. 2158, Seq. ID No. 2160, Seq. ID No. 2162, Seq. ID No. 2172, Seq. ID No. 2188, Seq. ID No. 2190, Seq. ID No. 2202, Seq. ID No. 2204, Seq. ID No. 2210, Seq. ID No. 2212, Seq. ID No. 2920, Seq. ID No. 2226, Seq. ID No. 2244, Seq. ID No. 2246, Seq. ID No. 2248, Seq. ID No. 2250, Seq. ID No. 2252, Seq. ID No. 2256, Seq. ID No. 2278, Seq. ID No. 2280, Seq. ID No. 2342, Seq. ID No. 2352, Seq. ID No. 2354, Seq. ID No. 2356, Seq. ID No. 2358, Seq. ID No. 2360, Seq. ID No. 2366, Seq. ID No. 2368, Seq. ID No. 2372, Seq. ID No. 2376, Seq. ID No. 2394, Seq. ID No. 2396, Seq. ID No. 2426, Seq. ID No. 2428, Seq. ID No. 2432, Seq. ID No. 2440, Seq. ID No. 2442, Seq. ID No. 2444, Seq. ID No. 2448, Seq. ID No. 2460, Seq. ID No. 2480, Seq. ID No. 2494, Seq. ID No. 2502, Seq. ID No. 2504, Seq. ID No. 2522, Seq. ID No. 2524, Seq. ID No. 2528, Seq. ID No. 2592, Seq. ID No. 2602, Seq. ID No. 2604, Seq. ID No. 2612, Seq. ID No. 2628, Seq. ID No. 2630, Seq. ID No. 2654, Seq. ID No. 2662, Seq. ID No. 2692, Seq. ID No. 2696, Seq. ID No. 2698, Seq. ID No. 2718, Seq. ID No. 2730, Seq. ID No. 2732, Seq. ID No. 2734, Seq. ID No. 2736, Seq. ID No. 2740, Seq. ID No. 2742, Seq. ID No. 2744, Seq. ID No. 2778, Seq. ID No. 2780, Seq. ID No. 2782, Seq. ID No. 2784, Seq. ID No. 2802, Seq. ID No. 2806, Seq. ID No. 2808, Seq. ID No. 2810, Seq. ID No. 2812, Seq. ID No. 2814, Seq. ID No. 2816, Seq. ID No. 2818, Seq. ID No. 2820, Seq. ID No. 2830, Seq. ID No. 2832, Seq. ID No. 2834, Seq. ID No. 2836, Seq. ID No. 2838, Seq. ID No. 2840, Seq. ID No. 2842, Seq. ID No. 2846, Seq. ID No. 2850, Seq. ID No. 2852, Seq. ID No. 2854, Seq. ID No. 2856, Seq. ID No. 2858, Seq. ID No. 2860, Seq. ID No. 2862, Seq. ID No. 2866, Seq. ID No. 2874, Seq. ID No. 2876, Seq. ID No. 2878, Seq. ID No. 2884, Seq. ID No. 2886, Seq. ID No. 2888, Seq. ID No. 2890, Seq. ID No. 2894, Seq. ID No. 2896, Seq. ID No. 2904, Seq. ID No. 2910, Seq. ID No. 2936, Seq. ID No. 2938, Seq. ID No. 2940, Seq. ID No. 2942, Seq. ID No. 2944, Seq. ID No. 2946, Seq. ID No. 2948, Seq. ID No. 2950, Seq. ID No. 2952, Seq. ID No. 2954, Seq. ID No. 2966, Seq. ID No. 2968, Seq. ID No. 2974, Seq. ID No. 2976, Seq. ID No. 2978, Seq. ID No. 2982, Seq. ID No. 2984, Seq. ID No. 2986, Seq. ID No. 2988, Seq. ID No. 2990, Seq. ID No. 2992, Seq. ID No. 3002, Seq. ID No. 3008, Seq. ID No. 3010, Seq. ID No. 3012, Seq. ID No. 3022, Seq. ID No. 3024, Seq. ID No. 3042, Seq. ID No. 3046, Seq. ID No. 3072, Seq. ID No. 3088, Seq. ID No. 3106, Seq. ID No. 3108, Seq. ID No. 3120, Seq. ID No. 3122, Seq. ID No. 3124, Seq. ID No. 3152, Seq. ID No. 3154, Seq. ID No. 3168, Seq. ID No. 3174, Seq. ID No. 3176, Seq. ID No. 3178, Seq. ID No. 3182, Seq. ID No. 3194, Seq. ID No. 3214, Seq. ID No. 3216, Seq. ID No. 3218, Seq. ID No. 3220, Seq. ID No. 3222, Seq. ID No. 3224, Seq. ID No. 3232, Seq. ID No. 3234, Seq. ID No. 3236, Seq. ID No. 3238, Seq. ID No. 3240, Seq. ID No. 3242, Seq. ID No. 3244, Seq. ID No. 3246, Seq. ID No. 3248, Seq. ID No. 3250, Seq. ID No. 3262, Seq. ID No. 3264, Seq. ID No. 3266, Seq. ID No. 3268, Seq. ID No. 3270, Seq. ID No. 3272, Seq. ID No. 3274, Seq. ID No. 3276, Seq. ID No. 3278, Seq. ID No. 3326, Seq. ID No. 3332, Seq. ID No. 3340, Seq. ID No. 3342, Seq. ID No. 3350, Seq. ID No. 3362, Seq. ID No. 3364, Seq. ID No. 3370, Seq. ID No. 3372, Seq. ID No. 3390, Seq. ID No. 3404, Seq. ID No. 3418, Seq. ID No. 3420, Seq. ID No. 3422, Seq. ID No. 3434, Seq. ID No. 3438, Seq. ID No. 3442, Seq. ID No. 3444, Seq. ID No. 3446, Seq. ID No. 3448, Seq. ID No. 3474, Seq. ID No. 3482, Seq. ID No. 3484, Seq. ID No. 3490, Seq. ID No. 3504, Seq. ID No. 3506, Seq. ID No. 3510, Seq. ID No. 3512, Seq. ID No. 3524, Seq. ID No. 3526, Seq. ID No. 3532, Seq. ID No. 3534, Seq. ID No. 3540, Seq. ID No. 3542, Seq. ID No. 3544, Seq. ID No. 3546, Seq. ID No. 3548, Seq. ID No. 3556, Seq. ID No. 3558, Seq. ID No. 3564, Seq. ID No. 3566, Seq. ID No. 3572, Seq. ID No. 3574, Seq. ID No. 3582, Seq. ID No. 3588, Seq. ID No. 3592, Seq. ID No. 3594, Seq. ID No. 3596, Seq. ID No. 3612, Seq. ID No. 3614, Seq. ID No. 3618, Seq. ID No. 3620, Seq. ID No. 3622, Seq. ID No. 3624, Seq. ID No. 3626, Seq. ID No. 3632, Seq. ID No. 3638, Seq. ID No. 3640, Seq. ID No. 3656, Seq. ID No. 3658, Seq. ID No. 3660, Seq. ID No. 3662, Seq. ID No. 3678, Seq. ID No. 3680, Seq. ID No. 3684, Seq. ID No. 3686, Seq. ID No. 3702, Seq. ID No. 3704, Seq. ID No. 3718, Seq. ID No. 3720, Seq. ID No. 3722, Seq. ID No. 3724, Seq. ID No. 3730, Seq. ID No. 3732, Seq. ID No. 3734, Seq. ID No. 3736, Seq. ID No. 3738, Seq. ID No. 3740, Seq. ID No. 3742, Seq. ID No. 3750, Seq. ID No. 3752, Seq. ID No. 3754, Seq. ID No. 3756, Seq. ID No. 3762, Seq. ID No. 3782, Seq. ID No. 3784, Seq. ID No. 3786, Seq. ID No. 3788, Seq. ID No. 3790, Seq. ID No. 3792, Seq. ID No. 3800, Seq. ID No. 3808, Seq. ID No. 3810, Seq. ID No. 3812, Seq. ID No. 3814, Seq. ID No. 3816, Seq. ID No. 3818, Seq. ID No. 3828, Seq. ID No. 3830, Seq. ID No. 3832, Seq. ID No. 3834, Seq. ID No. 3836, Seq. ID No. 3850, Seq. ID No. 3880, Seq. ID No. 3882, Seq. ID No. 3896, Seq. ID No. 3904, Seq. ID No. 3910, Seq. ID No. 3916, Seq. ID No. 3940, Seq. ID No. 3960, Seq. ID No. 3962, Seq. ID No. 3964, Seq. ID No. 3966, Seq. ID No. 3974, Seq. ID No. 3978, Seq. ID No. 3980, Seq. ID No. 3994, Seq. ID No. 3996, Seq. ID No. 3998, Seq. ID No. 4006, Seq: ID No. 4008, Seq. ID No. 4010, Seq. ID No. 4042, Seq. ID No. 4044, Seq. ID No. 4046, Seq. ID No. 4070, Seq. ID No. 4078, Seq. ID No. 4098, Seq. ID No. 4114, Seq. ID No. 4124, Seq. ID No. 4132, Seq. ID No. 4134, Seq. ID No. 4136, Seq. ID No. 4140, Seq. ID No. 4152, Seq. ID No. 4154, Seq. ID No. 4156, Seq. ID No. 4182, Seq. ID No. 4222, Seq. ID No. 4242, Seq. ID No. 4254, Seq. ID No. 4258, Seq. ID No. 4260, Seq. ID No. 4262, Seq. ID No. 4264, Seq. ID No. 4266, Seq. ID No. 4270, Seq. ID No. 4276, Seq. ID No. 4278, Seq. ID No. 4280, Seq. ID No. 4282, Seq. ID No. 4286, Seq. ID No. 4288, Seq. ID No. 4298, Seq. ID No. 4306, Seq. ID No. 4308, Seq. ID No. 4364, Seq. ID No. 4366, Seq. ID No. 4372, Seq. ID No. 4374, Seq. ID No. 4396, Seq. ID No. 4400; Seq. ID No. 4404, Seq. ID No. 4426, Seq. ID No. 4438, Seq. ID No. 4440, Seq. ID No. 4442, Seq. ID No. 4454, Seq. ID No. 4456, Seq. ID No. 4514, Seq. ID No. 4516, Seq. ID No. 4552, Seq. ID No. 4562, Seq. ID No. 4574, Seq. ID No. 4576, Seq. ID No. 4588, Seq. ID No. 4590, Seq. ID No. 4592, Seq. ID No. 4594, Seq. ID No. 4596, Seq. ID No. 4618, Seq. ID No. 4620, Seq. ID No. 4622, Seq. ID No. 4626, Seq. ID No. 4628, Seq. ID No. 4634, Seq. ID No. 4636, Seq. ID No. 4638, Seq. ID No. 4640, Seq. ID No. 4660, Seq. ID No. 4682, Seq. ID No. 4688, Seq. ID No. 4696, Seq. ID No. 4700, Seq. ID No. 4702, Seq. ID No. 4722, Seq. ID No. 4736, Seq. ID No. 4738, Seq. ID No. 4742, Seq. ID No. 4784, Seq. ID No. 4790, Seq. ID No. 4806, Seq. ID No. 4812, Seq. ID No. 4818, Seq. ID No. 4820, Seq. ID No. 4822, Seq. ID No. 4824, Seq. ID No. 4836, Seq. ID No. 4854, Seq. ID No. 4886, Seq. ID No. 4914, Seq. ID No. 4924, Seq. ID No. 4950, Seq. ID No. 4952, Seq. ID No. 4976, Seq. ID No. 4982, Seq. ID No. 4984, Seq. ID No. 4988, Seq. ID No. 4994, Seq. ID No. 5000, Seq. ID No. 5002, Seq. ID No. 5012, Seq. ID No. 5014, Seq. ID No. 5024, Seq. ID No. 5032, Seq. ID No. 5034, Seq. ID No. 5036, Seq. ID No. 5038, Seq. ID No. 5042, Seq. ID No. 5044, Seq. ID No. 5054, Seq. ID No. 5062, Seq. ID No. 5064, Seq. ID No. 5086, Seq. ID No. 5094, Seq. ID No. 5152, Seq. ID No. 5154, Seq. ID No. 5160, Seq. ID No. 5162, Seq. ID No. 5168, Seq. ID No. 5174, Seq. ID No. 5176, Seq. ID No. 5178, Seq. ID No. 5190, Seq. ID No. 5192, Seq. ID No. 5194, Seq. ID No. 5198, Seq. ID No. 5200, Seq. ID No. 5222, Seq. ID No. 5224, Seq. ID No. 5226, Seq. ID No. 5228, Seq. ID No. 5238, Seq. ID No. 5268, Seq. ID No. 5270, Seq. ID No. 5272, Seq. ID No. 5282, Seq. ID No. 5302, Seq. ID No. 5304, Seq. ID No. 5316, Seq. ID No. 5322, Seq. ID No. 5328, Seq. ID No. 5348, Seq. ID No. 5386, Seq. ID No. 5446, Seq. ID No. 5448, Seq. ID No. 5460, Seq. ID No. 5466, Seq. ID No. 5468, Seq. ID No. 5480, Seq. ID No. 5482, Seq. ID No. 5486, Seq. ID No. 5488, Seq. ID No. 5516, Seq. ID No. 5518, Seq. ID No. 5534, Seq. ID No. 5544, Seq. ID No. 5546, Seq. ID No. 5550, Seq. ID No. 5570, Seq. ID No. 5578, Seq. ID No. 5594, Seq. ID No. 5596, Seq. ID No. 5610, Seq. ID No. 5624, Seq. ID No. 5626, Seq. ID No. 5640, Seq. ID No. 5642, Seq. ID No. 5644, Seq. ID No. 5650, Seq. ID No. 5660, Seq. ID No. 5662, Seq. ID No. 5664, Seq. ID No. 5668, Seq. ID No. 5672, Seq. ID No. 5688, Seq. ID No. 5690, Seq. ID No. 5704, Seq. ID No. 5706, Seq. ID No. 5710, Seq. ID No. 5712, Seq. ID No. 5738, Seq. ID No. 5740, Seq. ID No. 5746, Seq. ID No. 5752, Seq. ID No. 5764, Seq. ID No. 5798, Seq. ID No. 5812, Seq. ID No. 5814, Seq. ID No. 5816, Seq. ID No. 5828, Seq. ID No. 5830, Seq. ID No. 5844, Seq. ID No. 5846, Seq. ID No. 5874, Seq. ID No. 5880, Seq. ID No. 5884, Seq. ID No. 5886, Seq. ID No. 5888, Seq. ID No. 5890, Seq. ID No. 5892, Seq. ID No. 5932, Seq. ID No. 5956, Seq. ID No. 5964, Seq. ID No. 5966, Seq. ID No. 5976, Seq. ID No. 5984, Seq. ID No. 5986, Seq. ID No. 5988, Seq. ID No. 5990, Seq. ID No. 6006, Seq. ID No. 6014, Seq. ID No. 6032, Seq. ID No. 6036, Seq. ID No. 6046, Seq. ID No. 6060, Seq. ID No. 6062, Seq. ID No. 6064, Seq. ID No. 6074, Seq. ID No. 6082, Seq. ID No. 6092, Seq. ID No. 6094, Seq. ID No. 6128, Seq. ID No. 6160, Seq. ID No. 6198, Seq. ID No. 6200, Seq. ID No. 6204, Seq. ID No. 6218, Seq. ID No. 6222, Seq. ID No. 6224, Seq. ID No. 6238, Seq. ID No. 6240, Seq. ID No. 6242, Seq. ID No. 6246, Seq. ID No. 6248, Seq. ID No. 6250, Seq. ID No. 6260, Seq. ID No. 6266, Seq. ID No. 6268, Seq. ID No. 6274, Seq. ID No. 6284, Seq. ID No. 6286, Seq. ID No. 6324, Seq. ID No. 6326, Seq. ID No. 6328, Seq. ID No. 6362, Seq. ID No. 6364, Seq. ID No. 6378, Seq. ID No. 6382, Seq. ID No. 6402, Seq. ID No. 6404, Seq. ID No. 6420, Seq. ID No. 6426, Seq. ID No. 6428, Seq. ID No. 6430, Seq. ID No. 6432, Seq. ID No. 6434, Seq. ID No. 6436, Seq. ID No. 6438, Seq. ID No. 6440, Seq. ID No. 6448, Seq. ID No. 6450, Seq. ID No. 6452, Seq. ID No. 6454, Seq. ID No. 6456, Seq. ID No. 6458, Seq. ID No. 6466, Seq. ID No. 6468, Seq. ID No. 6470, Seq. ID No. 6472, Seq. ID No. 6474, Seq. ID No. 6476, Seq. ID No. 6478, Seq. ID No. 6480, Seq. ID No. 6482, Seq. ID No. 6484, Seq. ID No. 6486, Seq. ID No. 6488, Seq. ID No. 6490, Seq. ID No. 6492, Seq. ID No. 6496, Seq. ID No. 6498, Seq. ID No. 6508, Seq. ID No. 6518, Seq. ID No. 6520, Seq. ID No. 6522, Seq. ID No. 6524, Seq. ID No. 6526, Seq. ID No. 6528, Seq. ID No. 6530, Seq. ID No. 6534, Seq. ID No. 6540, Seq. ID No. 6542, Seq. ID No. 6544, Seq. ID No. 6556, Seq. ID No. 6558, Seq. ID No. 6562, Seq. ID No. 6564, Seq. ID No. 6566, Seq. ID No. 6568, Seq. ID No. 6570, Seq. ID No. 6572, Seq. ID No. 6574, Seq. ID No. 6582, Seq. ID No. 6584, Seq. ID No. 6632, Seq. ID No. 6636, Seq. ID No. 6638, Seq. ID No. 6640, Seq. ID No. 6644, Seq. ID No. 6646, Seq. ID No. 6648, and Seq. ID No.
 6650. 52. The Alloiococcus otitidis polypeptide of claim 36, wherein the polypeptide is identified as an Alloiococcus otitidis polypeptide identified by Glimmer™ ORF finder program, and is selected from one of Seq. ID No. 2, Seq. ID No. 6, Seq. ID No. 12, Seq. ID No. 14, Seq. ID No. 16, Seq. ID No. 18, Seq. ID No. 26, Seq. ID No. 28, Seq. ID No. 30, Seq. ID No. 36, Seq. ID No. 38, Seq. ID No. 42, Seq. ID No. 44, Seq. ID No. 48, Seq. ID No. 52, Seq. ID No. 54, Seq. ID No. 60, Seq. ID No. 64, Seq. ID No. 70, Seq. ID No. 74, Seq. ID No. 76, Seq. ID No. 82, Seq. ID No. 84, Seq. ID No. 90, Seq. ID No. 94, Seq. ID No. 98, Seq. ID No. 104, Seq. ID No. 112, Seq. ID No. 122, Seq. ID No. 126, Seq. ID No. 130, Seq. ID No. 136, Seq. ID No. 138, Seq. ID No. 146, Seq. ID No. 150, Seq. ID No. 158, Seq. ID No. 168, Seq. ID No. 174, Seq. ID No. 184, Seq. ID No. 188, Seq. ID No. 190, Seq. ID No. 192, Seq. ID No. 196, Seq. ID No. 198, Seq. ID No. 204, Seq. ID No. 208, Seq. ID No. 216, Seq. ID No. 220, Seq. ID No. 224, Seq. ID No. 226, Seq. ID No. 228, Seq. ID No. 232, Seq. ID No. 234, Seq. ID No. 240, Seq. ID No. 242, Seq. ID No. 248, Seq. ID No. 254, Seq. ID No. 262, Seq. ID No. 266, Seq. ID No. 270, Seq. ID No. 274, Seq. ID No. 276, Seq. ID No. 278, Seq. ID No. 284, Seq. ID No. 292, Seq. ID No. 294, Seq. ID No. 298, Seq. ID No. 302, Seq. ID No. 308, Seq. ID No. 310, Seq. ID No. 314, Seq. ID No. 318, Seq. ID No. 322, Seq. ID No. 326, Seq. ID No. 336, Seq. ID No. 344, Seq. ID No. 346, Seq. ID No. 354, Seq. ID No. 356, Seq. ID No. 362, Seq. ID No. 364, Seq. ID No. 368, Seq. ID No. 376, Seq. ID No. 380, Seq. ID No. 384, Seq. ID No. 390, Seq. ID No. 392, Seq. ID No. 398, Seq. ID No. 406, Seq. ID No. 412, Seq. ID No. 416, Seq. ID No. 418, Seq. ID No. 424, Seq. ID No. 426, Seq. ID No. 428, Seq. ID No. 430, Seq. ID No. 436, Seq. ID No. 438, Seq. ID No. 440, Seq. ID No. 442, Seq. ID No. 446, Seq. ID No. 448, Seq. ID No. 454, Seq. ID No. 462, Seq. ID No. 464, Seq. ID No. 472, Seq. ID No. 486, Seq. ID No. 502, Seq. ID No. 506, Seq. ID No. 512, Seq. ID No. 516, Seq. ID No. 518, Seq. ID No. 522, Seq. ID No. 524, Seq. ID No. 532, Seq. ID No. 534, Seq. ID No. 540, Seq. ID No. 542, Seq. ID No. 544, Seq. ID No. 552, Seq. ID No. 556, Seq. ID No. 562, Seq. ID No. 566, Seq. ID No. 570, Seq. ID No. 576, Seq. ID No. 580, Seq. ID No. 588, Seq. ID No. 594, Seq. ID No. 598, Seq. ID No. 604, Seq. ID No. 606, Seq. ID No. 610, Seq. ID No. 612, Seq. ID No. 614, Seq. ID No. 616, Seq. ID No. 624, Seq. ID No. 628, Seq. ID No. 630, Seq. ID No. 632, Seq. ID No. 636, Seq. ID No. 638, Seq. ID No. 648, Seq. ID No. 650, Seq. ID No. 662, Seq. ID No. 670, Seq. ID No. 674, Seq. ID No. 676, Seq. ID No. 682, Seq. ID No. 684, Seq. ID No. 690, Seq. ID No. 702, Seq. ID No. 704, Seq. ID No. 710, Seq. ID No. 714, Seq. ID No. 730, Seq. ID No. 734, Seq. ID No. 736, Seq. ID No. 738, Seq. ID No. 742, Seq. ID No. 748, Seq. ID No. 752, Seq. ID No. 754, Seq. ID No. 760, Seq. ID No. 766, Seq. ID No. 768, Seq. ID No. 772, Seq. ID No. 782, Seq. ID No. 784, Seq. ID No. 788, Seq. ID No. 792, Seq. ID No. 796, Seq. ID No. 800, Seq. ID No. 808, Seq. ID No. 818, Seq. ID No. 820, Seq. ID No. 824, Seq. ID No. 828, Seq. ID No. 832, Seq. ID No. 836, Seq. ID No. 838, Seq. ID No. 840, Seq. ID No. 848, Seq. ID No. 852, Seq. ID No. 856, Seq. ID No. 860, Seq. ID No. 868, Seq. ID No. 872, Seq. ID No. 876, Seq. ID No. 882, Seq. ID No. 886, Seq. ID No. 890, Seq. ID No. 892, Seq. ID No. 896, Seq. ID No. 902, Seq. ID No. 908, Seq. ID No. 916, Seq. ID No. 920, Seq. ID No. 926, Seq. ID No. 930, Seq. ID No. 936, Seq. ID No. 940, Seq. ID No. 950, Seq. ID No. 952, Seq. ID No. 956, Seq. ID No. 962, Seq. ID No. 966, Seq. ID No. 968, Seq. ID No. 972, Seq. ID No. 986, Seq. ID No. 994, Seq. ID No. 998, Seq. ID No. 1004, Seq. ID No. 1006, Seq. ID No. 1010, Seq. ID No. 1018, Seq. ID No. 1024, Seq. ID No. 1040, Seq. ID No. 1042, Seq. ID No. 1044, Seq. ID No. 1052, Seq. ID No. 1054, Seq. ID No. 1058, Seq. ID No. 1062, Seq. ID No. 1066, Seq. ID No. 1068, Seq. ID No. 1070, Seq. ID No. 1074, Seq. ID No. 1076, Seq. ID No. 1084, Seq. ID No. 1088, Seq. ID No. 1092, Seq. ID No. 1094, Seq. ID No. 1098, Seq. ID No. 1100, Seq. ID No. 1104, Seq. ID No. 1110, Seq. ID No. 1116, Seq. ID No. 1118, Seq. ID No. 1124, Seq. ID No. 1130, Seq. ID No. 1134, Seq. ID No. 1138, Seq. ID No. 1144, Seq. ID No. 1148, Seq. ID No. 1150, Seq. ID No. 1156, Seq. ID No. 1158, Seq. ID No. 1160, Seq. ID No. 1164, Seq. ID No. 1172, Seq. ID No. 1180, Seq. ID No. 1182, Seq. ID No. 1188, Seq. ID No. 1194, Seq. ID No. 1200, Seq. ID No. 1206, Seq. ID No. 1212, Seq. ID No. 1218, Seq. ID No. 1222, Seq. ID No. 1224, Seq. ID No. 1226, Seq. ID No. 1232, Seq. ID No. 1234, Seq. ID No. 1238, Seq. ID No. 1242, Seq. ID No. 1254, Seq. ID No. 1258, Seq. ID No. 1264, Seq. ID No. 1272, Seq. ID No. 1282, Seq. ID No. 1318, Seq. ID No. 1324, Seq. ID No. 1332, Seq. ID No. 1336, Seq. ID No. 1340, Seq. ID No. 1346, Seq. ID No. 1348, Seq. ID No. 1362, Seq. ID No. 1370, Seq. ID No. 1378, Seq. ID No. 1380, Seq. ID No. 1388, Seq. ID No. 1394, Seq. ID No. 1396, Seq. ID No. 1400, Seq. ID No. 1404, Seq. ID No. 1406, Seq. ID No. 1412, Seq. ID No. 1414, Seq. ID No. 1416, Seq. ID No. 1420, Seq. ID No. 1426, Seq. ID No. 1428, Seq. ID No. 1430, Seq. ID No. 1432, Seq. ID No. 1434, Seq. ID No. 1438, Seq. ID No. 1444, Seq. ID No. 1450, Seq. ID No. 1452, Seq. ID No. 1456, Seq. ID No. 1458, Seq. ID No. 1460, Seq. ID No. 1464, Seq. ID No. 1466, Seq. ID No. 1470, Seq. ID No. 1472, Seq. ID No. 1474, Seq. ID No. 1476, Seq. ID No. 1478, Seq. ID No. 1486, Seq. ID No. 1488, Seq. ID No. 1492, Seq. ID No. 1494, Seq. ID No. 1496, Seq. ID No. 1498, Seq. ID No. 1502, Seq. ID No. 1506, Seq. ID No. 1508, Seq. ID No. 1510, Seq. ID No. 1518, Seq. ID No. 1526, Seq. ID No. 1528, Seq. ID No. 1532, Seq. ID No. 1540, Seq. ID No. 1542, Seq. ID No. 1544, Seq. ID No. 1550, Seq. ID No. 1562, Seq. ID No. 1564, Seq. ID No. 1568, Seq. ID No. 1572, Seq. ID No. 1574, Seq. ID No. 1578, Seq. ID No. 1582, Seq. ID No. 1590, Seq. ID No. 1594, Seq. ID No. 1596, Seq. ID No. 1598, Seq. ID No. 1604, Seq. ID No. 1608, Seq. ID No. 1612, Seq. ID No. 1614, Seq. ID No. 1620, Seq. ID No. 1624, Seq. ID No. 1628, Seq. ID No. 1632, Seq. ID No. 1638, Seq. ID No. 1640, Seq. ID No. 1642, Seq. ID No. 1648, Seq. ID No. 1654, Seq. ID No. 1658, Seq. ID No. 1666, Seq. ID No. 1670, Seq. ID No. 1682, Seq. ID No. 1686, Seq. ID No. 1690, Seq. ID No. 1692, Seq. ID No. 1698, Seq. ID No. 1700, Seq. ID No. 1708, Seq. ID No. 1712, Seq. ID No. 1714, Seq. ID No. 1720, Seq. ID No. 1724, Seq. ID No. 1730, Seq. ID No. 1736, Seq. ID No. 1738, Seq. ID No. 1742, Seq. ID No. 1748, Seq. ID No. 1752, Seq. ID No. 1758, Seq. ID No. 1760, Seq. ID No. 1762, Seq. ID No. 1772, Seq. ID No. 1778, Seq. ID No. 1786, Seq. ID No. 1790, Seq. ID No. 1792, Seq. ID No. 1798, Seq. ID No. 1802, Seq. ID No. 1804, Seq. ID No. 1806, Seq. ID No. 1812, Seq. ID No. 1818, Seq. ID No. 1820, Seq. ID No. 1822, Seq. ID No. 1826, Seq. ID No. 1830, Seq. ID No. 1838, Seq. ID No. 1844, Seq. ID No. 1846, Seq. ID No. 1848, Seq. ID No. 1850, Seq. ID No. 1852, Seq. ID No. 1856, Seq. ID No. 1860, Seq. ID No. 1864, Seq. ID No. 1866, Seq. ID No. 1868, Seq. ID No. 1872, Seq. ID No. 1874, Seq. ID No. 1878, Seq. ID No. 1886, Seq. ID No. 1888, Seq. ID No. 1890, Seq. ID No. 1896, Seq. ID No. 1898, Seq. ID No. 1900, Seq. ID No. 1904, Seq. ID No. 1906, Seq. ID No. 1914, Seq. ID No. 1920, Seq. ID No. 1924, Seq. ID No. 1926, Seq. ID No. 1932, Seq. ID No. 1936, Seq. ID No. 1938, Seq. ID No. 1944, Seq. ID No. 1946, Seq. ID No. 1950, Seq. ID No. 1954, Seq. ID No. 1958, Seq. ID No. 1960, Seq. ID No. 1962, Seq. ID No. 1966, Seq. ID No. 1968, Seq. ID No. 1972, Seq. ID No. 1976, Seq. ID No. 1980, Seq. ID No. 1984, Seq. ID No. 1988, Seq. ID No. 1990, Seq. ID No. 1992, Seq. ID No. 2000, Seq. ID No. 2002, Seq. ID No. 2004, Seq. ID No. 2010, Seq. ID No. 2016, Seq. ID No. 2020, Seq. 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ID No. 4862, Seq. ID No. 4866, Seq. ID No. 4868, Seq. ID No. 4876, Seq. ID No. 4878, Seq. ID No. 4880, Seq. ID No. 4882, Seq. ID No. 4884, Seq. ID No. 4886, Seq. ID No. 4888, Seq. ID No. 4894, Seq. ID No. 4900, Seq. ID No. 4902, Seq. ID No. 4904, Seq. ID No. 4906, Seq. ID No. 4908, Seq. ID No. 4912, Seq. ID No. 4916, Seq. ID No. 4918, Seq. ID No. 4920, Seq. ID No. 4922, Seq. ID No. 4928, Seq. ID No. 4932, Seq. ID No. 4936, Seq. ID No. 4940, Seq. ID No. 4942, Seq. ID No. 4944, Seq. ID No. 4946, Seq. ID No. 4948, Seq. ID No. 4954, Seq. ID No. 4958, Seq. ID No. 4960, Seq. ID No. 4964, Seq. ID No. 4966, Seq. ID No. 4970, Seq. ID No. 4972, Seq. ID No. 4974, Seq. ID No. 4980, Seq. ID No. 4986, Seq. ID No. 4990, Seq. ID No. 4992, Seq. ID No. 4996, Seq. ID No. 4998, Seq. ID No. 5002, Seq. ID No. 5008, Seq. ID No. 5010, Seq. ID No. 5018, Seq. ID No. 5022, Seq. ID No. 5028, Seq. ID No. 5030, Seq. ID No. 5040, Seq. ID No. 5048, Seq. ID No. 5052, Seq. ID No. 5054, Seq. ID No. 5056, Seq. ID No. 5060, Seq. ID No. 5062, Seq. ID No. 5070, Seq. ID No. 5078, Seq. ID No. 5080, Seq. ID No. 5082, Seq. ID No. 5084, Seq. ID No. 5088, Seq. ID No. 5092, Seq. ID No. 5094, Seq. ID No. 5098, Seq. ID No. 5104, Seq. ID No. 5106, Seq. ID No. 5110, Seq. ID No. 5112, Seq. ID No. 5114, Seq. ID No. 5116, Seq. ID No. 5118, Seq. ID No. 5128, Seq. ID No. 5142, Seq. ID No. 5146, Seq. ID No. 5150, Seq. ID No. 5154, Seq. ID No. 5158, Seq. ID No. 5166, Seq. ID No. 5170, Seq. ID No. 5172, Seq. ID No. 5178, Seq. ID No. 5184, Seq. ID No. 5186, Seq. ID No. 5188, Seq. ID No. 5194, Seq. ID No. 5196, Seq. ID No. 5202, Seq. ID No. 5204, Seq. ID No. 5206, Seq. ID No. 5210, Seq. ID No. 5212, Seq. ID No. 5216, Seq. ID No. 5220, Seq. ID No. 5228, Seq. ID No. 5232, Seq. ID No. 5236, Seq. ID No. 5238, Seq. ID No. 5240, Seq. ID No. 5244, Seq. ID No. 5246, Seq. ID No. 5248, Seq. ID No. 5254, Seq. ID No. 5256, Seq. ID No. 5258, Seq. ID No. 5262, Seq. ID No. 5264, Seq. ID No. 5272, Seq. ID No. 5276, Seq. ID No. 5284, Seq. ID No. 5292, Seq. ID No. 5300, Seq. ID No. 5306, Seq. ID No. 5310, Seq. ID No. 5312, Seq. ID No. 5314, Seq. ID No. 5320, Seq. ID No. 5324, Seq. ID No. 5326, Seq. ID No. 5336, Seq. ID No. 5338, Seq. ID No. 5342, Seq. ID No. 5346, Seq. ID No. 5352, Seq. ID No. 5356, Seq. ID No. 5364, Seq. ID No. 5366, Seq. ID No. 5368, Seq. ID No. 5372, Seq. ID No. 5374, Seq. ID No. 5382, Seq. ID No. 5384, Seq. ID No. 5388, Seq. ID No. 5390, Seq. ID No. 5392, Seq. ID No. 5394, Seq. ID No. 5396, Seq. ID No. 5398, Seq. ID No. 5400, Seq. ID No. 5402, Seq. ID No. 5404, Seq. ID No. 5410, Seq. ID No. 5412, Seq. ID No. 5416, Seq. ID No. 5418, Seq. ID No. 5420, Seq. ID No. 5422, Seq. ID No. 5424, Seq. ID No. 5428, Seq. ID No. 5432, Seq. ID No. 5434, Seq. ID No. 5440, Seq. ID No. 5442, Seq. ID No. 5444, Seq. ID No. 5448, Seq. ID No. 5450, Seq. ID No. 5452, Seq. ID No. 5454, Seq. ID No. 5456, Seq. ID No. 5458, Seq. ID No. 5474, Seq. ID No. 5478, Seq. ID No. 5484, Seq. ID No. 5488, Seq. ID No. 5492, Seq. ID No. 5496, Seq. ID No. 5500, Seq. ID No. 5504, Seq. ID No. 5508, Seq. ID No. 5510, Seq. ID No. 5514, Seq. ID No. 5528, Seq. ID No. 5532, Seq. ID No. 5538, Seq. ID No. 5540, Seq. ID No. 5542, Seq. ID No. 5548, Seq. ID No. 5554, Seq. ID No. 5558, Seq. ID No. 5560, Seq. ID No. 5564, Seq. ID No. 5568, Seq. ID No. 5572, Seq. ID No. 5576, Seq. ID No. 5582, Seq. ID No. 5586, Seq. ID No. 5592, Seq. ID No. 5600, Seq. ID No. 5602, Seq. ID No. 5606, Seq. ID No. 5616, Seq. ID No. 5622, Seq. ID No. 5630, Seq. ID No. 5632, Seq. ID No. 5638, Seq. ID No. 5648, Seq. ID No. 5652, Seq. ID No. 5656, Seq. ID No. 5658, Seq. ID No. 5662, Seq. ID No. 5666, Seq. ID No. 5670, Seq. ID No. 5672, Seq. ID No. 5674, Seq. ID No. 5680, Seq. ID No. 5686, Seq. ID No. 5694, Seq. ID No. 5698, Seq. ID No. 5700, Seq. ID No. 5702, Seq. ID No. 5708, Seq. ID No. 5716, Seq. ID No. 5718, Seq. ID No. 5724, Seq. ID No. 5728, Seq. ID No. 5736, Seq. ID No. 5740, Seq. ID No. 5750, Seq. ID No. 5752, Seq. ID No. 5756, Seq. ID No. 5762, Seq. ID No. 5772, Seq. ID No. 5776, Seq. ID No. 5778, Seq. ID No. 5780, Seq. ID No. 5784, Seq. ID No. 5790, Seq. ID No. 5796, Seq. ID No. 5802, Seq. ID No. 5804, Seq. ID No. 5810, Seq. ID No. 5816, Seq. ID No. 5820, Seq. ID No. 5826, Seq. ID No. 5834, Seq. ID No. 5836, Seq. ID No. 5842, Seq. ID No. 5846, Seq. ID No. 5848, Seq. ID No. 5850, Seq. ID No. 5852, Seq. ID No. 5854, Seq. ID No. 5856, Seq. ID No. 5860, Seq. ID No. 5866, Seq. ID No. 5872, Seq. ID No. 5876, Seq. ID No. 5878, Seq. ID No. 5882, Seq. ID No. 5888, Seq. ID No. 5892, Seq. ID No. 5896, Seq. ID No. 5898, Seq. ID No. 5902, Seq. ID No. 5904, Seq. ID No. 5912, Seq. ID No. 5914, Seq. ID No. 5916, Seq. ID No. 5918, Seq. ID No. 5920, Seq. ID No. 5930, Seq. ID No. 5932, Seq. ID No. 5934, Seq. ID No. 5938, Seq. ID No. 5942, Seq. ID No. 5944, Seq. ID No. 5948, Seq. ID No. 5952, Seq. ID No. 5954, Seq. ID No. 5956, Seq. ID No. 5958, Seq. ID No. 5962, Seq. ID No. 5970, Seq. ID No. 5974, Seq. ID No. 5980, Seq. ID No. 5982, Seq. ID No. 5986, Seq. ID No. 5990, Seq. ID No. 5994, Seq. ID No. 6002, Seq. ID No. 6004, Seq. ID No. 6012, Seq. ID No. 6016, Seq. ID No. 6018, Seq. ID No. 6022, Seq. ID No. 6028, Seq. ID No. 6030, Seq. ID No. 6034, Seq. ID No. 6036, Seq. ID No. 6042, Seq. ID No. 6044, Seq. ID No. 6054, Seq. ID No. 6058, Seq. ID No. 6066, Seq. ID No. 6072, Seq. ID No. 6080, Seq. ID No. 6086, Seq. ID No. 6090, Seq. ID No. 6096, Seq. ID No. 6098, Seq. ID No. 6102, Seq. ID No. 6104, Seq. ID No. 6112, Seq. ID No. 6114, Seq. ID No. 6118, Seq. ID No. 6124, Seq. ID No. 6126, Seq. ID No. 6130, Seq. ID No. 6132, Seq. ID No. 6134, Seq. ID No. 6142, Seq. ID No. 6146, Seq. ID No. 6150, Seq. ID No. 6158, Seq. ID No. 6166, Seq. ID No. 6170, Seq. ID No. 6172, Seq. ID No. 6176, Seq. ID No. 6178, Seq. ID No. 6182, Seq. ID No. 6188, Seq. ID No. 6196, Seq. ID No. 6202, Seq. ID No. 6210, Seq. ID No. 6214, Seq. ID No. 6216, Seq. ID No. 6220, Seq. ID No. 6234, Seq. ID No. 6236, Seq. ID No. 6244, Seq. ID No. 6250, Seq. ID No. 6252, Seq. ID No. 6258, Seq. ID No. 6262, Seq. ID No. 6264, Seq. ID No. 6272, Seq. ID No. 6276, Seq. ID No. 6278, Seq. ID No. 6282, Seq. ID No. 6288, Seq. ID No. 6298, Seq. ID No. 6300, Seq. ID No. 6306, Seq. ID No. 6312, Seq. ID No. 6316, Seq. ID No. 6322, Seq. ID No. 6324, Seq. ID No. 6328, Seq. ID No. 6332, Seq. ID No. 6334, Seq. ID No. 6338, Seq. ID No. 6340, Seq. ID No. 6342, Seq. ID No. 6344, Seq. ID No. 6346, Seq. ID No. 6354, Seq. ID No. 6358, Seq. ID No. 6360, Seq. ID No. 6362, Seq. ID No. 6368, Seq. ID No. 6370, Seq. ID No. 6374, Seq. ID No. 6376, Seq. ID No. 6378, Seq. ID No. 6380, Seq. ID No. 6390, Seq. ID No. 6396, Seq. ID No. 6400, Seq. ID No. 6404, Seq. ID No. 6408, Seq. ID No. 6412, Seq. ID No. 6414, Seq. ID No. 6418, Seq. ID No. 6424, Seq. ID No. 6434, Seq. ID No. 6438, Seq. ID No. 6440, Seq. ID No. 6446, Seq. ID No. 6450, Seq. ID No. 6452, Seq. ID No. 6458, Seq. ID No. 6460, Seq. ID No. 6462, Seq. ID No. 6464, Seq. ID No. 6478, Seq. ID No. 6482, Seq. ID No. 6484, Seq. ID No. 6488, Seq. ID No. 6490, Seq. ID No. 6492, Seq. ID No. 6494, Seq. ID No. 6496, Seq. ID No. 6504, Seq. ID No. 6506, Seq. ID No. 6512, Seq. ID No. 6516, Seq. ID No. 6520, Seq. ID No. 6524, Seq. ID No. 6526, Seq. ID No. 6530, Seq. ID No. 6532, Seq. ID No. 6534, Seq. ID No. 6538, Seq. ID No. 6546, Seq. ID No. 6552, Seq. ID No. 6554, Seq. ID No. 6560, Seq. ID No. 6564, Seq. ID No. 6568, Seq. ID No. 6578, Seq. ID No. 6580, Seq. ID No. 6584, Seq. ID No. 6586, Seq. ID No. 6588, Seq. ID No. 6590, Seq. ID No. 6604, Seq. ID No. 6606, Seq. ID No. 6610, Seq. ID No. 6614, Seq. ID No. 6616, Seq. ID No. 6618, Seq. ID No. 6622, Seq. ID No. 6624, Seq. ID No. 6628, Seq. ID No. 6630, Seq. ID No. 6634, and Seq. ID No.
 6640. 53. The Alloiococcus otitidis polypeptide of claim 36 wherein the polypeptide is identified as an Alloiococcus otitidis polypeptide by GeneMark™ ORF finder program, and is selected from one of Seq. ID No. 2, Seq. ID No. 4, Seq. ID No. 12, Seq. ID No. 14, Seq. ID No. 16, Seq. ID No. 18, Seq. ID No. 26, Seq. ID No. 28, Seq. ID No. 30, Seq. ID No. 36, Seq. ID No. 38, Seq. ID No. 40, Seq. ID No. 42, Seq. ID No. 44, Seq. ID No. 46, Seq. ID No. 50, Seq. ID No. 54, Seq. ID No. 58, Seq. ID No. 62, Seq. ID No. 70, Seq. ID No. 72, Seq. ID No. 76, Seq. ID No. 82, Seq. ID No. 84, Seq. ID No. 90, Seq. ID No. 96, Seq. ID No. 102, Seq. ID No. 112, Seq. ID No. 120, Seq. ID No. 126, Seq. ID No. 130, Seq. ID No. 136, Seq. ID No. 138, Seq. ID No. 142, Seq. ID No. 148, Seq. ID No. 152, Seq. ID No. 156, Seq. ID No. 168, Seq. ID No. 172, Seq. ID No. 182, Seq. ID No. 186, Seq. ID No. 188, Seq. ID No. 190, Seq. ID No. 192, Seq. ID No. 196, Seq. ID No. 200, Seq. ID No. 208, Seq. ID No. 214, Seq. ID No. 220, Seq. ID No. 222, Seq. ID No. 226, Seq. ID No. 228, Seq. ID No. 230, Seq. ID No. 234, Seq. ID No. 240, Seq. ID No. 242, Seq. ID No. 244, Seq. ID No. 254, Seq. ID No. 262, Seq. ID No. 264, Seq. ID No. 268, Seq. ID No. 274, Seq. ID No. 276, Seq. ID No. 278, Seq. ID No. 280, Seq. ID No. 292, Seq. ID No. 294, Seq. ID No. 296, Seq. ID No. 300, Seq. ID No. 304, Seq. ID No. 310, Seq. ID No. 312, Seq. ID No. 316, Seq. ID No. 320, Seq. ID No. 324, Seq. ID No. 332, Seq. ID No. 342, Seq. ID No. 346, Seq. ID No. 352, Seq. ID No. 356, Seq. ID No. 362, Seq. ID No. 364, Seq. ID No. 366, Seq. ID No. 376, Seq. ID No. 380, Seq. ID No. 382, Seq. ID No. 384, Seq. ID No. 390, Seq. ID No. 392, Seq. ID No. 396, Seq. ID No. 400, Seq. ID No. 406, Seq. ID No. 410, Seq. ID No. 414, Seq. ID No. 418, Seq. ID No. 422, Seq. ID No. 424, Seq. ID No. 426, Seq. ID No. 428, Seq. ID No. 430, Seq. ID No. 436, Seq. ID No. 438, Seq. ID No. 440, Seq. ID No. 442, Seq. ID No. 444, Seq. ID No. 446, Seq. ID No. 448, Seq. ID No. 450, Seq. ID No. 460, Seq. ID No. 466, Seq. ID No. 486, Seq. ID No. 502, Seq. ID No. 506, Seq. ID No. 512, Seq. ID No. 514, Seq. ID No. 518, Seq. ID No. 520, Seq. ID No. 524, Seq. ID No. 530, Seq. ID No. 534, Seq. ID No. 536, Seq. ID No. 542, Seq. ID No. 544, Seq. ID No. 552, Seq. ID No. 554, Seq. ID No. 560, Seq. ID No. 564, Seq. ID No. 570, Seq. ID No. 576, Seq. ID No. 580, Seq. ID No. 584, Seq. ID No. 592, Seq. ID No. 596, Seq. ID No. 602, Seq. ID No. 606, Seq. ID No. 608, Seq. ID No. 612, Seq. ID No. 614, Seq. ID No. 616, Seq. ID No. 622, Seq. ID No. 628, Seq. ID No. 630, Seq. ID No. 634, Seq. ID No. 636, Seq. ID No. 638, Seq. ID No. 644, Seq. ID No. 650, Seq. ID No. 652, Seq. ID No. 656, Seq. ID No. 658, Seq. ID No. 670, Seq. ID No. 672, Seq. ID No. 676, Seq. ID No. 682, Seq. ID No. 684, Seq. ID No. 686, Seq. ID No. 694, Seq. ID No. 704, Seq. ID No. 706, Seq. ID No. 712, Seq. ID No.;726, Seq. ID No. 732, Seq. ID No. 736, Seq. ID No. 738, Seq. ID No. 742, Seq. ID No. 744, Seq. ID No. 750, Seq. ID No. 754, Seq. ID No. 760, Seq. ID No. 774, Seq. ID No. 782, Seq. ID No. 784, Seq. ID No. 786, Seq. ID No. 790, Seq. ID No. 794, Seq. ID No. 798, Seq. ID No. 804, Seq. ID No. 816, Seq. ID No. 820, Seq. ID No. 822, Seq. ID No. 828, Seq. ID No. 832, Seq. ID No. 834, Seq. ID No. 836, Seq. ID No. 838, Seq. ID No. 842, Seq. ID No. 844, Seq. ID No. 850, Seq. ID No. 852, Seq. ID No. 854, Seq. ID No. 858, Seq. ID No. 866, Seq. ID No. 870, Seq. ID No. 874, Seq. ID No. 878, Seq. ID No. 884, Seq. ID No. 888, Seq. ID No. 892, Seq. ID No. 896, Seq. ID No. 902, Seq. ID No. 908, Seq. ID No. 912, Seq. ID No. 918, Seq. ID No. 922, Seq. ID No. 928, Seq. ID No. 936, Seq. ID No. 940, Seq. ID No. 946, Seq. ID No. 952, Seq. ID No. 954, Seq. ID No. 960, Seq. ID No. 964, Seq. ID No. 968, Seq. ID No. 970, Seq. ID No. 978, Seq. ID No. 990, Seq. ID No. 996, Seq. ID No. 1000, Seq. ID No. 1006, Seq. ID No. 1008, Seq. ID No. 1016, Seq. ID No. 1022, Seq. ID No. 1036, Seq. ID No. 1042, Seq. ID No. 1044, Seq. ID No. 1050, Seq. ID No. 1054, Seq. ID No. 1058, Seq. ID No. 1060, Seq. ID No. 1064, Seq. ID No. 1068, Seq. ID No. 1070, Seq. ID No. 1072, Seq. ID No. 1076, Seq. ID No. 1084, Seq. ID No. 1086, Seq. ID No. 1090, Seq. ID No. 1094, Seq. ID No. 1098, Seq. ID No. 1100, Seq. ID No. 1102, Seq. ID No. 1110, Seq. ID No. 1114, Seq. ID No. 1118, Seq. ID No. 1122, Seq. ID No. 1130, Seq. ID No. 1134, Seq. ID No. 1138, Seq. ID No. 1142, Seq. ID No. 1146, Seq. ID No. 1150, Seq. ID No. 1156, Seq. ID No. 1158, Seq. ID No. 1160, Seq. ID No. 1164, Seq. ID No. 1172, Seq. ID No. 1174, Seq. ID No. 1176, Seq. ID No. 1182, Seq. ID No. 1186, Seq. ID No. 1190, Seq. ID No. 1200, Seq. ID No. 1206, Seq. ID No. 1210, Seq. ID No. 1216, Seq. ID No. 1220, Seq. ID No. 1224, Seq. ID No. 1226, Seq. ID No. 1234, Seq. ID No. 1236, Seq. ID No. 1242, Seq. ID No. 1252, Seq. ID No. 1256, Seq. ID No. 1262, Seq. ID No. 1272, Seq. ID No. 1282, Seq. ID No. 1316, Seq. ID No. 1324, Seq. ID No. 1332, Seq. ID No. 1334, Seq. ID No. 1340, Seq. ID No. 1346, Seq. ID No. 1348, Seq. ID No. 1356, Seq. ID No. 1358, Seq. ID No. 1370, Seq. ID No. 1374, Seq. ID No. 1388, Seq. ID No. 1392, Seq. ID No. 1396, Seq. ID No. 1398, Seq. ID No. 1404, Seq. ID No. 1406, Seq. ID No. 1408, Seq. ID No. 1414, Seq. ID No. 1416, Seq. ID No. 1418, Seq. ID No. 1426, Seq. ID No. 1428, Seq. ID No. 1430, Seq. ID No. 1432, Seq. ID No. 1434, Seq. ID No. 1436, Seq. ID No. 1440, Seq. ID No. 1442, Seq. ID No. 1452, Seq. ID No. 1454, Seq. ID No. 1460, Seq. ID No. 1462, Seq. ID No. 1470, Seq. ID No. 1472, Seq. ID No. 1474, Seq. ID No. 1476, Seq. ID No. 1478, Seq. ID No. 1484, Seq. ID No. 1488, Seq. ID No. 1490, Seq. ID No. 1494, Seq. ID No. 1496, Seq. ID No. 1498, Seq. ID No. 1502, Seq. ID No. 1504, Seq. ID No. 1508, Seq. ID No. 1510, Seq. ID No. 1518, Seq. ID No. 1522, Seq. ID No. 1528, Seq. ID No. 1532, Seq. ID No. 1538, Seq. ID No. 1542, Seq. ID No. 1544, Seq. ID No. 1550, Seq. ID No. 1562, Seq. ID No. 1564, Seq. ID No. 1566, Seq. ID No. 1570, Seq. ID No. 1574, Seq. ID No. 1576, Seq. ID No. 1582, Seq. ID No. 1588, Seq. ID No. 1592, Seq. ID No. 1596, Seq. ID No. 1598, Seq. ID No. 1606, Seq. ID No. 1610, Seq. ID No. 1614, Seq. ID No. 1620, Seq. ID No. 1624, Seq. ID No. 1628, Seq. ID No. 1630, Seq. ID No. 1636, Seq. ID No. 1642, Seq. ID No. 1648, Seq. ID No. 1652, Seq. ID No. 1658, Seq. ID No. 1660, Seq. ID No. 1668, Seq. ID No. 1670, Seq. ID No. 1680, Seq. ID No. 1684, Seq. ID No. 1688, Seq. ID No. 1692, Seq. ID No. 1698, Seq. ID No. 1700, Seq. ID No. 1702, Seq. ID No. 1708, Seq. ID No. 1710, Seq. ID No. 1714, Seq. ID No. 1718, Seq. ID No. 1722, Seq. ID No. 1726, Seq. ID No. 1736, Seq. ID No. 1738, Seq. ID No. 1740, Seq. ID No. 1744, Seq. ID No. 1746, Seq. ID No. 1750, Seq. ID No. 1756, Seq. ID No. 1770, Seq. ID No. 1774, Seq. ID No. 1778, Seq. ID No. 1786, Seq. ID No. 1790, Seq. ID No. 1792, Seq. ID No. 1798, Seq. ID No. 1800, Seq. ID No. 1804, Seq. ID No. 1806, Seq. ID No. 1808, Seq. ID No. 1818, Seq. ID No. 1820, Seq. ID No. 1822, Seq. ID No. 1826, Seq. ID No. 1828, Seq. ID No. 1832, Seq. ID No.-1836, Seq. ID No. 1842, Seq. ID No. 1846, Seq. ID No. 1848, Seq. ID No. 1850, Seq. ID No. 1852, Seq. ID No. 1856, Seq. ID No. 1860, Seq. ID No. 1862, Seq. ID No. 1866, Seq. ID No. 1868, Seq. ID No. 1872, Seq. ID No. 1874, Seq. ID No. 1878, Seq. ID No. 1880, Seq. ID No. 1888, Seq. ID No. 1890, Seq. ID No. 1896, Seq. ID No. 1898, Seq. ID No. 1900, Seq. ID No. 1902, Seq. ID No. 1906, Seq. ID No. 1910, Seq. ID No. 1918, Seq. ID No. 1922, Seq. ID No. 1926, Seq. ID No. 1932, Seq. ID No. 1934, Seq. ID No. 1938, Seq. ID No. 1940, Seq. ID No. 1946, Seq. ID No. 1948, Seq. ID No. 1952, Seq. ID No. 1956, Seq. ID No. 1960, Seq. ID No. 1962, Seq. ID No. 1966, Seq. ID No. 1968, Seq. ID No. 1970, Seq. ID No. 1974, Seq. ID No. 1978, Seq. ID No. 1980, Seq. ID No. 1984, Seq. ID No. 1990, Seq. ID No. 1992, Seq. ID No. 1998, Seq. ID No. 2002, Seq. 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ID No. 4876, Seq. ID No. 4880, Seq. ID No. 4882, Seq. ID No. 4884, Seq. ID No. 4886, Seq. ID No. 4888, Seq. ID No. 4894, Seq. ID No. 4900, Seq. ID No. 4902, Seq. ID No. 4904, Seq. ID No. 4906, Seq. ID No. 4908, Seq. ID No. 4910, Seq. ID No. 4916, Seq. ID No. 4918, Seq. ID No. 4920, Seq. ID No. 4922, Seq. ID No. 4926, Seq. ID No. 4930, Seq. ID No. 4934, Seq. ID No. 4938, Seq. ID No. 4942, Seq. ID No. 4944, Seq. ID No. 4946, Seq. ID No. 4948, Seq. ID No. 4954, Seq. ID No. 4956, Seq. ID No. 4960, Seq. ID No. 4962, Seq. ID No. 4966, Seq. ID No. 4968, Seq. ID No. 4972, Seq. ID No. 4974, Seq. ID No. 4978, Seq. ID No. 4986, Seq. ID No. 4990, Seq. ID No. 4992, Seq. ID No. 4996, Seq. ID No. 4998, Seq. ID No. 5006, Seq. ID No. 5010, Seq. ID No. 5016, Seq. ID No. 5020, Seq. ID No. 5026, Seq. ID No. 5030, Seq. ID No. 5038, Seq. ID No. 5046, Seq. ID No. 5050, Seq. ID No. 5054, Seq. ID No. 5056, Seq. ID No. 5060, Seq. ID No. 5062, Seq. ID No. 5066, Seq. ID No. 5072, Seq. ID No. 5074, Seq. ID No. 5080, Seq. ID No. 5082, Seq. ID No. 5084, Seq. ID No. 5088, Seq. ID No. 5090, Seq. ID No. 5094, Seq. ID No. 5096, Seq. ID No. 5104, Seq. ID No. 5106, Seq. ID No. 5108, Seq. ID No. 5112, Seq. ID No. 5114, Seq. ID No. 5116, Seq. ID No. 5118, Seq. ID No. 5120, Seq. ID No. 5142, Seq. ID No. 5144, Seq. ID No. 5148, Seq. ID No. 5154, Seq. ID No. 5156, Seq. ID No. 5164, Seq. ID No. 5170, Seq. ID No. 5172, Seq. ID No. 5174, Seq. ID No. 5180, Seq. ID No. 5186, Seq. ID No. 5188, Seq. ID No. 5194, Seq. ID No. 5196, Seq. ID No. 5202, Seq. ID No. 5204, Seq. ID No. 5206, Seq. ID No. 5210, Seq. ID No. 5212, Seq. ID No. 5214, Seq. ID No. 5218, Seq. ID No. 5226, Seq. ID No. 5232, Seq. ID No. 5234, Seq. ID No. 5238, Seq. ID No. 5240, Seq. ID No. 5246, Seq. ID No. 5248, Seq. ID No. 5250, Seq. ID No. 5256, Seq. ID No. 5258, Seq. ID No. 5260, Seq. ID No. 5264, Seq. ID No. 5270, Seq. ID No. 5274, Seq. ID No. 5284, Seq. ID No. 5290, Seq. ID No. 5294, Seq. ID No. 5308, Seq. ID No. 5312, Seq. ID No. 5314, Seq. ID No. 5316, Seq. ID No. 5324, Seq. ID No. 5326, Seq. ID No. 5336, Seq. ID No. 5338, Seq. ID No. 5340, Seq. ID No. 5346, Seq. ID No. 5348, Seq. ID No. 5350, Seq. ID No. 5354, Seq. ID No. 5362, Seq. ID No. 5366, Seq. ID No. 5368, Seq. ID No. 5370, Seq. ID No. 5374, Seq. ID No. 5376, Seq. ID No. 5388, Seq. ID No. 5390, Seq. ID No. 5392, Seq. ID No. 5394, Seq. ID No. 5396, Seq. ID No. 5398, Seq. ID No. 5400, Seq. ID No. 5402, Seq. ID No. 5404, Seq. ID No. 5406, Seq. ID No. 5412, Seq. ID No. 5416, Seq. ID No. 5418, Seq. ID No. 5420, Seq. ID No. 5422, Seq. ID No. 5424, Seq. ID No. 5430, Seq. ID No. 5434, Seq. ID No. 5442, Seq. ID No. 5444, Seq. ID No. 5446, Seq. ID No. 5450, Seq. ID No. 5452, Seq. ID No. 5454, Seq. ID No. 5456, Seq. ID No. 5458, Seq. ID No. 5470, Seq. ID No. 5476, Seq. ID No. 5484, Seq. ID No. 5486, Seq. ID No. 5490, Seq. ID No. 5494, Seq. ID No. 5500, Seq. ID No. 5502, Seq. ID No. 5506, Seq. ID No. 5510, Seq. ID No. 5512, Seq. ID No. 5524, Seq. ID No. 5530, Seq. ID No. 5536, Seq. ID No. 5540, Seq. ID No. 5542, Seq. ID No. 5548, Seq. ID No. 5552, Seq. ID No. 5556, Seq. ID No. 5560, Seq. ID No. 5562, Seq. ID No. 5566, Seq. ID No. 5572, Seq. ID No. 5574, Seq. ID No. 5580, Seq. ID No. 5584, Seq. ID No. 5590, Seq. ID No. 5600, Seq. ID No. 5602, Seq. ID No. 5604, Seq. ID No. 5614, Seq. ID No. 5622, Seq. ID No. 5628, Seq. ID No. 5632, Seq. ID No. 5636, Seq. ID No. 5646, Seq. ID No. 5652, Seq. ID No. 5654, Seq. ID No. 5658, Seq. ID No. 5662, Seq. ID No. 5664, Seq. ID No. 5666, Seq. ID No. 5670, Seq. ID No. 5672, Seq. ID No. 5674, Seq. ID No. 5676, Seq. ID No. 5682, Seq. ID No. 5694, Seq. ID No. 5696, Seq. ID No. 5700, Seq. ID No. 5702, Seq. ID No. 5708, Seq. ID No. 5714, Seq. ID No. 5718, Seq. ID No. 5724, Seq. ID No. 5726, Seq. ID No. 5732, Seq. ID No. 5738, Seq. ID No. 5748, Seq. ID No. 5752, Seq. ID No. 5756, Seq. ID No. 5760, Seq. ID No. 5772, Seq. ID No. 5774, Seq. ID No. 5778, Seq. ID No. 5780, Seq. ID No. 5782, Seq. ID No. 5786, Seq. ID No. 5794, Seq. ID No. 5800, Seq. ID No. 5806, Seq. ID No. 5812, Seq. ID No. 5816, Seq. ID No. 5818, Seq. ID No. 5824, Seq. ID No. 5832, Seq. ID No. 5836, Seq. ID No. 5840, Seq. ID No. 5844, Seq. ID No. 5848, Seq. ID No. 5850, Seq. ID No. 5852, Seq. ID No. 5854, Seq. ID No. 5856, Seq. ID No. 5858, Seq. ID No. 5862, Seq. ID No. 5868, Seq. ID No. 5876, Seq. ID No. 5878, Seq. ID No. 5882, Seq. ID No. 5890, Seq. ID No. 5896, Seq. ID No. 5898, Seq. ID No. 5902, Seq. ID No. 5904, Seq. ID No. 5908, Seq. ID No. 5914, Seq. ID No. 5916, Seq. ID No. 5918, Seq. ID No. 5920, Seq. ID No. 5926, Seq. ID No. 5932, Seq. ID No. 5934, Seq. ID No. 5936, Seq. ID No. 5942, Seq. ID No. 5944, Seq. ID No. 5946, Seq. ID No. 5950, Seq. ID No. 5956, Seq. ID No. 5958, Seq. ID No. 5960, Seq. ID No. 5968, Seq. ID No. 5972, Seq. ID No. 5976, Seq. ID No. 5978, Seq. ID No. 5982, Seq. ID No. 5984, Seq. ID No. 5986, Seq. ID No. 5990, Seq. ID No. 5992, Seq. ID No. 5996, Seq. ID No. 5998, Seq. ID No. 6004, Seq. ID No. 6006, Seq. ID No. 6008, Seq. ID No. 6016, Seq. ID No. 6018, Seq. ID No. 6020, Seq. ID No. 6024, Seq. ID No. 6030, Seq. ID No. 6034, Seq. ID No. 6036, Seq. ID No. 6038, Seq. ID No. 6044, Seq. ID No. 6050, Seq. ID No. 6056, Seq. ID No. 6066, Seq. ID No. 6070, Seq. ID No. 6076, Seq-. ID No. 6082, Seq. ID No. 6084, Seq. ID No. 6088, Seq. ID No. 6096, Seq. ID No. 6098, Seq. ID No. 6100, Seq. ID No. 6104, Seq. ID No. 6106, Seq. ID No. 6114, Seq. ID No. 6116, Seq. ID No. 6120, Seq. ID No. 6126, Seq. ID No. 6128, Seq. ID No. 6130, Seq. ID No. 6132, Seq. ID No. 6134, Seq. ID No. 6142, Seq. ID No. 6144, Seq. ID No. 6148, Seq. ID No. 6154, Seq. ID No. 6166, Seq. ID No. 6170, Seq. ID No. 6172, Seq. ID No. 6174, Seq. ID No. 6178, Seq. ID No. 6180, Seq. ID No. 6188, Seq. ID No. 6194, Seq. ID No. 6202, Seq. ID No. 6208, Seq. ID No. 6212, Seq. ID No. 6216, Seq. ID No. 6220, Seq. ID No. 6232, Seq. ID No. 6236, Seq. ID No. 6244, Seq. ID No. 6248, Seq. ID No. 6252, Seq. ID No. 6256, Seq. ID No. 6262, Seq. ID No. 6264, Seq. ID No. 6270, Seq. ID No. 6276, Seq. ID No. 6278, Seq. ID No. 6280, Seq. ID No. 6288, Seq. ID No. 6292, Seq. ID No. 6300, Seq. ID No. 6306, Seq. ID No. 6308, Seq. ID No. 6314, Seq. ID No. 6316, Seq. ID No. 6322, Seq. ID No. 6324, Seq. ID No. 6326, Seq. ID No. 6332, Seq. ID No. 6336, Seq. ID No. 6340, Seq. ID No. 6342, Seq. ID No. 6344, Seq. ID No. 6346, Seq. ID No. 6348, Seq. ID No. 6356, Seq. ID No. 6360, Seq. ID No. 6362, Seq. ID No. 6366, Seq. ID No. 6370, Seq. ID No. 6372, Seq. ID No. 6376, Seq. ID No. 6378, Seq. ID No. 6380, Seq. ID No. 6388, Seq. ID No. 6392, Seq. ID No. 6398, Seq. ID No. 6402, Seq. ID No. 6406, Seq. ID No. 6410, Seq. ID No. 6414, Seq. ID No. 6418, Seq. ID No. 6420, Seq. ID No. 6424, Seq. ID No. 6430, Seq. ID No. 6434, Seq. ID No. 6436, Seq. ID No. 6440, Seq. ID No. 6446, Seq. ID No. 6448, Seq. ID No. 6452, Seq. ID No. 6456, Seq. ID No. 6460, Seq. ID No. 6462, Seq. ID No. 6464, Seq. ID No. 6476, Seq. ID No. 6482, Seq. ID No. 6484, Seq. ID No. 6486, Seq. ID No. 6488, Seq. ID No. 6490, Seq. ID No. 6492, Seq. ID No. 6494, Seq. ID No. 6496, Seq. ID No. 6500, Seq. ID No. 6506, Seq. ID No. 6510, Seq. ID No. 6514, Seq. ID No. 6520, Seq. ID No. 6522, Seq. ID No. 6526, Seq. ID No. 6528, Seq. ID No. 6532, Seq. ID No. 6534, Seq. ID No. 6536, Seq. ID No. 6546, Seq. ID No. 6552, Seq. ID No. 6554, Seq. ID No. 6560, Seq. ID No. 6562, Seq. ID No. 6564, Seq. ID No. 6566, Seq. ID No. 6568, Seq. ID No. 6570, Seq. ID No. 6576, Seq. ID No. 6580, Seq. ID No. 6584, Seq. ID No. 6586, Seq. ID No. 6592, Seq. ID No. 6596, Seq. ID No. 6606, Seq. ID No. 6608, Seq. ID No. 6612, Seq. ID No. 6616, Seq. ID No. 6618, Seq. ID No. 6620, Seq. ID No. 6624, Seq. ID No. 6626, Seq. ID No. 6630, Seq. ID No. 6634, Seq. ID No. 6636, Seq. ID No. 6642, and Seq. ID No.
 6648. 54. The Alloiococcus otitidis polypeptide of claim 36, wherein the polypeptide is identified as an Alloiococcus otitidis polypeptide identified by an ORF finder program that searches for an ATG, GTG or TTG start codon between a Stop-Stop region, and is selected from one of Seq. ID No. 2, Seq. ID No. 6, Seq. ID No. 12, Seq. ID No. 14, Seq. ID No. 16, Seq. ID No. 18, Seq. ID No. 20, Seq. ID No. 22, Seq. ID No. 24, Seq. ID No. 28, Seq. ID No. 30, Seq. ID No. 32, Seq. ID No. 36, Seq. ID No. 38, Seq. ID No. 42, Seq. ID No. 44, Seq. ID No. 46, Seq. ID No. 48, Seq. ID No. 50, Seq. ID No. 52, Seq. ID No. 54, Seq. ID No. 56, Seq. ID No. 58, Seq. ID No. 60, Seq. ID No. 66, Seq. ID No. 68, Seq. ID No. 76, Seq. ID No. 78, Seq. ID No. 80, Seq. ID No. 82, Seq. ID No. 84, Seq. ID No. 90, Seq. ID No. 92, Seq. ID No. 94, Seq. ID No. 98, Seq. ID No. 100, Seq. ID No. 104, Seq. ID No. 106, Seq. ID No. 108, Seq. ID No. 110, Seq. ID No. 112, Seq. ID No. 114, Seq. ID No. 116, Seq. ID No. 118, Seq. ID No. 120, Seq. ID No. 122, Seq. ID No. 128, Seq. ID No. 130, Seq. ID No. 132, Seq. ID No. 134, Seq. ID No. 136, Seq. ID No. 138, Seq. ID No. 140, Seq. ID No. 144, Seq. ID No. 146, Seq. ID No. 148, Seq. ID No. 150, Seq. ID No. 154, Seq. ID No. 156, Seq. ID No. 158, Seq. ID No. 160, Seq. ID No. 162, Seq. ID No. 164, Seq. ID No. 166, Seq. ID No. 168, Seq. ID No. 170, Seq. ID No. 172, Seq. ID No. 176, Seq. ID No. 178, Seq. ID No. 180, Seq. ID No. 182, Seq. ID No. 184, Seq. ID No. 188, Seq. ID No. 192, Seq. ID No. 194, Seq. ID No. 196, Seq. ID No. 202, Seq. ID No. 206, Seq. ID No. 208, Seq. ID No. 216, Seq. ID No. 220, Seq. ID No. 222, Seq. ID No. 224, Seq. ID No. 226, Seq. ID No. 228, Seq. ID No. 232, Seq. ID No. 234, Seq. ID No. 240, Seq. ID No. 244, Seq. ID No. 246, Seq. ID No. 248, Seq. ID No. 254, Seq. ID No. 258, Seq. ID No. 260, Seq. ID No. 262, Seq. ID No. 264, Seq. ID No. 266, Seq. ID No. 268, Seq. ID No. 270, Seq. ID No. 274, Seq. ID No. 278, Seq. ID No. 280, Seq. ID No. 282, Seq. ID No. 284, Seq. ID No. 292, Seq. ID No. 294, Seq. ID No. 298, Seq. ID No. 302, Seq. ID No. 306, Seq. ID No. 308, Seq. ID No. 310, Seq. ID No. 314, Seq. ID No. 318, Seq. ID No. 322, Seq. ID No. 324, Seq. ID No. 326, Seq. ID No. 332, Seq. ID No. 334, Seq. ID No. 336, Seq. ID No. 338, Seq. ID No. 340, Seq. ID No. 344, Seq. ID No. 346, Seq. ID No. 348, Seq. ID No. 350, Seq. ID No. 354, Seq. ID No. 356, Seq. ID No. 358, Seq. ID No. 360, Seq. ID No. 362, Seq. ID No. 364, Seq. ID No. 366, Seq. ID No. 368, Seq. ID No. 370, Seq. ID No. 372, Seq. ID No. 376, Seq. ID No. 378, Seq. ID No. 380, Seq. ID No. 384, Seq. ID No. 386, Seq. ID No. 388, Seq. ID No. 390, Seq. ID No. 392, Seq. ID No. 394, Seq. ID No. 398, Seq. ID No. 402, Seq. ID No. 404, Seq. ID No. 406, Seq. ID No. 408, Seq. ID No. 410, Seq. ID No. 416, Seq. ID No. 424, Seq. ID No. 426, Seq. ID No. 428, Seq. ID No. 430, Seq. ID No. 432, Seq. ID No. 434, Seq. ID No. 436, Seq. ID No. 438, Seq. ID No. 440, Seq. ID No. 442, Seq. ID No. 444, Seq. ID No. 446, Seq. ID No. 448, Seq. ID No. 452, Seq. ID No. 454, Seq. ID No. 456, Seq. ID No. 458, Seq. ID No. 462, Seq. ID No. 464, Seq. ID No. 468, Seq. ID No. 470, Seq. ID No. 472, Seq. ID No. 474, Seq. ID No. 476, Seq. ID No. 478, Seq. ID No. 480, Seq. ID No. 482, Seq. ID No. 484, Seq. ID No. 486, Seq. ID No. 490, Seq. ID No. 492, Seq. ID No. 494, Seq. ID No. 496, Seq. ID No. 502, Seq. ID No. 506, Seq. ID No. 508, Seq. ID No. 512, Seq. ID No. 516, Seq. ID No. 518, Seq. ID No. 524, Seq. ID No. 530, Seq. ID No. 532, Seq. ID No. 534, Seq. ID No. 538, Seq. ID No. 540, Seq. ID No. 544, Seq. ID No. 548, Seq. ID No. 550, Seq. ID No. 552, Seq. ID No. 554, Seq. ID No. 556, Seq. ID No. 558, Seq. ID No. 560, Seq. ID No. 562, Seq. ID No. 566, Seq. ID No. 570, Seq. ID No. 572, Seq. ID No. 574, Seq. ID No. 576, Seq. ID No. 580, Seq. ID No. 582, Seq. ID No. 586, Seq. ID No. 588, Seq. ID No. 590, Seq. ID No. 592, Seq. ID No. 594, Seq. ID No. 596, Seq. ID No. 598, Seq. ID No. 600, Seq. ID No. 602, Seq. ID No. 604, Seq. ID No. 606, Seq. ID No. 610, Seq. ID No. 614, Seq. ID No. 616, Seq. ID No. 618, Seq. ID No. 620, Seq. ID No. 622, Seq. ID No. 624, Seq. ID No. 626, Seq. ID No. 628, Seq. ID No. 636, Seq. ID No. 638, Seq. ID No. 644, Seq. ID No. 646, Seq. ID No. 648, Seq. ID No. 650, Seq. ID No. 656, Seq. ID No. 664, Seq. ID No. 666, Seq. ID No. 668, Seq. ID No. 670, Seq. ID No. 676, Seq. ID No. 682, Seq. ID No. 684, Seq. ID No. 688, Seq. ID No. 690, Seq. ID No. 692, Seq. ID No. 696, Seq. ID No. 698, Seq. ID No. 700, Seq. ID No. 702, Seq. ID No. 704, Seq. ID No. 706, Seq. ID No. 708, Seq. ID No. 710, Seq. ID No. 714, Seq. ID No. 726, Seq. ID No. 728, Seq. ID No. 730, Seq. ID No. 732, Seq. ID No. 734, Seq. ID No. 736, Seq. ID No. 740, Seq. ID No. 742, Seq. ID No. 746, Seq. ID No. 748, Seq. ID No. 750, Seq. ID No. 752, Seq. ID No. 754, Seq. ID No. 760, Seq. ID No. 764, Seq. ID No. 766, Seq. ID No. 774, Seq. ID No. 776, Seq. ID No. 782, Seq. ID No. 784, Seq. ID No. 788, Seq. ID No. 794, Seq. ID No. 796, Seq. ID No. 800, Seq. ID No. 802, Seq. ID No. 806, Seq. ID No. 808, Seq. ID No. 810, Seq. ID No. 812, Seq. ID No. 814, Seq. ID No. 816, Seq. ID No. 818, Seq. ID No. 820, Seq. ID No. 822, Seq. ID No. 824, Seq. ID No. 828, Seq. ID No. 830, Seq. ID No. 832, Seq. ID No. 836, Seq. ID No. 838, Seq. ID No. 840, Seq. ID No. 844, Seq. ID No. 846, Seq. ID No. 848, Seq. ID No. 856, Seq. ID No. 860, Seq. ID No. 862, Seq. ID No. 866, Seq. ID No. 868, Seq. ID No. 872, Seq. ID No. 874, Seq. ID No. 876, Seq. ID No. 878, Seq. ID No. 880, Seq. ID No. 882, Seq. ID No. 886, Seq. ID No. 896, Seq. ID No. 898, Seq. ID No. 900, Seq. ID No. 902, Seq. ID No. 904, Seq. ID No. 906, Seq. ID No. 908, Seq. ID No. 910, Seq. ID No. 914, Seq. ID No. 916, Seq. ID No. 922, Seq. ID No. 924, Seq. ID No. 926, Seq. ID No. 932, Seq. ID No. 934, Seq. ID No. 936, Seq. ID No. 938, Seq. ID No. 940, Seq. ID No. 942, Seq. ID No. 944, Seq. ID No. 948, Seq. ID No. 950, Seq. ID No. 952, Seq. ID No. 954, Seq. ID No. 956, Seq. ID No. 958, Seq. ID No. 962, Seq. ID No. 964, Seq. ID No. 966, Seq. ID No. 968, Seq. ID No. 970, Seq. ID No. 972, Seq. ID No. 974, Seq. ID No. 976, Seq. ID No. 982, Seq. ID No. 984, Seq. ID No. 986, Seq. ID No. 988, Seq. ID No. 990, Seq. ID No. 992, Seq. ID No. 994, Seq. ID No. 996, Seq. ID No. 998, Seq. ID No. 1002, Seq. ID No. 1004, Seq. ID No. 1006, Seq. ID No. 1008, Seq. ID No. 1010, Seq. ID No. 1018, Seq. ID No. 1020, Seq. ID No. 1024, Seq. ID No. 1026, Seq. ID No. 1028, Seq. ID No. 1040, Seq. ID No. 1042, Seq. ID No. 1044, Seq. ID No. 1046, Seq. ID No. 1048, Seq. ID No. 1050, Seq. ID No. 1052, Seq. ID No. 1058, Seq. ID No. 1060, Seq. ID No. 1062, Seq. ID No. 1066, Seq. ID No. 1070, Seq. ID No. 1076, Seq. ID No. 1078, Seq. ID No. 1080, Seq. ID No. 1082, Seq. ID No. 1084, Seq. ID No. 1086, Seq. ID No. 1088, Seq. ID No. 1092, Seq. ID No. 1094, Seq. ID No. 1096, Seq. ID No. 1098, Seq. ID No. 1100, Seq. ID No. 1102, Seq. ID No. 1104, Seq. ID No. 1108, Seq. ID No. 1110, Seq. ID No. 1112, Seq. ID No. 1114, Seq. ID No. 1116, Seq. ID No. 1120, Seq. ID No. 1122, Seq. ID No. 1124, Seq. ID No. 1126, Seq. ID No. 1128, Seq. ID No. 1130, Seq. ID No. 1132, Seq. ID No. 1138, Seq. ID No. 1140, Seq. ID No. 1142, Seq. ID No. 1144, Seq. ID No. 1146, Seq. ID No. 1148, Seq. ID No. 1150, Seq. ID No. 1152, Seq. ID No. 1154, Seq. ID No. 1156, Seq. ID No. 1158, Seq. ID No. 1160, Seq. ID No. 1162, Seq. ID No. 1164, Seq. ID No. 1172, Seq. ID No. 1176, Seq. ID No. 1178, Seq. ID No. 1180, Seq. ID No. 1182, Seq. ID No. 1188, Seq. ID No. 1192, Seq. ID No. 1194, Seq. ID No. 1196, Seq. ID No. 1198, Seq. ID No. 1202, Seq. ID No. 1204, Seq. ID No. 1206, Seq. ID No. 1208, Seq. ID No. 1212, Seq. ID No. 1214, Seq. ID No. 1216, Seq. ID No. 1218, Seq. ID No. 1222, Seq. ID No. 1224, Seq. ID No. 1226, Seq. ID No. 1232, Seq. ID No. 1234, Seq. ID No. 1238, Seq. ID No. 1240, Seq. ID No. 1242, Seq. ID No. 1246, Seq. ID No. 1248, Seq. ID No. 1250, Seq. ID No. 1252, Seq. ID No. 1254, Seq. ID No. 1256, Seq. ID No. 1258, Seq. ID No. 1260, Seq. ID No. 1262, Seq. ID No. 1264, Seq. ID No. 1272, Seq. ID No. 1274, Seq. ID No. 1276, Seq. ID No. 1278, Seq. ID No. 1280, Seq. ID No. 1286, Seq. ID No. 1290, Seq. ID No. 1292, Seq. ID No. 1294, Seq. ID No. 1296, Seq. ID No. 1298, Seq. ID No. 1300, Seq. ID No. 1302, Seq. ID No. 1304, Seq. ID No. 1306, Seq. ID No. 1308, Seq. ID No. 1310, Seq. ID No. 1312, Seq. ID No. 1314, Seq. ID No. 1318, Seq. ID No. 1320, Seq. ID No. 1322, Seq. ID No. 1332, Seq. ID No. 1334, Seq. ID No. 1336, Seq. ID No. 1338, Seq. ID No. 1340, Seq. ID No. 1344, Seq. ID No. 1346, Seq. ID No. 1348, Seq. ID No. 1350, Seq. ID No. 1352, Seq. ID No. 1360, Seq. ID No. 1362, Seq. ID No. 1364, Seq. ID No. 1366, Seq. ID No. 1370, Seq. ID No. 1372, Seq. ID No. 1376, Seq. ID No. 1378, Seq. ID No. 1382, Seq. ID No. 1384, Seq. ID No. 1386, Seq. ID No. 1388, Seq. ID No. 1390, Seq. ID No. 1392, Seq. ID No. 1394, Seq. ID No. 1402, Seq. ID No. 1404, Seq. ID No. 1408, Seq. ID No. 1410, Seq. ID No. 1412, Seq. ID No. 1414, Seq. ID No. 1416, Seq. ID No. 1420, Seq. ID No. 1422, Seq. ID No. 1424, Seq. ID No. 1426, Seq. ID No. 1428, Seq. ID No. 1430, Seq. ID No. 1434, Seq. ID No. 1438, Seq. ID No. 1442, Seq. ID No. 1444, Seq. ID No. 1448, Seq. ID No. 1450, Seq. ID No. 1452, Seq. ID No. 1456, Seq. ID No. 1460, Seq. ID No. 1464, Seq. ID No. 1466, Seq. ID No. 1468, Seq. ID No. 1470, Seq. ID No. 1472, Seq. ID No. 1474, Seq. ID No. 1476, Seq. ID No. 1478, Seq. ID No. 1480, Seq. ID No. 1484, Seq. ID No. 1486, Seq. ID No. 1488, Seq. ID No. 1492, Seq. ID No. 1494, Seq. ID No. 1496, Seq. ID No. 1498, Seq. ID No. 1500, Seq. ID No. 1502, Seq. ID No. 1506, Seq. ID No. 1508, Seq. ID No. 1512, Seq. ID No. 1518, Seq. ID No. 1520, Seq. ID No. 1524, Seq. ID No. 1526, Seq. ID No. 1528, Seq. ID No. 1532, Seq. ID No. 1540, Seq. ID No. 1544, Seq. ID No. 1550, Seq. ID No. 1552, Seq. ID No. 1554, Seq. ID No. 1556, Seq. ID No. 1558, Seq. ID No. 1562, Seq. ID No. 1564, Seq. ID No. 1566, Seq. ID No. 1568, Seq. ID No. 1572, Seq. ID No. 1574, Seq. ID No. 1576, Seq. ID No. 1578, Seq. ID No. 1580, Seq. ID No. 1582, Seq. ID No. 1590, Seq. ID No. 1594, Seq. ID No. 1596, Seq. ID No. 1598, Seq. ID No. 1600, Seq. ID No. 1602, Seq. ID No. 1608, Seq. ID No. 1612, Seq. ID No. 1614, Seq. ID No. 1616, Seq. ID No. 1618, Seq. ID No. 1620, Seq. ID No. 1624, Seq. ID No. 1626, Seq. ID No. 1628, Seq. ID No. 1634, Seq. ID No. 1638, Seq. ID No. 1640, Seq. ID No. 1642, Seq. ID No. 1644, Seq. ID No. 1648, Seq. ID No. 1652, Seq. ID No. 1654, Seq. ID No. 1656, Seq. ID No. 1658, Seq. ID No. 1662, Seq. ID No. 1664, Seq. ID No. 1666, Seq. ID No. 1670, Seq. ID No. 1676, Seq. ID No. 1680, Seq. ID No. 1682, Seq. ID No. 1686, Seq. ID No. 1688, Seq. ID No. 1690, Seq. ID No. 1692, Seq. ID No. 1694, Seq. ID No. 1696, Seq. ID No. 1698, Seq. ID No. 1700, Seq. ID No. 1704, Seq. ID No. 1706, Seq. ID No. 1708, Seq. ID No. 1712, Seq. ID No. 1714, Seq. ID No. 1716, Seq. ID No. 1718, Seq. ID No. 1720, Seq. ID No. 1722, Seq. ID No. 1724, Seq. ID No. 1728, Seq. ID No. 1730, Seq. ID No. 1736, Seq. ID No. 1738, Seq. ID No. 1740, Seq. ID No. 1742, Seq. ID No. 1748, Seq. ID No. 1750, Seq. ID No. 1752, Seq. ID No. 1756, Seq. ID No. 1758, Seq. ID No. 1760, Seq. ID No. 1764, Seq. ID No. 1770, Seq. ID No. 1772, Seq. ID No. 1776, Seq. ID No. 1778, Seq. ID No. 1780, Seq. ID No. 1782, Seq. ID No. 1784, Seq. ID No. 1786, Seq. ID No. 1790, Seq. ID No. 1792, Seq. ID No. 1794, Seq. ID No. 1796, Seq. ID No. 1798, Seq. ID No. 1806, Seq. ID No. 1810, Seq. ID No. 1812, Seq. ID No. 1814, Seq. ID No. 1816, Seq. ID No. 1818, Seq. ID No. 1820, Seq. ID No. 1822, Seq. ID No. 1824, Seq. ID No. 1826, Seq. ID No. 1830, Seq. ID No. 1834, Seq. ID No. 1842, Seq. ID No. 1844, Seq. ID No. 1846, Seq. ID No. 1848, Seq. ID No. 1850, Seq. ID No. 1854, Seq. ID No. 1856, Seq. ID No. 1858, Seq. ID No. 1860, Seq. ID No. 1862, Seq. ID No. 1864, Seq. ID No. 1866, Seq. ID No. 1868, Seq. ID No. 1872, Seq. ID No. 1874, Seq. ID No. 1876, Seq. ID No. 1878, Seq. ID No. 1882, Seq. ID No. 1884, Seq. ID No. 1886, Seq. ID No. 1888, Seq. ID No. 1890, Seq. ID No. 1896, Seq. ID No. 1904, Seq. ID No. 1906, Seq. ID No. 1908, Seq. ID No. 1912, Seq. ID No. 1914, Seq. ID No. 1916, Seq. ID No. 1920, Seq. ID No. 1924, Seq. ID No. 1926, Seq. ID No. 1928, Seq. ID No. 1930, Seq. ID No. 1932, Seq. ID No. 1936, Seq. ID No. 1942, Seq. ID No. 1944, Seq. ID No. 1946, Seq. ID No. 1948, Seq. ID No. 1950, Seq. ID No. 1952, Seq. ID No. 1954, Seq. ID No. 1960, Seq. ID No. 1962, Seq. ID No. 1964, Seq. ID No. 1966, Seq. ID No. 1968, Seq. ID No. 1970, Seq. ID No. 1972, Seq. ID No. 1980, Seq. ID No. 1984, Seq. ID No. 1986, Seq. ID No. 1988, Seq. ID No. 1990, Seq. ID No. 1992, Seq. ID No. 1996, Seq. ID No. 1998, Seq. ID No. 2000, Seq. ID No. 2002, Seq. ID No. 2004, Seq. ID No. 2006, Seq. ID No. 2008, Seq. ID No. 2016, Seq. ID No. 2020, Seq. ID No. 2022, Seq. ID No. 2026, Seq. ID No. 2028, Seq. ID No. 2030, Seq. ID No. 2032, Seq. ID No. 2036, Seq. ID No. 2038, Seq. ID No. 2042, Seq. ID No. 2044, Seq. ID No. 2046, Seq. ID No. 2048, Seq. ID No. 2054, Seq. ID No. 2056, Seq. ID No. 2060, Seq. ID No. 2064, Seq. ID No. 2066, Seq. ID No. 2068, Seq. ID No. 2070, Seq. ID No. 2072, Seq. ID No. 2074, Seq. ID No. 2076, Seq. ID No. 2078, Seq. ID No. 2080, Seq. ID No. 2082, Seq. ID No. 2084, Seq. ID No. 2086, Seq. ID No. 2090, Seq. ID No. 2092, Seq. ID No. 2094, Seq. ID No. 2098, Seq. ID No. 2100, Seq. ID No. 2102, Seq. ID No. 2104, Seq. ID No. 2108, Seq. ID No. 2110, Seq. ID No. 2112, Seq. ID No. 2116, Seq. ID No. 2118, Seq. ID No. 2120, Seq. ID No. 2126, Seq. ID No. 2128, Seq. ID No. 2130, Seq. ID No. 2132, Seq. ID No. 2134, Seq. ID No. 2136, Seq. ID No. 2138, Seq. ID No. 2142, Seq. ID No. 2144, Seq. ID No. 2146, Seq. ID No. 2150, Seq. ID No. 2152, Seq. ID No. 2154, Seq. ID No. 2156, Seq. ID No. 2158, Seq. ID No. 2160, Seq. ID No. 2162, Seq. ID No. 2166, Seq. ID No. 2168, Seq. ID No. 2170, Seq. ID No. 2180, Seq. ID No. 2182, Seq. ID No. 2184, Seq. ID No. 2190, Seq. ID No. 2192, Seq. ID No. 2196, Seq. ID No. 2198, Seq. ID No. 2200, Seq. ID No. 2202, Seq. ID No. 2204, Seq. ID No. 2206, Seq. ID No. 2208, Seq. ID No. 2210, Seq. ID No. 2212, Seq. ID No. 2214, Seq. ID No. 2216, Seq. ID No. 2218, Seq. ID No. 2222, Seq. ID No. 2224, Seq. ID No. 2228, Seq. ID No. 2230, Seq. ID No. 2236, Seq. ID No. 2242, Seq. ID No. 2246, Seq. ID No. 2248, Seq. ID No. 2252, Seq. ID No. 2254, Seq. ID No. 2258, Seq. ID No. 2260, Seq. ID No. 2262, Seq. ID No. 2264, Seq. ID No. 2266, Seq. ID No. 2268, Seq. ID No. 2270, Seq. ID No. 2276, Seq. ID No. 2278, Seq. ID No. 2280, Seq. ID No. 2286, Seq. ID No. 2288, Seq. ID No. 2298, Seq. ID No. 2300, Seq. ID No. 2302, Seq. ID No. 2310, Seq. ID No. 2312, Seq. ID No. 2316, Seq. ID No. 2328, Seq. ID No. 2330, Seq. ID No. 2334, Seq. ID No. 2344, Seq. ID No. 2346, Seq. ID No. 2350, Seq. ID No. 2352, Seq. ID No. 2358, Seq. ID No. 2364, Seq. ID No. 2366, Seq. ID No. 2368, Seq. ID No. 2370, Seq. ID No. 2372, Seq. ID No. 2374, Seq. ID No. 2376, Seq. ID No. 2380, Seq. ID No. 2382, Seq. ID No. 2386, Seq. ID No. 2388, Seq. ID No. 2392, Seq. ID No. 2394, Seq. ID No. 2396, Seq. ID No. 2398, Seq. ID No. 2400, Seq. ID No. 2402, Seq. ID No. 2406, Seq. ID No. 2410, Seq. ID No. 2414, Seq. ID No. 2416, Seq. ID No. 2418, Seq. ID No. 2422, Seq. ID No. 2424, Seq. ID No. 2426, Seq. ID No. 2428, Seq. ID No. 2430, Seq. ID No. 2436, Seq. ID No. 2438, Seq. ID No. 2446, Seq. ID No. 2448, Seq. ID No. 2450, Seq. ID No. 2452, Seq. ID No. 2454, Seq. ID No. 2456, Seq. ID No. 2458, Seq. ID No. 2460, Seq. ID No. 2462, Seq. ID No. 2464, Seq. ID No. 2466, Seq. ID No. 2470, Seq. ID No. 2472, Seq. ID No. 2476, Seq. ID No. 2482, Seq. ID No. 2484, Seq. ID No. 2486, Seq. ID No. 2492, Seq. ID No. 2494, Seq. ID No. 2496, Seq. ID No. 2500, Seq. ID No. 2502, Seq. ID No. 2504, Seq. ID No. 2506, Seq. ID No. 2508, Seq. ID No. 2512, Seq. ID No. 2514, Seq. ID No. 2518, Seq. ID No. 2520, Seq. ID No. 2522, Seq. ID No. 2526, Seq. ID No. 2530, Seq. ID No. 2534, Seq. ID No. 2536, Seq. ID No. 2538, Seq. ID No. 2540, Seq. ID No. 2548, Seq. ID No. 2550, Seq. ID No. 2552, Seq. ID No. 2554, Seq. ID No. 2560, Seq. ID No. 2562, Seq. ID No. 2564, Seq. ID No. 2566, Seq. ID No. 2574, Seq. ID No. 2576, Seq. ID No. 2578, Seq. ID No. 2580, Seq. ID No. 2582, Seq. ID No. 2588, Seq. ID No. 2590, Seq. ID No. 2592, Seq. ID No. 2594, Seq. ID No. 2596, Seq. ID No. 2600, Seq. ID No. 2604, Seq. ID No. 2606, Seq. ID No. 2608, Seq; ID No. 2610, Seq. ID No. 2612, Seq. ID No. 2614, Seq. ID No. 2618, Seq. ID No. 2620, Seq. ID No. 2624, Seq. ID No. 2626, Seq. ID No. 2628, Seq. ID No. 2630, Seq. ID No. 2632, Seq. ID No. 2634, Seq. ID No. 2636, Seq. ID No. 2638, Seq. ID No. 2640, Seq. ID No. 2642, Seq. ID No. 2644, Seq. ID No. 2646, Seq. ID No. 2648, Seq. ID No. 2650, Seq. ID No. 2652, Seq. ID No. 2654, Seq. ID No. 2656, Seq. ID No. 2660, Seq. ID No. 2664, Seq. ID No. 2668, Seq. ID No. 2670, Seq. ID No. 2672, Seq. ID No. 2676, Seq. ID No. 2678, Seq. ID No. 2684, Seq. ID No. 2686, Seq. ID No. 2688, Seq. ID No. 2690, Seq. ID No. 2692, Seq. ID No. 2694, Seq. ID No. 2696, Seq. ID No. 2698, Seq. ID No. 2700, Seq. ID No. 2704, Seq. ID No. 2710, Seq. ID No. 2712, Seq. ID No. 2716, Seq. ID No. 2718, Seq. ID No. 2720, Seq. ID No. 2724, Seq. ID No. 2726, Seq. ID No. 2728, Seq. ID No. 2730, Seq. ID No. 2732, Seq. ID No. 2736, Seq. ID No. 2738, Seq. ID No. 2740, Seq. ID No. 2750, Seq. ID No. 2752, Seq. ID No. 2754, Seq. ID No. 2756, Seq. ID No. 2760, Seq. ID No. 2766, Seq. ID No. 2768, Seq. ID No. 2770, Seq. ID No. 2772, Seq. ID No. 2774, Seq. ID No. 2776, Seq. ID No. 2780, Seq. ID No. 2782, Seq. ID No. 2784, Seq. ID No. 2788, Seq. ID No. 2790, Seq. ID No. 2792, Seq. ID No. 2794, Seq. ID No. 2796, Seq. ID No. 2798, Seq. ID No. 2800, Seq. ID No. 2802, Seq. ID No. 2804, Seq. ID No. 2808, Seq. ID No. 2810, Seq. ID No. 2814, Seq. ID No. 2816, Seq. ID No. 2822, Seq. ID No. 2824, Seq. ID No. 2828, Seq. ID No. 2830, Seq. ID No. 2832, Seq. ID No. 2834, Seq. ID No. 2840, Seq. ID No. 2842, Seq. ID No. 2844, Seq. ID No. 2846, Seq. ID No. 2848, Seq. ID No. 2856, Seq. ID No. 2862, Seq. ID No. 2864, Seq. ID No. 2866, Seq. ID No. 2868, Seq. ID No. 2870, Seq. ID No. 2872, Seq. ID No. 2878, Seq. ID No. 2882, Seq. ID No. 2884, Seq. ID No. 2886, Seq. ID No. 2888, Seq. ID No. 2892, Seq. ID No. 2894, Seq. ID No. 2896, Seq. ID No. 2900, Seq. ID No. 2902, Seq. ID No. 2908, Seq. ID No. 2916, Seq. ID No. 2918, Seq. ID No. 2920, Seq. ID No. 2922, Seq. ID No. 2924, Seq. ID No. 2928, Seq. ID No. 2932, Seq. ID No. 2934, Seq. ID No. 2936, Seq. ID No. 2944, Seq. ID No. 2946, Seq. ID No. 2952, Seq. ID No. 2954, Seq. ID No. 2958, Seq. ID No. 2960, Seq. ID No. 2962, Seq. ID No. 2964, Seq. ID No. 2966, Seq. ID No. 2968, Seq. ID No. 2972, Seq. ID No. 2974, Seq. ID No. 2976, Seq. ID No. 2978, Seq. ID No. 2980, Seq. ID No. 2984, Seq. ID No. 2986, Seq. ID No. 2988, Seq. ID No. 2992, Seq. ID No. 2994, Seq. ID No. 3000, Seq. ID No. 3002, Seq. ID No. 3006, Seq. ID No. 3010, Seq. ID No. 3012, Seq. ID No. 3016, Seq. ID No. 3018, Seq. ID No. 3020, Seq. ID No. 3022, Seq. ID No. 3028, Seq. ID No. 3034, Seq. ID No. 3036, Seq. ID No. 3038, Seq. ID No. 3040, Seq. ID No. 3044, Seq. ID No. 3046, Seq. ID No. 3048, Seq. ID No. 3050, Seq. ID No. 3052, Seq. ID No. 3054, Seq. ID No. 3056, Seq. ID No. 3058, Seq. ID No. 3060, Seq. ID No. 3068, Seq. ID No. 3070, Seq. ID No. 3072, Seq. ID No. 3080, Seq. ID No. 3084, Seq. ID No. 3086, Seq. ID No. 3088, Seq. ID No. 3092, Seq. ID No. 3094, Seq. ID No. 3100, Seq. ID No. 3102, Seq. ID No. 3104, Seq. ID No. 3110, Seq. ID No. 3112, Seq. ID No. 3116, Seq. ID No. 3118, Seq. ID No. 3120, Seq. ID No. 3122, Seq. ID No. 3124, Seq. ID No. 3126, Seq. ID No. 3130, Seq. ID No. 3132, Seq. ID No. 3134, Seq. ID No. 3136, Seq. ID No. 3138, Seq. ID No. 3140, Seq. ID No. 3142, Seq. ID No. 3144, Seq. ID No. 3148, Seq. ID No. 3150, Seq. ID No. 3152, Seq. ID No. 3154, Seq. ID No. 3156, Seq. ID No. 3158, Seq. ID No. 3160, Seq. ID No. 3162, Seq. ID No. 3166, Seq. ID No. 3168, Seq. ID No. 3170, Seq. ID No. 3172, Seq. ID No. 3174, Seq. ID No. 3180, Seq. ID No. 3182, Seq. ID No. 3184, Seq. ID No. 3186, Seq. ID No. 3188, Seq. ID No. 3190, Seq. ID No. 3192, Seq. ID No. 3194, Seq. ID No. 3196, Seq. ID No. 3198, Seq. ID No. 3204, Seq. ID No. 3206, Seq. ID No. 3208, Seq. ID No. 3210, Seq. ID No. 3212, Seq. ID No. 3218, Seq. ID No. 3224, Seq. ID No. 3226, Seq. ID No. 3228, Seq. ID No. 3230, Seq. ID No. 3236, Seq. ID No. 3250, Seq. ID No. 3252, Seq. ID No. 3254, Seq. ID No. 3256, Seq. ID No. 3258, Seq. ID No. 3260, Seq. ID No. 3264, Seq. ID No. 3266, Seq. ID No. 3270, Seq. ID No. 3272, Seq. ID No. 3274, Seq. ID No. 3278, Seq. ID No. 3282, Seq. ID No. 3284, Seq. ID No. 3286, Seq. ID No. 3290, Seq. ID No. 3292, Seq. ID No. 3294, Seq. ID No. 3300, Seq. ID No. 3302, Seq. ID No. 3304, Seq. ID No. 3306, Seq. ID No. 3308, Seq. ID No. 3310, Seq. ID No. 3312, Seq. ID No. 3314, Seq. ID No. 3316, Seq. ID No. 3320, Seq. ID No. 3322, Seq. ID No. 3324, Seq. ID No. 3326, Seq. ID No. 3332, Seq. ID No. 3336, Seq. ID No. 3338, Seq. ID No. 3340, Seq. ID No. 3342, Seq. ID No. 3346, Seq. ID No. 3348, Seq. ID No. 3350, Seq. ID No. 3354, Seq. ID No. 3356, Seq. ID No. 3360, Seq. ID No. 3362, Seq. ID No. 3364, Seq. ID No. 3366, Seq. ID No. 3368, Seq. ID No. 3370, Seq. ID No. 3372, Seq. ID No. 3374, Seq. ID No. 3376, Seq. ID No. 3378, Seq. ID No. 3380, Seq. ID No. 3382, Seq. ID No. 3384, Seq. ID No. 3398, Seq. ID No. 3400, Seq. ID No. 3402, Seq. ID No. 3408, Seq. ID No. 3410, Seq. ID No. 3414, Seq. ID No. 3416, Seq. ID No. 3420, Seq. ID No. 3426, Seq. ID No. 3428, Seq. ID No. 3432, Seq. ID No. 3434, Seq. ID No. 3436, Seq. ID No. 3440, Seq. ID No. 3442, Seq. ID No. 3444, Seq. ID No. 3446, Seq. ID No. 3448, Seq. ID No. 3456, Seq. 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ID No. 5278, Seq. ID No. 5280, Seq. ID No. 5282, Seq. ID No. 5286, Seq. ID No. 5288, Seq. ID No. 5292, Seq. ID No. 5296, Seq. ID No. 5298, Seq. ID No. 5300, Seq. ID No. 5302, Seq. ID No. 5304, Seq. ID No. 5306, Seq. ID No. 5308, Seq. ID No. 5310, Seq. ID No. 5312, Seq. ID No. 5314, Seq. ID No. 5318, Seq. ID No. 5320, Seq. ID No. 5322, Seq. ID No. 5324, Seq. ID No. 5328, Seq. ID No. 5330, Seq. ID No. 5332, Seq. ID No. 5334, Seq. ID No. 5336, Seq. ID No. 5338, Seq. ID No. 5344, Seq. ID No. 5346, Seq. ID No. 5350, Seq. ID No. 5352, Seq. ID No. 5358, Seq. ID No. 5360, Seq. ID No. 5366, Seq. ID No. 5368, Seq. ID No. 5374, Seq. ID No. 5378, Seq. ID No. 5380, Seq. ID No. 5382, Seq. ID No. 5384, Seq. ID No. 5388, Seq. ID No. 5390, Seq. ID No. 5392, Seq. ID No. 5394, Seq. ID No. 5398, Seq. ID No. 5400, Seq. ID No. 5402, Seq. ID No. 5404, Seq. ID No. 5406, Seq. ID No. 5408, Seq. ID No. 5410, Seq. ID No. 5412, Seq. ID No. 5416, Seq. ID No. 5418, Seq. ID No. 5420, Seq. ID No. 5422, Seq. ID No. 5424, Seq. ID No. 5426, Seq. ID No. 5428, Seq. ID No. 5432, Seq. ID No. 5434, Seq. ID No. 5436, Seq. ID No. 5438, Seq. ID No. 5440, Seq. ID No. 5442, Seq. ID No. 5444, Seq. ID No. 5448, Seq. ID No. 5450, Seq. ID No. 5452, Seq. ID No. 5454, Seq. ID No. 5456, Seq. ID No. 5458, Seq. ID No. 5468, Seq. ID No. 5472, Seq. ID No. 5474, Seq. ID No. 5478, Seq. ID No. 5480, Seq. ID No. 5482, Seq. ID No. 5492, Seq. ID No. 5494, Seq. ID No. 5496, Seq. ID No. 5500, Seq. ID No. 5504, Seq. ID No. 5510, Seq. ID No. 5514, Seq. ID No. 5516, Seq. ID No. 5518, Seq. ID No. 5520, Seq. ID No. 5522, Seq. ID No. 5528, Seq. ID No. 5530, Seq. ID No. 5532, Seq. ID No. 5534, Seq. ID No. 5538, Seq. ID No. 5540, Seq. ID No. 5542, Seq. ID No. 5544, Seq. ID No. 5546, Seq. ID No. 5548, Seq. ID No. 5550, Seq. ID No. 5552, Seq. ID No. 5554, Seq. ID No. 5558, Seq. ID No. 5560, Seq. ID No. 5564, Seq. ID No. 5568, Seq. ID No. 5570, Seq. ID No. 5576, Seq. ID No. 5578, Seq. ID No. 5582, Seq. ID No. 5584, Seq. ID No. 5586, Seq. ID No. 5590, Seq. ID No. 5592, Seq. ID No. 5594, Seq. ID No. 5596, Seq. ID No. 5600, Seq. ID No. 5602, Seq. ID No. 5608, Seq. ID No. 5614, Seq. ID No. 5616, Seq. ID No. 5618, Seq. ID No. 5620, Seq. ID No. 5622, Seq. ID No. 5626, Seq. ID No. 5628, Seq. ID No. 5630, Seq. ID No. 5632, Seq. ID No. 5638, Seq. ID No. 5640, Seq. ID No. 5642, Seq. ID No. 5646, Seq. ID No. 5648, Seq. ID No. 5650, Seq. ID No. 5652, Seq. ID No. 5656, Seq. ID No. 5658, Seq. ID No. 5662, Seq. ID No. 5666, Seq. ID No. 5668, Seq. ID No. 5670, Seq. ID No. 5678, Seq. ID No. 5680, Seq. ID No. 5684, Seq. ID No. 5686, Seq. ID No. 5688, Seq. ID No. 5690, Seq. ID No. 5692, Seq. ID No. 5694, Seq. ID No. 5698, Seq. ID No. 5700, Seq. ID No. 5702, Seq. ID No. 5704, Seq. ID No. 5706, Seq. ID No. 5708, Seq. ID No. 5712, Seq. ID No. 5714, Seq. ID No. 5716, Seq. ID No. 5718, Seq. ID No. 5720, Seq. ID No. 5722, Seq. ID No. 5724, Seq. ID No. 5726, Seq. ID No. 5728, Seq. ID No. 5736, Seq. ID No. 5740, Seq. ID No. 5742, Seq. ID No. 5744, Seq. ID No. 5746, Seq. ID No. 5748, Seq. ID No. 5750, Seq. ID No. 5752, Seq. ID No. 5754, Seq. ID No. 5756, Seq. ID No. 5758, Seq. ID No. 5760, Seq. ID No. 5762, Seq. ID No. 5770, Seq. ID No. 5772, Seq. ID No. 5778, Seq. ID No. 5780, Seq. ID No. 5784, Seq. ID No. 5788, Seq. ID No. 5792, Seq. ID No. 5796, Seq. ID No. 5800, Seq. ID No. 5802, Seq. ID No. 5808, Seq. ID No. 5810, Seq. ID No. 5814, Seq. ID No. 5816, Seq. ID No. 5820, Seq. ID No. 5822, Seq. ID No. 5824, Seq. ID No. 5826, Seq. ID No. 5828, Seq. ID No. 5830, Seq. ID No. 5832, Seq. ID No. 5834, Seq. ID No. 5836, Seq. ID No. 5838, Seq. ID No. 5840, Seq. ID No. 5842, Seq. ID No. 5846, Seq. ID No. 5848, Seq. ID No. 5850, Seq. ID No. 5852, Seq. ID No. 5856, Seq. ID No. 5858, Seq. ID No. 5860, Seq. ID No. 5862, Seq. ID No. 5864, Seq. ID No. 5866, Seq. ID No. 5870, Seq. ID No. 5872, Seq. ID No. 5874, Seq. ID No. 5876, Seq. ID No. 5880, Seq. ID No. 5882, Seq. ID No. 5884, Seq. ID No. 5890, Seq. ID No. 5896, Seq. ID No. 5898, Seq. ID No. 5902, Seq. ID No. 5904, Seq. ID No. 5912, Seq. ID No. 5914, Seq. ID No. 5916, Seq. ID No. 5918, Seq. ID No. 5920, Seq. ID No. 5928, Seq. ID No. 5930, Seq. ID No. 5934, Seq. ID No. 5936, Seq. ID No. 5938, Seq. ID No. 5942, Seq. ID No. 5946, Seq. ID No. 5948, Seq. ID No. 5952, Seq. ID No. 5960, Seq. ID No. 5962, Seq. ID No. 5964, Seq. ID No. 5966, Seq. ID No. 5968, Seq. ID No. 5970, Seq. ID No. 5972, Seq. ID No. 5974, Seq. ID No. 5978, Seq. ID No. 5980, Seq. ID No. 5982, Seq. ID No. 5986, Seq. ID No. 5988, Seq. ID No. 5990, Seq. ID No. 5992, Seq. ID No. 5994, Seq. ID No. 5996, Seq. ID No. 6000, Seq. ID No. 6002, Seq. ID No. 6004, Seq. ID No. 6010, Seq. ID No. 6012, Seq. ID No. 6014, Seq. ID No. 6016, Seq. ID No. 6018, Seq. ID No. 6026, Seq. ID No. 6028, Seq. ID No. 6030, Seq. ID No. 6032, Seq. ID No. 6034, Seq. ID No. 6036, Seq. ID No. 6040, Seq. ID No. 6042, Seq. ID No. 6044, Seq. ID No. 6046, Seq. ID No. 6050, Seq. ID No. 6052, Seq. ID No. 6054, Seq. ID No. 6056, Seq. ID No. 6058, Seq. ID No. 6062, Seq. ID No. 6064, Seq. ID No. 6066, Seq. ID No. 6070, Seq. ID No. 6072, Seq. ID No. 6074, Seq. ID No. 6078, Seq. ID No. 6080, Seq. ID No. 6086, Seq. ID No. 6088, Seq. ID No. 6090, Seq. ID No. 6094, Seq. ID No. 6096, Seq. ID No. 6102, Seq. ID No. 6104, Seq. ID No. 6110, Seq. ID No. 6112, Seq. ID No. 6118, Seq. ID No. 6122, Seq. ID No. 6124, Seq. ID No. 6130, Seq. ID No. 6132, Seq. ID No. 6134, Seq. ID No. 6136, Seq. ID No. 6138, Seq. ID No. 6140, Seq. ID No. 6142, Seq. ID No. 6146, Seq. ID No. 6152, Seq. ID No. 6156, Seq. ID No. 6158, Seq. ID No. 6160, Seq. ID No. 6166, Seq. ID No. 6168, Seq. ID No. 6170, Seq. ID No. 6172, Seq. ID No. 6176, Seq. ID No. 6178, Seq. ID No. 6182, Seq. ID No. 6188, Seq. ID No. 6194, Seq. ID No. 6196, Seq. ID No. 6198, Seq. ID No. 6200, Seq. ID No. 6202, Seq. ID No. 6210, Seq. ID No. 6214, Seq. ID No. 6216, Seq. ID No. 6218, Seq. ID No. 6220, Seq. ID No. 6232, Seq. ID No. 6234, Seq. ID No. 6236, Seq. ID No. 6240, Seq. ID No. 6242, Seq. ID No. 6244, Seq. ID No. 6250, Seq. ID No. 6258, Seq. ID No. 6260, Seq. ID No. 6262, Seq. ID No. 6264, Seq. ID No. 6268, Seq. ID No. 6270, Seq. ID No. 6272, Seq. ID No. 6276, Seq. ID No. 6278, Seq. ID No. 6280, Seq. ID No. 6282, Seq. ID No. 6284, Seq. ID No. 6286, Seq. ID No. 6288, Seq. ID No. 6294, Seq. ID No: 6296, Seq. ID No. 6298, Seq. ID No. 6300, Seq. ID No. 6306, Seq. ID No. 6310, Seq. ID No. 6312, Seq. ID No. 6316, Seq. ID No. 6318, Seq. ID No. 6320, Seq. ID No. 6322, Seq. ID No. 6324, Seq. ID No. 6326, Seq. ID No. 6328, Seq. ID No. 6330, Seq. ID No. 6332, Seq. ID No. 6336, Seq. ID No. 6338, Seq. ID No. 6342, Seq. ID No. 6346, Seq. ID No. 6350, Seq. ID No. 6352, Seq. ID No. 6354, Seq. ID No. 6360, Seq. ID No. 6362, Seq. ID No. 6368, Seq. ID No. 6370, Seq. ID No. 6372, Seq. ID No. 6374, Seq. ID No. 6376, Seq. ID No. 6378, Seq. ID No. 6380, Seq. ID No. 6382, Seq. ID No. 6386, Seq. ID No. 6390, Seq. ID No. 6394, Seq. ID No. 6396, Seq. ID No. 6400, Seq. ID No. 6410, Seq. ID No. 6412, Seq. ID No. 6414, Seq. ID No. 6418, Seq. ID No. 6422, Seq. ID No. 6424, Seq. ID No. 6426, Seq. ID No. 6428, Seq. ID No. 6430, Seq. ID No. 6432, Seq. ID No. 6442, Seq. ID No. 644.4, Seq. ID No. 6446, Seq. ID No. 6452, Seq. ID No. 6454, Seq. ID No. 6460, Seq. ID No. 6462, Seq. ID No. 6464, Seq. ID No. 6466, Seq. ID No. 6468, Seq. ID No. 6470, Seq. ID No. 6472, Seq. ID No. 6474, Seq. ID No. 6480, Seq. ID No. 6484, Seq. ID No. 6494, Seq. ID No. 6496, Seq. ID No. 6498, Seq. ID No. 6502, Seq. ID No. 6504, Seq. ID No. 6506, Seq. ID No. 6508, Seq. ID No. 6512, Seq. ID No. 6518, Seq. ID No. 6524, Seq. ID No. 6526, Seq. ID No. 6536, Seq. ID No. 6538, Seq. ID No. 6540, Seq. ID No. 6542, Seq. ID No. 6544, Seq. ID No. 6546, Seq. ID No. 6548, Seq. ID No. 6550, Seq. ID No. 6552, Seq. ID No. 6554, Seq. ID No. 6556, Seq. ID No. 6558, Seq. ID No. 6560, Seq. ID No. 6564, Seq. ID No. 6574, Seq. ID No. 6576, Seq. ID No. 6578, Seq. ID No. 6580, Seq. ID No. 6584, Seq. ID No. 6586, Seq. ID No. 6588, Seq. ID No. 6592, Seq. ID No. 6598, Seq. ID No. 6602, Seq. ID No. 6604, Seq. ID No. 6606, Seq. ID No. 6610, Seq. ID No. 6612, Seq. ID No. 6614, Seq. ID No. 6616, Seq. ID No. 6618, Seq. ID No. 6620, Seq. ID No. 6622, Seq. ID No. 6624, Seq. ID No. 6628, Seq. ID No. 6630, Seq. ID No. 6632, Seq. ID No. 6634, Seq. ID No. 6638, Seq. ID No. 6640, Seq. ID No. 6644, Seq. ID No. 6646, and Seq. ID No.
 6650. 55. The Alloiococcus otitidis polypeptide of claim 36, wherein the polypeptide is identified by an ORF finder program that searches for a transmembrane domain between two Stop codons and a Start codon immediately upstream of this transmembrane region, and is selected from one of Seq. ID No. 8, Seq. ID No. 10, Seq. ID No. 34, Seq. ID No. 48, Seq. ID No. 68, Seq. ID No. 86, Seq. ID No. 88, Seq. ID No. 124, Seq. ID No. 134, Seq. ID No. 142, Seq. ID No. 160, Seq. ID No. 164, Seq. ID No. 192, Seq. ID No. 210, Seq. ID No. 212, Seq. ID No. 216, Seq. ID No. 218, Seq. ID No. 226, Seq. ID No. 236, Seq. ID No. 238, Seq. ID No. 250, Seq. ID No. 252, Seq. ID No. 256, Seq. ID No. 272, Seq. ID No. 278, Seq. ID No. 286, Seq. ID No. 288, Seq. ID No. 290, Seq. ID No. 328, Seq. ID No. 330, Seq. ID No. 374, Seq. ID No. 376, Seq. ID No. 420, Seq. ID No. 488, Seq. ID No. 498, Seq. ID No. 500, Seq. ID No. 504, Seq. ID No. 506, Seq. ID No. 510, Seq. ID No. 512, Seq. ID No. 516, Seq. ID No. 526, Seq. ID No. 528, Seq. ID No. 546, Seq. ID No. 568, Seq. ID No. 570, Seq. ID No. 576, Seq. ID No. 578, Seq. ID No. 580, Seq. ID No. 594, Seq. ID No. 618, Seq. ID No. 638, Seq. ID No. 640, Seq. ID No. 642, Seq. ID No. 646, Seq. ID No. 654, Seq. ID No. 656, Seq. ID No. 660, Seq. ID No. 670, Seq. ID No. 676, Seq. ID No. 678, Seq. ID No. 680, Seq. ID No. 716, Seq. ID No. 718, Seq. ID No. 720, Seq. ID No. 722, Seq. ID No. 724, Seq. ID No. 748, Seq. ID No. 752, Seq. ID No. 756, Seq. ID No. 758, Seq. ID No. 760, Seq. ID No. 762, Seq. ID No. 764, Seq. ID No. 770, Seq. ID No. 778, Seq. ID No. 780, Seq. ID No. 808, Seq. ID No. 810, Seq. ID No. 820, Seq. ID No. 826, Seq. ID No. 864, Seq. ID No. 894, Seq. ID No. 902, Seq. ID No. 936, Seq. ID No. 944, Seq. ID No. 956, Seq. ID No. 968, Seq. ID No. 980, Seq. ID No. 1006, Seq. ID No. 1010, Seq. ID No. 1012, Seq. ID No. 1014, Seq. ID No. 1016, Seq. ID No. 1020, Seq. ID No. 1030, Seq. ID No. 1032, Seq. ID No. 1034, Seq. ID No. 1038, Seq. ID No. 1040, Seq. ID No. 1046, Seq. ID No. 1056, Seq. ID No. 1076, Seq. ID No. 1106, Seq. ID No. 1132, Seq. ID No. 1136, Seq. ID No. 1138, Seq. ID No. 1166, Seq. ID No. 1168, Seq. ID No. 1170, Seq. ID No. 1184, Seq. ID No. 1194, Seq. ID No. 1198, Seq. ID No. 1214, Seq. ID No. 1224, Seq. ID No. 1228, Seq. ID No. 1230, Seq. ID No. 1238, Seq. ID No. 1244, Seq. ID No. 1266, Seq. ID No. 1268, Seq. ID No. 1270, Seq. ID No. 1272, Seq. ID No. 1284, Seq. ID No. 1288, Seq. ID No. 1292, Seq. ID No. 1298, Seq. ID No. 1306, Seq. ID No. 1316, Seq. ID No. 1326, Seq. ID No. 1328, Seq. ID No. 1330, Seq. ID No. 1332, Seq. ID No. 1342, Seq. ID No. 1354, Seq. ID No. 1368, Seq. ID No. 1402, Seq. ID No. 1430, Seq. ID No. 1436, Seq. ID No. 1446, Seq. ID No. 1482, Seq. ID No. 1514, Seq. ID No. 1516, Seq. ID No. 1518, Seq. ID No. 1530, Seq. ID No. 1534, Seq. ID No. 1536, Seq. ID No. 1546, Seq. ID No. 1548, Seq. ID No. 1552, Seq. ID No. 1560, Seq. ID No. 1564, Seq. ID No. 1572, Seq. ID No. 1580, Seq. ID No. 1584, Seq. ID No. 1586, Seq. ID No. 1622, Seq. ID No. 1634, Seq. ID No. 1644, Seq. ID No. 1646, Seq. ID No. 1648, Seq. ID No. 1650, Seq. ID No. 1654, Seq. ID No. 1672, Seq. ID No. 1674, Seq. ID No. 1678, Seq. ID No. 1682, Seq. ID No. 1708, Seq. ID No. 1732, Seq. ID No. 1734, Seq. ID No. 1738; Seq. ID No. 1754, Seq: ID No. 1758, Seq. ID No. 1766, Seq. ID No. 1768, Seq. ID No. 1788, Seq. ID No. 1792, Seq. ID No. 1798, Seq. ID No. 1806, Seq. ID No. 1820, Seq. ID No. 1822, Seq. ID No. 1824, Seq. ID No. 1840, Seq. ID No. 1870, Seq. ID No. 1876, Seq. ID No. 1892, Seq. ID No. 1894, Seq. ID No. 1896, Seq. ID No. 1924, Seq. ID No. 1928, Seq. ID No. 1970, Seq. ID No. 1982, Seq. ID No. 1992, Seq. ID No. 1994, Seq. ID No. 2014, Seq. ID No. 2018, Seq. ID No. 2028, Seq. ID No. 2034, Seq. ID No. 2042, Seq. ID No. 2050, Seq. ID No. 2054, Seq. ID No. 2088, Seq. ID No. 2090, Seq. ID No. 2106, Seq. ID No. 2116, Seq. ID No. 2122, Seq. ID No. 2128, Seq. ID No. 2152, Seq. ID No. 2160, Seq. ID No. 2172, Seq. ID No. 2174, Seq. ID No. 2178, Seq. ID No. 2188, Seq. ID No. 2238, Seq. ID No. 2240, Seq. ID No. 2246, Seq. ID No. 2250, Seq. ID No. 2272, Seq. ID No. 2284, Seq. ID No. 2290, Seq. ID No. 2292, Seq. ID No. 2294, Seq. ID No. 2296, Seq. ID No. 2304, Seq. ID No. 2306, Seq. ID No. 2308, Seq. ID No. 2318, Seq. ID No. 2320, Seq. ID No. 2322, Seq. ID No. 2324, Seq. ID No. 2326, Seq. ID No. 2328, Seq. ID No. 2334, Seq. ID No. 2344, Seq. ID No. 2348, Seq. ID No. 2350, Seq. ID No. 2352, Seq. ID No. 2354, Seq. ID No. 2356, Seq. ID No. 2358, Seq. ID No. 2366, Seq. ID No. 2390, Seq. ID No. 2392, Seq. ID No. 2408, Seq. ID No. 2420, Seq. ID No. 2422, Seq. ID No. 2428, Seq. ID No. 2430, Seq. ID No. 2434, Seq. ID No. 2450, Seq. ID No. 2460, Seq. ID No. 2490, Seq. ID No. 2498, Seq. ID No. 2504, Seq. ID No. 2508, Seq. ID No. 2516, Seq. ID No. 2524, Seq. ID No. 2526, Seq. ID No. 2532, Seq. ID No. 2536, Seq. ID No. 2538, Seq. ID No. 2542, Seq. ID No. 2544, Seq. ID No. 2546, Seq. ID No. 2556, Seq. ID No. 2558, Seq. ID No. 2570, Seq. ID No. 2572, Seq. ID No. 2584, Seq. ID No. 2592, Seq. ID No. 2598, Seq. ID No. 2600, Seq. ID No. 2602, Seq. ID No. 2608, Seq. ID No. 2612, Seq. ID No. 2622, Seq. ID No. 2630, Seq. ID No. 2652, Seq. ID No. 2680, Seq. ID No. 2694, Seq. ID No. 2702, Seq. ID No. 2704, Seq. ID No. 2706, Seq. ID No. 2708, Seq. ID No. 2732, Seq. ID No. 2734, Seq. ID No. 2784, Seq. ID No. 2786, Seq. ID No. 2814, Seq. ID No. 2816, Seq. ID No. 2824, Seq. ID No. 2836, Seq. ID No. 2838, Seq. ID No. 2842, Seq. ID No. 2854, Seq. ID No. 2874, Seq. ID No. 2876, Seq. ID No. 2882, Seq. ID No. 2906, Seq. ID No. 2936, Seq. ID No. 2938, Seq. ID No. 2940, Seq. ID No. 2942, Seq. ID No. 2948, Seq. ID No. 2950, Seq. ID No. 2970, Seq. ID No. 2974, Seq. ID No. 2978, Seq. ID No. 2982, Seq. ID No. 2988, Seq. ID No. 2992, Seq. ID No. 2996, Seq. ID No. 2998, Seq. ID No. 3006, Seq. ID No. 3008, Seq. ID No. 3014, Seq. ID No. 3024, Seq. ID No. 3026, Seq. ID No. 3028, Seq. ID No. 3030, Seq. ID No. 3032, Seq. ID No. 3044, Seq. ID No. 3056, Seq. ID No. 3064, Seq. ID No. 3072, Seq. ID No. 3074, Seq. ID No. 3076, Seq. ID No. 3078, Seq. ID No. 3124, Seq. ID No. 3146, Seq. ID No. 3156, Seq. ID No. 3158, Seq. ID No. 3164, Seq. ID No. 3184, Seq. ID No. 3194, Seq. ID No. 3202, Seq. ID No. 3214, Seq. ID No. 3216, Seq. ID No. 3218, Seq. ID No. 3220, Seq. ID No. 3242, Seq. ID No. 3244, Seq. ID No. 3246, Seq. ID No. 3250, Seq. ID No. 3258, Seq. ID No. 3262, Seq. ID No. 3270, Seq. ID No. 3276, Seq. ID No. 3298, Seq. ID No. 3318, Seq. ID No. 3324, Seq. ID No. 3338, Seq. ID No. 3340, Seq. ID No. 3350, Seq. ID No. 3352, Seq. ID No. 3354, Seq. ID No. 3358, Seq. ID No. 3360, Seq. ID No. 3378, Seq. ID No. 3390, Seq. ID No. 3392, Seq. ID No. 3396, Seq. ID No. 3406, Seq. ID No. 3422, Seq. ID No. 3426, Seq. ID No. 3450, Seq. ID No. 3452, Seq. ID No. 3454, Seq. ID No. 3456, Seq. ID No. 3458, Seq. ID No. 3464, Seq. ID No. 3482, Seq. ID No. 3492, Seq. ID No. 3494, Seq. ID No. 3504, Seq. ID No. 3506, Seq. ID No. 3528, Seq. ID No. 3594, Seq. ID No. 3596, Seq. ID No. 3622, Seq. ID No. 3626, Seq. ID No. 3636, Seq. ID No. 3680, Seq. ID No. 3724, Seq. ID No. 3728, Seq. ID No. 3746, Seq. ID No. 3754, Seq. ID No. 3756, Seq. ID No. 3758, Seq. ID No. 3762, Seq. ID No. 3764, Seq. ID No. 3766, Seq. ID No. 3784, Seq. ID No. 3794, Seq. ID No. 3800, Seq. ID No. 3814, Seq. ID No. 3838, Seq. ID No. 3840, Seq. ID No. 3850, Seq. ID No. 3852, Seq. ID No. 3854, Seq. ID No. 3860, Seq. ID No. 3862, Seq. ID No. 3864, Seq. ID No. 3866, Seq. ID No. 3880, Seq. ID No. 3890, Seq. ID No. 3892, Seq. ID No. 3904, Seq. ID No. 3926, Seq. ID No. 3964, Seq. ID No. 3974, Seq. ID No. 3976, Seq. ID No. 4006, Seq. ID No. 4026, Seq. ID No. 4028, Seq. ID No. 4040, Seq. ID No. 4042, Seq. ID No. 4044, Seq. ID No. 4046, Seq. ID No. 4048, Seq. ID No. 4062, Seq. ID No. 4072, Seq. ID No. 4074, Seq. ID No. 4080, Seq. ID No. 4082, Seq. ID No. 4084, Seq. ID No. 4102, Seq. ID No. 4104, Seq. ID No. 4112, Seq. ID No. 4134, Seq. ID No. 4138, Seq. ID No. 4140, Seq. ID No. 4146, Seq. ID No. 4152, Seq. ID No. 4222, Seq. ID No. 4224, Seq. ID No. 4226, Seq. ID No. 4228, Seq. ID No. 4232, Seq. ID No. 4242, Seq. ID No. 4248, Seq. ID No. 4254, Seq. ID No. 4258, Seq. ID No. 4262, Seq. ID No. 4308, Seq. ID No. 4312, Seq. ID No. 4314, Seq. ID No. 4344, Seq. ID No. 4380, Seq. ID No. 4386, Seq. ID No. 4390, Seq. ID No. 4440, Seq. ID No. 4470, Seq. ID No. 4474, Seq. ID No. 4482, Seq. ID No. 4484, Seq. ID No. 4486, Seq. ID No. 4498, Seq. ID No. 4516, Seq. ID No. 4534, Seq. ID No. 4588, Seq. ID No. 4640, Seq. ID No. 4644, Seq. ID No. 4682, Seq. ID No. 4706, Seq. ID No. 4708, Seq. ID No. 4710, Seq. ID No. 4712, Seq. ID No. 4716, Seq. ID No. 4718, Seq. ID No. 4738, Seq. ID No. 4760, Seq. ID No. 4814, Seq. ID No. 4828, Seq. ID No. 4870, Seq. ID No. 4872, Seq. ID No. 4874, Seq. ID No. 4876, Seq. ID No. 4920, Seq. ID No. 4932, Seq. ID No. 4950, Seq. ID No. 4952, Seq. ID No. 4988, Seq. ID No. 5032, Seq. ID No. 5062, Seq. ID No. 5086, Seq. ID No. 5104, Seq. ID No. 5124, Seq. ID No. 5130, Seq. ID No. 5132, Seq. ID No. 5136, Seq. ID No. 5138, Seq. ID No. 5142, Seq. ID No. 5166, Seq. ID No. 5176, Seq. ID No. 5200, Seq. ID No. 5206, Seq. ID No. 5208, Seq. ID No. 5214, Seq. ID No. 5220, Seq. ID No. 5224, Seq. ID No. 5268, Seq. ID No. 5282, Seq. ID No. 5386, Seq. ID No. 5388, Seq. ID No. 5414, Seq. ID No. 5416, Seq. ID No. 5434, Seq. ID No. 5454, Seq. ID No. 5460, Seq. ID No. 5462, Seq. ID No. 5464, Seq. ID No. 5466, Seq. ID No. 5492, Seq. ID No. 5498, Seq. ID No. 5510, Seq. ID No. 5514, Seq. ID No. 5526, Seq. ID No. 5532, Seq. ID No. 5570, Seq. ID No. 5588, Seq. ID No. 5596, Seq. ID No. 5598, Seq. ID No. 5610, Seq. ID No. 5612, Seq. ID No. 5622, Seq. ID No. 5624, Seq. ID No. 5634, Seq. ID No. 5638, Seq. ID No. 5644, Seq. ID No. 5650, Seq. ID No. 5660, Seq. ID No. 5684, Seq. ID No. 5686, Seq. ID No. 5700, Seq. ID No. 5706, Seq. ID No. 5710, Seq. ID No. 5730, Seq. ID No. 5734, Seq. ID No. 5764, Seq. ID No. 5766, Seq. ID No. 5768, Seq. ID No. 5772, Seq. ID No. 5784, Seq. ID No. 5792, Seq. ID No. 5798, Seq. ID No. 5886, Seq. ID No. 5890, Seq. ID No. 5894, Seq. ID No. 5896, Seq. ID No. 5900, Seq. ID No. 5902, Seq. ID No. 5906, Seq. ID No. 5910, Seq. ID No. 5922, Seq. ID No. 5924, Seq. ID No. 5928, Seq. ID No. 5940, Seq. ID No. 6028, Seq. ID No. 6044, Seq. ID No. 6048, Seq. ID No. 6060, Seq. ID No. 6068, Seq. ID No. 6090, Seq. ID No. 6092, Seq. ID No. 6108, Seq. ID No. 6112, Seq. ID No. 6118, Seq. ID No. 6162, Seq. ID No. 6164, Seq. ID No. 6166, Seq. ID No. 6170, Seq. ID No. 6184, Seq. ID No. 6186, Seq. ID No. 6190, Seq. ID No. 6192, Seq. ID No. 6198, Seq. ID No. 6204, Seq. ID No. 6206, Seq. ID No. 6210, Seq. ID No. 6222, Seq. ID No. 6224, Seq. ID No. 6226, Seq. ID No. 6228, Seq. ID No. 6230, Seq. ID No. 6236, Seq. ID No. 6238, Seq. ID No. 6244, Seq. ID No. 6246, Seq. ID No. 6250, Seq. ID No. 6254, Seq. ID No. 6264, Seq. ID No. 6266, Seq. ID No. 6274, Seq. ID No. 6276, Seq. ID No. 6286, Seq. ID No. 6290, Seq. ID No. 6302, Seq. ID No. 6304, Seq. ID No. 6364, Seq. ID No. 6378, Seq. ID No. 6382, Seq. ID No. 6384, Seq. ID No. 6416, Seq. ID No. 6428, Seq. ID No. 6432, Seq. ID No. 6474, Seq. ID No. 6498, Seq. ID No. 6572, Seq. ID No. 6582, Seq. ID No. 6594, Seq. ID No. 6600, Seq. ID No. 6632, and Seq. ID No.
 6640. 56. An isolated polypeptide encoded by a polynucleotide comprising a nucleotide sequence having at least about 70% identity to a nucleotide sequence contained within SEQ ID NO: 6651, a complement thereof, a degenerate variant thereof, and a fragment thereof.
 57. A recombinant expression vector comprising a nucleotide sequence having at least about 70% identity to a nucleotide sequence chosen from one of the odd numbered sequences set out in SEQ ID NO: 1 through SEQ ID NO: 6649, a complement thereof, a degenerate variant thereof, and a fragment thereof.
 58. The vector of claim 57, wherein the polynucleotide is selected from the group consisting of genomic DNA, cDNA, and RNA.
 59. The vector of claim 58, wherein the polynucleotide comprises heterologous nucleotide sequences.
 60. The vector of claim 58, wherein the polynucleotide is operatively linked to one or more gene expression regulatory elements.
 61. The vector of claim 60, wherein the polynucleotide encodes a polypeptide comprising an amino acid sequence having at least about 70% identity to an amino acid sequence chosen from one of even numbered sequences set out in SEQ ID NO: 2 through SEQ ID NO: 6650, a biological equivalent thereof, and a fragment thereof.
 62. The vector of claim 57, wherein the vector is a plasmid.
 63. A genetically engineered host cell, transfected, transformed or infected with the vector of claim
 57. 64. The host cell of claim 63, wherein the host cell is a bacterial cell.
 65. The host cell of claim 64, wherein the polynucleotide is expressed to produce the encoded polypeptide, a biological equivalent thereof, or a fragment thereof.
 66. An antibody specific for a polypeptide encoded by an Alloiococcus otitidis polynucleotide chosen from one of the odd numbered sequences from SEQ ID NO: 1 through SEQ ID NO: 6649, a complement thereof, a fragment thereof, and a degenerate variant thereof.
 67. An antibody specific for an Alloiococcus otitidis polypeptide chosen from one of even numbered sequence listings set out in SEQ ID NO: 2 through SEQ ID NO: 6650, a complement thereof, a biological equivalent thereof, and a fragment thereof.
 68. The antibody of claim 66, wherein the antibody is selected from the group consisting of monoclonal, polyclonal, chimeric, humanized and single chain.
 69. The antibody of claim 67, wherein the antibody is selected from the group consisting of monoclonal, polyclonal, chimeric, humanized and single chain.
 70. The antibody of claim 66, wherein the antibody is monoclonal.
 71. The antibody of claim 67, wherein the antibody is monoclonal.
 72. The antibody of claim 66, wherein the antibody is humanized.
 73. The antibody of claim 67, wherein the antibody is humanized.
 74. An immunogenic composition comprising a polypeptide having an amino acid a sequence chosen from one of even numbered sequence listings set out in SEQ ID NO: 2 through SEQ ID NO: 6650, a complement thereof, a biological equivalent thereof, and a fragment thereof.
 75. The immunogenic composition of claim 74, further comprising a pharmaceutically acceptable carrier.
 76. The immunogenic composition of claim 74, further comprising one or more adjuvants.
 77. The immunogenic composition of claim 74, wherein the polypeptide is further defined as: (a) an Alloiococcus otitidis polypeptide predicted by SignalP algorithm analysis as having met all four criteria set out in the SignalP algorithm for a polypeptide having a signal peptide and predicted by HMM Signal P algorithm analysis as having a signal peptide; (b) an Alloiococcus otitidis polypeptide predicted by SignalP algorithm analysis as having met three of the four criteria set out in the SignalP algorithm for a polypeptide having a signal peptide and predicted by HMM Signal P algorithm analysis as having a signal peptide; (c) an Alloiococcus otitidis polypeptide predicted by HMM SignalP algorithm analysis as having a signal peptide; (d) an Alloiococcus otitidis polypeptide predicted by HMM SignalP algorithm analysis as being a non-secretory protein; (e) an Alloiococcus otitidis polypeptide identified by BlastP analysis; (f) an Alloiococcus otitidis polypeptide identified by Pfam analysis; (g) an Alloiococcus otitidis polypeptide identified using proteomics methodology as sharing homology with surface exposed proteins of Streptococcus pneumoniae; (h) an Alloiococcus otitidis lipoprotein; (i) an Alloiococcus otitidis polypeptide having a LPXTG motif, wherein the polypeptide is covalently attached to the peptidoglycan layer; (j) an Alloiococcus otitidis polypeptide, wherein the polypeptide is non-covalently associated with the peptidoglycan layer; (k) an Alloiococcus otitidis polypeptide having an RGDX motif wherein X is not a proline residue; (l) an Alloiococcus otitidis polypeptide predicted by BlastP as being involved in capsule biosynthesis and transport; (m) an Alloiococcus otitidis polypeptide identified by BlastP as being localized within the capsule loci of the Alloiococcus otitidis genome; (n) an Alloiococcus otitidis polypeptide predicted by BlastP as being associated with sporulation; (o) an Alloiococcus otitidis polypeptide encoded by unique ORFs identified by BlastP analysis as having a BlastP ‘E Value’ of >e⁻¹⁰; (p) an Alloiococcus otitidis polypeptide identified by Glimmer™ ORF finder program; (q) an Alloiococcus otitidis polypeptide identified by GeneMark™ ORF finder program; (r) an Alloiococcus otitidis polypeptide identified by an ORF finder program that searches for an ATG, GTG or TTG start codon between a Stop-Stop region; and (s) an Alloiococcus otitidis polypeptide identified by an ORF finder program that searches for a transmembrane domain between two Stop codons and a Stop codon immediately upstream of this transmembrane region.
 78. The immunogenic composition of claim 77, wherein the polypeptide further comprises heterologous amino acids.
 79. The immunogenic composition of claim 77, wherein the polypeptide is a fusion polypeptide.
 80. The immunogenic composition of claim 77, wherein the polypeptide is encoded by a polynucleotide comprising a nucleotide sequence having at least about 70% identity to a nucleotide sequence chosen from one of odd numbered sequence listings set out in SEQ ID NO: 1 through SEQ ID NO: 6649, a degenerate variant thereof, or a fragment thereof.
 81. The immunogenic composition of claim 8D, wherein the polynucleotide further comprises heterologous nucleotides.
 82. An immunogenic composition comprising a polynucleotide having a nucleotide sequence chosen from one of one of odd numbered sequence listings set out in SEQ ID NO: 1 through SEQ ID NO: 6649, a degenerate variant thereof, or a fragment thereof and is comprised in an expression vector.
 83. The immunogenic composition of claim 82, wherein the vector is plasmid DNA.
 84. The immunogenic composition of claim 83, wherein the polynucleotide comprises heterologous nucleotides.
 85. The immunogenic composition of claim 83, wherein the polynucleotide is operatively linked to one or more gene expression regulatory elements.
 86. The immunogenic composition of claim 85, wherein the polynucleotide directs the expression of a neutralizing epitope of Alloiococcus otitidis.
 87. The immunogenic composition of claim 86, further comprising one or more adjuvants.
 88. A pharmaceutical composition comprising a polypeptide and a pharmaceutically acceptable carrier, wherein the polypeptide comprises an amino acid chosen from one of even numbered sequence listings set out in SEQ ID NO: 2 through SEQ ID NO: 6650, a complement thereof, a biological equivalent thereof, and a fragment thereof.
 89. The pharmaceutical composition of claim 88, wherein the polypeptide is further defined as: (a) an Alloiococcus otitidis polypeptide predicted by SignalP algorithm analysis as having met all four criteria set out in the SignalP algorithm for a polypeptide having a signal peptide and predicted by HMM SignalP algorithm analysis as having a signal peptide; (b) an Alloiococcus otitidis polypeptide predicted by SignalP algorithm analysis as having met three of the four criteria set out in the SignalP algorithm for a polypeptide having a signal peptide and predicted by HMM SignalP algorithm analysis as having a signal peptide; (c) an Alloiococcus otitidis polypeptide predicted by HMM SignalP algorithm analysis as having a signal peptide; (d) an Alloiococcus otitidis polypeptide predicted by HMM SignalP algorithm analysis as being a non-secretory protein; (e) an Alloiococcus otitidis polypeptide identified by BlastP analysis; (f) an Alloiococcus otitidis polypeptide identified by Pfam analysis; (g) an Alloiococcus otitidis polypeptide identified using proteomics methodology as sharing homology with surface exposed proteins of Streptococcus pneumoniae; (h) an Alloiococcus otitidis lipoprotein; (i) an Alloiococcus otitidis polypeptide having a LPXTG motif, wherein the polypeptide is covalently attached to the peptidoglycan layer; (j) an Alloiococcus otitidis polypeptide, wherein the polypeptide is non-covalently associated with the peptidoglycan layer; (k) an Alloiococcus otitidis polypeptide having an RGDX motif wherein X is not a proline residue; (l) an Alloiococcus otitidis polypeptide predicted by BlastP as being involved in capsule biosynthesis and transport; (m) an Alloiococcus otitidis polypeptide identified by BlastP as being localized within the capsule loci of the Alloiococcus otitidis genome; (n) an Alloiococcus otitidis polypeptide predicted by BlastP as being associated with sporulation; (o) an Alloiococcus otitidis polypeptide encoded by unique ORFs identified by BlastP analysis as having a BlastP ‘E Value’ of >e⁻¹⁰; (p) an Alloiococcus otitidis polypeptide identified by Glimmer™ ORF finder program; (q) an Alloiococcus otitidis polypeptide identified by GeneMark™ ORF finder program; (r) an Alloiococcus otitidis polypeptide identified by an ORF finder program that searches for an ATG, GTG or TTG start codon between a Stop-Stop region; and (s) an Alloiococcus otitidis polypeptide identified by an ORF finder program that searches for a transmembrane domain between two Stop codons and a Start codon immediately upstream of this transmembrane region.
 90. The pharmaceutical composition of claim 89, wherein the polypeptide further comprises heterologous amino acids.
 91. The pharmaceutical composition of claim 90, wherein the polypeptide is a fusion polypeptide.
 92. A DNA chip comprising an array of polynucleotides, wherein at least one of the polynucleotides comprise a nucleotide sequence chosen from one of one of odd numbered sequence listings set out in SEQ ID NO: 1 through SEQ ID NO: 6649, a complement thereof, a degenerate variant thereof, and a fragment thereof.
 93. A protein chip comprising an array of polypeptides, wherein at least one of the polypeptides comprises an amino acid sequence chosen from one of even numbered sequence listings set out in SEQ ID NO: 2 through SEQ ID NO: 6650, a biological equivalent thereof, or a fragment thereof.
 94. A method of immunizing against Alloiococcus otitidis comprising administering to a host an immunizing amount of an immunogenic composition comprising a polypeptide and a pharmaceutically acceptable carrier, wherein the polypeptide comprises an amino acid sequence chosen from one of even numbered sequence listings set out in SEQ ID NO: 2 through SEQ ID NO: 6650, a biological equivalent thereof, or a fragment thereof.
 95. The method of claim 94, wherein the polypeptide is a fusion polypeptide.
 96. The method of claim 94, further comprising an adjuvant.
 97. A method for the detection and/or identification of Alloiococcus otitidis in a biological sample comprising: (a) contacting the sample with an oligonucleotide probe of a polynucleotide comprising the nucleotide sequence chosen from one of odd numbered sequence listings set out in SEQ ID NO: 1 through SEQ ID NO: 6649, a degenerate variant thereof, or a fragment thereof, under conditions permitting hybridization; and (b) detecting the presence of hybridization complexes in the sample, wherein hybridization complexes indicate the presence of Alloiococcus otitidis in the sample.
 98. A method for the detection and/or identification of Alloiococcus otitidis in a biological sample comprising: (a) contacting the sample with an oligonucleotide primer of a polynucleotide comprising the nucleotide sequence chosen from one of odd numbered sequence listings set out in SEQ ID NO: 1 through SEQ ID NO: 6649, a degenerate variant thereof, or a fragment thereof, in the presence of nucleotides and a polymerase enzyme under conditions permitting primer extension; and (b) detecting the presence of primer extension products in the sample, wherein extension products indicate the presence of Alloiococcus otitidis in the sample.
 99. A method for the detection and/or identification of Alloiococcus otitidis in a biological sample comprising: (a) contacting the sample with an antibody specific for a polypeptide comprising an amino acid sequence chosen from one of even numbered sequence listings set out in SEQ ID NO: 2 through SEQ ID NO: 6650, a biological equivalent thereof, or a fragment thereof, under conditions permitting immune complex formation; and (b) detecting the presence of immune complexes in the sample, wherein immune complexes indicate the presence of Alloiococcus otitidis in the sample.
 100. A method for the detection and/or identification of antibodies to Alloiococcus otitidis in a biological sample comprising: (a) contacting the sample with a polypeptide comprising an amino acid sequence chosen from one of even numbered sequence listings set out in SEQ ID NO: 2 through SEQ ID NO: 6650, a biological equivalent thereof, Nor a fragment thereof, under conditions permitting immune complex formation; and (b) detecting the presence of immune complexes in the sample, wherein immune complexes indicate the presence of Alloiococcus otitidis in the sample.
 101. A kit comprising a container containing an isolated polynucleotide comprising an nucleotide sequence chosen from one of odd numbered sequence listing set out in SEQ ID NO: 1 through SEQ ID NO: 6649, a degenerate variant thereof, or a fragment thereof.
 102. The kit of claim 101, wherein the polynucleotide is a primer or a probe.
 103. The kit of claim 101, wherein the polynucleotide is a primer and the kit further comprises a container containing a polymerase.
 104. The kit of claim 103, wherein the kit further comprises a container containing dNTP.
 105. A kit comprising a container containing an antibody that immunospecifically binds to a polypeptide comprising the amino acid sequence chosen from one of even numbered sequence listings set out in SEQ ID NO: 2 through SEQ ID NO: 6650, a biological equivalent thereof, or a fragment thereof.
 106. A kit comprising a container containing an antibody that immunospecifically binds to a fusion polypeptide comprising at least the amino acid sequence chosen from one of even numbered sequence listings set out in SEQ ID NO: 2 through SEQ ID NO: 6650, a biological equivalent thereof, or a fragment thereof.
 107. A method for producing a polypeptide, which comprises culturing the genetically engineered host cell of claim 63 under conditions suitable to produce the polypeptide and recovering the polypeptide from the culture. 